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黄 疸 jaundice. 定义. 血清中 总 胆红素 浓度 增高 达 34.2 mol/L 以上 (2.0 mg/dl ),皮肤、巩膜、黏膜、体液及其它组织黄染,临床出现黄疸 血清中 总 胆红素 浓度 增高 在 17.1-34.2 mol/L ( 1.0-2.0 mg/dl )之间,肉眼看不出黄疸,称隐性黄疸 黄疸是症状,也是体征. 血清胆红素正常值. 总胆红素 ( TB ) 1.7-17.1 mol/L (0.1-1.0mg/dl) 结合胆红素( CB ) 0-3.42 mol/L(0-0. 2mg/dl) 非结合胆红素( UCB ) - PowerPoint PPT Presentation
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jaundice
34.2 mol/L(2.0mg/dl17.1-34.2 mol/L1.0-2.0 mg/dl
( TB ) 1.7-17.1mol/L(0.1-1.0mg/dl)CB 0-3.42mol/L(0-0. 2mg/dl)UCB 1.7-13.68mol/L(0.1-0. 8mg/dl) ( CB/TB < 20% )
80-85%4275 mol/L15-20%171-513 mol/L/
+ + +
+ - -UCB
- Disse + YZ -Y/Z
+ CB
68-473 mol/L/ 80-90%
10-20% 6.8 mol/L/
(unconjugated bilirubinUCB) (van den Bergh)UCBCBCB1CB UCB=TB- CB
(conjugated bilirubinCB)
:
- - UCB > UCB
UCB
(CB)
:
:
UCB UCB UCB
UCB
(CB) CB + CB
TBUCBCBCB/TB >30-40%
:
:
UCB
(CB)
(CB) (CB)
+
TBCBCB/TB > 50-60%
TB CB - CB/TB 30-40% >50-60% - + ++
Gilbert
Crigler-Najjarnuclear jaundice)
Roter
Dubin-Johnson
(Charcot)
BXERCP
PTC:19899131-CTMRI):CT
Dubin-Johhson
JaundiceScleral icterun; serum total bilirubin; Unconjugated bilirubin; conjugated bilirubinSenescent red blood cell; hemoglobin; heme; bilirubin; urobilirogen; urobilinReticuloendothielial system; albumin; glucuronic; distal ileum/colonprotein ligandin Y/Z
JaundiceHemolytic jaundice; hepatocellular jaundice; cholestetic jaudice; inherted nonhemolytic jaundiceVan de Bergh reactionhyperbilirubinemia
TB 160.3 umol/L; CB 114.9 umol/L; AKP 344(42-140)U/L; -GT 268(8-58)U/L; LDH 261(114-240)U/LALT 42(0-75)U/L ; AST 234(0-40)U/LTP 62(60-80)G/L; Albumin 23.5(35-55) G/LCB/TB 0.7168Albumin 5.4 G/L; SAAG 18.1G/L
571+MRI:
Thank you