טיפול תרופתי - פרקינסון

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Text of טיפול תרופתי - פרקינסון

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MAO COMT

.1 .2 .3 .4 .5 .6

, . . basal ganglia . %08 . .

-. Levodopa , , - - .- Levodopa . levodpa - , -Carbidopa .benserazide .

( 8 Dopicar (carbidopa 25 mg / levodopa 250 mg . (Levopar plus (levodopa 100/200 mg / benserazide 25/50 mg

. , ( -(. - . (domperidone (motilium , , , . . , .

. , . end-of dose , . on-off levodopa, .

. bromocriptine, ropinirole . levodopa levodopa , . off levodopa .

40 " Parilac, Parlodel (bromocriptine( 2.5 ." 4. "Cabaser (carbegolide( 1, 2 1.0. "Pergolide 0.05, 0.25 5. "Requip (ropinorole( 0.25, 0.5, 1, 2

Apomorphine . - off .levodopa 01 Apo-go"/" S.C

Amantadine , - . - , . 001 A-parkin, Paritrel, PK-Merz" , .

MAO

-- B . Selegiline .MAO B , levodopa . selegiline, , levodop levodopa . 5 Jumex", 01 . "

COMT

--- . . entacapone levodopa . 002 Comtan" . . levodopa

, , . , . , , , , / . 2 ( Dekinet (biperidine", 4. 5 ( Kemadrin (procyclidine", 03. "