【黃志揚博士簡介】cmucms.cmu.edu.tw/huang1020521.pdf · 第27屆(2012年)生醫聯合學術年會壁報論文競賽生化分生組獲得優勝(賴益平) 第28屆(2013年)生醫聯合學術年會看板論文競賽生理組榮獲第三名(林依霖);

【黃志揚博士簡介】

黃志揚博士於 1987 畢業於輔仁大學食營系完成學士學位同年考上五間大學研究所並以榜首

考入陽明大學生理所攻讀心臟學內分泌碩士學位1989 年獲陽明大學碩士畢業生最高榮譽伊旬諾論

文獎並於 1989 年任職 39 期預官訓實習連長後轉任國軍 333 師營站主任於 1991 年完成義務

役少尉軍階義務1992年申請獲五所美國大學博士班研究獎學金選擇美國伊利諾大學香檳城分子

生理所提供之全額獎助學金加入當時任美國癌症協會副主席（現任美國內分泌主席）Benita S

Katazenbogen 教授實驗室完成乳癌分子生物學碩士學位1995年至 Dennis E Buetow 教授實驗室

轉攻心臟分子訊息生物學於 1998 年獲得伊利諾大學博士學位並於原實驗室繼續擔任博士後研

究員一年於 1999 年八月回台首任職於台中中山醫學大學擔任助理教授一職於 2002年 8月升

任部定副教授並於 2004年 8 月兼任創新育成中心主任2005年 10月正式榮升部定教授一職並

於 2000-2005間同時擔任國立中正大學分生所兼任教授2006年 8月獲中國醫藥大學聘任教授兼任

基礎醫學研究所所長另於 2009 年 8 月同時兼任副研發長一職2005 年迄今同時擔任亞洲大學暨

宏光科大兼任教授2013年迄借調亞洲大學生科系特聘教授兼研發處研發長目前研究主題包含探

討類胰島素生長因子接受體（IGF-IR）調控心肌細胞存活及 IGF-IIR 誘發心肌細胞凋亡機轉探討

並研究女性雌激素及其受體之心肌保護機轉同時進行多種癌症抑制神經再生及中醫藥之研究

目前主持（含共同）9 件國科會計畫5 件校內10 件校外合作計劃同時擔任國科會計畫初審及

覆審委員考選部高考出題及審題委員中醫大亞洲醫學雜誌及 BioMedicine 副主編中國生理學

雜誌（SCI）副主編調適醫學雜誌World Journal of Oncology World Journal of Moleucular Biology

等編輯委員至 2013年共發表 SCI ndashpapers (gt200 篇)

姓名黃志揚教授 Chih-Yang Huang

研究方向心臟分子生化及癌症分子醫學

研究室分子醫學研究室

學校(04-22053366)分機(O)3313 (L)3315 3316

醫院(04-22052121)分機(O)7716 7701 (L)7707

亞洲大學 04-23323456 分機(O)6140

E-mailcyhuangmailcmuedutw or cyhuangasiaedutw

現職 | 學歷 | 經歷 | 專長 | 榮譽 | 研究方向 | 合作實驗室 | 研究室成員 |

| 學術論文及著作 |

【現職】

亞洲大學生科系特聘教授兼研發處研發長

中國醫藥大學暨附設醫院桂冠研究人才計畫主持人

中國附醫醫學研究部 (顧問)

中國醫藥大學醫學院中醫學院共同實驗室負責人

中國醫藥大學基醫所中醫所臨醫所合聘教授

中醫大 BioMedicine 醫學雜誌副總編輯中國生理學雜誌(CJP SCI)及調適醫學雜誌編輯

國科會生物處專題研究計畫初複審委員及考選部高考出題審題委員

弘光科技大學營養醫學研究所兼任教授

【學歷】

國立陽明大學生理所心臟內分泌學碩士(1987-1989)

美國伊利諾大學香檳校區分子生理所乳癌分子醫學碩士(1992-1995)

美國伊利諾大學香檳校區分子生理所心臟分子醫學博士(1995-1998)

美國伊利諾大學香檳校區分子生理所心臟分子醫學博士後研究(1998-1999)

【經歷】

國立陽明大學生理學兼任助教(1987-1989)

中華民國國軍 39 期預官(醫勤官兼 333 師營站主任)(1989-1991)

美國伊利諾大學香檳校區分子生理所助理及助教(1992-1996amp1996-1998)

國立中正大學分子生物研究所兼任教授(2000-2008)

中山醫學大學生化暨生物科技研究所助教授(19998-20027)

中山醫學大學生化暨生物科技研究所副教授(20028-200510)

中山醫學大學生化暨生物科技研究所教授(200510-20067)

中山醫學大學創新育成中心主任(20058-20067)

中國醫藥大學基礎醫學研究所所長(200611-20131)兼副研發長(20098-20131)

中國生理學雜誌(CJP SCI)暨中醫大中台灣醫學雜誌副總編輯(20098-20131)

【榮譽】

中國醫藥大學 2006-2009-2012 傑出教授研究獎

中國醫藥大學醫學院 96-101 學年度(RPICJA 及論文篇數)研究績優獎

輔仁大學營養科學系傑出系友獎 (2008 第三屆 Outstanding Alumni Award of Nutritional Science

Department Fu-Jen University Taiwan)

台中市建功國小立人中學傑出校友獎(2009)

國立陽明大學尹旬諾論文獎(第三屆)

台灣調適醫學會理事(2007-2013)

Adaptive Medicine 特約作者(2006-2009) 編輯委員(2009-2013)

工研院生醫所無給職顧問(2009 迄)

台中市莉程生物科技公司顧問(2006-2008)

台中縣一品堂中醫體系科技顧問(2008 迄今)

2009 生醫年會 March 21-22 24 th生理學 Cardiovascular Biology Section Program Organizer and invited

speaker

2009 International Conference of Adaptive Medicine Society Aug 2-5 Taipei Organizing board member

and invited speaker

中國西安交通大學暨附屬醫院參訪學者20090704 至 20090712

BITs 1st Annual International Congress of Cardiology-2009 Shanghai China Dec 5-7

Co-Chair and invited speaker

受邀擔任第七屆亞太生理學聯盟學術大會中醫藥替代醫學 Satellite Symposium 籌備主席

2012 年 1 月 8-15 日受邀埃及擔任國際博士生 Ehab Abdelfadil 口試委員

擔任最新腧穴圖鑑學術刊物編審委員

【指導研究生論文獲獎】

19th (劉忠榮)amp 21 th (朱俊憲)生醫年會生化分生優秀壁報獎

23 th (郭昱均)生醫年會生理學優秀壁報獎

3rd中正大學分生所論文獎 1st 名(王惠勵)

1rd中山醫學大學生化所論文獎 1st 名(顏均宇)

1rd中國醫藥大學國際生醫研討暨研究生發表會壁報獎 1st 名(顏均宇)

1rd中國醫藥大學生科所研究生發表會壁報獎 1st 名(李振宇)

2009 International Conference of Adaptive Medicine Society 發表會壁報獎1st名(陳德勇越南籍生)

第27屆(2012年)生醫聯合學術年會壁報論文競賽生化分生組獲得優勝(賴益平)

第28屆(2013年)生醫聯合學術年會看板論文競賽生理組榮獲第三名(林依霖)

生化分生組優秀壁報獎(陳佳華劉俊宏)

【研究室成員】gt40 位

黃志揚教授郭薇雯教授

博士後研究陳冬生博士 VELMURUGAN BHARATH KUMAR 博士 MARTHANDAM ASOKAN

SHIBU 博士

外籍生Dr Ehab Abd Assistant Professor Faculty of Dentistry Mansoura University Egypt

研究助理賴明秀李念鴻劉憶帆江艾芝張欣農葉慈馨林文政林展鈺吳恩婷

陳政傑李信億劉靜璇蔡湘儀陳怡均洪孟愉徐娟珍

CATHERINE REENA PAUL

基礎研究生賴美智(博六共)翁悅珊(博五)林町餘(博四)丁韋仁(博三)楊承訓(博三)

吳嘉平(博三)廖柏翔(博二)曾千育(博一)洪翠舷(博一)劉俊宏(研二)

周彥宏(研二)陳佳華(研二)劉珮潔(研二共)林依霖(研二共)陳韻安(研

二)林怡君(研一)蔡佾倢(研一)陳劭瑀(研一)魏妤珉(研一)莊授瑛(研一)

臨床研究生張勝皇(博七)陳維恭(博七)賴昭宏(博三)林殿璜(博三共)林志學(博三)

胡幃勛(博二)蔡承諺(博二)陳明正(博二)林冠合(博二)陳裕鋒(博二)

陳業鵬(博二)馮志中(博一)張瑞麟(博一)賴金湖(博一)

大學部專題生孫麗棻葉玟瑄郭品岑林宭卉張雯喻林鳳儒林進輝汪正怡謝佩渝

簡上鈞

【擔任 reviewer】

Journal reviewer International J of Cardiology Chinese J of Physiol Molecular Cellular

Biochemistry Journal of molecular and cellular cardiology Clinica Chima Acta Pharmacology research

Journal of Cardiovascular Pharmacology Clinical Biochemistry Apoptosis Acta Pharmacologica Sinica

eCAM J of Endocrinology J of Molecular Medicine Endocrinology

Project reviewer Philip Morris external Research Program Tzu Chi human clinical trail project

Taichung Veterans General Hospital project NSC group projects

【研究方向】

1 雌性素(Estrogen)及其受體基因轉殖在心血管疾病阻斷及肝癌直腸癌口腔癌前列腺癌防治機

轉探討癌症幹細胞移除機制研究

2 心肌細胞中鈣離子調控之激脢去磷酸根脢及細胞激素之角色

3 心肌細胞肥厚及猝死之起始因子(含生長因子發炎等)及臨床診斷指標(Clinicalbiochemical

markers)尋找

4 IGF-I 及 IGF-II 在心肌細胞之交互調控角色探討

5 醣尿病患及動物併發心血管疾病過程中其機轉及臨床診斷指標探討

6 DNA 基因晶片在各種心肌疾病及肝癌直腸癌的應用

7 心肌細胞肥厚過程中Cytochrome-c-oxidase 活性及基因表現的差異

8 針灸的降血壓及抑心肌肥大分子機轉探討

9 強心促肝及神經細胞再生中藥材複方篩選及其單一成分調控之分子迅息探討並分析其與西

藥之混合療效中草藥抗心肌肥厚及心肌凋亡療效評估及機轉探討

10 運動介入對血酯肪所誘導之心肌細胞肥厚拮抗作用及先天基因性肥胖鼠(Zucker)心肌病變分

子迅息機轉研究

11 低氧低壓的心肌傷害及心肌細胞適應之分子機轉及鐵離子之氧化傷害評估

12 臨床心室中隔缺損病患及手術前後心肌組織之基因表現差異及梗塞組織之基因 SNP 掃瞄

13 Translational Study of 負電性低密度脂蛋(L5)-Mediated Diabetic Cardiomyopathy

14 SDF-1CXCR4 調控 MMP29 訊息在血管內皮幹細胞(hUCB34-EPCs)引導中風血管新生過程之機

轉探討

15 Rejuvenating the aging brain by modulating NMDA-glycine receptor activity genetic manipulation

【學術論文及著作】國際 SCI 期刊已接受發表gt200 篇

2008-2013 文章

1 Chien-Chung Lin Tung-Sheng Chen Yueh-Min Lin Yu-Lan Yeh Yi-Hui Li Wei-Wen Kuo Fuu-Jen

Tsai Chang-Hai Tsai Shiow-Kang Yen Chih-Yang Huang The p38 and NFκB signaling protein

activation involved in glycitein protective effects on isoproterenol-treated H9c2 cardiomyoblast cells

J O U R N A L O F F U N C T I O N A L F O O D 2013 5 460-465(Correspondence Author)

2 Tsai KH Lee NH Chen GY Hu WS Tsai CY Chang MH Jong GP Kuo CH Tzang BS Tsai FJ

Tsai CH Chih-Yang HuangDung-shen (Codonopsis pilosula) attenuated the cardiac-impaired

insulin-like growth factor II receptor pathway on myocardial cells FOOD CHEMISTRY 2013

138(2-3)1856-67(Correspondence Author)

3 Kun-Hsi Tsai Hau-Hsueh Hsien Li-Mien ChenWei-Jen TingYuh-ShyongYangChia-Hua Kuo

Chang-Hai Tsai Fuu-Jen Tsai Henry J TsaiChih-Yang Huang Rhubarb inhibits hepatocellular

carcinoma cell metastasis via GSK-3-b activation to enhance protein degradation and attenuate

nuclear translocation of b-catenin Food Chemistry 2013 138 278ndash285 (co-correspondence Author)

4 Hou CW Tsai YS Jean WH Chen CY Ivy JL Chih-Yang Huang Kuo CH Deep Ocean Water

Accelerates Recovery from Physical Fatigue Journal of the International Society of Sports

Nutrition2013 10(1)7 (co-correspondence Author)

5 Hsia TC Tu CY Chen YJ Wei YL Yu MC Hsu SC Tsai SL Chen WS Yeh MH Yen CJ Yu YL

Huang TC Chih-Yang Huang Hung MC Huang WC Lapatinib-mediated COX-2 expression via

EGFRHuR interaction enhances the aggressiveness of triple-negative breast cancer cells

MOLECULAR PHARMACOLOGY 2013 83(4)857-69

6 Chung-Hsiang Liu Yi-Wen Lin Nou-Ying Tang Hsu-Jan Liu Chih-Yang Huang Ching-Liang

Hsieh Effect of Oral Administration of Pheretima Aspergillum (Earthworm) in Rats with Cerebral

Infarction Induced by Middle-Cerebral Artery Occlusion African Journal of Traditional

Complementary and Alternative Medicines2013 10(1)66-82

7 Ehab Abdelfadil Ya-Hsin Cheng Da-Tian BauWei-Jen TingLi-Mien Chen Hsi-Hsien Hsu

Yueh-Min LinRay-Jade ChenFu-Jenn TsaiChang-Hai Tsai Chih-Yang Huang Thymoquinone

induces apoptosis in oral cancer cells through P38β inhibition AMERICAN JOURNAL OF

CHINESE MEDICINE 2013 in press (Correspondence Author)

8 Lu DY Chen JH Tan TW Chih-Yang Huang Yeh WL Hsu HC Resistin protects against

6-hydroxydopamine-induced cell death in dopaminergic-like MES235 cells JOURNAL OF

CELLULAR PHYSIOLOGY2013 228(3)563-71 (Correspondence Author)

9 Wu MH Chen LM Hsu HH Lin JA Lin YM Tsai FJ Tsai CH Chih-Yang Huang Tang CH

Endothelin-1 enhances cell migration through COX-2 up-regulation in human chondrosarcoma

BIOCHIMICA ET BIOPHYSICA ACTA-GENERAL SUBJECTS 2013 1830(6)3355-64

(co-correspondence Author)

10 Cheng YC Chang MH Tsai CC Chen TS Fan CC Lin CC Lai CH Tsai FJ Lin JA Chih-Yang

Huang Garlic oil attenuates the cardiac apoptotosis in hamster-fed with hypercholesterol diet

FOOD CHEMISTRY 2013 136(3-4)1296-302 (Correspondence Author)

11 Weng YS Kuo WW Lin YM Kuo CH Tzang BS Tsai FJ Tsai CH Lin JA Hsieh DJ Chih-Yang

Huang Danshen mediates through estrogen receptors to activate Akt and inhibit apoptosis effect of

Leu27IGF-II-induced IGF-II receptor signaling activation in cardiomyoblasts FOOD AND

CHEMICAL TOXICOLOGY 2013 5628-39 (Correspondence Author)

12 Tsai CC Wu JP Lin YM Yeh YL Ho TJ Kuo CH Tzang BS Tsai FJ Tsai CH Chih-Yang Huang

The effect of Elephantopus scaber L on Liver Regeneration after Partial Hepatectomy

Evidence-based Complementary and Alternative Medicine2013 2013369180 (Correspondence

Author)

13 Liu TC Lin CH Chih-Yang Huang Ivy JL Kuo CH Effect of acute DHEA administration on free

testosterone in middle-aged and young men following high-intensity interval training EUROPEAN

JOURNAL OF APPLIED PHYSIOLOGY2013 (Correspondence Author)

14 Chang YM Tsai CT Wang CC Chen YS Lin YM Kuo CH Tzang BS Chen RJ Tsai FJ

Chih-Yang Huang Alpinate Oxyphyllae Fructus (Alpinia Oxyphylla Miq) Extracts Inhibit

Angiotensin II Induced Cardiac Apoptosis in H9c2 Cardiomyoblast Cells BIOSCIENCE

BIOTECHNOLOGY AND BIOCHEMISTRY2013 77(2)229-34 (Correspondence Author)

15 Chou SH Lin SZ Day CH Kuo WW Shen CY Hsieh DJ Lin JY Tsai FJ Tsai CH Chih-Yang

Huang Mesenchymal Stem Cell Insights Prospects in Hematological Transplantation CELL

TRANSPLANTATION 2013

16 Chia M Liao CA Chih-Yang Hu ng Lee WC Hou CW Yu SH Harris MB Hsu TS Lee SD

Reducing body fat with altitude hypoxia training in swimmers role of blood perfusion to skeletal

muscles CHINESE JOURNAL OF PHYSIOLOGY 2013 56(1)

17 Tran Duc Dunga Yueh-Min Linb Wei-Wen Kuoc Peiying Pai d Li-Chin Chung Sheng-Huang

Changf Hsi-Hsien Hsug Fuu-Jen Tsaia Li-Mien Chenh Chih-Yang Huang Zanthoxylum

avicennae extract suppresses plasminogen activators and MMP-2-9 pathway to inhibit the migration

and invasion effects via phosphatase 2A activation of HA22T human hepatocellular carcinoma cells

in vitro and in vivo BBB 2013 in press (Correspondence Author)

18 Pei-Pei Lin You-Miin Hsieh Wei-Wen Kuo Yueh-Min Lin Yu-Lan Yeh Chien-Chung Lin Fuu-Jen

Tsai Chang-Hai Tsai Cheng-Chih Tsai Chih-Yang Huang Suppression of TLR-4-Related

Inflammatory Pathway and Anti-Fibrosis Effects of Probiotic-Fermented Purple Sweet Potato Yogurt

in Hearts of Spontaneously Hypertensive Rats Chinese Journal of Physiology 201356(3)

(Correspondence Author)

19 Chin-Chuan TsaiJia-Ping WuYueh-Min Lin Yu-Lan Yeh Tsung-Jung Ho Chia-Hua KuoBor-Show

TzangFuu-Jen TsaiChang-Hai Tsai Chih-Yang Huang The Effect of Elephantopus scaber Lon

Liver Regeneration afterPartial Hepatectomy Evidence-Based Complementary and Alternative

Medicine2012 2013369180 (Correspondence Author)

20 Mei-Chih ChenChih-Yang HuangShih-Lan Hsu Eugene Lin Chien-Te KuHo LinChuan-Mu

Chen Retinoic Acid Induces Apoptosis of Prostate Cancer DU145 Cells through Cdk5

Overactivation Evidence-Based Complementary and Alternative Medicine2012 2012580736

21 Yung-Ming Chang Chuan-Te Tsai Chiun-Chuang Roger Wang Yueh-Sheng Chen Yueh-Min Lin

Chia-Hua Kuo Bor-Show TzangRay-Jade Chen Fuu-Jen Tsai Chih-Yang Huang Alpinate

Oxyphyllae Fructus (Alpinia Oxyphylla Miq) Extracts Inhibit Angiotensin II Induced Cardiac

Apoptosis in H9c2 Cardiomyoblast Cells BBB2012 77(2)229-34 (Correspondence Author)

22 Tung-Sheng Chen Mu-Hsin Chang Wei-Wen Kuo Yueh-Min Lin Yu-Lan Yeh Cecilia Hsuan Day

Chien-Chung Lin Fuu-Jen Tsai Chang-Hai Tsai Chih-Yang Huang Maldi-tof mass spectrometry

analysis of small molecular weight compounds (with molecular weight under 10 KDa) as

biomarkers of rat hearts undergoing arecoline challenge Pharmaceutical Biology 2012 Early Online

1ndash4 (Correspondence Author)

23 Chih-Yang HuangChien-Hsun LinTung-Tso Ho Hui-Chen Chen Mei-Yun Chu Wei-Shen

SunWei-Chien KaoShan-hui HsuHuey-Shan Hung Enhanced migration of Whartonrsquos jelly

mesenchymal stem cells grown on polyurethane nanocompositesJournal of Medical and Biological

Engineering2012 (First Author)

24 Shin-Da LeeWoei-Cherng Shyu I-Shiung Cheng Chia-Hua Kuo Yi-Sheng Chan Yueh-Min Lin

Ching-Yi Tasi Chang-Hai Tsai Tsung-Jung Ho Chih-Yang Huang Effects of exercise training on

cardiac apoptosis in obese rats NUTRITION METABOLISM AND CARDIOVASCULAR

DISEASES2012 1-9 (co-correspondence Author)

25 Tung-Yuan Lai Yi-Jiun Weng Wei-Kung Chen Yueh-Min Lin Fuu-Jen Tsai Yi-Chang Cheng

Li-Mien Chen Eric YC Lai Chih-Yang Huang Jin-Ming Hwang The Anti-Hepatitis Effect by

Tao-He-Cheng-Qi-Tang on Acetaminophen (APAP) Induced Rats Adaptive Medicine2012 3(1)


26 Li PC Chiu YW Lin YM Day CH Hwang GY Pai P Tsai FJ Tsai CH Kuo YC Chang HC Liu JY

Chih-Yang Huang Herbal Supplement Ameliorates Cardiac Hypertrophy in Rats with CCl 4

-Induced Liver Cirrhosis Evid Based Complement Alternat Med

20122012139045(co-correspondence Author)

27 Hwang JM Ting WJ Wu HC Chen YJ Tsai FJ Chen PY Liu CY Chou LC Kuo SC Chih-Yang

Huang KHC-4 Anti-Cancer Effects on Human PC3 Prostate Cancer Cell Line Am J Chin Med

201240(5)1063-71 (co-correspondence Author)

28 Hwang JM Wu CH Kuo WW Jong GP Lai CH Tsai CH Tsai FJ Chang MH Wu JP Chih-Yang

Huang Pro-inflammation and pro-fibrosis factors were highly induction in heart tissues of carotid

arteries balloon-injured animal model Cell Biochem Funct 2012 Jul30(5)390-4


29 Wei-Syun Hu Jin-Ming Hwang Ying-Lan Tsai Chia-Hua Kuo Gwo-Ping Jong Wu-Hsien Kuo

Fuu-Jen Tsai Chang-Hai Tsai Li-Chin Chung Chih-Yang Huang Association of Serum Cytokines

Human Growth Hormone Insulin-Like Growth Factor (IGF)-I IGF-II and IGF-Binding Protein

(IGFBP)-3 with Coronary Artery Disease CHINESE JOURNAL OF PHYSIOLOGY 2012 55(4)


30 Wang HF Tseng CY Chang MH Lin JA Tsai FJ Tsai CH Lu YC Lai CH Chih-Yang Huang Tsai

CC Anti-Inflammatory Effects of Probiotic Lactobacillus paracasi on Ventricles of BALBC Mice

Treated with Ovalbumin Chin J Physiol 2012 Feb 2955(1)37-46

31 Cooper EL Balamurugan M Chih-Yang Huang Tsao CR Heredia J Tommaseo-Ponzetta M

Paoletti MG Earthworms Dilong Ancient Inexpensive Noncontroversial ModelsMay Help Clarify

Approaches to IntegratedMedicine Emphasizing Neuroimmune Systems Evid Based Complement

Alternat Med 20122012164152

32 Chiu CC Chih-Yang Huang Chen TY Kao SH Liu JY Wang YW Tzang BS Hsu TC Beneficial

Effects of Ocimum gratissimum Aqueous Extract on Rats with CCl4-Induced Acute Liver Injury

Alternat Med 2012 2012736752

33 Dung TD Day CH Binh TV Lin CH Hsu HH Su CC Lin YM Tsai FJ Kuo WW Chen LM

Chih-Yang Huang PP2A mediates diosmin p53 activation to block HA22T cell proliferation and

tumor growth in xenografted nude mice through PI3KndashAktndashMDM2 signaling suppression Food

Chem Toxicol 2012 May50(5)1802-10 (Correspondence Author)

34 Tung-Sheng Chen Show-Yih Liou Hsi-Chin Wu Fuu-Jen Tsai Chang-Hai Tsai Chih-Yang Huang

Yen-Lin Chang Amino acids with basic amino side chain accelerate the pro-oxidant ability of

polyphenolic compounds FOOD CHEMISTRY 2012 (co-correspondence Author)

35 Tung-Sheng Chen Show-Yih Liou Hsi-Chin Wu Miao-Lin Wu Fuu-Jen Tsai Chang-Hai

TsaiChih-Yang Huang Yen-Lin Chang The application of ( )-epigallocatechin gallate in

preparation of an antioxidant dialysate FOOD CHEMISTRY 2012 in press (co-correspondence

Author)

36 Cheng SM Ho TJ Yang AL Chen IJ Kao CL Wu FN Lin JA Kuo CH Ou HC Chih-Yang

Huang Lee SD Exercise training enhances cardiac IGFI-RPI3KAkt and Bcl-2 family associated

pro-survival pathways in streptozotocin-induced diabetic rats Int J Cardiol 2012 Feb 16 [Epub

ahead of print] (co-correspondence Author)

37 Dung TD Chang HC Binh TV Lee MR Tsai CH Tsai FJ Kuo WW Chen LM Chih-Yang Huang

Zanthoxylum avicennae extracts inhibit cell proliferation through protein phosphatase 2A activation

in HA22T human hepatocellular carcinoma cells in vitro and in vivo Int J Mol Med 2012

Jun29(6)1045-52 (Correspondence Author)

38 Lin PP Hsieh YM Kuo WW Lin CC Tsai FJ Tsai CH Chih-Yang Huang Tsai CC Inhibition of

cardiac hypertrophy by probiotic-fermented purple sweet potato yogurt on spontaneously

hypertensive rat hearts Int J Mol Med 2012 Dec30(6)1365-75 (co-correspondence Author)

39 Chih-Yang Huang Yang AL Lin YM Wu FN Lin JA Chan YS Tsai FJ Tsai CH Kuo CH Lee

SD Anti-apoptotic and pro-survival effects of exercise training on hypertensive hearts J Appl

Physiol 2012 Mar112(5)883-91 (First Author)

40 Hsu HH Liu CJ Shen CY Chen YJ Chen LM Kuo WH Lin YM Chen RJ Tsai CH Tsai FJ 13

Chih-Yang Huang p38α MAPK Mediates 17β-Estradiol Inhibition of MMP-2 and -9

Expression and Cell Migration in Human LoVo Colon Cancer Cells J Cell Physiol 2012

Nov227(11)3648-60 (Correspondence Author)

41 Chih-Yang Huang Chien-Hsun Lin Tung-Tso Ho Hui-Chen Chen Mei-Yun Chu Wei-Shen Sun

Wei-Chien Kao Shan-hui Hsu Huey-Shan Hung Enhanced migration of Whartonrsquos jelly

mesenchymal stem cells grown on polyurethane nanocomposites Journal of Medical and Biological

Engineering 2012 in press (First Author)

42 Lee SD Shyu WC Cheng IS Kuo CH Chan YS Lin YM Tasi CY Tsai CH Ho TJ Chih-Yang

Huang Effects of exercise training on cardiac apoptosis in obese rats Nutr Metab Cardiovasc Dis

2012 Mar 6 [Epub ahead of print] (co-correspondence Author)

43 Chang WS Yang MD Tsai CW Cheng LH Jeng LB Lo WC Lin CH Chih-Yang Huang Bau DT

Association of Cyclooxygenase 2 Single Nucleotide Polymorphisms and Hepatocellular Carcinoma

in Taiwan Chin J Physiol 2012 Feb 2955(1)1-7 (co-correspondence Author)

44 Korivi M Hou CW Chih-Yang Huang Lee SD Hsu MF Yu SH Chen CY Liu YY Kuo CH

Ginsenoside-Rg1 Protects the Liver against Exhaustive Exercise-Induced Oxidative Stress in Rats

Evid Based Complement Alternat Med 2012 2012932165


CCN6 enhances ICAM-1 expression and cell motility in human chondrosarcoma cells Evid Based

Complement Alternat Med 2012 Jan227(1)223-32

46 Lin YM Su CC Su WW Hwang JM Hsu HH Tsai CH Wang YC Tsai FJ Chih-Yang Huang Liu

JY Chen LM Expression of protein kinase C isoforms in cancerous breast tissue and adjacent

normal breast tissue Chin J Physiol 2012 Feb 2955(1)55-61 (co-correspondence Author)

47 Chen FJ Wang HS Chih-Yang Huang Chen YS Pulse Analysis in Bipolar Disordered and

Nonpsychotic Human Subjects Am J Chin Med 2012 40(3)455-65

48 Chien-Yi Ho HM Liao Chih-Yen Tu Chih-Yang Huang Chuen-Ming Shih MY Su Chuen-Ming

Shih Tzu- ching Shih Numerical analysis of airflow alteration in central airways following

tracheobronchial stent placement Experimental Hematology amp Oncology 2012 Aug 271(1)23

49 Wu MH Lo JF Kuo CH Lin JA Lin YM Chen LM Tsai FJ Tsai CH Chih-Yang Huang Tang

CH Endothelin-1 promotes MMP-13 production and migration in human chondrosarcoma cells

through FAKPI3KAktmTOR pathways J Cell Physiol 2012 Aug227(8)3016-26



6-hydroxydopamine-induced cell death in dopaminergic-like MES235 cells J Cell Physiol 2013

Mar228(3)563-71

51 Ming-Chieh Wu Ying-Lan Tsai Chih-Yang Huang Chung-Lan Kao Chien-Wen Hou Chung-Yu

Chen Mallikarjuna Korivi Wei-Horng Jean Shin-Da Lee Chia-Hua Kuo Hyperinsulinemia and

overweight in obese Zucker rats effectively suppressed by exercise training withhypoxia recovery

European Journal of Sport Science 2012 At 1914

52 Ho TJ Huang CC Chih-Yang Huang Lin WT Eur J Appl Physiol Fasudila Rho-kinase

inhibitorprotects against excessive endurance exercise training-induced cardiac

hypertrophyapoptosis and fibrosis in rats Eur J Appl Physiol 2012 Aug112(8)2943-55


53 Ding-Yu Lin Fuu-Jen Tsai Chang-Hai Tsai Chih-Yang Huang Mechanisms governing the

protective effect of 17b-estradiol and estrogen receptors against cardiomyocyte injury BioMedicine

2012 (co-correspondence Author)

54 Cheng IS Huang SW Lu HC Wu CL Chu YC Lee SD Chih-Yang Huang Kuo CH Oral

hydroxycitrate supplementation enhances glycogen synthesis in exercised human skeletal muscle Br

J Nutr 2011 Apr107(7)1048-55 (co-correspondence Author)

55 Chung YS Chih-Yang Huang Ma MC Chu CC Chiang HS Lin LJ Chou SH Cardiac Injury

Protection from Mouse Bone Marrow Stromal Cells with In Utero Transplantation Followed by

Secondary Postnatal Boost Chin J Physiol 2011 Aug 3154(4)205-18

56 Hsu GJ Tzang BS Tsai CC Chiu CC Chih-Yang Huang Hsu TC Effects of Human Parvovirus

B19 on Expression of Defensins and Toll-Like Receptors CHINESE JOURNAL OF

PHYSIOLOGY 2011 Oct 3154(5)367-76 (co-correspondence Author)

57 Chang YM Chi WY Lai TY Chen YS Tsai FJ Tsai CH Kuo WW Cheng YC Lin CC Chih-Yang

Huang Dilong Role in Peripheral Nerve Regeneration Evid Based Complement Alternat Med

2011 2011380809 (co-correspondence Author)

58 Shen JL Chen YS Lin JY Tien YC Peng WH Kuo CH Tzang BS Wang HL Tsai FJ Chou MC

Chih-Yang Huang Lin CC Neuron Regeneration and Proliferation Effects of Danshen and

Tanshinone IIA Evid Based Complement Alternat Med 2011 2011378907 (co-correspondence

Author)

59 Tran Duc Dung Chih-Hsueh Lin Truong Viet Binh Hsi-Hsien Hsu Cheng-Chuan Su Yueh-Min Lin

Chang-Hai Tsai Fuu-Jen Tsai Wei-Wen Kuo Li-Mien Chen Chih-Yang Huang Diosmin induces

cell apoptosis through protein phosphatase 2A activation in HA22T human hepatocellular carcinoma

cells and blocks tumour growth in xenografted nude mice FOOD CHEMISTRY 2011


60 Ching-I Lin Wan-Teng Lin Ming-Jen Fan Ming-Chang Lin Chang-Hai Tsai Fuu-Jen Tsai Wei-Jen

Ting Chih-Yang Huang Ying-Lan Tsai Clinical Characteristics change and the Heart Rate

variability of Subjects with Metabolic Syndrome in the Weight Loss Program IEEE International

Conference on Bioinformatics and Bioengineering 2011 (co-correspondence Author)

61 Dung TD Chang HC Chen CY Peng WH Tsai CH Tsai FJ Kuo WW Chen LM Chih-Yang

Huang Zanthoxylum avicennae extracts induce cell apoptosis through protein phosphatase 2A

activation in HA22T human hepatocellular carcinoma cells and block tumor growth in xenografted

nude mice INTERNATIONAL JOURNAL OF MOLECULAR MEDICINE 2011

Dec28(6)927-36 (Correspondence Author)

62 Kuo MY Ou HC Lee WJ Kuo WW Hwang LL Song TY Chih-Yang HuangChiu TH Tsai KL

Tsai CS Sheu WH Ellagic Acid Inhibits Oxidized Low-Density Lipoprotein (OxLDL)-Induced

Metalloproteinase (MMP) Expression by Modulatingthe Protein Kinase C-rExtracellular

Signal-Regulated KinasePeroxisome Proliferator-Activated Receptor γNuclear

Factor-KB(PKC-rERKPP 2011 May 1159(9)5100-8

63 Hsu HH Hu WS Lin YM Kuo WW Chen LM Chen WK Hwang JM Tsai FJ Liu CJ Chih-Yang

Huang JNK suppression is essential for 17b-Estradiol inhibits prostaglandin E2-Induced uPA and

MMP-9 expressions and cell migration in human LoVo colon cancer cells 2011 Aug 221861


64 Chu CH Lo JF Hu WS Lu RB Chang MH Tsai FJ Tsai CH Weng YS Tzang BS Chih-Yang

Huang HistoneQ1 Acetylation Is Essential for ANG-II-Induced IGF-IIR Gene Expression in H9c2

Cardiomyoblast Cells and Pathologically Hypertensive Rat Heart J Cell Physiol 2011

Jan227(1)259-68 (Correspondence Author)

65 JUI-LUNG SHEN1TSAI-CHING HSU YI-CHEN CHEN JENG-DONG HSU LIEN-CHUAN

YANG FUU-JEN TSAI CHENG-CHIEN LI YA-WEN CHENG Chih-Yang Huang BOR-SHOW

TZANG EFFECTS OF DEEP-SEA WATER ON CARDIAC ABNORMALITY IN

HIGH-CHOLESTEROL DIETARY MICE Journal of Food Biochemistry 2011


66 Chen TS Liou SY Wu HC Tsai FJ Tsai CH Chih-Yang Huang Chang YL Efficacy of

Epigallocatechin-3-Gallate and Amla (Emblica officinalis) Extract for the Treatment of Uremic

Diabetic Patients J Med Food 2011 Jul-Aug14(7-8)718-23 (co-correspondence Author)

67 Lai TY Su CC Kuo WW Yeh YL Kuo WH Tsai FJ Tsai CH Weng YJ Chih-Yang Huang Chen

LM β-catenin plays a key role in metastasis of human hepatocellular carcinoma Oncol Rep 2011

Aug26(2)415-22 (co-correspondence Author)

68 Chiu YW Lin TH Huang WS Teng CY Liou YS Kuo WH Lin WL Huang HI Tung JN

Chih-Yang Huang Liu JY Wang WH Hwang JM Kuo HC Baicalein inhibits the migration and

invasive properties of human hepatoma cells Toxicol Appl Pharmacol 2011 Sep 15255(3)316-26

69 Lo JF Yu CC Chiou SH Chih-Yang Huang Jan CI Lin SC Liu CJ Hu WY Yu YH The

epithelial-mesenchymal transition mediator S100A4 maintains cancer-initiating cells in head and

neck cancers Cancer Res 2011 Mar 171(5)1912-23

70 Chen LM Kuo CH Lai TY Lin YM Su CC Hsu HH Tsai FJ Tsai CH Chih-Yang Huang Tang

CH RANKL increases migration of human lung cancer cells through intercellular adhesion

molecule-1 up-regulation J Cell Biochem 2011 Mar112(3)933-41 (Correspondence Author)

71 Chiang YF Shaw HM Yang MF Chih-Yang Huang Hsieh CH Chao PM Dietary oxidised frying

oil causes oxidative damage of pancreatic islets and impairment of insulin secretion effects

associated with vitamin E deficiency Br J Nutr 2011 May105(9)1311-9

72 Chih-Yang HuangYu HS Lai TY Yeh YL Su CC Hsu HH Tsai FJ Tsai CH Wu HC Tang CH

Leptin increases motility and integrin up-regulation in human prostate cancer cells J Cell Physiol

2011 May226(5)1274-82 (First Author)

73 Hseu YC Wu CR Chang HW Kumar KJ Lin MK Chen CS Cho HJ Chih-Yang Huang Huang

CY Lee HZ Hsieh WT Chung JG Wang HM Yang HL Inhibitory effects of Physalis angulata on

tumor metastasis and angiogenesis J Ethnopharmacol 2011 Jun 1135(3)762-71

74 Huang KS Lin JG Lee HC Tsai FJ Bau DT Chih-Yang Huang Yao CH Chen YS Paeoniae alba

Radix Promotes Peripheral Nerve Regeneration Evid Based Complement Alternat Med2011

2011109809

75 Tsai CY Lai CH Chang MH Jong GP Cheng YC Tsai FJ Tsai CH Kuo WH Hsieh DJ

Chih-Yang Huang IGF-II and MMP9 as surgical repair indicators of ventricular septal defects

Clin Chim Acta 2011 Apr 11412(9-10)761-5 (Correspondence Author)

76 Tien YC Liao JC Chiu CS Huang TH Chih-Yang Huang Chang WT Peng WH Esculetin

ameliorates carbon tetrachloride-mediated hepatic apoptosis in rats Int J Mol Sci 2011 in press

77 Jan CI Yu CC Hung MC Harn HJ Nieh S Lee HS Lou MA Wu YC Chen CY Chih-Yang

Huang Chen FN Lo JF Tid1 CHIP and ErbB2 interactions and their prognostic implications for

breast cancer patients J Pathol 2011 Nov225(3)424-37

78 Chen JL Yeh DP Lee JP Chen CY Chih-Yang Huang Lee SD Chen CC Kuo TB Kao CL Kuo

CH Parasympathetic nervous activity mirrors recovery status in weightlifting performance after

training J Strength Cond Res 2011 Jun25(6)1546-52

79 Bau DT Chang CH Tsai RY Wang HC Wang RF Tsai CW Yao CH Chen YS Shyue SK

Chih-Yang Huang Significant association of caveolin-1 genotypes with bladder cancer

susceptibility in Taiwan Chin J Physiol 2011 Jun 3054(3)153-60 (Correspondence Author)

80 Wang W 55 Chih-Yang Huang Tsai FJ Tsai CC Yao CH Chen YS Growth-promoting effects of

quercetin on peripheral nerves in rats Int J Artif Organs 2011 Nov34(11)1095-105

81 Chih-Yang Huang Yi-Fan Liou Shu-Ying Chung Peiying Pai Chung-Ben Kan Chia-Hua Kuo

Chang-Hai Tsai Jing-Ying Lin Role of ERK Signaling in the Neuroprotective Efficacy of

Magnesium Sulfate Treatment During Focal Cerebral Ischemia in the Gerbil Cortex CJP 2010 Oct

3153(5)299-309 (First Author)


Chang-Hai Tsai Jing-Ying Lin Magnesium sulphate enhanced the ischemia-induced glucose

transporter 3 expression in Gerbil brains without HIF-1α and ERK signalling pathway involved CBF

2010 (First Author)

83 Da-Tian Bau Hwei-Chung Wang

Chiu-Shong Liu

Chia-Lin Chang Su-Yin Chiang Rou-Fen

Wang Chia-Wen Tsai Yen-Li Lo Chao A Hsiung Cheng-Chieh Lin Chih-Yang Huang Single

Nucleotide Polymorphism of Exo1 Gene Association with Gastric Cancer Susceptibility and

Interaction with Smoking in Taiwan Chinese Journal of Physiology 2010 Dec 3152(6)411-8


84 Yung-Ming Chang Ying-Ting Shih Yueh-Sheng Chen Chien-Liang Liu Wen-Kuei

Fang Chang-Hai Tsai Fuu-Jen Tsai Wei-Wen Kuo Tung-Yuan Lai Chih-Yang Huang Schwann

cell migration induced by earthworm extract via activation of PAs and MMP29 mediated through

ERK12 and p38 ECAM 2010 2011395458 (Correspondence Author)

85 Yung-Ming Chang Wu-Hsien Kuo Tung-Yuan Lai Ying-Ting Shih Fuu-Jen Tsai Chang-Hai Tsai

Wen-Tong Shu Ying-Yu Chen Yueh-Sheng Chen Wei-Wen Kuo Chih-Yang Huang RSC96

Schwann cell proliferation and survival induced by Dilong through PI3KAkt signaling mediated by

IGF-I ECAM 2010 2011216148 (Correspondence Author)

86 Hsien-Tung Chen Bor-Show Tzang Yueh-Sheng Chen Kung-Wei Lee Wei-Kung Chen Hwai-Lee

Wang Fuu-Jen Tsai Chang-Hai Tsai Tung-Yuan Lai Ying-Lan Tsai Chih-Yang Huang

Chung-Yen Lu Dangshen (Codonopsis Pilosula) activates IGF-I and FGF-2 pathways to induce

Proliferation and Migration Effects in RSC96 Schwann Cells AJCM 2010 38(2)359-72


87 Wen-Kuei Fang Yi-Jiun Weng Mu-Hsin Chang Li-Mien Chen Yueh-Sheng Chen Hsi-Hsien Hsu

Fuu-Jen Tsai Chang-Hai Tsai Wu-Hsien Kuo Chih-Yang Huang Chung Yen Lu Proliferative

effects of chishao on injured peripheral neurons AJCM 2010 38(4)735-43 (co-correspondence

Author)

88 Wei-Hung Hsu Tsung-Jung Ho Chih-Yang HuangHsu-Chueh Ho Yi-Ling Liu Hsu-Jan Liu

Ning-Sheng Lai and Jung-Geng Acupoint herbal patch for allergic rhinitis a randomised controlled

trial AJCM 2010 38(4)661-73 (Co-first Author)

89 Wei-Wen Kuo Tsai-Ching Hsu Mei-Haung Chain Chao-Hung Lai Wen-Hong Wang Fuu-Jen Tsai

Chang-Hai Tsai Chieh-His Wu Chih-Yang Huang Bor-Show Tzang Attenuated the Cardiac

Mitochondrial-dependent Apoptotic effects by Li-Fu Formula in hamsters fed with a

hypercholesterol diet ECAM 2010 Article ID 530345 9 pages (co-correspondence Author)

90 Tsai-Ching Hsu Joung-Liang Lan Shao-Hsuan Kao Yin-Chang Liu Chih-Yang Huang

Bor-Show Tzang Identification of an Autoantibody against Proliferating Cell Nuclear Antigen from

a Patient with Systemic Lupus Erythematosus CJP 2010 Feb 2853(1)11-8 (co-correspondence

Author)

91 Sheen-Yie Fang Diahn-Warng Perng J Yu-Yun Lee Ding-Yu Lin Chih-Yang Huang A

Open-Label Multicentre Study of Levocetirizine for the Treatment of Allergic Rhinitis and Urticaria

in Taiwanese Patients CJP 2010 Aug 3153(4)199-207 (Correspondence Author)

92 Shiung Cheng Su-Fen Liao Kai-Li Liu Hsin-Yi Liu Ching-Lin Wu Chih-Yang Huang

Mallikarjuna K Richard William Smith Chia-Hua Ku Effect of Dietary Glycemic Index on

Substrate Transporter Gene Expression in Human Skeletal Muscle Following Exercise EJCN 2009

Dec63(12)1404-10

93 Chien-Chung Lin Min-Ting Tsai Wei-Wen Su Li-Ming Chen MD Tung-Yuan Lai Jin-Ming

Hwang Hsi-Hsien Hsu Shiow-Kang Yen Chih-Yang Huang and Jer-Yuh Liu Protein kinase C

alpha location and the expression of phospho-MEK and MDR1 in hepatitis virus-related

hepatocellular carcinoma biopsies CJP 2010 Apr 3053(2)112-8 (co-correspondence Author)

94 Eric YC LAI Yi-jiun WENG Wei-wen KUO Li-mien CHEN Yun-ting CHUNG Yueh-min LIN

Fuu-jen TSAI Chun-hsin LEE Tung-yuan LAI Chih-Yang HUANG Yu-lan YEH Taohe

ChengQi Tang ameliorated the acute liver injury induced by carbontetrachloride (CCl4) in rats

Journal of Chinese Integrative Medicine (JCIM) 2010 Jan8(1)49-55 (co-correspondence Author)

95 Chi-Yuan Chen Shih-Hwa Chiou Chih-Yang Huang Chia-Ing Jan Su-Chun Lin Ming-Long Tsai

and Jeng-Fan Lo The establishment of a highly malignant human head and neck squamous cell

carcinoma cell line using a xenograft model JBS 2010

96 Chi-Yuan Chen Shih-Hwa Chiou Chih-Yang Huang Chia-Ing Jan Su-Chun Lin Wen-Yuan Hu

Shiu-Huey Chou Chung-Ji Liu Jeng-Fan Lo Tid1 Attenuates EGFRPI3KAKT Signaling and

Reduces Head and Neck Squamous Cell Carcinoma Malignancy J of Pathology 2010

Nov219(3)347-55

97 Hwei-Chung Wang Chiu-Shong Liu Chung-Hsing Wang Chia-Ling Chang Chia-Wen Tsai

Rou-Fen Wang Chao-Hsiang Chang Yueh-Sheng Chen Chang-Fang Chiu Da-Tian Bau

and

Chih-Yang Huang Significant Association of XPD Asp312Asn Polymorphism with Breast

Cancer in Taiwanese Patients CJP 2010 Apr 3053(2)130-5 (Correspondence Author)

--------------------------------------------------------------------------------------------------------------------------------

98 Chung-Jung Liu Jeng-Fan Lo Chia-Hua Kuo Chun-Hsien Chu Li-Ming Chen Fuu-Jen Tsai

Chang-Hai Tsai Bor-Show Tzang Wei-Wen Kuo and Chih-Yang Huang Akt Mediates

17β-Estradiol andor Estrogen Receptor Inhibition of LPS-Induced Tumor Necrosis

Factor-αExpression and Myocardial Cell Apoptosis by Suppressing the JNK12 and NFkB Pathway

2009 J of Cellular and Molecular Medicine Sep13(9B)3655-67 (Correspondence Author)

99 Chun-Hsien Chu Bor-Show Tzang Li-Mien Chen Chung-Jung Liu Fuu-Jen Tsai Chang-Hai Tsai

James A Lin Da-Tian Bau Chun-Hsu Yao Chih-Yang Huang Specific Activated IGF2R

Induces Mitochondria-dependent Apoptosis through Gαq and Downstream Calcineurin Signaling in

Myocardial Cells Endocrinology 2009 Jun150(6)2723-31 (Correspondence Author)

100 Chen KY Liao WJ Kuo SM Tsai FJ Chen YS Huang CY Yao CH Asymmetric chitosan

membrane containing collagen I nanospheres for skin tissue engineering Biomacromolecules 2009

Jun 810(6)1642-9 (co-correspondence Author)

101 Ray-Jade Chen Wei-Wen Kuo Mu-Hsin Chang Chao-Hung Lai Jin-Ming Hwang Wu-Hsien Kuo

Fuu-Jen Tsai Chang-Hai Tsai Li-Mien Chen Chih-Yang Huang Chun-Hsien Chu Leu27IGF-II

plays opposite role with IGF-I to induce H9c2 cardiomyoblast cell apoptosis via Gαq signaling J

Mol Endocrinol 2009 (Co-correspondence Author)

102 Chih-Yang Huang Li-Chiu Yang Kuan-Yu Liu Pao-Hsin Liao Liao Janet Ing-Yuh Chou

Ming-Yung Chou Wei-Wen Lin and Jaw-Ji Yang RhoGDIbeta-induced hypertrophic growth in

H9c2 cells is negatively regulated by ZAK Journal of Biomedical Science 2009 Jan

221611(First Author)

103 Chih-Yang Huang Li-Chiu Yang Kuan-Yu Liu Pao-Hsin Liao Janet Ing-Yuh Chou Ming-Yung

Chou Wei-Wen Lin and Jaw-Ji Yang ZAK negatively regulates RhoGDIβ-induced Rac1-mediated

hypertrophic growth and cell migration Journal of Biomedical Science 2009 Jun 181656 (First

Author)

104 Yi-Chang Cheng Li-Mien Chen Mu-Hsin Chang Wei-Kung Chen Fuu-Jen Tsai Chang-Hai Tsai

Yi-Chang Cheng Wei-Wen Kuo and Chih-Yang Huang Chung-Jung Liu

Lipopolysaccharide-Upregulated uPA MMP-2 and MMP-9 via ERK12 signaling in H9c2

Cardiomyoblast Cells Mol Cell Biochem 2009 (co-Correspondence Author)

105 Yi-Chang Cheng Wei-Wen Kuo Hsi-Chin Wu Tung-Yuan Lai Jin-Ming Hwang Wen-Hung Wang

Fuu-Jen Tsai Jaw-Ji Yang Chih-Yang Huang Chun-Hsien Chu ZAK induces MMP-2 activity

via JNK p38 signals and reduces MMP-9 activity by increasing TIMP-12 expression in H9c2

cardiomyoblast cells Mol Cell Biochem2009 May325(1-2)69-77 (co-Correspondence Author)

106 Kun-Shan Huang Jaung-Geng Lin Han-Chung Lee Fuu-Jen Tsai Da-Tian Bau Chih-Yang

Huang Chun-Hsu Yao Yueh-Sheng Chen Paeoniae alba Radix promotes peripheral nerve

regeneration Evidence Based Complementary and Alternative Medicine 2009


107 Lin WY Pi-Sunyer FX Liu CS Li TC Li CI Huang CY Lin CC Betel nut chewing is strongly

associated with general and central obesity in Chinese male middle-aged adults Obesity (Silver

Spring) 2009 Jun17(6)1247-54


Fang Chang-Hai Tsai Fuu-Jen Tsai Wei-Wen Kuo Tung-Yuan Lai Chih-Yang Huang

Earthworm (Pheretima aspergilum) extracts to induce the Schwann cell migration activate PAs and

MMP29 mediated through ERK12 and p38 signalings ECAM Journal 2009 Oct 3152(5)306-15


109 Wang JS Chen SM Lee SP Lee SD Huang CY Hsieh CC Kuo CH Dehydroepiandrosterone

Sulfate Linked to Physiologic Response against Hot Spring ImmersionSteroids 2009 Jul 9

110 Chen YL Huang CY Lee SD Chou SW Hsieh PS Hsieh CC Huang YG Kuo CH

Discipline-specific insulin sensitivity in athletes Nutrition 2009 Jul 11

111 Wei-Wen Kuo Min-Jin Lu Cheng-Tzu Liu Shih-Ping Wu Chia-Hua Kuo Fuu-Jen Tsai Chang-Hai

Tsai Hung-Chien Wu Chih-Yang HuangShin-Da Lee Effects of insulin replacement on

cardiac apoptotic and survival pathways in streptozotocin-induced diabetic rats Cell Biochemistry

and Function 2009 (co-correspondence Author)

112 Chun-Hsien Chu Chih-Yang Huang Ming-Chin Lu James A Lin Fuu-Jen Tsai Chang-Hai

Tsai Chia-Yih Chu Wu-Hsien Kuo Li-Mien Chenand Ling-Yun Chen Enhancement of

AG1024-Induced H9c2 Cardiomyoblast Cell Apoptosis via the Interaction of IGF2R with Gα

Proteins and Its Downstream PKA and PLC-β Modulators by 1GF-II Chinese Journal of

Physiology 52(1) 1-7 2009 (co-First Author)

113 Chen CH Liu YF Lee SD Huang CY Lee WC Tsai YL Hou CW Chan YS Kuo CH Altitude

hypoxia increases glucose uptake in human heart High Alt Med Biol 2009 Spring10(1)83-6

114 Ming-Chin Lu Tung-Yuan Lai Jin-Ming Hwang Hsien-Te Chen3 Sheng-Huang

Chang Fuu-Jen Tsai Hwai-Lee Wang Chien-Chung Lin Wei-Wen Kuo Chih-Yang Huang

Proliferation- and migration- enhancing effects of Ginseng and Ginsenoside Rg1 through IGF-I- and

FGF-2-signaling pathways on RSC96 Schwann Cells (Cell Biochemistry and Function 2009 in

press (Correspondence Author)

115 Kun Shan Huang Min-Jin Lu Yueh-Sheng Chen Fuu-Jen Tsai Wei-Wen Kuo Yi-Chang Cheng

Chien-Chung Lin Chang-Hai Tsai Chih-Yang Huang Jaung-Geng Lin Hsiu-Chung Ou

Proliferative effects of chishao on Schwann cells are FGF-uPA and ERK- and JNK-dependent

American J of Chinese Medicine 2009 in press (co-Correspondence Author)

116 Wen-Kuei Fang Fu-Yang Ko Hwai Lee Wang Ming-Chin Lu Li-Ming Chen Fuu-Jen Tsai

Chang-Hai Tsai Yueh-Sheng Chen Wei-Wen Kuo Chih-Yang Huang The Proliferate and Migrate

Effects of Huangqi On RSC96 Schwann Cells American J of Chinese Medicine 2009 in press


117 Chih-Yang Huang Tsai-Ching Hsu Wu-Hsien Kuo Shih-Ping Wu Yueh-Min Lin Chun-Yu Yen

Jen-Huang Wu Bor-Show Tzang Beneficial Effects of Taurine on Cardiac Abnormality in NZBW

F1 Mice Fed with a High-Cholesterol Diet Journal of Agricultural and Food Chemistry 2009 (First

Author)

118 Wei-Wen Kuo Chih-Yang Huang Jing-Gung Chung Shun-Fa Yang Kun-Ling Tsai Tsan-Hung

Chiu Shin-Da Lee Hsiu-Chung Ou Journal of Vascular Surgery 2009

119 Lin WT Huang CC Lin TJ Chen JR Shieh MJ Peng HC Yang SC Huang CY Effects of

beta-carotene on antioxidant status in rats with chronic alcohol consumption Cell Biochem Funct

2009 Jul 27 (co-correspondence Author)

120 Chi-Chang Huang Tien-Jen Lin Yi-Fa Lu Chun-Chieh Chen Chih-Yang Huang Wan-Teng Lin

Protective Effects of L-Arginine Supplementation Against Exhaustive Exercise-Induced Oxidative

Stress in Young Rat Tissue (Chinese Journal of Physiology 2009 in press (Co-Correspondence

Author)


Bor-Show Tzang Character of Autoantibody against Proliferating Cell Nuclear Antigen from a

Patient with Systemic Lupus Erythematosus The Chinese Journal of Physiology 2009

Feb79(2)209-14 (co-correspondence Author)

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122 Shin-Da Lee Wei-Wen Kuo Da-Tian Bau Fu-Yang Ko Fong-Li Wu Chia-Hua Kuo Jin-Ming

Hwang Shyi-Gang P Wang Min-Chi Lu Chih-Yang Huang The coexistence of intermittent

hypoxia and obesity additively increase cardiac apoptosis (Journal of Applied Physiology 2008

Apr104(4)1144-53 (Correspondence Author)

123 Chiou SH CC Yu CY Huang SC Lin

CJ Liu TH Tsai SH Chou CS Chien HH Ku JF

Lo Positive Correlations of Oct-4 and Nanog in Oral Cancer Stem-Like Cells and High Grade Oral

Squamous Cell Carcinoma Clinical Cancer Research 2008 Jul 114(13)4085-95

124 Tseng HC Tsai MH Chiu CF Wang CH Chang NW Huang CY Tsai CW Liang SY Wang CL

Bau DT Association of XRCC4 codon 247 polymorphism with oral cancer susceptibility in Taiwan

Anticancer Res 2008 28(3A)1687-91

125 Tsai-Ching Hsu Yi-Chen Chen Wen-Xian Lai Szu-Yi Chiang Chih-Yang Huang Bor-Show

Tzang Beneficial effects of treatment with cystamine on brain in NZBW F1 mice European

Journal of Pharmacology 2008591307-314 (Co-correspondence Author)

126 Tsai-Ching Hsu Szu-Yi Chiang Jen-Huang Wu Chun-Chou Tsai Chih-Yang HuangYi-Chen Chen

Bor-Show Tzang Treatment with Taurine Attenuates Hepatic Apoptosis in NZBW F1 Mice Fed with

a High-Cholesterol Diet J Agric Food Chem September 25 2008 56(20)9685-9691

(Co-correspondence Author)

127 Yi-Chang Cheng Wei-Wen Kuo Chieh-Hsi Wu Wen-Tong Shu Chia-Hua Kuo Jin-Ming Hwang

Hsi-Hsien Hsu Li-Ming Chen Chih-Yang Huang

Shin-Da Lee PhD

Iron status and

cardiovascular risk factors in patients with hemodialysis versus patients with ischemic heart disease

Nephrology 2008 Feb14(1)65-9 (Co-correspondence Author)

128 Shin-Da Lee Wei-Wen Kuo Ying-Jui Ho Ann-Chi Lin Chang-Hai Tsai Hsueh Fang Wang

Chia-Hua Kuo Ai-Lun Yang Chih-Yang Huang

Jin-Ming Hwang

Cardiac Fas-dependent and

mitochondria-dependent apoptosis in ovariectomized rat2008 61(3)268-277 (Co-correspondence

Author)

129 Chun-Hsien Chu Chih-Yang Huang Ming-Chin Lu James A Lin Fuu-Jen Tsai Chang-Hai Tsai

Chia-Yih Chu Wu-Hsien Kuo Li-Mien Chen Ling-Yun Chen IGF-II Synergistically Enhances

AG1024-induced H9c2 Cardiomyoblast Cell Apoptosis via the Interaction of IGF2R with Gα

Proteins and Its Downstream PKA and PLC-β Modulators (Chinese Journal of Physiology 2008

Feb 2852(1)31-7(Co-First Author)

130 Chung-Jung LiuYi-Chang ChengKung-Wei LeeHsi-Hsien HsuChun-Hsien Chu Fuu-Jen Tsai

Chang-Hai Tsai Chia-Yih Chu Jer-Yuh Liu Wei-Wen Kuo and Chih-Yang Huang

Lipopolysaccharide induces cellular hypertrophy through calcineurinNFAT-3 signaling pathway in

H9c2 myocardiac cells Mol Cell Biochem2008313(1-2)167-78 (Correspondence Author)

131 Chang MH Kuo WW Chen RJ Lu MC Tsai FJ Kuo WH Chen LY Wu WJ Huang CY Chu CH

IGF-IImannose 6-phosphate receptor activation induces metalloproteinase-9 matrix activity and

increases plasminogen activator expression in H9c2 cardiomyoblast cells J Mol Endocrinol 2008

41(2)65-74 (Co-correspondence Author)

132 Wen-Yuan Lin Tai-Yuan Chiu Long-Teng Lee Cheng-Chieh Lin Chih-Yang Huang and Kuo-Chin

Huang Betel nut chewing is associated with increased risk of cardiovascular disease and all-cause

mortality in Taiwanese men American Journal of Clinical Nutrition 200887(5) 1204-1211

133 Chun-Hsien Chu Bor-Show Tzang Li-Mien Chen Chia-Hua Kuo Yi-Chang Cheng Ling-Yun Chen

Fuu-Jen Tsai Chang-Hai Tsai Wei-Wen Kuo Chih-Yang Huang IGF-II receptor signaling

induced cell hypertrophy and ANPBNP expression via Gαq interaction and PKCα CaMKII

activation in the H9c2 cardiomyoblast cells (Journal of Endocrinology 2008 197(2)381-390 )


134 Tsai JH Liu JY Wu TT Ho PC Huang CY Shyu JC Hsieh YS Tsai CC and Liu YC

Effects of silymarin on the resolution of liver fibrosis induced by carbon tetrachloride in rats Journal

of Viral Hepatitis 2008 Jul15(7)508-14 SCI

135 Wei-Wen Kuo Chung-Jung Liu Chun-Hsien Chu Yi-Jiun Weng May-Hua Jen Ming-Chin Lu

Fuu-Jen Tsai Chang-Hai Tsai and Chih-Yang Huang A Phonex Arising From Fire New

Application of Old Traditional herbs Chapter 6 Traditional Chinese Medicine on Protection of Heart

Function and Cardiovascular System Research Signpost 2008 (Correspondence Author)

136 Te-Chi Liu Yung-Yang Liu Shin-Dd Lee Chih-Yang Huang Kuei-Yu Chien I-Shiung Cheng

Chih-Yuan Lin Chia-Hua Kuo Effects of short-term detraining on measures of obesity and glucose

tolerance in elite athletes Journal of Sports Sciences 2008 26(9) 919-925 SCI

137 Tsai-Ching Hsu Ji-Qiang Gao Ko-Hsiu Lu Chang-Hai Tsai Chih-Yang Huang Bor-Show

Tzang Japanese Encephalitis Virus Envelope Protein Mitigates TNF-α mRNA Expression in

RAW2647 Cells Inflammation 200831(2)133-140 SCI (Co-correspondence Author)

138 Hsu TC Huang CY Chiang SY Lai WX Tsai CH Tzang BS Transglutaminase inhibitor cystamine

alleviates the abnormality in liver from NZBW F1 mice Eur J Pharmacol 2008579(1-3)382-389

139 Hsi-Chin Wu Yu-Lan Yeh Wei-Wen Kuo Shu-Kuei Huang Wu-Hsien Kuo Dennis Jine-Yuan

Hsieh Ching-Lin Wu Chang-Hai Tsai Shin-Da Lee Chih-Yang Huang P38 mitogen-activated

protein kinase pathways are involved in the hypertrophy and apoptosis of cardiomyocytes induced by

Porphyromonas gingivalis conditioned medium (Cell Biochemistry and Function 2008

26(2)246-255) (Correspondence Author)

140 Mei-Kuei Wu Chih-Yang Huang Ying Jay Liou Chin-Kun Wang Shin-Da Lee Glucose-insulin

homeostasis lipid profiles and GH-IGF-IGFBP axis in clozapine-treated schizophrenic obesity

versus non-psychiatric obesity (International Journal of Obesity 2008

141 Yueh-Min Lin Shu-Kuei Huang Hsueh Fang Wang Li-Mien Chen Fuu-Jen Tsai Hsi-Hsien Hsu

Chia-Hua Kuo Shyi-Gang P Wang Chih-Yang Huang Shin-Da Lee Short-Term versus

Long-Term Intermittent Hypobaric Hypoxia on Cardiac fibrosis and Fas-Death-Receptor Dependent

Apoptotic Pathway in Rat Hearts (Chinese Journal of Physiology 2008 51(5)308-316

(Co-Correspondence Author)

142 Chung-Jung Liu Jin-Ming Hwang Trang-Tiau Wu Yi-Hsien Hsieh Cheng-Chung Wu Yih-Shou

Hsieh Chang-Hai Tsai Hsi-Chin Wu Chih-Yang Huang and Jer-Yuh Liu Anion Exchanger

Inhibitor DIDS Induces Human Higher Maligant Hepatoccellular Carcinoma HA22T Cell Apoptosis

Moelcular and cellular Biochemistry 2008308(1-2)117-125 (Co-Correspondence Author)

143 Hui-Man Cheng Chien-Yun Hsiang Guang-Wei Chen Shih-Lu Wu Jaw-Chyun Chen Chih-Yang

Huang Da-Tian Bau Tin-Yun Ho LPS-Induced Interleukin-1α and TNF-αProduction is

inhibited by Menthone through NF-kB signaling Pathway in HaCat Cells Chinese Journal of

Physiology 200851(4)1-7

144 Jin-Ming Hwang Yi-Jiun Weng Yueh-Min Lin Da-Tian Bau Fu-Yang Ko Fuu-Jen Tsai Chieh-Hsi

Wu Pei-Cheng Lin Chih-Yang Huang Wei-Wen Kuo Hypoxia-induced compensatory effect as

related to Shh and HIF-1α in ischemia embryo rat heart Moelcular and cellular Biochemistry 2008

311(1-2)179-187 (Co-Correspondence Author)

--------------------------------------------------------------------------------------------------------

姓名黃志揚教授 Chih-Yang Huang

研究方向心臟分子生化及癌症分子醫學

研究室分子醫學研究室

學校(04-22053366)分機(O)3313 (L)3315 3316

醫院(04-22052121)分機(O)7716 7701 (L)7707

亞洲大學 04-23323456 分機(O)6140

E-mailcyhuangmailcmuedutw or cyhuangasiaedutw

現職 | 學歷 | 經歷 | 專長 | 榮譽 | 研究方向 | 合作實驗室 | 研究室成員 |

| 學術論文及著作 |

【現職】

亞洲大學生科系特聘教授兼研發處研發長

中國醫藥大學暨附設醫院桂冠研究人才計畫主持人

中國附醫醫學研究部 (顧問)

中國醫藥大學醫學院中醫學院共同實驗室負責人

中國醫藥大學基醫所中醫所臨醫所合聘教授

中醫大 BioMedicine 醫學雜誌副總編輯中國生理學雜誌(CJP SCI)及調適醫學雜誌編輯

國科會生物處專題研究計畫初複審委員及考選部高考出題審題委員

弘光科技大學營養醫學研究所兼任教授

【學歷】

國立陽明大學生理所心臟內分泌學碩士(1987-1989)

美國伊利諾大學香檳校區分子生理所乳癌分子醫學碩士(1992-1995)

美國伊利諾大學香檳校區分子生理所心臟分子醫學博士(1995-1998)

美國伊利諾大學香檳校區分子生理所心臟分子醫學博士後研究(1998-1999)

【經歷】

國立陽明大學生理學兼任助教(1987-1989)

中華民國國軍 39 期預官(醫勤官兼 333 師營站主任)(1989-1991)

美國伊利諾大學香檳校區分子生理所助理及助教(1992-1996amp1996-1998)

國立中正大學分子生物研究所兼任教授(2000-2008)

中山醫學大學生化暨生物科技研究所助教授(19998-20027)

中山醫學大學生化暨生物科技研究所副教授(20028-200510)

中山醫學大學生化暨生物科技研究所教授(200510-20067)

中山醫學大學創新育成中心主任(20058-20067)

中國醫藥大學基礎醫學研究所所長(200611-20131)兼副研發長(20098-20131)

中國生理學雜誌(CJP SCI)暨中醫大中台灣醫學雜誌副總編輯(20098-20131)

【榮譽】













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Iron status and





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Mar228(3)563-71



























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2011109809




















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Iron status and





Jin-Ming Hwang



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Iron status and





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Alternat Med 2012 2012736752











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Mar228(3)563-71



























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Iron status and





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-------------------------------------------------------------------------------------------------------------------------------





















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Iron status and





Jin-Ming Hwang



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Mar228(3)563-71



























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Dec63(12)1404-10















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-------------------------------------------------------------------------------------------------------------------------------





















Shin-Da Lee PhD

Iron status and





Jin-Ming Hwang



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Mar228(3)563-71



























Author)





















































2011 May226(5)1274-82 (First Author)






2011109809




















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2010 (First Author)


Chiu-Shong Liu






















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Dec63(12)1404-10















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Author)















Spring) 2009 Jun17(6)1247-54





































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Author)





-------------------------------------------------------------------------------------------------------------------------------





















Shin-Da Lee PhD

Iron status and





Jin-Ming Hwang



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2011 May226(5)1274-82 (First Author)






2011109809




















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Dec63(12)1404-10















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-------------------------------------------------------------------------------------------------------------------------------





















Shin-Da Lee PhD

Iron status and





Jin-Ming Hwang



Author)






























































--------------------------------------------------------------------------------------------------------












2011 May226(5)1274-82 (First Author)






2011109809




















3153(5)299-309 (First Author)




2010 (First Author)


Chiu-Shong Liu






















Author)











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Dec63(12)1404-10















Nov219(3)347-55



and



--------------------------------------------------------------------------------------------------------------------------------
























Author)















Spring) 2009 Jun17(6)1247-54





































Author)









Author)





-------------------------------------------------------------------------------------------------------------------------------





















Shin-Da Lee PhD

Iron status and





Jin-Ming Hwang



Author)






























































--------------------------------------------------------------------------------------------------------














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Dec63(12)1404-10















Nov219(3)347-55



and



--------------------------------------------------------------------------------------------------------------------------------
























Author)















Spring) 2009 Jun17(6)1247-54





































Author)









Author)





-------------------------------------------------------------------------------------------------------------------------------





















Shin-Da Lee PhD

Iron status and





Jin-Ming Hwang



Author)






























































--------------------------------------------------------------------------------------------------------

--------------------------------------------------------------------------------------------------------------------------------
























Author)















Spring) 2009 Jun17(6)1247-54





































Author)









Author)





-------------------------------------------------------------------------------------------------------------------------------





















Shin-Da Lee PhD

Iron status and





Jin-Ming Hwang



Author)






























































--------------------------------------------------------------------------------------------------------



























Author)









Author)





-------------------------------------------------------------------------------------------------------------------------------





















Shin-Da Lee PhD

Iron status and





Jin-Ming Hwang



Author)






























































--------------------------------------------------------------------------------------------------------











Shin-Da Lee PhD

Iron status and





Jin-Ming Hwang



Author)






























































--------------------------------------------------------------------------------------------------------




























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Documents

【黃志揚博士簡介】cmucms.cmu.edu.tw/huang1020521.pdf · 第27屆(2012年)生醫聯合學術年會壁報論文競賽生化分生組獲得優勝(賴益平) 第28屆(2013年)生醫聯合學術年會看板論文競賽生理組榮獲第三名(林依霖);