CURRICULUM VITAE PROF ANDREA FRUSTACI

DATI ANAGRAFICI

Nome: Andrea Frustaci

Cittadinanza: Italiana

Indirizzo Laboratori di Cardiologia Cellulare e Molecolare

INMI L. Spallanzani IRCCS Via Portuense, 292

C.A.P. 00149 Roma

Tel 06.55170520

E-mail biocard@inmi.it

TITOLI DI STUDIO E FORMAZIONE UNIVERSITARIA

1971 Diploma di maturità classica, Roma.

1977 Laurea in Medicina e Chirurgia (110/110 cum Laude),

Università Cattolica del Sacro Cuore, Roma.

1980 Specializzazione in Cardiologia, Università Cattolica del

Sacro Cuore, Roma.

CURRICULUM ACCADEMICO

1982 Research Fellowship presso il King's College Hospital

(Dr. P. Richardson) doce ha appreso la tecnica della

biopsia endomiocardica

1983-1991 Research Fellowship presso il National Heart Hospital

(Dr. E.G.J. Olsen) ed il Brompton Hospital di Londra

dove ha appreso l‟nterpretazione istopatologica delle

biopsie endomiocardiche

1983-2005 Ricercatore Universitario in Cardiologia (settore

scientifico disciplinare MED/11) presso nella Facoltà di

Medicina e Chirugia-Policlinico "A. Gemelli"

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2000-2006 “Visiting Associate Professor of Medicine” presso il New

York Medical College (New York- USA).

2004 Idoneità per professore associato in Cardiologia

Marzo 2005 Professore associato presso l‟Università la Sapienza di

Roma, I Facoltà di Medicina e Chirurgia,

Dipartimento “Cuore e Grossi Vasi Attilio

Reale”.

2008 Conferma nel ruolo di Professore Associato di

Cardiologia presso la medesima Facoltà.

Dicembre 2008-oggi Affiliazione presso l‟attuale Dipartimento di “Scienze

Cardiovascolari, Respiratorie,

Nefrologiche e Geriatriche”, Università La

Sapienza, I Facoltà di Medicina e

Chirurgia.

ATTIVITA’ CLINICA

1983-1993 Assistente presso l'Istituto di Cardiologia del Policlinico

A Gemelli, nella Facoltà di Medicina e Chirugia-

Policlinico "A. Gemelli"

1993-2005 Aiuto presso l'Istituto di Cardiologia nella Facoltà di

Medicina e Chirurgia del Policlinico A Gemelli.

1983-1990 Attività assistenziale presso l‟Unità Coronarica del

Policlinico Gemelli occupandosi della diagnostica non-

invasiva ed invasiva e del trattamento dell‟infarto

miocardico e delle sindromi coronariche acute.

1990-2001 Attività assistenziale presso il Reparto di Cardiologia

dello stesso nosocomio, occupandosi in particolare dello

scompenso cardiaco e delle sue cause incluse la

cardiopatia ischemica le cardiomiopatie e le miocarditi.

1983-2005 Istituzione e direzione del Laboratorio di Biopsia

Endomiocardica, presso l'Istituto di Cardiologia

dell‟Università Cattolica del Sacro Cuore, dedicato

all‟esecuzione dell‟indagine bioptica, all‟interpretazione

istomorfologica dei frammenti bioptici ottenuti ed

all‟applicazione di metodiche di biologia molecolare su

tessuto miocardico congelato. Tale laboratorio ha

espresso continuità operativa fornendo in media 150

procedure diagnostiche l'anno.

2005-2008 Attività assistenziale presso il Dipartimento “Cuore e

Grossi Vasi Attilio Reale dell‟Univeristà la Sapienza di

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Roma, I Facoltà di Medicina e Chirurgia.

2008-oggi Attività assistenziale presso il Dipartimento “Scienze

Cardiovascolari, Respiratorie, Nefrologiche e

Geriatriche” dell‟Univeristà la Sapienza di Roma, I

Facoltà di Medicina e Chirurgia.

2005-oggi Istituzione e direzione dei Laboratori di Cardiologia

Cellulare e Molecolare presso l‟IRCSS L. Spallanzani di

Roma.

ATTIVITA’ SCIENTIFICA

1983-1986 Direzione dell‟Unità Operativa del C.N.R. per il progetto

finalizzato SP4 "Malattie degenerative".

1999-2000 Responsabile dell‟Unità di Ricerca dell‟Università

Cattolica del Sacro Cuore nell‟ambito del Progetto

“Myocarditis: impact of etiological diagnosis based upon

molecular and immunologic findings” finanziato dal

Ministero dell‟Università e della Ricerca Scientifica e

Tecnologica.

2000-2004 Co-Principal Investigator, il N.I.H. RFA Grant per la

ricerca dal titolo “Oxidative stress and Diabetic

Cardiomyopathy” in collaborazione con il Prof. Piero

Anversa.

2001 Finanziamenti alla ricerca dal Ministero della Salute per

lo studio della morte improvvisa giovanile, in

collaborazione con la Prof.ssa Priori (Università di Pavia)

ed il Prof. Thiene (Università di Padova), e per lo studio

delle metalloproteinasi nella cardiomiopatia dilatativa in

collaborazione con la Prof,ssa Arbustini (Università di

Pavia).

2003

2004

2005-2007

Finanziamento Telethon (Grant GGP030344) per il

progetto „Fabry Cardiomyopathy: metabolic impact of

enzyme replacement therapy‟

Responsabile di unità operativa per ricerca sanitaria

finalizzata finanziata dal Ministero della Salute, mediante

la Regione Veneto (nota prot. N. 11834-MdS.DGRSTT

del !7!”/2004) dal titolo: Cardiomiopatie infiammatorie:

eziopatogenesi e trattamenti endocrino-farmacologici per

il recupero della funzione contrattile.

Principal Investigator del grant Telethon n.GGP05264 dal

titolo “Fabry cardiomyopathy: myocardial gene

expression profiling in responders and non responders to

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enzyme-replacement therapy”.

2008-2009 Finanziamento alla ricerca dal Ministero della Salute per

un progetto bando ex art 56 (2008-2009) dal titolo:

Cardiomiopatiaq infiammatoria HIV-relata e non:

identificazione degli agenti causali e dei meccanismi

patogenetici ai fini di una terapia mirata.

2009-2012 Sono in corso di finanziamento tre progetti del ministero della

Salute:

1) Bando Malattie Rare Ministero della Salute. Titolo del progetto: Enzyme replacement

therapy in the progression of Fabry's disease cardiomyopathy: morphologic biochemical and

molecular characterization (unità operativa)

2) Multicenter randomized study on the efficacy of immunosuppression on

patients with virus-negative myocarditis. RF 2009-1549885 (principal

invastigator)

3) Structural mechanisms of right ventricular remodelling in patients with

pulmonary hypertension (RF 2009) (unità operativa).

ATTIVITA’ DIDATTICA

1983-2005 Incarico di insegnamento presso la Scuola di

Specializzazione in Cardiologia dell‟Università Cattolica

del Sacro Cuore di Roma

2005-oggi Incarico di insegnamento presso la Scuola di

Specializzazione in Cardiologia II scuola dell‟Università

La Sapienza di Roma I Facoltà di Medicina e Chirurgia-

2006-2010 Docente di “Medicina Interna” presso il corso di Laurea

in “Tecnici di Laboratorio biomedico” dell‟Università La

Sapienza di Roma, sede San Raffaele Pisana.

PREMI E RICONOSCIMENTI:

5

1987 "Young Scholar Award" al 53° Congresso dell'

American College of Chest Physicians per il

lavoro "Myocardial magnesium content in primary

ventricular tachycardia. Relation between myocardial

Mg, histology and antiarrhythmic response to Mg infusion".

APPARTENENZA A SOCIETÀ SCIENTIFICHE

1989 Fellow dell' American College of Chest Physicians.

1989-1993 Membro del Council on Cardiomyopathies of the

'International Society and Federation of Cardiology

1999 Membro del Council on Cardiomyopathies of the

'International Society and Federation of Cardiology.

ATTIVITÀ EDITORIALE

1996 Reviewer della rivista CHEST .

2000-2005 Membro dell‟Editorial Board dell‟Italian Heart Journal

2005-oggi Reviewer di Circulation, JACC, New England Journal of

Medicine, European Heart Journal, European Journal of

Heart Failure, American Journal of Cardiolog, Lancet,

Journal of Echocardiography, Journal of Infectious

diseases.(allega a riguardo ECM credits da NEJM ed

inclusione del candidato fra i major reviewers della

stessa rivista.

Il Prof Frustaci ha un‟ottima conoscenza della lingua inglese scritta e parlata e ha realizzato le

pubblicazioni scientifiche di seguito elencate.

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PUBBLICAZIONI SU RIVISTE SCIENTIFICHE CON IMPACT FACTOR

IMPACT FACTOR TOTALE=845

NUMERO DI CITAZIONI=3450

CITAZIONI/ANNO=115

CITAZIONI/LAVORO=31.94

CITAZIONI/AUTORE=767.35

H-INDEX=25

1. Frustaci A, Rebuzzi AG, Schiavoni G, Coppola E, Manzoli U. Potassium depletion. A gap

between cardiac and skeletal muscle damage? Chest 1982;81:528-529.

2. Frustaci A, Anti M, Fedeli G, Devitis I, Rapaccini GL. Hypomagnesaemic hypocalcemia with

high serum IPTH level in caeliac disease: a case report Ital. J. Gastroenterol. 1983;15:181-182

3. Frustaci A, Pennestrì F, Scoppetta C. Myocardial damage due to hypokalemia and

hypophosphatemia. Postgraduate Med. J. 1984;60: 679-681.

4. Magarò M, Ceresia G, Frustaci A. Arthritis of the middle ear in ankylosing spondylitis. Annals

of the Rheumatic diseases 1984;43:655-659.

5. Frustaci A Hypokalemic myocytolysis and rhythm disturbances. Chest 1984;85:836.

6. Frustaci A, Loperfido F, Pennestrì F. Hypertrophic cardiomyopathy simulating an infiltrative

myocardial disease. Br. Heart J. 1985,54.329-332.

7. Frustaci A, Caldarulo M, Cittadini A, Lanza GA, Bellocci F. Myocardial magnesium content in

primary ventricular tachycardia. Relation between myocardial Mg, histology and antiarrhythmic

response to Mg infusion. CHEST 1987;92:985.

8. Frustaci A, Caldarulo M, Schiavoni G, Bellocci F, Manzoli U, Cittadini A. Myocardial

magnesium content, histology and antiarrhythmic response to magnesium infusion. Lancet

1987;2:1019.

9. Frustaci A, Abdulla AK, Possati GF, Manzoli U. Persisting hypereosinophilia and myocardial

activity in the fibrotic stage of endomyocardial disease. CHEST 1989, 96:674-675

10. Frustaci A. Right ventricular dysplasia versus idiopathic dilated cardiomyopathy. Eur Heart J

1989;10 Suppl D:92-94.

11. Antonelli Incalzi A, Gemma A, Frustaci A, et al. Low atrial tachycardia as primary cause of the

heart failure complicating congestive cardiomyopathy. Acta Cardiologica 1989;44:335-339.

12. Abdulla AK, Frustaci A, Martinez JE, Florio RA, Sommerville J, Olsen EGJ.

Echocardiography and pathology of left ventricular "false tendons". CHEST 1990;98:129-132.

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13. Manzoli U, Rossi E, Littarru GP, Frustaci A, Lippa S et al. Coenzime Q10 in dilated

cardiomyopathy. Int J Tissue React 1990;12:173-8.

14. Frustaci A, Caldarulo M, Di Rienzo V, Russo MA, Gentiloni N. Antiarrhythmic effect of H2

Antihistamines. CHEST 1991;99.262-263.

15. Frustaci A, Loperfido F, Gentiloni N, Caldarulo M, Morgante E, Russo MA. Catecholamine-

induced cardiomyopathy in multiple endocrine neoplasia. A histologic, ultrastructural, and

biochemical study. CHEST 1991;99.382-385.

16. Frustaci A, Caldarulo M et al.Cardiac biopsy in patients with "primary" atrial fibrillation.

Histologic evidence of occult myocardial diseases. CHEST 1991;100:303-306.

17. Frustaci A, Russo MA, et al. Reversible dilated cardiomyopathy due to growth hormone

deficiency. Am Journal of Clinical Pathology 1992;97:503-511.

18. Melina D, Colivicchi F, Guerrera G, Melina G, Frustaci A, Caldarulo M, Guerrera

C.Prevalence of left ventricular hypertrophy and cardiac arrhythmias in borderline hypertension.

Am J Hypertens. 1992;5:570-3.

19. Frustaci A, et al. Reversible dilated cardiomyopathy due to growth hormone deficiency.

CHEST 1992;102:326-327.

20. Frustaci A, Maseri A. Localized left ventricular aneurysms with normal global function caused

by myocarditis. Am J Cardiol 1992 ;70:1221-24.

21. Frustaci A, Caldarulo M, Pagliari G. Coronary angyodysplasia causing left ventricular shunt

and myocardial ischemia. Am Heart J 1993;125:889-891.

22. Mirabella M, Servidei S, Manfredi G, Ricci E, Frustaci A, Bertini E, Rana M, Tonali

P.Cardiomyopathy may be the only clinical manifestation in female carriers of Duchenne muscular

dystrophy. Neurology. 1993;43:2342-5.

23. Frustaci A, Caldarulo M, Pagliari G. Coronary angyodysplasia causing left ventricular shunt

and myocardial ischemia. Am Heart J 1993;125:889-891.

24. Zeppilli P, Santini C, Palmieri V, Vannicelli R, Giordano A, Frustaci A. Role of Myocarditis

in Athletes with Minor Arrhythmias and/or Echocardiographic Abnormalities .CHEST

1994;106:373-80.

25. Frustaci A, Lemmo G, Nuzzo G. Basilic Transvenous Biopsy for Investigation of Superior

Vena Caval Syndrome. CHEST 1994;106:1925-26 .

26. Frustaci A, Bellocci F, Olsen EGJ. Results of Biventricular Endomyocardial Biopsy in

Survivors of Cardiac Arrest with Apparently Normal Hearts. Am J Cardiol 1994 ;74:890-895.

27. Booth DR, Tan SY, Hawkins PN, Pepys MB, Frustaci A. A Novel Variant of Transthyretin ,

59thr to lys, Associated with Autosomal Dominant Cardiac Amyloidosis in an Italian Family.

Circulation 1995;91:962-967.

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28. Frustaci A, Cameli S, Zeppilli P. Byopsy evidence of atrial myocarditis in an athlete developing

transient sino-atrial disease. CHEST 1995; 108: 1460-1462.

29. Frustaci A, Zurlo A, Perrone GA, Russo A, Caldarulo M, Russo MA. Morphometry and

GH/IGF-1 axis deficiency may identify a form of dilated cardiomyopathy which is corrected by

recombinant human growth hormone (rHGH). Ann N Y Acad Sci. 1995;752:422-5.

30. Frustaci A, Caldarulo M et al.Acute myocarditis and left ventricular aneurysm as presentation

of Systemic Lupus Erythematosus. CHEST 1996;109:282-284

31. Minotti G, Mancuso C, Frustaci A, Mordente A, Santini SA, Calafiore AM, Liberi G, Gentiloni

N. Paradoxical inhibition of cardiac lipid peroxidation in cancer patients treated with doxorubicin.

Pharmacologic and molecular re-appraisal of anthracycline cardiotoxicity. J Clin Investigation

1996;98:650-661.

32. Zeppilli P, Santini C, Cameli S, Dello Russo A, Picani C, Giordano A, Frustaci A. Healed

Myocarditis as a Cause of Ventricular Repolarization Abnormalities in Athlete's Heart. Intern J

Sports Med 1997;18:213-16.

33. Frustaci A, Gentiloni N, Russo MA. Growth Hormone in the treatment of Dilated

Cardiomyopathy. N Engl J Med 1996;335:672-674.

34. Frustaci A, Chimenti C, Pieroni M. Idiopathic Myocardial Vasculitis Presenting as Restrictive

Cardiomyopathy. CHEST 1997; 111: 1462-1464.

35. Frustaci A, Chimenti C, Bellocci F, Morgante E, Russo MA, Maseri A. Histological Substrate

of Atrial Biopsies in Patients with Lone Atrial Fibrillation. Circulation 1997; 96: 1180-1184.

36. Frustaci A, Chimenti C, Natale L. Right ventricular aneurysm associated with advanced

hypertrophic cardiomyopathy. CHEST 1998; 113:552-554

37. Zeppilli P, Dello Russo A, Santini C, Palmieri V, Natale L, Giordano A and Frustaci A. In vivo

detection of coronary Artery anomalies in Asymptomatic Athletes by Ehocardiographic Screening.

CHEST 1998;114:89-93.

38. Frustaci A, Gentiloni N, Chimenti C, Natale L, Gasbarrini G, Maseri A. Necrotizing

Myocardial Vasculitis in Churg-Strauss Syndrome: Clinico-Histologic Evaluation of Steroids and

immunosuppressive Therapy. CHEST 1998, 114;1484-1489.

39. Frustaci A, Chimenti C, Maseri A. Global bi-ventricular dysfunction in patients with

asymptomatic coronary artery disease may be caused by myocarditis. Circulation

1999;99:1295-1299.

40. Frustaci A, Chimenti C, Setoguchi M, Guerra S, Corsello S, Crea F, Leri A, Kajstura J,

Anversa P, Maseri A. Cell death in acromegalic cardiomyopathy. Circulation. 1999;99:1426-

34.

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41. Frustaci A, Magnavita N, Chimenti C, Caldarulo M, Sabbioni E, Pietra R, Cellini C,

Possati GF, Maseri A. Marked elevation of myocardial trace elements in idiopathic dilated

cardiomyopathy compared to secondary cardiac dysfunction. J Am Coll Cardiol

1999;33:1578-1583.

42. Frustaci A, Chimenti C, Maseri A. Reply to “Mercury and idiopathic dilated

cardiomyopathy”. J Am Coll Cardiol 2000; 35: 819.

43. Frustaci A, Chimenti C, Pieroni M, Gentiloni N. Giant cell myocarditis responding to

immunosuppressive therapy. CHEST 2000; 117:905-907.

44. Frustaci A, Chimenti C, Pieroni M. Coronary angiodysplasia of epicardial and intramural

vessels. CHEST 2000;118(5):1511-3.

45. Frustaci A, Chimenti C, Pieroni M. Prognostic significance of left ventricular aneurysms

with normal global function caused by myocarditis. CHEST 2000;118(6):1696-702

46. Frustaci A, Kajstura J, Chimenti C, Jakoniuk I, Leri A, Maseri A, Nadal-Ginard B, Anversa

P. Myocardial cell death in human diabetes. Circ Res. 2000;87(12):1123-32.

47. Chimenti C, Calabrese F, Thiene G, Pieroni M, Maseri A, Frustaci A. Inflammatory left

ventricular microaneurysms as a cause of apparently idiopathic ventricular tachyarrhythmias.

Circulation. 2001;104:168-73.

48. Frustaci A, Chimenti C, Ricci R, Natale L, Russo MA, Pieroni M, Eng CM, Desnick RJ.

Improvement in cardiac function in the cardiac variant of Fabry's disease with galactose-

infusion therapy. N Engl J Med. 2001;345:25-32.

49. Chimenti C, Pieroni M, Frustaci A. Endomyocardial fibrosis mimicking a dilated

cardiomyopathy in a child. Heart. 2001;86:73.

50. Frustaci A, Pieroni M, Chimenti C.Late-onset primary LVH HCM versus cardiac fabry

variant. J Am Coll Cardiol. 2002;39:1405-6.

51. Frustaci A, Cuoco L, Chimenti C, Pieroni M, Fioravanti G, Gentiloni N, Maseri A,

Gasbarrini G. Celiac disease associated with autoimmune myocarditis. Circulation

2002;105:2611-8.

52. Frustaci A, Calabrese F, Chimenti C, Pieroni M, Thiene G, Maseri A. Lone HCV

myocarditis responsive to immunosuppressive therapy. CHEST. 2002;122:1348-56.

53. Frustaci A, Chimenti C, Calabrese F, Pieroni M, Thiene G, Maseri A. Immunosuppressive

therapy for active lymphocytic myocarditis: virologic and immunologic profile of responders

vs non-responders. Circulation 2003;107:857-63.

54. Chimenti C, Kajstura J, Torella D, Urbanek K, Heleniak H, Colussi C, Di Meglio F, Nadal-

Ginard B, Frustaci A, Leri A, Maseri A, Anversa P.Senescence and Death of Primitive Cells

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and Myocytes Leads to Premature Cardiac Aging and Heart Failure. Circ Res. 2003 Oct

3;93(7):604-13.

55. Frustaci A, Pieroni M, Chimenti C. Immunosuppressive therapy in inflammatory

cardiomyopathy. Eur Heart J Suppl January 2003.

56. Pieroni M, Chimenti C, Ricci R, Sale P, Russo MA, Frustaci A. Early Detection Of Fabry

Cardiomyopathy By Tissue Doppler Imaging. Circulation. 2003;107:1978-84.

57. Chimenti C, Pieroni M, Maseri A, Frustaci A. Histologic findings in patients with clinical

and instrumental diagnosis of sporadic Arrhythmogenic Right Ventricular Dysplasia. J Am

Coll Cardiol. 2004;43:2305-13.

58. Chimenti C, Pieroni M, Antuzzi D, Morgante E, Russo MA, Maseri A, Frustaci A.

Prevalence of Fabry Disease in female patients with hypertrophic cardiomyopathy.

Circulation 2004. 31;110:1047-53.

59. Calabrese F, Carturan E, Chimenti C, Pieroni M, Agostini C, Angelini A, Crosato M,

Valente M, Boffa GM, Frustaci A, Thiene G. Over-expression of Tumor Necrosis Factor

(TNF)- and TNF- receptor I in human viral myocarditis: clinico-pathologic correlations.

Mod Pathol. 2004;17:1108-18.

60. Pieroni M, Chimenti C, Russo A, Russo MA, Maseri A, Frustaci A. Tissue Doppler in Fabry

disease. Review. Curr Opin Cardiol. 2004;19:452-457.

61. Chimenti C, La Penna E, Pieroni M, San Vito F, Alfieri O, Maseri A, Frustaci A. Coronary

and valve angiodysplasia unmasked by eosinophilic vasculitis and endomyocarditis. CHEST

2004 Nov;126:1700-3.

62. Pieroni M, Cavallaro R, Chimenti C, Smeraldi E, Frustaci A. Clozapine-induced

hypersensitivity myocarditis. CHEST 2004;126:1703-5.

63. Chimenti C, Russo A, Pieroni M, Calabrese F, Verardo R, Thiene G, Russo MA, Maseri A,

Frustaci A. Intramyocyte detection of Epstein-Barr virus genome by laser capture

microdissection in patients with inflammatory cardiomyopathy. Circulation. 2004

7;110:3534-9.

64. Pieroni M, Chimenti C, Frustaci A. Letter regarding article by Nanthakumar et al,

"electrophysiological findings in adolescents with atrial fibrillation who have structurally

normal hearts". Circulation. 2005;111:e27; author reply e27.

65. Chimenti C, Pieroni M, Frustaci A. Letter regarding article by Abbate et al, "widespread

myocardial inflammation and infarct-related artery patency". Circulation. 2005;111:e17;

author reply e17.

66. Chimenti C, Pieroni M, Russo A, Sale P, Russo

MA, Maseri

A, Frustaci

A. Laser

microdissection in clinical cardiovascular research. CHEST 2005;128:2876-2881.

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67. Frustaci A, Priori SG, Pieroni M, Chimenti C, Napolitano C, Rivolta I, Sanna T, Bellocci F

and MA Russo. Cardiac histologic substrate in patients with clinical phenotype of Brugada

syndrome. Circulation 2005;112:3680-7.

68. Pieroni M, Chimenti C, Frustaci A. “Hissing snake” left ventricle. Thrombotic phase of

hypereosinophilic endomyocardial disease. Eur Heart J 2006;27:778.

69. Frustaci A, Pieroni M, Chimenti C. Immunosuppressive treatment of chronic non-viral

myocarditis. Ernst Schering Res Found Workshop. 2006; 55:343-51.

70. Chimenti C, Pieroni M, Frustaci A. Myocarditis: when to suspect and how to diagnose it in

athletes. Journal of Cardiovascular Medicine 2006 Apr;7(4):301-6. Review .

71. Cooper LT, Virmani R, Chapman NM, Frustaci A, Rodeheffer RJ, Cunningham MW,

McNamara DM. National Institute of Health-Sponsored Workshop on Inflammation and

Immunity in Dilated cardiomyopathy. Mayo Clin Proc 2006;81:199-204.

72. Decobelli F, Pieroni M, Esposito A, Chimenti C, Belloni E, Mellone R , Canu T, Perseghin

G , Gaudio C , Maseri A , Frustaci A, Del Maschio A. Delayed gadolinium-enhanced

cardiac magnetic resonance in patients with chronic myocarditis presenting with heart failure

or recurrent arrhythmias. JACC 2006 Apr 18;47(8):1649-54.

73. Frustaci A, Chimenti C, Pieroni M, salvatori L, Morgante E, Sale P, Ferretti E, Petrangeli E,

Gulino A and MA Russo. Cell death, proliferation and repair in humen myocarditis

responding to immunosuppressive therapy. Modern Pathology 2006;19(6):755-65.

74. Pieroni M, Chimenti C, F De Cobelli , E Morgante , Gaudio C, M A Russo, Frustaci A.

Fabry cardiomyopathy: echocardiographic detection of endomyocardial glycosphingolipids

compartmentalization. JACC 2006 Apr 18;47:1663-71.

75. Chimenti C, Pieroni M, Frustaci A. Myocarditis: when to suspect and how to diagnose it in

athletes. Journal of Cardiovascular Medicine 2006 Apr;7(4):301-6. Review .

76. Frustaci A, Verardo R, Caldarulo M, Acconcia MC, Russo MA and Chimenti C. Myocarditis

in hypertrophic cardiomyopathy patients presenting acute clinical deterioration. Eur Heart J

2007; 28: 733-740.

77. Chimenti C, Del Nonno F, Topino S, Abbate I, Licci

S, Paglia

MG, Capobianchi

MR,

Petrosillo N, Frustaci A. Fatal myocardial coinfection by Toxoplasma Gondii and Parvovirus

B19 in an HIV patient. AIDS 2007; 21(10):1386-1388.

78. Frustaci A, Verardo R, Sale P, Toscano F, Critelli G, Russo MA, Chimenti C.

Hypersensitivity myocarditis induced by beta-blockers: an unexpected cause of abrupt

deterioration in hypertrophic cardiomyopathy. Intensive Care Med 2007; 13:380-8.

79. Chimenti C, Morgante E, Critelli G, Russo MA, Frustaci A. Coronary artery bypass grafting

for Fabry‟s disease: veins more suitable than arteries? Hum Pathol 2007; 38(12):1864-7.

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80. Frustaci A, Chimenti C. Images in cardiovascular medicine. Cryptogenic ventricular

arrhythmias and sudden death by Fabry disease: prominent infiltration of cardiac conduction

tissue. Circulation 2007; 116(12):e350-1.

81. Cooper LT, Baughman KL, Feldman AM, Frustaci A, Jessup M, Kuhl U, Levine GN,

Narula J, Starling RC, Towbin J, Virmani R. The role of endomyocardial biopsy in the

management of cardiovascular disease: A Scientific Statement from the American Heart

Association, the American College of Cardiology, and the European Society of Cardiology

Endorsed by the Heart Failure Society of America and the Heart Failure Association of the

European Society of Cardiology. Eur Heart J. 2007; 28(24):3076-93.

82. Cooper LT, Baughman KL, Feldman AM, Frustaci A, Jessup M, Kuhl U, Levine GN, Narula

J, Starling RC, Towbin J, Virmani R; American Heart Association; American College of

Cardiology, and the European Society of Cardiology. The role of endomyocardial biopsy in

the management of cardiovascular disease: a scientific statement from the American Heart

Association, the American College of Cardiology, and the European Society of Cardiology.

Circulation. 2007 Nov 6;116(19):2216-33.

83. Cooper LT, Baughman KL, Feldman AM, Frustaci A, Jessup M, Kuhl U, Levine GN, Narula

J, Starling RC, Towbin J, Virmani R; American Heart Association; American College of

Cardiology, and the European Society of Cardiology, Heart Failure Society. The role of

endomyocardial biopsy in the management of cardiovascular disease: a scientific statement

from the American Heart Association, the American College of Cardiology, and the

European Society of Cardiology. Endorsed by the Heart Failure Society of America and the

Heart Failure Association of the European Society of Cardiology. J Am Coll Cardiol. 2007

Nov 6;50(19):1914-31.

84. Chimenti C, Morgante E, Critelli G, Russo MA, Frustaci A. Coronary artery bypass grafting

for Fabry‟s disease: veins more suitable than arteries?. Hum Pathol 2007; 38:1864-7.

85. Chimenti C, Hamdani N, Boontje NM, DeCobelli F, Esposito A, Bronzwaer JGF, Stienen

GJM, Russo MA, Paulus WJ, Frustaci A, van der Velden J. Myofilament Degradation and

Dysfunction in Human Cardiomyocytes with Fabry Disease. Am J Pathol 2008;172:1482-90.

86. Chimenti C, Agrusta M, Cioppa A, Campopiano E, Rubino P, Frustaci A.Auto-reactive myocarditis

after percutaneous closure of an atrial septal defect. Intensive Care Med. 2008

Nov;34(11):2121-2.

87. Esposito A, De Cobelli F, Perseghin G, Pieroni M, Belloni E, Mellone R, Canu T, Gentinetta F, Scifo P,

Chimenti C, Frustaci A, Luzi L, Maseri A, Del Maschio A.Impaired left ventricular energy

metabolism in patients with Hypertrophic Cardiomyopathy is related to the extension of

Fibrosis at Gadolinium Delayed Enhanced MR Imaging. Heart. 2008 Aug 15. [Epub ahead

of print]

88. Chimenti C,Morgante E, Tanzilli G, E Mangieri, G Critelli, C Gaudio, MA Russo, A

Frustaci. Angina in Fabry‟s disease reflects coronary small vessel disease. Circulation Heart

Failure 2008;1:161-169.

13

89. Chimenti C, Frustaci A. Histopathology of myocarditis. Review. Diagnostic Histopathology

2008;14:401-407.

90. Mehta A, Beck M, Kampmann C, Frustaci A, Germain DP, Pastores GM, Sunder-Plassmann

G. Enzyme replacement therapy in Fabry disease: comparison of agalsidase alfa

and agalsidase beta. Mol Genet Metab. 2008 Sep-Oct;95(1-2):114-5. Epub 2008 Aug 12

91. Esposito A, De Cobelli F, Perseghin G, Pieroni M, Belloni E, Mellone R, Canu T,

Gentinetta F, Scifo P, Chimenti C, Frustaci A, Luzi L, Maseri A, Maschio AD. Impaired

left ventricular energy metabolism in patients with hypertrophic

cardiomyopathy is related to the extension of fibrosis at delayed gadolinium-

enhanced magnetic resonance imaging. Heart. 2009 Mar;95(3):228-33. Epub 2008

Aug 15.

92. De Cobelli F, Esposito A, Belloni E, Pieroni M, Perseghin G, Chimenti C, Frustaci A, Del

Maschio A. Delayed-enhanced cardiac MRI for differentiation of Fabry's

disease from symmetric hypertrophic cardiomyopathy. AJR Am J Roentgenol.

2009 Mar;192(3):W97-102.

93. Frustaci A, Russo MA, Chimenti C. Structural myocardial abnormalities in

asymptomatic family members with Brugada syndrome and SCN5A gene

mutation. Eur Heart J. 2009 Jul;30(14):1763. Epub 2009 May 2.

94. Frustaci A, Russo MA, Chimenti C. Randomized study on the efficacy of

immunosuppressive therapy in patients with virus-negative inflammatory

cardiomyopathy: the TIMIC study. Eur Heart J. 2009 Aug;30(16):1995-2002.

95. Chimenti C, Morgante E, Tanzilli G, Mangieri E, Critelli G, Gaudio C, Russo MA, Frustaci

A. Angina in fabry disease reflects coronary small vessel disease. Circ Heart

Fail. 2008 Sep;1(3):161-9

96. Elia L, Contu R, Quintavalle M, Varrone F, Chimenti C, Russo MA, Cimino V, De Marinis

L, Frustaci A, Catalucci D, Condorelli G. Reciprocal regulation of microRNA-1 and

insulin-like growth factor-1 signal transduction cascade in cardiac and skeletal

muscle in physiological and pathological conditions. Circulation. 2009 Dec

8;120(23):2377-85. Epub 2009 Nov 23.

97. Chimenti C, Russo MA, Carpi A, Frustaci A. Histological substrate of human atrial

fibrillation. Biomed Pharmacother. 2010 Mar;64(3):177-83.

98. Scarpa M, Frustaci A. Novel therapies and future perspectives. Int J Clin Pharmacol Ther.

2009;47 Suppl 1:S109-10.

99. Frustaci A. Cytopathic pathways of enteroviral myocardial infection. Eur Heart J. 2010

Mar;31(6):637-9. Epub 2010 Jan 26.

100. Carbone I, Francone M, Chimenti C, Galea N, Russo M, Frustaci A. Images in

cardiovascular medicine: Right ventricular late enhancement as a magnetic resonance marker

of glycogen storage disease. Circulation. 2010 Jul 13;122(2):189-90.

14

101. Chimenti C, Russo MA, Frustaci A. Atrial biopsy evidence of Fabry disease causing lone

atrial fibrillation. Heart. 2010 Nov;96(21):1782-3. Epub 2010 Aug 23.

102. Chimenti C, Sale P, Verardo R, Cicalini S, Petrosillo N, Russo MA, Fedele F, Frustaci

A. High prevalence of intramural coronary infection in patients with drug-resistant cardiac

syndrome X: comparison with chronic stable angina and normal controls. Heart. 2010

Dec;96(23):1926-31. Epub 2010 Oct 3. Erratum in: Heart. 2010 Dec;96(24):2045

103. Pieruzzi F, Pieroni M, Chimenti C, Frustaci A, Sarais C, Cecchi F; Area Cardiologica-

Advisory Board Plan Multidisciplinare "Diagnosi e Follow-up Malattia di

Fabry".Cardiological follow-up in patients with Fabry disease. G Ital Cardiol

(Rome). 2010 Jul-Aug;11(7-8):566-72. Review.

104. Carbone I, Francone M, Galea N, Benedetti G, Frustaci A. Images in cardiology. Computed-

tomography and magnetic resonance imaging assessment of traumatic left anterior descending coronary

dissection causing acute myocardial infarction. J Am Coll Cardiol. 2011 Jan 11;57(2):e3

105. Colussi C, Rosati J, Straino S, Spallotta F, Berni R, Stilli D, Rossi S, Musso E, Macchi

E, Mai A, Sbardella G, Castellano S, Chimenti C, Frustaci A, Nebbioso A, Altucci L,

Capogrossi MC, Gaetano C. Nε-lysine acetylation determines dissociation from GAP

junctions and lateralization of connexin 43 in normal and dystrophic heart. Proc Natl Acad

Sci U S A. 2011 Feb 15;108(7):2795-800. Epub 2011 Jan 31

106. . Frustaci A, Lanfranchi G, Bellin M, Chimenti C. Coronary telangiectasia associated

with hypertrophic cardiomyopathy. Eur J Heart Fail. 2012 Dec;14(12):1332-7. doi:

10.1093/eurjhf/hfs125. Epub 2012 Aug 5. 107.

107. Frustaci A, Morgante E, Antuzzi D, Russo MA, Chimenti C Inhibition of

cardiomyocyte lysosomal activity in hydroxychloroquine cardiomyopathy.. Int J Cardiol.

2012 May 17;157(1):117-9. doi: 10.1016/j.ijcard.2012.03.112. Epub 2012 Apr 4.

108. Brisinda D, Sorbo AR, Venuti A, Ruggieri MP, Manna R, Fenici P, Wallukat G,

Hoebeke J, Frustaci A, Fenici R. Anti-β-adrenoceptors autoimmunity causing 'idiopathic'

arrhythmias and cardiomyopathy. Circ J. 2012;76(6):1345-53. Epub 2012 Mar 22.

109. Chimenti C, Padua L, Pazzaglia C, Morgante E, Centurion C, Antuzzi D, Russo MA,

Frustaci A. Cardiac and skeletal myopathy in Fabry disease: a clinicopathologic correlative

study. Hum Pathol. 2012 Sep;43(9):1444-52. doi10.1016/j.humpath.2011.09.020. Epub 2012

Mar 8.

110. Frustaci A, Sabbioni E, Fortaner S, Farina M, del Torchio R, Tafani M, Morgante E,

Ciriolo MR, Russo MA, Chimenti C. Selenium- and zinc-deficient cardiomyopathy in

human intestinal malabsorption: preliminary results of selenium/zinc infusion. Eur J Heart

Fail. 2012 Feb;14(2):202-10. doi: 10.1093/eurjhf/hfr167. Epub 2011 Dec 20.

111. . Chimenti C, Frustaci A.Contribution and risks of left ventricular endomyocardial

biopsy in patients with cardiomyopathies: a retrospective study over a 28-year period.

Circulation. 2013 Oct 1;128(14):1531-41. doi: 10.1161/CIRCULATIONAHA.13.001414.

Epub 2013 Sep 4.

112. . Iacucci I, Carbone I, Cannavale G, Conti B, Iampieri I, Rosati R, Sardella G, Frustaci

A, Fedele F, Catalano C, Francone M. Myocardial oedema as the sole marker of acute injury

in Takotsubo cardiomyopathy: a cardiovascular magnetic resonance (CMR) study. Radiol

Med. 2013 May 28. [Epub ahead of print]

15

113. . Galea N, Carbone I, Cannata D, Cannavale G, Conti B, Galea R, Frustaci A, Catalano

C, Francone M. Right ventricular cardiovascular magnetic resonance imaging: normal

anatomy and spectrum of pathological findings. Insights Imaging. 2013 Apr;4(2):213-23.

doi: 10.1007/s13244-013-0222-3. Epub 2013 Feb 8.

114. Frustaci A, Francone M, Petrosillo N, Chimenti C. High prevalence of myocarditis in

patients with hypertensive heart disease and cardiac deterioration. Eur J Heart Fail. 2013

Mar;15(3):284-91. doi: 10.1093/eurjhf/hfs169. Epub 2012 Oct 30.

115. . Frustaci A, Russo MA, Chimenti C Diagnostic contribution of left ventricular

endomyocardial biopsy in patients with clinical phenotype of hypertrophic cardiomyopathy.

Hum Pathol. 2013 Jan;44(1):133-41. doi: 10.1016/j.humpath.2012.04.023. Epub 2012 Aug

30.

116. Francone M; Chimenti C; Galea N, Scopelliti F, Verardo R, Galea R, Carbone I,

Catalano C, Fedele F, Frustaci A .CMR sensitivity varies with clinical presentation and

extent of cell necrosis in biopsy-proven acute myocarditis. J Am Coll Cardiol Img. Published

online February 19, 2014. doi:10.1016/j.jcmg.2013.10.011

PUBBLICAZIONI SU RIVISTE SCIENTIFICHE SENZA IMPACT FACTOR

1. E.Scabbia, F. Bellocci, G. Schiavoni, E. Coppola, B. Domenichelli, A. Frustaci. La terapia

con farmaci vasodilatatori nell'infarto miocardico acuto: contributo casistico. Q.I: Cardiovasc. Ric.

1980; 1:35-48.

2. Frustaci A, Rebuzzi AG, Schiavoni G, Coppola E, Uncini A. Cardiac performance during

hypokalemic rhabdomyolysis. G Ital Cardiol. 1980;10:1570

3. Frustaci A, Gentiloni N, Feoli F Amyloidosis in a mixed pattern. Sensitivity to colchicine

and melphalan. Minerva Medica 1981;72:957-960.

4. Coppola, A. Frustaci, G. Schiavoni, R. Mongiardo, A. Ferrazza. Modificazioni cardiache in

corso di sindrome di Schmidt. Q. I. Cardiovasc. Ric. 1981;2:99-102.

5. Frustaci, U. Manzoli. Soluzioni polarizzanti: utilità e precauzioni. G. Clinica e

Fisiopatologia cardiovascol. 1982;1:189-190.

6. Pennestri F, Mongiardo R, Comparato C, Digaetano A, Mazzari M, Salvatori MP, Frustaci

A, Loperfido F. The electrocardiographic picture of left atrial disorder is not dependent on the form

and entity of atrial enlargement. Bidimensional echocardiographic study. Cardiologia 1982;2:163-

171.

7. Frustaci A, Manzoli U. Methodology, problems and prospectives of endomyocardial

biopsy. Cardiologia 1982;27:1133-1139.

16

8. Mongiardo R, Mazzari M, Schiavoni G, Frustaci A, Lanza G, Pennestrì F. Hemodynamic-

angiographic parameters and histomorphologic biopsy findings in patients with suspected idiopathic

dilated cardiomyopathy. Cardiologia 1982;27:1147-1153.

9. Montenero AS, Frustaci A, Gianolla F, Pennestrì F, Santarelli P, Bellocci F. Clinical,

electrophysiologic and histologic findings in a case of substained idiopathic ventricular tachycardia.

Cardiologia 1982;27:1155-1161.

10. Mongiardo, F. Pennestri, M.P. Salvatori, A. Digaetano, M. Mazzari, A. Frustaci, A.G.

Rebuzzi, A. Ferrazza Diagnosi con Eco 2D di aneurisma del ventricolo sinistro. Clin. Europea

1982; 2: 3-6.

11. Mongiardo, F. Pennestrì, M. P. Salvatori, C. Comparato, M. Mazzari, B. Marino, A.

Digaetano, A. Frustaci. Diagnosi di sede nei versamenti pericardici con ecocardiografia

bidimensionale. Clinica Europea 1982;4:3-8.

12. Mazzari, G. Schiavoni, F. Pennestrì, R. Mongiardo, G. Fiamma, A. Frustaci, A. Digaetano

A, S. Montenero. L'elettrocardiografia dinamica in età pediatrica. Q.I. Cardiovasc. Ric. 1982;3:15-

20

13. Mongiardo, F. Pennestrì, M.P: Salvatori, A. Digaetano, M. Mazzari, A. Frustaci A:S:

Montenero. Aspetti ecocardiografici mono e bidimensionali della mitrale in un caso di

mucopoisaccaridosi tipo II. Q.I. Cardiovasc. Ric. 1982;3:21-27.

14. Montenero, M. Mazzari, R. Mongiardo, A. Frustaci, A. Digaetano, E. Coppola. Ventricolo

destro a doppia uscita : un esempio di connessione ventricolo arteriosa anomala. Embriologia,

anatomia, fisiopatologia, quadri clinico-strumentali, possibilità chirurgiche. Q.I. Cardiovasc. Ric.

1982;3:29-34.

15. Pennestrì, R. Mongiardo, M.P. Salvatori, M. Mazzari, A. Digaetano, A:S: Montenero, A.

Frustaci, G. Schiavoni. Attendibilità dell'Eco 2D nella stima di parametri emodinamici nell'infarto

acuto del miocardio. Q. I. Cardiovasc. Ric. 1982;3:35-41.

16. Mazzari, G. Schiavoni, A. S. Montenero, A. Frustaci, A. Digaetano, R. Mongiardo, F.

Pennestrì. Pseudoaneurisma post-chirurgico del ventricolo sinistro. Descrizione di un caso. Q.I.

Cardiovasc. Ric. 1982;3:43-50.

17. AS Montenero, M. Mazzari, F. Pennestrì, R. Mongiardo, A. Frustaci, B. Domenichelli, M.

Lucente, L.M. Biasucci, et al. L'ECG dinamico nel volo simulato: aspetti fisiopatologici e clinici.

Q.I. Cardiovasc. Ric. 1982;3:51-63.

18. Frustaci, F. Pennestrì, M. Mazzari, R. Mongiardo, A. S. Montenero, A. Digaetano. Danno

miocardico da ipofosfatemia. Q.I. Cardiovasc. Ric. 1982; 3:73-75.

19. Schiavoni G, Mazzari M, Lanza GA, Frustaci A, Mongiardo R, Pennestrì F. Evaluation of

the efficacy and the length of action of a new preparation of slow-release nitroglycerin for

percutaneous absorption (Nitro-Dur, Sigma-Tau) in angina pectoris caused by exercise. Int. J. Clin.

Pharm. Res. 1982; Suppl.1,2.15-20.

17

20. Frustaci, N. Gentiloni, G. Coiana, F. Breccia Ectopic calcifications in adult

hypophosphatasia. Minerva Medica 1983;74:1651-1654.

21. Dei Cas L, Biasucci LM, Buia E, Frustaci A, Manca C, Metra M, Rebuzzi AG. Circadian

aspects of the heart rate in atrial fibrillation patients: the comparative effect of digoxin and

pentaformylgitoxin. Cardiologia. 1983;28:1019-25.

22. Sabatelli M, Casali C, Scoppetta C, Frustaci A, Tonali P. Familial amyloid polyneuropathy.

Description of 2 cases treated with dimethylsulfoxide. Riv Neurobiol. 1984;30:261-7.

23. Mazzari M, Montenero AS, Frustaci A, Lucente M, Mongiardo R, Rebuzzi AG. Late

ventricular arrhythmias in myocardial infarct. Relations with angiographic data. Cardiologia.

1984;29:353-8.

24. Frustaci A, Schiavoni G, Pennestrì F, Ferri T, Lippa S, Oradei A, Littarru G, Manzoli U.

Coenzyme Q10 in dilated cardiomyopathy: a biochemical approach to the treatment. Preliminary

data. Cardiologia 1985;30:1-4.

25. Schiavoni G, Mazzari M, Mongiardo R, Frustaci A, Rebuzzi AG, Pennestri F, Amico C,

Bosimini E, Albanese S, Manzoli U. Nitroglycerin by transdermal route in chronic congestive heart

failure. Cardiologia. 1985;30:1145-51.

26. Manzoli U, Frustaci A, Mazzari M. Dilated Cardiomyopathy. Endomyocardial biopsy.

Cardiologia 1985;30:895-899.

27. Frustaci A, Caldarulo M, Schiavoni G, Coppola E, Bellocci F, Manzoli U. Ventricular

endomyocardial biopsy in "primary" atrial fibrillation. Cardiologia 1986;31:385-388.

28. Frustaci A, Manzoli U. Endomyocardial biopsy of the right ventricle. Cardiologia

1986;31:1001-1005.

29. Frustaci A, Bellocci F, Santarelli P, Manzoli U. Endomyocardial biopsy findings in young

patients with non-sustained ventricular tachycardia and apparently normal heart. In "New trends in

Arrhythmias"; Vol I 1986 pag. 483-486.

30. Manzoli U, Schiavoni G, Frustaci A. Usefulness and limitations of endomyocardial biopsy.

Cardiologia. 1987;32:1483-6.

31. Frustaci, M. Caldarulo, et al. Hypertrophic cardiomyopathy mimicking athlete heart. Risk

of progression and opportunity for a bioptical approach. Cardiologia 1989;34:93-5.

32. Baruffi, S. Bartoccioni, A. Frustaci, et al. Persistenza di ipereosinofilia ed attività

miocardica nella fase fibrotica della malattia endomiocardica. Implicazioni medico chirurgiche.

Archivio di Chir. Toracica e Cardiovascolare Vol. XI 1989;5.

33. Abdulla, A. Frustaci, et al. Congenital lymphangiectasia of interventricular septum.

Cardiologia 35:433-434,1990.

18

34. Frustaci A, Abdulla AK, Caldarulo M, Buffon A. Fatal measles myocarditis. Cardiologia

1990;35:347-349.

35. Abdulla AK, Frustaci A, Amorim D, Olsen EGJ. Assessment of neuron in congenital heart

disease with heart failure. Am Journal of Cardiovascular Pathology 1990;3:265-270.

36. Mori R, Corvaglia AG, Frustaci A. An unusual chronic microvasculitis: Goodpasture's

syndrome with late myocardial involvement. Recenti Prog Med. 1992;83:649-51.

37. Manna R, Liang L, De Santis A, Luchetti R, Antico L, Cristiano G, Frustaci A, Gambassi

G. DR4 HLA Association in the dilated cardiomyopathy. Eur J Int Med 1992;2:213-216.

38. Santarelli P, Frustaci A, Sgadari A, Di Gennaro M, Alessandrini F, Montenero AS, Natale

A, Pisanò E, Biscione F, Carbonin PU, Possati GF. Comparison of atrial electrophysiologic,

histologic and mechanical characteristics in patients with and without atrial fibrillation associated

with the Wolff-Parkinson White syndrome. New trends in arrhythmias-X International Congress

January 1992 pag 289-294.

39. Frustaci A, CaldaruloM, et al.Cardiac biopsy in patients with "primary" atrial fibrillation.

Histologic evidence of occult myocardial diseases. New trends in arrhythmias-X International

Congress January 1992 pag. 732-752.

40. Zeppilli P, Corsetti R, Santini C, Merlino B, Palmieri V, Cameli S, Vannicelli R, La Rosa

Gangi M, Giordano A, Frustaci A, Bellocci F. Differentiation between arrhythmogenic right

ventricular cardiomyophathy and athlete's heart. New trends in arrhythmias X international

Congress January 1992 pag.165-169.

41. MaseriA, Frustaci A. Le infezioni cardiache. Il punto di vista del cardiologo. Giornale di

malattie infettive e parassitarie 1993; 45: 551-555.

42. Santini C, Dello Russo A, Palmieri V, Vannicelli R, Cameli s, Caretta F, Frustaci A,

Zeppilli P. Middle term follow-up in athletes with arrhythmias due to myocarditis. The New

Frontiers of Arrhythmias XII International congress Marilleva 1996; pag 35-42.

43. De Santis A, Fenici R, Frustaci A, Romito A, Manna R. Recurrent Perimyocarditis

Following a non penetrating Chest Trauma. A Case Report. Giornale Italiano Cardiologia 1996;26:

57-60.

44. C Chimenti, A. Frustaci, M Pieroni, A Maseri. Histologically proven myocarditis in patients

with biventricular dysfunction and severe asymptomatic coronary artery disease. Cardiologia

1999;44:177-180.

45. C Chimenti, R Ricci, M Pieroni, L Natale and A Frustaci. Cardiac variant of Fabry's disease

mimiking a hypertrophic cardiomyopathy. Cardiologia 1999, 44:469-473.

46. Chimenti C, Pieroni M, Frustaci A. Celiac disease in idiopathic dilated cardiomyopathy. Ital

Heart J. 2001;2:658-9.

19

47. Chimenti C, Pieroni M, Frustaci A. Celiac disease in idiopathic dilated cardiomyopathy:

reply of the authors. Ital Heart J. 2001;2:658-9.

48. Chimenti C, Frustaci A. Histopathology of myocarditis. Review. Diagnostic Histopathology

2008;14:401-407.

20

COMUNICAZIONI IN CONGRESSI INTERNAZIONALI

1. Rebuzzi, M. Formichi, C. Patrono, E. Scabbia, A. Frustaci, G. Schiavoni. Primary

pulmonary hypertension: effects of hydralazine, indomethacin and isoproterenol Comunicazione IX

Congresso Mondiale Cardiologia, Mosca 1982.

2. Sandric, P. Santarelli, G. Ghirlanda, L. Uccioli, F. Bellocci, A. Frustaci, A.Greco, U.

Manzoli Electrophysiologic effects of Somatostatin in man. Circulation 1984; n4, vol.70, Part II

(Abstract).

3. Frustaci A., Manzoli U., Lippa S., Oradei A., Littarru G. P., and Folkers K. Blood and

intramyocardial levels of Ubiquinone in dilated cardiomyopathy, a biochemical approach to Co Q10

therapy. 5th International Symposium on Coenzyme Q. Tokio 24-26 october 1985.

4. Frustaci, M. Caldarulo, F. Bellocci, G. Schiavoni, U. Manzoli. Endomyocardial biopsy

findings in young patients with ventricular tachycardia and apparently normal heart. 6th European

Congress on Diseases of the Chest.Tel Aviv, Israel, June 15-19, 1986.

5. Gaetano A. Lanza, Antonio G. Rebuzzi, Michele Lucente, Antonio Spagnolo, Andrea

Frustaci, Elda Coppola, Ugo Manzoli. Ventricular arrhythmias in idiopathic dilated

cardiomyopathy. Abstract for World Congress of Cardiology.Washington 14-16 september 1986.

6. Andrea Frustaci. Ruolo della biopsia endomiocardica nelle cardiomiopatie.

Esemplificazioni anatomo-cliiche. International Academy of Pathology, Abano Terme 4-5 ottobre

1986

7. Antonio Nobile, Andrea Frustaci, Federico Giannolla, Marina Caldarulo, Gerardo

Ansalone, Sandro Montenero, Enrico Scabbia, Fulvio Bellocci. Ventricular tachycardia in patients

with "idiopathic" mitral valve prolapse: histologic demostration of associated primary myocardial

abnormalities. JACC abstract 36th Annual Scientific Session American College of Cardiology; New

Orleans, march 8-12 1987.

8. Federico Giannolla, Andrea Frustaci, Antonio Nobile, Gerardo Ansalone, Marina

Caldarulo, Sandro Montenero, Fulvio Bellocci. Apparently idiopathic sustained ventricular

tachycardia responsive to metoprolol in young patients: histologic evidence of silent

cardiomyopathy. JACC abstract 36th Annual Scientific Session American College of Cardiology;

New Orleans march 8-12 1987.

9. Frustaci, A. Nobile, G. Ansalone, M. Caldarulo, S. Montenero, F. Bellocci. Apparently

idiopathic sustained ventricular tachycardia responsive to metoprolol in young patients: histologic

evidence of silent cardiomyopathy. PACE 1987;10:985.

10. Frustaci, A. Nobile, G. Ansalone, M. Caldarulo, S. Montenero, F. Bellocci. Ventricular

tachycardia in patients with "idiopathic" mitral valve prolapse: histologic evidence of associated

primary myocardial abnormalities. PACE 1987;10:986.

11. Frustaci, M. Caldarulo, F. Bellocci, M.A. Russo, U. Manzoli, A. Cittadini. Myocardial

magnesium content in primary ventricular tachycardia. Relation between myocardial Mg, histology

21

and antiarrhythmic response to Mg infusion. The new frontiers of arrhythmias Marilleva january 31-

february 6;1988

12. Bellocci, A. Frustaci, A. Nobile, M. Caldarulo, A. Spampinato, S. Montenero. Apparently

idiopathic sustained ventricular tachycardia responsive to metoprolol in young patients: histologic

evidence of silent cardiomyopathy. European Heart J. october 1987.

13. Ansalone, A. Frustaci, A. Nobile, V. Affinito, M. Caldarulo, S. Montenero, F. Bellocci.

Apparently idiopathic sustained ventricular tachycardia responsive to metoprolol in young patients:

histologic evidence of silent cardiomyopathy. Latido 1987;12:32.

14. A.Nobile, A. Frustaci, V. Affinito, M. Caldarulo, G. Ansalone, S. Montenero, E. Scabbia,

F. Bellocci. Ventricular tachycardia in patients with ""idiopathic" mitral valve prolapse: histologic

demostration of associated primary myocardial abnormalities. Latido 1987;12:33.

15. Abdulla, A. Frustaci, et al. Congenital limphangectasia of the right ventricle. Angiology

1988 (Abstract 35th Cong. of American College of Angiol.).

16. Frustaci, M. Caldarulo, et al. Cardiac involvement in systemic sclerosis immune-histologic

study and clinical correlation.CHEST August 1988.

17. Frustaci, M. Caldarulo, et al. Adriamycin myocardiotoxicity: an ultrastructural study and a

pathogenetic hypotesis.CHEST August 1988.

18. Frustaci, M. Caldarulo, et al. Increased myocardial mastcells and histamine release in

ventricular arrhythmias due to myocarditis; antiarrhythmic effect of H2-antihistamines. CHEST

August 1989 (abstract ACCP Congress)

19. Frustaci, M. Caldarulo, et al. Adriamycin myocardiotoxicity: an ultrastructural study and a

pathogenetic hypothesis. International Congress of Cardiomyopathies- Florence 1989

20. Frustaci, M. Caldarulo, et al. Cardiac involvement in systemic sclerosis immune-histologic

study and clinical corralation. International Congress on Cardiomyopathies- Florence 1989

21. Frustaci, M. Caldarulo, et al. Cardiac biopsy findings in "primary" atrial fibrillation:

Histologic evidence of occult myocardial disease. World Congress of Cardiology- Manila 1990

(accepted for oral comm.)

22. F Belloci, S. Montenero, A. Nobile, G. Ansalone, A. Frustaci, U. Manzoli. Oral flecainide

for prevention of paroxismal atrial fibrillation: Predictive value of the response to transesophageal

atrial stimulation. JACC (oral presentation at 39th Annual Scientific Session-New Orleans March

1990)

23. Frustaci, M. Caldarulo, A. Buffon, M. Testa. Small vessel disease as a cause of stable

angina. Biochemical and histologic evidence. XI World Congress of Cardiology- Manila Feb 1990.

24. Frustaci, M. Caldarulo, A. Buffon, F. Bellocci, U. Manzoli Cardiac biopsy findings in

"primary" atrial fibrillation: histologic evidence of occult myocardial disease. XI World Congress of

Cardiology-Manila Feb 1990.

22

25. Frustaci, et al. HLA association in the dilated cardiomyopathy.XI World Congress of

Cardiology-Manila Feb 1990.

26. Bellocci, S. Montenero, A. Nobile, G. Ansalone, A.Frustaci, U. Manzoli. Oral flecainide for

prevention of paroxismal atrial fibrillation: predictive value of the response to transesophageal atrial

stimulation. JACC Vol 15, No 2 Feb 1990:235A

27. Frustaci, et al. Cardiac biopsy findings in "primary" atrial fibrillation: histologic evidence

of occult myocardial disease. Cardiostim 90-Nizza 20-23 Giu 1990.

28. Pragliola, A. Frustaci, et al. Hemodynamic behavior and correlations with myocardial

lesions in an experimental model of brain death. Current issues in Thoracic Organ Trasplantation.

Essen, 19-21 Sept 1991.

29. Melina, F. Colivicchi, G. Melina, A. Frustaci, A. Santoliquido, M. Caldarulo. Silent

myocardial ischemia in asymptomatic diabetic patients with essential hypertension. European Heart

J - supplement August 1991.

30. Melina, A. Frustaci, et al. Silent myocardial ischemia and ventricular arrhythmias in

asymptomatic diabetic patients with essential hypertension. III International Symposium

"Hypertension associated with diabetes mellitus". Boston USA November 21-23 1991.

31. Frustaci, M. Caldarulo, N. Magnavita, A. Pietra, E. Sabbioni: Assessment of myocardial

heavy metals content in patients with idiopathic dilated cardiomyopathy. Circulation (abstract)

suppl october 1992.

32. Nobile, A. Frustaci, P. Zeppilli, A. Spampinato, A. Montenero, P. Zecchi, F. Bellocci.

Idiophatic severe ventricular arrhythmias in young patients: ventricular late potentials as initial

manifestation of organic heart disease. Eur Heart J (abstract) Supplement August 1992.

33. Frustaci, C. Cellini, F. Bellocci, A. Maseri. Young Survisors of apparently idiopathic

cardiac arrest : results of bi-ventricular endomyocardial biopsy and specific treatment and meadle

term follow-up. Eur. Heart Journal vol.14 ; abstract supplement : August 1993.

34. Nobile, A. Frustaci, P. Zeppilli, A. Spampinato, S. Montenero, P. Zecchi, F. Bellocci.

Idiophatic severe ventricular arrhythmias in young patients: ventricular late potentials as initial

manifestation of organic heart disease. JACC 1993; 21 :2- (abstract)

35. Frustaci A, Chimenti C, Di Francesco P, Bellocci F, Russo MA. Results of atrial biopsy in

patients with lone atrial fibrillation. XII International Congress “The New Frontiers of Arrhythmias”

Marilleva 1996; 91-94

36. Frustaci A, Chimenti C, Morgante E, Russo MA, Maseri A. The histologic substrate of

atrial biopsy in patients with lone atrial fibrillation. Eur Heart J Supplement August 1996

37. Frustaci A, Chimenti C, Morgante E, Russo MA, Maseri A. The histologic substrate of

atrial biopsy in patients with lone atrial fibrillation. Circulation Supplement November 1996

23

38. Frustaci A, N. Magnavita, C. Chimenti, M. Caldarulo et al. Marked elevation of myocardial

trace elements in idiopathic dilated cardiomyopathy compared to secondary cardiac

dysfunction. 6th

world congress on heart failure mechanisms and management. Geneva May

17-20 1998

39. Frustaci A, N. Magnavita, C. Chimenti, M. Caldarulo et al. Assessment of myocardial

and muscular trace elements in patients with idiopathic dilated cardiomyopathy and

secondary cardiac dysfunction. American Heart Association 71st Scientific session November

8-11 1998

40. Frustaci A, C Chimenti, M Setoguchi, S Corsello, M Pieroni, F Crea, A Leri, J kajstura,

P Anversa, A Maseri. Cell Death in Acromegalic cardiomyopathy J Am Coll Cardiol

1999;33:501 A

41. Frustaci A, C Chimenti, Pieroni M. Prognostic significance of left ventricular aneurysms

with normal global function caused by myocarditis. Eur Heart J Supplement August 1999.

42. Frustaci A, C Chimenti, Jakoniuk I, A Leri, J kajstura, P Anversa, A Maseri. Type-II

non insulin-dependent diabetes mellitus (NIDDM) and cardiac cell death. Circulation 2000;

102: 3040A.

43. Chimenti C, Calabrese F, Thiene G, Pieroni M, Maseri A, Frustaci A. Inflammatory left

ventricular microaneurysms as a cause of apparently idiopathic ventricular tachyarrhythmias.

JACC 2001;37 Suppl A:1106A.

44. Frustaci A, Calabrese F, Chimenti C, Pieroni M, Thiene G, Maseri A. Myocarditis as

lone manifestation of HCV infection: effects of immunosuppressive therapy. Cardiovascular

drugs and Therapy (15) Suppl 1 March 2001.

45. Chimenti C, Calabrese F, Thiene G, Pieroni M, Maseri A, Frustaci A. Inflammatory left

ventricular microaneurysms as a cause of apparently idiopathic ventricular tachyarrhythmias.

Cardiovascular drugs and Therapy (15) Suppl 1 March 2001

46. Chimenti C, Calabrese F, Thiene G, Pieroni M, Maseri A, Frustaci A. Inflammatory left

ventricular microaneurysms as a cause of apparently idiopathic ventricular tachyarrhythmias.

Eur Heart J Supplement August 2001

47. Chimenti C, Pieroni M, Verardo R, Maseri A, Frustaci A. Histologic findings in patients

with clinical and instrumental diagnosis of arrhythmogenic right ventricular dysplasia. JACC

2002;39 Suppl A:135A.

49. Chimenti C, Pieroni M, Cuoco L, Verardo R, Gentiloni Silveri N, Maseri A, Frustaci A.

Celiac disease associated with autoimmune myocarditis. Congress of the European Society of

Cardiology. Berlin, September 2002.

50. Chimenti C, Pieroni M, Calabrese F, Verardo R, Thiene G, Maseri A, Frustaci A. Active

Lymphocytic Myocarditis: Virologic and Immunologic Profile of Responders vs Non-Responders

To Immunosuppressive Therapy. Congress of the European Society of Cardiology. Berlin

September 2002.

24

51. Chimenti C, Pieroni M, Verardo R, Maseri A, Frustaci A. Histologic Findings in Patients

with Clinical and Instrumental Diagnosis of Arrhythmogenic Right Ventricular Dysplasia. Congress

of the European Society of Cardiology. Berlin, September 2002.

52. Pieroni M, Chimenti C, Verardo R, Maseri A, Frustaci A. Brain Natriuretic Peptide in

Hypertrophic Cardiomyopathy with and without Systolic Dysfunction. Congress of the European

Society of Cardiology. Berlin, September 2002.

53. Pieroni M, Chimenti C, Calabrese F, Verardo R, Thiene G, Maseri A, Frustaci A. Lone

HCV Myocarditis Responsive to Immunosuppressive Therapy. Congress of the European Society of

Cardiology. Berlin, September 2002.

54. Chimenti C, Pieroni M, Maseri A, Frustaci A. Histologic findings in patients with clinical

and instrumental diagnosis of sporadic Arrhythmogenic Right Ventricular Dysplasia. Abstract on

American Heart Congress (Circulation 2002).

55. Chimenti C, Kajstura J, Torella D, Urbanek K, Heleniak H, Colussi C, Di Meglio F, Nadal-

Ginard B, Frustaci A, Leri A, Maseri A, Anversa P. Senescence and death of primitive cells and

myocytes leads to premature cardiac aging and heart failure. Abstract on American Heart Congress

(Circulation 2002).

56. Pieroni M, Chimenti C, Ricci R, Russo MA, Sale P, Maseri A, Frustaci A. Early detection

of Fabry cardiomyopathy by tissue Doppler imaging. Congress of the American College of

Cardiology 2003.

57. Nanni L, Pieroni M, Chimenti C, Simionati B, Zimbello R, Maseri A, Frustaci A,

Lanfranchi G. Hypertrophic cardiomyopathy: two homozygous cases with "typical" hypertrophic

cardiomyopathy and three new mutations in cases with progression to dilated cardiomyopathy.

Congress of the European Society of Cardiology. Vienna, September 2003.

58. Pieroni M, Chimenti C, Bellocci F, Sale P, Russo MA, Maseri A, Frustaci A. Biventricular

histologic findings in patients with Brugada syndrome. Congress of the European Society of

Cardiology. Vienna, September 2003.

59. Chimenti C, Pieroni M, Russo A, Verardo R, Russo MA, Maseri A, Frustaci A.

Intramyocyte detection of Epstein Barr virus genome by laser capture microdissection in patients

with inflammatory cardiomyopathy. Congress of the American Heart Association November 2003.

60. Chimenti C, Pieroni M, Antuzzi D, Morgante E, Russo MA, Maseri A, Frustaci A.

Prevalence of Fabry Disease in female patients with hypertrophic cardiomyopathy. Congress of the

American Heart Association November 2003.

61. Pieroni M, Chimenti C, Bellocci F, Sale P, Russo MA, Maseri A, Frustaci A. Biventricular

histologic findings in patients with Brugada syndrome. Congress of the American Heart Association

November 2003.

25

62. Chimenti C, Pieroni M, Maurizio Pieroni, Andreina Santagostino, Matteo A Russo, Attilio

Maseri, Andrea Frustaci. Histologic determinants of diastolic dysfunction in patients with Fabry

cardiomyopathy. Congress of the European Society of Cardiology. Munich, September 2004.

63. Chimenti C, Pieroni M, Russo A, Verardo R, Russo MA, Maseri A, Frustaci A.

Intramyocyte detection of Epstein Barr virus genome by laser capture microdissection in patients

with inflammatory cardiomyopathy. Congress of European Society of Cardiology. Munich,

September 2004.

64. Pieroni M, Chimenti C, Santagostino A, Maseri A, Corti A, Frustaci A. Myocardial

production and secretion of chromogranin A in hypertrophic cardiomyopathy. 1st biannual meeting

of the Association for European Cardiovascular Pathology. October 21-23, 2004. Padua.

65. Chimenti C, Pieroni M, Santagostino A, Russo MA, Maseri A, Frustaci A. Histologic

determinants of diastolic dysfunction in patients with Fabry cardiomyopathy.. 1st biannual meeting

of the Association for European Cardiovascular Pathology. October 21-23, 2004. Padua.

66. Pieroni M, Chimenti C, Santagostino A, Maseri A, Corti A, Frustaci A. Myocardial

production and secretion of chromogranin A in hypertrophic cardiomyopathy. Congress of the

American Heart Association New Orleans, Louisiana, November 2004

67. Pieroni M, Chimenti C, Santagostino A, Maseri A, Corti A, Frustaci A. Myocardial

production and secretion of chromogranin A in hypertrophic cardiomyopathy. Congress of

European Society of Cardiology, Stockolm, Sweden, September 2005

68. Pieroni M, Chimenti C, Verardo R, Maseri A, Frustaci A. Brain Natriuretic Peptide in

Hypertrophic Cardiomyopathy with and without Systolic Dysfunction. Congress of European

Society of Cardiology, Stockolm, Sweden, September 2005

69. Pieroni M , Chimenti C, Nanni L, Belloni E, Lanfranchi G, Frustaci A. Gene expression

profiling in Fabry cardiomyopathy. Dallas, Texas, November 2005

70. Chimenti C, Pieroni M, Verardo R, Frustaci A. Prevalence of myocardial viral infection in

patients with cardiac syndrome X. Dallas, Texas, November 2005

71. Chimenti C, Pieroni M, Salvatori L, Morgante E, Sale P, Petrangeli E, Gulino R, MA Russo,

Frustaci A. Cellular mechanisms of cardiac recovery in patients with inflammatory cardiomyopathy

responding to immunosuppressive therapy. Dallas, Texas, November 2005.

72. Chimenti C, Hamdani N, Pieroni M, van der Velden J, Stienen GJM, Gaudio C, Paulus WJ,

Frustaci A. Alterations in Myocyte Relaxation and Contraction are the Main Mechanisms of

Cardiac Dysfunction in Fabry Cardiomyopathy. European Congress on Heart Failure, Helsinki,

Finland, July 2006

73. Chimenti C, Verardo R, Caldarulo M, Russo MA, Frustaci A. Myocarditis in hypertrophic

cardiomyopathy patients presenting acute clinical deterioration. European Congress of Cardiology,

Barcelona, Spain, September 2006.

26

74. Chimenti C, van der Velden J, Hamdani N, Stienen GJM, Russo MA, Paulus WJ, Frustaci

A, Myofilament Dysfunction in Human Cardiomyocytes with Fabry Disease. American Heart

Association Congress, Chicago, Illinois 2006.

75. Chimenti C, Tanzilli G, Morgante E, Verardo R, Mangieri E, Gaudio C, Russo MA,

Frustaci A. Fabry‟s Disease: Coronary Small Vessel Obstruction as a Cause of Myocardial

Ischemia and Disease Progression. American Heart Association Congress, Chicago, Illinois 2006.

76. Chimenti C, Verardo R, Acconcia MC, Caldarulo

M, Russo

MA, Frustaci

A. Myocarditis in

hypertrophic cardiomyopathy patients presenting acute clinical deterioration. Heart Failure

Congress 2007 Hamburg, Germany. Accepted

77. Chimenti C, Verardo R, Sale P, Russo MA, Frustaci A. Viral infection of intramural

coronary vessels in patients with cardiac Syndrome X. European Congress of Cardiology, Munich,

Germany, September 2008, submitted.

78. Chimenti C, Morgante E, Tanzilli G, Verardo R, Manieri E, Gaudio C, Russo MA, Frustaci

A. Fabry‟s Disease: Coronary Small Vessel Obstruction as a Cause of Myocardial Ischemia and

Disease Progression. European Congress of Cardiology, Munich, Germany, September 2008,

submitted.

27

COMUNICAZIONI IN CONGRESSI NAZIONALI

1. Frustaci A, Carbone A, Pennestrì F, Mongiardo R, De Santis F, Loperfido F, Coppola E.

Disordine immunitario in corso di fibrosi endomiocardica.Comunicazione Congresso Soc. Ital.

Cardiol. 1982.

2. Pennestrì F, Mongiardo R, Salvatori MP, Comparato C, Digaetano A, Mazzari M, Frustaci A,

Loperfido F. Analisi quantitativa con Eco 2D dell'interessamento calcifico del lembo anteriore in

rapporto alla gravità della stenosi mitralica. Comunicazione XLIII Congr. Soc. Ital. Cardiol. 1982.

3. Maini CL, Schiavoni G, Montenero AS, Soricelli A, Frustaci A, Bonetti M, Mazzari M.

Determinazione non geometrica dei volumi telediastolico e telesistolico in angiocardioscintigrafia.

Comunicazione XLIII Congr. Soc. Ital. Cardiol. 1982.

4. Rebuzzi AG, Schiavoni G, Scabbia E, Frustaci A, Mongiardo R, Spagnolo A. Ipertensione

polmonare primitiva: effetti dell'idralazina, isoproterenolo, nofedipina, fentolamina. Comunicazione

XLIII Congr. Soc. Ital. Cardiol. 1982.

5. Frustaci A, Pennestri F, Mazzari M, Rebuzzi AG, Coppola E, Bellocci F. Cardiomiocitolisi

ipokaliemica. Comunicazione XLIII Congr. Soc. Ital..Cardiol. 1982.

6. Maini CL, Montenero AS, Soricelli A, Frustaci A, Ficola U, Turbati M. Studio della

funzionalità sistilica e della funzionalità diastolica del ventricolo sinistro mediante nuclear

stethoscope. Comunicazione XLIII Congr. Soc.. Ital. Cardiol. 1982

7. Montenero AS, Frustaci A, Mongiardo R, Pennestri F, Turbati M, Marino B, Coppola E.

Sindrome asplenica e polisplenica dell'adulto. Comunicazione XLLL Congr. Soc. Ital. Cardiol. 1982

8. Frustaci A, Bellocci F, Rebuzzi AG, Montenero AS, De Santis F, Dulcimascolo C.

Modificazioni metaboliche cardiache in corso di paralisi ipokaliemica periodica familiare.

Comunicazione XLIV Congr. Soc. Ital. Cardiol. 1983.

9. Montenero AS, Sandric S, Gianolla F, Pavone G, Frustaci A, Comparato C, Turbati M,

Bellocci F. Effetti emodinamici e antiaritmici della mexiletina nella fase acuta dell'infarto

miocardico. Comunicazione XLIV Congr. Soc. Ital. Cardiol. 1983.

10. Biasucci LM, Rebuzzi AG, Mazzari M, Frustaci A, Amico C, Dulcimascolo C, Bosimini E.

Ruolo della frequenza cardiaca nella genesi degli episodi di ischemia miocardica. Comunicazione

XLIV Congr. Soc. Ital. Cardiol. 1983.

11. Frustaci A, Bellocci F, Mazzari M, Rebuzzi AG, Amico CM, Duricchi M. Efficacia dei

betabloccanti nel trattamento delle aritmie ventricolari e sopraventricolari in corso di cardiomiopatia

dilatativa iniziale. Atti XLV Congresso Nazionale della Società Italiana di Cardiologia 1984.

12. Frustaci A, Coppola E, Ferri T, Martuscelli E, Mangeri E, Nigri A. Evoluzione e prognosi della

cardiomiopatia dilatativa: follow-up a tre anni. Comunicazione al XLVI Congresso Nazionale della

Società Italiana di Cardiologia 10-14 Dicembre 1985.

28

13. Frustaci A, Littarru G, Schiavoni G, Pennestrì F, Lucente M, Mazzari M, Rossi E, Ferri T.

Determinazione plasmatica e intramiocardica del Coenzima Q 10 nella cardiomiopatia dilatativa.

Effetti sul ritmo e la contrattilità dopo somministrazione orale. Comunicazione al XLVI Congresso

Nazionale della Società Italiana di Cardiologia dicembre 1985.

14. Frustaci A, Caldarulo M, Rossi E, Coppola E, Manzoli U. Miocardite virale. Valutazione

clinico-istologica al trattamento steroideo ed immunosoppressivo. Comunicazione al XLVII

Congresso Nazionale della Società Italiana di Cardiologia Roma 16-20 dicembre 1986.

15. Frustaci A, Manzoli U. Biopsia endomiocardica del ventricolo dx. Relazione al Simposio su "Il

Ventricolo destro", XLVII Congresso Nazionale della Società italiana di Cardiologia; Roma 16-20

dicembre 1986

16. Mazzari M, Frustaci A, Biasucci LM, Littarru GP, Manzoli U. Il Coenzima Q10 nella

cardiopatia ischemcia. Dati preliminari. Gruppo di studio " Cardiologia Sperimentale" Gardone

Riviera 16-18 aprile 1986.

17. Servidei S, Frustaci A, Sabatelli M, Ricci E, Restuccia D, Di Mauro S, Tonali P.Myopathy and

cardiomyopathy with Glycogen: morphological and biochemical studies of an unusual case. Atti

Congresso Società Nazionale di Neuropatologia. Journal Neurol Sci, luglio 1987.

18. Manzoli U, Schiavoni G, Frustaci A. Utilità e limiti della biopsia endomiocardica nel

laboratorio di emodinamica. Relazione al XLVIII Congresso Nazionale della Società Italiana di

Cardiologia; dicembre 15-19 1987.

19. Greco G, Arcari L, Vegna ML, Frustaci A. Cardiotossicità da antraciclina: decorso e

reversibilità clinica Comunicazione al XLVIII Congresso Nazionale della Società Italiana di

Cardiologia; dicembre 15-19 1987.

20. Frustaci A, Manzoli U. Il microcircolo nelle malattie del muscolo cardiaco. Congresso

Nazionale sul Microcircolo; Fano 1988.

21. Frustaci A. Dispasia adiposa del ventricolo destro. Diagnosi differenziale con le cardiomiopatie

primitive di tipo dilatativo. Relazione al XLIX Congr. Nazionale Soc. Ital. Cardiol. Dic. 1988

22. Frustaci, Caldarulo M, Buffon A, Trani C, Gentiloni N. Patterns istomorfologici inusuali di

amiloidosi cardiaca. Giornate Cardiologiche Romane- Roma 19-2 Apr 1990

23. Zeppilli P., Frustaci A., Merlino B., Bellocci F. Aritmie ventricolari e miocardite in atleti:

un'associazione da non dimenticare. Congresso Nazionale Medicina dello Sport - Roma 1991.

24. Santarelli P, Frustaci A, Sgadari A, Di Gennaro M, Alessandrini F, Natale A, Pisanò E,

Biscione F, Carbonin PU, Possati GF. Caratteristiche istologiche e proprietà meccaniche del tessuto

atriale in pazienti con sindrome di Wolff- Parkinson- White. Cardiologia - vol.36 suppl 2 al n12 -

Dicembre 1991.

25. Melina S, Frustaci A, et al. Ipertensione arteriosa e infarto del miocardio nell'anziano diabetico.

XCII Congresso Nazionale della Società Italiana di Medicina Interna. Roma 15-19 Ottobre 1991.

29

26. Melina S, Frustaci A, et al. Modificazioni della pressione arteriosa e dei tempi sistolici del

ventricolo sinistro dopo sforzo isometrico in figli di ipertesi con e senza diabete mellito XCII

Congresso Nazionale della Società Italiana di Medicina Interna. Roma 15-19 Ottobre 1991.

27. Frustaci A. Relazione "Cardiomiopatia dilatativa reversibile da carenza di GH" Congresso

Internazionale "GH oggi:non solo crescita" Roma 31 Gen - 1 Feb 1992.

28. Frustaci A., Chimenti C., Bellocci F., Morgante E., Russo M.A., Maseri A. Biopsia miocardica

atriale in pazienti con fibrillazione atriale isolata. Congresso Nazionale della Associazione Medici

Cardiologi Ospedalieri 1997

29. Frustaci A., Chimenti C., Bellocci F., Morgante E., Russo M.A., Maseri A. Biopsia miocardica

atriale in pazienti con fibrillazione atriale isolata. LVII Congresso Nazionale della Società Italiana

di Cardiologia 1996

30. Chimenti C., Frustaci A., Pieroni M., Maseri A. Una disfunzione cardiaca biventricolare in

pazienti con coronaropatia asintomatica puo‟ essere causata da una miocardite piuttosto che

da ischemia miocardica. LIX Congresso Nazionale della Società Italiana di Cardiologia 1998

31. Chimenti C, Pieroni M, Bellocci F, Frustaci A. Aneurismi infiammatori localizzati del

ventricolo sinistro come causa di aritmie ventricolari a cuore apparentemente sano. LXI

Congresso Nazionale della Società Italiana di Cardiologia 2000

32. Chimenti C, Pieroni M, Calabrese F, Thiene G, Maseri A, Frustaci A. Miocardite come

unica manifestazione di infezione da hcv sensibile al trattamento immunosoppressivo LXII

Congresso Nazionale della Società Italiana di Cardiologia 2001.

33. Pieroni M, Chimenti C, Maseri A, Frustaci A. Correlazione tra livelli plasmatici di brain

natriuretic peptide e fase dilatativa nella cardiomiopatia ipertrofica. LXII Congresso

Nazionale della Società Italiana di Cardiologia 2001.

34. Pieroni M, Chimenti C, Ricci R, Sale P, Russo MA, Maseri A, Frustaci A. Diagnosi precoce

di coinvolgimento cardiaco nella malattia di Fabry attraverso il Doppler tissutale. LXIII

Congresso Nazionale della Società Italiana di Cardiologia 2002.

35. Pieroni M, Chimenti C, Bellocci F, Sale P, Russo MA, Maseri A, Frustaci A. Biventricular

histologic findings in patients with Brugada syndrome. LXIV Congresso Nazionale della

Società Italiana di Cardiologia 2003.

36. Pieroni M, Chimenti C, Santagostino A, Maseri A, Corti A, Frustaci A. Myocardial

production and secretion of chromogranin A in hypertrophic cardiomyopathy. LXV

Congresso Nazionale della Società Italiana di Cardiologia 2004

37. Chimenti C, Pieroni M, Santagostino A, Verardo R, Maseri A, Frustaci A. Histologic

Findings in Patients with Clinical and Instrumental Diagnosis of Arrhythmogenic Right

Ventricular Dysplasia. LXV Congresso Nazionale della Società Italiana di Cardiologia 2004.

30

CAPITOLI IN LIBRI

1. Frustaci A, Manzoli U, Lippa S, Oradei A, Littarru GP and Folkers K. Blood and myocardial

levels of Ubiquinone in dilated cardiomyopathy: a biochemical approach to Co Q 10 therapy.

In: "Biomedical and clinical aspects of coenzime Q"; K. Folkers and Y. Yamamura Editors.

Elsevier publisher 1986 pag.157-164.

2. Frustaci A, Bellocci F, Manzoli U. Usefulness of endomyocardial biopsy in brady and

tachyarrhythmias. Etiopathogenetic definition.

In: "Progress in Clinical Pacing" edited by M. Santini , M. Pistolese, A. Alliegro, Rome 1986 pg

187-191.

3. Fenici RR, Ruggieri MP, Frustaci A. Le indagini invasive in cardiologia dello sport: nozioni

generali e loro utilità.

In: Cardiologia dello Sport (Paolo Zeppilli) 1995.

4. Zeppilli P, Santini C, Frustaci A. Cardiomiopatie, miocarditi e pericarditi in cardiologia dello

sport.

In: Cardiologia dello Sport (Paolo Zeppilli) 1995.

5. Frustaci A, Chimenti C, Zeppilli P. Terapia nelle malattie del sistema cardiovascolare.

In: Terapia medico-chirurgica. D. Gui, M Azzaretto. 2000 pag 193-262.

In fede

ANDREA FRUSTACI