Chondroma cutis

8/2/2019 Chondroma cutis

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M 45, neck, asymptomatic dermal nodule

Deba P Sarma, MD

Omaha

M 45, neck nodule

Diagnosis:

Chondroma cutis

Comment:

Well-circumscribed dermal tumor nodule,no extension into the subcutis. Composed of mature hyaline

cartilage with normal chondrocytes within a homogeneous basophilic stroma.

Chondrocytes show single small nuclei without any significant atypia.

No necrosis or mitotic figures.

Secondary ossification or calcification not present.

Periphery of the tumor is free of any giant cell reaction, granulation tissue or any evidence of

traumatic tissue reaction.

Lesion appears to be a true chondroma in the dermis.

REF:

Sarma DP, Chen M, Wang B (2007). Chondroma cutis. The Internet J Dermatol 6(1).

Indexed by Google Scholar.
http://www.dermpedia.org/files/images/chondroma_cutis.article_g02.fs.jpghttp://www.dermpedia.org/files/images/Picture1_25.jpghttp://www.dermpedia.org/files/images/chondroma_cutis.article_g02.fs.jpghttp://www.dermpedia.org/files/images/Picture1_25.jpg


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Chondroma Cutis

Deba P. Sarma M.D.

Professor of Pathology

Creighton University Medical School

Omaha Nebraska USA

Mingkui Chen M.D., Ph.D.

Resident of Pathology


Omaha Nebraska USA

Bo Wang M.D.

Assistant Professor of Pathology


Omaha Nebraska USA

Citation: D. P. Sarma, M. Chen & B. Wang : Chondroma Cutis . The Internet Journal of Dermatology.

2007 Volume 6 Number 1

Keywords: Chondroma | cartilaginous lesion of the skin | cutaneous chondroma | chondroma cutis

Case Report

This is a photomicrograph (Figure 1) of a biopsied asymptomatic skin nodule from the anterior neck of

a 45-year-old man. There was no history of trauma or previous surgical procedure in this location. The

epidermis is somewhat raised with hyperkeratosis and acanthosis. The upper dermis shows fibrosis. A

well-circumscribed dermal tumor nodule shows no extension into the subcutis. The tumor is composed

of mature hyaline cartilage with normal chondrocytes within a homogeneous basophilic stroma. The

chondrocytes show mostly single small nuclei without any significant atypia (Figure 2). There is no

necrosis or mitotic figures. Secondary ossification or calcification is not present. The periphery of the

tumor is free of any giant cell reaction, granulation tissue or any evidence of traumatic tissue reaction.

The lesion appears to be a true chondroma in the dermis.


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Figure 1: Skin biopsy, anterior neck, low magnification.

Figure 2: High magnification.

Comment

Chrondroma cutis is a rarely seen in the dermatology or pathology practice.

One may occasionally see an extraskeletal chondroma occurring in the soft tissue near the small joints

of the hands and feet of adults 1. These lesions are thought to be originating from the synovial tissue

because of their location near the tendon or tendon sheath 2. Such lesions have been rarely found in

other sites, such as, the head, neck, trunk, oral cavity, larynx, and pharynx 3. Benign mixed tumor of

the skin, also called chondroid syringoma, may present as a cartilaginous dermal or subcutaneous

nodule. However, the tumor is composed of epithelial cords within a chondroid stroma. Rarely, a

cartilaginous rest called wattle, probably of branchial cleft origin may be found in the lateral neck of

infants. Histologically, the subcutaneous mass is composed of skin with adnexal structures with a

central core composed of cartilage and adipose tissue 4. In our patient, the benign cartilaginous tumor

appears to be a true chondroma cutis. There is no suggestion that the dermal cartilaginous nodule is

related to a metaplastic process secondary to trauma or previous surgery. It is located in the dermis

of the anterior neck without any connection to the larynx or any other adjacent structure. There is no

evidence of thyroglossal or branchial cleft cyst.

Correspondence

Bo Wang, M.D.

Department of Pathology


Omaha, Nebraska 68131

References

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Chondroma cutis