(org)
100 mL 200 200 mL 240
200 mL org
100 mL aq
2 A 200 + 67 = 267
100 mL org
100 mL aq
A 200
2
2302244 Anal Chem II
A 240
200 mL x 1
[A]i = A (aq phase) i
i =
[A]o = A (org phase) i
[A]o = A (org phase) i
2302244 Anal Chem II
K of I2 = 85 [I2] 50.0 mL 1.00 x 10-3 M I2 a) 50.0 mL, b) 2 x 25.0
mL, c) 5 x 10.0 mL
()
= Phase ratio; Vorg/Vaq
2302244 Anal Chem II
like dissolves like
KD
benzoic acid naphthalene dichloromethane (CH2Cl2) 5% NaOH NaHCO3
benzoic acid (CH2Cl2)
5% NaOH
dichloromethane (CH2Cl2)
pKa = 4.2
pKa ~ 10
dichloromethane (CH2Cl2)
p-chloroaniline benzoic acid ( pH < pKa 2 ~ 2) benzoic acid
CH2Cl2
5% HCl
pKa = 4.6
pH > pKa 1.5
Separation Techniques 1
[HQ]org [M2+]aq
Separation Techniques 1
(absorption)
liquid-liquid extraction
Separation Techniques 1
sorbent
Male Luer tip fitting
2302244 Anal Chem II
sorbent compressed air N2
(centrifugation)
SPE Tube
SPE Disk