Answers1Ondansetron HCL is used for :a- Hypertensionb- Angina pectorisc- Prophylaxis of migrained- Anti-emeticIt is used as anti-emetic with patients receiving cytotoxics dueto its serotonin antagonism.Ondansetron is [ Zofran 2 , 4 mg. Tab & Amp. ]2All These are side effects of Chloramphenicol except :a- Irreversible a plastic anemiab- optic neuritisc- peripheral neuritisd- iron deficiency anemia3Ticlopidine is used for :a- Anticoagulantb- Antibioticc- anticholinergicd- Antiplatelets4All these drugs are fibrinolytic except :a- Dipyridamoleb- Steptokinasec- urikinase5All These drugs cause anti-metabolic effect except :a- Methotrexateb- FlurouracilC- Cytabrind- Azothioprinee- Cyclophosphamide6All These drugs can be used for Parkinsonism except :a- Selgitine HCLb- Carbidopac- Pergolided- Nedocromil Sod.7all These cases not cure with thiazides except :a- Hypernatrimiab- hyperglycemiac- Hypokalaemiad- hyperuricaemia8Cardiac arrest could be managed by the following except :a- Ephedrineb- Ledocainec- Propranolold- Normal saline9Insulin which can be given I.V. is :a- Regular typeb- 30/70 typec- NPH typed- Non of the above10Drug is used for Leishmania :a- Sod. Stiboglyconateb- Sod. Cromoglyconatec- Mebendazole11All These drugs are anti-bacterial except :a- Zalcitabineb-Lomefloxacinc- Cefprazone12All These are natural Estrogens except :a- Mestronolb- Oestronec- Oestriold- Oestradiol13Co-Trimethoxazole contains ;Trimethopirm + Sulphmethoxazole14Which one of the following has vasodilator effect :a- Nicotineb- Cholestyraminc- urikinased- Vit. A15One of the following is not from Quinolone group :a- Nalidixic acidb- Quininec- Eoxacind- Norfloxacin16One of the following is not for Epilepsy :a- Clorizepamb- Phenytoinc- Primidoned- Imipramine17All of these can be used for Leprosy except :a- Dapsonb- Rifampcinc- Clofazinined- INH18Sumatriptan is used for :a- Hypertensionb- Treatment of migrainec- Angina Pectorisd- Control of Epilepsy19Which one of the following is enzyme inducer :a- Rifampcinb- Cimetidinec- Chloramphenicold- Vit. C20All of the following for prophylaxis of asthma except :a- Ketotifenb- Nedocromil Sod.c- Sod. Cromoglycated- Salbutamol21All of the following is NSAH [ non sedating antihistamine ] except :a- Loratidineb- Cetrizinec- Astemizold- Azotodin22All of the following are controlled drugs except :a- Rivotrilb- Epanutinc- Sresolidd- Diazepam23All These drugs are anti-viral except :a- Amantadineb- Zidovudinec- Acyclovird- Aluerin [ anti-spasmodic ]24Which one of the symptoms does not occur with morphine :a- Diarrheab- Respiratory depressionc- Constipationd- Vomiting25Which one of these drugs is not used for acute pain :a- Naproxenb- Colchicinec- Codeined- Prednisolone26Which one of these drugs is drug of choice for Myxodema[ Hypothyrodism ]a- Carbimazoleb- iodinec- thyroxin sod.d- propyl thiouracil27Benzyl peroxide is a local treatment for Acne Vulgaris28Vit. A daily dose is 30,000 - 50,000 IU for the correction ofdeficiency and for therapy from 100,000 - 200,000 IU / daily29The drug of choice for the treatment of amoebae :a- Chloramphenicolb- Tetracyclinec- Gentamycind- Metronidazole30To prevent more absorption of the toxic drug we use :a- Waterb- Salt Sol.c- Salined- Charcoal31Hepatitis Vaccine dose is :a- Once / yearb- Twice / Yearc- Three times / Year32Which one is OTC drug :a- Simple analgesicb- Warfarinc- Ciprofloxacin33Anti-coagulant effect of Warfarin is decreased by :a- Rifampcinb- Aspirinc- Vit. Kd- Verapamil34One of the following is given once dailya- Amorphous Insulinb- Protamine Zinc Insulinc- Neutral insulind- Regular Insulin35The steady state conc. Of the drug in the plasma depends on :a- Direct proportion to the rate of administrationb- Indirect proportion to the rate of administrationc- Indirect proportion to the rate of eliminationd- Direct proportion to the rate of elimination36All these are Anti-Coagulants except :a- Warfarinb- Ancordc- Heparind- Dipyridamol37All these are Anti-Platelets except :a- Dipyridamolb- Aspirinc- Streptokinased- Presantine- Ticlopidine38Ferrograde is :a- Ferrous Sulphateb- Ferrous Citratec- Ferrous gluconated- Ferrous Fumarate39Procainamide is :a- Ca channel blockerb- Nifedipinec- Lisinoprild- Qunidine40What is the mechanism of action of Vit. K ?Vit. K has an essential role in the synthesis of coagulationfactors by hepatic cells.41Thiazide diuretics cause all the following except :a- Hypokalamiab- Hypercalcemiac- Hyperuricamiad- Hyponatrimiae- Hyperglycemiaf- Hypernatremia42Treatment with anti-arrhythmic drug depends on except :a- Type of medicationb- Period of medicationc- Patient sex43Elimination of Digoxin is mainly by :a- Kidneyb- Liverc- Bothd- None of the above44Dobutamine is given I.V. because :a- It is not stable in the gastric PHb- It is needed in large quantities in case of oral routec- It is eliminated very quickly45Amilorid as trimetren causes :a- CNS disturbancesb- Hyperkalamiac- Hypokalamiad- Not affect K [ Potassium ]46What is the most drug can cause damage if it is given OTC ?a- Captoprilb- Warfarinc- Chlorothiazided- Rifampcin47Drug physical dependence is as same as drug abusea- Trueb- false48Mention two Thiazide diuretics ?1- Chlorothiazide2- Hydrochlorothiazide49What is the difference between QID & Q6H ?QID = 4 times / dayQ6H = every after 6 hours50What is the difference between the following anti-fungal ?Miconazole = local & systemicAmphotercin = parenteral onlyGriseofulvin = oral51Give the indication of the following drugs :1- Gimfibrazolefor hyperlipidaemia2- Cisapridefor gastro-oesophegyal reflux3- FluoxetinSSRI [ selective serotonin reuptake inh.]( Antidepressant )4- Carbimazolefor hyperthyrodism5- ImipramineTricyclic anti-depressant6- Ipratropium Br.Anti muscarinic as broncho-dilator52All are anti-metabolic except :a- Methotrexateb- Flurouracilc- Cytabrind- Azothiopine- Cyclophosphamide53Cefaclor is :a- Ist, Generation Cephalosporinb- 2nd, generation Cephalosporinc- 3rd, generation Cephalosporind- None of the above54Which Aminoglycoside antibiotic can be taken orally ?a- Gentamycinb- Neomycinc- Amikacind- Tobramycin55Teicoplanin antibiotic has similar effect on Gram positive as :a- Vancomycinb- Jamicacinc- Gentamycind- Kanamycin56Which one is not Tetracycline ?a- Minocyclineb- Demeclocyclinec- Doxycyclined- Clindamycin57Which one is not Ca channel blocker ?a- Verapamilb- Deltiazemc- Amlodipined- Cinnarzine58Mesalazine is used for the treatment & maintenance of remissionof Ulcerative Colitis59Mention 4 lipid soluble vitamins ?Vit. A, D ,E & K60Imipenam [ Carbapenam ]It is the first Thiemamycin Beta - Lactam anti-biotic61All These medications are used in treating T.B. except :a- Cyclosporinb- INHc- Cycloserind- Rifampcin62All These drugs are anti-cholinergic except :a- Iprotropiumb- Atropine Sulphatec- Benzatropine Methylated- Dobutamin63All Of These are antibiotics except :a- Zalcitabinb- Cefaprozilc- loefloxacind- Cefopodoxin64There is one drug is used for HIV :a- Zalcitabinb- Kinasterdinc- Cefaprozild- Enoxacin65Which one is Suprax ?a- Cefiximeb- Itraconazole66Which one is Sporanox ?a- Cefiximeb- Itraconazole67All of These can be used in treating leprosy except :a- Dapsonb- Rifampcinc- Clofazimined- INH68One of these is not like the others :a-TimololNon - selectiveb- AcebutalolSelective Beta Blockerc- LabetololNon - selectived- BetaxololNon - selective69Which is not Aminoglycoside ?a- Netilimicinb- Tobramycinc- Kanamycind- Lymecyclin70Betahistine HCLa- For Mieniere diseaseb- Antihistaminec- Analgesicd- a & b71Which one is not 5HT3 antagonist ?a- Tropisetronb- Ondansetronc- Domperidone [ Motilium ]d- Granisetron72Which is not oral anti-coagulant ?a- Warfarinb- Enoxaprinec- Phenidioned- Nicoumolone73Which is correct ? Diazepama- Can cause muscle spasmb- Is taken I.M. onlyc- Is derivative from Morphined- Is not used for long term74Maximum dose of Paracetamol is 4 Gm / day75The duration of treatment of T.B. by CTC is :[ CTC is Tuberculosis Committee Thoracic Society ]a- One weekb- Two monthsc- One monthd- 6 months76Metoclopramide is a dopamine antagonistacts centrally by blocking Vomiting Center [ V.C. ] andperipherally acts on the Chemo-Receptor Trigger Zone [ CTZ ]to be used as anti-emetic.77Which one is contra-indicated in pregnancy :a- Sucralfateb- Ethambutolc- Chlorphenramined- Ciprofloxacin78What is the definition of Bioavailability of the drug ?Is the quantity of the active constituent of the drugabsorbed by the blood through the intestine or any otherroute in a certain period of time .OR : It is the conc. of the drug in the blood in a certainperiod of time79Give an ex. Of a drug induce Hepatotoxicity ?1- Paracetamol2- Ketoconazol3- Rifampcin4- Quinolones80Give an ex. Of a drug induce Nephrotoxicity ?Aminoglycosides as Gentamycin81Give the anti-dote for each of the following :HeparinProtamine SulphateParacetamolAcetyl cystineWarfarinVit. KMorphineNaloxone82What is the generic name of Vit. B 12 ?Cyanocobolamine83Zidovudine is used for HIV84What is the meaning of poor patient compliance ?The patient did not take the medication properly [ not properdose, not proper time ] may be due to the dose regimen is noteasy or the dose is high, or the side effects is clear85Fluxotine is :Prozacis selective serotonin re-uptake inhibitor86Omeprazole isLosecis a proton pump inhibitor87Mention two diseases cause Edema ?1- Renal Failure2- Congestive Heart failure88Give examples of drug - drug interactions ?1- WarfarinAspirin2- InsulinB-Blockers3- HeparinAspirin & Ampicillin4- WarfarinVit. K5- WarfarinPhenobarbital6- SpironolactoneDigoxin7- ACEIPot. Sparing diuretics89Generic name of :Vit. B1ThiamineVit. B2RiboflavinVit. B6PyridoxinVit. B12Cyanocobolamine90All of these are the components of Calamine lotion B.P. except :a- ZnOb- calaminec- Sod. Citrated- Bentonitee- Sod. Sulphate91Terbinafine is used topically for :a- Eczemab- Candidac- Fungal infections92Which one is not contra-indicated in pregnancy ?a- Captoprilb- Enalprilc- Lisinoprild- Methyldopa93PCP [ Pneumocystis Corini Pneumonia ]a- Virusb- Bacteriac- Parasited- Mycobacterum94Which of the following is not antibiotic ?a- Erythromycinb- Cefprozilc- Ceprodoxind- Finasteride95Which one is used for Benign Prostatic Hyperplasia [ BPHP ]a- Flumazenilb- Cefprozilc- Mivacurimd- Finasteride96All of these are third generation Cephalosporin except :a- Cefiximeb- Cefopodoximec- Ceftriaxoned- Cefotaxime97Which of the following is not mucolytic ?a- Bromohexinb- Carbocistenec- Ambroxold- guaphenesine- Dextromethorphan98Which one is anti-platelet ?a- Ticlopidineb- Desfluronc- Aldesleukind- Atovaquon99All of these anti-neoplastic except :a- Aldesleukinb- Teniposidec- Pentostatind- Amlodipine100Which is not Benzodiazepine ?a- Temazepamb- Nitrozepamc- Loprazolamd- Clozapine101Potassium supplement must not be given with Triametren1- False2- True102Misoprostol inhibit gastric acid by blocking the hydrogen potassiumadenosine triphosphate enzyme system of gastric cell[ Misoprostol is Cytotic ]1- False2- True103MMR vaccine is Measles - Mumps - Rubella vaccine104Oral re-hydrate solution is one of the following :a- Sod. Citrate - Pot. Chloride - Glucoseb- Sod. Citrate - Pot. Chloride - Sod. Chloridec- Sod. Chloride - Pot. Citrate - Sod. Citrate - glucosed- Sod. Chloride - Pot. Chloride - NaHCO3 - Citric acid105Gemfibrazilea- Increase HDL & Triglyceridesb- Increase HDL & decrease Triglyceridesc- Decrease HDL & LDLd- Increase LDL & Triglycerides.106Nitroprusside Sod. Is :a- Potent vasodilatorb- potent diureticc- potent vasoconstrictord- Anti-arrhythmic agent.1074 drugs need monitor for their serum level1- Amikacin3- Warfarin2- Theophyllin4- Digoxin108For Fluxacillin, all these statments are wrong except :a- It is activated by Penicillinase enzymeb- It is taken by oral route onlyc- It is base stabled- It is better absorbed than Cloxacilin109What are the instruction for patient taken MetamucilOr any other bulk foaming laxative as Bran, methyl Cellulose &Psyllum : The adequate fluid intake should be maintained toavoid intestinal obstruction110CytotecIs used for gastric & duodenal ulcer. It is contra-indicated inpregnancy.111Mention two drugs from HMG - COA- reductase inhibitorsSimvastatin - Provastatin - Fluvastatin112HMG-COA-Reductase Inhibitor is[ 3-hydroxy. 3- methyl Glutoryl COA Reductase inhibitor ]113Source of Human Insulin is E-Coli by :Recombinant DNA Technology114Zinnat contains :Cefuroxime115Thiabendazole is one of Thiazides diuretics1- False2- TrueN.B. Thiabendazole is anthelmintic116Praziquantil is :a- Cause loss of intracellular calcium of wormsb- Used for malariac- Biltracid is the trade named- a & c117Nitrofurantoin is indicated for :a- Viral infectionb- GIT Infectionc- Urinary tract infection [ UTI ]d- URI118Vit. Ka- Increase formation of clotting factorb- Increase conversion of Vit. K to the active formc- Prevent conversion of Vit. K back to the active formd- Non of the above119Quinidine Sulphate is :a- Anti-arrhythmic agentb- Anti-malarial agentc- Anti-hypertensive agentd- a & c120ACE stands for :a- Converting Ag11 to vasoconstrictor Ag1b- Converting Ag1 to vasoconstrictor Ag11c- Converting Ag1 to vasodilator Ag11d- Converting Ag11 to vasodilator Ag1121One of these side effects not occur with Thiazide diureticsa- Hypernatraemiab- Hypoglycemiac- Hypokalamiad- Hyperuricamia122Ipeca is emetic agent which induce emesis through :a- Stimulation of the stomachb- Stimulation of the CTZc- a & bd- Inhibition of the stomach through CNS123Theophyllin isa- Bronchdilatorb- B2 agonistc- Cause Bradycardiad- All of the above124Schedule of immunization for HBV is :a- Single doseb- Two dosesc- Three dosesd- Five doses125Itraconazolis antifungal126Treatment of anaphylactic reaction is initiated by immediate :a- Hydrocortisoneb- Cimetidinec- Human albumind- Epinephrine127Introduction of emesis is not indicated in the following except :a- Caustic substance ingestionb- CNSc- Seizuresd- paracetamol poisoning128all of these are anions except :a- Phosphateb-Acetatec- Sodiumd- Chloride129Astemizoleis long acting non sedating anti-histamine130Triazole isa- Antifungalb- Trade name of clotrimazolec- Trade name of amphotercin Bd- Nystatin131With Minoxidil, all these parameters should be monitored except :a- Urine flow rateb- B.P.c- Pulse rated- Body weight132Aspirin is recommended with one of the following :a- Anti-coagulantb- Chicken boxc- Influenza symptomsd- Dys-menorrhoea133Which is not true with Tetracyclinea- Broad spectrum bacteriostaticb- Broad spectrum bactericidalc- Inhibit protein synthesisd- Used for acne134Give 2 indications for allopurinol1- prophylaxis of Gout2- Treatment of uric acid & Ca Oxalate renal stones135Give an ex. Of non sedating anti-histaminesLoratidine - Cetrizine- Terfenadine136Famotidine is H2 antagonist used for :Treatment of gastric & duodenal ulcers137What are the effects of Captopril1- Decrease conversion of Ag1 to Ag112- Effective hypotensive when others are contra-indicated[ B blockers & diuretics ]138Type 2 Diabetics is characterized by :a- Lack of response to Insulinb- Lack of response to sulphonylureac- Respond to dietary therapy aloned- Slowly increasing sulphonylurea requirement139Give 2 side effects of Aminoglycosides ?Ototoxicity - Nephrotoxicity140Mention 2 quinolonesCiprofloxacinNorfloxacin141Give 3 drugs as Pot. Sparing diureticsTrimetren - Spironolactone - Amilorid142Acetazolamide is a diuretic used for Glaucoma by inhibition ofcarbonic anhydrase enz. This reduce the carbonate in the aqueoushumor leads to reduction of I.O.P.143Which one reduces the metabolism of other drugs in the liver :a- RifampcinB- Vit. Cc- Cimetidined- Metronidazole144All of these can be dispensed without prescription except :a- Aspirinb- Maaloxc- Bisacodyld- Tegretol145Simvastatin is used for hypolipidemic action146Acetohexamide is hypoglycemic147List the trade name of the following :PindololViskenBaclofenLioresalOmeprazolLosec148What is the meaning of each of the following :POMPrescription Only MedicineBIDTwice DailyECGElectro Cardio GramG.6.PDGlucose 6 phosphate dehydrogenaseBPCBritish Pharmacopial Codex149Which of these is Pro-druga- Ampicillinb- Erythromycinc- Pivampicillind-All of the above150500 ml Normal saline 0.9 % contains 4.5 gm. NACL151Mention 3 ACEICaptopril - Enalpril - Cilazapril152Levodopa with Cardiodopa for the treatment of Parkinsonism153Specific Serotonin reuptake inhibitor are used as :a- Antihistaminicb- Antidepressantc- Antihypertensived- Antiemetic154Which of these has no vasodilator effect :a- Methyl dopab- Hydralazinec- Enalprild- Prazocin155Enalpril is the prodrug of :Enalprilate156Mention 3 drugs contraindicated in pregnancy :1NSAI2Co-trimoxol3Antiepileptic157List 3 drugs used to treat T.B. :1INH [ Isoniazide ]2Rifampcin3Ethambutol158Calcipotriol is indicated for :a- Psoriasisb- Hypertensionc- Calcium supplementd- Acne159List 8 side effects of Corticosteroids :1Water & sod. Retention2Cushing syndrome3Gastric ulcer4Hypertension5Pot. Loss6DM [ diabetes mellitus ]7Glaucoma8Osteoporosis160Maximum dose of Captopril is 150 mg / day161Amantadine is used for all of the following except :a- Antiviralb- For influenza Ac- Anti-parkinsonismd- For influenza B162All are viral infections except :a- Hepatitis Bb- Influenzac- Herpes Zosterd- Rikettsia163At the cardiac arrest [ shock ] . The drug of choice is :a- Epinephrineb- Propranololc- Hydrocortisoned- Saline sol.164Give ae example of cardio selective B blocker ?a- Atenololb- Bisoprololc- Esmolold- Betaxolole- Metoprololf- Acebutolol165Drugs to pass B.B.B. should be :a- Unionized hydrophilicb- Ionized hydrophilicc- Unionized lipophilicd- Ionized lipophilic166All of these are anti-parkinsonism except :a- Amantadinee- Lysurideb- Apomorphinef- Pergolidec- Bromocriptineg- Levodopad- Primidoneh- Selegiline167All of these are anti-metabolite [ cytotoxic ] except :a- Methotrexated- Azothioprinb- Cylarabine- Mercaptopurinec- Cyclophosphamidef- Flurouracil168All of these are antichlonergic except :a- Atropine sulphated- Iprotropium bromideb- Hydroatropinee- Butrepium bromidec- Mebeverine169All of these are corticosteroids except :a- Ondansetrond- Beclomethasoneb- Prednisolonee- Dexamethazonec- Triamcinolonef- Methyl prednisolone170When newly married do not want child. How to arrangea- Arrange contraception.b- Send wife to the family doctorc- Send the wife to her mother171Side effects of Insulin ?1Local reaction [ urticaria ]2Hypoglycemia3Fat dystrophy at site of injection172One of the following is the main side effect of insulin :a- Hypoglycemiab- Fluid retentionc- Hyperglycemiad- All of the above173The only aminoglycoside can be taken orally is :Neomycin sulphate174Chloramphenicol affect liver inhibitory enzyme. Soa- Decrease metabolism & increase responseb- Decrease metabolism & decrease responsec- Increase metabolism & increase responsed- Increase metabolism & decrease response175OTC simple analgesic is paracetamol176Enteric coated taba- Pass the stomach & release in the intestineb- Pass the stomach & intestinec- Release in the stomach177All of these are true for Levodopa except :a- precursor of dopab- Does not pass B.B.B.c- Effective in parkinsonismd- Stimulate dopamine178Morphine & Morpin are similar in addiction179Cytocin is one of the posterior pituitary hormones180The conc. Of the drug on Exp. Date is :a- Not less than 100%b- Not less than 90%c- From 90-110%d- Non of the above181If you have prescription contains Inderal and the patient iswheezing. What is your advice ?Call the doctor182Bioavailability means :a- Rateb- Extentc- Rate & extentd- Non of the above183Pharmacokinetics means :a- Effect of the body on the drugb- Drug - receptor reactionc- Non of the above184Surfactant not used orallya- Tweenb- Sponc- Na lauryl sulphated- B & C185Type 1 Diabetes. advise to use :a- InsulinB- Glibneclamidec- a & bc- Non of the above.186Type 11 Diabetes. advise to use :a- Diet controlb- Insulinc- Sulphonyl uread- All of the above187One of the following is the main side effect of insulin :a- Hyperglycemiab- Hypoglycemiac- Fluid retentionC- All of the above188Pentobarbital differs from Phenobarbital in :a- Longerb- FasterC- Not use very muchd- a & b189Morphine & morpin are similar in :a- Miosisb- AddictionC- Analgesicd- All of the above190Theophyllin dose in children.a- Increased metabolism & dose must be increased .b- Decreased metabolism & dose must be increased .c- Decreased metabolism & dose must be decreased .191Biotransformationa- More lipid solubleb- Less lipid soluble.192Phenylephrine is used for :a- Decongestantb- For runny nosec- Sympathomimetics.d- All of the above.193Oxytocin produces all the following except :a- Progestron releaseb- Uterine stimulationc- Labor inductiond- Mammalian glands stimulation194Binding to the plasma protein , means :a- Increase half lifeb- Decrease half life.195New & best therapy for peptic ulcer is :a- Antacid + H2 antagonist.b- Use more than one H2 antagonist.c- Four medicines including antibiotic.196In case of Osteoarthritis & peptic ulcer of elderly patients use :a- Paracetamolb- Strong NSAIc- Aspirin197Give names of drugs that change the color of urine ?1Nitrofurantoin2Phenazopyridin3Rifampcin198The drug of choice for Febril Convulsion in children is :Diazepam 250 microgram / kg.199Cyproteron [ Androcur ] is used for :Increasing the sexual abilities.200Immunocompetent means ?Control resistant to infections.201Immunocompromised means ?Low resistant to infections.202Which of the following is not cardio-specific B blocker ?a- Atenololb- Acebutololc- Satolold- Labetolol203Controled released drug delivery depends on :a- Body fluid interactionb- Enzymatic reactionsc- Ready programmed & no influece of the body fluidd- Stomach PH.204The conc. Of the drug on exp. Date is :a- Not less than 100%b- Not less than 90%c- From 90 - 110%d- Not of the above205Type 11 Diabetes. Advise to use :a- Diet control.b- Insulinc- Sulphonyl Urea.d- All of the above.206All of these are antichlonergics except :a- Atropine Sulphateb- Hydro-atropine.c- Mebeverine.d- Iprotropium Bromide.e- Butrepium Bromide.207Pharmacokinetics means :a-Effect of the body on the drug.b- Drug - Receptor reactionc- Non of the above.208Specific Serotonin reuptake inhibitors are used as :a- Anti-histaminicb- Anti-depressantc- Anti-hypertensived- Anti-emetic209Type 1 Diabetes. Advise to use :a- Insulinb- Glibneclamidec- a & bd- Non of the above.210Biotransformationa- More lipid solubleb- Less lipid soluble211Pentobarbital differs from Phenobarbital in :a- Longerb- Fasterc- Not use very muchd- a & b212Which one of these can not be used in pain crisis :a- Morphineb- Naproxinec- Codeined- Colchicin [ used mainly in gout pain ]213All of the following are Ca ++ channel blockers except :a- Mesalamineb- Verapamilc- Cinnarzined- Amlodipine214One of the following is not used for Parkinson disease :a- Pergolideb- Seleglinec- Amantadined- Disulfiram215All the following are ACE inhibitors except :a- Captoprilb- Ramiprilc- Lisinoprild- Isradipine216Quinidine Sulphate Is :a- Anti-arrhythmicb- Anti-malarialc- Anti-hypertensived- a & b217All the following are used as Anti-tussive except :a- Guaifenesinb- Dextromethorphanec- Codeine Phosphated- Morphine Hydrochloride218Nitrous Oxide is used in anaesthesia because :a- It is non explosive & non inflammableb- It induces rapid induction & rapid recoveryc- It is potent muscle relaxantd- All of the above219All of the following have GIT upset except :a- Phenytoinb- Phenobarbitonc- Ethosux - Pn 7 ded- Benzodiazepam220A patient has a prescription of Erythromycin 500 mg tablets every 6 hours.and you do not have this anti-biotic. You can phone the doctor to changeit with :a- Clarithromycinb- Amoxicillinc- Clindamycind- Ampicillin221A child of 41 degrees centigrade, when his father ask you about him,you must tell him to :a- Go to hospital which is 30 m. distance.b- Sponge by tap water and go to hospital.c- Take 1 GM. Paracetamold- Go to home.222The patient under the prescribing drug.when he comes to you , Then you must tell him :a- All the drug side effects.b- Some relatively side effects.c- Another side effects.d- Non of the above223A patient has a prescription of Enalpril + KCL,what are you ask him ?a- Any product of K do you need.b- You take any other anti-hypertensivec- You need syrup or tablets.d- Not of all224ACE inhibitors are used for the treatment of :a- Asthmab- Migrainec- Hypertensiond- All of the above225New non sedative anti-histaminics act through :a- H1 antagonistb- H2 antagonistc- Muscarinic receptorsd- B1 antagonist226All of the following are B antagonists except :a- Salbutamolb- Metoprololc- Nadolold- Atenolol227B agonist causes :a-Increasing of Oxygen consumptionb- Increasing of ectotopic effectc- Increasing of inotopic effectd- All of the above227Atropine is used as pre-anaesthetic to :a- Give skeletal muscle relaxationb- Decrease salivac- Treat the side effects of anesthesic.d- Help the sleeping effect of anaesthetic228A patient weighing 10 kilograms is given a paracetamolone teaspoon full every 4-6 hours.you should call doctor and tell him that :a- The dose is very highb- The dose must not exceed 180 mg dailyc- The dose is not sufficientd- There is no need to call the doctor.229Malignant hypothermia is usually a side effect of :a- Anaesthesiab- Azathropinc- Phenytoind- Aspirin230The common side effect of Sulphonylurea is :a- GIT upsetb- Thyrotoxosisc- Hypoglysurisd- All of the above231Vasopressine is used for the treatment of :a- Diabetes insipidusb- Diabetes mellitus type 1c- Diabetes mellitus type 2d- Anti-hypertensive232Pseudomembraneous colitis is a side effect of :a- Vancomycinb- Clindamycinc- Reserpined- INH233Phenobarbiton induces liver microsomal enzymeswhen taken with Warfarin anti-coagulant leads to :a- Increasing the activity of liver enzymesso, decreasing the activity of Warfarinb- Increasing the activity of liver enzymesso, increasing the activity of Warfarinc- Decreasing the activity of liver enzymesso, decreasing the activity of Warfarinc- Decreasing the activity of liver enzymesso, increasing the activity of Warfarin234Tetracycline, when taken with metals such as Calcium, Iron & Aluminiumfrom a chelate which is :a- Inactive & not absorbedb- Active & poorly absorbedc- Inactive & poorly absorbedd- Active & absorbed235Disulfiram is used for :a- Treatment of chronic alcohol dependenceb- Protection of liver cells from alcoholismc- Prevention of conversion of acetaldehyde to acetic acidd- All of the above236The drug transfer through the cell membrane by :a- Aqueous diffusionb- Osmotic pressurec- Lipid dissolved- Non of the above237Protein bound drugs forming a compound which is :a- Inactive while the free part is activeb- Highly active while the free part is inactivec- Less active while the free part is actived- Active while the free part is more active238The drug metabolism in the body occurs in :a- GIT & Plasmab- Gut wall during absorptionc- Gut wall during absorption & in plasma streamd- Liver , Kidney & bowel mucosa239Clonidine is used as :a- A drug that prevents the recurrence of Migraineb- Anti-hypertensive acting centrallyc- a & bd- Non of the above240Dolomol is :a- Paracetamol with analgesic & anti-inflammatoryb- Paracetamol with analgesic & without anti-inflammatoryc- Non Paracetamol with analgesic & anti-inflammatoryd- Non Paracetamol with analgesic & without anti-inflammatory241Metoclopramide gives its anti-emetic through :a- Peripheral actionb- Dopaminergic receptorsc- Muscarinic receptorsd- All of the above242Dobutamine is used as :a- Parasympathomimeticb- In cardiac surgeryc- Hypotensive agentd- All of the above243The following are the indications of Diazepam except :a- Anti-Psychoticb- Epelipsyc- Analgesicd- Hypnotic244The diuretic which is used with Captopril is :a- Aldactoneb- Ethacrynic acidc- Furosemided- Non of the above245The following drugs are used for the treatment of anxiety except :a- Propranololb- Diazepamc- Homatropined- Mebrobamate246All the following are macrolides except :a- Clarithomycinb- Roxithromycinc- Erythromycind- Clindamycin247The main use of Metronidazole is :a- Anti-amoebiasisb- Anthelminticc- Anti-bioticd- Anti-malarialALL THE BEST & SUCCESS

Questions1Ondansetron HCL is used for :a- Hypertensionb- Angina pectorisc- Prophylaxis of migrained- Anti-emeticIt is used asOndansetron is2All These are side effects of Chloramphenicol except :a- Irreversible a plastic anemiab- optic neuritisc- peripheral neuritisd- iron deficiency anemia3Ticlopidine is used for :a- Anticoagulantb- Antibioticc- anticholinergicd- Antiplatelets4All these drugs are fibrinolytic except :a- Dipyridamoleb- Steptokinasec- urikinase5All These drugs cause anti-metabolic effect except :a- Methotrexateb- FlurouracilC- Cytabrind- Azothioprine1e- Cyclophosphamide16All These drugs can be used for Parkinsonism except :a- Selgitine HCLb- Carbidopac- Pergolided- Nedocromil Sod.7all These cases not cure with thiazides except :a- Hypernatrimiab- hyperglycemiac- Hypokalaemiad- hyperuricaemia8Cardiac arrest could be managed by the following except :a- Ephedrineb- Ledocainec- Propranolold- Normal saline9Insulin which can be given I.V. is :a- Regular typeb- 30/70 typec- NPH typed- Non of the above10Drug is used for Leishmania :a- Sod. Stiboglyconateb- Sod. Cromoglyconate2c- Mebendazole211All These drugs are anti-bacterial except :a- Zalcitabineb-Lomefloxacinc- Cefprazone12All These are natural Estrogens except :a- Mestronolb- Oestronec- Oestriold- Oestradiol13Co-Trimethoxazole contains :14Which one of the following has vasodilator effect :a- Nicotineb- Cholestyraminc- urikinased- Vit. A15One of the following is not from Quinolone group :a- Nalidixic acidb- Quininec- Eoxacind- Norfloxacin16One of the following is not for Epilepsy :a- Clorizepamb- Phenytoinc- Primidone3d- Imipramine317All of these can be used for Leprosy except :a- Dapsonb- Rifampcinc- Clofazinined- INH18Sumatriptan is used for :a- Hypertensionb- Treatment of migrainec- Angina Pectorisd- Control of Epilepsy19Which one of the following is enzyme inducer :a- Rifampcinb- Cimetidinec- Chloramphenicold- Vit. C20All of the following for prophylaxis of asthma except :a- Ketotifenb- Nedocromil Sod.c- Sod. Cromoglycated- Salbutamol21All of the following is NSAH [ non sedating antihistamine ] except :a- Loratidineb- Cetrizinec- Astemizol4d- Azotodin422All of the following are controlled drugs except :a- Rivotrilb- Epanutinc- Sresolidd- Diazepam23All These drugs are anti-viral except :a- Amantadineb- Zidovudinec- Acyclovird- Aluerin [ anti-spasmodic ]24Which one of the symptoms does not occur with morphine :a- Diarrheab- Respiratory depressionc- Constipationd- Vomiting25Which one of these drugs is not used for acute pain :a- Naproxenb- Colchicinec- Codeined- Prednisolone26Which one of these drugs is drug of choice for Myxodema[ Hypothyrodism ]a- Carbimazoleb- iodinec- thyroxin sod.5d- propyl thiouracil527Benzyl peroxide is a local treatment for28Vit. A daily dose is29The drug of choice for the treatment of amoebae :a- Chloramphenicolb- Tetracyclinec- Gentamycind- Metronidazole30To prevent more absorption of the toxic drug we use :a- Waterb- Salt Sol.c- Salined- Charcoal31Hepatitis Vaccine dose is :a- Once / yearb- Twice / Yearc- Three times / Year32Which one is OTC drug :a- Simple analgesicb- Warfarinc- Ciprofloxacin33Anti-coagulant effect of Warfarin is decreased by :a- Rifampcinb- Aspirinc- Vit. K6d- Verapamil634One of the following is given once dailya- Amorphous Insulinb- Protamine Zinc Insulinc- Neutral insulind- Regular Insulin35The steady state conc. Of the drug in the plasma depends on :a- Direct proportion to the rate of administrationb- Indirect proportion to the rate of administrationc- Indirect proportion to the rate of eliminationd- Direct proportion to the rate of elimination36All these are Anti-Coagulants except :a- Warfarinb- Ancordc- Heparind- Dipyridamol37All these are Anti-Platelets except :a- Dipyridamolb- Aspirinc- Streptokinased- Presantine- Ticlopidine38Ferrograde is :a- Ferrous Sulphateb- Ferrous Citratec- Ferrous gluconate7d- Ferrous Fumarate739Procainamide is :a- Ca channel blockerb- Nifedipinec- Lisinoprild- Qunidine40What is the mechanism of action of Vit. K ?41Thiazide diuretics cause all the following except :a- Hypokalamiab- Hypercalcemiac- Hyperuricamiad- Hyponatrimiae- Hyperglycemiaf- Hypernatremia42Treatment with anti-arrhythmic drug depends on except :a- Type of medicationb- Period of medicationc- Patient sex43Elimination of Digoxin is mainly by :a- Kidneyb- Liverc- Bothd- None of the above44Dobutamine is given I.V. because :a- It is not stable in the gastric PHb- It is needed in large quantities in case of oral route8c- It is eliminated very quickly845Amilorid as trimetren causes :a- CNS disturbancesb- Hyperkalamiac- Hypokalamiad- Not affect K [ Potassium ]46What is the most drug can cause damage if it is given OTC ?a- Captoprilb- Warfarinc- Chlorothiazided- Rifampcin47Drug physical dependence is as same as drug abusea- Trueb- false48Mention two Thiazide diuretics ?49What is the difference between QID & Q6H ?QID =Q6H =50What is the difference between the following anti-fungal ?Miconazole =Amphotercin =9Griseofulvin =951Give the indication of the following drugs :1- Gimfibrazole2- Cisapride3- Fluoxetin4- Carbimazole5- Imipramine6- Ipratropium Br.52All are anti-metabolic except :a- Methotrexateb- Flurouracilc- Cytabrind- Azothiopine- Cyclophosphamide53Cefaclor is :a- Ist, Generation Cephalosporinb- 2nd, generation Cephalosporinc- 3rd, generation Cephalosporind- None of the above54Which Aminoglycoside antibiotic can be taken orally ?a- Gentamycinb- Neomycinc- Amikacind- Tobramycin55Teicoplanin antibiotic has similar effect on Gram positive as :a- Vancomycinb- Jamicacinc- Gentamycin10d- Kanamycin1056Which one is not Tetracycline ?a- Minocyclineb- Demeclocyclinec- Doxycyclined- Clindamycin57Which one is not Ca channel blocker ?a- Verapamilb- Deltiazemc- Amlodipined- Cinnarzine58Mesalazine is used for59Mention 4 lipid soluble vitamins ?60Imipenam [ Carbapenam ] is61All These medications are used in treating T.B. except :a- Cyclosporinb- INHc- Cycloserind- Rifampcin62All These drugs are anti-cholinergic except :a- Iprotropiumb- Atropine Sulphatec- Benzatropine Methylate11d- Dobutamin1163All Of These are antibiotics except :a- Zalcitabinb- Cefaprozilc- loefloxacind- Cefopodoxin64There is one drug is used for HIV :a- Zalcitabinb- Kinasterdinc- Cefaprozild- Enoxacin65Which one is Suprax ?a- Cefiximeb- Itraconazole66Which one is Sporanox ?a- Cefiximeb- Itraconazole67All of These can be used in treating leprosy except :a- Dapsonb- Rifampcinc- Clofazimined- INH68One of these is not like the others :a-Timololb- Acebutalolc- Labetolol12d- Betaxolol1269Which is not Aminoglycoside ?a- Netilimicinb- Tobramycinc- Kanamycind- Lymecyclin70Betahistine HCLa- For Mieniere diseaseb- Antihistaminec- Analgesicd- a & b71Which one is not 5HT3 antagonist ?a- Tropisetronb- Ondansetronc- Domperidone [ Motilium ]d- Granisetron72Which is not oral anti-coagulant ?a- Warfarinb- Enoxaprinec- Phenidioned- Nicoumolone73Which is correct ? Diazepama- Can cause muscle spasmb- Is taken I.M. onlyc- Is derivative from Morphined- Is not used for long term1374Maximum dose of Paracetamol is Gm / day1375The duration of treatment of T.B. by CTC is :[ CTC is Tuberculosis Committee Thoracic Society ]a- One weekb- Two monthsc- One monthd- 6 months76Metoclopramide is77Which one is contra-indicated in pregnancy :a- Sucralfateb- Ethambutolc- Chlorphenramined- Ciprofloxacin78What is the definition of Bioavailability of the drug ?79Give an ex. Of a drug induce Hepatotoxicity ?1-2-3-4-80Give an ex. Of a drug induce Nephrotoxicity ?141481Give the anti-dote for each of the following :HeparinParacetamolWarfarinMorphine82What is the generic name of Vit. B 12 ?83Zidovudine is used for84What is the meaning of poor patient compliance ?85Fluxotine is :86Omeprazole is87Mention two diseases cause Edema ?1-2-88Give examples of drug - drug interactions ?1-2-3-4-5-6-157-1589Generic name of :Vit. B1Vit. B2Vit. B6Vit. B1290All of these are the components of Calamine lotion B.P. except :a- ZnOb- calaminec- Sod. Citrated- Bentonitee- Sod. Sulphate91Terbinafine is used topically for :a- Eczemab- Candidac- Fungal infections92Which one is not contra-indicated in pregnancy ?a- Captoprilb- Enalprilc- Lisinoprild- Methyldopa93PCP [ Pneumocystis Corini Pneumonia ]a- Virusb- Bacteriac- Parasited- Mycobacterum94Which of the following is not antibiotic ?a- Erythromycinb- Cefprozilc- Ceprodoxin16d- Finasteride1695Which one is used for Benign Prostatic Hyperplasia [ BPHP ]a- Flumazenilb- Cefprozilc- Mivacurimd- Finasteride96All of these are third generation Cephalosporin except :a- Cefiximeb- Cefopodoximec- Ceftriaxoned- Cefotaxime97Which of the following is not mucolytic ?a- Bromohexinb- Carbocistenec- Ambroxold- guaphenesine- Dextromethorphan98Which one is anti-platelet ?a- Ticlopidineb- Desfluronc- Aldesleukind- Atovaquon99All of these anti-neoplastic except :a- Aldesleukinb- Teniposidec- Pentostatin17d- Amlodipine17100Which is not Benzodiazepine ?a- Temazepamb- Nitrozepamc- Loprazolamd- Clozapine101Potassium supplement must not be given with Triametren1- False2- True102Misoprostol inhibit gastric acid by blocking the hydrogen potassiumadenosine triphosphate enzyme system of gastric cell[ Misoprostol is Cytotic ]1- False2- True103MMR vaccine is104Oral re-hydrate solution is one of the following :a- Sod. Citrate - Pot. Chloride - Glucoseb- Sod. Citrate - Pot. Chloride - Sod. Chloridec- Sod. Chloride - Pot. Citrate - Sod. Citrate - glucosed- Sod. Chloride - Pot. Chloride - NaHCO3 - Citric acid105Gemfibrazilea- Increase HDL & Triglyceridesb- Increase HDL & decrease Triglyceridesc- Decrease HDL & LDLd- Increase LDL & Triglycerides.106Nitroprusside Sod. Is :a- Potent vasodilatorb- potent diureticc- potent vasoconstrictor18d- Anti-arrhythmic agent.181074 drugs need monitor for their serum level1-3-2-4-108For Fluxacillin, all these statments are wrong except :a- It is activated by Penicillinase enzymeb- It is taken by oral route onlyc- It is base stabled- It is better absorbed than Cloxacilin109What are the instruction for patient taken MetamucilOr any other bulk foaming laxative as Bran, methyl Cellulose &Psyllum :110CytotecIs used for111Mention two drugs from HMG - COA- reductase inhibitors112HMG-COA-Reductase Inhibitor is113Source of Human Insulin is E-Coli by :1919114Zinnat contains :115Thiabendazole is one of Thiazides diuretics1- False2- True116Praziquantil is :a- Cause loss of intracellular calcium of wormsb- Used for malariac- Biltracid is the trade named- a & c117Nitrofurantoin is indicated for :a- Viral infectionb- GIT Infectionc- Urinary tract infection [ UTI ]d- URI118Vit. Ka- Increase formation of clotting factorb- Increase conversion of Vit. K to the active formc- Prevent conversion of Vit. K back to the active formd- Non of the above119Quinidine Sulphate is :a- Anti-arrhythmic agentb- Anti-malarial agentc- Anti-hypertensive agent20d- a & c20120ACE stands for :a- Converting Ag11 to vasoconstrictor Ag1b- Converting Ag1 to vasoconstrictor Ag11c- Converting Ag1 to vasodilator Ag11d- Converting Ag11 to vasodilator Ag1121One of these side effects not occur with Thiazide diureticsa- Hypernatraemiab- Hypoglycemiac- Hypokalamiad- Hyperuricamia122Ipeca is emetic agent which induce emesis through :a- Stimulation of the stomachb- Stimulation of the CTZc- a & bd- Inhibition of the stomach through CNS123Theophyllin isa- Bronchdilatorb- B2 agonistc- Cause Bradycardiad- All of the above124Schedule of immunization for HBV is :a- Single doseb- Two dosesc- Three dosesd- Five doses125Itraconazol21Is21126Treatment of anaphylactic reaction is initiated by immediate :a- Hydrocortisoneb- Cimetidinec- Human albumind- Epinephrine127Introduction of emesis is not indicated in the following except :a- Caustic substance ingestionb- CNSc- Seizuresd- Paracetamol poisoning128all of these are anions except :a- Phosphateb-Acetatec- Sodiumd- Chloride129Astemizole is130Triazole isa- Antifungalb- Trade name of clotrimazolec- Trade name of amphotercin Bd- Nystatin131With Minoxidil, all these parameters should be monitored except :a- Urine flow rateb- B.P.c- Pulse rate22d- Body weight22132Aspirin is recommended with one of the following :a- Anti-coagulantb- Chicken boxc- Influenza symptomsd- Dys-menorrhoea133Which is not true with Tetracyclinea- Broad spectrum bacteriostaticb- Broad spectrum bactericidalc- Inhibit protein synthesisd- Used for acne134Give 2 indications for allopurinol1-2-135Give an ex. Of non sedating anti-histamines136Famotidine is137What are the effects of Captopril1- Decrease conversion of Ag1 to Ag112- Effective hypotensive when others are contra-indicated[ B blockers & diuretics ]138Type 2 Diabetics is characterized by :a- Lack of response to Insulinb- Lack of response to sulphonylureac- Respond to dietary therapy alone23d- Slowly increasing sulphonylurea requirement23139Give 2 side effects of Aminoglycosides ?140Mention 2 quinolones12141Give 3 drugs as Pot. Sparing diuretics142Acetazolamide is143Which one reduces the metabolism of other drugs in the liver :a- RifampcinB- Vit. Cc- Cimetidined- Metronidazole144All of these can be dispensed without prescription except :a- Aspirinb- Maaloxc- Bisacodyld- Tegretol145Simvastatin is used for146Acetohexamide is147List the trade name of the following :PindololBaclofen24Omeprazol24148What is the meaning of each of the following :POMBIDECGG.6.PDBPC149Which of these is Pro-druga- Ampicillinb- Erythromycinc- Pivampicillind-All of the above150500 ml Normal saline 0.9 % contains gm. NACL151Mention 3 ACEI152Levodopa with Cardiodopa for the treatment of153Specific Serotonin reuptake inhibitor are used as :a- Antihistaminicb- Antidepressantc- Antihypertensived- antiemetic154Which of these has no vasodilator effect :a- Methyl dopab- Hydralazinec- Enalpril25d- Prazocin25155Enalpril is the prodrug of :156Mention 3 drugs contraindicated in pregnancy :123157List 3 drugs used to treat T.B. :123158Calcipotriol is indicated for :a- Psoriasisb- Hypertensionc- Calcium supplementd- Acne159List 8 side effects of Corticosteroids :1234567826160Maximum dose of Captopril is mg / day26161Amantadine is used for all of the following except :a- Antiviralb- For influenza Ac- Anti-parkinsonismd- For influenza B162All are viral infections except :a- Hepatitis Bb- Influenzac- Herpes Zosterd- Rikettsia163At the cardiac arrest [ shock ] . The drug of choice is :a- Epinephrineb- Propranololc- Hydrocortisoned- Saline sol.164Give ae example of cardio selective B blocker ?a- Atenololb- Bisoprololc- Esmolold- Betaxolole- Metoprololf- Acebutolol165Drugs to pass B.B.B. should be :a- Unionized hydrophilicb- Ionized hydrophilicc- Unionized lipophilic27d- Ionized lipophilic27166All of these are anti-parkinsonism except :a- Amantadinee- Lysurideb- Apomorphinef- Pergolidec- Bromocriptineg- Levodopad- Primidoneh- Selegiline167All of these are anti-metabolite [ cytotoxic ] except :a- Methotrexated- Azothioprinb- Cylarabine- Mercaptopurinec- Cyclophosphamidef- Flurouracil168All of these are antichlonergic except :a- Atropine sulphated- Iprotropium bromideb- Hydroatropinee- Butrepium bromidec- Mebeverine169All of these are corticosteroids except :a- Ondansetrond- Beclomethasoneb- Prednisolonee- Dexamethazonec- Triamcinolonef- Methyl prednisolone170When newly married do not want child. How to arrangea- Arrange contraception.b- Send wife to the family doctorc- Send the wife to her mother171Side effects of Insulin ?1Local reaction [ urticaria ]2Hypoglycemia283Fat dystrophy at site of injection28172One of the following is the main side effect of insulin :a- Hypoglycemiab- Fluid retentionc- Hyperglycemiad- All of the above173The only aminoglycoside can be taken orally is :174Chloramphenicol affect liver inhibitory enzyme. Soa- Decrease metabolism & increase responseb- Decrease metabolism & decrease responsec- Increase metabolism & increase responsed- Increase metabolism & decrease response175OTC simple analgesic is176Enteric coated taba- Pass the stomach & release in the intestineb- Pass the stomach & intestinec- Release in the stomach177All of these are true for Levodopa except :a- precursor of dopab- Does not pass B.B.B.c- Effective in parkinsonismd- Stimulate dopamine178Morphine & Morpin are similar in29179Cytocin is29180The conc. Of the drug on Exp. Date is :a- Not less than 100%b- Not less than 90%c- From 90-110%d- Non of the above181If you have prescription contains Inderal and the patient iswheezing. What is your advice ?182Bioavailability means :a- Rateb- Extentc- Rate & extentd- Non of the above183Pharmacokinetics means :a- Effect of the body on the drugb- Drug - receptor reactionc- Non of the above184Surfactant not used orallya- Tweenb- Sponc- Na lauryl sulphate30d- B & C30185Type 1 Diabetes. advise to use :a- InsulinB- Glibneclamidec- a & bc- Non of the above.186Type 11 Diabetes. advise to use :a- Diet controlb- Insulinc- Sulphonyl uread- All of the above187One of the following is the main side effect of insulin :a- Hyperglycemiab- Hypoglycemiac- Fluid retentionC- All of the above188Pentobarbital differs from Phenobarbital in :a- Longerb- FasterC- Not use very muchd- a & b189Morphine & morpin are similar in :a- Miosisb- AddictionC- Analgesic31d- All of the above31190Theophyllin dose in children.a- Increased metabolism & dose must be increased .b- Decreased metabolism & dose must be increased .c- Decreased metabolism & dose must be decreased .191Biotransformationa- More lipid solubleb- Less lipid soluble.192Phenylephrine is used for :a- Decongestantb- For runny nosec- Sympathomimetics.d- All of the above.193Oxytocin produces all the following except :a- Progestron releaseb- Uterine stimulationc- Labor inductiond- Mammalian glands stimulation194Binding to the plasma protein , means :a- Increase half life32b- Decrease half life.32195New & best therapy for peptic ulcer is :a- Antacid + H2 antagonist.b- Use more than one H2 antagonist.c- Four medicines including antibiotic.196In case of Osteoarthritis & peptic ulcer of elderly patients use :a- Paracetamolb- Strong NSAIc- Aspirin197Give names of drugs that change the color of urine ?1Nitrofurantoin2Phenazopyridin3Rifampcin198The drug of choice for Febril Convulsion in children is :199Cyproteron [ Androcur ] is used for :200Immunocompetent means ?3333201Immunocompromised means ?202Which of the following is not cardio-specific B blocker ?a- Atenololb- Acebutololc- Satolold- Labetolol203Controled released drug delivery depends on :a- Body fluid interactionb- Enzymatic reactionsc- Ready programmed & no influece of the body fluidd- Stomach PH.204The conc. Of the drug on exp. Date is :a- Not less than 100%b- Not less than 90%c- From 90 - 110%d- Not of the above205Type 11 Diabetes. Advise to use :a- Diet control.b- Insulinc- Sulphonyl Urea.34d- All of the above.34206All of these are antichlonergics except :a- Atropine Sulphateb- Hydro-atropine.c- Mebeverine.d- Iprotropium Bromide.e- Butrepium Bromide.207Pharmacokinetics means :a-Effect of the body on the drug.b- Drug - Receptor reactionc- Non of the above.208Specific Serotonin reuptake inhibitors are used as :a- Anti-histaminicb- Anti-depressantc- Anti-hypertensived- Anti-emetic209Type 1 Diabetes. Advise to use :a- Insulinb- Glibneclamidec- a & bd- Non of the above.210Biotransformationa- More lipid soluble35b- Less lipid soluble35211Pentobarbital differs from Phenobarbital in :a- Longerb- Fasterc- Not use very muchd- a & b212Which one of these can not be used in pain crisis :a- Morphineb- Naproxinec- Codeined- Colchicin [ used mainly in gout pain ]213All of the following are Ca ++ channel blockers except :a- Mesalamineb- Verapamilc- Cinnarzined- Amlodipine214One of the following is not used for Parkinson disease :a- Pergolideb- Seleglinec- Amantadined- Disulfiram215All the following are ACE inhibitors except :a- Captoprilb- Ramiprilc- Lisinopril36d- Isradipine36216Quinidine Sulphate Is :a- Anti-arrhythmicb- Anti-malarialc- Anti-hypertensived- a & b217All the following are used as Anti-tussive except :a- Guaifenesinb- Dextromethorphanec- Codeine Phosphated- Morphine Hydrochloride218Nitrous Oxide is used in anaesthesia because :a- It is non explosive & non inflammableb- It induces rapid induction & rapid recoveryc- It is potent muscle relaxantd- All of the above219All of the following have GIT upset except :a- Phenytoinb- Phenobarbitonc- Ethosux - Pn 7 ded- Benzodiazepam220A patient has a prescription of Erythromycin 500 mg tablets every 6 hours.and you do not have this anti-biotic. You can phone the doctor to changeit with :a- Clarithromycinb- Amoxicillinc- Clindamycin37d- Ampicillin37221A child of 41 degrees centigrade, when his father ask you about him,you must tell him to :a- Go to hospital which is 30 m. distance.b- Sponge by tap water and go to hospital.c- Take 1 GM. Paracetamold- Go to home.222The patient under the prescribing drug.when he comes to you , Then you must tell him :a- All the drug side effects.b- Some relatively side effects.c- Another side effects.d- Non of the above223A patient has a prescription of Enalpril + KCL,what are you ask him ?a- Any product of K do you need.b- You take any other anti-hypertensivec- You need syrup or tablets.d- Not of all224ACE inhibitors are used for the treatment of :a- Asthmab- Migrainec- Hypertensiond- All of the above225New non sedative anti-histaminics act through :a- H1 antagonistb- H2 antagonistc- Muscarinic receptors38d- B1 antagonist38226All of the following are B antagonists except :a- Salbutamolb- Metoprololc- Nadolold- Atenolol227B agonist causes :a-Increasing of Oxygen consumptionb- Increasing of ectotopic effectc- Increasing of inotopic effectd- All of the above227Atropine is used as pre-anaesthetic to :a- Give skeletal muscle relaxationb- Decrease salivac- Treat the side effects of anesthesic.d- Help the sleeping effect of anaesthetic228A patient weighing 10 kilograms is given a paracetamolone teaspoon full every 4-6 hours.you should call doctor and tell him that :a- The dose is very highb- The dose must not exceed 180 mg dailyc- The dose is not sufficientd- There is no need to call the doctor.229Malignant hypothermia is usually a side effect of :a- Anaesthesiab- Azathropinc- Phenytoin39d- Aspirin39230The common side effect of Sulphonylurea is :a- GIT upsetb- Thyrotoxosisc- Hypoglysurisd- All of the above231Vasopressine is used for the treatment of :a- Diabetes insipidusb- Diabetes mellitus type 1c- Diabetes mellitus type 2d- Anti-hypertensive232Pseudomembraneous colitis is a side effect of :a- Vancomycinb- Clindamycinc- Reserpined- INH233Phenobarbiton induces liver microsomal enzymeswhen taken with Warfarin anti-coagulant leads to :a- Increasing the activity of liver enzymesso, decreasing the activity of Warfarinb- Increasing the activity of liver enzymesso, increasing the activity of Warfarinc- Decreasing the activity of liver enzymesso, decreasing the activity of Warfarinc- Decreasing the activity of liver enzymes40so, increasing the activity of Warfarin40234Tetracycline, when taken with metals such as Calcium, Iron & Aluminiumfrom a chelate which is :a- Inactive & not absorbedb- Active & poorly absorbedc- Inactive & poorly absorbedd- Active & absorbed235Disulfiram is used for :a- Treatment of chronic alcohol dependenceb- Protection of liver cells from alcoholismc- Prevention of conversion of acetaldehyde to acetic acidd- All of the above236The drug transfer through the cell membrane by :a- Aqueous diffusionb- Osmotic pressurec- Lipid dissolved- Non of the above237Protein bound drugs forming a compound which is :a- Inactive while the free part is activeb- Highly active while the free part is inactivec- Less active while the free part is actived- Active while the free part is more active238The drug metabolism in the body occurs in :a- GIT & Plasmab- Gut wall during absorptionc- Gut wall during absorption & in plasma stream41d- Liver , Kidney & bowel mucosa41239Clonidine is used as :a- A drug that prevents the recurrence of Migraineb- Anti-hypertensive acting centrallyc- a & bd- Non of the above240Dolomol is :a- Paracetamol with analgesic & anti-inflammatoryb- Paracetamol with analgesic & without anti-inflammatoryc- Non Paracetamol with analgesic & anti-inflammatoryd- Non Paracetamol with analgesic & without anti-inflammatory241Metoclopramide gives its anti-emetic through :a- Peripheral actionb- Dopaminergic receptorsc- Muscarinic receptorsd- All of the above242Dobutamine is used as :a- Parasympathomimeticb- In cardiac surgeryc- Hypotensive agentd- All of the above243The following are the indications of Diazepam except :a- Anti-Psychoticb- Epelipsyc- Analgesic42d- Hypnotic42244The diuretic which is used with Captopril is :a- Aldactoneb- Ethacrynic acidc- Furosemided- Non of the above245The following drugs are used for the treatment of anxiety except :a- Propranololb- Diazepamc- Homatropined- Mebrobamate246All the following are macrolides except :a- Clarithomycinb- Roxithromycinc- Erythromycind- Clindamycin247The main use of Metronidazole is :a- Anti-amoebiasisb- Anthelminticc- Anti-bioticd- Anti-malarialALL THE BEST & SUCCESS4343

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SujectsDEFINITIONSDRUGIs any small molecule that when introduced into the bodyaffect the functions.PHARMACODYNAMIC :Is the interaction between the drug & the body.OR :The effect [ desired & undesired ] of the drug on the bodyPHARMACOKINETIC :Is the way of the body to handle the drug.[ through absorption, distribution, metabolism & excretion ]EFFICACY :Is the relation between occupancy of receptor sites & thepharmacological response.OR :Is the degree of response regardless the dose.POTENCY :Is the dose or concentration of the drug required to producea given response.OR :Is the minimal dose required for the needed response.THERAPEUTIC INDEX :Is the ratio between TD50 : ED50.TD50 is toxic dose that produce undesired effect.ED50 is effective dose that produce desired effect.IDIOSYNCRASY :Is unusual drug response.i.e. single individual may respond differently to the same drugat different times during the course of treatment.HYPERSENSITIVITY :Is allergic or any other immunological response to the drugTOLERANCE :Is the decreasing of the intensity of response during thetreatment. [ the patient feels to increase the dose of thedrug to get the same response ]TACHYPHYLAXIS :When responsiveness decreases rapidly after drug administrationBIOAVAILABILITY :Measure of speed & completeness of absorption fromthe site of administration.CLEARANCE :Is the measure of the ability of the body to eliminate thedrug through the urine[ relative to the plasma drug conc. ]VOLUME OF DISTRIBUTION :Is the measure of the space in the body available to containthe drug.HALF LIFE :Is the time required to attain 50% of steady stateOR :Is the time to decay 50% of the steady state.MAINTENANCE DOSE :The dose needed to maintain a chosen steady state.LOADING DOSE :Is the amount of the drug needed to achieve a given steadystate conc. In the plasma.XENOBIOTICS :Substances absorbed across the lungs, skin or ingested withfood or drinks or drugs for recreational purposes.ORPHAN DRUGS ;Drugs for rare diseases.1-What is the mechanism of drug permeation ?There are 4 mechanisms :1- Aquous diffusionthrough gut or cornes.2- Lipid diffusionthrough cell membranes.3- Special carriersas B.B.B.4- Pinocytosisdrugs of exceptional large size2-What are the factors that affect the drug distribution ?1- Protein binding2- Blood flow3- Membrane permeability4- Tissue solubilitypageDiabetes Mellitus [ DM ]IDDMNIDDMInsulin Dependant DMNon Insulin Dependant DMType 1Type 11Type 1 :Type 11 :Is a severe form. Mainly in juveniles &Mainly in adults ( obese )rare in adults ( non obese & elderly )insulin is insufficient orOccurs due to infections as mumpsthe tissue sensitivity toor exposure to destructive substanceinsulin is low or B cells impairedas Cytotoxics. There is ketosis.to respond to Glucose.* Insulin Structure :It is 51 amino acids in two chains [ A & B ] linked by disulphide bridges.Beef insulin is differ in 3 amino acids. But Pork is differ in one only.Human Pancreas has Islets of Langerhams which has 4 types of cellsA cells [ alpha ]B cells [ beta ]D cells [ delta ]F cells [ PP ]secretessecretessecretessecretesglycogenInsulinsomatostatinpancreatic polypeptides* Insulin preparations ;1- Short acting Insulin :a- Regular type [ crystalline zinc ]clear sol. & the only one can be taken I.V.b- Semilente [ amorphous crystalline ]2- Intermediate acing Insulin :a- Lente type is mixture of [ 30% semilent & 70% ultralent ]b- NPH [ protamine zinc - Isophane ]ex. most common use one is 30/70 type ( NOVOLIN ) from Squibbit is 70% NPH & 30% regular type.3- Long acting Insulin :ex. Ultralente* Complications of Insulin Therapy ;1- hypoglycemia [ treated by sugar intake ]2- lipodystrophy at the site of injection.3- Two immunopathology disordersa- Insulin allergylocal & systemic urticariab- immuno insulin resistancethe tissues sensitivity to insulin decreased due to IgGanti-insulin antibody neutralize the action of insulin.** Oral Hypoglycemics :1- Sulphonyl Ureasmainly are used for type 11 DMas Tolbutamide - Glibenclamide [ Daonil ] - Tolazamide -Acetohexamide - Glipizide - ChlorpropamideMechanism of actiona- Stimulate B cells to release Insulinb- Decrease the serum glycogenc- Potentiate the action of Insulin on the target tissues.2- Biguanides :It decreases the level of glucose in the bloodas Phenformin [ Glucophage ] - Metformin - BuforminpageBronchodilators & AsthmaDrugs used to treat asthma are :1- Cromolyn Sod.ex. Sod. Cromoglycate for prophylaxis.2- Methyl Xanthinesex. Theophylline - Theobromine - CaffeineAminophylline [ theophylline + ethyldiamine ]Pentoxyfylline [ Trental ]3- Sympathomimetics :ex. Ephedrine - Epinephrine - Isoproternol [ non specific B agonist ]B2 selective agonists as :a- Terbutaline [ Bricanyl ]b- Metaproternol [ Alupent ]c- Albuterol [ Salbovent , Ventolin ]4- Anti-muscarinic drugs :ex. Atropine - Ipratropium [ Atrovent5- Corticosteroids :ex. Beclomethasone - Dexamethazone - Triamcinolone.pageAUTONOMIC NERVOUS SYSTEM [ ANS ]Q- What is the difference between ANS & endocrine system ?** Is in the mode of transmissionin case endocrine system via blood - borne hormones.in case ANS via chemical transmission as acetylcholine & nor-epinephrineAnd both of them is used to control & integrate the body functions.Q- The nervous system is two divisions :a- Autonomicb- SomaticWhat is the difference ?** The autonomic to control the activities that are not under consciousas blood flow , cardiac outputThe somatic to control the activities that under conscious.as respiration , exercise.Q- The autonomic nervous system is sub-divided into :a- Sympatheticb- ParasympatheticWhat is effect on the body activities of both of them ?OrganSub-organSympatheticParasympatheticactionreceptoractionreceptor1- HeartVascular musclesconstrictalpharelaxMuscarinic/McontractilitycontractalpharelaxM2- Lungsbronchial musclesRelaxB2contractM3- G.I.T.wallsRelaxB2contractMsphincterscontractAlphaRelaxMSecretions**********IncreaseM4- Sex OrgansPenisejaculationalphaerectionMuterusRelaxB25- Urinary t.Bladder wallRelaxB2contractMsphincterscontractalphaRelaxM6- Skinsweat glandsIncreaseMHeat stressIncreasealpha7- EyeRadial musclescontractalphaRelaxMcircular musclescontractalphaRelaxM[ mydriasis ][ miosis ]A- PARASYMPATHOMIMETICS :A- Direct actingB- Indirect actingCholinesteraseinhibitorsmuscarinicnicotinicreversibleirreversible1- CarbamatesPhosphates2- Edrophoniumestersalkaloids3- Neostigmine1- Acetylcholineas Muscarine & Nicotine4- Phtsostigmine{ eserine }2- Bethanchole3- Methacholine4- Carbachol** The main uses of Parasympathomimetics :1- GlaucomaThere are two types of glaucoma1- Primary2- SecondaryIt is caused by surgical procedures( chronic )Angle closureOpen angle( Acute )( chronic )* for the closure angle type :is kind of emergency & needs medication then surgery.as Pilocarpine , physostigmine , Carbachole & Methacholine.* for the open angle type :only use medication2- Postoperative ileus & Congenital megacolonUse Bethanichole & Neostigmine3- Myasthenia Gravis :Use Edrophonium & Neostigmine*** Antidote :1- Atropine2- PralidoximeB- PARASYMPATHOLYTICS :They are contraindicated in Glaucoma & in elderly patients with urinaryretention.Examples :1- Anti-muscarinics : Atropine - Homatropine - isopropamideCyclopentolate - HyoscyamineScopolamine - Propanthine2- Ganglion Blockers : Mecamylamines - Hexamethonium - Trimethaphan3- Cholinesterase regenerator : Pralidoxime4- Sympathomimetics : Nor-epinephrine** It is used to treat Mashroom poisoningalso Atropine is used before anesthesia to reduce secretions & retinaexamination & as anti-spasmodic.C- SYMPATHOMIMETICS :mainly this group has positive effect on the heart & C.V.S.This group is classified according the selectivity on Alpha & Beta receptors.Alpha AgonistsB1 & B2 non-selectiveB2 selectiveB1 selective1- Epinephrine1- Epinephrine1- Albuterol ( ventolin )1- Norepinph..2- Nor-epinephrine2- Isoproternol2- Terbutaline ( Bricanyl2- Dobutamine3- Phenylephrine3- Metaproternol ( Alupent )4- Methoxamine4- Ritodrine** Main Uses :1- Hypotension2- Heart block3- Bronchodilators4- Retinal examinationD- SYMPATHOLYTICS :mainly are used for treating hypertension.Alpha blockersBeta blockersB1 blockersB2 blockers1- Prazocin ( Minipress )1- Propranolol ( Inderal )1- Metoprolol ( Lepressor )Butoxamine2- Phenoxybenzamine2- Timolol2- Acebutolol ( Sectral )3- Phentolamine3- Nadolol ( Corgard )3- Atenolol ( Tenormin )4- Tolazoline ( Priscoline )4- Pindolol ( Visken )4- Esmolol5- yohimbine ( for sex disorders )5- AlprenolN.B.Levobunolol ( Betagan liquifilm )Betaxolol ( Betoptic )** Uses :1- Hypertension2- Pheichromocytoma3- Glaucoma4- Ischemic heart disease5- Cardiac arrhythmia7- Hyperthyroidism.ANTIMICROBIAL DRUGS** Mechanism Of ActionAntimicrobial actionAntimicrobial group1- Through inhibition of cell wallPenicillin's, Cephalosporins, BacitracinsynthesisCycloserin, Vancomycin2- Through inhibition of cellAmphotericin B, Nystatin, ImidazolesmembranePolymyxines3- Through inhibition of proteinChloramphenicol, Erythromycin's,synthesisTetracycline's, Aminoglycosides4- Through inhibition of nucleicQuinolones, Rifampin, Sulfonamides.acid synthesisQ- What is the definition of Cross Resistance ?When micro-organisms resistant to a certain drug may also be resistantto other drugs.CEPHALOSPORINSIst, generation Gr.2nd, generation Gr.3rd, generation Gr.1- Cephalexin ( Keflex )1- Cefaclor ( Ceclor )1- Cefoperazone ( Cefobid )2- Cephalothin ( Keflin )2- Cefuroxime ( Zinacef - Zinnat )2- Cefotaxime ( Claforan )3- Cephradin ( Velosef )3- Cefoxitin3- Cefotetan4- Cefazolin ( Kefzol )4- Cefonicid4- Ceftizoxime ( Cefizox )5- Cefadroxil ( Ultracif )CHLORAMPHENICOL** Side Effects :1- G.I.T. disturbances.2- Bone Marrow Disturbances [ aplastic anemia ]3- Newborn infants toxicity [ gray syndrome ]TETRACYCLINE'S** Side Effects :1- G.I.T. side effects2- It affects the bony structures & teeth.3- Liver & kidney toxicity.4- Photosensitization [ specially Demecycline ]* examples of tetracycline's :1Doxycycline ( Vibramycin )2Minocycline ( Minocin )3Oxytetracycline ( Terramycin )4TetracyclineAMINOGLYCOSIDES* Examples :1- Amikacin ( Amikin )2- Gentamycin ( Garamycin )3- Neomycin4- Sreptomycin5- Tobramycin ( Nebcin )

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