Any measure for Taiwan's dengue control and surveillance? 感染症學 黎煥耀 教授 劉清泉...
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- Any measure for Taiwan's dengue control and surveillance?
07/10/17
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- Outline 96.6 96.7.18 Dengue Prevention and 35 Years of Vector
Control in Singapore Eng-Eong Ooi,* Kee-Tai Goh, and Duane J.
Gubler
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- (Dengue fever) ( 38 ) ( ) (hemorrhagic manifestations)
(leucopenia)
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- Aedes aegypti Aedes albopictus
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- Temperature, Virus Positivity and Anti- Dengue IgM, by Fever
Day Dengue IgMMean Max. TemperatureVirus Adapted from Figure 1 in
Vaughn et al., J Infect Dis, 1997; 176:322-30. Fever Day 0 20 40 60
80 100 Percent Virus Positive -4-3-2 0123456 39.5 39.0 38.5 38.0
37.5 37.0 Temperature (degrees Celsius) Dengue IgM (EIA units) 300
150 0 75 225
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- 1987 2006
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- 1987-2006
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- 96.6
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- 1. ( ) ( ) 2. ( ) ( ) ( ) / ( ) /
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- ( ) 24 24 ( ) ( ) 92 7 17 92 1 1
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- ( ) ( ) 5000 ( ) ( ) ( ) ( ) ( )
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- American Journal of Tropical Medicine & Hygiene
5-July-2007
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- 2006 11 23 11 20 11 23 (PCR) PCR 2006 96 5 25 23 5 236
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- ( ) ( ) ( )IgM IgG IgM IgG IgM
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- 96/7/18
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- 95/9/9
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- 96-99 95.2 96-99
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- 97-98
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- Dengue Prevention and 35 Years of Vector Control in Singapore
Eng-Eong Ooi,* Kee-Tai Goh, and Duane J. Gubler Emerging Infectious
Diseases www.cdc.gov/eid Vol. 12, No. 6, June 2006
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- Annual incidence dengue fever (DF) and dengue hemorrhagic fever
(DHF) and the premises index, Singapore,19662005.
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- Vector Control in Singapore The vector control program thus has
2 elements in addition to source reduction: Public education and
Law enforcement. The Destruction of Disease Bearing Insects Act of
1968 was enacted to discourage persons from intentionally or
unintentionally propagating mosquitoes.
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- Singapore have identified several factors that may have
contributed to this resurgence: lowered herd immunity,
children6.7%< adult42% Increasing virus transmission outside the
home, More clinically overt infection as a consequence of adult
infection, and A shift in the surveillance emphasis of the vector
control program.
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- Transmission Outside the Home In Singapore,however, the
incidence of DF/DHF is lower in children than in adults School-age
children were therefore 9 more likely to have antibodies to dengue
than were preschool children Women, who are more likely than men to
care for children at home, have a lower incidence of dengue, as
indicated by the male-to female disease ratio of 1.6:1
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- Proportion of indigenous dengue fever cases in patients 25
years of age, Singapore, 19772004.
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- Dengue in Adults As a consequence of lowered herd immunity and
transmission outside the home, cases in adults predominate in
Singapore. While most dengue infections, particularly primary
infections in young children, are mild or silent, infections in
adults are more likely to be clinically overt.
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- Shift in Surveillance Emphasis Responding to dengue cases and
clusters, however, has limited effectiveness in preventing virus
transmission, since such an approach ignores virus transmission
from persons with subclinical infection or mild undifferentiated
fever to uninfected mosquitoes. Only 30% of cases can be mapped to
a cluster. Most reported dengue cases occur outside known clusters.
No evidence shows that emergency control measures, particularly the
use of chemical insecticides, are effective after cases have
already been detected
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- Strengthening Regional Vector Control The Singapore experience
also underscores the fact that dengue control must be a regional
effort. Barring eradication of the mosquito vector, countries that
control dengue transmission are doomed to failure if neighboring
countries do nothing to prevent continued epidemic
transmission
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- Thank you for your attention