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المملكة العربية السعوديةهلية
أ كلية الفارابي ال
Kingdom of Saudi Arabia
Alfarabi Private College
Title
Respiratory system
Course specifications
المملكة العربية السعوديةهلية
أ كلية الفارابي ال
Kingdom of Saudi Arabia
Alfarabi Private College
Code: RS351
Title: RESPIRATORY SYSTEM
Year: Three
Level: Five
No of weeks: Six
Type of educational unit: Longitudinal course Integrated block
No of credit hours: 4 (2+1+1)
Pre-requisites for the course: Principle of diseases II
Course principle coordinator: Dr. Mohamed Samer Rastam
Course support coordinator: Dr. Safaa Masoud Hanafy
Members of the Coordinating Committee:
1- Dr. Mohmed Samer Rastam
2-Dr. Ahmed Abdel Rahman Morsy
3- Dr. Mohamed Bahr
4- Dr. Safaa Masoud Hanafy
Description
The block is designed to provide in depth knowledge of normal and disease processes that involve the
lung and respiratory system. At completion of the course, students should understand the normal structure
and function of the respiratory system and know how these can be affected by disease. The course takes a
pathophysiologic approach, integrating anatomy and histology principles, physiology of respiration,
pathology of respiratory and lung disorders, relevant biochemistry, microbiology and pharmacologic
information.
The block will also introduce students to the various upper respiratory and pulmonary disorders, many of
which are common in the general population. Because many of these conditions are chronic and can
impact other tissues and organs, it is important that students understand their pathophysiology and
treatment. The module will introduce them to upper respiratory and pulmonary disorders, discuss
shortness of breath and other clinical features in the context of specific disorders, incorporate pertinent
laboratory tests and ancillary studies into clinical problem solving, and provide a solid background and
understanding of pharmacologic agents and non-pharmacologic interventions used to treat upper
respiratory and pulmonary disorders.
المملكة العربية السعوديةهلية
أ كلية الفارابي ال
Kingdom of Saudi Arabia
Alfarabi Private College
Objectives
NQF Learning Domains
And Course Learning Outcomes
Course Teaching
Strategies
Course Assessment
Methods
Knowledge
Explain the normal structure and function of the
respiratory system. (SaudiMEDS-1.1)
Lectures &
tutorials
Written
examinations
Explain the biochemical, molecular and cellular
mechanisms that are essential for maintaining body
homeostasis. (SaudiMEDS-1.3)
Lectures &
tutorials
Written
examinations
Explain the pathogenesis of various diseases such as
genetic, developmental, ischaemic, metabolic, toxic,
infectious, autoimmune, neoplastic, degenerative, and
traumatic factors, and the ways in which they affect the
respiratory system. (SaudiMEDS-1.4)
Lectures &
tutorials
Written
examinations
Explain the principles of essential clinical investigations
of patients with cardiovascular problems (SaudiMEDS-
1.5)
Lectures &
tutorials
Written
examinations
Demonstrate a basic knowledge of the pharmacological
principles of drugs relevant to clinical practice.
(SaudiMEDS-1.6)
Lectures &
tutorials
Written
examinations
Explain the general principles of cancer diagnosis
Describe and explain the basic aspects of common
clinical presentations relevant to the respiratory system
(SaudiMEDS-1.8)
Lectures &
tutorials
Written
examinations
Explain the facts and concepts relevant to common
clinical conditions including their epidemiology,
aetiology, pathophysiology, symptoms and signs,
complications, investigations, management and
prognosis. (SaudiMEDS-1.9)
Lectures &
tutorials
Written
examinations
Describe the principles of epidemiology of common
diseases within a defined population and a systematic
approach to screening to reduce the incidence and
prevalence of those diseases. (SaudiMEDS-9.1)
Lectures &
tutorials
Written
examinations
List causes and types of congestion and describe its
morphologic changes
Lectures &
tutorials
Written
examinations
Describe the pathophysiological basis and outcome of
embolism and thrombosis
Lectures &
tutorials
Written
examinations
Describe parasites classification, structure, life cycle,
pathogenesis, and host-parasite interaction
Lectures &
tutorials
Written
examinations
Describe the anatomy of the upper and lower respiratory
tracts.
Lectures &
tutorials
Written
examinations
Recognize and describe the functions of the respiratory
system and the mechanisms by which they are done (Gas
transport and exchange).
Lectures &
tutorials
Written
examinations
Describe the control of respiration and related problems. Lectures & Written
المملكة العربية السعوديةهلية
أ كلية الفارابي ال
Kingdom of Saudi Arabia
Alfarabi Private College
tutorials examinations
Describe the pathogenesis of the respiratory system
disorders.
Lectures &
tutorials
Written
examinations
State different methods used to investigate, manage and
control the respiratory diseases.
Lectures &
tutorials
Written
examinations
Recognize the effects of Sympathomimetics and
autacoids in addition to their related receptors on the
bronchial tree )
Lectures &
tutorials
Written
examinations
Describe different drug therapies used for treatment of
bronchial asthma& chronic obstructive lung diseases, as
well as chest infections.
Lectures &
tutorials
Written
examinations
Cognitive Skills
Select and apply the most appropriate and cost effective
diagnostic procedures. (SaudiMEDS-6.2)
Clinical &
Practical sessions
Spotter examination
Demonstrate the importance of psychosocial, spiritual,
religious, and cultural factors in patient management.
(SaudiMEDS-6.1)
Clinical &
Practical sessions
Spotter examination
Demonstrate reasoning skills to formulate and prioritize a
differential diagnosis. (SaudiMEDS-4.1
Clinical &
Practical sessions
Spotter examination
Critically analyze clinical data obtained through history,
physical examination, and investigation. (SaudiMEDS-
3.4)
Clinical &
Practical sessions
Spotter examination
Be able to demonstrate the histology of the upper and
lower respiratory tract.
Clinical &
Practical sessions
Spotter examination
Demonstrate the basic hospital infection control measures
for inhaled pathogens.
Clinical &
Practical sessions
Spotter examination
Interpersonal Skills & Responsibility
Manage appropriately patients with acute and chronic
medical conditions. (Saudi MEDS- 6.3)
Enumerate, describe and investigate the common
pathogens affecting the respiratory system.
Demonstrate proper techniques for history taking and
clinical examination of the
respiratory system.
Communication, Information Technology, Numerical
Psychomotor
Obtain an accurate and comprehensive medical history. (Saudi MEDS- 3.1) OSPE
Perform a complete systematic physical examination. (Saudi MEDS- 3.2) OSPE
Content
Topics to be covered in this block:
Lung volume, spirometry and pulmonary function tests
Exchange of gases
Embryology of the respiratory system
المملكة العربية السعوديةهلية
أ كلية الفارابي ال
Kingdom of Saudi Arabia
Alfarabi Private College
Regulation of ventilation
Epidemiology of lung diseases
Pathophysiology of lung diseases
Clinical presentation of obstructive lung disease
Pharmacological agents in bronchial asthma
Clinical presentation of restrictive lung disease
Pharmacological agents in bronchial asthma
Clinical presentation of restrictive lung disease
Microbiology of Tuberculosis
Pharmacological agents in Tuberculosis
Microbiology of Pneumonia
Antibiotics for pneumonia
Radiology in respiratory diseases
Lung tumors
Pleural diseases
Socio, cultural, community and ethical issues related to diseases of the respiratory system.
Mechanics of ventilation
Occupational lung diseases
Newly emerging respiratory pathogens
Pulmonary embolism
Chronic Obstructive Lung Disease
Restrictive Lung Disease
Learning strategy
The block will utilize the student-centeredness, integration and the PBL approaches to maximize
correlation, learning and retention of the learned knowledge, skills and attitudes. Lectures will be of the
interactive type and as few as possible. Certain materials will be studied through practical sessions and
some of the important issue related to seminars will be learned.
Hours Lecture PBL Practical sessions SKILL LAB Other Total
Contact 5x6 4x2 9 7 54
Credit 2 1+1
4
Timetable
Week One Respiratory infection 1
Type of activity Code Title of activity Male T. Female T.
Lecture 1 L1 Anatomy of upper respiratory
system
مسعودصفاء . د تامر دمحم. د
Lecture 2 L2 Lymphoid tissue of respiratory
system
مسعودصفاء . د تامر دمحم. د
Lecture 3 L3 Microorganisms affecting رهام الفوال د دمحم أمين. د
المملكة العربية السعوديةهلية
أ كلية الفارابي ال
Kingdom of Saudi Arabia
Alfarabi Private College
respiratory system إيمان النقيب. د
Lecture 4 L4 T.B microbiology رهام الفوال د دمحم أمين. د
إيمان النقيب. د
Lecture 5 L5 Pathology of upper respiratory
infections
أمال عبد الحافظ. د سامر رستم. د
Practical session 1 PS 1 Anatomy and imaging anatomy of
upper respiratory tract
مسعودصفاء . د تامر دمحم. د
Practical session 2 PS 2 Anatomy and imaging anatomy of
lower respiratory system
مسعودصفاء . د تامر دمحم. د
Practical session 3 PS 3 Histology of upper respiratory tract أحمد مرسي. د أحمد مرسي. د
Practical session 4 PS 4 Histopathology of upper respiratory
tract
أمال عبد الحافظ. د سامر رستم. د
Week Two Respiratory infection 2
Type of activity Code Title of activity Male T. Female T.
Lecture 1 L6 Pathology of T.B أمال عبد الحافظ. د سامر رستم. د
Lecture 2 L7 Drug therapy of T.B دمحم بحر. د سيد دمحم ياسين. د
Lecture 3 L8 Pathology of pneumonia and lung
abscess
أمال عبد الحافظ. د سامر رستم. د
Lecture 4 L9 Treatment of lung infections دمحم بحر. د سيد دمحم ياسين. د
Lecture 5 L10 Functional anatomy of pulmonary
vessels
مسعودصفاء . د تامر دمحم. د
PBL 1 PBL 1 Case (1): brain storming
Skill lab SL1 History taking ( chest case ) الخوليأمل . د دمحم أمين. د
Practical session 1 PS 5 Histology of the lower
respiratory system
أحمد مرسي. د أحمد مرسي. د
Practical session 2 PS 6 Histopathology of lung infections عبد الحافظأمال . د سامر رستم. د
Week Three Lung mechanics
Type of activity Code Title of activity Male T. Female T.
Lecture 1 L11 Pathophysiology of pulmonary
vascular diseases
رهام الفوال د سيد دمحم ياسين. د
Lecture 2 L12 Lung volumes and capacities رهام الفوال د سيد دمحم ياسين. د
Lecture 3 L13 Ventilation رهام الفوال د سيد دمحم ياسين. د
Lecture 4 L14 Lung histology مرسي أحمد. د مرسي أحمد. د Lecture 5 L15 Lung recoil and compliance رهام الفوال د سيد دمحم ياسين. د
PBL 1 PBL 2 Reporting of case 1 PBL2 PBL3 Case (2): brain storming Practical session 1 PS 7 Spirometry رهام الفوال د سيد دمحم ياسين. د
Skill lab SL 2 History taking الخوليأمل . د دمحم أمين. د
Week Four Obstructive pulmonary diseases
Type of activity Code Title of activity Male T. Female T.
المملكة العربية السعوديةهلية
أ كلية الفارابي ال
Kingdom of Saudi Arabia
Alfarabi Private College
Lecture 1 L16 Airway histology مرسي أحمد. د مرسي أحمد. د Lecture 2 L17 Airway resistance and pulmonary
function tests
رهام الفوال د سيد دمحم ياسين. د
Lecture 3 L18 Pathology of bronchial asthma and
bronchiectasis
الحافظ عبد أمال. د سامر رستم. د
Lecture 4 L19 Treatment of bronchial asthma بحر دمحم. د سيد دمحم ياسين. د Lecture 5 L20 Pathology of chronic bronchitis and
emphysema
الحافظ عبد أمال. د سامر رستم. د
PBL 1 PBL 4 Reporting of case 2 PBL 2 PBL 5 Case (3): brain storming Skill lab SL 3 Chest physical examination الخوليأمل . د دمحم أمين. د
Skill lab SL 4 Chest physical examination الخوليأمل . د دمحم أمين. د
Week Five Restrictive pulmonary diseases
Type of activity Code Title of activity Male T. Female T.
Lecture 1 L21 Clinical features of obstructive
pulmonary diseases
الخوليأمل . د دمحم أمين. د
Lecture 2 L22 Treatment of COPD بحر دمحم. د دمحم ياسينسيد . د Lecture 3 L23 Gas exchange and blood gases
transfer
رهام الفوال د سيد دمحم ياسين. د
Lecture 4 L24 Regulation of breathing رهام الفوال د سيد دمحم ياسين. د
Lecture 5 L25 Pathology of interstitial fibrosis and
cystic fibrosis
الحافظ عبد أمال. د سامر رستم .د
PBL 1 PBL 6 Reporting of case 3 PBL 2 PBL 7 Case (4): brain storming Practical session 1 PS 8 Histopathology of chronic
pulmonary diseases
الحافظ عبد أمال. د سامر رستم. د
SKILL LAB SL 5 Simulation of breathing sounds
(normal and abnormal)
الخوليأمل . د دمحم أمين. د
Week Six Respiratory system neoplasm
Type of activity Code Title of activity Male T. Female T.
Lecture 1 L26 Pathology of pneumoconiosis and
RDS
الحافظ عبد أمال. د سامر رستم. د
Lecture 2 L27 Clinical features of restrictive
pulmonary diseases
الخوليأمل . د دمحم أمين. د
Lecture 3 L28 Pathology of vocal cord neoplasm
and its clinical features
الحافظ عبد أمال. د سامر رستم. د
Lecture 4 L29 Pleural neoplasm and pleural
effusion
الحافظ عبد أمال. د سامر رستم. د
Lecture 5 L30 Pathology of lung neoplasm and its
clinical features
الحافظ عبد أمال. د سامر رستم. د
PBL 1 PBL 8 Discussion of case 4 SKILL LAB 1 SL 6 Revision الخوليأمل . د دمحم أمين. د
المملكة العربية السعوديةهلية
أ كلية الفارابي ال
Kingdom of Saudi Arabia
Alfarabi Private College
SKILL LAB 2 SL 7 Revision الخوليأمل . د دمحم أمين. د
Practical session 2 PS 9 Histopathology of the respiratory
system neoplasm
الحافظ عبد أمال. د سامر رستم. د
Assessment strategy
Assessment of students will employ a battery of assessment tools that are fit-for-purpose and reliable.
Knowledge will be assessed through MCQ-type written exam and computer-based spotter exam. These
will be conducted at the middle of the block & at its end. In addition to the mid-block written exam,
continuous assessment will be done through the evaluation of performance in PBL sessions and through
assignments.
Schedule of assessment tasks for students during the course
Assessment task Week Due % of Total Assessment
1 PBL evaluation All weeks 10%
2 Midterm Exam 18-12-2016 20%
3 Spotter exam 8-1-2017 20%
4 OSCE 15-1-2017 10%
5 Final Written Exam 22-1-2017 40%
Recommended reading
Clinically Oriented Anatomy, 6th edition, 2009, Keith Moore.
The Developing Human: Clinically Oriented Embryology. K.L. Moore and T.V.N Persaud, 8th
edition. W.B. Saunders Co.
Textbook of Medical Physiology. Guyton and Hall, 12th edition. Elsevier’s Saunders.
Human Physiology from Cells to Systems. Sherwood, 7th edition. Yolanda Cossio.
Robbins and Cotran; Pathological Basis of Disease. Kumar, Abbas, Fausto and Aster, 8th edition,
Saunders.
Medical Microbiology. Patrick R. Murray, Ken S. Rosenthal, Michael A. Pfaller, 6th edition.
Mosby-Elsevier.
Basic & Clinical Pharmacology. B. G. Katzung, 12th edition. McGrow-Hill.
Bates' Guide to Physical Examination & History Taking. Bickley L.S., and P.G. Szilagyi, 10th
edition. Lippincott Williams & Wilkins.
Cecil Essentials of Medicine. Thomas E. Andreoli, C. C. Carpenter, R.C. Griggs, and J. Loscalzo,
8th edition. Saunders
Patrick R. Murray, Ken S. Rosenthal, Michael A. Pfaller, eds. Medical Microbiology. 6th
edn.,
Elsevier-Mosby, 2009.
Cedric Mims, Hazel M Dockrell, Richard V. Georing, eds. Medical Microbiology. 3rd
edn.,
Mosby, 2004.
Ellen Baron, Peterson L, Finegold S, eds. Bailey and Scott's Diagnostic Microbiology. 12th edn.,
Mosby, 2006.
المملكة العربية السعوديةهلية
أ كلية الفارابي ال
Kingdom of Saudi Arabia
Alfarabi Private College
Arthur C. Guyton, John E. Hall, eds. Textbook of Medical Physiology, 11
th Edn., Elsevier
Saunders, 2006.
Vinay Kumar, Abul K. Abbas, Nelson Fausto, eds. Robbins and Cotran Pathologic Basis of
Disease. 7th Edn. Saunders, 2004.
Robert K. Murray , Darryl K. Granner, Peter A. Mayes, Victor W. Rodwell, eds. Harper's
Illustrated Biochemistry. 27th Edn. Elsevier, 2006.
Douglas G, Nicol F, Robertson C, eds. Macleods Clinical Examination, 2005
Jacqueira LC, Carneiro J, Kelly RO, eds. Basic Histology. 11th edn., Lange Reviews, 2007.
Snell RS. Clinical Anatomy for Medical Student, 7th Edn. Lippincott, Williams &Wilkins, 2004.
T.W. Sadler. Langman’s medical Embryology. 12th Ed. Lippincott Williams and Wilkins (2009)
Bertram G Katzung, ed. Basic and Clinical Pharmacology, 10th edn. Lange. 2004.
Lee Goldman and Dennis Ausiello, eds. Cecil Textbook of Medicine. 22nd
Edn. Saunders
Publisher, 2004.
Recommended electronic resources
www.pharmacology2000.com
www.cdc.gov
www.webpath.com
www.imc.meded.com
www.med.unc.edu/embryo_images
www.anatomyatlases.org/atlasofanatomy/index.html