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curriculum vitæ

Cristina Maria Nogueira da Costa Santos

July 2010

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Contents

CONTENTS ....................................................................................................................................................... 3

PERSONAL DATA ............................................................................................................................................ 5

ACADEMIC DEGREES .................................................................................................................................... 5

COMPLEMENTARY FORMATION ................................................................................................................ 6

INTENSIVE COURSES ........................................................................................................................................ 6 INTERNSHIPS .................................................................................................................................................... 6

ACADEMIC POSITIONS .................................................................................................................................. 7

PARTICIPATION IN RESEARCH PROJECTS ................................................................................................ 7

COURSES TAUGHT .......................................................................................................................................... 8

UNDERGRADUATE ........................................................................................................................................... 8 POSTGRADUATE ............................................................................................................................................... 9

MSC COMMITTEES ........................................................................................................................................ 11

MSC ADVISORY .............................................................................................................................................. 12

PUBLICATIONS .............................................................................................................................................. 13

FULL PAPERS IN INTERNATIONAL SCIENTIFIC PERIODICALS WITH REFEREE (INDEXED BY ISI) .................... 13 LETTERS TO THE EDITOR PUBLISHED IN INTERNATIONAL SCIENTIFIC PERIODICALS WITH REFEREE

(INDEXED BY ISI) ................................................................................................................................................. 15 PUBLICATIONS IN SCIENTIFIC PERIODICALS WITH REFEREE (NOT INDEXED BY ISI BUT INDEXED BY

MEDLINE) ............................................................................................................................................................. 15 OTHER PUBLICATIONS ................................................................................................................................... 15 THESIS............................................................................................................................................................ 16 ABSTRACTS ..................................................................................................................................................... 16

ORAL COMMUNICATIONS .......................................................................................................................... 19

POSTERS .......................................................................................................................................................... 21

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Personal Data

Name: Cristina Maria Nogueira da Costa Santos

Date of birth: 03 / 03 / 1972

Nationality: Portuguese

Marital Status: married

Institutional address: Faculdade de Medicina da Universidade do Porto

Serviço de Bioestatística e Informática Médica

Alameda Prof. Hernâni Monteiro

4200-319 Porto

Portugal

Email: csantos.cristina@gmail.com

Homepage: http://users.med.up.pt/csantos

Academic degrees

PhD in Clinical and Health Services Research, Faculty of Medicine, University of Porto

MSc in Statistics and Information Management, ISEGI, New University of Lisbon

BSc in Applied Mathematics, Faculty of Science, University of Porto

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Complementary Formation

Intensive courses

July 2008 - “Using R for Advanced Statistical Analysis"

by Prof. Jaroslaw Harezlak, Indiana University.

Biostatistics and Medical Informatics dep., Faculty of Medicine, University of Porto.

May 2003 - “Survival Analysis"

by Professors David Kleinbaum and Mitch Klein, Emory University.

Hygiene and Epidemiology Dep., Faculty of Medicine, University of Porto.

June 1999 - "Stratification, Matching and Clustering in Health-related Studies"

by Prof Tim Peters, Department of Social Medicine, University of Bristol and

Prof. Denisa Mendonça, Departamento de Estudos e Populações, University of Porto.

Departamento de Estudos e Populações, ICBAS, Universidade do Porto.

Internships

1998-1999 - Internship - Information Management

“Sistemas de informação baseados na web: análise, desenho e implementação”,

Biostatistics and Medical Informatics Dep., Faculty of Medicine, University of Porto.

Scientific adviser: Prof. António Nóbrega de Sousa Câmara, New University of Lisbon

Professional adviser: Prof. Altamiro da Costa Pereira, University of Porto.

1993/1994 - Internship - Erasmus (European Region Action Scheme for the Mobility

of University Students)

Facultad de Matematicas de la Universidad Complutense de Madrid, Spain.

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Academic positions

2010- - Assistant Professor (Professor auxiliar), Faculty of Medicine, University of Porto

2002- 2010- Lecturer (Assistente), Faculty of Medicine, University of Porto

1999-2002 - Invited Lecturer (Assistente convidada), Faculty of Dentistry, University of Porto

1996-1998 - Teaching Assistant (Monitora), Faculty of Dentistry, University of Porto

Participation in research projects

2010- - Project “CSI - Cryptographic Security for Individual Instances”.

Fundação para a Ciência e Tecnologia - FCT (PTDC/EIA- CCO/099951/2008)

2002-2005 - Project "Tacographic, spectral and fractal heart rate analysis during pre and post-natal life.

Applications in medical diagnostic and educational systems".

Fundação para a Ciência e Tecnologia - FCT (POSI/CPS/40153/2001)

1996-1999 - Project "Multicenter validation of the cardiotocogram automated analysis system -

SisPorto".

Junta Nacional de Investigação Científica e Tecnológica - JNICT (2/2.1/SAU/1351/95)

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Courses taught

Undergraduate

2007- - Introduction to Medicine II: Information in Health.

Faculty of Medicine, University of Porto.

2st semester, 1st year of Master Degree of Medicine

(5 ECTS - 50 contact hours).

2007- - Introduction to Medicine I: Theory of Medicine.

Faculty of Medicine, University of Porto.

1st semester, 1st year of Master Degree of Medicine

(5 ECTS - 50 contact hours).

2002-2006 - Introduction to Medicine.

Faculty of Medicine, University of Porto.

Annual, 1st year of Medicine Graduate (100 contact hours).

1996-2002 - Introduction to Medicine.

Faculty of Dentistry, University of Porto.

Annual, 1st year of Dentistry Graduate (100 contact hours).

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Postgraduate

2007- Biostatistics I.

Faculty of Medicine, University of Porto.

Master Programme in Health Evidence and Decision

(7 ECTS).

2006- Biostatistics.

Faculty of Medicine and Faculty of Sciences, University of Porto.

Master Programme in Medical Informatics.

(5 ECTS).

June 2010- Biostatistics - Introduction to data analysis using SPSS.

Faculty of Medicine, University of Porto.

Summer School.

(24 contact hours).

June 2009- Introduction to Biostatistics using SPSS.

Faculty of Medicine, University of Porto.

Summer School.

(24 contact hours).

June 2007- Biostatistics.

Faculty of Medicine, University of Porto.

Summer School.

(24 contact hours).

Sep 2006- Biostatistics.

Hospital Maria Pia, Fundo Social Europeu.

Clinical Research methodology, Evidence based Medicine and Biostatistics course.

(24 contact hours).

Oct 2006- Biostatistics.

Hospital Maria Pia, Fundo Social Europeu.

Clinical Research methodology, Evidence based Medicine and Biostatistics course.

(24 contact hours).

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2004/2005- Biostatistics.

Faculty of Nutrition and Food Sciences of the University of Porto.

Master Programme in Clinical Nutrition.

(45 contact hours).

April 2005- Biostatistics.

Faculty of Medicine, University of Porto.

Clinical Research Methodology, Evidence Based Medicine and Biostatistics course.

(24 contact hours).

Feb 2004- Data Analysis.

Faculty of Medicine, University of Porto.

Clinical Research Methodology and Data Analysis course.

(24 contact hours).

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MSc committees

June 2010 - Joana Oliveira da Silva Ribeiro.

“Reliability of Visual Analysis by Neurophysiologists os Electroencephalograms in Hypoxic-

ischemic Patients.”

Master Programme in Health Evidence and Decision.

Faculty of Medicine, University of Porto.

March 2010 - José Cliver Bandeira de Albuquerque.

“Reprodutibilidade em Ginecologia e Obstetrícia. Concordância inter-observador na avaliação de

uma nova classificação do cardiotocograma intraparto.”

Master Programme in Health Evidence and Decision.

Faculty of Medicine, University of Porto.

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MSc advisory

July 2010 - Cátia Tatiana Pinto Moreira

“Avaliação de uma implementação do Sistema de Triagem de Manchester: Que realidade?.”

Master Programme in Medical Informatics.

Faculty of Medicine and Faculty of Sciences, University of Porto.

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Publications

Author of 14 full papers (5 of those as first author) published in periodicals indexed by Thomson Reuters

(ISI), 4 letters to the Editor published in periodicals indexed by Thomson Reuters (ISI), 5 publications in

periodicals not indexed by ISI but indexed by Medline, 4 other scientific publications in periodicals with

referee, 2 thesis (1 MSc and 1 PhD) and 9 abstracts.

Full papers in international scientific periodicals with referee (indexed by ISI)

1. Costa A, Santos C, Ayres-de-Campos D, Costa C, Bernardes J. Access to computerised analysis of

intrapartum cardiotocographs improves clinicians’ prediction of newborn umbilical artery blood pH.

BJOG. 2010 (in press). IF = 3.437

2. Costa-Santos C, Bernardes J, Ayres-de-Campos D, Costa A, Costa C. The limits of agreement and

the intra-class correlation coefficient may be inconsistent in the interpretation of agreement. J Clin

Epidemiol. 2010 (in press). IF = 2.896

3. Costa-Santos C, Antunes L, Souto A, Bernardes J. Assessment of disagreement: a new information

based approach. Ann Epidemiol. 2010; 20:552-558. IF = 2.621

4. Costa A, Ayres-de-Campos D, Machado AP, Santos CC, Bernardes J. Comparison of a computer

system evaluation of intrapartum cardiotocographic events and a consensus of clinicians. J Perinat

Med. 2010;38:191-195. IF = 1.234

5. Costa A; Ayres-de-Campos D; Costa F; Santos C; Bernardes J. Prediction of neonatal acidemia by

computer analysis of fetal heart rate and ST event signals. Am J Obstet Gynecol. 2009;201(5):464.e1-

6. IF = 3.453

6. Mota R, Costa F, Amaral A, Oliveira F, Costa Santos C, Ayres-De-Campos D. Skin adhesive versus

subcuticular suture for perineal skin repair after episiotomy--a randomized controlled trial. Acta

Obstet Gynecol Scand. 2009;88(6):660-6. IF = 1.356

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7. Antunes H, Santos C, Carvalho S. Serum leptin levels in overweight children and adolescents. Br J

Nutr. 2009;101(8):1262-6. IF = 2.764

8. Marques JM, Alonso I, Santos C, Silveira I, Olsson IA. The spatial learning phenotype of

heterozygous leaner mice is robust to systematic variation of the housing environment. Comparative

Med. 2009;59(2):129-38. IF = 1.089

9. Dinis-Ribeiro M, Correia RC, Santos C, Fernandes S, Palhares E, Silva RA, Amaro P, Areia M,

Costa Pereira A, Moreira-Dias L. Web-based system for training and dissemination of a

magnification chromoendoscopy classification. World J Gastroentero 2008;14:7086-7092. IF =

2.081

10. Costa-Santos C, Bernardes J, Vitányi P, Antunes L. Clustering Fetal Heart Rate Tracings by

Compression. Proceedings of 19th IEEE International Symposium of Computer-Based Medical

Systems CBMS 2006; 685-90 (ISI proceeding)

11. Merletti F, Richiardi L, Bertoni F, Ahrens W, Buemi A, Costa-Santos C, Eriksson M, Guenel P,

Kaerlev L, Jockel KH, Llopis-Gonzalez A, Merler E, Miranda A, Morales-Suarez-Varela MM,

Olsson H, Fletcher T, Olsen J. Occupational factors and risk of adult bone sarcomas: A multicentric

case-control study in Europe. Int J Cancer 2006; 118: 721-7. IF = 4.693

12. Costa Santos C, Costa Pereira A, Bernardes J. Agreement studies in obstetrics and gynaecology:

Inappropriateness, controversies and consequences. BJOG. 2005; 112 (5): 667-9. IF = 2.171

13. Ayres de Campos D, Costa Santos C, Bernardes J. Prediction of neonatal state by computer

analysis of fetal heart rate tracings: the antepartum arm of the SisPorto? multicentre validation

study. Eur J Obstet Gyn R B 2005; 118: 52-60. IF = 1.141

14. Costa Santos C, Ayres de Campos D, Costa Pereira A, Bernardes J. An Interactive web site for

research on fetal heart rate monitoring. Obstet Gynecol. 2000; 95(2):309-311. IF = 2.091

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Letters to the Editor published in international scientific periodicals with referee (indexed by ISI)

1. Costa-Santos C, Bernardes J. Differences and consequences in interobserver variation in

intrapartum fetal heart rate assessment. Letter to the editors. Am J Obstet Gynecol. 2009;200(6):e8. IF

= 3.453

2. Ayres-de-Campos D, Costa-Santos C, Bernardes J. Agreement on cardiotocogram interpretation

and clinical decision using the STAN guidelines. Letter to the editors. BJOG. 2009;116(11):1540-1. IF

= 3.101

3. Costa-Santos C, Bernardes J, Ayres de Campos D. Assessment and reporting of the reproducibility

of fetal heart rate monitoring. Letter to the editors. Am J Obstet Gynecol. 2008;198(3):343 IF = 3.453

4. Costa-Santos C, Bernardes J, Ayres de Campos D. Assessment and reporting of the reproducibility

of fetal heart rate monitoring. Letter to the editors. Am J Obstet Gynecol. 2008;198(3):343 IF = 3.453

Publications in scientific periodicals with referee (not indexed by ISI but indexed by Medline)

1. Abelha FJ, Santos CC, Barros H. Quality of life before surgical ICU admission. BMC Surgery

2007, 7:23.

2. Campos MA, Kent-Smith L, Costa Santos C. Effect of feeding competencies on the nutritional

status of children with cerebral plasy. Acta Med Port 2007; 20: 21-27.

3. Costa Santos C, Coutinho A, Cruz-Correia R, Ferreira A, Costa Pereira A E-learning at Porto

Faculty of Medicine. A Case Study for the Subject 'Introduction to Medicine'. Stud Health Technol

Inform. 2007;129:1366-71

4. Abelha FJ, Santos CC, Maia PC, Castro MA, Barros H. Quality of life after stay in surgical intensive

care unit. BMC Anesthesiol 2007; 24: 7-8.

5. Abelha F, Castro MA, Neves AM, Landeiro NM, Costa Santos C. Hypothermia in a surgical

intensive care unit. BMC Anesthesiol 2005; 5 (1): 7.

Other publications

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1. Abelha FJ, Castro MA, Landeiro MN; Neves AM; Santos CC. Mortality and Length of Stay in a

Surgical Intensive Care Unit. Revista Brasileira de Anestesiologia 2006; 56 (1): 34-45.

2. Costa Santos C, Teixeira-Pinto A, Costa Pereira A. Web-based learning at the Faculty of Medicine

of Oporto: description and evaluation of a student's Intranet. Proceedings of the 8th International

Conference of European University Information Systems. 2002;152-154.

3. Isabel Antunes, José Amat-Lopez, Cristina Vasconcelos, Mª Antónia Barros, Fernando Amado,

Cristina Santos, Altamiro Costa-Pereira e José Mesquita Guimarães. Estudo da hipersensibilidade

imediata e retardada a àcaros do pó em crianças com dermatite atópica. Boletim informativo

GPEDC. 1999; 13:31-35.

4. Costa Santos C, Ayres de Campos D, Costa Pereira A, Bernardes J. Utilização do Web Site de um

projecto de Investigação na Educação Médica. Educação Médica. 1998; 9(2):110-116.

Thesis

1. Cristina da Costa Santos. Statistical Methdos for Assessing Agreement of Measurements:

examples on obstetrics and Gynecology. Tese de Doutoramento. Programa de Doutoramento em

Investigação Clínica e em Serviços de Saúde. Universidade do Porto. 2010.

2. Cristina da Costa Santos. Sistemas de Informação baseados na Web: análise, desenho e

Implementação. Dissertação de Mestrado. Mestrado em Estatística e Gestão de Informação.

Universidade Nova de Lisboa. 2000.

Abstracts

1. Costa A, Costa-Santos C, Ayres-de-Campos D, Costa C, Bernardes J. Does access to computerized

cardiotocogram analysis affect the clinical prediction of newborn umbilical ph and apgar scores? J

Perinat Med 2009;37(Suppl I):257.

2. Costa A , Machado AP, Santos C, Ayres-de-Campos D, Bernardes J. Comparison of the evaluation

of cardiotocographic events by Omniview-SisPorto 3.5 and a consensus of clinicians. J Perinat Med

2007;35 (Suppl II):S63.

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3. Abelha F, Landeiro N, Neves A, Santos C, CastroM. Hypothermia in a surgical intensive care unit.

Crit Care 2005; 9: P298.

4. Antunes, H; Goncalves, S; Santos, C; Costa-Pereira, A; Tojo-Sierra, R; Aguiar, A. Should iron

requirements in first year of life be differentiated by gender?. J Pediatr Gastroenterol Nutr 2005; 40

(5): 699.

5. Antunes H, Gonçalves S, Santos C, Costa-Pereira A, Tojo-Sierra R, Aguiar R. Long-term

development after iron deficient anemia in infants. J Pediatr Gastroenterol Nutr. 2003;36(4):581.

6. Antunes H, Gonçalves S, Costa-Santos C, Costa-Pereira A, Tojo- Sierra R, Aguiar A. Iron

deficiency anaemia in infants: results from a follow-up study do not show development impairment

at eight years. Gut. 2003; 52 (Suppl6): S199.

7. Ayres-de-Campos D, Bernardes J, Reynolds A, Saraiva JP, Santos C, Pereira-Leite L. Computer

evaluation of internal versus external FHR monitoring in the minutes proceeding delivery. Int J

Gynecol Obstet. 2000;70(suppl 1;2):60-61.

8. Ayres- de-Campos D, Xavier P, Reynolds A, Guimarães M, Costa-Santos C, Patrício B. Ensaio

Randomizado da técnica de Misgav- Ladach modificada versus a técbica clássica na realização da

cesariana segmentar transversal. Livro de Resumos 1º Encontro Internacional dos Hospitais da

Ordem de Santiago 1999.

9. Xavier P, Ayres-de-Campos D, Reynolds A, Guimarães M, Costa-Santos C, Patrício B. A

randomised trial of the Misgav Ladach versus the classical technique for caesarean section:

preliminary results. Eur J Obstet Gynecol Reprod Bi 1999; 86:

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Oral Communications

1. 9th World Congress of Perinatal Medicine. Berlin, 2009, German. Does access to computerized

cardiotocogram analysis affect the clinical prediction of newborn umbilical ph and apgar

scores? Costa A, Costa-Santos C, Ayres-de-Campos D, Costa C, Bernardes J.

2. 8TH World Congress of Perinatal Medicine. Florence, 2007, Italy. Comparison of the

evaluation of cardiotocographic events by Omniview-SisPorto 3.5 and a consensus of clinicians.

Costa A , Machado AP, Santos C, Ayres-de-Campos D, Bernardes J.

3. 19th IEEE International Symposium of Computer-Based Medical Systems (CBMS), Salt

Lake City, 2006, USA. Clustering Fetal Heart Rate Tracings by Compression. Costa-Santos C,

Bernardes J, Vitányi P, Antunes L.

4. 25th International Symposium on Intensive Care and Emergency Medicine. Brussels, 2005,

Belgium. Hypothermia in a Surgical Intensive Care Unit. Abelha FJ, Landeiro NM, Neves AM,

Santos CC, Castro MA.

5. 8th International Conference, European University Information Systems. Porto, 2002,

Portugal. Web-based Learning at the Faculty of Medicine of Oporto: Description and Evaluation

of a Student's Internet. Costa-Santos C, Teixeira-Pinto A, Costa-Pereira A.

6. X Congresso Nacional de Educação Médica. Porto, 2000, Portugal. Utilização de uma Intranet

para o Ensino na Faculdade de Medicina da Universidade do Porto. Santos CC, Freitas JA, Costa-

Pereira A, Portugal.

7. 1º Encontro Internacional dos Hospitais da Ordem de Santiago. Sesimbra, 1999, Portugal.

Ensaio Randomizado da técnica de Misgav- Ladach modificada versus a técbica clássica na

realização da cesariana segmentar transversal. Ayres- de-Campos D, Xavier P, Reynolds A,

Guimarães M, Costa-Santos C, Patrício B.

8. XIV European Congress of Gynecologists and Obstetricians. Granada, 1999, Spain. A

Randomised Trial of the Misgav-Ladach versus the Calssical Technique for Cesarean section:

Preliminary Results. Xavier P, Ayres-de-Campos D, Reynolds A, Guimarães M, Costa-Santos C,

Patricio B.

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Posters

1. 25th International Symposium on Intensive Care and Emergency Medicine. Brussels, 2005,

Belgium. Hipothermia in a surgical Intensive Care Unit. Abelha FJ, Landeiro NM, Neves AM,

Santos CC, Castro MA.

2. 38th Annual Meeting of the European Society for Pediatric Gastroentrology, Hepatology

and Nutrition, European Society for Paediatric Gastroenterology Hepatology and

Nutrition (ESPGHAN). Porto, 2005, Portugal. Should iron requirements in first year of life be

differentiated by gender? Antunes, H; Goncalves, S; Santos, C; Costa-Pereira, A; Tojo-Sierra, R;

Aguiar, A. 01-04 Junho.

3. V Congresso Nacional de Bioética, Faculdade de Medicina da Universidade do

Porto. Porto, 2004, Portugal. A Sexualidade e os (Des)Afectos. Canário C, Gonzaga M, Seara A,

Brandão A, silva C, Santos C, Duarte I, Ricou M, Nunes R.