Protein(Structural(Metrics(for( Modelling(Presentation1.pptx Author M.Shajahan Gulam Razul Created...

Protein Structural Metrics for Modelling

• The 20 standard amino acids share a common structure but differ in their side chains. • Pep=de bonds link amino acid residues in a polypep=de.

General Structure of α-Amino Acid

Condensation of Two Amino Acids

Pep=de Bond

1°, 2°, 3° & 4° Structure

Peptide Bonds Assume Trans Conformation

Resonance of Peptide Bond

Extended Conformation of Polypeptide

Torsion Angles of Polypeptide Backbone

Steric Interference of Adjacent Peptide Groups

The α Helix

β Sheets

Antiparallel β Sheet

Ramachandran Diagram

Parallel β Sheet

Pleating of β Sheet

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