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Assessment of the Neonate
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5/23/2013
Copyright 2008 AP Jones 1
Assessment of the Neonate
Arthur Jones, EdD, RRT
http://rc-edconsultant.com/
Learning objective:
Interpret findings from physical andphysiological assessments of thenewborn.
Neonatal
Scoring Systems
FYI - Click for article on use and abuse of Apgar scorehttp://pediatrics.aappublications.org/cgi/content/abstract/pediatrics;98/1/141
Apgar score
Rated at one and five minutes
Intended only to assess generalcondition
Does not:
define asphyxia
predict future development
influence Ivy League admission
Health premature infants willlikely have low Apgar scores
Apgar scoring system
ƒObservations
Color - skin colorimetry reflectsillness severity
Heart rate
Reflex activity
Activity
Respirations
0 1 2
Color centralcyanosis
peripheralcyanosis
pink
Apgar scoring system
5/23/2013
Copyright 2008 AP Jones 2
0 1 2
Color centralcyanosis
peripheralcyanosis
pink
Heart rate nonedetectable
<100 >100
Apgar scoring system0 1 2
Color centralcyanosis
peripheralcyanosis
pink
Heart rate nonedetectable
<100 >100
Respiratoryeffort
apnea irregular,shallow
crying
Apgar scoring system
0 1 2
Color centralcyanosis
peripheralcyanosis
pink
Heart rate nonedetectable
<100 >100
Respiratoryeffort
apnea irregular,shallow
crying
Reflex none grimace(withdraw)
crying
Apgar scoring system0 1 2
Color centralcyanosis
peripheralcyanosis
pink
Heart rate nonedetectable
<100 >100
Respiratoryeffort
apnea irregular,shallow
crying
Reflex none grimace(withdraw)
crying
Muscle tone(activity)
flaccid someflexion
well-flexed
Apgar scoring system
Gestational age estimation
Prenatal
menstrual cycle - 1st day of lastmenstrual period + 280 days
fundal height measurement -mom's abdomen
ultrasound
Gestational age estimation
Postnatal
ultrasound measurement - femurlength
Ballard score - AKA Ballard-Dubowitz score
5/23/2013
Copyright 2008 AP Jones 3
Ballard score
ƒEstimation of gestational age
ƒPhysical signs
Skin
Breast
Lanugo
Eye/ear
Plantar surface
Genitalia
FYI - Click to view/bookmark Ballard Score videoshttp://www.ballardscore.com/Pages/videos.aspx
Gestational age/score
24-26 wkscore = 0
35-40 wkscore = 4
Skin gelatinous,red, translucent
parchment, deepcracks, no visiblevessels
Ballard score - physical signs
Gestational age/score
24-26 wkscore = 0
35-40 wkscore = 4
Skin gelatinous,red, translucent
parchment, deepcracks, no visiblevessels
Lanugo none to sparse none to sparse
Ballard score - physical signsGestational age/score
24-26 wkscore = 0
35-40 wkscore = 4
Skin gelatinous,red, translucent
parchment, deepcracks, no visiblevessels
Lanugo sparse mostly bald
Plantarsurface
no crease creases over entiresole
Ballard score - physical signs
Click to see skin scoringhttp://www.ballardscore.com/Pages/mono_phys_skin.aspx
Click to see lanugo scoringhttp://www.ballardscore.com/Pages/mono_phys_lanugo.aspx
Click to see plantar surface scoringhttp://www.ballardscore.com/Pages/mono_phys_plantar.aspx
Gestational age/score
24-26 wkscore = 0
35-40 wkscore = 4
Skin gelatinous,red, translucent
parchment, deepcracks, no visiblevessels
Lanugo sparse mostly bald
Plantarsurface
no crease creases over entiresole
Breast barely perceptible full areolae; 5-10 mmbud
Ballard score - physical signs
Click to see breast scoringhttp://www.ballardscore.com/Pages/mono_phys_breast.aspx
Gestational age/score
24-26 wkscore = 0
35-40 wkscore = 4
Skin gelatinous,red, translucent
parchment, deepcracks, no visiblevessels
Lanugo sparse mostly bald
Plantarsurface
no crease creases over entiresole
Breast barely perceptible full areolae; 5-10 mmbud
Eye and ear lids open, pinna flat& stays folded
eyes open, ear thickcartilage, stiff
Ballard score - physical signs
Click to see eye & ear scoringhttp://www.ballardscore.com/Pages/mono_phys_eyear.aspx
5/23/2013
Copyright 2008 AP Jones 4
Gestational age/score
24-26 wkscore = 0
35-40 wkscore = 4
Genitalia- male scrotum empty,faint rugae
testes pendulousdeep rugae
Genitalia-female prominent clitorissmall labia minora
majora cover clitorisand minora
Ballard score - physical signs
Click to see male genitalia scoringhttp://www.ballardscore.com/Pages/mono_phys_male.aspx
Click to see female genitalia scoringhttp://www.ballardscore.com/Pages/mono_phys_female.aspx
FYI - Click for pictures of ambiguous genitaliahttp://lh4.ggpht.com/-u5SwxozUhSk/SR8VWtH-RBI/AAAAAAAAD4I/E6eD7RW7vpQ/DSC00229.JPG
Ballard score - neuromuscular signs
ƒPosture
degree of extremity flexion
greater flexion ==> maturity
ƒSquare window
flexion of hand to forearm
greater flexion ==> maturity
Click to see posture scoring
http://www.ballardscore.com/mono_neuro_posture.htm
Click to see square window scoring
http://www.ballardscore.com/mono_neuro_squarewindow.htm
Ballard score- neuromuscular signs
ƒArm recoil
recoil of arm after full extension
full recoil ==> maturity
ƒPopliteal angle
angle of knee, with thigh on chest
lesser angle ==> maturity
Click to see arm recoil scoring
http://www.ballardscore.com/mono_neuro_armrecoil.htm
Click to see popliteal angle scoring
http://www.ballardscore.com/mono_neuro_pop.htm
Ballard score- neuromuscular signs
ƒScarf sign
put hand on opposite shoulder
lesser travel of elbow across midline==> maturity
ƒHeel-to-ear
non-forceful movement of heel to ear
greater distance heel - ear ==>mature
Click to see scarf sign scoring
http://www.ballardscore.com/mono_neuro_scarf.htm
Click to see heel-to-ear scoring
http://www.ballardscore.com/mono_neuro_heel.htm
Ballard scoring
ƒMaturity ratings
0 24 weeks
10 28 weeks
20 32 weeks
30 36 weeks
40 40 weeks
50 44 weeks
Click to see the Ballard score calculatorhttp://www.medcalc.com/ballard.html
Acute illness scoring
Purposes
to predict mortality
guide patient management
set standards for research,benchmarking across institutions
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Copyright 2008 AP Jones 5
Acute illness scoring
Score systems
Score for neonatal acutephysiology (SNAP II)
Clinical risk index for babies
(CRIB II)
oxygenation index (later section)
Validity - CRIB II may be morediscriminatory
Scoring systems are not very goodat predicting mortality
Acute illness scoring
Parameters SNAP II
mean blood pressure
lowest temperature
PO2/FIO2%
lowest pH
multiple seizures
urine output
Apgar score
birth weight
small for gestational age
Acute illness scoring
Parameters CRIB II
gender
gestation weeks
birthweight
admission temperature
base excess
FYI - Click to see SNAP II score calculator
http://www.sfar.org/scores2/snap22.html
FYI - Click to see CRIB II score calculator
http://www.sfar.org/scores2/crib22.html
Normal physical features
ƒLanugo - fine hair
ƒPeripheral cyanosis - due to reduced
peripheral perfusion
ƒVernix caseosa - white coating
ƒFontanelles - anterior, posterior
Normal physical features
ƒLanugo - fine hair
ƒPeripheral cyanosis - due to reduced
peripheral perfusion
ƒVernix caseosa - white coating
ƒFontanelles - anterior, posterior
ƒPhysiologic jaundice - > 24 hrs
postpartum
ƒTelangiectatic nevi - "stork bites"
ƒMinimal ecchymoses & petechiae
Click to see stork bitehttp://pregnancy.about.com/od/newbornbabies/ig/Newborn-Photo-Gallery/Stork-Bite---Newborn.htm
Normal physical features
ƒRespirations
normal RR = 30-60/min
auscultation ==> sounds transmitted
easily across small chest
periodic breathing - apnea < 10 sec
ƒnormal in preterm newborns
ƒnon-pathologic
apnea of prematurity - apnea > 10Sec
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Copyright 2008 AP Jones 6
Silverman Respiratory Status Index
ƒPurpose - objectively scorephysical evidence of increasedwork of breathing (WOB)
ƒFive observations, scored 0-2
ƒHigher score ==> greater WOB
(maximum score = 10)
Silverman Respiratory Status Index
ƒParameters
Synchrony of upper & lower chest -
seesawing = 2
Nasal flaring - marked = 2
Lower chest retractions = marked
intercostal retractions = 2
Xiphoid retractions - markedretraction of skin over xiphoid = 2
Expiratory grunt - audible to ear = 2
Click to see Downes and Silverman scoring systems
http://members.tripod.com/puffnicu/rd.html
Cardiovascular assessment
ƒHR = 120 - 160 /min
ƒBP (term infant) = 50-70/25-50
ƒumbilical stump- 2 arteries, 1 vein
Click for more informatino on neonatal blood pressurehttp://www.netsvic.org.au/nets/handbook/index.cfm?doc_id=450
Click to see umbilical stumphttp://www.biosci.ohiou.edu/introbioslab/Bios171/images/lab5/umb_cord2.jpg
Cardiovascular assessment
ƒauscultation for murmurs - turbulent
blood flow across valves
abnormal valves
abnormal vessels
septal defects
ƒbrachial pulses compared to femoralfor equal intensity - unequal ==>aortic coarctatation
FYI - click for website with heart murmurs (bookmark?)
http://www.wilkes.med.ucla.edu/inex.htm
Click for more information and pictures of coarctation
http://www.pted.org/?id=coarctation1
Neurologic responses (reflexes)
ƒGrasp- grasps with hand
ƒSuck - starts early, in utero
ƒRooting - turns head to suck
ƒMoro - startle reflex
ƒBabinski - normal newborn toescurl upward
Click for video of neonatal reflex evaluation (2.5 min.)
http://www.youtube.com/watch?v=gyVLD0hl0XY&feature=related
Abnormal features
ƒMeconium stains - aspiration
ƒFlaring, grunting, retractions
ƒCentral cyanosis - hypoxemia
ƒJaundice < 24 H postpartum
color due to bilirubin
causes: hemolysis, liver failure
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Copyright 2008 AP Jones 7
Abnormal features
ƒFontanelles - anterior and posterior
bulging ==> increased ICP
sunken ==> dehydration
ƒUpper extremity immobility
Broken clavicles
Brachial plexus injury
Click to see radiograph of birth trauma (clavicle)
http://niyaf.com/post/31434342/birth-trauma-fractured-clavicle-collar-bone
Click to see a picture of birth trauma (forceps marks)http://pregnancy.about.com/od/newbornbabies/ig/Newborn-Photo-Gallery/Newborn-with-Forcep-Marks.htm
Abnormal features
ƒFacies
ƒmicrognathia (small mandible)
ƒPierre-Robin syndrome
ƒTreacher Collins syndrome
ƒmicrostomia (small mouth) -
trisomy 18
ƒcleft lip, palate
Click to see image of micrognathiahttp://www.mdconsult.com/das/pdxmd/media/1206/6120625/large.jpg
Click to see image of microstomiahttp://www.nndb.com/people/905/000091632/joeebrown02.jpg
Abnormal features
ƒCri-du-chat (cat's cry) - deletion ofpartial chromosome (normal in felinenewborns)
ƒSimian crease - single palmar crease
ƒpresent in some normal infants
ƒcommon in trisomy 21 (Downsyndrome)
ƒcommon in cri-du-chat
Click to see image of simian creasehttp://www.nlm.nih.gov/medlineplus/ency/images/ency/fullsize/17226.jpg
Click to hear cri-du-chathttp://fs6.depauw.edu:50080/~cfornari/DISGEN/CriDuChat%20Website/images/babycryb.wav
FYI - Click for Atlas of congenital anomalieshttp://www.gfmer.ch/genetic_diseases_v2/index.php?disinit=L
Abnormal features
ƒPolydactyly - sometimes associatedwith lethal anomalies
ƒLethal anomalies - lethal; but,when?
cystic fibrosis (Caucasians)
sickle cell anemia (African)
trisomy 13 (Patau syndrome)
trisomy 18 (Edwards syndrome)FYI - Click for video about cri-du-chat (4.5 min.)http://www.youtube.com/watch?v=pxh9m1dTU0Q
FYI - Click for picture of anencephalyhttp://isc.temple.edu/neuroanatomy/lab/embryo_new/nt/4/anen.html
Abnormal features
ƒLethal anomalies
inoperable cardiac anomalies(acardia)
Potter's syndrome
pulmonary hypoplasia -undeveloped lung(s)
renal agenesis
anencephaly
lethal white disease (horses)
Abnormal features
ƒLethal anomalies - ethical & legalissues
futility of efforts
allocation of resources
end-of-life care for parents
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Copyright 2008 AP Jones 8
Abnormal features
ƒGastroschisis - externalized,
uncovered bowel
ƒOmphalocoele
bowel covered with peritoneum
associated with other anomalies
ƒSpina bifida - exposed spinal cord
ƒHydrocephaly - cerebral edemaClick to see picture of gastroschisishttp://www.medword.net/images/clinical/omphalocele/flut041216d_001.jpg
Click to see picture of hydrocephalyhttp://www.flickr.com/photos/hydroassoc/2073488415/
Click to see picture of spina bifidahttp://www.scienceclarified.com/images/uesc_02_img0090.jpg
Physiologic features
ƒLung mechanics
ƒTV = 7 mL/kg
ƒFRC = 21 mL/kg
ƒVD = 5 mL/kg
ƒRespiratory system compliance
ƒterm newborn..........5 mL/cm H2O
ƒpreterm newborn....3 mL/cm H2O
ƒadult.........................100 mL/cm H2O
Physiologic features
ƒLung mechanics
ƒhigh chest wall compliance ==>
decreased support of lung expansion
by chest wall
thoracic retractions- early sign of
distress
Click for video of retractions (.25)
http://www.youtube.com/watch?v=sgJNTnhf8v0&feature=related
Physiologic features
ƒAirway resistance
ƒterm newborn..........70 cm H2O/L/sec
ƒpreterm newborn.....97 cm H2O/L/sec
ƒadult..........................2.5 cm H2O/L/sec
ƒInspiratory flow
ƒterm newborn...........3-6 L/min
ƒadult...........................30-60 L/min
Blood gases
ƒSample sources
ƒumbilical cord - partum
ƒumbilical artery catheter
ƒperipheral artery; e.g., brachial
ƒvein - pH and PCO2 only
ƒcapillary
ƒpainful for patient
ƒpH and PCO2 only
ƒunreliable if patient is in shock
Blood gases
ƒHypoxia sources
ƒhypoxemia (decreased PO2,SPO2)
ƒanatomic shunts
ƒpulmonary shunts
ƒanemia - includes
ƒHbCO from maternal smoking
ƒHbMET from nitric oxide (NO)
ƒcirculatory
ƒanatomic shunts
ƒshock
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Copyright 2008 AP Jones 9
Blood gases
ƒAcid-base disturbances
ƒrespiratory acidemia
ƒrespiratory alkalemia
ƒmetabolic acidemia
ƒshock, sepsis
ƒdiarrhea - loss of bicarbonate
ƒmetabolic disorders; e.g., diabetes
ƒmetabolic alkalemia
ƒdiuretics
ƒgastric suctioning
Umbilical arterial gas sea level norms
20 min 1 hour 4 hours
pH 7.35 7.40 7.40
PaCO2 35 30 35
PaO2 50-65 50-65 65-70
Note: shift in HbO2 curve ==> infant
p50 = 21 mm Hg
Blood gases
Oxygenation index - calculatedscore
used for all patient groups
purposes:
ƒpredict outcomes
ƒguide management choices; e.g.,ECMO
ƒcompare outcomes amonginstitutions; e.g., for benchmarking
FYI - Click to download article on oxygenation index
http://ajrccm.atsjournals.org/cgi/reprint/172/2/206
Blood gases
Oxygenation index (OI)
advantage over other indexes -takes mean airway pressure intoaccount
oxygen index equation:
FYI - Click for oxygen index calculator
http://www.medcalc.com/oxygen.html
OI = FiO2 * MAP
PaO2
Pulse oximetry
Purposes:
adjust FIO2
ƒensure adequate oxygenation
ƒprevent hyperoxia
screening for ductal-dependentcardiac anomalies
perfusion index from signalamplitude reflects illness severity
Optimal range for SPO2 forinfants on O2 therapy = 85% - 93%
TOSCA monitor
Made by Linde Medical Sensors
Ear sensor with SPO2 andtranscutaneous PCO2 (PTCCO2)measurement
Found accurate and reliable byseveral studies
FYI - click to see abstract of study on TOSCAhttp://pediatrics.aappublications.org/cgi/content/abstract/peds.2004-0946v1
5/23/2013
Copyright 2008 AP Jones 10
Neonatal Blood
ƒfetal Hb
greater affinity for O2 than adult Hb- partial compensation for low fetalPaO2 (<29 mm Hg)
present, with adult Hb for 1st year
ƒinitial CBC (term)
Hb = 16.5 - compensation forPaO2
Hct = 50
WBC = 18,000
Neonatal Blood
ƒimmunoglobulins
IgG from mom while in utero
IgA from breast milk
newborn starts developing own IgG
post-natally
increased IgM at birth ==>
intrauterine infection
FYI - click for more information on immunoglobulinshttp://www.wellness.com/reference/allergies/newborn-immune-system
Weight/gestational age
Gestational age - extremely lowgestational age (ELGAN) - < 28 wks.
Weight/GA categories
ƒAppropriate for gestational age(AGA)
ƒSmall for gestational age (SGA)
ƒLarge for gestational age (LGA)
Infants who are SGA, show greatermortality, independent of gestationalage
Weight categories
Weight
Moderately low (MLBW).........1501-2500g
Very low (VLBW).....................1001-1500g
Extremely low (ELBW)..........<1000g
Review & Summary
ƒApgar score - general health
ƒBallard score - gestational age
ƒSilverman respiratory status index
ƒCritical care scores - CRIB, SNAPPE
Review & Summary
ƒNormal physical features
ƒAbnormal physical features
ƒNormal neurologic responses
ƒCardiovascular assessment
ƒNormal physiologic features
lung mechanics
blood gases, pulse oximetry
ƒWeight/gestational age relationships
5/23/2013
Copyright 2008 AP Jones 11
END
References
ƒJohnson KB, Oski FA. Oski's Essential Pediatrics 1997.Lippincott Publishers, Philadelphia. Chap. 11
ƒBarnhart SL, Czervinski MP. Perinatal and PediatricRespiratory Care 2nd Ed 2003. W.B. Saunders Company,Philadelphia. Chap. 3
ƒWhitaker KL. Comprehensive Perinatal & PediatricRespiratory Care (2nd ed.) 1996. Delmar Publishers,Albany. Chap 5.
ƒCommittee on fetus and newborn. Use and abuse of theApgar score. Pediatrics 1996;98:141-142.
ƒSasidharan K, Dutta S, Narang A. Validity of New BallardScore till 7th day of postnatal life in moderately pretermneonates. Arch Dis Child. 2008 Mar 12.
ƒDe Felice C, et al. Predictive value of skin color forillness severity in the high-risk newborn. PediatricResearch 2002;51:100-105.
References
ƒMackanjee HR, Iliescu BM, Dawson WB. Assessment ofpostnatal gestational age using sonographicmeasurements of femur length. J Ultrasound Med. 1996Feb;15(2):115-20.
ƒMeadow W, et al. Just, in time: ethical implications ofserial predictions of death and morbidity for ventilatedpremature infants. Pediatrics. 2008 Apr;121(4):732-40.
ƒGagliardi L, eta al. Assessing mortality risk in lowbirthweight infants: a comparison of CRIB, CRIB-II andSPAPPE-II. Arch Dis Child Fetal Neonatal Ed.2004;89:F419-F422.
ƒTrachsel D, McCrindle BW, Nakagawa S, Bohn D.Oxygenation index predicts outcome in children withacute hypoxemic respiratory failure. Am J Respir CritCare Med. 2005 Jul 15;172(2):206-11. Epub 2005 Apr 7.
ƒBrouillette RT, Waxman DH. Evaluation of the newborn'sblood gas status. Clin Chem 1997;43:215-221.
References
ƒHjalmarson O, Sandberg K. Abnormal lung function inhealthy preterm infants. Am J Respir Crit Care Med2002;165:83-87.
ƒCastillo A, et al. Pulse oxygen saturation levels andarterial oxygen tension values in newborns receivingoxygen therapy in the neonatal intensive care unit: is85% to 93% and acceptable range? Pediatrics2008;121:882-889.
ƒde Wahl, GA, et al. Impact of pulse oximetry screeningon the detection of duct dependent congenital heartdisease: a Swedish prospective screening study in39,821 newborns. BMJ. 2009 Jan 8;338:a3037.
ƒDe Felice C, Latini G, Vacca P, Kopotic RJ. The pulseoximeter perfusion index as a predictor for high illnessseverity in neonates.Eur J Pediatr. 2002;161(10):561-2.