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1 John. M. Sabol, Ph.D. AAPM 2012

1 John. M. Sabol, Ph.D. AAPM 2012amos3.aapm.org/abstracts/pdf/68-19951-234349-85796.pdf · 15 John. M. Sabol, Ph.D. AAPM 2012 Standard PA chest radiograph (l eft) and single slice

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  • 1John. M. Sabol, Ph.D.

    AAPM 2012

  • 2John. M. Sabol, Ph.D.

    AAPM 2012

  • 3John. M. Sabol, Ph.D.

    AAPM 2012

  • 4John. M. Sabol, Ph.D.

    AAPM 2012

  • 5John. M. Sabol, Ph.D.

    AAPM 2012

  • 6John. M. Sabol, Ph.D.

    AAPM 2012

  • 7John. M. Sabol, Ph.D.

    AAPM 2012

  • 8John. M. Sabol, Ph.D.

    AAPM 2012

  • 9John. M. Sabol, Ph.D.

    AAPM 2012

  • 10John. M. Sabol, Ph.D.

    AAPM 2012

  • 11John. M. Sabol, Ph.D.

    AAPM 2012

  • 12John. M. Sabol, Ph.D.

    AAPM 2012

  • 13John. M. Sabol, Ph.D.

    AAPM 2012

  • 14John. M. Sabol, Ph.D.

    AAPM 2012

    Cine loop of tomosynthesis slice images through the chest.

  • 15John. M. Sabol, Ph.D.

    AAPM 2012

    Standard PA chest radiograph (left) and single slice from the tomosynthesis imagedataset (right) of a patient presenting with a lesion in the lower left lung. Althoughthe lesion can be seen in the conventional image, it can be better visualized andcharacterized in the tomosynthesis slice. In particular it can be seen to be cavitated,characteristic of a tuberculosis infection.

  • 16John. M. Sabol, Ph.D.

    AAPM 2012

    Tuberculosis with Small cavityConventional PA x-ray (Left) and tomosynthesis slice image (right) of a tuberculosispatient with a small cavitated nodule.

    Image courtesy of Dr. M.J. Chung, Samsung Medical Center, Seoul Korea.

  • 17John. M. Sabol, Ph.D.

    AAPM 2012

    Accidental swallowing of a pill in a press-through package. Chest conventionalradiograph (left) and tomosynthesis image (right). The tomosynthesis image enablesimproved visualization of the object as a donut-like lucent area in the esophagus,whereas the foreign object is not visible on the conventional radiograph.

  • 18John. M. Sabol, Ph.D.

    AAPM 2012

  • 19John. M. Sabol, Ph.D.

    AAPM 2012

    Tomosynthesis image reveals a subtle fracture of the acetabulum, not seen onconventional hip radiograph.

  • 20John. M. Sabol, Ph.D.

    AAPM 2012

    Patient imaged for routine follow-up of treatment for a fracture of the scaphoid.Conventional radiograph (left) appears to shown good evidence of healing(increased bone density at fracture site). However, examination of tomosynthesisimages shows that despite increased bone density, the fracture still remainsindicated by the gap in the bone (arrow in right image). This is a clear example ofhow overlying structures (in this case increased bone growth) can obscureunderlying pathology.

  • 21John. M. Sabol, Ph.D.

    AAPM 2012

    Following a snowmobile accident, a patient was imaged at a rural trauma clinic. TheAP radiograph on the left clearly shows a black line or shadow across the odontoidprocess raising the possibility of a fracture. A single slice from the tomosynthesisdataset (right image) removed the overlying shadow and the odontoid process wasreadily cleared for fracture. Had the ER physician not been able to clear the spine hewould have had to send this patient, via ambulance, to the nearest trauma hospital,over 4 hours away.

  • 22John. M. Sabol, Ph.D.

    AAPM 2012

    13 year old with dislocation Of epiphyseal (growth) plate of the femur in extreme hippain following surgery.

    Left: A post surgical projection image to determine if the implanted screw hadinvaded the joint space.

    Center and Right: Tomosynthesis imaging allows for complete assessment of thejoint without overlying structures with minimal metal artefacts. The tomosynthesisimages revealed that the screw had not invaded the joint space.

  • 23John. M. Sabol, Ph.D.

    AAPM 2012

    Left: Tomosynthesis images of a trauma patient imaged in the ER following a motorvehicle accident. Extensive trauma to lower leg and ankle can be visualized in thetomosynthesis data set, despite the presence of a metal fixation splint. Sufficientinformation about the extent of the fractures and the location of the bone fragmentsenabled the surgeon to plan intervention without the need for CT imaging.

    Right: Postoperative follow-up after total hip replacement: (Left) tomosynthesisslice image (Right) CT MPR coronal image. The cranio-caudal tomosynthesis sweepprovides detailed information on potential loosening or peri-prosthetic fracturearound the femoral stem prosthesis, compared to the conventional radiograph andwith much less metallic artifact than CT. In the tomosynthesis image the minormetallic artifact appears as a low signal level or undershooting only along thesweep direction at the edges of the metallic prosthesis.

  • 24John. M. Sabol, Ph.D.

    AAPM 2012

  • 25John. M. Sabol, Ph.D.

    AAPM 2012

    Upper: Examples of improved visualization and characterization of bone erosions ina patient with rheumatoid arthritis.

    Lower Left: Example of a conventional PA radiograph and a slice from atomosynthesis dataset of a patient being image for assessment of kneeosteoarthritis. As seen on the tomosynthesis image, The patient has a bone chip inthe knee joint space. The bone chip is very difficult to detect on the conventionalimage.

    Lower Right: Conventional PA radiograph and a slice from a tomosynthesis datasetof a patient presenting with osteoarthritis. The extent of narrowing of the joint spaceis readily apparent on the tomosynthesis images.

  • 26John. M. Sabol, Ph.D.

    AAPM 2012

    With tomosynthesis imaging, it is possible to extract quantitative information aboutthe joint space. In this case, a semi-automatic algorithm has been developed byKalinosky et al to segment the edges of the femur and tibia and define the extent ofthe joint space in the knee. An example tomosynthesis slice image (Left) extractedjoint space width profile (center) and reconstructed 2-D map of the joint space (right)are shown for both PA (Upper) and Lateral (Lower) image acquisitions. The extractedjoint space profile are compared to values extracted from a CT dataset (center).

  • 27John. M. Sabol, Ph.D.

    AAPM 2012

  • 28John. M. Sabol, Ph.D.

    AAPM 2012

    Globally, IVP procedures with traditional x-ray is still a common procedure.Tomosynthesis replaces the need for linear tomography which is prone to fulcrumerrors and increased dose. Linear tomography is performed to determine size,location and shape of the kidneys and generally limited to a field of view of 10x12”.Tomosynthesis offers an increased FOV when needed, at the same dose as conedFOV’s. This patient has multiple areas of concern that were visualized in the full fieldFOV mode.

  • 29John. M. Sabol, Ph.D.

    AAPM 2012

    Individual slice images from previously shown patient.

    Slice 9 shows a kidney stone formation within the kidney. Slice 15 shows a Greenfieldfilter in the venacava used to trap blood clots from migrating to the lungs. Slice 18shows calcification in the Iliac arteries and distal aorta. Slice 22 shows gall stoneswithin the gall bladder.

  • 30John. M. Sabol, Ph.D.

    AAPM 2012

  • 31John. M. Sabol, Ph.D.

    AAPM 2012

  • 32John. M. Sabol, Ph.D.

    AAPM 2012

  • 33John. M. Sabol, Ph.D.

    AAPM 2012

    Modern digital tomosynthesis enables high resolution reconstruction of slice imagesthrough both TMJ joints after a single acquisition sweep.

  • 34John. M. Sabol, Ph.D.

    AAPM 2012

    Chronic maxillary sinusitis with obstruction of the natural ostia clearly visible on thetomosynthesis images (left). The complete obstruction of the patient’s rightmaxillary sinus can be seen, in comparison with the patent left sinus. Similar resultscan be seen on the much higher dose MDCT image (right).

  • 35John. M. Sabol, Ph.D.

    AAPM 2012

    Acute maxillary sinusitis as demonstrated on sinus tomosynthesis and MDCT MPRcoronal images. The tomosynthesis images (left) well delineates the air-fluid level inthe left maxillary sinus more easily and with less radiation dose than CT. Note thattomosynthesis enables imaging in both the upright and supine positions whichchanges the appearance of the air-fluid level, unlike in CT.

  • 36John. M. Sabol, Ph.D.

    AAPM 2012

  • 37John. M. Sabol, Ph.D.

    AAPM 2012

    Mandibular cyst imaged with both conventional mandibular radiography (left) andtomosynthesis (right). The tomosynthesis radiograph better delineates the cyst(arrows) as well as the mandibular canal than the conventional radiograph. Notethat there is minimal metallic artifact produced as a result of the dental fillings.

  • 38John. M. Sabol, Ph.D.

    AAPM 2012

    Example of a blow-out fracture on both tomosynthesis and CT MPR coronal images.The tomosynthesis image clearly delineates the fracture of the right orbital floor.Tomosynthesis offers easier imaging at less cost and radiation exposure than withCT. However, due to relatively lower contrast sensitivity, it is more difficult todifferentiate the content prolapsing into the maxillary sinus with tomosynthesisthan it is with CT. Note that the air-fluid level (arrowhead) resulting from thehemorrhage is visible in the right maxillary sinus in the tomosynthesis image due tothe upright position acquisition.

  • 39John. M. Sabol, Ph.D.

    AAPM 2012

  • 40John. M. Sabol, Ph.D.

    AAPM 2012

    Left:Linear path of x-ray source changes SID, decreases relative exposure to the patientat extremes of the sweep

    Middle:Collimation is adjusted with projection angle. Dose area changes, excess dose is notdelivered to the patient. Relevant to possible organ-specific dose effects at differentviews

    Right:mAs or dose may be changed as a function of view angle. Total tomosynthesis mAsis often expressed as a ratio of the mAs for the standard projection view.

  • 41John. M. Sabol, Ph.D.

    AAPM 2012

    84 different techniques investigated

  • 42John. M. Sabol, Ph.D.

    AAPM 2012

  • 43John. M. Sabol, Ph.D.

    AAPM 2012

  • 44John. M. Sabol, Ph.D.

    AAPM 2012

    The minimum exposure duration and finite mAs increments can prevent thetomosynthesis system from delivering the desired exposure for all desired exposuretechniques. This results in a lower dose to the patient for most techniques. However,for some techniques, specifically those of high kVp and minimal filtration, thetomosynthesis systems can deliver higher exposures than desired. Similarly, thedesired exposures corresponding to very low dose ratios will not routinely bedelivered by the system.

  • 45John. M. Sabol, Ph.D.

    AAPM 2012

    Examples of images from thoracic tuberculosis cases shown previously withestimated effective dose for each acquisition. The tomosynthesis images (center andright) were acquired with different techniques demonstrating significant changes indose possible with tomosynthesis. Further research into the optimization is requiredto determine the dose required for different tomosynthesis exams.

  • 46John. M. Sabol, Ph.D.

    AAPM 2012

  • 47John. M. Sabol, Ph.D.

    AAPM 2012

  • 48John. M. Sabol, Ph.D.

    AAPM 2012

  • 49John. M. Sabol, Ph.D.

    AAPM 2012

  • 50John. M. Sabol, Ph.D.

    AAPM 2012

  • 51John. M. Sabol, Ph.D.

    AAPM 2012

  • 52John. M. Sabol, Ph.D.

    AAPM 2012