View
20
Download
0
Category
Preview:
DESCRIPTION
e stradiol supplementation. Figure S1. Growth chart of the patient. Actual height of the patient is plotted against the growth curve for Japanese girls (the mean, ± 1.0 SD and ± 2.0 SD). p = 0.78. p = 0.06. p = 0.20. p = 0.97. p = 0.02. p = 3.2×10 -7. p = 1.2×10 -7. - PowerPoint PPT Presentation
Citation preview
estradiol supplementation
Figure S1. Growth chart of the patient. Actual height of the patient is plotted against the growth curve for Japanese girls (the mean, ± 1.0 SD and ± 2.0 SD).
Series10
5
10
15
20
25
Series10
1
2
3
4
5
6
7
8
9 p = 1.1×10-
4
p = 2.0×10-
7
Rela
tive f
old
induct
ion
Rela
tive f
old
induct
ion
Figure S2. In vitro reporter assay using a luciferase vector containing the MITF promoter. The SOX10 expression vectors were transfected with (right panel) or without (left panel) the PAX3 expression vector. The results are expressed as the mean ± one standard deviation. The p.Pro169fsX117 mutant (MT) barely transactivated the MITF promoter and exerted no dominant-negative effects on the wildtype (WT) SOX10 protein. As controls for the expression vectors, an empty counterpart vector was transfected.
PAX3 (+)PAX3 (-)
p = 1.1×10-
13
p = 3.2×10-
7
p = 0.97
p = 0.06
p = 1.2×10-
7
p = 6.0×10-
8
p = 7.0×10-7
p = 0.02
p = 0.20
p = 0.78
WT (ng/well)
MT (ng/well)
0 20 20 10 0
0 0 20 10 20
WT (ng/well)
MT (ng/well)
0 20 20 10 0
0 0 20 10 20
Recommended