BREAST CANCER OVERVIEW Polly Stephens, M.D.

BREAST ANATOMY

breastcancer.org

Ductal Carcinoma In Situ

Calcifications

CALCIFICATIONS

                                                                                                                   The 

Invasive Ductal Carcinoma

Breast cancer

Breast cancer

Vascular/Lymphatic Invasion

Bone scan

Liver metastases

MAMMOGRAPHY

In America, most breast cancers are diagnosed on mammogram

• 1st mammogram age 35 – Or 10 years before your mother was

diagnosed with breast cancer• Yearly starting age 40• About 10% of cancers are not seen on

mammogram. DO YOUR OWN EXAM

St Francis Cancer Institute

BIOPSY

• Ultrasound-guided• Stereotactic• MRI guided biopsy

STEREOTACTIC BIOPSY

ULTRASOUND BIOPSY

INVASIVE DUCTAL CARCINOMA

• Overall survival 75%• Stage

– 0 Ductal carcinoma in situ– I tumor <2cm, no lymph nodes– II tumor 2-5cm, <4 lymph nodes– III tumor >5cm, >4 lymph nodes– IV distant metastases

INFLAMMATORY BREAST CANCER

• P’eau d’orange

Treatment

• Local control– Lumpectomy/mastectomy– Radiation

• Distal control– Chemotherapy

Sentinel node biopsy

Mammosite

External Beam Radiation

Who needs chemotherapy?

• If there is a risk of cells in the blood stream looking for a place to settle– Bone, Liver, Lung, Brain

• There is no blood test for breast cancer cells in the blood stream

Genetics

• BRCA 1 and 2– Alterations or mutations in these genes

increase ones risk for breast and ovarian cancer

– Only about 5% of breast cancer patients are BRCA +