吉良潤一業績目録 - 九州大学（KYUSHU UNIVERSITY） · Web viewJun-ichi Kira, Kyushu Univeristy List of Publication in English Original Article 2 63 (1’ Author 35) Case

吉良潤一　業績目録

April 2013

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Jun-ichi Kira, Kyushu Univeristy

List of Publication in English

Original Article 263 (1’ Author 35)

Case Report36 (0)

Review

20 (15)

Books 12 (4)

Total 331 (54)

I. Original Article

1985

1. Kira J, Deibler GE, Krutzsch HC, Martenson RE:

Amino acid sequence of porcine myelin basic protein.

J Neurochem 44: 134-142, 1985

2. Kobayashi T, Kira J, Shinno N, Goto I, Kuroiwa Y:

Fabry’s disease with partially deficient hydrolysis of ceramide trihexoside.

J Neurol Sci 67: 179-185, 1985

1986

3. Kira J, Bacon ML, Martenson RE, Deibler GE, Kies MW, Alvord ECJr:

Experimental allergic encephalomyelitis in rabbits: a major encephalitogenic determinant within residues 1-44 of myelin basic protein.

J Neuroimmunol 12: 183-193, 1986

4. Driscoll BF, Kira J, Kies MW, Alvord ECJr:

Mechanism of demyelination in the guinea pig: separate sensitization with encephalitogenic myelin basic protein and nonencephalitogenic brain components.Neurochem Pathol 4: 11-22, 1986

1987

5. Kira J, Itoyama Y, Goto I:

Surface phenotypic changes of spleen cells on aquisition of encephalitogenicity.


1988

6. Kira J, Minato S, Itoyama Y, Goto I, Kato M, Hasuo K:

Leukoencephalopathy in HTLV-I-associated myelopathy: MRI and EEG data.

J Neurol Sci 87: 221-232, 1988


Relationship between surface marker expression and encephalitogenic potency of BP-cultured lymphocytes.

Cell Immunol 112: 14-26, 1988

8. Itoyama Y, Minato S, Kira J, Goto I, Sato H, Okochi K, Yamamoto N:

Altered subsets of peripheral blood lymphocytes in patients with HTLV-I-associated myelopathy.

Neurology 38: 816-818, 1988


Spontaneous proliferation of peripheral blood lymphocytes increased in patients with HTLV-I-associated myelopathy.

Neurology 38: 1302-1307, 1988

1989


Generation of CD4+ blastoid T cells showing marked upregulation of CD4, class I and II MHC and IL2 receptor molecules is required for the potent encephalitogenicity.

Cell Immunol 123: 264-275, 1989

11. Itoyama Y, Kira J, Fujii N, Goto I, Yamamoto N:

Increases in helper inducer T cells and activated T cells in HTLV-I-associated myelopathy.

Ann Neurol 26: 257-262, 1989

12. Minato S, Itoyama Y, Fujii N, Kira J, Goto I, Yamamoto N:

Activated T cells in HTLV-I-associated myelopathy: autologous mixed lymphocyte reaction.

Ann Neurol 26: 398-401, 1989

1990


Generation of CD4+ blastoid T cells in recipients of BP/IFA- sensitized spleen cells.

Cell Immunol 128: 130-141, 1990

1991

14. Kira J, Koyanagi Y, Yamada T, Itoyama Y, Goto I, Yamamoto N, Sasaki H, Sakaki Y:

Increased HTLV-I proviral DNA in HTLV-I-associated myelopathy: a quantitative polymerase chain reaction study.

Ann Neurol 29: 194-201, 1991

15. Kira J, Harada M, Yamaguchi Y, Shida N, Goto I:

Hyperprolactinemia in multiple sclerosis.

J Neurol Sci 102: 61-66, 1991

16. Kira J, Koyanagi Y, Hamakado T, Itoyama Y, Yamamoto N, Goto I:

HTLV-II in patients with HTLV-I-associated myelopathy.

Lancet 2: 64-65, 1991

17. Kira J, Fujihara K, Itoyama Y, Goto I, Hasuo K:

Leukoencephalopathy in HTLV-I-associated myelopathy/tropical spastic paraparesis: MRI analysis and a two year follow-up study after corticosteroid therapy.

J Neurol Sci 106: 41-49, 1991

18. Nakamura M, Kuroki M, Kira J, Itoyama Y, Shiraki H, Kuroda N, Washitani Y, Nakano S,

Nagafuchi S, Anzai K, Tatsumoto T, Esaki T, Maeda Y, Niho Y:

Elevated antibodies to synthetic peptides of HTLV-I envelope transmembrane glycoproteins in patients with HAM/TSP.


1992

19. Kira J, Nakamura M, Sawada T, Koyanagi Y, Ohori N, Itoyama Y, Yamamoto N, Sakaki Y, 　Goto I:

Antibody titers to HTLV-I-p40 tax and gag-env hybrid protein in HTLV-I-associated myelopathy/tropical spastic paraparesis: correlation with increased HTLV-I proviral DNA load.

J Neurol Sci 107: 98-104, 1992

20. Kira J, Itoyama Y, Koyanagi Y, Tateishi J, Kishikawa M, Akizuki S, Kobayashi I, Toki N, Sueishi K, Sato H, Sakaki Y, Yamamoto N, Goto I:

Presence of HTLV-I proviral DNA in central nervous system of patients with HTLV-I-associated myelopathy

Ann Neurol 31: 39-45, 1992

21. Nakamura M, Itoyama Y, Kuroki M, Nakano S, Kondoh S, Nagafuchi S, Kira J, Ichinose I,　Mitsugi K, Anzai K, Mori H, Fukui M, Okamura S, Niho Y:

Increase of peripheral B lymphocytes committed to the production of monoreactive and high affinity antibodies to HTLV-I in patients with HAM/TSP.


1993

22. Kira J, Goto I, Otsuka M, Ichiya Y:

Chronic progressive spinocerebellar syndrome associated with antibodies to human T-lymphotropic virus type I: clinico-virological and magnetic resonance imaging studies.

J Neurol Sci 115: 111-116, 1993

23. Kira J, Tobimatsu S, Goto I, Hasuo K:

Primary progressive versus relapsing remitting multiple sclerosis in Japanese patients: a combined clinical, magnetic resonance imaging and multimodality evoked potential study.

J Neurol Sci 117: 179-185, 1993

24. Koyanagi Y, Itoyama Y, Nakamura N, Takamatsu K, Kira J, Iwamasa T, Goto I, Yamamoto N:

In vivo infection of human T-cell leukemia virus type I in non-T cells.

J Virol 196: 25-33, 1993

1994

25. Kira J, Koyanagi Y, Yamada T, Itoyama Y, Tateishi J, Akizuki S, Kishikawa M, Baba E, Nakamura M, Suzuki J, Nakamura N, Yamamoto N, Goto I:

Sequence heterogeneity of HTLV-I proviral DNA in the central nervous system of patients with HTLV-I-associated myelopathy.

Ann Neurol 36: 149-156, 1994

26. Kira J, Tobimatsu S, Goto I:

Vitamin B12 metabolism and massive dose methyl B12 therapy in Japanese patients with multiple sclerosis.

Intern Med 33: 82-86, 1994

27. Kira J, Goto I:

Recurrent opticomyelitis associated with anti-DNA antibody.

J Neurol Neurosurg Psychiatry 57: 1124-1125, 1994

28. Kira J:

The presence of HTLV-I proviral DNA in the central nervous system of patients with HTLV-I-associated myelopathy/tropical spastic paraparesis.

Molecular Neurobiol 8: 139-145, 1994

29. Yu F, Itoyama Y, Kira J, Fujihara K, Kobayashi T, Kitamoto T, Suzumura A, Yamamoto N, Nakajima Y, Goto I:

TNF-beta produced by human T lymphotropic virus type I-infected cells influences the proliferation of human endothelial cells and fibroblasts.

J Immunol 152: 5930-5939, 1994

30. Hasuo K, Uchino A, Matsumoto S, Yoshida K, Kira J, Masuda K:

Magnetic resonance imaging in a juvenile type of distal and segmental atrophy of the upper extremities.

Eur Radiol 4: 119-124, 1994

1995

31. Godoy AJ, Kira J, Hasuo K, Goto I:

Characterization of cerebral white matter lesions of HTLV-I-associated myelopathy/tropical spastic paraparesis in comparison with multiple sclerosis and collagen-vascultis: a semiquantitative MRI study.

J Neurol Sci. 133: 102-111, 1995

32. Kawano Y, Kira J:

Chronic hypertrophic cranial pachymeningitis associated with HTLV-I infection.


33. Murai H, Inaba S, Kira J, Yamamoto A, Ohno M, Goto I:

Hepatitis C virus associated cryoglobulinemic neuropathy successfully treated with plasma exchange.

Artificial Organs 19: 334-338, 1995

34. Baba E, Nakamura M, Ohkuma K, Kira J, Tanaka Y, Nakano S, Niho Y:

A peptide-based human T cell leukemia virus type I vaccine containing T and B cell epitopes that induces high titers of neutralizing antibodies.

J Immunol 154: 399-412, 1995

1996

35. Kira J, Kanai T, Nishimura Y, Yamasaki K, Matsushita S, Kawano Y, Hasuo K, Tobimatsu S, Kobayashi T:

Western versus Asian types of multiple sclerosis: immunogenetically and clinically distinct disorders.

Ann Neurol 40: 569-574, 1996

36. Suzuki J, Kira J, Baba E, Nakamura M, Koyanagi Y, Nakamura T, Kawano Y, Yamasaki K, Shirabe S, Hatano N, Hayashi K, Yamamoto N, Kobayashi T:

The association of antibodies against HTLV-I pX-gene mutant products with HTLV-I-associated myelopathy (HAM)/tropical spastic paraparesis (TSP).

J Infect Dis 173:1115-1122, 1996

1997

37. Kira J, Inuzuka T, Hozumi I, Wada H, Tanaka K, Gondo H, Sato S, Tsuji S, Kobayashi T:

A novel monoclonal antibody which reacts with a high-molecuar-Weight neuronal cytoplasmic protein and myelin basic protein (MBP) in a patient with macroglobulinemia.

J Neurol Sci 148: 47-52, 1997

38. Kira J, Yamasaki K, Kawano Y, Kobayashi T:

Acute myelitis associated with hyperIgEemia and atopic dermatitis.

J Neurol Sci 148: 199-203, 1997

39. Kira J, Kawano Y:

Recurrent optic neuromyelitis with endocrinopathies.

Neurology 49: 1475-1476, 1997

40. Kira J, Yamasaki K, Yamamoto I, Mizusawa H, Yoshino S, Kusunoki S, Yoshida T, Koyanagi Y, Tanaka Y, Kawano Y, Nakamura M, Tsuneyoshi M, Yamamoto N, Kobayashi T:

Induction of chronic inflammatory arthropathy and mesenchymal tumors in rats infected　with human T cell lymphotropic virus type I.

J Acquir Immun Defic Syndr Hum Retrovirol 16: 380-392, 1997

41. Yamasaki Y, Kira J, Koyanagi Y, Kawano Y, Miyano-Kurosaki N, Nakamura M, Baba E, Suzuki J, Yamamoto A, Yamamoto N, Kobayashi T:

Long term, high dose interferon-alpha treatment in HTLV-I-associated myelopathy/tropical spastic paraparesis: a combined clinical, virological and immunological study.

J Neurol Sci 147: 135-144, 1997

42. Koyanagi Y, Tanaka Y, Kira J, Ito M, Hioki K, Misawa N, Kawano Y, Yamasaki K, Tanaka　R, Suzuki Y, Ueyama Y, Terada E, Tanaka T, Miyasaka M, Kobayashi T, Kumazawa Y, Yamamoto N:

Primary human immunodeficiency virus type 1 viremia and central nervous system invasion in a novel hu-PBL-immunodeficient mouse strain.

J Virol 71: 2417-2424, 1997

43. Kira J, Hamada T, Okayama M, Yamasaki K:

An association of human T-cell lymphotropic virus type I infection with vascular dementia.

Acta Neurol Scand 96: 305-309, 1997

44. Kawano Y, Tanaka Y, Misawa N, Tanaka R, Kira J, Kimura T, Fukushi M, Sano K, Goto T, Nakai M, Kobayashi T, Yamamoto N, Koyanagi Y:

Mutational analysis of human immunodeficiency virus type 1 (HIV-1) accessory genes: requirement of a site in the nef gene for HIV-1 replication in activated CD4+ T cells in vitro and in vivo.

J Virol 71: 8456-8466, 1997

1998

45. Imaiso Y, Taniwaki T, Yamada T, Yoshimura T, Hirano M, Ueno S, Kaneda N, Kira J:

A novel mutation of the GTP-cyclohydrolase I gene in a patient with hereditary progressive dystonia/dopa-responsive dystonia.

Neurology 50: 517-519, 1998

46. Kira J, Kawano Y, Yamasaki K, Tobimatsu S:

Acute myelitis with hyperIgEaemia and mite antigen specific IgE: atopic myelitis.


47. Kira J, Kawano Y, Yamasaki K:

Multiple sclerosis with mite antigen specific IgE.

J Neurol Sci 157: 138-142, 1998

48. Sugimoto N, Ito D, Tanaka K, Matsuda H, Saito H, Sakai H, Fujihara K, Itoyama Y, Yamada T, Kira J, Matsumoto R, Mori M, Nagashima K, Yogo Y:

Amplification of JC virus regulatory DNA sequences from cerebrospinal fluid: diagnostic values for progressive multifocal leukoencephalopathy.

Arch Virol 143: 249-262, 1998

49. Nagano S, Yamada T, Shinnoh N, Furuya H, Taniwaki T, Kira J:

Expression and processing of recombinant human galactosylceramidase.

Clin Chim Acta 276: 53-61, 1998

50. Wataya K, Akanuma J, Cavadini P, Aoki Y, Kure S, Invernizzi F, Yoshida I, Yoshino M, Kira J, Taroni F, Matsubara Y, Narisawa K:

Two CPT2 mutations in three Japanese patients with carnitine palmitoyltransferase II deficiency: functional analysis and association with polymorphic haplotypes and two clinical phenotypes.

Hum Mut 11: 377-386, 1998

51. Ito H, Yamasaki K, Kawano Y, Horiuchi I, Yun C, Nishimura Y, Kira J:

HLA-DP-associated susceptibility to optico-spinal form of multiple sclerosis in the Japanese.

Tissue Antigens 52: 179-182, 1998

52. Taniwaki T, Yamada T, Yoshida T, Sasaki M, Kuwabara Y, Nakagawa M, Mihara F, Motomura S, Shigetoh H, Kira J:

Heterogeneity of glucose metabolism in corticobasal degeneration.

J Neurol Sci 161: 70-76, 1998

53. Ono T, Zambenedetti MR, Yamasaki K, Kawano Y, Ito H, Kamikawaji N, Sakurai M, Nishimura Y, Kira J, Kanazawa I, Sasazuki T:

Molecular analysis of HLA class I (HLA-A and -B) and HLA class II (HLA-DRB1) genes in Japanese patients with multiple sclerosis (Western type and Asian type).


1999

54. Kira J, Kawano Y, Horiuchi I, Yamada T, Imayama S, Furue M, Yamasaki K:

Clinical, immunological and MRI features of myelitis with atopic dermatitis (atopic myelitis).

J Neurol Sci 162: 56-61, 1999

55. Taniwaki T, Yamada T, Asahara H, Ohyagi Y, Kira J:

Ceramide induces apoptosis to immature cerebellar granule cells in culture.

Neurochem Res 24: 685-690, 1999

56. Yamada T, Taniwaki T, Shinnoh N, Uchiyama A, Shimozawa N, Ohyagi Y, Asahara H, Kira J:

Adrenoleukodystrophy protein enhances association of very long-chain acyl-coenzyme A synthetase with the peroxisome.

Neurology 52: 614-616, 1999

57. Tanaka K, Suga R, Yamada T, Tobimatsu S, Sasaki M, Kuwabara Y, Furuya H, Kobayashi T, Kira J:

Idiopathic cortical myoclonus restricted to the lower limbs: unique correlation between MEPs and a 99mTc-ECD SPECT activation study.

J Neurol Sci 163: 58-60, 1999

58. Kikuchi H, Doh-ura K, Kawashima T, Kira J, Iwaki T:

Immunohistochemical analysis of spinal cord lesions in amyotrophic lateral sclerosis using microtubule associated protein 2 (MAP2) antibodies.

Acta Neuropathol 97: 13-21, 1999

59. Tanaka K, Yamada T, Kikuchi H, Mitsunaga Y, Furuya H, Kira J:

Autosomal dominant limb-girdle muscular dystrophy with ankle joint contracture.


60. Kikuchi H, Doh-ura K, Kira J, Iwaki T:

Preferential neurodegeneration in the cervical spinal cord of progressive supranuclear palsy.


61. Arakawa K, Tobimatsu S, Kira J, Kato M:

Parvocellular and magnocellular visual processing in spinocerebellar degeneration and Parkinson’s disease: an event-related potential study.

Clinical Neurophysiol 110: 1048-1057, 1999

62. Maeda N, Koyanagi Y, Misawa N, Miyano-Kurosaki N, Kira J, Yamamoto N:

Acquisition of HIV type 1 resistance by –chemokine-producing CD4+ T cells.

AIDS Research and Human Retroviruses 15: 1453-1460, 1999

63. Asahara H, Taniwaki T, Ohyagi Y, Yamada T, Kira J:

Glutamate enhances phosphorylation of neurofilaments in cerebellar granule cell culture.

J Neurol Sci 171: 84-87, 1999

64. Arakawa K, Tobimatsu S, Tomoda H, Kira J, Kato M:

The effects of spatial frequency on chromatic and achromatic steady-state visual evoked potentials.

Clin Neurophysiol 110: 1959-1964, 1999

65. Yamasaki K, Horiuchi I, Minohara M, Kawano Y, Ohyagi Y, Mihara F, Ito H, Nishimura Y, Kira J:

HLA-DPB1*0501-associated opticospinal multiple sclerosis: clinical, neuroimaging and immunogenetic studies.

Brain 122: 1689-1696, 1999

66. Horiuchi I, Kawano Y, Yamasaki K, Matsuo H, Minohara M, Nakamura T, Hashiguchi H, Ohyagi Y, Yamada T, Kira J:

Heightened IgE response to mite antigens in inflammatory neuropathies.

J Neurol Sci 166: 77-80, 1999

67. Suga R, Tobimatsu S, Kira J, Kato M:

Motor and somatosensory evoked potential findings in HTLV-I-associated myelopathy.

J Neurol Sci 167: 102-106, 1999

68. Ikezoe K, Yoshimura T, Taniwaki T, Matsuura E, Furuya H, Yamada T, Nagamatsu K, Kira J:

Autosomal dominant familial spinal and bulbar muscular atrophy with gynecomastia.

Neurology 53: 2187-2189, 1999

69. Kira J, Yamasaki K, Horiuchi I, Ohyagi Y, Taniwaki T, Kawano Y:

Changes in the clinical phenotypes of multiple sclerosis during the past 50 years in Japan.

J Neurol Sci 166: 53-57, 1999

2000

70. Horiuchi I, Kawano Y, Yamasaki K, Minohara M, Furue M, Taniwaki T, Miyazaki T, Kira J:

Th1 dominance in HAM/TSP and the optico-spinal form of multiple sclerosis versus Th2 dominance in mite antigen-specific IgE myelitis.

J Neurol Sci 172: 17-24, 2000

71. Yamasaki K, Horiuchi I, Minohara M, Osoegawa M, Kawano Y, Ohygai Y, Yamada T, Kira J:

Hyperprolactinemia in opticospinal multiple sclerosis.

Intern Med 39: 296-299, 2000

72. Ohyagi Y, Yamada T, Nishioka K, Clarke NJ, Tomlinson AJ, Naylor S, Nakabeppu Y, Kira J, Younkin SG:

Selective increase in cellular A42 is related to apoptosis but not necrosis.

NeuroReport 11: 167-171, 2000

73. Arakawa K, Tobimatsu S, Kurita-Tashima S, Nakayama M, Kira J, Kato M:

Effects of stimulus orientation on spatial frequency function of the visual evoked potential.

Exp Brain Res 131: 121-125, 2000

74. Ohyagi Y, Yamada T, Okayama A, Sakae N, Yamasaki T, Ohshima T, Sakamoto T, Fujii N, Kira J:

Vergence disorders in patients with spinocerebellar ataxia 3/Machado-Joseph disease: a synoptophore study.

J Neurol Sci 173 (2): 120-123, 2000

75. Fukazawa T, Yamasaki K, Ito H, Kikuchi S, Minohara M, Horiuchi I, Tsukishima E, Sasaki H, Hamada T, Nishimura Y, Tashiro K, Kira J:

Both the HLA-DPB1 and –DRB1 alleles correlate with risk for multiple sclerosis in Japanese: Clinical phenotypes and gender as important factors.


76. Horiuchi I, Yamasaki K, Osoegawa M, Ohyagi Y, Okayama A, Kurokawa T, Yamada T,

Kira J:

Acute myelitis after asthma attacks with onset after puberty.


77. Wu X-M, Osoegawa M, Yamasaki K, Kawano Y, Ochi H, Horiuchi I, Minohara M, Ohyagi Y, Yamada T, Kira J:

Flow cytometric differentiation of Asian and Western types of multiple sclerosis (MS), HTLV-1-associated myelopathy/tropical spastic paraparesis (HAM/TSP) and hyperIgEaemic myelitis by analyses of memory CD4 positive T cell subsets and NK cell subsets.

J Neurol Sci 177: 24-31, 2000

78. Yamada T, Shinnoh N, Taniwaki T, Ohyagi Y, Asahara H, Horiuchi I, Kira J:

Lovastatin does not correct the accumulation of very long-chain fatty acids in tissues of adrenoleukodystrophy protein-deficient mice.

J Inher Metab Dis 23: 607-614, 2000

79. Tsujino S, Kanazawa N, Ohashi T, Eto Y, Saito T, Kira J, Yamada T:

Three Novel mutation (G27E, insAAC, R179X) in the ORNT1 gene of Japanese patients with hyperornithinemia, hyperammonemia, and homocitrullinuria syndrome.

Ann Neurol 47: 625-631, 2000

80. Yamada T, Shinnoh N, Kondo A, Uchiyama A, Shimozawa N, Kira J, Kobayashi T:

Very-long-chain fatty acid metabolism in adrenoleukodystrophy protein-deficient mice.

Cell Biochemistry and Biophysics 32: 239-246, 2000

2001

81. Matsumoto S, Ohyagi Y, Inoue I, Oishi A, Goto H, Nakagawa T, Yamada T, Kira J:

Periodic alternating nystagmus in a patient with MS.

Neurology 56: 276-277, 2001

82. Tsuruta Y, Furuta A, Furukawa H, Kira J, Iwaki T

Expression of the lysosome-associated membrane proteins in myopathies with rimmed vacuoles.

Acta Neuropath 101: 579-584, 2001

83. Tanaka K, Yamada T, Ohyagi Y, Asahara K, Horiuchi I, Kira J:

Suppression of transthyretin expression by ribozymes: implication for a gene therapy for familial amyloidotic polyneuropathy.

J Neurol Sci 183: 79-84, 2001

84. Osoegawa M, Matsumoto S, Ochi H, Ishiwata K, Nakamura-Uchiyama F, Nawa Y, Yamasaki K, Horiuchi I, Ohyagi Y, Kira J:

Localised myelitis caused by visceral larva migrans due to Ascaris suum masquerading as an isolated spinal cord tumor.


85. Kikuchi H, Osoegawa M, Ochi H, Murai H, Horiuchi I, Takahashi H, Yamabe K, Iwaki T, Mizutani T, Oda M, Kira J:

Spinal cord lesions of myelitis with hyperIgEemia and mite antigen specific IgE (atopic myelitis) manifest eosinophilic inflammation.

J Neurol Sci 183: 73-78, 2001

86. Kira J, Ochi H:

Juvenile muscular atrophy of the distal upper limb (Hirayama disease) associated with atopy.


87. Noerager BD, Inuzuka T, Kira J, Blalock JE, Whitaker JN, Galin FS:

An IgM anti-MBP Ab in a case of Waldenstrom’s macroglobulinemia with polyneuropathy expressing an idiotype reactive with an MBP epitope immunodominant in MS and EAE.

J Neuroimmunol 113: 163-169, 2001

88. Minohara M, Ochi H, Matsushita S, Irie A, Nishimura Y, Kira J:

Differences between T-cell reactivities to major myelin protein-derived peptides in opticospinal and conventional forms of multiple sclerosis and healthy controls.


89. Kira J, Horiuchi I, Suzuki J, Osoegawa M, Tobimatsu S, Murai H, Minohara M, Furue M, Ochi H:

Myelitis associated with atopic disorders in Japan: a retrospective clinical study of the past 20 years.

Intern Med 40: 613-619, 2001

90. Miyoshi Y, Yamada T, Tanimura M, Taniwaki T, Arakawa K, Ohyagi Y, Furuya H, Yamamoto K, Sakai K, Sasazuki T, Kira J:

A novel autosomal dominant spinocerebellar ataxia (SCA16) linked to chromosome 8q22.1 – 24.1.

Neurology 57: 96-100, 2001

91. Yamada T, Minohara M, Imaiso Y, Sakae N, Hara H, Tanaka K, Yamamoto T, Taniwaki T, Furuya H, Kira J:

High dose vitamin C therapy for inclusion body myositis.

Fukuoka Acta Medica 92: 99-104, 2001

92. Ochi H, Wu X-M, Osoegawa M, Horiuchi I, Minohara M, Murai H, Ohyagi Y, Furuya H, Kira J:

Tc1/Tc2 and Th1/Th2 balance in Asian and Western types of multiple sclerosis, HTLV-I-associated myelopathy/tropical spastic paraparesis and hyperIgEaemic myelitis.

J Neuroimmunol 119: 297-305, 2001

93. Horiuchi I, Ochi H, Murai H, Osoegawa M, Minohara M, Furuya H, Kira J:

Th2 shift in mononeuritis multiplex and increase of Th2 cells in chronic inflammatory demyelinating polyneuropathy: an intracellular cytokine analysis.

J Neurol Sci 193: 49-52, 2001

94. Tanaka M, Tanaka K, Tsuji S, Kawata A, Kojima S, Kurokawa T, Kira J, Takiguchi M:

Cytotoxic T cell activity against the peptide, AYRARALEL, from Yo protein of patients with the HLA A24 or B27 supertype and paraneoplastic cerebellar degeneration.

J Neurol Sci 188: 61-65, 2001

95. Suga R, Tobimatsu S, Taniwaki T, Kira J, Kato M:

The soleus late response elicited by transcranial magnetic stimulation reflects agonist-antagonist postural adjustment in lower limbs.


96. Sakae N, Yamada T, Arakawa K, Taniwaki T, Ohyagi Y, Furuya H, Ohnishi A, Kira J:

Adult-onset hereditary sensory and autonomic neuropathy accompanied by anosmia but without skin ulceration.


97. Ogata K, Tobimatsu S, Furuya H, Kira J:

Sporadic amyotrophic lateral sclerosis showing abnormal somatosensory evoked potentials: a report of three cases.

Acta Fukuoka Medica 92: 242-250, 2001

98. Tsuruta Y, Yamada T, Yoshimura T, Satake M, Ogata K, Yamamoto T, Furuya H, Kira J:

Inclusion body myositis associated with hepatitis C virus infection.


2002

99. Itoh K, Naganawa Y, Matsuzawa F, Aikawa S, Doi H, Sasagasako N, Yamada T, Kira J, Kobayashi T, Pshezhetsky AV, Sakuraba H:

Novel missense mutations in human lysosomal sialidase gene causing sialidosis and structural prediction of the mutant enzymes.

J Hum Genet 47: 29-37, 2002

100. Kira J, Osoegawa M, Horiuchi I, Murai H, Minohara M, Ohyagi Y, Furuya H, Tobimatsu S, Ochi H:

History of allergic disorders in common neurologic diseases in Japanese patients.


101. Oishi A, Tobimatsu S, Ochi H, Ohyagi Y, Kubota T, Taniwaki T, Yamamoto T, Furuya H, Kira J:

Paradoxical lateralization of parasagittal spikes revealed by back averaging of EEG and MEG in a case with epilepsia partialis continua.

J Neurol Sci 193: 151-155, 2002

102. Tsuruta Y, Furuta A, Taniguchi N, Yamada T, Kira J, Iwaki T:

Increased expression of manganese superoxide dismutase is associated with that of nitrotyrosine in myopathies with rimmed vacuoles.

Acta Neuropathol (Berl) 103: 59-65, 2002

103. Osoegawa M, Ochi H, Yamada T, Horiuchi I, Murai H, Furuya H, Tobimatsu S, Kira J:

High incidence of subclinical peripheral neuropathy in myelitis with hyperIgEaemia and mite antigen-specific IgE (atopic myelitis): an electrophysiological study.

Intern Med 41: 684-691, 2002

104. Ochi H, Osoegawa M, Wu X-M, Minohara M, Horiuchi I, Murai H, Furuya H, Kira J:

Increased IL-13 but not IL-5 production by CD4-positive T cells and CD8-opsitive T cells in multiple sclerosis during relapse phase.

J Neurol Sci 201: 45-51, 2002

105. Ikezoe K, Nakagawa M, Yan C, Kira J, Goto Y, Nonaka I:

Apoptosis is suspended in muscle of mitochondrial encephalomyopathies.

Acta Neuropathol (Berl) 103: 531-540, 2002

106. Matsumura K, Antoku Y, Inoue R, Kobayashi M, Hanada E, Iwasaki Y, Kumagai Y, Iwamoto H, Tsuchihashi S, Iwaki M, Kira J, Nose Y:A network system of medical and welfare information service for the patients, their families, hospitals, local governments, and commercial companies in a medical service area.J Med Syst 26: 249-254, 2002

107. Taniwaki T, Nakagawa M, Yamada T, Yoshida T, Ohyagi Y, Sasaki M, Kuwabara Y, Tobimatsu S, Kira J:

Cerebral metabolic changes in early multiple system atrophy: a PET study.

J Neurol Sci 200: 79-84, 2002

108. Ochi H, Horiuchi I, Araki N, Toda T, Araki T, Sato K, Murai H, Osoegawa M, Yamada T, Okamura K, Ogino T, Mizumoto K, Yamashita H, Saya H, Kira J:

Proteomic analysis of human brain identifies alpha-enolase as a novel autoantigen in Hashimoto's encephalopathy.

FEBS Lett 528: 197-202, 2002

109. Shigeto H, Morioka T, Hisada K, Nishio S, Ishibashi H, Kira J, Tobimatsu S, Kato M:

Feasibility and limitations of magnetoencephalographic detection of epileptic discharges: simultaneous recording of magnetic fields and electrocorticography.

Neurol Res 24: 531-536, 2002

2003

110. Arakawa K, Tomi H, Tobimatsu S, Kira J:

Middle latency auditory evoked potentials in myotonic dystrophy: relation to the size of the CTG trinucleotide repeat and intelligent quotient.

J Neurol Sci 207: 31-36, 2003

111. Osoegawa M, Ochi H, Kikuchi H, Shirabe S, Nagashima T, Tsumoto T, Tamura Y, Yamabe K, Takahashi H, Iwaki T, Kira J:

Eosinophilic myelitis associated with atopic diathesis: a combined neuroimaging and histologic study.


112. Osoegawa M, Ochi H, Minohara M, Murai H, Umehara F, Furuya H, Yamada T, Kira J:

Myelitis with atopic diathesis: a nationwide survey of 79 cases in Japan.

J Neurol Sci 209：5-11,　2003

113. Furuya H, Yasuda M, Terasawa K, Tanaka K, Murai H, Kira J, Ohyagi H:

A novel mutation (L250V) in the presenilin 1 gene in a Japanese familial Alzheimer’s disease with myoclonus and generalized convulsion.

J Neurol Sci 209: 75-77, 2003

114. Kikuchi H, Yamada T, Furuya H, Doh-ura K, Ohyagi Y, Iwaki T, Kira J:

Involvement of cathepsin B in the motor neuron degeneration of amyotrophic lateral sclerosis.


115. Ikezoe K, Furuya H, Ohyagi Y, Osoegawa M, Nishino I, Nonaka I, Kira J:

Dysferlin expression in tubular aggregates: their possible relationship to the ER stress.


116. Taniwaki T, Okayama A, Yoshiura T, Nakamura H, Goto Y, Kira J, Tobimatsu S:

Reappraisal of the motor role of basal ganglia: An fMRI study.

J Neurosci 23: 3432-3438, 2003

117. Hattori N, Yamamoto M, Yoshihara T, Koike H, Nakagawa M, Yoshikawa H, Ohnishi A, Hayasaka K, Onodera O, Baba M, Yasuda H, Saito T, Nakashima K, Kira J, Kaji R, Oka N, Sobue G:

Demyelinating and axonal features of Charcot-Marie-Tooth disease with mutations of myelin-related proteins (PMP22, MPZ and Cx32): a clinicopathological study of 205 Japanese patients.

Brain 126: 134-151, 2003

118. Ochi H, Murai H, Osoegawa M, Minohara M, Inaba S, Kira J:

Juvenile muscular atrophy of distal upper extremity associated with airway allergy: two cases successfully treated by plasma exchange.

J Neurol Sci 206: 109-114, 2003

2004

119. Tokunaga H, Osoegawa M, Murai H, Ochi H, Minohara M, Taniwaki T, Kira J:

Anterior horn cell involvement in myelitis with atopic diathesis (atopic myelitis).

Fukuoka Acta Media 95: 36-43, 2004

120. Ikezoe K, Nakagawa M, Osoegawa M, Kira J, Nonaka I:

Ultrastructural detection of DNA fragmentation in myonuclei of fatal reducing body myopathy.


121. Osoegawa M, Niino M, Ochi H, Kikuchi S, Murai H, Fukazawa T, Minohara M, Tashiro K, Kira J:

Platelet-activating factor acetylhydrolase gene polymorphism and its activity in Japanese patients with multiple sclerosis.

J Neuroimmunol 150: 150-156, 2004

122. Yamada T, Ohyagi Y,Shinnoh N, Kikuchi H, Osoegawa M, Ochi H, Kira J, Furuya H:

Therapeutic effects of normal cells on ABCD1 deficient cells in vitro and hematopoietic cell transplantation in the X-ALD mouse model.

J Neurol Sci 218: 91-97, 2004

123. Murakami-Kubo I, Doh-Ura K, Ishikawa K, Kawatake S, Sasaki K, Kira J, Ohta S, Iwaki T:

Quinoline derivatives are therapeutic candidates for transmissible spongiform encephalopathies.

J Virol 78: 1281-1288, 2004

124. Ochi H, Osoegawa M, Murai H, Wu X-M, Taniwaki T, Kira J:

Presence of IgE antibodies to bacterial superantigens and increased IL-13-producing T cells in myelitis with atopic diathesis.

Int Arch Allergy Immunol 134: 41-48, 2004

125. Ochi H, Mei F-J, Osoegawa M, Minohara M, Murai H, Taniwaki T, Kira J:

Time-dependent cytokine deviation toward the Th2 side in Japanese multiple sclerosis patients with interferon beta-1b.

J Neurol Sci 222: 65-73, 2004

126. Yamasaki T, Taniwaki T, Tobimatsu S, Arakawa K, Kuba H, Maeda Y, Kuwabara Y, Shida K, Ohyagi Y, Yamada T, Kira J:

Electrophysiological correlates of associative visual agnosia lesioned in the ventral pathway.

J Neurol Sci 221: 53-60, 2004

127. Murai H, Osoegawa M, Ochi H, Kira J:

High frequency of allergic conjunctivitis in myasthenia gravis without thymoma.

J Neurol Sci 225: 27-31, 2004

128. Murai H, Arahata H, Osoegawa M , Ochi H, Minohara M, Taniwaki T, Tobimatsu S, Mihara F, Tsuruta Y, Inaba S, Kira J:

Effect of immunotherapy in myelitis with atopic diathesis.

J Neurol Sci 227: 39-47, 2004

2005

129. Osoegawa M , Ochi H, Mei F-J, Minohara M, Murai H, Taniwaki T, Kira J:

Th2 shift in juvenile muscular atrophy of distal upper extremity: a combined allergological and flow cytometric analysis.

J Neurol Sci 228: 87-92, 2005

130. Ohyagi Y, Asahara H, Chui D-H, Tsuruta Y, Miyoshi K, Sakae N, Yamada T, Kikuchi H, Ikezoe K, Taniwaki T, Murai H, Furuya H, Shoji M, Kawarabayashi T, Checler F, Iwaki T, Makifuchi T, Takeda K, Kira J, Tabira T:

Intracellular Aβ42 activates p53 promoter: a pathway to neurodegeneration in Alzheimer’s disease.FASEB J 19: 255-257, 2005

131. Mei F-J, Ishizu T, Murai H, Osoegawa M, Minohara M, Zhang K-N, Kira J:

Th1 shift in CIDP versus Th2 shift in vasculitic neuropathy in CSF.

J Neurol Sci 228: 75-85, 2005

132. Yamasaki T, Goto Y, Taniwaki T, Kira J, Tobimatsu S:

Left hemisphere specialization for rapid temporal processing: a study with auditory 40Hz steady-state responses.


133. Furuya H, Shinnoh N, Ohyagi Y, Ikezoe K, Kikuchi H, Osoegawa M, Fukumaki Y,

Nakabeppu Y, Hayashi T, Kira J:

Some flavonoids and DHEA-S prevent the cis-effect of expanded CTG repeats in a stable PC12 cell transformant.

Biochem Pharmacol 69: 503-516, 2005

134. Ishizu T, Osoegawa M, Mei F-J, Kikuchi H, Tanaka M, Takakura Y, Minohara M, Murai H, Mihara F, Taniwaki T, Kira J:

Intrathecal activation of the IL-7/IL-8 axis in opticospinal multiple sclerosis.

Brain 128: 988-1002, 2005

135. Furuya H, Yamada T, Ohyagi Y, Ikezoe K, Miyoshi Y, Fujii N, Kira J:

Neurological signs and symptoms in patients with chronic PCB poisoning (Yusho accident) for more than 36 years.

J Dermatol Sci Suppl 1: S39-S44, 2005.

136. Osoegawa M, Miyagishi R, Ochi H, Nakamura I, Niino M, Kikuchi S, Murai H, Fukazawa T, Minohara M, Tashiro K, Kira J:

Platelet-activating factor receptor gene polymorphism in Japanese patients with multiple sclerosis.

J Neuroimmunol 161: 195-198, 2005

137. Nakagawa M, Kuwabata Y, Taniwaki T, Sasaki M, Koga H, Kaneko K, Hayashi K, Kira J Honda H:

PET evaluation of the relationship between D2 receptor binding and glucose metabolism in patients with parkinsonism.

Ann Nucl Med 19: 267-275, 2005

138. Oishi A, Tobimatsu S, Arakawa K, Taniwaki T, Kira J:

Ocular dominancy in conjugate eye movements at reading distance.

Neurosicence Research 52: 263-268, 2005

139. Osoegawa M, Niino M, Tanaka M, Kikuchi S, Murai H, Fukazawa T, Minohara M, Miyagishi R, Taniwaki T, Tashiro K, Kira J:

Comparison of the clinical course of opticospinal and conventional forms of multiple sclerosis in Japan.

Intern Med 44: 934-938, 2005

140. Furuya H, Yamada T, Murai H, Ikezoe K, Ohyagi Y, Matsumoto T, Miyoshi Y, Fujii N, Kira J:

Usefulness of manual muscle testing of pronator teres and supinator muscles in assessing cervical radiculopathy.

Fukuoka Acta Med 96: 319-325, 2005

141. Koike H, Hirayama M, Yamamoto M, Ito H, Hattori N, Umehara F, Arimura K, Ikeda S, Ando Y, Nakazato M, Kaji R, Hayasaka K, Nakagawa M, Sakoda S, Matsumura K, Onodera O, Baba M, Yasuda H, Saito T, Kira J, Nakashima K, Oka N, Sobue G:

Age associated axonal features in HNPP with 17p11.2 deletion in Japan.


142. Iijima M, Yamamoto M, Hirayama M, Tanaka F, Katsuno M, Mori K, Koike H, Hattori N, Arimura K, Nakagawa M, Yoshikawa H, Hayasaka K, Onodera O, Baba M, Yasuda H, Saito T, Nakazato M, Nakashima K, Kira J, Kaji R, Oka N, Sobue G:

Clinical and electrophysiologic correlates of IVIg responsiveness in CIDP.

Neurology 64: 1471-1475, 2005

2006

143. Su J-J, Osoegawa M, Minohara M, Tanaka M, Ishizu T, Mihara F, Taniwaki T, Kira J:

Upregulation of vascular grouth factors in multiple sclerosis: correlation with MRI findings.

J Neurol Sci 243: 21-30, 2006

144. Mei F-J, Osoegawa M, Ochi H, Minohara M, Shi N, Murai H, Ishizu T, Taniwaki T, Kira J:

Long-term favorable response to interferon beta-1b is linked to cytokine deviation toward the Th2 and Tc2 sides in Japanese patients with multiple sclerosis.

J Neurol Sci 246: 71-77, 2006

145. Yokomine K, Nakatsura T, Minohara M, Kira J, Kubo T, Sasaki Y, Nishimura Y:

Immunization with heat shock protein 105-pulsed dentritic cells leads to tumor rejection in mice.

Biochem Biophys Res Comm 343: 269-278, 2006

146. Ishizu T, Minohara M, Ichiyama T, Kira R, Tanaka M, Osoegawa M, Hara T, Furukawa S, Kira J:

CSF cytokine and chemokine profiles in acute disseminated encephalomyelitis.


147. Tashiro K, Kikuchi S, Itoyama Y, Tokumaru Y, Sobue G, Murai E, Akiguchi I, Nakashima K, Kira J, Hirayama K:

Nationwide survey of juvenile muscular atrophy of distal upper extremity (Hirayama disease) in Japan.

Amyotrophic Lateral Sclerosis 7: 38-45, 2006

148. Ikezoe K, Ohshima S, Osoegawa M, Ogawa K, Nagata K, Kira J:

Expression of granulysin in infiltrating cells in polymyositis and inclusion body myositis: its possible relationship to steroid resistance in polymyositis.


149. Minohara M, Matsuoka T, Li W, Osoegawa M, Ishizu T, Ohyagi Y, Kira J:

Upregulation of myeloperoxidase in patients with opticospinal multiple sclerosis: positive correlation with disease severity.

J Neuroimmunol 178: 156-160, 2006

150. Tanaka M, Kikuchi H, Ishizu T, Minohara M, Osoegawa M, Motomura K, Tateishi T,

Ohyagi Y, Kira J:

Intrathecal upregulation of G-CSF and its neuroprotective actions on motor neurons in amyotrophic lateral sclerosis.

J Neuropathol Exp Neurol 65: 816-825, 2006

151. Taniwaki T, Okayama A, Yoshima T, Nakayama Y, Yamasaki T, Igata K, Kira J,

Tobimatsu S:

Functional network of the basal ganglia and cerebellar motor loops in vivo: different activation patterns between self-initiated and externally-triggered movements.

NeuroImage 31: 745-753, 2006

152. Miura S, Shibata H, Furuya H, Ohyagi Y, Osoegawa M, Miyoshi Y, Matsunaga H, Shibata A, Matsumoto N, Iwaki A, Taniwaki T, Yamada T, Kikuchi H, Kira J, Fukumaki Y:

The contactin 4 gene locus at 3p26 is a candidate gene of SCA16.

Neurology 67: 1236-1241, 2006

153. Sun X, Minohara M, Kikuchi S, Ishizu T, Tanaka M, Piao H, Osoegawa M, Ohyagi Y, Shimokawa H, Kira J:

The selective Rho-kinase inhibitor Fasudil is protective and therapeutic in experimental allergic encephalomyelitis.

J Neuroimmunol 180: 126-134, 2006

154. Tashiro K, Ogata K, Goto Y, Taniwaki T, Okayama A, Kira J, Tobimatsu S:

EEG findings in early-stage corticobasal degeneration and progressive supranuclear palsy: A retrospective study and literature review.


2007

155. Ohyagi Y, Tsuruta Y, Motomura K, Miyoshi K, Kikuchi H, Iwaki T, Taniwaki T, Kira J:

Intraneuronal amyloid β42 enhanced by heating but counteracted by formic acid.

J Neurosci Meth 159: 134-138, 2007

156. Shi N, Kawano Y, Tateishi T, Kikuchi H, Osoegawa M, Ohyagi Y, Kira J:

Increased IL-13-producing T cells in ALS: positive correlations with disease severity and progression rate.

J Neuroimmunol 182: 232-235, 2007

157. Li W, Minohara M, Su JJ, Matsuoka T, Osoegawa M, Ishizu T, Kira J:

Helicobacter pylori infection is a potential protective factor against conventional multiple sclerosis in the Japanese population.

J Neuroimmunol 184: 227-231, 2007

158. Pineda AAM, Ogata K, Osoegawa M, Murai H, Shigeto H, Tobimatsu S, Kira J:

A distinct subgroup of chronic inflammatory demyelinating disease with CNS demyelination and a favorable response to immunotherapy.

J Neurol Sci 255: 1-6, 2007

159. Matsuoka T, Matsushita T, Kawano Y, Osoegawa M, Ochi H, Ishizu T, Minohara M, Kikuchi H, Mihara F, Ohyagi Y, Kira J:

Heterogeneity of aquaporin-4 autoimmunity and spinal cord lesions in multiple sclerosis in Japanese.

Brain 130: 1206-1223, 2007

160. Arimura K, Nakagawa M, Izumo S, Usuku K, Itoyama Y, Kira J, Osame M:

Safety and efficacy of interferon-a in 167 patients with human T-cell lymphotropic virus type 1-associated myelopathy.

J Neurovirol 13: 364-372, 2007

161. Kurokawa-Kuroda T, Ogata K, Suga R, Goto Y, Taniwaki T, Kira J, Tobimatsu S:

Altered soleus responses to magnetic stimulation in pure cerebellar ataxia.

Clin Neruophysiol 118: 1198-1203, 2007

162. Taniwaki T, Okayama A, Yoshiura T, Togao O, Nakamura Y, Ogata K, Shigeto H, Ohyagi Y, Kira J, Tobimatsu S:

Age-related alterations of the functional interactions within the basal ganglia and cerebellar motor loops in vivo.

Neuroimage 36: 1263-1276, 2007

163. Yamasaki R, Zhang J, Koshiishi I, Sastradipura-Suniarti DF, Wu Z, Peters C, Schwake M, Uchiyama Y, Kira J, Saftig P, Utsumi H, Nakanishi H:

Involvement of lysosomal storage-induced p38 MAP kinase activation in the overproduction of nitric oxide by microglia in cathepsin D-deficient mice.

Mol Cell Neurosci 35: 573-584, 2007

164. Tashiro K, Ogata K, Yamasaki T, Kuroda T, Goto Y, Munetsima S, Kinukawa N, Kira J, Tobimatsu S:

Repetitive transcranial magnetic stimulation alters optic flow perception.

Neuroreport 18: 229-233, 2007

165. Ikezoe K, Nakamori M, Furuya H, Arahata H, Kanemoto S, Kimura T, Imaizumi K, Takahashi M, Sakoda S, Fujii N, Kira J:

Endoplasmic reticulum stress in myotonic dystrophy type 1 muscle.

Acta Neuropathologica 114: 527-535, 2007

166. Yokomine K, Nakatsura T, Senju S, Nakagata N, Minohara M, Kira J, Motomura Y, KuboT, Sasaki Y, Nishimura Y:

Regression of intestinal adenomas by vaccination with heat shock protein 105-pulsed bone marrow-derived dendritic cells in ApcMin/+mice.

Cancer Science 98: 1930-1935, 2007

2008

167. Matsushita T, Matsuoka T, Ishizu T, Kikuchi H, Osoegawa M, Kawano Y, Mihara F, Ohyagi Y, Kira J:Anterior periventricular linear lesions in optic-spinal multiple sclerosis: a combined neuroimaging and neuropathological study.Multiple Sclerosis 14: 343-353, 2008

168. Matsuoka T, Matsushita T, Osoegawa M, Ochi H, Kawano Y, Mihara F, Ohyagi Y, Kira JHeterogeneity and continuum of multiple sclerosis in Japanese according to magnetic resonance imaging findings.J Neurol Sci 266: 115-125, 2008

169. Furuya H, Ikezoe K, Wang L, Ohyagi Y, Motomura K, Fuji N, Kira J, Fukumaki Y:A unique case of fibrodysplasia ossificans progressiva with an ACVR1 mutation, G 356D, other than the common mutation (R 206H).Am J Med Genet 146A(4):459-463, 2008

170. Iwaki A, Kawano Y, Miura S, Shibata H, Matsuse D, Li W, Furuya H, Ohyagi Y, Taniwaki T, Kira J, Fukumaki Y:Heterozygous deletion of ITPRI, but not SUMF1 in spinocerebellar ataxia type 16.J Med Genet 45: 32-35, 2008

171. Kawajiri M, Mogi M, Osoegawa M, Matsuoka T, Tsukada K, Kohara K, Horiuchi M, Miki T, Kira J:Reduction of angiotensin Ⅱ in the cerebrospinal fluid of patients with multiple sclerosis.Multiple Sclerosis 14: 557-560, 2008

172. Kira J,* Isobe N,* Kawano Y, Osoegawa M, Ohyagi Y, Mihara F, Murai H:Atopic myelitis with focal amyotrophy: a possible link to Hopkins syndrome.J Neurol Sci 269: 143-51, 2008*Equal contribution.

173. Takase K, Shigeto H, Suzuki S, Kikuchi H, Ohyagi Y, Kira J:Prenatal freeze lesioning produces epileptogenic focal cortical dysplasia.Epilepsia 49: 997-1010, 2008

174. Matsuoka T, Matsushita T, Osoegawa M, Kawano Y, Minohara M, Mihara F, Nishimura Y, Ohyagi Y, Kira J:Association of the HLA-DRB1 alleles with characteristic MRI features of Asian multiple sclerosis.Multiple Sclerosis 14: 1181-1190, 2008

175. Tanaka M, Matsushita T, Tateishi T, Ochi H, Kawano Y, Mei F-J, Minohara M, Murai H, Kira J:Distinct CSF cytokine/chemokine profiles in atopic myelitis and other causes of myelitis.Neurology 71: 974-981, 2008

176. Sakae N, Yamasaki N, Kitaichi K, Fukuda T, Yamada M, Yoshikawa H, Hiranita T, Tatsumi Y, Kira J, Yamamoto T, Miyakawa T, Nakayama K:Mice lacking the schizophrenia-associated protein FEZ1 manifest by hyperactivity and enhanced responsiveness to psychostimulants. Hum Mol Genet 3191-3203, 2008

177. Tanaka M*, Ishizu T*, Ochi H, Kawano Y, Ohyagi Y, Kira J:Intrathecal upregulation of IFN-γ and MIP-Iβ in juvenile muscular atrophy of the distal upper axtremity.J Neurol Sci 275: 74-77, 2008*Equal contribution

178. Hirata K, Kanemaru T, Minohara M, Togo A, Kira J:Accumulation of stress-related proteins with the glomeruli of the rat olfactory bulb following damage to olfatory receptor neurons.Arch Histol Cytol 71: 265-277, 2008.

179. Oishi A, Tobimatsu S, Ogata K, Taniwaki T, Kinukawa N, Toyoshiba H, Kira J:Differential contributions of spinal and cortical motoneurons to input-output properties of human small hand muscleNeurol Res 30: 1106-1113, 2008

2009

180. Takase K, Shigeto H, Suzuki S, Kikuchi H, Ohyagi Y, Kira J:

Cortical kindling in a focal freeze lesion rat model.

Journal of Clinical Neuroscience 16: 94-98, 2009

181. Shi N, Kawano Y, Matsuoka T, Mei F-J, Ishizu T, Ohyagi Y, Kira J:

Increase of CD4+ TNFα+ IL-2- T cells in cerebrospinal fluid of multiple sclerosis patients.

Multiple Sclerosis 15: 120-123, 2009

182. Kawajiri M, Mogi M, Higaki N, Tateishi T, Ohyagi Y, Horiuchi M, Miki T, Kira J:

Reduced angiotensin II levels in the cerebrospinal fluid of patients with amyotrophic lateral sclerosis. Acta Neurol Scand 119: 341-344, 2009

183. Kawajiri M, Mogi M, Higaki N, Matsuoka T, Ohyagi Y, Tsukada K, Kahara K, Horiuchi M, Miki T, Kira J:Angiotensin-converting anzyme (ACE) and ACE2 levels in the cerebrospinal fluid of patients with multiple sclerosis. Multiple Sclerosis 15: 262-265, 2009

184. Osoegawa M*, Kira J*, Fukazawa K, Kikuchi S, Kohriyama T, Sobue G, Yamamura T, Itoyama Y, Saida T, Sakata K, Ochi H, Matsuoka T: Temporal changes and geographical differences in multiple sclerosis phenotypes in Japanese: nationwide survey results over 30 years.Multiple Sclerosis 15: 159-173, 2009*Equal contribution

185. Ohshima S, Shin J, Yuasa K, Nishiyama A, Kira J, Okada T, Takeda S:Transduction efficiency and immune response associated with the administration of AAV8.Molecular Therapy 17: 73-80, 2009

186. Ma L, Ohyagi Y, Miyoshi K, Sakae N, Motomura K, Taniwaki T, Furuya H, Takeda K, Tabira T, Kira J:Increase in p53 Protein Levels by Presenilin 1 Gene Mutations and its Inhibitors. Journal of Alzheimer's disease 16: 565-575, 2009

187. Doi H, Matsushita T, Isobe N, Matsuoka T, Minohara M, Ochi H, Kira J:Hypercomplementemia at relapse in patients with anti-aquaporin-4 antibody.Multiple Sclerosis 15: 304-310, 2009

188. Miyoshi K, Ohyagi Y, Motomura K, Ma L, Sakae N, Kikuchi H, Taniwaki T, Furuya H, Tabira T, Kira J: Enhancement of activation of caspases by presenilin 1 gene mutations and its inhibition by secretase inhibitors.Journal of Alzheimer’s disease 16: 551-564, 2009

189. Matsushita T, Matsuoka T, Isobe N, Kawamura Y, Minohara M, Shi N, Nishimura Y, Ochi H, Kira J: Association of the HLADPB1*0501 allele with anti-aquaporin-4 antibody positivity in Japanese patients with idiopathic central nervous system demyelinating disorders.Tissue Antigens 72: 171-176, 2009

190. Takakura Y, Yamaguchi N, Satoh K, Kira J, Nishida N:Bone marrow stroma cells are susceptible to prion infection.Biochem Biophys Res Commun 377: 957-961, 2009

191. Ishizu T*, Kira J*, Osoegawa M, Fukazawa T, Kikuchi S, Fujihara K, Matsui M, Kohriyama T, Sobue G, Yamamura T, Itoyama Y, Saida T, Sakata K:Heterogeneity and continuum of multiple sclerosis phenotypes in Japanese according to the results of the fourth nationwide survey.J Neurol Sci 280: 22-28, 2009* equal contribution

192. Ikezoe K, Furuya H, Arahata H, Nakagawa M, Tateishi T, Fujii N, Kira J:Amyloid-B accumulation caused by chloroquine injections produces ER stress and autophagosome formation in rat skeletal muscle.Acta Neuropathol 117: 575-582, 2009

193. Matsumoto S, Nakahara I, Higashi T, Iwamoto Y, Watanabe Y, Takahashi K, Ando M, Takezawa M, Kira J:Near-infrared soectroscopy in carotid artery stenting predicts cerebral hyperpefusion syndrome.Neurology 72: 1512-1518, 2009

194. Doi H, Matsushita T, Isobe N, Ishizu T, Ohyagi Y, Kira J:Frequency of chronic headaches in Japanese patients with multiple sclerosis with special reference to opticospinal and common forms of multiple sclerosis.Headache 49: 1513-1520, 2009

195. Matsushita T, Isobe N, Matsuoka T, Shi N, Kawano Y, Wu X-M, Yoshiura T, Nakao Y, Ishizu T, Kira J:Aquaporin-4 autoimmune syndrome and anti-aquaporin-4 antibody-negative optico spinal multiple sclerosis in Japanese.Multiple Sclerosis 15: 834-847, 2009

196. Watanabe A*, Matsushita T*, Doi H, Matsuoka T, Shigeto H, Isobe N, Kawano Y, Tobimatsu S, Kira J:Multimodality evoked potential study of anti-aquaporin-4 antibody-positive and –negative multiple sclerosis patients.J Neurol Sci 281: 34-40, 2009 *equal contribution

197. Matsushita T, Isobe N, Matsuoka T, Ishizu T, Kawano Y, Yoshiura T, Ohyagi Y, Kira J:Extensive vasogenic edema of anti-aquaporin-4 antibody-related brain lesions.Mult Scler 15: 790-797, 2009

198. Isobe N, Kira J, Kawamura N, Ishizu T, Arimura K, Kawano Y: Neural damage associated with atopic diathesis: a nationwide survey in Japan.Neurology 73: 790-797, 2009

199. Li W, Minohara M, Piao H, Matsushita T, Masaki K, Matsuoka T, Isobe N, Su JJ, Ohyagi Y, Kira J:Association of anti-Helicobacter pylori neutrophil-activating protein antibody response with anti-aquaporin-4 autoimmunity in Japanese patients with multiple sclerosis and neuromyelitis optica.Multiple Sclerosis 15: 14111-1421, 2009

200. Murai H, Uchiyama A, Mei F-J, Kojima M, Kira J:Long-term effects of infrasternal mediastinoscopic thymectomy in myasthenia gravis.J Neurol Sci 287: 185-187, 2009

201. Wu XM, Wang C, Zhang KN, Lin AY, Kira J, Hu GZ, Qu XH, Xiong YQ, Cao WF, Gong LY:Association of susceptibility to multiple sclerosis in Southern Han Chinese with HLA-DRB1, -DPB1 alleles and DRB1-DPB1 haplotypes: distinct from other populations.Multiple Sclerosis 15: 1422-1430, 2009

202. Takase K, Shigeto H, Kamada T, Ohyagi Y, Kira J:Efficacy of mediodorsal thalamic nucleus stimulation in a rat model of cortical seizure.Fukuoka Acta Medica 100: 274-280, 2009

203. Kihara Y, Matsushita T, Kita Y, Uematsu S, Akira S, Kira J, Ishii S, Shimizu T:Targeted lipidomics reveals mPGES-1-PGE2 as a therapeutic target for multiple sclerosis.Proc Natt Acad Sci USA 106: 21807-21812, 2009

2010

204. Okada K, Matsushita T, Kira J: Tsui S:B-cell activating factor of the TNF family is up-regulated in neuromyelitis optica.Neurology 74: 177-178, 2010

205. Ueda M*, Kawamura N*, Tateishi T, Motomura K, Sakae N, Ohyagi Y, Kira J:Phenotypic prectrum of hereditary brachial plexus neuropathy caused by the SEPT9 R88W mutation.J Neurol Neurosurg Psychiatry 81: 94-96, 2010* equal contribution

206. Piao H*, Minohara M*, Kawamura N, Li W, Mizunoe Y, Umehara F, Goto Y, Kusunoki S, Matsushita T, Ikenaka K, Maejima T, Nabekura J, Yamasaki R, Kira J:Induction of paranodal myelin detachment and sodium channel loss in vivo by Campylobacter jejuni DNA-binding protein from starved cells (C-Dps) in myelinated nerve fibers.J Neurol Sci 288: 54-62, 2010*Both authors contributed equally

207. Qiu W, Wu JS, Zhang MN, Matsushita T, Kira J, Carroll WM, Mastaglia L, Kermode AG:Longitudinally extensive myelopathy in Caucasians: a West Australian study of 26 cases from the Perth Demyelinating Diseases Database.J Neurol Neurosurgery Psychiatry 81: 209-212, 2010

208. Tateishi T, Hokonohara T, Yamasaki R, Miura S, Kikuchi H, Iwaki A, Tashiro H, Furuya H, Nagara Y, Ohyagi Y, Nukina N, Iwaki T, Fukumaki Y, Kira J:Multiple system degeneration with basophilic inclusions in Japanese ALS patients with FUS mutation.Acta Neuropathol 119: 355-364, 2010

209. Matsumoto S, Nakahara I, Higashi T, Iwamuro Y, Watanabe Y, Takezawa M, Murata D, Yokota T, Kira J, Yamada T: Fibro-fatty volume of culprit lesions by virtual HistologyTM intravascular ultrasound is associated with the amount of debris during carotid artery stenting.Cerebrovascular Diseases 29: 468-475, 2010

210. Matsushita T, Isobe N, Piao H, Matsuoka T, Ishizu T, Doi H, Masaki K, Yoshimura T, Yamasaki R, Ohyagi Y, Kira J: Reappraisal of brain MRI features in multiple sclerosis and neuromyelitis optica patients according to anti-aquaporin-4 antibody status.J Neurol Sci 291: 37-43, 2010

211. Hagiwara K, Okamoto T, Shigeto H, Ogata K, Somehara Y, Matsushita T, Kira J, Tobimatsu S:Oscillatory gamma synchronization binds the primary and secondary somatosensory areas in humans.Neuroimage 51: 412-420, 2010

212. Isobe N, Matsushita T, Yamasaki R, Ramagopalan SV, Kawano Y, Nishimura Y, Ebers GC, Kira J:Influence of HLA-DRB1 alleles on the susceptibility and resistance to multiple sclerosis in Japanese patients with respect to anti-aquaporin 4 antibody status.Multiple Sclerosis 16: 147-155, 2010

213. Tateishi T, Yamasaki R, Tanaka M, Matsushita T, Kikuchi H,　Isobe N, Ohyagi Y, Kira J:CSF chemokine alterations related to the clinical course of amyotrophic lateral sclerosis.Journal of Neuroimmunology 222: 76-81, 2010

214. Kai N, Kawajiri M, Seki N, Tanaka N, Kira J, Tobimatsu S, Naito S:Efficiancy of high-frequency magnetic stimulation of the sacral root in patients with urinary in continence following a nadical prostatectomy.LUTS 3: 10-14, 2010

215. Matsushita T, Isobe N, Kawajiri M, Mogi M, Tsukada K, Horiuchi M, Yamasaki R, Ohyagi Y, Kira J:CSF angiotensin II and angiotensin-converting enzyme levels in anti-aquaporin-4 autoimmunity.J Neurol Sci 295: 41-45, 2010

216. Yoshimura S, Ochi H, Isobe N, Matsushita T, Motomura K, Matsuoka T, Minohara M, Kira J:Altered production of brain-derived neurotrophic factor by peripheral blood immune cells in multiple sclerosis.Mult Scler 16: 1178-1188, 2010

217. Matsuse D, Kitada M, Kohama M, Nishikawa K, Makinoshima H, Wakao S, Fujiyoshi Y, Heike T, Nakahata T, Akutsu H, Umezawa A, Harigae H, Kira J, Dezawa M:Human umbilical cord-derived mesenchymal stromal cells differentiate into functional Schwann cells that sustain peripheral nerve regeneration.J Neuropathol Exp Neurol 69: 973-985, 2010

218. Yamasaki R, Tanaka M, Fukunaga M, Tateishi T, Kikuchi H, Motomura K, Matsushita T, Ohyagi Y, Kira J:Restoration of microglial function by granulocyte-colony stimulating factor in ALS model mice.J Neuroimmnol 229: 51-62, 2010

219. Piero P, Longo MR, Scalia F, Polosa R, Kira J, Falsaperla R:Recurrent Hopkins syndrome: a case report and review of the literature.J Neurol Sci 297: 89-91, 2010

220. Matsuoka T, Suzuki SO, Iwaki T, Tabira T, Ordinario AT, Kira J:Aquaporin-4 astrocytopathy in Balo's disease.Acta Neuropathol 120: 651-660, 2010

2011

221. Kikuchi H, Mifune N, Niino M, Ohbu S, Kira J, Kohriyama T, Ota K, Tanaka M, Ochi H, Nakane S, Maezawa M, Kikuchi S:Impact and characteristics of quality of life in Japanese patients with multiple sclerosi.Qual Life Res 20: 119-131, 2011

222. Piao H, Minohara M, Kawamura N, Li W, Matsushita T, Yamasaki R, Mizunoe Y, Kira J:Tissue binding patterns and in vitro effects of Campylobacter jejuni DNA-binding protein form starved cells.Neurochem Res 36: 58-66, 2011.

223. Ohshima S, Tsuboi Y, Yamamoto A, Kawakami M, Farrer MJ, Kira J, Shii H:Autonomic failures in Pery syndrome with DCTN1 mutation.Parkinsonism Relat Disord 16: 612-614, 2010

224. Himeno E, Ohyagi Y, Ma L, Nakamura N, Miyoshi K, Sakae N, Motomura K, Soejima N, Yamasaki R, Hashimoto T, Tabira T, LaFerla FM, Kira J:Apomorphine treatment for Alzheimer's mice promoting amyloid-β degradation.Ann Neurol 69: 248-256, 2011.

225. Doi H, Matsushita T, Isobe N, Tateishi T, Kira J:Analysis of cerebrospinal fluid cytokines and growth factors in multiple sclerosis patients with and without chronic headaches.Neurology Asia 16: 65-70, 2011

226. Kawamura N＊, Pia H＊, Minohara M, Matsushita T, Kusunoki S, Matsumoto H, Ikenaka K, Mizunoe Y, Kira J;

Campylobacter jejuni DNA-binding protein from starved cells in Guillain-Barré syndrome.

J Neuroimmunol 240-241: 74-78, 2011

＊Both contributed equally.

227. Yoshiura T, Hiwatashi A, Yamashita K, Ohyagi Y, Monji A, Takayama Y, Kamano N, Kawashima T, Kira J, Honda H: Deterioration of abstract reasoning ability in mild cognitive impairment and Alzheimer’s disease: correlation with regional grey matter volume loss revealed by diffeomorphic anatomical registration through exponentiated lie algebra analysis. Eur Radiol 21: 419-425, 2010

228. Matsuoka T, Suzuki SO, Suenaga T, Iwaki T, Kira J:Reappresal of aquaporin-4 astrocytopathy in Asian neuromyelitis optica and multiple sclerosis patients. Brain Pathol 21: 516-532, 2011

229. Murai H, Yamashita N, Watanabe M, Nomura Y, Motomura , Yoshikawa H, Kawaguchi N, Onodera H, Araga S, Isobe N, Nakamura Y, Nagai M, Kira j:

Characteristics of myasthenia gravis according to onset-age: third Japanese nationwide survey.

J Neurol Sci 305: 97-102, 2011

230.Fang L*, Isobe N*, Yoshimura S, Yonekawa T, Matsushita T, Masaki K, Doi H, Ochi K, Miyamoto K, Kawano Y, Kira J:

Interleukin-7 receptor alpha gene polymorphism influences multiple sclerosis risk in Asians.

Neurology 76: 2125-2127, 2011.

*Equal contribution.

231.Pineda AAM＊, Minohara M＊, Kawamura N, Matsushita T, Yamasaki R, Sun X, Piao H, Shimokawa H, KiraJ:

Preventive and therapeutic effects of the selective Rho-kinase inhibitor fasudil on experimental autoimmune neuritis.

J Neurol Sci 306: 115-120, 2011

*Equal contribution.

232. Matsuse D, Kitada M, Ogura F, Wakao S, Kohama M, Kira J, Tabata Y, Dezawa M:

Combined transplantation of bone marrow stroma cell-derived neural progenitor cells with a collagen sponge and fibroblast growth factor (bFGF) releasing microspheres enhances recovery after cerebral ischemia in rats.

Tissue Engineering 17: 1993-2004, 2011.

233. McElroy JP, Isobe N, Gourraud PAFD, Cailler GSJ, Matsushita T, Kohriyama T, Miyamoto K, Nakatsuji Y, Miki T, Hauser SL, Oksenberg JR, Kira J:

SNP based analysis of the HLA locus in Japanese multiple sclerosis patients.

Gene Immunity 12: 523-530, 2011

234.Yonekawa T, Matsushita T, Minohara M, Isobe N, Masaki K, Yoshimura S, Nishimura S, Kira J:

T cell reactivities to myelin protein-derived peptides in neuromyelitis optica patients with anti-aquaporin-4 antibody.

Neurology Asia 16: 139-142, 2011

235.Ma L, Ohyagi Y, Nakamura N, Iinuma KM, Miyoshi K, Himeno E, Soejima N, Yanagihara YT, Sakae N, Yamasaki R, Kira J:

Activation of glutathione peroxidase and inhibition of p53-related apoptosis by apomorphine.

J Alzheimer’s Disease 27: 225-237, 2011.

2012

236.Yamasaki T, Goto Y, Ohyagi Y, Monji A, Munetsuna S, Minohara M, Kira J, Kanba S, Tobimatsu S:

Selective impairment of optic flow perception in amnestic mild cognitive impairment: evidence from event-related potentials.

J Alzheimer’s Disease 28: 695-708, 2012

237.Dashjamts T, Yosiura T, Hiwatashi A, Yamashita K, Monji A, Ohyagi Y, Kamano H, Kawashima T, Kira J, Honda H:

Simultaneous actrial spin labeling cerebral blood flow and morphologyical assessments for detection of Alzheimer’s disease.

Acad Radiol 18: 1492-1499, 2011

238.

Shigetou H, Sakata A, Morioka T, Takase K, Hagiwara H, Kamada T, Kanamori Y, Hashiguchi K, Tobimatsu S, Yamashita N, Kira J:

Peri-orbital electrodes as a supplemental recording for detection of ictal discharges in medial temporal loｆbe epilepsy.

Neurology Asia (in press).

239.Riwanti Estiasari, Matsushita T, Masaki K, Akiyama T, Yonekawa T, Isobe N, Kira J;

Comparison of clinical, immunological and neuroimaging features between anti-aquaporin-4 ant body-positive and –negative Sjögren’s syndrome patients with central　nervous system manifestations.

Multiple Sclerosis (in press).

240.Fukunaga Kawamura M, Yamasaki R, Kawamura N, Tateishi T, Nagara Y, Matsushita T,

Ohyagi Y, Kira J:

Impaired recruitment of neuroprotective microglia and T cells during acute neuronal injury coincides with increased neuronal vulnerability in an amyotrophic lateral sclerosis model.

Exp Neurol 234: 437-445, 2012.

241.Isobe N, Kanamori Y, Yonekawa T, Matsushita T, Shigetou H, Kawamura N, Kira J:

First diagnostic criteria for atopic myelitis with special reference to discrimination from myelitis-onset multiple sclerosis.

J Neurol Sci 316: 30-35, 2012.

242.Kakumoto K, Matsumoto S, Nakahara I, Watanabe Y, Fukushima Y, Urabe Y, Ishibashi R,

Gomi M, Tsuji K, Sanbongi Y, Hashimoto T, Tanaka Y, Yamada T, Kira J:

Rapid formation of cerebral microbleeds after carotid artery stenting.

Cerebrovascular Diseases EXTRA 2:9-16, 2012.

243.Isobe N, Yonekawa T, Matsushita T, Kawano Y, Masaki K, Yoshimura S, Fichna J, Chen S, Furmaniak J, Smith BR, Kira J:

Quantitative assays for anti-aquaporin-4 antibody with subclass analysis in neuromyelitis

optica.

Multiple Sclerosis 18: 1541-1551, 2012.

244.Saida T, Itoyama Y, Tashiro K, Kira J, Hao Q, the Interferon Beta-1a Multiple Sclerosis Study Group of Japan:

Intramuscular interferon bata-la is effective in Japanese patients with relapsiny-remitting multiple sclerosis: a pre-treatment versus treatment comparison study of gadolinium-enhanced MRI brain lesions.


245.Saida T, Kikuchi S, Itoyama Y, Hao Q, Kurosawa T, Nagao K, Tang D, Zhang-Auberson L, Kira J:

A randomized, controlled trial of fingolimod (FTY 720) in Japanese patients with multiple sclerosis.


246.Masaki K, Suzuki SO, Matsushita T, Yonekawa T, Matsuoka T, Isobe N, Motomura K, Wu XM, Tabira T, Iwaki T, Kira J:

Extensive loss of connexins in Baló’s disease: evidence for an auto- antibody- independent astrocytopathy via impaired astrocyte-oligodendrocyte/myelin interaction.

Acta Neuropathol 123: 887-900, 2012.

247. Gulibahaer A, Yamashita K, Torii T, Furuta K, Isobe N, Matsushita T, Masaki K, Matsumoto S, Kira J:

Clinical disability progression and platelet GP Ⅱb/Ⅲa values in patients with atopic myelitis.

J Neuroimmunol 246: 108-112, 2012.

248. Sato S, Isobe N, Yoshimura S, Kanamori Y, Masaki K, Matsushita T, Kira J:

HLA-DPB1* 0201 is associated with susceptibility to atopic myelitis in Japanese.

J Neuroimmunol 251: 110-113, 2012.

249. Soejima N, Ohyagi Y, Nakamura N, Himeno E, Iinuma KM, Sakae N, Yamasaki R, Tabira T, Murakami K, Irie K, Kinoshita N, LaFerla FM, Kiyohara Y, Iwaki T, Kira J:

Intracellular accumulation of toxic turn amyloid-β is associated with endoplasmic reticulum stress in Alzheimer’s disease.

Current Alzheimer Research (in press).

250.Yoshimura S*, Isobe N*, Matsushita T, Yonekawa T, Masaki K, Sato S, Kawano Y, Kira J:

Distinct genetic and infectious profiles in Japanese neuromyelitis optica patients according to anti-aquaporin-4 antibody status.

J Neurol Neurosurg Psychiatry 84: 29-34, 2013.

251.Yoshimura S, Isobe N, Yonekawa T, Matsushita T, Masaki K, Sato S, Kawano Y, Yamamoto K, Kira J:

Genetic and infectious profiles of Japanese multiple sclerosis patients.

PLoS ONE (in press).

252. Nakamichi K, Kishida S, Tanaka K, Suganuma A, Sano Y, Sano H, Kanda T, Maeda N, Kira J, Itoh A, Kato N, Tomimoto H, Kurane I, Lim CK, Mizusawa H, Saijo M:

Sequential changes in the non-coding control region sequences of JC polyomaviruses from the cerebrospinal fluid of patients with progressive multifocal leukoencephalopathy.

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Arch Virol (in press).

253. Uehahara T, Yamasaki T, Okamoto T, Koike T, Kan S, Miyauchi S, Kira J, Tobimatsu S:

Efficiency of a “small-world” brain network depends on consciousness level: a resting-state fMRI study.

Cerebral Cortex (in press).

254. Nagara Y, Tateishi T, Yamasaki R, Hayashi S, Kawamura M, Kikuchi H, Motomura Iinuma K, Tanaka M, Iwaki T, Matsushita T, Ohyagi Y, Kira J:

Impaired cytoplastic-nuclear transport of hypoxia-inducible factor-1αin amgotrophic lateral sclerosis.

Brain Pathol (in press).

255. Kikuchi H, Mifune N, Niino M, Kira J, Kohriyama T, Ota K, Tanaka M, Ochi H, Nakane S, Kikuchi S:

Structural equation modeling of factors contributing to quality of life in Japanese patients with multipe sclerosis.

BMC Neurology (in press).

256. Carroll W, Saida T, Kim H, Kira J, Kermode A, Tsai C, Fujihara K, Kusunoki S, Tanaka M, Kim K, Bates D:

A guide to facilitate the early treatment of patients with idiopathic demyelinating disease (multiple sclerosis and neuromyelitis optica).


257. Huang J, Yoshimura S, Isobe N, Matsushita T, Yonekawa T, Sato S, Yamasaki R, Kira J:

A NOTCH4 missense mutation confers resistance to multiple sclerosis in Japanese.

1



258. Isobe N, Yonekawa T, Matsushita T, Masaki K, Yoshimura S, Fichna J, Chen S, Furmania K, Smith BR, Kira J:

Clinical relevance of serum aquaporin-4 levels in neuromyelitis optica.

1


Neurochem Res (in press).

259. Matsushita T, Tateishi T, Isobe N, Yonekawa T, Yamasaki R, Murai H, Kira J:

Chharacteristic cerebrospinal fluid cytokine/chemokine profiles in neuromyelitis optica,

relapsing remitting or primary progressive multiple sclerosis.

1


PLoS ONE (in press).

260. Huang J, Isobe N, Matsushita T, Yoshimura S, Sato S, Yonekawa T, Yamasaki R, Kira J:

Distinct genetic profiles between Japanese multiple sclerosis patients with and without Barkhof brain lesions.

Clin Exp Neuroimmunol (in press).

261. Kanamori Y, Isobe N, Yonekawa T, Matsushita T, Shigeto H, Kawamura N, Yamasaki R, Murai H, Tobimatsu S, Kira J:

Multimodality evoked potentials for discrimination of atopic myelitis and multiple sclerosis.


262. Kamada T, Sun W, Takase K, Shigeto H, Suzuki SO, Ohyagi Y, Kira J:

Spontaneous Seizures in a Rat Model of Multiple Prenatal Freeze Lesioning.

Epilepsy Res (in press).

263. Kanamori Y, Hironaga N, Hagiwara K, Uehara T, Chatani H, Sakata A, Hashiguchi K, Morioka T, Tobimatsu S, Kira J:

Minimum norm estimates analysis in MEG can delineate the onset of interictal epileptic discharges: a comparison with ECoG findings.

Neuro Image: Clinical

1


(in press).

II. Case Report (26 papers)

1989

1. Tanaka K, Yoshimura T, Muratani H, Kira J, Itoyama Y, Goto I:

Familial myopathy with scapuloperoneal distribution, rigid spine, cardiopathy and mitochondrial abnormality.

J Neurol 236: 52-54, 1989

1992

2. Murai H, Kira J, Kobayashi T, Goto I, Inoue H, Hasuo K:

Hypertrophic cranial pachymeningitis due to Aspergillus flavus.

Clin Neurol Neurosurg 94: 247-250, 1992

1993

3. Fujimoto M, Kira J, Murai H, Yoshimura T, Takizawa K, Goto I:

Hypertrophic cranial pachymeningitis associated with mixed connective tissue disease: comparison with idiopathic and infectious pachymeningitis.

Intern Med 32: 510-512, 1993

1994

4. Satake M, Kira J, Yamada T, Kobayashi T:

Raymond syndrome (alternating abducent hemiplegia) caused by a small hematoma at the medial ponto-medullary junction.

J Neurol Neurosurg Psychiatry 58: 261, 1994

1996

5. Arakawa K, Kira J, Kobayashi T:

Central nervous system involvement in a case of amyloid A type amyloidosis.

J Neurol Sci 142: 157-159, 1996

1997

6. Arakawa K, Tobimatsu S, Kira J, Kuwahara Y, Kobayashi T:

Bilateral striate cortex contusion presenting with cerebral asthenopsia rather than cortical blindness.


1998

7. Satake M, Yoshimura T, Yamada T, Kira J:

Subacute multifocal painful neuropathy with spontaneous remission.


2000

8. Taniwaki Y, Hara H, Doh-ura K, Murakami I, Tashiro H, Yamasaki T, Shigeto H, Arakawa K, Araki E, Yamada T, Iwaki T, Kira J:

Familial Creutzfeldt-Jakob disease with D178N-129M mutation of PRNP presenting as cerebellar ataxia without insomnia.

J Neurol Neurosurg Psychiatry 68: 388, 2000

9. Taniwaki T, Minohara M, Hara H, Ohyagi Y, Yamada T, Kira J:

The striatonigral degeneration with motor neuron disease.

J Neurol 247: 395-396, 2000

10. Kikuchi H, Yamada T, Okayama A, Hara H, Taniwaki T, Shigeto H, Sasaki M, Iwaki T, Kira J:

Anti-Ri-associated paraneoplastic cerebellar degeneration without opsoclonus in a patient with a neuroendocrine carcinoma of the stomach.


2002

11. Miura S, Ohyagi Y, Ohno M, Inoue I, Ochi H, Murai H, Furuya H, Yamada T, Kira J:

A patient with delayed posthypoxic demyelination: a case report of hyperbaric oxygen treatment.


2004

12. Tsuruta Y, Ikezoe K, Nakagaki H, Shigeto H, Kawajiri M, Ohyagi Y, Kira J:

A case of dermato-fascitis: amyopathic dermatomyositis associated with fascitis.

Clin Rheumatol 23: 160-162, 2004

13. Watanabe A, Kawajiri M, Ikezoe K, Osoegawa M, Murai H, Ochi H, Taniwaki T, Kira J:

HTLV-1-associated myelopathy/tropical spastic paraparesis accompanied with psoriasis.

J Neurol Sci 221: 95-97, 2004

14. Kawamura N, Ohyagi Y, Kawajiri M, Yoshiura T, Mihara F, Furuya H, Kira J:

Serial diffusion-weighted MRI in a case of Wilson’s disease with acute onset hemichorea.

J Neurol 251: 1413-1414, 2004

2005

15. Matsuse D, Ochi H, Tashiro K, Nomura T, Murai H, Taniwaki T, Kira J:

Exacerbation of chronic inflammatory demyelinating polyradiculoneuropathy during interferon(-1b therapy in a patient with childhood-onset multiple sclerosis.

Intern Med 44: 68-72, 2005

2006

16. Furuya H, Murai H, Takasugi K, Ohyagi Y, Urano F, Kishi T, Ichinose H, Kira J：

A case of late-onset Segawa syndrome (autosomal dominant dopa-responsive dystonia) with a novel mutation of the GTP-cyclohydrase I (GCH1) gene.


17. Matsushita T, Murai H, Kawajiri M, Muratani H, Iwaki T, Taniwaki T, Kira J:

Character changes from idiopathic cranial pachymeninyoencephalitis.

J Neurol Sci 244: 163-166, 2006

18. Murai H, Noda T, Himeno E, Kawano Y, Ohyagi Y, Shiraishi H, Motomura M, Kira J:

Infantile onset myasthenia gravis with Anti-MuSK antibodies.

Neurology 67: 174, 2006

19. Murai H, Tokunaga H, Kubo I, Kawajiri M, Iwaki T, Taniwaki T, Kira J:

Myeloradiculitis caused by Cryptococcus neoformans　infection in a patient with ulcerative colitis: a neuropathological study.

J Neurol Sci 247: 236-238, 2006

20. Doi H, Kikuchi H, Murai H, Kawano Y, Shigeto H, Ohyagi Y, Kira J:

Motor neuron disease associated with chronic pyrethroids intoxication.

Neurology 67: 1894-1895, 2006

21. Kawano Y, Nagara Y, Murai H, Kikuchi H, Ohyagi Y, Kira J:

A case of slowly progressive distal muscular atrophy of the bilateral upper limbs (O'Sullivan-McLeod syndrome) partially alleviated by intravenous immunoglobulin therapy.

Intern Med 46: 515-518, 2006

2008

22. Hagiwara K, Murai H, Ochi H, Osoegawa M, Shigeto H, Ohyagi Y, Kira J:

Upper motor neuron syndrome associated with subclinical Sjögren syndrome.

Inter Med 47: 1047-1051,2008

23. Kuroki N, Ohyagi Y, Kawano Y, Yoshiura T, Taniwaki T, Kira J: Acute onset idiopathic trigeminal sensory neuropathy (Images in Neuroscience).

J Clin Neurosci 15: 1049, 2008

2009

24. Hokonohara T, Shigetou H, Kawano Y, Uehara M, Ohyagi Y, Kira J:Facial onset sensory and motor neuronopatly (FOSMN) syndrome responding to immunotherapies.

J Neurol Sci 275: 157-158, 2009.

25. Hagiwara K, Ochi H, Suzuki S, Shimizu Y, Tokuda T, Murai H, Shigeto H, Ohyagi Y, Iwata M, Iwaki T, Kira J:Highly selevtive leptomeningeal amyloidosis with transthyretin variant Ala25ThrNeurology 72: 1358-1360, 2009.

26. Doi H, Hashimoto S, Kira J:Transient burning pain in the ipsilateral orbit as an initial mamifection of dorsal portine hemorrhage.Neueologia Medico-chirurgica 49: 206-208, 2009

2010

27. Dashjamts T, Yoshiura T, Hiwatashi A, Yamashita K, Abe K, Ohyagi Y, Kira J, Honda H:

Asymmetrical cerebral perfusion demonstrated by noninvasive arterial spin-labelling perfusion imaging in a patient with corticobasal degeneration.

Jpn J Radiol 28: 75-78, 2010

2011

28. Shinoda K, Matsushita T, Furuta K, Isobe N, Yonekawa T, Ohyagi Y, Kira J:Wall-eyed bilateral internuclear ophthalmoplegia (WEBINO) syndrome in a patient with Neuromyelitis optica spectrum disorder and anti-aquaporin-4 antibody.Mult Scler 17: 884-886, 2011

29. Doi H, Arimura K, Ohyagi Y, Kira J:Frostbite-like skin lesion as an autonomic symptom in Isaacs' syndrome.Intern Med 50: 1113-1115, 2011

30. Iwata T*, Shigeto H*, Ogata K, Hagiwara K, Kanamori Y, Uehara T, Ohyagi Y, Tobimatsu S, Kira J:Hyperexcitability restricted to the lower limb motor system in a patient with stiff-leg syndrome.J Clin Neurosci 18: 1720-1722, 2011 *Equal contribution.

31. Uehara T, Murai H, Yamasaki R, Kikuchi H, Shigeto H, Ohyagi Y, Kira J:Thymoma-associated progressive encephalomyelitis with rigidity and myoclonus successfully treated with thymectomy and intravenous immunoglobulin.Eur Neurol 66: 328-330, 2011

32. Takase K *, Shigeto H, Furuta K, Sakae N, Ohyagi Y, Kira J:

Transient Vocal Cord Palsy Caused by Hypoperfusion of Unilateral Hemisphere.

Fukuoka Acta Med 102: 273-276, 2011.

2012

33. Watanabe M, Ochi H, Arahata H, Matsuo T, Nagafuchi S, Ohyagi Y, Kira J:

Myopathy in a sutoimmune polyendocrinopathy-candiliasis-ecotodermal dystrophy.

Muscle Nerve (in press).

34. Saiga T, Tateishi T, Torii T, Kawamura N, Nagara Y, Shigeto H, Hashiguchi A, Takashima H, Honda H, Ohyagi Y, Kira J:

Inflammatory radiculoneuropathy in an ALS4 patient with a novvel SETX mutation.

J Neurol Neurosurg Psychiatry (in press).

35. Sonoda T, Yamasaki R, Matsushita T, Yoshimura T, Murai H, Kira J:

A case of CLIPPERS showing features common to multiple sclerosis.


36. Saitoh B, Yamasaki R, Hayashi S, Yoshimura S, Tateishi T, Ohyagi Y, Murai H, Iwaki T, Yoshida K, Kira J:

A case of hereditary diffuse leukoencephalopathy with axonal spheroids caused by a de novo mutation in CSF1R masquerading as primary progressive multiple sclerosis A case of CLIPPERS showing features common to multiple sclerosis.

Mult Scler (in press).

Review

1998

1. Nishimura Y, Oiso M, Fujisao S, Kanai T, Kira J, Chen YZ, Matsushita S:

Peptide-based molecular analysis of HLA class II-associated susceptibility to autoimmune diseases.

International Reviews of Immunology 17: 229-262, 1998

2. Nishimura Y, Kanai T, Oiso M, Tabata H, Ito H, Kira J, Chen YZ, Matsushita S:

Molecular analysis of HLA class II-associated susceptibility to subtypes of autoimmune diseases unique to Asians.

Internatinal Journal of Cardiology 66 (Suppl 1): S93-S105, 1998

1999

3. Kira J:

Focal brain lesions in acquired immunodeficiency syndrome: DNA diagnosis and further monitoring.

Intern Med 38: 521, 1999

2000

4. Kira J :

A novel feature disclosed in opticospinal multiple sclerosis in Asians.

Intern Med 39: 272, 2000

2002

5. Kira J：

Atopy and neural damage.

Intern Med 41: 169-174, 2002

2003

6. Kira J:

Multiple sclerosis in the Japanese population.

Lancet Neurology 2: 117-127, 2003

2005

7. Kira J:

Girdle sensation masquerading splanchnopathy in neurosarcoidosis.

Intern Med 44: 531-532, 2005

2006

8. Kira J:

Geographical influence: MS Genetics in Japan.

MS IN FOCUS Issue 8: 19, 2006

9. Kira J:

Vogt-Koyanagi-Harada disease and polymorphonuclear leuokocytic pleocytosis in cerebrospinal fluid.

Intern Med 45: 839-840, 2006

2008

10. Kira J:

MS: prevention of neural damage by early intervention.

Lancet Neurology 7: 3-5, 2008

11. Kira J:

　　　Neuromyelitis optica and Asian phenotype of multiple sclerosis.

Annals of the New York Academy of Sciences 1142: 58-71, 2008

12. Kira J, Ishizu T, Osoegawa M:

Multiple sclerosis in Japan: nationwide surveys over 30 years.

Neurology Asia 13: 131-143, 2008.

2009

13. Polman C, Miller D, Weinshenker B, Filippi M, Banwell B, Cohen J, Freedman M, Galetta S, Hutchinson M, Johnson R, Kappos L, Kira J, Lublin F, McFarland H, Montalban X, Panitch H, Richert J, Reingold S:

Differential Diagnosis of Suspected Multiple Sclerosis: A Consensus Approach

Multiple Sclerosis 14: 1157-1174, 2009

2010

14. Kira J, Matsushita T, Isobe N, Ishizu T:

Opticospinal multiple sclerosis in Japanese.

Neurology Asia 13: 167-173, 2010.

15. Kira J, Ishizu T, Osoegawa M:

Multiple sclerosis in Japan: nationwide surveys over 30 years.Neurology Asia 13: 131-143, 2008

2009

16. Kira J: Neuromyelitis optica and opticospinal multiple sclerosis:mechanisms and pathogenesis.Pathophysiology 18: 69-79, 2011

2010

17. Kira J:Astrocytopathy in Baló’s disease.Mult Scler 17:771-779, 2011.

2011

18. Kira J:

Autoimmunity in neuromyelitis optica and opticospinal multiple sclerosis: astrocytopathy as a common denominator in demyelinating disorders.

J Neurol Sci 311: 69-77, 2010.

19.Kira J:

The Expanding phenotype of CLIPPERS: is it a disease or a syndrome?

J Neurol Neurosurg Psychiatry 83: 2-3, 2012.

2012

20. Kira J:Genetic and environmental backgrounds responsible for the change in the phenotype ofMS in Japanese subjects.

Multiple Sclerosis and Related Disorders 1: 188-195, 2012.

Books

1988


Surface marker expression and encephalitogenic potency of BP-cultured spleen cells.

Neuroimmunological Disease (edited by Igata A.), Univ Tokyo Press, pp. 151-157, 1988


Altered peripheral blood lymphocytes in HTLV-I-associated myelopathy (HAM).

Neuroimmunological Disease (edited by Igata A), Univ Tokyo Press, pp. 23-26, 1988

1989

3. Itoyama Y, Minato S, Kira J, Goto I, Okochi K, Yamamoto N:

Immunological aspects of HTLV-I-associated myelopathy (HAM).

HTLV-I and The Nervous System (edited by Roman GC, Vernant J-C and Osame M), Alan R Liss Inc, pp. 287-295, 1989

1992

4. Tabira T, Kira J:

Strain and species differences of encephalitogenic determinants of myelin basic protein and proteolipid apoprotein.

Myelin (edited by Martenson RE), CRC Press, pp. 783-798, 1992

1998

5. Arakawa K, Tobimatsu S, Kira J, Kato M:

Parvocellular and magnocellular visual deficits in neurological diseases: an ERP study.

Recent Advances in Human Neurophysiology (I. Hashimoto and R. Kakigi, eds), pp. 489-495, 1998

2001

6. Kikuchi H, Yamada T, Iwaki T, Kira J：

Expression of cathepsins in the motor neurons of amyotrophic lateral sclerosis.

Molecular mechanism and therapeutics of amyotrophic lateral sclerosis.

Ed by K. Abe

Elsevier Science BV pp. 27-33, 2001

2002

7. Kira J:

Two distinct form of multiple sclerosis in Asians: opticospinal form and conventional form.

Advances in Clinical Neurosciences 12

Ed by Sinha K K, Chandra P.

Catholic Press, Jharkhand. pp. 101-116, 2002

2005

8. Shigeto H, Uehara T, Uchida K, Nomura T, Taniwaki T, Kira J:

Thalamic involvement of status epilepticus: diffusion-weighted image of MRI in two cases of status epilepticus.

Unveiling the mystery of the brain: Neurophysiological investigation of the brain function.

International Congress Series 1278, Neurology.

Edited by Tsuji S, Tobimatsu S, Kakigi R, Uozumi T, Akamatsu N.

Elsevier (Amsterdam) pp. 193-196, 2005

2006

9. Kira J：

Etiology of multiple sclerosis.

WFN Seminars in Clinical Neurology.

Edited by Oger J, Al-Aragi A.

Demos Medical Pub. Inc. (New York) pp. 1-6, 2006

10. Kira J, Matsushita T, Matsuoka T:

Aquaporin 4 autoimmunity in multiple sclerosis in Japanese.

Ed. by Tabira T, Yamamura T, Kira J.

Current Topics in Neuroimmunology

Medimond pp. 33-39, 2006

2008

11. Lisak R, Kira J:Multiple sclerosis.International Neurology. A Clinical Approach.Ed. by Lisak R, Truong D, Carrol W, Bhidayasiri R.Blackwell pp. 366-374, 2009

2009

12. Ohyagi Y, Miyoshi K, Ma L, Motomura K, Kira J:Mechanisms of neurodegeneration and therapeutic strategies for neuroprotection in Alzheimer's disease.Recent Advances in Neurogenesis, Neuroregeneration and NeuroprotectionEd. By Suzuki SO, Yonemitsu YResearch Signpost pp. 19-46, 2009

2010

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Documents

吉良潤一 業績目録 - 九州大学（KYUSHU UNIVERSITY） · Web viewJun-ichi Kira, Kyushu Univeristy List of Publication in English Original Article 2 63 (1’ Author 35) Case

吉良潤一業績目録 - 九州大学（KYUSHU UNIVERSITY） · Web viewJun-ichi Kira, Kyushu Univeristy List of Publication in English Original Article 2 63 (1’ Author 35) Case