Kiran Kumar Thumburu Address: #3424, D-Block, Advanced Pediatric Centre, PGIMER, Chandigarh

Mobile: +91-9417745337 ~ E-Mail: kiranpgi@gmail.com

Seeking challenging assignments in the area of Clinical Research & Development / Bio-statistics / Systematic Reviews/Critical appraisal/Medical Writing / Clinical Data analyst &

Management with an organisation of repute

Preferred Location – Bangalore / Chennai / Hyderabad / Pune

CAREER OVERVIEW

Ph.D. (Medical) with nearly 4.5 years of insightful experience in managing the Clinical Research & Development and

enhancing the process operations. Currently associated with ICMR Advanced Centre for Evidence Based Child

Health, Postgraduate Institute of Medical Education and Research (PGIMER), Chandigarh, India as Senior Research

Officer (Scientist C). Acquired comprehensive exposure in planning and organizing day-to-day Clinical Research

activities and executing tasks as appropriate to the timely accomplishment of research objectives. Skilled in medical

writing and publishing original manuscripts, systematic reviews, writing research grants and proposals, manuscript

reviewing, editing cochrane reviews, management and supervision of ongoing projects (ICMR & WHO Project). Adept

at organising Capacity Building Workshops on “How to Teach and How to Practice Evidence Based Medicine” to

Clinicians, Residents, Researchers, Microbiologists, Librarians and Nurses. Functioned as Visiting Scholar at

Neuroscience Research Unit, Saint-Luc Hospital (CHUM), Montreal, Canada (Mentor: Prof Roger Butterworth’s). An

energetic, self-motivated team leader with hands-on experience in requirements gathering, examination, evaluation &

customization.

EMPLOYMENT RECITAL

Since 2012: ICMR Advanced Centre for Evidence Based Child Health, Postgraduate Institute of Medical Education and Research (PGIMER), Chandigarh, India as Senior Research Officer (Scientist C)

2005 – 2012: Postgraduate Institute of Medical Education and Research (PGIMER). Chandigarh, India as Senior

Research Fellow (Ph.D)

Research Advisor: Radha K Dhiman, Department of Hepatology

2003 – 2005: Kamineni Institute of Medical Sciences, Hyderabad, Andhra Pradesh, India as Lecturer / Tutor in Biochemistry

Key Deliverables

Identifying, collecting, processing, analysing and cataloguing data according to established protocol, procedures & standards, as appropriate to specific objectives of the research study.

Gained expertise in Bio-statistics, Systematic Reviews, Meta-analysis, Network Meta-Analysis, clinical data analysis, Health Technology Assessment, Literature Search, Clinical Research, Medical Writing, Methodological Teaching, Critical Appraisal, Clinical Trials and Policy Briefs.

Acquired knowledge of Statistical software like SPSS, STATA, RevMan (Meta-Analysis), Epi Info and GraphPad Prism as well as conversant with all statistical analysis such as Logistic Regression, Linear Regression, Survival Analysis, KM Analysis, Odds Ratio, Meta-Analysis, Network Meta-Analysis, etc.

Designing of various experiments for the study, documentation of data, data management, literature updates and report presentations.

Maintaining a broad knowledge of state-of-the-art research techniques, technology and the systems.

Inspecting standards and taking the necessary actions for the non conformities.

SKILL SET

Clinical Research & Development Systematic Reviews & Meta-analysis Medical Writing

Clinical Data Analysis & Management Health Technology Assessment Clinical Trials

Critical Appraisal Literature Search Bio-statistics

HONORS /AWARDS

INASL-ABBOT Presidential Poster Award, 2016 at 24th Annual Scientific Meeting of Indian National Association for Study of the Liver (INASL), Gurgaon, Delhi (NCR) (5th – 7th Aug’16)

Major General Amir Chand Gold Medal for the year 2013 by PGIMER, Chandigarh

Young Investigator Award at 15th International Society on Hepatic Encephalopathy and Nitrogen Metabolism (ISHEN), 2012 at Grenaa, Denmark

Best Presentation Award (Plenary) at “53rd Annual Conference of Indian Society of Gastroenterology (ISGCON)” held at Jaipur, India from 28th Nov’12– 1st Dec’12

Best Presentation Award and Travel Award at “Seoul International Digestive Disease Symposium (SIDDS-2012)” held at Seoul, South Korea from 22nd – 23rd November, 2012

International Travel Award from Indian Council of Medical Research (ICMR) to attend 15th ISHEN, 2012 at Grenaa, Denmark

Best Presentation Award (Oral) at 52nd ISGCON, 2011 at Coimbatore, India

Best Presentation Award (oral) at 51st ISGCON, 2010 at Hyderabad, India

Student Award at 14th ISHEN, 2010 at Val David, Canada

International Travel Award from Council of Scientific and Industrial Research (CSIR) to attend 14th ISHEN, 2010 at Val David, Canada

SCHOLASTICS

Ph.D. (Medical) from Postgraduate Institute of Medical Education & Research (PGIMER), Chandigarh in 2012

M.Sc. (Biochemistry Medical) from Manipal University, Manipal in 2003

PROFESSIONAL MEMBERSHIPS

Life Member of the International Society on Hepatic Encephalopathy and Nitrogen Metabolism (ISHEN)

Life Member of the Indian Immunological Society (IIS)

PUBLICATIONS & RESEARCH WORKS

Successfully Published:

18 Research Paper/Indexed Journals and 5 are under publication

1 Research Papers/ Non-indexed Journals

20 Abstracts/Indexed Journals

2 Book Chapters

1 Book Editor

2 (Protocols) Cochrane Reviews and 1 (Protocol) is under publication

Attended 25 Workshops as Faculty and 7 as Participant IT Skills: Comprehensive exposure to the latest version of Microsoft Windows and Microsoft Office, Microsoft Excel, Microsoft PowerPoint, Basic Knowledge of various software of Nucleotide Sequence Analysis, Restriction Mapping, Nucleic Acid Sequence

Data Bank, Primer Designing & BLAST Search

PROFESSIONAL ENHANCEMENTS

Publications: Thumburu KK, Dhiman RK, Vasishta RK, Chakraborti A, Beauchesne E, Desjardins P, Butterworth RF, Goyal S, Ajay

Duseja, Yogesh Chawla and Navneet Sharma. Expression of astrocytic genes coding for proteins implicated in neural excitation and brain edema is altered after acute liver failure. J Neurochem. 2014 Mar; 128(5):617-27.

Dhiman RK, Rana B, Agrawal S, Garg A, Chopra M, Thumburu KK, Khatri A, Malhotra S, Duseja A, Chawla YK. Probiotic VSL#3 Reduces Liver Disease Severity and Hospitalization in Patients with Cirrhosis: a Randomized, Controlled Trial. Gastroenterology 2014 Dec;147(6):1327-1337

Thumburu KK, Dhiman RK, Vasishta RK, Chakraborti A, Beauchesne E, Desjardins P, Butterworth RF, Ajay Duseja, Yogesh Chawla and Navneet Sharma. Role of Glial Fibrillary Acid Protein and Aquaporin-4 in the Development of Cerebral Edema in Type C Hepatic Encephalopathy (Communicated in Glia)

Samanta J, Dhiman RK, Khatri A, Thumburu KK, Grover S, Duseja A, Chawla Y. Correlation between degree and quality of sleep disturbance and the level of neuropsychiatric impairment in patients with liver cirrhosis. Metabol Brain Dis 2013; 28(2):249-59

Thumburu KK, Taneja S, Vasishta RK, Dhiman RK. Neuropathology of acute liver failure. Neurochem Int. 2012; 60 (7): 672-5.

Duseja A, Dhiman RK, Chawla Y, Thumburu KK, Kumar A, Das A, Bhadada S, Bhansali A. Insulin resistance is common in patients with predominantly genotype 3 chronic hepatitis C. Dig Dis Sci. 2009 Aug;54(8):1778-82.

Kumar K, Chandrika A, Krishnasumanth N, Sireesha P, Rao S, Rao A. Erythrocyte glutathione and serum total glutathione-S-transferase in epilepsy. Clin Chem Lab Med. 2005;43(1):106-7

Kumar KT, Chandrika A, Sumanth KN, Sireesha P, Rao S, Rao A. Free radical toxicity and antioxidants in Guillain-Barre syndrome, a preliminary study. Clin Chim Acta. 2004 Aug 16; 346(2):205-9.

Dhiman RK, Kurmi R, Thumburu KK, Sunil VH, Agarwal R, Duseja A, Chawla Y. Diagnosis & Prognostic Significance of Minimal Hepatic Encephalopathy in Patients with Cirrhosis of Liver. Dig Dis Sci. 2010; 55(8):2381-90.

Duseja A, Das A, Dhiman RK, Chawla YK, Thumburu KK, Bhadada S, Bhansali A. Metformin is effective in achieving Biochemical Response in Patients with Non-Alcoholic Fatty Liver Disease (NAFLD) not responding to Lifestyle Interventions. Ann Hepatol. 2007 Oct-Dec; 6(4):222-6.

Duseja A, Das A, Dhiman RK, Chawla YK, Das R, Bhadada S, Sialy R, Thumburu KK, Bhansali A, Kalra N. Indian Patients with Non-Alcoholic Fatty Liver Disease presenting with Raised Transaminases are Different at Presentation. World J Gastroenterol. 2007 Jan 28; 13(4):649-50.

Systematic Reviews Published: Thumburu KK, Singh M, Das R, Jaiswal N, Agarwal A, Kumar A, Kaur H. Two or Three Primary Dose Regime for

Haemophilus Influenzae Type B Conjugate Vaccine: Meta-Analysis of Randomized Controlled Trials. Therapeutic Advances in Vaccines 2015 March; 3: 31-40.

Nishant Jaiswal, Singh M, Kondel R, Kaur N, Thumburu KK, Kumar A, Kaur H, Chadda N, Gupta N, Agarwal A, Malhotra S, Shafiq N,. Feasibility and Usefulness of Gentamicin for Use at Community Level: A Systematic Review based Guidance for Policy Decisions. World J Pediatr. 2016 Feb 1. [Epub ahead of print] PubMed PMID: 26830306

Jaiswal N, Singh M, Thumburu KK, Bharti B, Agarwal A, Kumar A, Kaur H, Chadha Burden of Invasive Pneumococcal Disease in Children aged 1 Month to 12 Years Living in South Asia: A Systematic Review. PLoS One. 2014 May 5; 9(5):e96282.

Jaiswal N, Singh M, Das RR, Jindal I, Agarwal A, Thumburu KK, Kumar A, Chauhan Distribution of serotypes, vaccine coverage, and antimicrobial susceptibility pattern of Streptococcus pneumoniae in children living in SAARC countries: a systematic review. PLoS One 2014 Sep 30;9(9):e108617.

Kumar A, Singh M, Thumburu KK, Jaiswal N, Kaur H, Sharma S, Agarwal A. Hib vaccine in India: a case for universal immunization. Vaccine. 2013 Aug 20; 31(37):3763-5.

Authoring Three Protocols for Cochrane Register Title Thumburu KK, Sing M, Jaiswal N et al. Vitamin D supplementation for treating chronic obstructive pulmonary

disease. Cochrane Systematic Reviews 2015 Jaiswal N, Sing M, Thumburu KK et al. Pallitative pharmacotherapy for severe dyspnoea in Cystic Fibrosis. Cochrane

Systematic Reviews 2014 Jaiswal N, Sing M, Thumburu KK et al. Intradermal fractional dose v/s Intramuscular full dose of polio vaccine for

prevention of polio in children. Cochrane Systematic Reviews 2014.

Book Chapters Published: Kiran K Thumburu, Manu Goyal, Nishant Jaiswal, Meenu Singh. Haemophilus Influenzae Type B Infection and

Vaccination. Evidence Based Management of respiratory Disorders in Children. Noble Vision (Medical Book Publishers). Year 2015; Page No: 18-27

Nishant Jaiswal, Meenu Singh, Kiran K Thumburu, Amit Agarwal. Pneumococcal Pneumonia. Evidence Based Management of respiratory Disorders in Children Noble Vision (Medical Book Publishers). Year 2015; Page No: 1-10

Office Bearer: Co-editor, Evidence Based Management of respiratory Disorders in Children. Noble Vision (Medical Book

Publishers). Year 2015

Grant Writing Skills (Ability to Write Grant Proposals to Funding Organizations): Written Project Proposal on "Alteration in Expression of Genes Encoding for Key Astrocytic Proteins in Patients who

have died from Acute Liver Failure and Chronic Liver Failure Associated with Hepatic Encephalopathy” to Indian Council of Medical Research (ICMR), India - Result: Grant Sanctioned for 3 Years

Written Project Proposal on " Role of Neuroinflammation in Patients with Acute Liver Failure and in Chronic Liver Failure in Patients with Cirrhosis (with Hepatic Encephalopathy): An Autopsy-Based Study” to Indian Council of Medical Research (ICMR), India - Result: Proposal Accepted

Co-investigator in a WHO Funded Project entitled “Anthropometric Measures during Infancy and Childhood and the Risk of Developing Cardiovascular Disease or Diabetes Mellitus II in Later Life: A Systematic Review” - Completed (March 2015)

PERSONAL DOSSIER

Date of Birth: 1st June, 1980 References: Available on request