SIngularity University - Palestra Eduardo Barbato

MINHA EXPERIÊNCIA SINGULARUm retrato de 10 dias no Vale do Silício na SINGULARITY UNIVERSITY.

Vice-presidente de Estratégia Eduardo [email protected]

EDUARDO BARBATOSINGULARITY UNIVERSITY

COMO AS TECNOLOGIAS EXPONENCIAIS VÃO AFETAR NOSSO NEGÓCIO

“TODO HOMEM TOMA OS LIMITES DE SEU PRÓPRIO CAMPO DE VISÃO COMO OS LIMITES DO MUNDO”.

Arthur Schopenhauer


INTRODUÇÃO

“Colaboração é essencial para inovação”

“Como fazer um mestrado quando o programa fica mais velho a cada dia. A tecnologia anda mais rápido.”


INTRODUÇÃO

Spaguetti + Marshmallow


INTRODUÇÃO

. As repostas são ilimitadas

. Inovação (diferente) - tentar ser bem sucedido o tempo inteiro

. O problema de algumas empresas é não querer falhar, aprender, tentar novamente e aí sim, ser bem sucedido.

Spaguetti + Masshimalow


INTRODUÇÃO

Spaguetti + Masshimalow

THERE IS NO RIGHT ANWSER.

. As repostas são ilimitadas

. Inovação (diferente) - tentar ser bem sucedido o tempo inteiro

. O problema de algumas empresas é não querer falhar, aprender, tentar novamente e aí sim, ser bem sucedido.


INTRODUÇÃO A Lanterna X app do IPHONEMuitas empresas

tem expertise para fazer uma câmera,

mas milhões podem fazer apps de câmera.


INTRODUÇÃO A Lanterna X app do IPHONEMuitas empresas

tem expertise para fazer uma câmera,

mas milhões podem fazer apps de câmera.

Tecnologia exponencial.


INTRODUÇÃO Veremos cada vez mais o comportamento de aparecimento de uma nova indústria e o desaparecimento em pouco tempo. Indústria de social media, por exemplo.


INTRODUÇÃO “Are you working on something that can change the world? Yes or no? The answer for 99.99999% of people in the world is ‘no.’ I think we need to be training people on how to change the world. Obviously technologies are the way to do that. That’s what we’ve seen in the past, that’s what driven all the change.”

Larry Page, Google Co-Founder

at SU founding conference

INTRODUÇÃO


THE HISTORY OF TECHNOLOGYThe history of technology

6000

5000

4000

0

1000

2000

3000

Population (millions)

Time (years)–9000 –6000 –4000 –3000 –2000 1000 2000

Agricultural revolution

PotteryPlow

Irrigation

1st city

Metallurgy

Writing

MathematicsPeak of Greece

Peak of Rome

2nd Agricultural Revolution

Industrial Revolution

Airplane

High-speed computers

Man lands on Moon

Genome project

0

Watt Engine

Railroads

Germ Theory

Telephone

Automobile

Penicillin

DNA discovered

Nuclear Energy

PCs

Internet

Saturday, March 9, 13

INTRODUÇÃO


STRESS & OPPORTUNITYStress & Opportunity


INTRODUÇÃO


THE EXPONENTIAL GROWTH OF INFORMATIONThe Exponential Growth of Information…

5 Exobytes = 5 Billion Gigabytes


INTRODUÇÃO




! From the start of time ! 2003


INTRODUÇÃO





! in 2010 ~ 2 Days


INTRODUÇÃO





! in 2010 ~ 2 Days

! in 2013 ~


INTRODUÇÃO





! in 2010 ~ 2 Days

! in 2013 ~ 10 minutes


INTRODUÇÃO


INTERNET OF THINGS: 50B DEVICES BY 2025Internet of Things: 50B devices by

2025


INTRODUÇÃO


>1 TRILLIOON CONNECTED DEVICES USING LOW BANDWIDTH

HP’s CeNSE INITIATIVE

50% OF DATA TRAFFIC BY 2030

M2M COMMUNICATION WILL BE OVER

INTRODUÇÃO


Page 11

HTML (text) Video Social Profiles

Location

Quantified Self

Health Data

Sensor Networks

Internet of Things

New information layers


NEW INFORMATION LAYERS


INTRODUÇÃO


INTRODUÇÃO


Innovation Lab

3D#Printed#Guitar#INNOVATION LABInnovation Lab

3D#Printed#Guitar#

Innovation Lab

3D#Printed#Guitar#

3D PRINTED GUITAR

Innovation Lab

3D#Printed#Guitar#

INTRODUÇÃO


Dr. Gordon Moore

Moore Density

Cost

1965

DR. GORDON MOORE

INTRODUÇÃO


Moore's Law (Actual) 1970 -74

256

1K

4K

MOORE’S LAW (ACTUAL) 1970-74

INTRODUÇÃO


MOORE’S LAW & PHOTOLITHOGRAPHYMoore's Law & Photolithography

first microcomputer (1/10th human hair diameter)

100 Mhz Pentium 2 Ghz Penryn

Moore

INTRODUÇÃO


SMALLER AND FASTER (C.A 2005)Smaller and Faster (c.a. 2005)

W L

Speed = Gate (W/L)

INTRODUÇÃO


O CONCEITO DE SINGULARIDADE

INTRODUÇÃO


O ritmo de crescimento da inovação tem apenas de continuar a evoluir da mesma forma, até ser desenvolvida uma supermáquina capaz de acelerar ainda mais o ritmo de inovação (talvez mesmo criando uma máquina ainda mais inteligente, aumentando dramaticamente a quantidade de inteligência disponível na Terra), alcançando o ponto de feedback explosivo em que a dinâmica e complexidade do conhecimento e da tecnologia ficaria fora da esfera humana. Esse ponto fulcral e imprevisível é a Singularidade.

O Porque dos avanços:

INTRODUÇÃO


Mas há diversos pontos de vista, que chamam a nossa atenção para aspectos notáveis da reflexão atual acerca do impacto dessa eventualidade, e vários caminhos para a alcançar (software com capacidade para aprender, entidades artificiais surgidas por evolução de sistemas computacionais, integração do sistema nervoso humano com hardware, fusão de seres humanos e computadores através de interfaces ou redes computacionais auto-organizadas).

INTRODUÇÃO


Não nos limitemos ao ramo computacional. As ciências biológicas também poderão colocar ao nosso dispor meios para ampliar as capacidades humanas: manipulação genética, controle de características antes da fecundação e cultivo de órgãos in vitro são apenas algumas das possibilidades.

O aspecto fundamental da Singularidade é a alteração da ecologia tecnológica: o forte ritmo de inovação transformaria continuamente o mundo e o próprio ser humano, tornando inútil (ou extremamente difícil) o esforço de previsão. O surgimento de uma super-inteligência tornaria o mundo e a tecnologia infinitamente mais complexos.

INTRODUÇÃO


O QUE ISSO MUDA A INDÚSTRIA?

Ice Water cold Water hot Steam

Money

Commerce

Comms

IT

Biology

Music

Society

Goats Paper Money Digital Money

Virtual Currency

Physical goods

Information goods ideas Attention

Snail mail Email IM & social feeds direct B2B

Hardware Software Internet Cloud Computing

Inorganic Organic Complex lifeforms

Synthetic life

Local performer

Recorded Music CDs Internet

streamClans or tribes

Nation states MNC, FTZ Facebook

Thursday, March 14, 13

INTRODUÇÃO



Steam

Water

Ice

GasNo structureFull expansion into spaceVery fast, very hotHard to contain/recapture

LiquidLimited structureExpansion to boundaryMedium fast, medium ‘hot’

SolidVery structuredLimited expansionSlow, cold


INTRODUÇÃO



Information Technologies causing the heat to rise

Communications is reducing the space between molecules

Everything collides with everything else

We’re becoming high energy molecules

Turning domains into vapor


INTRODUÇÃO



Steam

Water

Ice


INTRODUÇÃO


O QUE TUDO ISSO TEM A VER COM A GENTE?

INTRODUÇÃO


54

Mainstream Media - threatened

Discovery via social media


MAINSTREAM MEDIA - THREATENED

DISCOVERY VIA SOCIAL MEDIA

INTRODUÇÃO


REAL ECONOMIC IMPACT

33

Real Economic Impact

Wiped out $65m… in 2004

Just in the SF Bay area

Craigslist – a small example


CRAIGLIST - A SMALL EXAMPLE

32

Shift from control to collaboration


SHIFT FROM CONTROL

TO COLLABORATION

CHRIS ANDERSONWIRED

58

Chris Anderson - Wired


INTRODUÇÃO


INTRODUÇÃO


THE RISE OF NETWORKED CURRENCIES

35

The rise of networked currencies

Prediction: By 2025, virtual currencies will compete with national currencies




Thursday, March 14, 13 35




35




PREDICTION:By 2025, virtual currencies will compete with national currencies

INTRODUÇÃO


INOVAÇÃO NO DNA

INTRODUÇÃO


ISSO É LOUCURA?


AS NOSSAS MUDANÇAS SÃO AS MENOS IMPORTANTES.

PREPARADOS?


O QUE VAMOS VER HOJE SUPERFICIALMENTE:

INTRODUÇÃO


INTRODUÇÃO



INTELIGÊNCIA ARTIFICIAL

“O cérebro não teve

upgrade e ainda veio com bugs”


INTELIGÊNCIA ARTIFICIAL“AI Vai roubar nossos jobs?

Temos muita criatividade para inventar o que fazer. Coisas

mais importantes para cuidar, meio ambiente, o planeta,

temos que ser imaginativos.”


HYBRID KNOWLEDGE SYSTEMSHYBRID KNOWLEDGE SYSTEMS




É SÓ A PONTA DO ICEBERG.será muito melhor.

INTELIGÊNCIA ARTIFICIAL GOOGLE GLASS




MOORE’S LAW COMES TO TRANSPORTATION



MOORE’S LAW COMES TO TRANSPORTATION

GOOGLE SELF CAR



INTELIGÊNCIA EM BUSCA: WOLFRAMALPHA

“Se a AI vai roubar todos os nossos Jobs, temos muita criatividade para inventar o que fazer. Temos coisas mais importantes para cuidar, como meio ambiente etc. Temos que ser imaginativos.”





AMBIENT INTELIGENCE CONCEPT




OBJECT TO OBJECT INTERACTIONS

ENVIRONMENT INTERACTIONS

PERSON TO PERSON INTERACTIONS




INTELIGÊNCIA ARTIFICIAL –13.7B years

The chemical emergence

–4B years

The biological evolution

–10B years

The cultural evolution

Now years

The technological evolution

Saturday, March 9, 13EDUARDO BARBATOSINGULARITY UNIVERSITY



GROK



GROK



“Um mundo com inteligência, mas sem os vícios dos humanos. Os homens mentiram anos e anos sobre o cigarro na década de 60. Disseram que não traria Câncer, mesmo sabendo. Isso não aconteceria numa máquina.”

Mataram pessoas. não eram inteligentes?



MEDGLE



BRAD TEMPLETON ENGENHEIRO GOOGLE



AI APPLICATIONS





IBM - WATSON



IBM - WATSON



IBM - WATSON



IBM - WATSON



Corruption Scientific Illiteracy

Hyper Discounting the Future

Brain Processing Limitations

Complexity and Speed of Events

Math &

Statistical Illiteracy

Special Interest Groups

Information Overload

Cognitive Biases



RJ10502 (ALM1211-004) November 13, 2012Computer Science

IBM Research Report

1014

Theodore M. Wong, Robert Preissl, Pallab Datta, Myron Flickner,Raghavendra Singh, Steven K. Esser, Emmett McQuinn,

Rathinakumar Appuswamy, William P. Risk, Horst D. Simon*, Dharmendra S. ModhaIBM Research Division

Almaden Research Center650 Harry Road

San Jose, CA 95120-6099USA

* Lawrence Berkeley National LabBerkeley, CA 94720

Research DivisionAlmaden - Austin - Beijing - Cambridge - Haifa - India - T. J. Watson - Tokyo - Zurich



530 billion neurons 1.37x1014 synapses



FROM CALCULATING MACHINES TO LEARNING DEVICES



O nosso cérebro é um universo desconhecido a ser explorado. NASA. As missões agora são outras.



AI APPLICATIONS



AI APPLICATIONS



AI APPLICATIONS



AI APPLICATIONS

http://www.wired.com/threatlevel/2007/03/ai_cited_for_un/



AI APPLICATIONS



AI APPLICATIONS - Saúde









AI APPLICATIONS



AI APPLICATIONS


ROBÓTICA

ROBÓTICA


ROBÓTICA ROBOT


ROBÓTICA


ROBÓTICA ROBOT


ROBÓTICA ROBOT


ROBÓTICA ROBOT


ROBÓTICA ROBOT


ROBÓTICA ROBOT

Alguns reflexos na nossa indústria


ROBÓTICA ROBOT

ROBOT É CULTURAL


ROBÓTICA


ROBÓTICA

ROBOT É CULTURAL


ROBÓTICA

SENSORS + ROBOTIC = SUCCESS

Cerébro é disparado pelo movimento

Eu mexo, então eu penso.


ROBÓTICA ROBOT

ROBOT É CULTURAL


ROBÓTICA ROBOT

ROBOT É CULTURAL


ROBÓTICA ROBOT

ROBOT É CULTURAL


ROBÓTICA ROBOT

ROBOT É CULTURAL


OVERVIEW AND APPLICATIONS

ROBÓTICA



ROBÓTICA


ROBÓTICAOVERVIEW AND APPLICATIONS

BREAKTHROUGHS_Face recognition, gesture recognition, and lip reading

_Voice recognition for single voice in noisy room with no near field microphone

_Situational awareness as a robot team member with humans-take emergency action or remain

unobtrusive as appropriate.

_Recognition of human expressions, emotions, and intent, incorporating facial appearance,

gestures, voice, and body language.

_Outdoor path finding , through various terrain w/o GPS

_$5000 to $100 cost drop in navigation & obstacle avoidance sensors

_Grasping of objects, with appropriate force and balance

_Object recognition with separation of backgrounds and shadows

_Smell and taste sensors

_5x improvement in battery energy density over Li-Ion batteries



_Use of Robotic Weapons - What level of autonomy do we give to a system that has lethal force?

_If robots display behavior consistent with sentience, should they be given rights and

responsabilities that correspond to their perceived intelligence?

_Who is responsible when an intelligent robot malfunctions, injuring people or property -

manufacturer, owner, or robot?

_Do we put limits on how intelligent we allow mechanical systems to become?

How could we enforce limits?

_As robots enter private homes in greater numbers, what are the privacy implications?

_Do we want doctors and therapists to monitor us via robots to be sure we are OK at home?

Who gets to look, listen and roam your hallways?

CONTROVERSIES



_Generally people think that today’s robots are much smarter and more capable than they really are

_Many people erroneously believe that, outside the laboratory, robots can autonomously: . Carry on normal human conversations . Easily open doors . Rapidly cross a cluttered room . Clear a table . Wash dishes . Fold clothes

_These activities are often shown in video demos, without stating that conditions were carefully pre-arranged and that, often, the playback speed is 10%

MISCONCEPTIONS



_Leading do-it-yourself (DIY) robots: Helo by Singularity University Bilibot by Garratt Gallagher Turtlebot by Willow Garage Mindstorms by LEGO Create, iRobot

_Research Labs _Carnegie Mellon University’s Robotics Institute, AI Labs _MIT AI Lab. Media Lab, Robotics _Stanford, AI Laboratory (Robotics LAB), KSL, HSTAR _Google Research _Microsoft Robotics _Willow Garage

TOOLS & RESOURCES

3D PRINTING


3D PRINTING MIMEÓGRAFO>XEROX>IMPRESSORA

3D IMPRESSORA


3D PRINTING

ADOÇÃO EXPONENCIAL - COMO FICA A INDÚSTRIA?


3D PRINTING



3D PRINTING



3D PRINTING



3D PRINTING



3D PRINTING



3D PRINTING



3D PRINTING



3D PRINTING



3D PRINTING



3D PRINTING




3D PRINTING



3D PRINTING



3D PRINTING



3D PRINTING



3D PRINTING

CADEIA PRODUTIVA, LEGISLAÇÃO, LOGÍSTICA, RELAÇÃO DE CONSUMO. TUDO MUDA. ESTAMOS NOS PREPARANDO? AO MENOS PENSANDO NISSO?


3D PRINTING

ADOÇÃO EXPONENCIAL - Ciclo de inovação

Impossible - Impractical- Possible - Expected - Requered


3D PRINTING

MINI BARBATO


3D PRINTING

ADOÇÃO EXPONENCIAL - Ciclo de inovação

NANOTECNOLOGIAEDUARDO BARBATOSINGULARITY UNIVERSITY


NANOTECNOLOGIA


Invisível aos olhos e ao mindset


NANOTECNOLOGIA


Já está em uso para aplicações simples


NANOTECNOLOGIA


APLICADO A NEUROCIÊNCIA


NANOTECNOLOGIA


APLICADO A NEUROCIÊNCIA


NANOTECNOLOGIA


NA MEDICINA


NANOTECNOLOGIA


NA PRÁTICA

http://www.samsung.com/ph/consumer/learningresources/

washingmachine/silver_nano/site.html

http://www.apple.com/br/

http://www.samsung.com/ph/consumer/learningresources/washingmachine/silver_nano/site.html


NANOTECNOLOGIA


NANOTECNOLOGIA


NANOTECNOLOGIA


NANOTECNOLOGIA


NANOTECNOLOGIA


NANOTECNOLOGIA


NANOTECNOLOGIA



NANOTECNOLOGIAMOLECULAR


NANOTECNOLOGIA


BREAKTHROUGHS

_Desktop nanofactory able to manufacture a copy of itself in under 24 hours cheap feedstock is

commercially avaiable.

_Feynman Grand Prize: see http://www.foresight.org/GrandPrize.1.htm#requirements

_First 3D atomically precise structure built with an SPM. Plenty of labs have spelled out their

logo in 2D in atoms using an SPM, but no one has done this 3D. It’s coming.

_Commercial sorting rotor filters: sorting rotor filters able to sort any specified small molecule

from a fluid input are commercially available in most sizes. Further information is avaiable at

http://www.nanomedicine.com/NMI/3.4.2.htm

NANOTECNOLOGIAOVERVIEW AND APPLICATIONS

http://www.nanomedicine.com/NMI/3.4.2.htm


NANOTECNOLOGIA


_It’s impossible. This one seems mostly behing us, but sometimes appears. Ask them if they thing the

biological molecular machines in their body only works because they are imbued with “vital force”.

_It’s scary, so we should pretend it’s impossible. This one is alive and well in some quarters.

Acknowledge that thinking about how to present ideas to the public is important, but explain forcefully

that pretending that feasible technologies are impossible is not a good strategy. Discuss ways

of presenting the technology that are clearer, less alarming and technically accurate. Nobody is scared

of 3D printers, so use that to explain molecular manufacturing. Don’t describe molecular manufacturing

in terms of assemblers, wich are so small they can’t be seen, can’t be stopped, replicate autonomously,

and stir up primitive fears in people’s pscyches.

_It’s a century or more away. This one is still reasonably commom. Point out that advances in technology

often happen faster than expected. Discuss linear versus exponential thinking.


CONTROVERSIES


NANOTECNOLOGIA


_Nanotechnology refers only to objects that are small in size: it refers to objects of all sizes that are built with great precision --

objects of all sizes that are built with essentially every atom in the right place. A molecular computer might visibly sit on a desktop,

earning its right to be the “molecular” prefix because its many trillions of logic gates and interconnects were atomically precise in

their contruction. A mnemonic to help remember this myth: “There’s nothing small about nanotechnology”.

Myth: Main stream research is actively pursuing and funding research in molecular nanotechnology (MN). Much mainstream research

on MN happens by accident, despite the best efforts of funding agencies and most researchers to avoid this area. While a few

researchers are interested in this area, funding agencies are generally desinterested. Explicit proposals for research in molecular

nanotechnology, mechanosynthesis, assembler design, and related areas are seldom funded.

Myth: “nanotechnology” has a well-defined meaning. It doesn’t. Operationally the definition used in most grant applications or papers

is “A term that includes my research and will enhance my odds of getting a grant or being accepted for publication”. The major

distinctions are (a) those definitions applied to incremental improvments in existing research (“linear”nanotechnology) and (b) the

ability to inexpensively arrange atoms in most of the ways permitted by physical law (“exponential” nanotechnology, “molecular

nanotechnology”).


MISCONCEPTIONS


NANOTECNOLOGIA


_The National Nanotechnology Initiative’s website: http://www.nano.gov/

_Ralph Merkle’s nanotechnology web site: http://www.zyvex.com/nano/

_The Foresight Guidelines: http://www.foresight.org/guidelines/current.html


TOOLS & RESOURCES

http://www.nano.gov

http://www.zyvex.com/nano/

http://www.foresight.org/guidelines/current.html



PRACTICALNANOTECNOLOGIA


NANOTECNOLOGIA


BREAKTHROUGHS

_Smartphone inertial sensors brought MEMs into the consumer market, it will continue with

picoProjectors, then gas sensors, then health sensors.

_Energy harvesting (micro) for wireless, ubiquitous microsensors is coming soon.

_Human tissues “on-a-chip” moving towards a platform of interconnected tissues on chip (called

human-body on a chip) for drug testing.

_Dissolvable MEMS are an exciting research result - will it become real?

_DNA Origami drug delivery is another exciting research result - will it spur DNA Origami into

useful nanomachines?



NANOTECNOLOGIA


_Sensors liSer the earth

_Nanomaterials are not proven to be safe, there is much unknown about them


CONTROVERSIES


NANOTECNOLOGIA


_Nanotechnology is a trillion dollar industry. Please be aware of the small value

of nanotechnology content in products being touted as full value.


MISCONCEPTIONS


NANOTECNOLOGIA


_More than Moore – www.itrs.net/Links/2011ITRS/2011Chapters/2011MEMS.pdf

_MEMS Markets, Yole - www.i-micronews.com

_MEMS Markets, IHS - www.isuppli.com/MEMS-and-Sensors/Pages/Headlines.aspx

_Tissues on chip, human body on a chip –

_wyss.harvard.edu/viewpressrelease/62/wyss-ins2tutes-lungonachip-named- finalist-for-2011-index-design-for-life-

award-

_wyss.harvard.edu/viewpressrelease/80/harvards-wyss-ins2tute-creates-living- human-gutonachip

_web.mit.edu/newsoffice/2012/human-body-on-a-chip-research- funding-0724.html

_Tricorder X-Prize –

_www.qualcommtricorderxprize.org/compe22on-details/overview

_Nanomaterials Databases – – nano.taenk.dk

– www.nanotechproject.org

_DNA Origami at Wyss Ins2tute at Harvard - hSp://wyss.harvard.edu/viewpage/199


TOOLS & RESOURCES

http://www.itrs.net/Links/2011ITRS/2011Chapters/2011MEMS.pdf

http://www.i-micronews.com

http://www.isuppli.com/MEMS-and-Sensors/Pages/Headlines.aspx

http://web.mit.edu/newsoffice/2012/human-body-on-a-chip-research-

http://www.qualcommtricorderxprize.org/compe22on-details/overview

http://www.nanotechproject.org

DIGITAL BIOLOGY



Digital Biology

DIGITAL BIOLOGY


Digital Biology

DIGITAL BIOLOGY


Digital Biology

DIGITAL BIOLOGY


Digital Biology

DIGITAL BIOLOGY


Digital Biology

DIGITAL BIOLOGY - PROTHEUS


Digital Biology

DIGITAL BIOLOGY

Cada doença é rara porque depende de como cada ser humano é - DNA. Saber nosso DNA é essencial. É o conceito de segmentação da saúde. Supercenterian Research Study


Digital Biology

DIGITAL BIOLOGY - DNA 2.0

Alimentos com remédios


Digital Biology

DIGITAL BIOLOGY - Impressora de DNA


Digital Biology

DIGITAL BIOLOGY - PROTHEUS


Digital Biology

DIGITAL BIOLOGY - Impressora de DNA


Digital Biology


Com uma impressora a baixo custo, todos os valores caem em poucos anos. Será possível construir seres humanos.


Digital Biology

DIGITAL BIOLOGY - BIOPRINT


Digital Biology



DIGITAL BIOLOGYOVERVIEW AND APPLICATIONS



_Exponentially cheaper DNA sequencing costs are a reality, bringing the cost of a single human genome down from US$1B to US$5K within 15 years. _Expect DNA sequencing to continue with a 5x - 10x improvement per year. _The informatics cost of storing and analyzing, and interpreting a genome is now the majority of the marginal cost. _Advances in informatics (particularly in systems biology, pathways analysis, and visualization) will be necessary to keep this field moving forward at asteady clip. _By 2020, expect the marginal cost of sequencing a human genome to be about US 1 cent. _The democratization of biotechnology tools and techniques is a powerful force, putting more capabilities in more hands. _The future of industry looks like a micropub. Genetically engineered micro-organisms will be responsible for a progressively greater proportion of materials processing, manufacturing, drug production, and energy systems.

BREAKTHROUGHS



_Will people believe your gene map is your fate map? Will the philosophy of gene2c determinism

(The "GATACA" scenario) limit personal freedoms?

_Should genes be patented? The ACLU v. Myriad Corp. case is heading toward the US Supreme Court right now, and will

likely cast a long shadow in the industry to come. Ask your classmate, Harrison Dillon.

_Do you own your own genes? As a person, or an ethnic group? Who owns the genes in a geographical boundary?

Can non-first-world countries create wealth from their biodiversity? What does it mean to own a gene?

_Do you have the right to privacy for your genetic information? Can governments, employers, medical establishments,

family members access your genetic information?

_Are you entitled to view your own gentic information? Some bioethicists think not -- they worry both that learning too

much about genetic risks will cause unwarranted anxiety and that the economic justification is not currently there (that you

don't get enough "bang for your buck"). Conventional bioethical wisdom is that patients and the general public have no

need for genetic info.

_Is the genomic sequencing industry viable? It's still a small, mostly research-use market, doctors don't have a handle on

making use of the data, the regulatory environment makes planning hard, and the flagship companies have had a few bad

quarters recently.

CONTROVERSIES



_No one seriously talksabout "junkDNA" anymore. Only 1% of your DNA is in genes. Genes code for proteins. The rest of your DNA (formerly known as "junk DNA") is highly repetitive, but is largely responsible for gene regulation -- determining which genes are turned on in what tissues, under what conditions, and how many copies of a given gene are made.

_Getting your 23andMe data is not the same as geting your genome sequenced. Call it a "genome scan" versus a "genome sequence". 23andMe only scans about 1.2 million bases out of around 3.2 billion total. These 1.2M are the bases we know the most about for now.

_The "$1000genome" (or any other price people bandy about) is probably not the retail price, but rather the cost of chemical reagents and consumables to do a human genome sequence. It doesn't count how much it costs to buy capital equipment, pay people to run it, market, support, admin, etc. It especially doesn't count how much it costs to *interpret* that data; the phrase "$1,000 sequence, $1,000,000 interpretation" is quoted a lot.

_Epigenetics is really not all that practically important. Only a few diseases have been found to have an epigenetic basis, and the tools of gene expression are cheaper and easier ways to detect epigenetic changes in the genome.

MISCONCEPTIONS

Cartoon Guide to Genetics, Gonick & Wheelis Here is a Human Being, Misha Angrit The $1000 Genome, Kevin Davies Biopunk, Marcus Wohlsen A Hacker’s Guide to Biology, Raymond McCauley, Forthcoming...

GROUPS TO WATCH:

Genomes Unzipped Genomics Law Report Quantified Seld DIYbio BioCurious

COMPANIES TO WATCH:

Illumina Complete Genomics Ion Torrent / Life Technologies Oxford Nanopore Halcyon Molecular DNAnexus Station X Personalis NuMedii Genomic Health iKaryos Verinata ImmunePath Synthetic Genomics Amyris


TOOLS & RESOURCES


SEGURANÇA

EDUARDO BARBATOSINGULARITY UNIVERSITY EDUARDO BARBATOSINGULARITY UNIVERSITY

PRIVACY PRIVACY

1 MILHÃO DE PESSOAS ROUBADAS SIMULTANEMENTE ATRAVÉS DA PLATAFORMA PLAYSTATION

600 PERFIS DO FACEBOOK HACKEADOS POR ANO

CRIMEWARE + CRIMESOURCING


PRIVACY PRIVACY


PRIVACY PRIVACY

CRIMEWARE + CRIMESOURCING


APPS MACONHA

PRIVACY


APPS MACONHA

PRIVACY


PRIVACY PRIVACY -


PRIVACY PRIVACY - Flashrobbers


PRIVACY PRIVACY -


PRIVACY PRIVACY

+


ROBÓTICA ROBOT

APRENDIZADO PRINCIPAL

http://www.continuumfashion.com/shoes.php

http://www.behance.net/gallery/INSTANT-SHOE/7971655

http://sloanreview.mit.edu/article/with-3-d-printing-the-shoe-really-fits/?

utm_source=feedburner&utm_medium=feed&utm_campaign=Feed%3A+mitsmr+%28MIT+Sloan+Management

+Review%29

http://www.continuumfashion.com/shoes.php

http://www.behance.net/gallery/INSTANT-SHOE/7971655

http://sloanreview.mit.edu/article/with-3-d-printing-the-shoe-really-fits/?utm_source=feedburner&utm_medium=feed&utm_campaign=Feed%3A+mitsmr+%28MIT+Sloan+Management+Review%29

Business

SIngularity University - Palestra Eduardo Barbato