40

DAFTAR PUSTAKA

1. United Nations Population Division. World population prospects: The

2002 Revision. New York: United Nations; 2003.

2. Departemen Kesehatan R.I. Mengenai masalah mental lanjut usia. [cited

2012 Oktober 2]; Available from: http://www.depkes.go.id/index.php.

3. BAPPENAS. Proyeksi Penduduk Indonesia (Indonesia Population

Projection) 2005 - 2025. Jakarta: BAPPENAS; 2008.

4. Sensus Penduduk 2010 Jakarta: Badan Pusat Statistik; c2009 [updated

2011 November 11; cited 2012 Oktober 2]; Available from:

http://sp2010.bps.go.id/index.php/site/tabel?tid=336&wid=0. .

5. KP3A. Penduduk Lanjut Usia. 2009 [cited 2012 Desember 02]; Available

from:

http://www.menegpp.go.id/aplikasidata/index.php?option=com_docman&

Itemid=114.

6. Dewi IK. Musik tradisional Bali dan musik klasik barat meningkatkan

sekresi saliva penderita xerostomia: Universitas Udayana; 2011.

7. Hasibuan S. Keluhan Mulut Kering Ditinjau dari Faktor Penyebab,

Manifestasi dan Penanggulangannya. 2002 [cited 2012 September 19];

Available from: http://library.usu.ac.id/.

8. Turner MD, Ship JA. Dry Mouth and Its Effects on the Oral Health of

Elderly People. The Journal of The American Dental Association.

2007;138:15s-6s.

9. Anggarini VR. Hubungan Penggunaan Obat Antidepresan Terhadap

Terjadinya Xerostomia pada Pasien Poli Psikiatri RSUD Dr. Ahmad

Mochtar Bukittinggi. Medan: Universitas Sumatera Utara; 2010.

41

10. Lukisari C, Kusharjanti. Xerostomia salah satu manifestasi oral diabetik.

2011 [cited 2012 September 17]; Available from: www.scribd.com.

11. Humprey SP, Williamson RT. A Review of Saliva Normal Composition,

Flow and Function. J Prosthet Dent. 2001;85(2):162-9.

12. Eugene NM, Robert LF. Salivary gland disorders. New York: Springer

Berlin Heidenberg; 2007.

13. Makkinen KK. History safety and dental properties of xylitol. 2010 [cited

2013 Januari 2013]; Available from: http://www.xylitolorg.com.

14. Yuliarsi Y, Lestari S. Efek Permen Karet yang Mengandung Xylitol dan

Sorbitol Terhadap Plak Gigi dan Ginggivitis: JITEKGI FKGUPDM 2003.

15. Martín-Piedra M, Aguilar-Salvatierra A, Herrera D, Gómez-Moreno G.

Effectiveness of a recent topical sialogogue in the management of

druginduced xerostomia. J Clin Exp Dent. 2011;3(4):e268-73.

16. Farsi NM. Signs of oral dryness in relation to salivary flow rate, pH,

buffering capacity and dry mouth complaints. BMC oral health. 2007;7:15.

17. Walsh LJ. Lifestyle Impacts on Oral Health. Queensland (Australia):

Knowledge Books and Software; 2005.

18. Pratama S. Pengaruh Pemberian Permen Karet yang Mengandung Xylitol

terhadap Laju Aliran Saliva pada Anak Usia 10-12 Tahun di Pesantren Al-

Hamidiyah Depok Tahun 2008. Jakarta: Universitas Indonesia; 2008.

19. Despopoulos A, Sibernagl S. Atlas Berwarna dan Teks Fisiologi. Jakarta:

Hipokrates; 2000.

20. Sherwood L. Fisiologi Manusia dari Sel ke Sistem. 2 ed. Jakarta: EGC;

2001.

42

21. McIntyre JM. Dental Caries-The Major Cause of Tooth Damage. 2 ed.

Queensland (Australia): Knowledge Books and Software; 2005.

22. Alam MB, Hossain MS, Chodhury NS, Mazumder MEH, Haque ME,

Islam A. In vitro and in vivo Antioxidant and Toxicity Evaluation of

Different Fractions of Oxalis corniculata Linn. Journal of Pharmacology

and Toxicology 6. 2011:337-48.

23. Gupta A, J.B E, H S. Hyposalivation in Elderly Patients. Journal of The

Canadian Dental Association. 2006;72(9):841-6.

24. Sultana N, Sham ME. Xerostomia: An overview. International Journal of

Dental Clinics. 2011;3(2):58-61.

25. Wrigley. Diagnosis of Dry Mouth: Symptoms, Signs, Causes. 2012 [cited

2013 Januari 22]; Available from:

http://www.drymouth.info/practitioner/about.asp.

26. Navazesh M, Kumar SK. Xerostomia: prevalence, diagnosis, and

management. Compend Contin Educ Dent. [Review]. 2009 Jul-

Aug;30(6):326-8, 31-2; quiz 33-4.

27. Rad M, Kakoie S, Brojeni FN, Pourdamghan N. Effect of Long-term

Smoking on Whole-mouth Salivary Flow Rate and Oral Health. Journal of

Dental Research, Dental Clinics, Dental Prospects. 2010;4(4):110-4.

28. Navazesh M, Kumar SKS. Measuring salivary flow : Challenges and

opportunities. The Journal of The American Dental Association.

2008;139:35S-40S.

29. Susan Z. Determining and Managing Salivary Gland Function in Cancer

Patients: A Fact Sheet for Dental Professionals. Oral Health Care for

Cancer Patients [serial on the Internet]. 2010.

43

30. Pierini C. Xylitol: A sweet Alternative. Vitamin Research Product; 2012

[cited 2013 Februari 09]; Available from:

http://www.vrp.com/xylitol/xylitol-a-sweet-alternative-unique-sweetener-

supports-oral-health.

31. Shellman S. Xylitol: Our Sweet Salvation? : The SPECTRUM; 2003

[cited 2013 Januari 19]; Available from:

http://www.laleva.cc/food/xylitol.html.

32. Dry Mouth (xerostomia). 2009; Available from:

http://www.orahealth.com/pages/dry-mouth-xerostomia.

33. Hasegawa H, Uozumi T, Ono K. Physiological Evaluation of Music Effect

for The Mental Workload. 2004 [cited 2012 November 29]; Available

from: http://www.idemployee.id.tue.nl/.

34. Borgnakke WS, Taylor GW, Anderson PF, Shannon MC. Dry Mouth

(Xerostomia): Diagnosis, Causes, Complications and Treatment. 2011.

35. Dewi PF. Pengaruh Konsumsi Permen Karet yang Mengandung Xylitol

Terhadap Pembentukan Plak Gigi. Semarang (Indonesia): Universitas

Diponegoro; 2008.

36. Sarwono J. Statistik Itu Mudah: Panduan Lengkap untuk Belajar

Komputasi Statistik Menggunakan SPSS 16. Yogyakarta: Penerbit

Universitas Atma Jaya Yogyakarta; 2009.

37. Nogourani MK, Isfahan RK, Beheshti MH. The effect of chewing gum’s

flavor on salivary flow rate and pH. Dental Reearch Journal.

2011;8(5):S71.

LAMPIRAN

Lampiran 1. Ethical Clearence

Lampiran 2. Ijin penelitian

Lampiran 3. Informed consent

Lampiran 4. Hasil analisis

1. Karakteristik subjek penelitian berdasarkan jenis kelamin dan usia

jenis kelamin

Frequency Percent Valid Percent Cumulative

Percent

Valid Laki-laki 3 17,6 17,6 17,6

perempuan 14 82,4 82,4 100,0

Total 17 100,0 100,0

usia

Frequency Percent Valid Percent Cumulative

Percent

Valid 60-74 10 29,4 29,4 29,4

75-90 22 64,7 64,7 94,1

>90 2 5,9 5,9 100,0

Total 34 100,0 100,0

2. Karakteristik subjek penelitian pada kelompok kontrol

Descriptive Statistics

N Minimum Maximum Mean Std.

Deviation

Pre skor XI 17 24 35 28,41 3,641

Post skor XI 17 22 34 27,24 3,580

Pre laju aliran saliva 17 ,10 ,60 ,3176 ,16099

Post laju aliran saliva 17 ,10 ,55 ,3412 ,12404

Pre skor VAS 17 0 0 ,00 ,000

Post skor VAS 17 0 0 ,00 ,000

Selisih skor XI 17 -5 4 -1,18 2,531

Selisih skor VAS 17 0 0 ,00 ,000

Selisih laju aliran saliva

17 -,30 ,30 ,0235 ,19615

Valid N (listwise) 17

3. Karakteristik subjek penelitian pada kelompok perlakuan

Descriptive Statistics

N Minimum Maximum Mean Std.

Deviation

Pre skor XI 17 28 43 32,59 3,392

Post skor XI 17 23 39 26,88 3,806

Pre laju aliran saliva 17 ,10 ,30 ,1706 ,06628

Post laju aliran saliva 17 ,15 ,50 ,3088 ,10787

Pre skor VAS 17 0 80 8,24 23,515

Post skor VAS 17 0 50 2,94 12,127

Selisih skor XI 17 -8 -4 -5,71 1,160

Selisih skor VAS 17 -80 0 -5,29 19,403

Selisih laju aliran saliva

17 ,05 ,25 ,1382 ,06502

Valid N (listwise) 17

4. Uji normalitas data kelompok kontrol

Tests of Normalityb,c,d

Kolmogorov-Smirnova Shapiro-Wilk

Statistic Df Sig. Statistic Df Sig.

Pre XI ,142 17 ,200* ,913 17 ,112

Post XI ,121 17 ,200* ,957 17 ,573

Pre laju aliran saliva

,191 17 ,101 ,931 17 ,230

Post laju aliran saliva

,212 17 ,041 ,939 17 ,304

Selisih skor XI ,117 17 ,200* ,961 17 ,647

Selisih laju alian saliva

,181 17 ,141 ,917 17 ,130

*. This is lower bound of the true significance.

a. Liliefors Significance Correction

b. pre skor VAS is constant. It has been omitted.

c. pre skor VAS is constant. It has been omitted.

d. selisih skor VAS is constant. It has been omitted.

5. Uji normalitas data kelompok perlakuan

Tests of Normality

Kolmogorov-Smirnova Shapiro-Wilk

Statistic Df Sig. Statistic Df Sig.

Pre XI ,216 17 ,033 ,814 17 ,003

Post XI ,311 17 ,000 ,739 17 ,000

Pre laju aliran saliva

,210 17 ,044 ,869 17 ,021

Post laju aliran saliva

,238 17 ,011 ,909 17 ,095

Pre skor VAS ,519 17 ,000 ,399 17 ,000

Post skor VAS ,537 17 ,000 ,262 17 ,000

Selisih skor XI ,188 17 ,111 ,925 17 ,183

Selisih skor VAS ,490 17 ,000 ,307 17 ,000

Selisih laju alian saliva

,192 17 ,095 ,917 17 ,129

a. Liliefors Significance Correction

6. Uji beda antara kelompok kontrol dan perlakuan

a. Independent t-test

Independent Samples Test

Levene’s Test for

Equality of Variances t-test for Equality of Means

F Sig. t Df Sig. (2-tailed)

Mean Difference

Std. Error

Difference

95% Confidence

Interval of The Difference

Lower Upper

Selisih

skor XI

Equal

variances assumed

9,632 ,004 6,708 32 ,000 4,529 ,675 3,154 5,905

Equal

variances not assumed

6,708 22,439 ,000 4,529 ,675 3,131 5,928

Selisih laju

aliran saliva

Equal variances

assumed

18,093 ,000 -2,289 32 ,029 -,11471 ,05012 -,21679 -,01262

Equal variances

not assumed

-2,289 19,475 ,033 -,11471 ,05012 -,21943 -,00998

b. Uji Mann Whitney

Test Statisticsb

Selisih skor

VAS

Mann-Whitney U 127,500

Wilcoxon W 280,500

Z -1,435

Asymp. Sig. (2-tailed) ,151

Exact Sig. [2*(1-tailed Sig.)]

,563a

a. Not corrected for ties b. Grouping Variable: kelompok

7. Uji normalitas data skor XI, skor VAS, dan laju aliran saliva kelompok

kontrol dan perlakuan

Tests of Normality

Kolmogorov-Smirnova Shapiro-Wilk

Statistic Df Sig. Statistic Df Sig.

Selisih skor XI ,191 34 ,003 ,930 34 ,032

Selisih laju alian saliva

,225 34 ,000 ,871 34 ,001

Selisih skor VAS ,517 34 ,000 ,195 34 ,000

a. Lilliefors Significance Correction

8. Hubungan penurunan keluhan xerostomia dan laju aliran saliva

Uji korelasi Spearman

Correlations

selisih laju

aliran saliva selisih skor XI

Spearman’s rho Selisih laju aliran saliva

Correlation Coefficient 1,000

-,349*

Sig. (2-tailed) . ,043

N 34 34

Selisih skor XI Correlation Coefficient -,349* 1,000

Sig. (2-tailed) ,043 .

N 34 34

*. Correlation is significant at the 0.05 level (2-tailed)

Correlations

selisih laju

aliran saliva selisih skor VAS

Spearman’s rho Selisih laju aliran saliva

Correlation Coefficient 1,000

-,043

Sig. (2-tailed) . ,811

N 34 34

Selisih skor VAS Correlation Coefficient -,043

1,000

Sig. (2-tailed) ,811 .

N 34 34

Lampiran 5. Kuesioner XI dan VAS

Lampiran 6. Formulir data sampel

Lampiran 7. Dokumentasi penelitian

Lampiran 8. Biodata mahasiswa

Identitas

Nama : Annisa Rizqi

NIM : G2A009172

Tempat/tanggal lahir : Pati, 9 Mei 1991

Jenis kelamin : Perempuan

Alamat : Jl. Gergaji IV No.1114A Semarang

Nomor Telepon : -

Nomor HP : 085727787729

e-mail : anicehopes@gmail.com

Riwayat Pendidikan Formal

1. SD : SD Pati Kidul 01 Lulus tahun: 2000

2. SMP : SMP N 3 Pati Lulus tahun: 2006

3. SMA : SMA N 1 Pati Lulus tahun: 2009

4. FK UNDIP : Masuk tahun : 2009

Keanggotaan Organisasi

1. Asisten Farmakologi FK Undip Tahun 2012 s/d 2013

2. Sie logistik Scientific Fair FK Undip Tahun 2011

Pengalaman mengikuti lomba karya ilmiah

1. Anis Rahmawati, Annisa Rizqi, Atika Nurmalitasari, Bagus Indra Cahya:

Pengaruh Pemberian Permen Karet yang Mengandung Xylitol terhadap

Penurunan Keluhan Mulut Kering (Xerostomia) pada Pasien Paskaterapi

Radiasi Kepala Leher dan Usia Tua. (didanai Dikti)