Dariusz Leszczynski/STUK DRAFT May 23, 2005

Workshop

“Application of Proteomics and Transcriptomics in EMF Research”

October 30 - November 1, 2005

STUK- Radiation and Nuclear Safety Authority Laippatie 4, 00880 Helsinki, Finland

http://www.who.int/peh-emf/meetings/proteomics_helsinki05/en/

Scientific Committee

Dariusz Leszczynski - Chair STUK, Finland

Mike Repacholi WHO

Norbert Leitgeb EU Cost281

Gerd Friedrich FGF

Frank Prato URSI Commission K

Marty Meltz ICES

Franz Adlkofer VerUm Foundation

Sponsoring Organizations

WHO EMF Project, Geneva, Switzerland

STUK - Radiation and Nuclear Safety Authority, Helsinki, Finland

EU Action Cost281

Forschungsgemeinschaft Funk (FGF), Germany

URSI Commission K

International Committee on Electromagnetic Safety (ICES), USA

VerUm Foundation, Munich, Germany

Dariusz Leszczynski/STUK DRAFT May 23, 2005

Scientific Program of the Workshop

Day 1: Presentations by Experts in High-Throughput Screening Techniques

October 30, 2005, Sunday

8:50 - 9:00 Opening

Mike Repacholi & Dariusz Leszczynski

9:00 - 9:40 Keynote talk

Towards system level analysis of biological questions

Risto Renkonen, Biomedicum, University of Helsinki, Finland

9:40 - 10:00 discussion

10:00 - 10:40 Proteomics - HPLC & MS

Timothy Griffin Department of Biochemistry, Molecular Biology & Biophysics,

University of Minnesota, Minneapolis, MN, USA

10:40 - 11:00 discussion

11:00 - 11:30 Coffee & Tea

11:30 - 12:10 2DE as tool for proteomics studies and protein identification

by mass spectrometry

Brigitte Wittmann-Liebold WITA GmbH, Teltow/Berlin, Germany

12:10 - 12:30 discussion

12:30 - 13:10 Protein chips

Thomas Joos (D. Stoll; M. Templin) Department of Biochemistry, NMI - Natural & Medical Sciences Institute,

University of Tübingen, Reutlingen, Germany

13:10 - 13:30 discussion

13:30 - 14:30 Lunch

14:30 - 15:10 Gene expression - DNA chip/arrays

Dirk Koczan Proteome Center, University of Rostock, Germany

15:10 - 15:30 discussion

14:30 - 16:10 Understanding complex biological systems with metabolomics:

An overview

Roy Goodacre School of Chemistry, University of Manchester, UK

16:10 - 16:30 discussion

16:30 - 17:00 Coffee & Tea

Dariusz Leszczynski/STUK DRAFT May 23, 2005

17:00 - 17:40 Protein networks

J. Douglas Armstrong, Institute for Adaptive and Neural Computation, School of Informatics,

University of Edinburgh, Scotland, UK

17:40 - 18:00 discussion

18:00 - 18:40 Bioinformatics and data mining

Juha Saharinen Department of Molecular Medicine, National Public Health Institute,

Helsinki, Finland

18:40 - 19:00 discussion

23:00 - 23:00 Dinner for invited speakers (sponsored by NOKIA)

Day 2: Presentations by EMF Researchers using High-Throughput Screening Techniques

October 31, 2005, Monday

9:00 - 9:30 Use of transcriptomics and proteomics in EMF research:

Present status and future needs

Dariusz Leszczynski Functional Proteomics Group, Radiation Biology Laboratory,

STUK, Finland

9:30 - 9:45 discussion

9:45 - 10:15 2D gel-based proteomics: Application in EMF-treated human

glioma cells and future directions

Frank Witzmann Department of Cellular and Integrative Physiology,

Indiana University Med. Sch., Indianapolis, IN, USA

10:15 - 10:30 discussion

10:30 - 11:00 Title: TBA

Jim Metcalfe, Department of Biochemistry, University of Cambridge, Cambridge UK

11:00 - 11:15 discussion

11:15 - 11:45 Coffee & Tea

11:45 - 12:15 Application of genomic and proteomic approaches in studying

bioeffects of EMF

Zhengping Xu Bioelectromagnetics Laboratory, Zhejiang University Med. Sch.,

Hanghzou, China

12:15 - 12:30 discussion

Dariusz Leszczynski/STUK DRAFT May 23, 2005

12:30 - 13:00 Title: TBA

Martin Meltz University of Texas Health Science Center, San Antonio, TX, USA

13:00 - 13:15 discussion

13:15 - 14:15 Lunch

14:15 - 14:45 Title: TBA

Joseph Roti Roti Division of Biology &Biomedical Sciences,

Washington University Med. Sch., St. Louis, MO, USA

14:45 - 15:00 discussion

15:00 - 15:30 In vitro gene expression studies and their impact on high content

screening assays in EMF research

Christian Maercker Mannheim University of Applied Sciences, Mannheim/Heidelberg, Germany

15:30 - 15:45 discussion

15:45 - 16:15 The proteomic analysis of human endothelial cells exposed to mobile

phone radiation Reetta Nylund

Functional Proteomics Group, Radiation Biology Laboratory,

STUK, Finland

16:15 - 16:30 discussion

16:30 - 17:00 The proteomic response of S. pombe to static and oscillating low-field

strength EMFs

John Timms Ludwig Institute for Cancer Research, Proteomics Unit, London, UK

17:00 - 17:15 discussion

17:15 - 18:30 Brief 10 min. presentations from the submitted abstracts

18:30 - 20:00 Working groups preparing summary statements

Coffee & Tea will be served in the working rooms

20:00 - 23:00 Get-together event with snacks and wine

Day 3: Summaries & rapporteurs’ reports

November 1, 2005, Tuesday

9:00 - 9:30 Statement proposals

9:30 - 11:00 Discussion on statements (Moderator: TBA)

11:00 - 11:30 Coffee & Tea

Dariusz Leszczynski/STUK DRAFT May 23, 2005

11:30 - 12:00 The first draft of the workshop rapporteurs’ report (Leszczynski & Meltz)

12:00 - 13:00 General discussion (Moderator: Michael Repacholi)

13:00 - departure (on your own)