COLLEGE  OF  AGRICULTURE  

AND  LIFE  SCIENCES  Department  of  Plant  Pathology  and  Microbiology  

 

120  Peterson  Bldg                                                                                                  2132  TAMU                                                                                                                                                                                                                        College  Station,  TX  77843-­2132    Tel.  979.845.7311          Fax.  979-­845-­6483  http://plantpathology.tamu.edu                          

To: David Reed, Professor and Associate Dean and the COALS GPC From: Heather H. Wilkinson, Professor and Associated Department Head

Re: Request to have Kranthi Kiran Mandadi instated as a member of the Graduate Faculty Attached: Mandadi CV, Graduate Faculty Personal Record Form

Position Title: Assistant Professor

a)   Highest Degree: Please consider Dr. Mandadi for inclusion in the graduate faculty. Dr. Mandadi received his PhD in 2010 from the Molecular and Environmental Plant Sciences Program at Texas A&M.

b)   Dr Mandadi has served as a Special Appointment member on the committee of Zachary Gorman, TAMU, PhD, in our department for close to a year.

c)   Referreed publications: Kranthi has 9 first author publications, 20 publications total (2007-2015). The most recent first author publication was: Mandadi, K.K., Pyle, J.D., and Scholthof, K-B.G. (2015) Characterization of SCL33 splicing patterns during diverse virus infections in Brachypodium distachyon. Plant Signal. Behav. 10:8, e1042641.

d)   Employer and location: Texas A&M AgriLife Research & Extension Center, 2415 East Hwy. 83, Weslaco, TX 78596, hired in January 2015

Mandadi, CV 2015, p.1

KRANTHI KIRAN MANDADI

Plant Pathology and Microbiology Office: +1 (956) 969-5634 Texas A&M AgriLife Research Cell: +1 (979) 319-1746 2415 E Highway 83 Fax: +1 (956) 969-5620 Weslaco, TX 78596 E-mail: kkmandadi@tamu.edu ____________________________________________________________________________________ PROFESSIONAL APPOINTMENTS AND EDUCATION 2015-Current Assistant Professor, Plant Pathology and Microbiology, Texas A&M AgriLife Research 2010-2014 Postdoctoral Research Associate, Texas A&M University 2005-2010 Ph.D., Molecular and Environmental Plant Sciences, Texas A&M University 2003-2005 M.S., Plant and Soil Sciences, Texas A&M University-Kingsville

1998-2002 B.S., Agricultural Sciences, ANGR Agricultural University, Hyderabad, India ____________________________________________________________________________________ PUBLICATIONS 23) Mandadi, K.K., Lyons, C.W., and Scholthof, K-B.G. Systems modeling of plant-virus interactions in the post-genomics era. (In preparation for Annu. Rev. Phytopath.) 22) Mandadi, K.K., Christensen, S., Schmelz, E., and Scholthof, K-B.G. Panicum mosaic virus

modulates ROS homeostasis, defense hormone signaling and fatty-acid profiles in Brachypodium distachyon (In preparation for Plant Physiol.)

21) Mandadi, K.K., Misra, A., and McKnight, T.D. BT2, a presumed component of CULLIN3-based ubiquitin ligase, is required for Cauliflower mosaic virus 35S enhancer mediated gene expression in Arabidopsis. (In preparation for Proc. Natl. Acad. Sci., USA)

20) Misra A., Mandadi, K.K., and McKnight, T.D. Bromodomain proteins GTE9 and GTE11 are essential for BT2-mediated responses to sugars and ABA in Arabidopsis thaliana. Plant Physiol. (Submitted)

19) Mandadi, K.K. and Scholthof, K-B.G. (2015) Genome-wide analysis of alternative splicing landscapes modulated during plant-virus interactions in Brachypodium distachyon Plant Cell 27, 71-85. FEATURED COVER/LARGE SCALE BIOLOGY 18) Mandadi K.K., Pyle, J.D., and Scholthof, K-B.G. (2014) Comparative analysis of antiviral responses

in Brachypodium distachyon and Setaria viridis reveal conserved and unique outcomes among C3 and C4 plant defenses. Mol. Plant Microbe Interact. 27, 1277-1290.

17) Mandadi, K.K., and Scholthof, K-B.G. (2013) Plant immune responses against viruses: How does a virus cause disease? Plant Cell 25, 1489–1505

16) Góngora-Castillo, E., Childs, K.L., Fedewa, G., Hamilton, J.P., Liscombe, D.K., Magallanes, M., Mandadi, K., Nims, N.E., Runguphan, W., Vaillancourt, B., Varbanova, M., DellaPenna, D., McKnight, T., O’Connor, S., and Buell, C.R. (2012). Development of transcriptomic resources for interrogating the biosynthesis of monoterpene indole alkaloids in medicinal plant species. PLoS ONE 7(12): e52506

15) Mandadi, K.K., and Scholthof, K.-B.G. (2012). Characterization of a viral synergism in the monocot Brachypodium reveals distinctly altered host molecular processes associated with disease. Plant Physiol. 160, 1432-1452.

14) Mandadi, K.K., Misra, A., Ren, S., and McKnight, T.D. (2009) BT2 mediates multiple responses to nutrients, stresses and hormones in Arabidopsis thaliana. Plant Physiol. 150, 1930-1939.

13) Ren, S., Mandadi, K.K., Boedeker, A.L., Rathore, K.S., and McKnight, T.D. (2007) Regulation of telomerase in Arabidopsis by BT2, an apparent target of the TELOMERASE ACTIVATOR1. Plant Cell 19, 23-31.

Mandadi, CV 2015, p.2

12) Mandadi, K., Ramirez, M., Jayaprakasha, G.K., Faraji, B., Lihono, M., Deyhim, F., and Patil B.S. (2009) Citrus bioactive compounds improve bone quality and plasma antioxidant activity in orchidectomized rats. Phytomedicine 16(6-7), 513-520.

11) Deyhim, F., Mandadi, K., Faraji, B and Patil B.S. (2008) Grapefruit juice modulates bone quality in rats. J. Med. Food 11, 99-104.

10) Deyhim, F., Mandadi, K., Faraji, B and Patil B.S. (2008) Grapefruit pulp increases antioxidant status and improves bone quality in orchidectomized rats. Nutrition 24, 1039-1044.

09) Jayaprakasha, G.K., Mandadi, K.K., Poulose, S.M., Jadegoud, Y., Nagana Gowda, G.A., and Patil, B.S. (2008) Novel triterpinoid from Citrus aurantium L. possess chemopreventive properties against human colon cancer cells. Bioorg. Med. Chem. 16, 5939-5951.

08) Deyhim, F., Villarreal, A., Garcia, K., Rios, R., Garcia, C., Gonzales, C., Mandadi, K., and Patil, B.S. (2007) Orange pulp improves antioxidant status and suppresses lipid peroxidation in orchidectomized male rats. Nutrition 23, 617-621.

07) Mandadi, K.K., Jayaprakasha, G.K., Bhat, N., and Patil, B.S. (2007) Red Mexican Grapefruit: A novel source for bioactive limonoids and their antioxidant activity. Z. Naturforschung 62C, 179.

06) Jayaprakasha, G.K., Mandadi, K.K., Poulose, S.M., Jadegoud, Y., Nagana Gowda, G.A., and Patil, B.S. (2007) Inhibition of colon cancer cell growth and antioxidant activity of bioactive compounds from Poncirus trifoliata (L.) Raf. Bioorg. Med. Chem. 15, 4923-4932.

05) Villarreal, A., Stoecker, B.J., Garcia, C., Garcia, K., Rios, R., Gonzales, C., Mandadi, K., Faraji, B., Patil, B.S., and Deyhim, F. (2007) Cranberry juice improved antioxidant status without affecting bone quality in orchidectomized male rats. Phytomedicine 10, 49-53.

04) Deyhim, F., Rios, R., Garcia, C., Villarreal, A., Garcia, K., Gonzales, C., Mandadi, K., Faraji, B., and Patil, B.S. (2007) Orange pulp increases antioxidant status and improves bone quality in orchidectomized rats. Curr. Nutr. Food Sci. 3, 319-323.

03) Deyhim, F., Garcia, C., Villarreal, A., Garcia, K., Rios, R., Gonzales, C., Mandadi, K., Faraji, B., and Patil, B.S. (2007) Vitamin E does not support bone quality in orchidectomized rats. Curr. Nutr. Food Sci. 3, 300-303.

02) Deyhim, F., Gonzales, C., Villarreal, A., Garcia, K., Rios, R., Garcia, C., Mandadi, K., and Patil, B.S. (2007) Vitamin E does not modulate plasma cholesterol, triglyceride, or C-reactive protein despite suppressing oxidative stress in orchidectomized rats. J. Med. Food 10, 559-562.

01) Deyhim, F., Patil, B.S., Villarreal, A., Lopez, E., Garcia, K., Rios, R., Garcia, C., Gonzales, C., and Mandadi, K. (2007) Cranberry juice increases antioxidant status without affecting cholesterol homeostasis in orchidectomized rats. J. Med. Food 10, 49-53.

____________________________________________________________________________________ CONFERENCE PRESENTATIONS Invited talks 2014 Mandadi, KK, Pyle, JP, and Scholthof, K-BG. Comparative viromic analyses of C3 and

C4 grass antiviral defense responses in Brachypodium distachyon and Setaria viridis. ‘Genomics mini-symposium’ American Society of Plant Biologists, July 12-16, Portland.

2014 Mandadi, KK, and Scholthof, K-BG. Transcriptomic analyses and alternative splicing landscapes of Brachypodium infected with Panicum mosaic virus. ‘Genomics session’, Plant and Animal Genome XXII. January 11-15, San Diego, CA.

2013 Lyons, C.W., Mandadi, KK, and Scholthof, K-B. G. Subcellular localization of Panicum mosaic virus proteins reflects the altered host transcriptional profiles in Brachypodium distachyon. American Phytopathological Society Meeting, August 10-14, Austin, TX.

2012 Mandadi, KK. Viral synergistic interactions of Panicum mosaic virus and its satellite virus (SPMV) in Brachypodium distachyon, a novel monocot research model. Dept. Seminar Series, April 11. Plant Pathology and Microbiology, Texas A&M University, College Station, TX

2012 Mandadi, K.K. and Scholthof, K.-B.G. Defining a synergism: Transcriptome analysis of the mixed infection of Panicum mosaic virus and its satellite virus (SPMV) in

Mandadi, CV 2015, p.3

Brachypodium distachyon. 21st Annual Plant Virology Retreat, May 4-6, The Samuel Roberts Noble Foundation, Ardmore, OK

2011 Mandadi, KK. BT2, a presumed component of an ubiquitin ligase, is required for Cauliflower mosaic virus 35S enhancer mediated activation of gene expression in Arabidopsis thaliana. 20th Annual Plant Virology Retreat, April 29- May 1, The Samuel Roberts Noble Foundation, Ardmore, OK

2010 Mandadi, KK. Multiple roles of BT2 in plant growth and development Postdoctoral Research Seminar Series, December 3. Plant Pathology and Microbiology, Texas A&M University, College Station, TX

Poster presentations (19, since 2004) ____________________________________________________________________________________ PATENTS 2015 Mirkov, T.E and Mandadi, K.K. “Novel synthetic expression cassettes encoding spinach

defensins to created disease resistant transgenic plants.” Provisional patent (in preparation) 2014 Mirkov, T.E and Mandadi, K.K. “Novel synthetic expression cassettes encoding spinach

defensins to create disease resistant transgenic plants.” Invention disclosure (TAMUS-4021) ____________________________________________________________________________________ GRADUAT AND UNDERGRADUATE MENTORING AND TEACHING Mentoring 2012-current Mr. Will Cody, Ph.D., Plant Path. & Microbiol., Texas A&M University 2013-current Mr. Jesse Pyle, M.S., Plant Path. & Microbiol., Texas A&M University 2015-current Ms. Ashley Jacques, BS, Biology (Pre-med), University of Texas-Pan American 2010-2014 Mr. Christopher Lyons, Ph.D., Plant Path. & Microbiol., Texas A&M University 2013-2014 Ms. Catherine Stewart, M.S. (visiting), Plant Path., Univ. of Nebraska-Lincoln 2011-2013 Mr. Jesse Pyle, BS (BESC honors), Plant Path. & Microbiol., Texas A&M 2005-2006 Mr. Travis Morgan, BS, Biology, Texas A&M University Teaching 2012-2014 Guest Lecturer, Plant Pathology and Microbiology, Texas A&M University.

• Plant Virology (PLPA 620): Spring 2012 • Methods in Molecular Biology of Plant-Microbe Interact. (PLPA 616): Fall 2012,

2013, 2014 • Pathogens, the Environment and Society (BESC 314): Fall 2012, 2013, 2014 • Introduction to Bioenvironmental Sciences (BESC 201): Spring 2013

2007-2010 Graduate Teaching Assistant (8 semesters), Biology, Texas A&M University. • Introductory Biology (BIOL 111): Fall 2007, Spring 2008, Summer 2008, Fall

2009, Summer 2009, Spring 2010 • Cell Biology (BIOL 413): Spring 2009 • Molecular Tools in Biology (BIOL 689): Fall 2009.

2004 Graduate Teaching Assistant (1 semester), Citrus Center, Texas A&M-Kingsville • Citrus & Subtropical fruits (HORT422): Fall 2004

____________________________________________________________________________________ GRANTS AND PROPOSALS 2013, 2015 American Society for Plant Biology competitive travel award (Funded: $725) 2011 Applicant for Life Science Research Foundation Minigrant and Fellowship, Princeton,

NJ. Project: Role of Nuclear and Nucleolar Trafficking of Viral Proteins. ($180,000) 2010 Graduate Student Council competitive travel award. (Funded: $500) 2010 MEPS competitive travel award (Funded: $500) 2009 American Society for Plant Biology competitive travel award. (Funded: $725)

Mandadi, CV 2015, p.4

2009 International Education Fee Study Grant, Texas A&M Univ. Project: Role of BT2 in plant stress responses. (Funded: $500)

2008 United States Geological Survey Research Grant. Project: Mitigating demand for irrigated water used in agriculture by genetically enhancing crop plants to be productive in minimal water conditions. (Funded, $5,000)

2009 Shibata Scholarship. Outstanding campus/community services involving leadership. (Funded $500)

2009 Academic Excellence Award. Texas A&M University, College Station (Funded: $4200) 2009 International Education Fee Scholarship for outstanding academic achievements.

(Funded: $1000) 2007 Mills Research Award. Project: Improving crop species for their drought tolerance and

water use efficiency capabilities. (Funded $1,500) 2005 Pathways to Doctorate Fellowship. Grantor- Office of Graduate Studies, Texas A&M

University, College Station, TX. (Funded: $30,000) ____________________________________________________________________________________ SERVICE AND SCHOLARLY ACTIVITIES National Organizations 2012-2014 Committee Member, Membership Committee, American Society of Plant Biologists 2011-2014 Ambassador, American Society of Plant Biologists 2012-2013 Liaison and Mentor, Planting Science, Botanical Society of America University 2010, 2011 Judge, Student Research Week, Texas A&M Univ., College Station, TX 2009 Event-coordinator and judge (Cell biology), Texas Science Olympiad, Texas A&M 2008 Planning committee, 11th annual Student Research Week, Texas A&M Department 2012-2014 President, Postdoctoral Association, Dept. Plant Path. & Microbiol., Texas A&M 2013 Chair, iPlant computational tools & services workshop, Texas A&M University 2012 Chair, Mini-forum on Genomic, RNA sequencing and Microarray technologies, Dept. Plant Path. & Microbiol., Texas A&M University 2010 Organizing committee, MEPS Research Symposium, Texas A&M University 2009-2010 Treasurer, MEPS Student Association (MEPSSA), Texas A&M University 2007-2010 Member of MEPSSA, Texas A&M University, College Station, TX Journal Peer Review 2010-current Peer reviewer for Journals: Molecular Plant-Microbe Interactions, Molecular Plant Pathology, Plant Physiology,

Functional Plant Biology, Physiological and Molecular Plant Pathology, Journal of Medicinal Food, Nutrition and Dietetics, Food Chemistry, American Chemical Society Books, Natural Products Journal

____________________________________________________________________________________ HONORS AND AWARDS 2013 Postdoc of the year, Department of Plant Pathology and Microbiology, Texas A&M. 2012, 2013 Mentor, Planting Science, Botanical Society of America 2011 MEPS Student Association Service Award 2009 2nd prize for best oral presentation at the 12th Annual Student Research Week. 2008 1st prize for best poster presentation at the Annual MEPS Fall Symposium. ____________________________________________________________________________________ PROFESSIONAL MEMBERSHIPS 2008- current American Society of Plant Biologists 2009-2013 American Association for the Advancement of Science