103 103824*

103 103

*

103

*

*

(1/3)

6565(ex103-38=65)1.2.

IC50-6450-646661.2.NIIS

(2/3)

1.2.1-61031-6

(3/3)*

*

103*/// (HnNn)63(35M)0.25mL3(36M)0.5mL

Recommended composition of influenza virus vaccines for use in the 2014-2015 northern hemisphere influenza season A/California/7/2009 (H1N1)pdm09-like virusA/Texas/50/2012 (H3N2)-like virusB/Massachusetts/2/2012-like virus

*3 4

*AGRIPPAL S1(0.5mL)

2-8

1/4-1/3

*

()58*

0.5mL 108.85/0.25mL 117/

*

(1/3) 3(101)2(102)916()*

(2/3) *

(3/3)

22-82

1 2 34

,+9

6(NIIS)707*

IVIShttps://ivis.cdc.gov.tw/INFVCWEB/Login.aspx

*()() (3643e-mail:cdcivis@cdc.gov.tw)

65()-65)6

65 101

AGRIPPAL S1

*

/ 1.2.:VICP3.4.1.2.: 3.4.

ADR

TFDA

/

1.2.VICP

1.2.

*

65*

*

10310-1110310-12()

*

(80%)10/1-10/311.811/1-11/301.512/1-12/311.2(20%)(8)(3)(4)(2)(3)

*

*1021-19%10/311.811/301.512/1-12/311.2

ABCDEFGC+G(C+G)*26 /60-64 C= B/A10/1-10/30(D)11/1-11/31 (E )12/1-12/31(F) G=(D*1.8+E*1.5+F*1.2)/ (D_+E_+F_)(C+G) (C+G)*261370,146 143,151 3,892 8,270 41.96%128,440 14,671 3,606 22.05%64.01%16.6 2179,949 87,895 3,956 4,959 53.80%80,117 10,956 2,753 14.04%67.84%17.6 373,557 34,433 1,000 817 49.28%31,360 3,424 901 5.37%54.65%14.2 4111,098 48,116 1,423 769 45.28%41,716 5,463 1,505 7.29%52.57%13.7 530,734 13,521 693 411 47.59%12,193 1,746 360 2.14%49.73%12.9 Total2,671,274 1,124,992 42,405 32,072 44.90%1,010,967 123,235 33,461

*

1./*10042./*100%4103.10.018201.1-/22./*1001103.10.013/*100%4211 103.10.014103{1-[(+)/]}*100% (2)103.10.01104.2.282() (3)103.12.203

*

102H7N9() 103103511031231103

*

WHOH1N1H1N1()

*

WHO()2.7ACIP*

*

***

98-101 S(:: )98: 4/87599: 5/705100: 25/1132101: 85/1241102: 46

**