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Penyakit Virus
Virus > DNA > RNA Virus DNA :
- Poxviridae : >Variola >Moluskum
kontangiosum- Herpetoviridae : >Herpes simpleks
>Herpes oster >Varisela
-Papovaviridae : >Veruka >!ondilomaakuminata
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Virus RNA :
- "rt#omyxoviridae $ in%luena- Paramyxoviridae $ mor&ili
' Herpes simpleks
!ulit( selaput lendir
Penye&aran : mell udara( kontak
langsung
)ipe * mata + rongga mulut)ipe ** $ genital
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*n%eksi :
- Primer : rasa sakit, vesikel ./, erosi ./ 0-1
mgg- !am&u#an rekuren/ : tidak &egitu sakit,
vesikel + erosi l ke2il( sedikit
3aktor-%aktor kekam&u#an :
kelela#an %isik, stress psikis, mnm alko#ol,
makanan, mens, trauma 4ak tu koitus
Pengo&atan :
- Asiklovir - *D5iodo-0deoksiuridin/- *soprenosin -
*nter%eron
- 6upidon H tp */
- 6upidon 7 tp **/ - Vidara&ine
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Herpes 7enitalis
8tiologi : Virus Herpes simpleks tipe **
Masa inku&asi : 0 9 #r
Dapat rekuren
*n%eksi inisial primer/ :- demam, vesikel infeksius fase
laten
ganglion sakralis
*n%eksi rekuren :
- Ada %aktor pen2etus, dpt setiap minggu,&ulan atau
ta#un
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!omplikasi Herpes 7enitalis :
6im%adenitis ;gk pendek/, depresi + gelisa# ;gk
pan;ang/,
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Herpes Boster "rang tua
Reaktivasi virus varisela
7am&aran klinis :
akit ./, parestesi ./, erupsi lokalisata, unilateral,
makulo- papula yg eritemC0-0 ;am $Vesikel$Pustula$!rusta
HB o%talmika, servikalis, torakalis, lum&alis, otikum
Pengo&atan : -simptomatik -Prednison
-*soprenosin -Asikovir
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Varisela = 2a2ar air
in% primer
Virus varisela osterin% kambuhan (rekuren)Herpes Zoster
Varisela- gejala prodromal : Demam (3-3! ")
- Vesikel # tetesan embun
$ustula krusta% $olimorf% &entrifugal
$engobatan : -simptomatis -inf sekunder 'ntibiotika
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A
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78GA6A A*D
Ringan :
- )rom&ositopenia
- Diare > 0 mgg
- u#u > I < slm > C
&ln- Rasa lela#
- Na%su makanan
&erkurang, JJ turun
C?@ dlm C &ulan
A*D :
- Pneumo2ystis 2arinii
- !andidiasis eso%agus
- Herpes dengan
ulserasi- arkoma kaposi
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7/24/2019 Dermato 5
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Etiologi
Human Retrovirus : HIV 1 , HIV 2
Tersering HIV-1
HIV 2 kurang infeksius Jenis subtipe : , !, ", #, E, $, %, H
&, J 'an (
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Situasi HIV/AIDS di Indonesia
1987 s/d Desember 2008Jumlah Tercatat
di Deartemen !esehatan "I #
AIDS # 1$%110 &asus
HIV # $%01' &asus
Total # 22%12' &asus
(stimasi )oulasi "a*an Tertular HIV Tahun
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CARA-CARA PENULARAN
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Assuming an HIV-positivesource, what is the risk of acquiring
HIV infection for
the following types of exposure?http://wwwashmorgau/pep/
!ype of exposure "stimate# risk per exposure$%&
Jlood )rans%usion per in%e2ted unit/ C(CK0
Mot#er-to-2#ild 4it#out intervention/ C(
Re2eptive anal inter2ourse RA*/ C(C0?
5se o% 2ontaminated in;e2ting eLuipment C(C?
"22upational needle sti2k in;ury C(
Re2eptive vaginal inter2ourse C(C,??? 0
*nsertive anal or vaginal inter2ourse C(C,???
*+hese estimates are based on prospe,tie studies. not
,ross-se,tional data or /gures deried from modelling%0* +his
estimate has been rounded from 1!2! to 1222%
isk of +ransmission
http://www.ashm.org.au/pep/http://www.ashm.org.au/pep/http://www.ashm.org.au/pep/http://www.ashm.org.au/pep/
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3 - 6BULAN
3 - 10 - 15TAHUN 1 - 2 TAHUN
PeriodeJendela
HIV + AIDS
Tertlar
2-3 !"" terin#e$%i&
'e(ala %e)erti *
Tan)a "e(ala &
A$tita%nor!al
'e(ala&Diare-Berat Badantrn-De!a!-'"n %ara#-Par-
,lit-lt-(a!r-
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Seroconversion
Fever
Myalgia
ArthralgiaAdenopathy
Malaise
Rash
Meningitis
Guillain-Barre Syndrome
CIDP
Thromo!ytopenia
Rea!tive arthritisPolymyositis
Bell"s palsy
S#ogren"s syndrome
Se dermatitis
Gingivitis
$arts
Mollus!umTB
%erpes &oster
Sinusitis
%erpes simple'
Candidiasis
%airy leu(opla(ia
PCP
To'oplasmosis
Cryptosporidiosis
Crypto!o!!osisMAC
CM)
*aposi"s sar!oma
+ymphoma
Cervi!al !an!er
222
22
422
522
022
2
"D5,ells1mm3
0 3 5 6 4 0 5 4 27onths 8ears9posure
;indo< periode H=V $ositie
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Pengo&atan
nti Retroviral
Infeksi&pportunistik
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Infeksi &portunistik
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)E*T+H( !ER&!T HIV
HIV a'ala penakit kronis ang memerlukanpengobatan .angka pan.ang
:
*engobatanantiretroviral /RVs0
*engobatan *rofilaksis untuk infeksioportunistik
*engobatan infeksi oportunistik /terutamatuberkulosis T!0
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Makna H*V-"ral &agi dokter gigi
*ndikasi status in%eksi H*V
e&agai ge;ala klinis a4al H*V
Predileksi progresi%itas menu;u A*D 8ntry ( end points untuk
terapi atau trial
vaksin
!lasi%ikasi dan staging system
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Masala# gilut "DHA R
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!e&utu#an pera4atan gilut "DHA
*rmagita dkk, 0??O/
Pem&ersi#an karang gigi C?? @
Pen2a&utan gigi OC @
Pera4atan karies gigi IO @ 7igi tiruan OI @
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H*V-"ral pd "DHA dg AR) di
Poksidus A*D *K*nda# dkk, 0??O/
C dari OI "DHA dg AR) terdapat H*V-"ralK
6esi H*V-"ral ter&anyak "ral Hairy6eukoplakia dan
Pseudomem&ranous
