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China Natural Ingredients Industry Media 专业纸媒杂志 --------------------------------------------------------------------------------------------------------------------- China Natural ingredients Industry Media PartnerWebsitewww.herbridge.com Push Corporation and Innovation,Build natural health supply chainsContactGloria Zhang Tel18182608257 Xi’an13521674640BeijingE-Mail[email protected] [email protected] 1 China Natural Ingredients Express III catalogue Research ............................................................................................................................................ 2 Kunming Institute of Botany: schisandra triterpenoid increased brain derived neurotrophic factor expression ....................................................................................................................... 2 Resource............................................................................................................................................ 3 Immature bitter orange decrease in output, hesperidins price is unstable ................................. 3 5000 tons wolfberry signed in Ningxia .................................................................................. 4 Rugulation ......................................................................................................................................... 5 Interpretation of CFDA new rules: Personalized regulation of plant extracts industry is still far away..................................................................................................................................... 5 Ingredients......................................................................................................................................... 6 ginger price risesginger oil show good prspects ................................................................. 6 Industry ............................................................................................................................................. 8 China Herbal ingredients industry expect new revolution ........................................................ 8 Tribulus terrestris extract market keep stable.......................................................................... 10 Astaxanthin price goes up ....................................................................................................... 11 Salvia miltiorrhiza extract keep stable .................................................................................... 11 Herbridge survey: Silymarin market has increased steadily ................................................... 12 2014CPHI&FIA interview record by Herbridge Media .......................................................... 13 Nutrition Market & Trends ............................................................................................................. 16 2014 China's top ten beverage enterprises .............................................................................. 16 2014 the world's top ten enterprises ........................................................................................ 17 2014 China's top ten chocolate brands .................................................................................... 17 Conference news ............................................................................................................................. 18 China Natural Ingredients Conference 2014 will be held on 30th-31stOctoberIn Hangzhou City.......................................................................................................................................... 18

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Page 1: China Natural Ingredients Express III · China Natural ingredients Industry Media Partner! Website: Push Corporation and Innovation,Build natural health supply chains! Contact:Gloria

China Natural Ingredients Industry Media 专业纸媒杂志 ---------------------------------------------------------------------------------------------------------------------

China Natural ingredients Industry Media Partner! Website:www.herbridge.com Push Corporation and Innovation,Build natural health supply chains! Contact:Gloria Zhang Tel:18182608257 (Xi’an)13521674640(Beijing) E-Mail:[email protected][email protected]

1

China Natural Ingredients Express III

catalogue Research............................................................................................................................................2

Kunming Institute of Botany: schisandra triterpenoid increased brain derived neurotrophic factor expression .......................................................................................................................2

Resource............................................................................................................................................3 Immature bitter orange decrease in output, hesperidins price is unstable .................................3 5000 tons wolfberry signed in Ningxia ..................................................................................4

Rugulation.........................................................................................................................................5 Interpretation of CFDA new rules: Personalized regulation of plant extracts industry is still far away.....................................................................................................................................5

Ingredients.........................................................................................................................................6 ginger price rises, ginger oil show good prspects .................................................................6

Industry .............................................................................................................................................8 China Herbal ingredients industry expect new revolution ........................................................8 Tribulus terrestris extract market keep stable..........................................................................10 Astaxanthin price goes up .......................................................................................................11 Salvia miltiorrhiza extract keep stable ....................................................................................11 Herbridge survey: Silymarin market has increased steadily ...................................................12 2014CPHI&FIA interview record by Herbridge Media..........................................................13

Nutrition Market & Trends .............................................................................................................16 2014 China's top ten beverage enterprises ..............................................................................16 2014 the world's top ten enterprises ........................................................................................17 2014 China's top ten chocolate brands ....................................................................................17

Conference news.............................................................................................................................18 China Natural Ingredients Conference 2014 will be held on 30th-31st,October,In Hangzhou City..........................................................................................................................................18

Page 2: China Natural Ingredients Express III · China Natural ingredients Industry Media Partner! Website: Push Corporation and Innovation,Build natural health supply chains! Contact:Gloria

China Natural Ingredients Industry Media 专业纸媒杂志 ---------------------------------------------------------------------------------------------------------------------

China Natural ingredients Industry Media Partner! Website:www.herbridge.com Push Corporation and Innovation,Build natural health supply chains! Contact:Gloria Zhang Tel:18182608257 (Xi’an)13521674640(Beijing) E-Mail:[email protected][email protected]

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Research

Kunming Institute of Botany: schisandra triterpenoid

increased brain derived neurotrophic factor

expression

Schisandra chinensis as one of the famous traditional Chinese medicine have been used in China for thousands of years. S. neglecta, s. rubriflora and s. sphaerandra in folk as same as the function of s. chinensis, often used in the treatment of insomnia, eliminate fatigue, increase intelligence, and tranquilize mind, etc. Schisandra plant except compounds of containing abundant lignans, also contains variety of structure of triterpene compound, such as nigranoic acid, SBB1, etc., but are rarely reported in neuropharmacology. Calcium ions (Ca2 +) as a second messenger transform exogenous signals into intracellular signal, lead to a series of intracellular events and physiological reaction, such as gene expression, cell apoptosis, muscle contraction, etc. The studies have shown that the messenger function of Ca2 + is accomplished through regulating intracellular Ca2 + concentration. Recently, kunming institute of botany, Chinese academy of sciences Luo Huairong team and Sun Han dong team cooperation, the use of nerve cell line PC12 cells and found that schizandra triterpene compound neural pharmacology activity and its mechanism of action. The study found that SBB1 in time and dose dependent induced differentiation PC12 cells Ca2 + concentration increases, and SBB1 calcium flow effect is significant inhibition after remove the cell cultures Ca2 +. SBB1 can be produced nitric oxide (NO) after elevated intracellular Ca2 + concentration, and present Ca2 + dependencies. SBB1 by Ca2 + - calmodulin pathways activated cells regulate protein kinase ERK1/2 phosphorylation, and significantly enhanced expression of brain derived neurotrophic factor BDNF and immediate early genes c-fos gene. To sum up, its result found SBB1 may promote NO produced and stimulate ERK1/2 protein phosphorylation by calcium current, thereby further influence the expression of BDNF and c - fos gene. In nervous system diseases such as alzheimer's disease and depression, the expression level of BDNF in the brain is very low, and the c - fos gene’s expression level is closely related to learning-memory. The research results provide new ideas for biological activity research of schisandra triterpene compounds. The above research results have been titled to Effect of nigranoic acid on Ca2 + influx and its

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China Natural Ingredients Industry Media 专业纸媒杂志 ---------------------------------------------------------------------------------------------------------------------

China Natural ingredients Industry Media Partner! Website:www.herbridge.com Push Corporation and Innovation,Build natural health supply chains! Contact:Gloria Zhang Tel:18182608257 (Xi’an)13521674640(Beijing) E-Mail:[email protected][email protected]

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downstream signal mechanism in contraversy differentiated PC12 cells, and published online in the Journal of Ethnopharmacology (http://dx.doi.org/10.1016/j.jep.2014.03.038). The research work obtain the one hundred projects of the Chinese academy of sciences, national natural science fund project (81373290) and the fund projects in Yunnan province(20080A007and 2012FB178) sponsorship.

Resource

Immature bitter orange decrease in output,

hesperidins price is unstable

The acquisition and use of immature bitter orange extract in normal years is about 4000-6000 tons before the new production from 2012 to 2014, according Herbridge Media. There is only 1500 tons immature bitter orange to meet market demand in 2014. Due to immature bitter orange plant production surplus in 2011, its supply is sharply in 2012, and rainfall during the production of new will inevitably make immature bitter orange price increasing. Immature bitter orange market supply has been stable in 2013. By 2014, rainfall again during new production has affected the production; make the supply of immature bitter orange further tightening. Enterprise viewpoint: Hesperidins market affected by the production cuts of immature bitter orange The main supply area of synephrine, diosmin, neohesperidin, neohesperidin dihydrochalcone and citrus bioflavonoid is concentrated in Sichuan Province, according to the information. Through the development of recent years, there are covered in Hunan, Zhejiang and Shaanxi Province. synephrine, diosmin, neohesperidin, neohesperidin dihydrochalcone market price floating is modest, due to limited market demand. The international market demand of citrus bioflavonoid has increased, but the market prices haven't changed much. Hesperidin influenced obviously, the market price of it also rose in May this year. Hesperidin market demand is so tight that attributed to the current international and China’s national conditions. The trend growth of three high and the aging of the population make the

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China Natural ingredients Industry Media Partner! Website:www.herbridge.com

industry focus on the areas of fall blood sugar, fall blood fat, fall blood pressure. Hesperidin can treat hypertension and myocardial infarction, used as pharmaceutical raw materials in pharmaceutical industry. It is one of the proprietary Chinese medicines and the main composition of Chinese patent medicine beniol. In2014, as a result of continuous rain in raw material acquisition period, the farmers can't collect, lead to the production of immature bitter orange cuts severely in the prometaphase, output fell more 50% than last year, according Okaypharm told to Herbridge Media. Most of immature bitter orange extract manufacturers decorate a collection spot around to rush in the harvest the raw material. Thus, the price as a higher record was up 50% to 60% than the same period last year. As for the future market of immature bitter orange extract has not been a clear conclusion. For example, 95% of the specification of hesperidin market charts reference data in 2014 are as follows:

Units:¥/ kg

Herbridge Media will be further observed and reported for market trends of immature bitter orange extract in the future.

5000 tons wolfberry signed in Ningxia

In the July 19, Chinese wolfberry purchasers who come from the national top 10 Chinese medicinal materials circulation markets, large pharmaceutical companies, etc, signed sales agreement of 5000 tons Chinese wolfberry.

Push Corporation and Innovation,Build natural health supply chains! Contact:Gloria Zhang Tel:18182608257 (Xi’an)13521674640(Beijing) E-Mail:[email protected][email protected]

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May 25 of this year,Ningxia Zhongqi Group told Herbridge media, it has been received Chinese wolfberry traders more than 200, transaction amount reach above ¥20 million.

Rugulation

Interpretation of CFDA new rules: Personalized

regulation of plant extracts industry is still far away

On July 29, CFDA announced a notice that related to strengthen supervision and management in the production of traditional Chinese medicine extraction. The file specified: proprietary Chinese medicine production enterprise outsourcing Chinese medicine extract raw materials is prohibited. And demanded that traditional Chinese medicine factory should have extraction ability of corresponding to the varieties and scale of production. OEM processing mode has been stopped Introduction of new regulations directly make the raw material OEM processing mode gradually become history in the traditional Chinese medicine factory production for many years. According industry veteran told to Herbridge Media, most of the pharmaceutical companies have not enough capacity to processing Chinese medicinal materials, as well as some specific plant varieties require special processing techniques, those are need to delegate some plant extract factory to complete. And the new rules to some extent also limited the plant extract factory who can provide special technology processing continue to service for pharmaceutical plant. The two "stop without exception” will to interdict plant extracts into the pharmaceutical industry The two "stop without exception”: The CFDA shall stop the examination and approval of traditional Chinese medicine extraction processing, for approved, it will be valid until December 31, 2015. The proprietary Chinese medicine production enterprises whoever does not have Chinese traditional medicine extraction ability shall stop the corresponding varieties of production since the date of January 1, 2016. Some Chinese plant extracts production enterprises are actively applying for CFDA certification of GMP factory in order to improve the control ability of enterprise in the field of raw materials, to gain the qualification of pharmaceutical grade raw materials processing and to establish business cooperation with traditional Chinese medicine factory, according Herbridge Media. And some

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China Natural ingredients Industry Media Partner! Website:www.herbridge.com Push Corporation and Innovation,Build natural health supply chains! Contact:Gloria Zhang Tel:18182608257 (Xi’an)13521674640(Beijing) E-Mail:[email protected][email protected]

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enterprises basically take such cooperation as the only model of business support. The new rule means that, the production enterprises that originally provide the powder or herbal extracts to the traditional Chinese medicine factory have to seek other development. The new health food laws may make reference to the new rules Zhang Jinjing, supervising officer of health food and cosmetics of CFDA told to Herbridge Media, said that: the new health food law is possible to learning from the new regulations of production of traditional Chinese medicines extracts. In addition, it is planned that “the food safety law" of industry widely attention can finish second and third approval in August and October respectively. But due to solicit opinions from the more, the CFDA as far as possible taken enterprise and industry factors into account. Thus, it is expected to make a second approval until October, The new health food laws will also be implemented and published after “the food safety law” new rules come out completely.

Ingredients

ginger price rises, ginger oil show good prspects

Ginger oil is yellow to brownish red oily liquid that extracted and processed by dry root and rhizome of zingiberaceae plants, smell fragrant, spicy taste. Ginger oil contains active substances including zingiberene, ginger alcohols, ginger ketones and ginger phenol. The aroma of ginger oil depends on its volatile oil; characteristic flavor mainly comes from the non-volatile oils - gingerol. Ginger essential oil, ginger oil resin and gingerol are three of the most important ginger oil products. Ginger oil have the effects of line spirit, resuscitation, dredge blood and remove toxins, unique aroma, is widely used in food, pharmaceutical and personal care products. Prices of ginger oil will rise with the rocketing price of ginger Since last July, the price of ginger has been maintained a steady upward trend, wholesale prices from 5 yuan per kilogram rose to more than 10 yuan, part of regions up to 15 yuan/kg, compared with the same period last year rose more than 150%, according to data of price monitoring system from the ministry of agriculture. The expert analysis shows that, the high price of ginger is mainly due to ginger yield plunged so that the market supply is insufficient in 2013. In addition, affected by the "poison ginger" events, a large number of “toxic” gingers is destroyed that more exacerbate ginger market supply shortage. Because of the influence of raw material rise, ginger oil prices also rose in the first half of this year, it is expected that higher prices of ginger oil will continued to the

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China Natural ingredients Industry Media Partner! Website:www.herbridge.com Push Corporation and Innovation,Build natural health supply chains! Contact:Gloria Zhang Tel:18182608257 (Xi’an)13521674640(Beijing) E-Mail:[email protected][email protected]

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second half of this year. The widely application and good prospects of ginger oil Ginger oil as home remedy or compound essential oil has been widely used in the field of personal care products, it has the effect of the dissipate blood clot, promote the blood circulation as well as favor deeply by the market. In recent years, the application of ginger oil in the hair care market is promising. Zingiberene, ginger alcohols, ginger ketones and ginger phenol derive from ginger oil that can normalize the head skin blood circulation, promote skin metabolism, activate hair follicle tissue, strengthen hair root, effectively prevent hair loss, hair, and stimulate new hair growth. In addition, ginger oil mixed in shampoo can drive intermittent headache, for migraine, recurrent headaches has a certain therapeutic effect. In recent years, European and American markets launched a series of ginger oil health care products. And publicly declared its effectiveness is mainly reflected in: stimulate digestion, promote gastrointestinal health; promote cardiovascular health; as anti-inflammatory supplements, relieve pain and swelling caused by inflammation of the joints and muscle pain; and for anti-nausea and relieve motion sickness caused by travel, etc. Besides, the new study also found that ginger extract has the effect of against colitis, reduce chemotherapy nausea; control weight, to speed up the metabolism, lower cholesterol; its functional component include ginger alcohol - 8 and ginger alcohol -6 which has the effect of control blood sugar. Furthermore, ginger oil and ginger extract can be used as a kind of food and beverage flavor and flavoring agent. Thus, the products that contain ginger tea, ginger candy, ginger powder these condiments and essence are popular with consumers in the market at present. Guangzhou Honsea Sunshine Biotech Co., Ltd. is a professional manufacturer in the field of plant extract, and concentrate to the application and product development of supercritical CO2 extraction technology in the field of plant extract. Its ginger oil selected small turmeric of high quality as the raw material (small turmeric succulent rich, pungency, its gingerol content far more than the meat ginger), processed through supercritical CO2 extract technology. Compared with the traditional method, supercritical CO2 extraction of ginger oil is more pure, and there are no pesticides, polycyclic aromatic hydrocarbons and other residues. Its supply three kinds of specifications of ginger oil: the ginger essential oil that total gingerol was 10% or less, the ginger oleoresin that total gingerol was 20% and 35%, according to Guangzhou Honsea Sunshine Biotech Co., Ltd. disclosed to the herbridge media. Among them, the ginger oleoresin which total gingerol was 20% contains a certain amount of ginger essential oil, because of both ginger essential oil rich aroma, and the characteristics of the high content of gingerol, products are very popular with the market. Influenced by ginger prices, the market price of ginger oil rose 10%. Its future market

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China Natural ingredients Industry Media Partner! Website:www.herbridge.com Push Corporation and Innovation,Build natural health supply chains! Contact:Gloria Zhang Tel:18182608257 (Xi’an)13521674640(Beijing) E-Mail:[email protected][email protected]

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trend depends on the impact of the price of ginger.

Industry

China Herbal ingredients industry expect new

revolution

In the recent decades, it is inseparable that the progress of the plant extracts and natural ingredients industry of China, and the related research results and market demands of current international market. Recently, there is increasing that people pursuit to natural ingredients, whatever in terms of human dietary supplements, herbal medicine products, or supplements in the field of animals and animal medicine. At the same time, the competition of industry also make fiercer. More natural, organic, non-GMO the source of raw material ingredients has become a new focus in this industry. Some international giant launched products which match with the company's nutrition solution or will lead a new competition pattern of natural ingredients. The resources of herbal medicine products transfer abroad Our country has always been an agricultural country, also is the plant extracts industry raw materials supply of power. Natural ingredients have been affected by the international market, and most of the natural ingredients suppliers in China also have been hard for among the international excellent suppliers. A lot of natural ingredients international giant set up R&D and Purchasing Department in China, and began to grab the source of medicinal materials, according to the herbridge media report. Pay attention to the control of the whole industry chain which include selection, seedling and harvest, and build a safer sustainable development strategy. Thereby, control the source for the extraction of natural ingredients more directly, including pesticides and heavy metals, such as pesticide residues. This trend has been reflected in the many large international leading enterprises that include DSM, Indena, Kemin, and will drive the whole industry trend of the source control of medicinal materials. Rosemary and marigold which used to extract the FIC exhibition of rosemary extract and lutein all have its own cultivation base used by, but is not establish cooperation bases in China, according to Kemin disclosed to the herbridge media on this exhibition. The reason is that China's land is fragmented, and the cooperation with several farmers unable to control pesticide residues and

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China Natural ingredients Industry Media Partner! Website:www.herbridge.com Push Corporation and Innovation,Build natural health supply chains! Contact:Gloria Zhang Tel:18182608257 (Xi’an)13521674640(Beijing) E-Mail:[email protected][email protected]

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pesticides well, to make the United States, India and other countries for cultivation of cooperation. Land farmer cooperation in the United States, for example, has been through sustainable plant certification audit of a third party audit institutions SCS scientific certification system. It may improve market competitiveness and influence for the company to provide rosemary extract of sustainable, pure natural high quality to the market. In terms of the domestic market, the company production plant extracts in the use of raw materials in our country has carried out planting base in a number of provinces and regions, unified seed, fertilizer, spray insecticide, harvesting, processing, transport "six unified" management strategy, grab the source of medicinal materials, control the supply sources of natural pigment products in the field of domestic and foreign food, health care products, dietary supplements, according to Henan Zhongda Biological Engineering Co., Ltd. present to the herbridge media. In addition to the company, our country also has some companies began to establish management and control their own planting base, it also confirmed that the part of the enterprises in our country has a certain competitive advantage in the market, while maintaining this advantage, market sensitivity is synchronized with the international market, and to build their own advantage. On the basis of the current enterprise layout, the cultivated and wild medicinal materials industry of China will face a new revolution in the future. Product nutrition solution advantages highlighted Lycored as the global leading supplier of carotenoids technology and the development of natural ingredients formula, shows the original quality nutrition strengthening solution; DSM has also been launched an effective health solutions in the food additives and ingredients of China 2014 (FIC2014); Kemin draw on their clinical research strength to aim at natural antioxidant, as well as provide extend the shelf life of the plan that match with the company's flagship product for related industries; And Wildflavors biological Co., Ltd. already started for beverages terminal to launch related nutrient solution. ... The nutritional health solution that drives by the international giant will lead to the development "style” of the latest form of plant extracts industry. Social responsibility to promote healthy development of the industry Plant extracts is ultimately reflected in food and health products, medicine field. Driven by interest, the food industry, health care products industry is mixed. In terms of synthesis of pigment, there has been related current international market research confirmed that the synthetic pigments will cause ADHD, so natural pigment market looks like good prospects. But in China, the country has not yet issued a mandatory policy to limit the use of synthetic pigment; application of natural pigment in food, candy, health care products field has not yet reached a peak. This, of course,

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China Natural ingredients Industry Media Partner! Website:www.herbridge.com Push Corporation and Innovation,Build natural health supply chains! Contact:Gloria Zhang Tel:18182608257 (Xi’an)13521674640(Beijing) E-Mail:[email protected][email protected]

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needs the national policy and enterprise social responsibility that promote the development of health products in the fields of healthy food, health care products. A part of plant extracts enterprise is on the basis of the demand of terminal companies to provide products. But the adulteration of plant extracts industry also received attention of the world. In recent years, the United States, the European Union and other countries began to stricter controls the natural ingredients that imported from China. On the one hand, the move will train production of high-end products; on the other hand also prompted some companies constantly improve their technology and product ideas. This industry is in the stage of rapid development, competition and opportunities coexist, we believe that natural sources ingredients market will attract more terminal enterprises and as a major competitive factor. Natural ingredients supplier well in terms of social responsibility and sustainable development after enter the Chinese market. We called for that the suppliers of plant extracts can enhance the social sense of responsibility, start from themselves, for the society with high quality products, lay the foundation for establish of the local market of our country natural ingredients, according to the herbridge media report.

Tribulus terrestris extract market keep stable

adequate supply:tribulus terrestris extract The tribulus terrestris widely distributed in Inner Mongolia, the north of Shaanxi, the Central Shaanxi Plain and the loess plateau of China. Its harvest time is the June to October annually. Tribulus terrestris saponins as the main ingredients have lower blood pressure, blood fat, anti-atherosclerosis sclerosis, and strong anti-aging effect. Which contains peroxide decomposing enzyme, have a significant anti-aging effects as well as improve the body immunity. The ingredients can be used to non-hormonal nutritional supplements, because this herb has not contained three major hormones (estrogen, progesterone and testosterone) in any one. That will naturally enhance testosterone, reinforce the strength, improve the overall competitive state, and non-toxic side effects. The new production quantity of tribulus terrestris is sufficient, and its market prices have been stable in 2013. Annual productions reach about 2,000 tons in the major production areas of nationwide. It is expected that the market price of tribulus terrestris change is unlikely before the new production in 2014. market stability for the year Tribulus terrestris extract belongs to the subclass variety of plant extracts, the current domestic market production supply enterprises more concentrated in Shaanxi and Gansu, According to the

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China Natural ingredients Industry Media Partner! Website:www.herbridge.com Push Corporation and Innovation,Build natural health supply chains! Contact:Gloria Zhang Tel:18182608257 (Xi’an)13521674640(Beijing) E-Mail:[email protected][email protected]

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senior official of Gansu Xinhuikang Bio-tech Co.,Lt. disclosed to the herbridge media. Due to limited market demand, production enterprises only a few. Currently, Tribulus terrestris has been widely applied to food, health care products, cosmetics, medicine, chemical industry fields, and general specifications ranging from 20% to 90%. The demand of tribulus terrestris extract on the current market is mainly concentrated in Europe and America, Japan and other countries. Its domestic market applications in the field of medicine, health care products have also increased. It is good prospects that the tribulus terrestris extract used as the materials of energy supplements currently. Since its profit margins is small as well as market demand has been stable, it is expected that the market price of tribulus terrestris change is unlikely before the new production in the first half of 2014.

Astaxanthin price goes up

In China market,Astaxanthin are from two producing way——natural sources extract from Haematococcus pluvialis and producing by fermentation. According Herbridge media,Since the first quarter of 2014, astaxanthin prices climbing in China market. This has grown more than 10% in the domestic market, and increasing more than 20% in the foreign market. In general, the market situation of astaxanthin is optimistic. Currently, the major specifications of Astaxanthin is mainly to 1%, 1.5%, 2%, 2.5%, 3%, 5%, 8%, 10% in the market, that prices ranging respectively from $200 to $1500.

Salvia miltiorrhiza extract keep stable

The common specifications include 10%, 20%, 40% tanshinone type IIA, 7%,10 %, 20 % Salvianolic acid B and 5%, 10% daiclzein, according herbridge. Which Xi’an Honson Bio-Tech Co., Ltd. has a related patent (it was prepared daiclzein by spray counter-current extraction method of process, application number: 201210086309.8 ;). Now, that main supply the Chinese market, the international market in Japan, South Korea, Taiwan, Singapore, Malaysia and other countries for the demand, Honson told herbridge media. The United States pharmacopoeia included the salvia miltiorrhiza in 2010, which promote the progress of salvia miltiorrhiza products to the U.S. market. The international markets are influenced by Chinese traditional culture largely, so the uses of salvia miltiorrhiza are relatively mature. There has MVR, reverse osmosis membrane technology, quantum ring water treatment technology, threaded tube heat exchanger, etc. in salvia miltiorrhiza extract production technology, which can

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significantly reduce the heat to the destruction of the active ingredients, make products to improve the recovery rate of over 25%. As people constantly attach importance to environment, the ingredients of healthy plant extracts that extract from some equipments of energy saving is the trend of the future and the embodiment of the competitiveness. Salvia miltiorrhiza has good curative effect in the aspect of prevention and treatment of cardiovascular disease. In accordance with the seasonal weather conditions, the high-incidence season of cardiovascular disease is winter and spring, so it's the salvia miltiorrhiza extract sales season yet. The off season those include autumn and summer, in which factories mainly in equipment testing and small batch production. Under the influence of national policy and the medicine price, salvia miltiorrhiza markets are basically flat in the first half year, compared with previous years; it is expected to that have a big growth in demand after September in 2014.

Herbridge survey: Silymarin market has increased

steadily

Since the second half of 2012, silymarin market as a whole is relatively stable, according Herbridge Media. But as the inventory consumption step by step, starting from the second half of 2014, prices are likely to gradually enter the slowly rising channel. In the price of Silybum marianum is expected in the near future still is given priority to with stability, and will be fluctuated slightly. At present, Appchem told Herbridge Media, silymarin demand in the international market is about 1000 tons, which domestic demand accounts for some 20% of the total demand; the supply of Silybum marianum in the international market to about 70% of total demand, because China is the leading exporter of international Silybum marianum. Other major export countries are the United States, Germany, Britain, Japan, etc. Mr. Hu, President of Appchem said that the supply of Silybum marianum mainly set up a file in the Panjin area before 2011, because of the influence of the raw material area. In recent years, with the diversified development of the market demand, especially the rapidly increasing demand for high-end products with special specifications, cause as domestic plant extracts technology advantages of the main hub of xi 'an more prominence, makes xi 'an region high-end Silybum marianum extract supply important areas. The supply of raw Silybum marianum largely determines silymarin market trend. According to incomplete statistics, China cultivated area of Silybum marianum is about 0.2~0.25 million of acres in 2014, the annual output of about 15000 tons of milk thistle seeds. If not a major natural

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China Natural ingredients Industry Media Partner! Website:www.herbridge.com Push Corporation and Innovation,Build natural health supply chains! Contact:Gloria Zhang Tel:18182608257 (Xi’an)13521674640(Beijing) E-Mail:[email protected][email protected]

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disaster, production basic meet the market demand, market supply will maintain the basic balance as a whole in the future. Late in the first half of 2015, supply may be tight; prices are likely to have certain rises.

2014CPHI&FIA interview record by Herbridge Media

June,CPHI-SHANGHAI, Herbridge Media interviewed CCCMHPIE organization、China Herbal Ingredients Association and other main manufacturers Liu Zhanglin, vice chairman of CCCMHPIE ORG told to the Herbridge Media, this exhibition will be held in Shanghai CPHI with other six solo exhibition at the same time, the CPHI is the highest level of international exhibitions, with large-scale and high-level, its exhibiting companies has more than 3000, visitors reach 50000, according to preliminary estimates. CCCMHPIE organization to make a lot of practical efforts in promoting national policy and enterprise environment development for promote the industry development; actively promote the development of Chinese pharmaceutical industry and plant extracts. China CCCMHPIE ORG Herbal Ingredients Association will further do more in order to promote China plant extracts internationalization development and the international brand. Plant extracts industry is high degree of industrial chain links as a special industry. There are many aspects of practitioners in the plant resources related to agriculture, rural areas and farmers problems, high value-added extract technology and provided to intake for people's health and nutrition products, and unique competitiveness in the international market, promoting China's economic development. David Zhang, director of China CCCMHPIE ORG Herbal Ingredients Association, for the exhibition points out that Chinese plant extracts industry faces the following issues: 1. Chinese plant extracts industry remains some issues such as products similar, product serial strong repeatability. It's not good for the manufacturers and ingredients industry. 2. The International visitors are less than previous years. Now, more and more International company with offices in China, or domestic proxy agent, international company will entrust domestic offices or agents to come to understand such basic exhibition basically. This market performance of China as the center is good for the industry. 3. Chinese plant extracts industry products lack of innovation, enterprises participated product updates few in the annual, international buyers are familiar with Chinese products increasingly, and expectation value is reduced greatly for multinational exhibition new harvest. This is the Chinese plant extracts industry need to be considered that how to attract more attentions. Yu Zhibin, secretary general of China CCCMHPIE ORG Herbal Ingredients Association told to the Herbridge Media, CCCMHPIE ORG completed 7 plant extracts of chamber of commerce

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standard last year, the work gets the attention of the United States pharmacopoeia committee (USP), and USP will pick three varieties to cooperate. China CCCMHPIE ORG Herbal Ingredients Association will start second round of this year plant extracts standards setting, and want to stand on the height of cooperation of the two sides, with USP will jointly promote Chinese plant extracts standards. As plant extracts in China's largest export market in the United States, a move that will vigorously promote our country extract in the United States market access and market recognition. Yu Zhibin also said that CCCMHPIE ORG will also consider promoting industry GEP certification, reasonable, environmental protection, healthy, efficient and perfect production process as the premise of produce good products, complementary with enterprise credit evaluation system. To abandon price competition era of Chinese plant extracts industry, make health industry of quality decision price and reputation in the future. Alan Liao, general manager of Suzhou Purplestone Biotech Co., Ltd. told to the Herbridge Media, this exhibition huge harvest, Purplestone launch sources of black rice pigment. Meanwhile, its factory in Suzhou will also produce natural probiotic ingredients of microbial sources. Alan Liao always advises that businesses to put forth effort in-depth development of their products, maximizes the value of plant extracts products. However, there always have some problems in the aspect of global food safety such as product of pesticide residues, heavy metal. Those are influence export industry of Chinese plant extracts each year, so company should be made more refined product from raw material, machining process, the production line into the sales to establish traceability links. Richard Li, sale director of Skyherb told to the Herbridge Media, CPHI still be thought of as the most important plant extracts trade show in China, over the years enterprises in the factory and the product level are promoted, and the CPHI has become an important platform of enterprises and peer communication and customer reception. Skyherb is a technical enterprise, is committed to upgrading technology products, the company's green coffee bean extract and grape seed extracts, apple polyphenols in terms of international recognition is very high. While actively involved in plant extracts industry standard drafting work in China, Skyherb is also the herbal medicine association member unit. It introduced new ginseng extract, green tea extract and cranberry extract this year in order to adapt to market development. This a few product itself on the world market has great coverage, but based on the enterprise between the good and bad are intermingled, so it also has the very big promotion space in this kind of product technology and services, Skyherb will continue to strive for bulk products among the ranks of suppliers. There is a big gap between the market of Zhejiang province and the international, Skyherb as plant extracts industry young enterprise itself has a lot to standardize space, the future of it will be based on technologies to promote the core competitiveness, positioning raw material manufacturers to provide more technologies and services for the terminal customers. At the same time, combining

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with greatly health market of China, a lot of food enterprises have begun to focus on the plant ingredients, enterprise will seize the opportunity to develop the domestic market in the future. Liu Zhimou, general manager of Hunan Nuoze Bio told to the Herbridge Media, Hunan Nuoze Bio formerly known as Jilin Tonghua Nuoze biological technology Co., Ltd., relying on the northeast of China plant resources, combining with the company of healthful concept of "professional quality cast, science and technology to create value" to developed schisandra fruit extract with independent intellectual property rights, water-soluble extracts from fructus schisandrae can improve sleep, protect the heart. Fat-soluble extracts from fructus schisandrae (active ingredient of lignin) can protect liver. Product specification also can be supply from 1% to 98%. On the exhibition, Hunan Nuoze Bio launched lead effect of poria cocos extract, its Poria cocos extract signature ingredient is poria cocos, compared to most of market proportion extracts efficacy composition is not quantitative. The demands of poria cocos extract are widely used in the fields of anti-tumor or anti-aging food supplements, health care products and cosmetics. The expelling lead of efficacy of poria cocos extract will make big market opportunities in the future. Zhang Baotang, general manager of Nutra-Max told to the Herbridge Media, plant extracts enterprises in China should be further developed more additional value of their own products, because Chinese plant extracts industry has an irreplaceable advantage in the global market. Plant extracts should reflect its value as natural resources to support human health. It is recommended that companies should maximize the value of the product itself, to put an end to cheap sell as much as possible. Dr. Xu Yingjian, commercial director in the asia-pacific region of Phosphonics told to the Herbridge Media, Phosphonics has a wide range of applications in synthesis of pharmaceutical industry, chemical industry and petrochemical industry. Its chairman of the investment attaches great importance to the Chinese market, the animal extracts and plant extracts industry as a development priority in the next 2-3 years, because as China and the global importance of food safety, plant extracts manufacturer's terminal customer (downstream buyers) of requirements more strictly for heavy metals standards than national standards prescribed by the laws and regulations, such as laws and regulations standard of heavy metals residues for ginseng extract is not higher than 10 PPM, but customers will ask enterprises to controlled it at 0.5 PPM or less. That needs Phosphonics help enterprises to realize. Phosphonics adsorbent of the ability of catch heavy metals is high; its special functional groups hang together with silicon through covalent bond forms, and it can be dissolved in water and organic solvents. While plant extracts industry more used water extraction or alcohol extraction in the process of production, can be realize the efficient removal of heavy metals on the production process for the enterprise. Phosphonics would like to provide

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reliable technical support for producing low heavy metal residues of enterprises of Chinese plant extract. More wonderful video interview details on www.herbridge.com please pay attention to herbridge video columns recently updated.

Nutrition Market & Trends

2014 China's top ten beverage enterprises

1. Coconut palm license: Built in 1956, one of China's largest canned fruit juice beverage

production enterprises, palm Group Ltd.

2. Minute Maid Orange: The Coca-Cola Company's brands that specialized in the development

and production of international beverage companies, Coca-Cola Beverage Co., Ltd.

3. Coca-Cola: invented in 1886, ranked first in global sales of carbonated drinks, Coca-Cola

USA

4. Unified Orange more: Unified Group’s sub-brand, specialized diet product research and

development, production and marketing, the top ten beverage brands, Uni-President China

Holdings Ltd.

5. Pepsi: founded in 1890 to invest in the United States,, large multinational companies, PepsiCo

(China) Co., Ltd.

6. Master ice tea: Founded in 1958 in Taiwan,, Tingyi Holdings Ltd.

7. Huiyuan Juice: Chinese famous brand, the key state enterprises, Huiyuan Beverage and Food

Group Co., Ltd.

8. Wahaha: Founded in 1987, one of China's largest food and beverage manufacturer, Hangzhou

Wahaha Group Co., Ltd.

9. Silver Heron: Chinese famous brand, brand-name products in Fujian Province, China's top

500 private enterprises in Xiamen Yinlu Group

10. Red Bull: from Thailand, functional beverage research and production company, Red Bull

Vitamin Drink Co., Ltd.

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2014 the world's top ten enterprises

1-Nestlé

2-Cargill

3-Unilever

4-PepsiCo

5-Kraft Foods

6-InBev

7-Mars

8-Coca-Cola

9-Tyson

10-SABMiller

2014 China's top ten chocolate brands

1. Dove, Mars Foods (China) Co., Ltd.

2. Le Conte chocolate, COFCO Le Conte Food (Shenzhen) Co., Ltd.

3. Meiji Chocolate, Meiji Seika (Shanghai) Co., Ltd.

4. Glico chocolate, Shanghai Ezaki Glico Foods Co., Ltd.

5. Cadbury, Cadbury Schweppes Co., Ltd.

6. SWISS THINS, Lindt & Sprüngli company

7. GUYLIAN, Classic Belgian chocolate brand

8. FERRERO ROCHER, Italian Ferrero Rocher Group

9. HERSHEY'S, American Hershey Company

10. M & M's Chocolate, Mars and Hershey together to create

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Conference news

China Natural Ingredients Conference 2014 will be held

on 30th-31st,October,In Hangzhou City

China Natural Ingredients Conference 2014

Time: 30th-31st,October Hangzhou Vaton Yunqi Resort Hotel

Organizers:

CCCMHPIE ORG Herbridge Media

Co-Organizers:

Sponsors:

Ads-Sponsors:

Your LOGO

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Supporters:

Theme:Branding、Updating、Whole chains coorperating Agenda

Topics Morning 30th,October (Overview、Tech and Regulations)

9:00AM-12:10AM

Topic: China herbal ingredients establish Standardization 2rd round

Speaker: Liu Zhanglin, CCCMHPIE ORG, Vice Chairman

Topic: Reference American standardized plant extract construction

Speaker: Dr.Hu Jiangbin,USP,Chairman(China)

Topic: Minimising heavy metal impurities; maximising global returns.

Speaker: Andy Xu,PhosphonicS UK,Asia & Pacific Business Director

Topic:《Food Safty Law》second audit round finished,New regulation interpretation

Speaker: zhang jinjing,CFDA ,Health food& cosmetics supervision department inspector

12:10-14:00Lunch Time

Afternoon 30th,October(Industry Opinions and Corperations)

14:00PM-18:00PM

Topic:New product development and market explore --Maca extract Speaker:Zheng Qunyi Herbalife Lei Shuo Natural Products Co.,Ltd ,CEO

Topic: US dietary supplements industry Present situation and Chinese natural ingredients

industry‘s moral, integrity and mission

Speaker: David Zhang Shanghai Freemen LifeScience Co.,Ltd General Manager

Topic: Herbal resource new role:Natural Prebiotics

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Speaker: David Zhang, China CCCMHPIE ORG Herbal Ingredients Association, Director

Topic: Built a Successful Supplier & Customer Relationship

Speaker: Wenwen Ma, Ph.D, Unigen Inc,VP of Operations

Topic: Health care (health food) research develop and trends in DaJiankang

Speaker: Yu Hongjian, Zhejiang Jianfeng Health Tech.Co.,Ltd., General Manager

First day conference ending by 18:00 pm

18:00pm-21:00pm Dinner and previous speaker Awards

Morning,31st,October(Innovation and Formulation Design)

8:30AM-12:10AM

Topic:To be submitted

Speaker: Pro.Zhao Yuqing,Shenyang Pharmacutical University,TCM college Dean

Topic:Slendesta—the latest Weight control ingredients from nature

Speaker: Robin Ruan, Kemin (China )Human Nutrition and Health,Business Director

Topic:where is the way out?-herbal ingredients to healthy terminal

Speaker: Gerard.VinyesPares ,Nestle(China)Research Center(inviting)

Topic: Several activie herbal ingredients use in nutrition formula

Speaker:Linda Zhao, Abbott(China)R&D Center,(inviting)

Topic:China natural health industry develop situation and trends

Speaker: By-Health R&D Center(inviting)

Topic:Natural Ingredients’Quality control in the downstream products

Speaker: Infinitus Q.C department(inviting)

Topic:Relationship anylize between human health and intestinal microflora

Speaker::Dr.Qinnan Zhejiang University Genomics lab platform group leader Chinese

Preventive Medicine Association digestion and nutrition branch leader

Topic: marine resources develop and Da Jiankang

Speaker: Cao Rongjun blue economic zone of Marine Biological Industry Alliance

General secretary;Qingdao Belt Biological Technology Co., Ltd,President

12:10-14:00PM , Lunch Time

Afternoon,31st,October(Hot Japan Natural Ingredients special subjects)

14:00PM-17:30PM

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Japan health industry circulation News Agency promote 2014CNIC to Japan Natural

Ingredients Industry and health products Industry, Will bring active Japanese natural

ingredients enterprises and the characteristics of health products enterprises participate

and share new ideas and information.

Second day conference ending by 17:00

Forum I:Natural Colors Innovation and Application in China(Afternoon

30th,October) 14:00PM-18:00PM Conference Hall—— RuiQi Hall

Host by Alan Liao(Shanghai PurpleStone Biotech. Co., Ltd. General Manager)

Topic: Natural color market opportunities in China and global

Speaker: Chairman,China Natural Color Committee(to be confirmed)

Topic: Global Natural color trends and natural blue color new aspect

Speaker: Chengjianbin,Chr-Hansen A/S,R&D Technical Director

Topic: Natural Color technich innovate and application solutions

Speaker: Alan Liao, Shanghai PurpleStone Biotech. Co., Ltd. General Manager

Topic: Natural Color health value analysis in health food industry

Speaker: Qing Huang,Tomimoto Co.,Ltd,CEO

Forum II、Natural Ingredients Applicated in Personal care products(Morning,31st,October)

8:30AM-12:10AM

Host :Recruiting Topic:Herbal ingredients use in personal care products trends

Speaker: He Jun Foch-Unicare,R&D Director

Topic: high concentration of herb extracts develop direction and opportunities

Speaker: Hu Huoming Kolmar Cosmetics Co., Ltd. Tech Director

Topic: foreign natural personal care products develop in China

Speaker: Zhang Senfu, Nature's Gate US Inc ,President

Topic: New herbal ingredients adding trends in Functional toothpaste

Speaker: Liu Dushu,Liby group,Engineer Conference Scale:more than 350 participants.

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The main participants are Included and not limited to Amway (China)、Herbalife、

Unilever(China) 、COFCO、NBTY INC,AUROPURE LIFESCIENCE ,Uningen,

Ingredion、PERFECT (CHINA) 、Indena S.p.A.、Kao(China) Research & Development

Centre Co.,Ltd、Sirio Pharma Co., Ltd、LycoRed、Chr-Hansen A/S、PhosphonicS UK、

Unigen、TOKIWA PHYTOCHEMICAL CO.,LTD、MKCORP、Draco Natural Prodcts Ltd、

DSM China、North China Pharmaceutical Group、Jahwa group、Infinitus(China)

Beijing Zhifengtang、Beijing Tongrentang group、China Meheco Group and almost

all China herbal ingredients Manufacturers etc;

Registration:RMB:¥3000/person.

Registration telephone:86-29-88814264, 86-10-88814264,

86-18182628257

Mail: [email protected] ,Gloria Zhang

Previous CNIC Photos:

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