Capacidad univariada de las interleuquinas para diferenciar entre

Preview:

DESCRIPTION

Carlos Gabriel Contreras.Capacidad univariada de las interleuquinas para diferenciar entre EAS, AR y A

Citation preview

Capacidad univariada de las interleuquinas para diferenciar

entre EAS, AR y A.

Contrastes no parametricos.

Test Statisticsa,b

9,727 13,650 11,920 8,711 1,607 9,951

2 2 2 2 2 2

,008 ,001 ,003 ,013 ,448 ,007

Chi-Square

df

Asymp. Sig.

IL - 6 pg/ml IL - 1Bpg/ml IL - 8 pg/ml IL - 12 pg/ml TNF a pg/ml IL - 10 pg/ml

Kruskal Wallis Testa.

Grouping Variable: Grupo de pertenenciab.

Contrastes independientes de las IL.

Ranks

18 18,14 326,50

12 11,54 138,50

30

18 16,61 299,00

12 13,83 166,00

30

Grupo de pertenenciaEAS

AR

Total

EAS

AR

Total

IL - 1Bpg/ml

IL - 8 pg/ml

N Mean Rank Sum of Ranks

Test Statisticsb

60,500 88,000

138,500 166,000

-2,396 -,847

,017 ,397

,043a

,415a

Mann-Whitney U

Wilcoxon W

Z

Asymp. Sig. (2-tailed)

Exact Sig. [2*(1-tailedSig.)]

IL - 1Bpg/ml IL - 8 pg/ml

Not corrected for ties.a.

Grouping Variable: Grupo de pertenenciab.

Comparación de la IL 1B y la IL8 en EAS y AR.

Comparación de la IL 1B y la IL8 en EAS y OA.

Ranks

18 14,56 262,00

18 22,44 404,00

36

18 13,72 247,00

18 23,28 419,00

36

Grupo de pertenenciaEAS

OA

Total

EAS

OA

Total

IL - 1Bpg/ml

IL - 8 pg/ml

N Mean Rank Sum of Ranks

Test Statisticsb

91,000 76,000

262,000 247,000

-2,332 -2,723

,020 ,006

,024a

,006a

Mann-Whitney U

Wilcoxon W

Z

Asymp. Sig. (2-tailed)

Exact Sig. [2*(1-tailedSig.)]

IL - 1Bpg/ml IL - 8 pg/ml

Not corrected for ties.a.

Grouping Variable: Grupo de pertenenciab.

Comparación de la IL 1B y la IL8 en AR y OA

Ranks

12 9,75 117,00

18 19,33 348,00

30

12 9,50 114,00

18 19,50 351,00

30

Grupo de pertenenciaAR

OA

Total

AR

OA

Total

IL - 1Bpg/ml

IL - 8 pg/ml

N Mean Rank Sum of Ranks

Test Statisticsb

39,000 36,000

117,000 114,000

-3,229 -3,052

,001 ,002

,003a

,002a

Mann-Whitney U

Wilcoxon W

Z

Asymp. Sig. (2-tailed)

Exact Sig. [2*(1-tailedSig.)]

IL - 1Bpg/ml IL - 8 pg/ml

Not corrected for ties.a.

Grouping Variable: Grupo de pertenenciab.

Identificación de factores inmunológicos.

Análisis factorial.

KMO and Bartlett's Test

,646

68,542

15

,000

Kaiser-Meyer-Olkin Measure of SamplingAdequacy.

Approx. Chi-Square

df

Sig.

Bartlett's Test ofSphericity

Total Variance Explained

2,296 38,272 38,272 2,296 38,272 38,272

1,142 19,038 57,310 1,142 19,038 57,310

,972 16,199 73,510

,895 14,910 88,420

,514 8,570 96,989

,181 3,011 100,000

Component1

2

3

4

5

6

Total % of Variance Cumulative % Total % of Variance Cumulative %

Initial Eigenvalues Extraction Sums of Squared Loadings

Extraction Method: Principal Component Analysis.

Component Matrixa

-,198 -,433

,044 ,702

-,071 ,648

,909 -,156

,912 -,032

,770 ,130

IL - 6 pg/ml

IL - 1Bpg/ml

IL - 8 pg/ml

IL - 12 pg/ml

TNF a pg/ml

IL - 10 pg/ml

1 2

Component

Extraction Method: Principal Component Analysis.

2 components extracted.a.

Rotated Component Matrixa

-,173 -,444

,004 ,703

-,108 ,643

,916 -,103

,912 ,020

,761 ,174

IL - 6 pg/ml

IL - 1Bpg/ml

IL - 8 pg/ml

IL - 12 pg/ml

TNF a pg/ml

IL - 10 pg/ml

1 2

Component

Extraction Method: Principal Component Analysis. Rotation Method: Varimax with Kaiser Normalization.

Rotation converged in 3 iterations.a.

Rotated Component Matrixa

-,174 -,443

,006 ,703

-,107 ,643

,916 -,105

,912 ,018

,762 ,172

IL - 6 pg/ml

IL - 1Bpg/ml

IL - 8 pg/ml

IL - 12 pg/ml

TNF a pg/ml

IL - 10 pg/ml

1 2

Component

Extraction Method: Principal Component Analysis. Rotation Method: Quartimax with Kaiser Normalization.

Rotation converged in 3 iterations.a.

Component Matrixa

-,198 -,433

,044 ,702

-,071 ,648

,909 -,156

,912 -,032

,770 ,130

IL - 6 pg/ml

IL - 1Bpg/ml

IL - 8 pg/ml

IL - 12 pg/ml

TNF a pg/ml

IL - 10 pg/ml

1 2

Component

Extraction Method: Principal Component Analysis.

2 components extracted.a.

Análisis de función discriminante.

Factor inmune/Linfocito T como mejor discriminante entre EAS, AS y OA

Resumen de la función discriminante.

Variables Entered/Removeda,b,c,d

Factorinmunitario/Linfocito T.

,580 1 2 45,000 16,291 2 45,000 ,000

Step1

Entered Statistic df1 df2 df3 Statistic df1 df2 Sig.

Exact F

Wilks' Lambda

At each step, the variable that minimizes the overall Wilks' Lambda is entered.

Maximum number of steps is 4.a.

Minimum partial F to enter is 3.84.b.

Maximum partial F to remove is 2.71.c.

F level, tolerance, or VIN insufficient for further computation.d.

Curvas COR

Factores Macrófago y linfocito T

Curva COR para OACase Processing Summary

18

30

Grupo de pertenenciaPositivea

Negative

Valid N(listwise)

Larger values of the test result variable(s) indicatestronger evidence for a positive actual state.

The positive actual state is OA.a.

Curva COR para OA

Case Processing Summary

12

36

Grupo de pertenenciaPositivea

Negative

Valid N(listwise)

Larger values of the test result variable(s) indicatestronger evidence for a positive actual state.

The positive actual state is AR.a.

Curva COR para EASCase Processing Summary

18

30

Grupo de pertenenciaPositivea

Negative

Valid N(listwise)

Larger values of the test result variable(s) indicatestronger evidence for a positive actual state.

The positive actual state is EAS.a.

Perfiles de compromiso inmunológico.

Indicadores moleculares de gravedad.

IL-6

IL 1B

IL 8

TNF a e IL 12

IL 10

Factor inmunitario Macrófago.

Factor inmunitario Linfocito T

Correspondence Table

15 3 18

12 0 12

9 9 18

36 12 48

Grupo de pertenenciaEAS

AR

OA

Active Margin

Perfil decompromiso

inmunològicobajo

Perfil decompromiso

inmunològicoalto. Active Margin

Compromiso inmunològico

Summary

,471 ,222 1,000 1,000 ,113 ,471

,222 10,667 ,005a 1,000 1,000

Dimension1

Total

SingularValue Inertia Chi Square Sig. Accounted for Cumulative

Proportion of Inertia

StandardDeviation Correlation

Confidence SingularValue

2 degrees of freedoma.

Análisis de correspondencia entre EAS, AR, OA y perfiles de

compromiso inmune.

Recommended