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NATURE MEDICINE VOLUME 10 | NUMBER 7 | JULY 2004 755 ERRATA ERRATUM: GC-1 promotes insulin resistance in liver through PPAR-α-dependent induction of TRB-3 Seung-Hoi Koo, Hiroaki Satoh, Stephan Herzig, Chih-Hao Lee, Susan Hedrick, Rohit Kulkarni, Ronald M Evans, Jerrold Olefsky & Marc Montminy Nature Medicine 10, 530-534 (2004) In the version of this article initially published online, the legend descriptions of Figure 3a and e were incorrect. They should read “(a) Western blot analysis of PGC-1, TRB-3 and Hsp-90 from fasted livers of diabetic mice injected with either GFP or PGC-1 RNAi adenovirus.” and “(e) Western blot analysis of PGC-1,TRB-3 and Hsp-90 in livers of 6 h fasted PPAR-α-deficient mice injected with either GFP or PGC-1 RNAi adenovirus.”, respectively. In addition, Figure 3b con- tained an incorrect label (“PGC-1 RNAi”); the corrected version of the panel is shown to the right. 0 1 2 3 4 C G/D GFP G/D/ins PGC-1 PGC-1 Relative mRNA level ERRATUM: Reciprocal CD40 signals through p38MAPK and ERK-1/2 induce counteracting immune responses Ram Kumar Mathur, Amit Awasthi, Pallavi Wadhone, Boppana Ramanamurthy & Bhaskar Saha Nat. Med. 10, 540-544 (2004) In the version of this article originally published online, labels at the right side of Figures 2 were cut off. In Figure 2d, the labels should read (top to bottom) "IL-12" "IL-10", and "DHFR"; in Figure 2h, the labels should read (top to bottom) "IL-10", "IL-12", "iNOS-2" and "DHFR". The complete version of both panels are shown to the right. In addition, the units for values reported in Figure 3g, lanes 4–6, were incorrectly listed as mmol (millimolar). The correct units should be µmol (micromolar). d IL-12 IL-10 DHFR Ladder Medium α-CD40 PD 25 µM PD 50 µM PD 100 µM SB 2 µg/ml SB 4 µg/ml SB 8 µg/m l α-CD40 (3 µg/ml) + Ladder Medium α-CD40 SB 2 µg/m l SB 4 µg/m l SB 8 µg/m l PD 25 µM PD 50 µM PD 100 µM α-CD40 (3 µ g/ml) + Uninfected macrophages Infected macrophages Ladder Medium α-CD40 Pep-I: 40 µM Pep-II: 20 µM Pep-I: 40 µM + Pep-II: 20 µM Medium α-CD40 Pep-I: 40 µM Pep-II: 20 µM Pep-I: 40 µM + Pep-II: 20 µM IL-10 IL-12 iNOS-2 DHFR α−CD40 α-CD40 Uninfected Infected h ERRATUM: Initiation of neuropathic pain requires lysophosphatidic acid receptor signaling Makoto Inoue, Md Harunor Rashid, Ryousuke Fujita, James J A Contos, Jerold Chun & Hiroshi Ueda Nat. Med. 10, 712-718 (2004) In the version of this article initially published online, on p. 715, at the beginning of the second column, the antisense oligonucleotide was identified incorrectly. The first complete sentence of the column should begin,“Moreover, preinjury injection with LPA1 AS-ODN...” In addition, the bottom curve in Figure 2c was labeled incorrectly. The label should read “Wild-type”. The corrected figure panel is printed to the right. © 2004 Nature Publishing Group http://www.nature.com/naturemedicine

ERRATUM: Reciprocal CD40 signals through p38MAPK and ERK-1/2 induce counteracting immune responses

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Page 1: ERRATUM: Reciprocal CD40 signals through p38MAPK and ERK-1/2 induce counteracting immune responses

NATURE MEDICINE VOLUME 10 | NUMBER 7 | JULY 2004 755

E R R ATA

ERRATUM: GC-1 promotes insulin resistance in liver through PPAR-α-dependent induction of TRB-3Seung-Hoi Koo, Hiroaki Satoh, Stephan Herzig, Chih-Hao Lee, Susan Hedrick, Rohit Kulkarni, Ronald M Evans, Jerrold Olefsky & Marc MontminyNature Medicine 10, 530-534 (2004)

In the version of this article initially published online, the legend descriptions of Figure 3a and ewere incorrect. They should read “(a) Western blot analysis of PGC-1, TRB-3 and Hsp-90 fromfasted livers of diabetic mice injected with either GFP or PGC-1 RNAi adenovirus.” and “(e)Western blot analysis of PGC-1, TRB-3 and Hsp-90 in livers of 6 h fasted PPAR-α-deficient miceinjected with either GFP or PGC-1 RNAi adenovirus.”, respectively. In addition, Figure 3b con-tained an incorrect label (“PGC-1 RNAi”); the corrected version of the panel is shown to the right. 0

1

2

3

4

C G/D

GFP

G/D/ins PGC-1

PGC-1

Rel

ativ

e m

RN

A le

vel

ERRATUM: Reciprocal CD40 signals through p38MAPK and ERK-1/2induce counteracting immune responsesRam Kumar Mathur, Amit Awasthi, Pallavi Wadhone, Boppana Ramanamurthy & Bhaskar SahaNat. Med. 10, 540-544 (2004)

In the version of this article originally published online, labels atthe right side of Figures 2 were cut off. In Figure 2d, the labelsshould read (top to bottom) "IL-12" "IL-10", and "DHFR"; inFigure 2h, the labels should read (top to bottom) "IL-10", "IL-12","iNOS-2" and "DHFR". The complete version of both panels areshown to the right.

In addition, the units for values reported in Figure 3g, lanes 4–6, were incorrectly listed as mmol (millimolar). The correct units should be µmol(micromolar).

d

IL-12

IL-10

DHFR

Ladd

er

Med

ium

α-C

D40

PD

25

µMP

D 5

0 µM

PD

100

µM

SB

2 µ

g/m

l

SB

4 µ

g/m

l

SB

8 µ

g/m

l

α-CD40 (3 µg/ml) +

Ladd

er

Med

ium

α-C

D40

SB

2

µg/ml

SB

4

µg/ml

SB

8

µg/ml

PD

25

µMP

D 5

0 µM

PD

100

µM

α-CD40 (3 µg/ml) +

Uninfected macrophages Infected macrophages

Ladd

erM

ediu

mα-

CD

40P

ep-I

: 40

µMP

ep-I

I: 20

µM

Pep

-I: 4

0 µM

+ P

ep-I

I: 20

µM

Med

ium

α-C

D40

Pep

-I: 4

0 µM

Pep

-II:

20 µ

MP

ep-I

: 40

µM +

Pep

-II:

20 µ

M

IL-10IL-12iNOS-2DHFR

α−CD40 α-CD40Uninfected Infected h

ERRATUM: Initiation of neuropathic pain requires lysophosphatidic acidreceptor signalingMakoto Inoue, Md Harunor Rashid, Ryousuke Fujita, James J A Contos, Jerold Chun & Hiroshi UedaNat. Med. 10, 712-718 (2004)

In the version of this article initially published online, on p. 715, at the beginning of the second column,the antisense oligonucleotide was identified incorrectly. The first complete sentence of the columnshould begin,“Moreover, preinjury injection with LPA1 AS-ODN...”

In addition, the bottom curve in Figure 2c was labeled incorrectly. The label should read “Wild-type”.The corrected figure panel is printed to the right.

©20

04 N

atur

e P

ublis

hing

Gro

up

http

://w

ww

.nat

ure.

com

/nat

urem

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ine