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Penyakit Virus

Virus > DNA > RNA Virus DNA :

- Poxviridae : >Variola >Moluskum

kontangiosum- Herpetoviridae : >Herpes simpleks

>Herpes oster >Varisela

-Papovaviridae : >Veruka >!ondilomaakuminata

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Virus RNA :

- "rt#omyxoviridae $ in%luena- Paramyxoviridae $ mor&ili

' Herpes simpleks

!ulit( selaput lendir

Penye&aran : mell udara( kontak

langsung

)ipe * mata + rongga mulut)ipe ** $ genital

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*n%eksi :

- Primer : rasa sakit, vesikel ./, erosi ./ 0-1

mgg- !am&u#an rekuren/ : tidak &egitu sakit,

vesikel + erosi l ke2il( sedikit

3aktor-%aktor kekam&u#an :

kelela#an %isik, stress psikis, mnm alko#ol,

makanan, mens, trauma 4ak tu koitus

Pengo&atan :

- Asiklovir - *D5iodo-0deoksiuridin/- *soprenosin - *nter%eron

- 6upidon H tp */

- 6upidon 7 tp **/ - Vidara&ine

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Herpes 7enitalis

8tiologi : Virus Herpes simpleks tipe **

Masa inku&asi : 0 9 #r

Dapat rekuren

*n%eksi inisial primer/ :- demam, vesikel infeksius fase laten

ganglion sakralis

*n%eksi rekuren :

- Ada %aktor pen2etus, dpt setiap minggu,&ulan atau ta#un

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!omplikasi Herpes 7enitalis :

6im%adenitis ;gk pendek/, depresi + gelisa# ;gk

pan;ang/,

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Herpes Boster "rang tua

Reaktivasi virus varisela

7am&aran klinis :

akit ./, parestesi ./, erupsi lokalisata, unilateral,

makulo- papula yg eritemC0-0 ;am $Vesikel$Pustula$!rusta

HB o%talmika, servikalis, torakalis, lum&alis, otikum

Pengo&atan : -simptomatik -Prednison

-*soprenosin -Asikovir

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Varisela = 2a2ar air

in% primer

Virus varisela osterin% kambuhan (rekuren)Herpes Zoster

Varisela- gejala prodromal : Demam (3-3! ")

- Vesikel # tetesan embun

$ustula krusta% $olimorf% &entrifugal

$engobatan : -simptomatis -inf sekunder 'ntibiotika

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A

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78GA6A A*D

Ringan :

- )rom&ositopenia

- Diare > 0 mgg

- u#u > I < slm > C

&ln- Rasa lela#

- Na%su makanan

&erkurang, JJ turun

C?@ dlm C &ulan

A*D :

- Pneumo2ystis 2arinii

- !andidiasis eso%agus

- Herpes dengan

ulserasi- arkoma kaposi

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Etiologi

Human Retrovirus : HIV 1 , HIV 2

Tersering HIV-1

HIV 2 kurang infeksius Jenis subtipe : , !, ", #, E, $, %, H

&, J 'an (

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Situasi HIV/AIDS di Indonesia

1987 s/d Desember 2008Jumlah Tercatat

di Deartemen !esehatan "I #

AIDS # 1$%110 &asus

HIV # $%01' &asus

Total # 22%12' &asus

(stimasi )oulasi "a*an Tertular HIV Tahun

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CARA-CARA PENULARAN

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Assuming an HIV-positivesource, what is the risk of acquiring HIV infection for

the following types of exposure?http://wwwashmorgau/pep/

!ype of exposure "stimate# risk per exposure$%&

Jlood )rans%usion per in%e2ted unit/ C(CK0

Mot#er-to-2#ild 4it#out intervention/ C(

Re2eptive anal inter2ourse RA*/ C(C0?

5se o% 2ontaminated in;e2ting eLuipment C(C?

"22upational needle sti2k in;ury C(

Re2eptive vaginal inter2ourse C(C,??? 0

*nsertive anal or vaginal inter2ourse C(C,???

*+hese estimates are based on prospe,tie studies. not ,ross-se,tional data or /gures deried from modelling%0* +his estimate has been rounded from 1!2! to 1222%

isk of +ransmission

http://www.ashm.org.au/pep/http://www.ashm.org.au/pep/http://www.ashm.org.au/pep/http://www.ashm.org.au/pep/

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3 - 6BULAN

3 - 10 - 15TAHUN 1 - 2 TAHUN

PeriodeJendela

HIV + AIDS

Tertlar

2-3 !"" terin#e$%i&

'e(ala %e)erti *

Tan)a "e(ala &

A$tita%nor!al

'e(ala&Diare-Berat Badantrn-De!a!-'"n %ara#-Par-

,lit-lt-(a!r-

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Seroconversion

Fever

Myalgia

ArthralgiaAdenopathy

Malaise

Rash

Meningitis

Guillain-Barre Syndrome

CIDP

Thromo!ytopenia

Rea!tive arthritisPolymyositis

Bell"s palsy

S#ogren"s syndrome

Se dermatitis

Gingivitis

$arts

Mollus!umTB

%erpes &oster

Sinusitis

%erpes simple'

Candidiasis

%airy leu(opla(ia

PCP

To'oplasmosis

Cryptosporidiosis

Crypto!o!!osisMAC

CM)

*aposi"s sar!oma

+ymphoma

Cervi!al !an!er

222

22

422

522

022

2

"D5,ells1mm3

0 3 5 6 4 0 5 4 27onths 8ears9posure

;indo< periode H=V $ositie

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Pengo&atan

nti Retroviral

Infeksi&pportunistik

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Infeksi &portunistik

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)E*T+H( !ER&!T HIV

HIV a'ala penakit kronis ang memerlukanpengobatan .angka pan.ang :

*engobatanantiretroviral /RVs0

*engobatan *rofilaksis untuk infeksioportunistik

*engobatan infeksi oportunistik /terutamatuberkulosis T!0

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Makna H*V-"ral &agi dokter gigi

*ndikasi status in%eksi H*V

e&agai ge;ala klinis a4al H*V

Predileksi progresi%itas menu;u A*D 8ntry ( end points untuk terapi atau trial

vaksin

!lasi%ikasi dan staging system

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Masala# gilut "DHA R

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!e&utu#an pera4atan gilut "DHA

*rmagita dkk, 0??O/

Pem&ersi#an karang gigi C?? @

Pen2a&utan gigi OC @

Pera4atan karies gigi IO @ 7igi tiruan OI @

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H*V-"ral pd "DHA dg AR) di

Poksidus A*D *K*nda# dkk, 0??O/

C dari OI "DHA dg AR) terdapat H*V-"ralK

6esi H*V-"ral ter&anyak "ral Hairy6eukoplakia dan Pseudomem&ranous