Presenter ： Yu-Hsiang Yen

Advisior ： Dr. Chun-Ju Hou

Date ： 2013.10.23

Establishment of Analysis System for Sleep Respiratory Activities

睡眠呼吸活動分析系統之建立

OutlineOutlineProblems and RationalePurpose and Specific AimsBackground and Literatures ReviewMaterials and MethodsPreliminary ResultsReferencesFuture Work

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Problems and RationaleSleep disorders

Taiwan Society of Sleep Medicine (2013)

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Problems and RationaleSleep Apnea

Obstructive Sleep Apnea(OSA)Central Sleep Apnea(CSA)Mixed Sleep Apnea(MSA)

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Problems and RationaleSymptom of Sleep Apnea

Snoring :Affecting 67.9% of the general population. Evaluation indexes

Apnea- hypopnea index AHI :(a). 5–15/ hr = mild, (b).15–30/ hr = moderate,(c). > 30/ hr = severe

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Problems and Rationale Physiology

HypertensionAtherosclerosis Coronary artery diseaseCognitive impairmentsSudden death during

sleep

PsychosisTiredSleepinessInattentionGrumpyDejection

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Problems and RationaleTechnology for sleep measurement

PSGActigraphyOximeter

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Source: Labsystem Source: myhealthyfeelingSource: Philips

Problems and RationaleThe global homecare respiratory market had

generated 15% compound annual growth from the year of 2009 to 2015.

112/04/208Source: 工研院 IEK (2009)

Purpose and Specific AimsTo develop analysis system for sleep

respiratory activitiesTo develop the analysis algorithm for sleep

respiratory activitiesTo establish database management system

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Background and Literatures ReviewRelative Thresholding With Under-Mattress

Pressure Sensors to Detect Central Apnea

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Daphne Townsend, Student Member, IEEE, Megan Holtzman, Student Member, IEEE, Rafik Goubran, Senior Member, IEEE, Monique Frize, Senior Member, IEEE, and Frank KnoefelIEEE TRANSACTIONS ON INSTRUMENTATION AND MEASUREMENT, VOL. 60, NO. 10, OCTOBER 2011

Background and Literatures ReviewMoving variance

Parameter selection framework

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Background and Literatures Review

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Background and Literatures ReviewValidation of Unobtrusive Pressure Sensor

Array for Central Sleep Apnea Screening

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Daphne Townsend, Student Member, IEEE, Rafik Goubran, Fellow, IEEE, Frank Knoefel, and Judith LeechIEEE TRANSACTIONS ON INSTRUMENTATION AND MEASUREMENT, VOL. 61, NO. 7, JULY 2012

Background and Literatures ReviewANTHROPOMETRIC INFORMATION FOR

STUDY PARTICIPANTS

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Background and Literatures ReviewBlock diagram of prevalidation work

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Background and Literatures Review

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Materials and MethodsSystem Architecture

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Pressure signals

Extraction ofParameters

Posture

Position

Movement

Resipiratory event

Recognition ofAbnormaibehavior

Bedridden behavior analysis

Bady Movement Databass

Recognition ofSleep Apnea

Pressure signal

Database

Sleep Apnea

Database

Materials and MethodsEvent tagging

PSG dataPressure sensing data

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Materials and MethodsSignal processing(49 channel)

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Materials and MethodsSignal proccessing(Matlab)

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Materials and MethodsTagging Resipiratory event (PSG)

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Materials and MethodsResipiratory event report

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Materials and MethodsDatabase(MSSQL)

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Database

Pressure Signal&

DateTime

Body Movement

MedicalInformation

DeviceImformation

Apnea Type

Materials and MethodsDatabase(MSSQL)

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Pressure Signal

Body Movement

MedicalInformation

DeviceImformation

Apnea Type

Preliminary ResultsBasic data of 40 subjects

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No. OSA CA Mix apnea Hypopnea Total1 6 0 0 60 662 0 0 0 56 563 113 1 1 172 2874 138 1 0 110 2495 43 6 3 179 2316 0 0 0 112 1127 18 0 0 110 1288 259 1 1 154 4159 87 1 0 30 118

10 187 0 30 146 36311 184 0 0 104 28812 102 5 6 78 19113 23 12 1 153 18914 338 0 1 74 41315 0 0 0 0 016 320 19 23 85 44717 409 0 0 30 43918 8 2 5 41 5619 38 0 0 102 14020 10 9 0 39 58

Preliminary Results

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21 172 0 0 8 18022 89 27 30 83 22923 16 0 0 196 21224 79 3 2 229 31325 33 0 0 41 7426 22 0 0 33 5527 145 17 70 223 45528 441 1 6 70 51829 179 3 4 63 24930 2 0 0 70 7231 29 6 0 25 6032 0 0 0 110 11033 8 0 0 59 6734 0 0 0 13 1335 76 4 0 45 12536 0 0 0 43 4337 69 7 2 54 13238 62 2 6 392 46239 79 1 2 98 180

Total 3784 128 193 3690 7795N=23 N=20 N=17 N=38 N=38

Preliminary ResultsRight lying Central sleep apnea(Pressure sensing

signal vs PSG)

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Future WorkEstablishment of analysis algorithm

Signal fusionFeature extraction

Database management systemCreate table

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ReferencesReferences[1]張慈映， 2009. 睡眠呼吸治療市場商機。工業技術研究院產業經濟與趨勢研究中心

[2]2013. 國人睡眠大調查。台灣睡眠醫學學會[3] R. Bhattacharjee, L. Kheirandish-Gozal, G. Pillar, and D. Gozal,

“Cardiovascular complications of obstructive sleep apnea syndrome: Evidence from children,” Prog. Cardiovasc. Dis., vol. 51, no. 5, pp. 416–433, 2009.

[4] W. Flemons andW. Tsai, “Quality of life consequences of sleep-disordered

breathing,” J. Allergy Clin. Immunol., vol. 99, no. 2, pp. S750–S756, 1997.

[5] W.W. Flemons,M.R.Littner, J.A.Rowley, P. Gay,W. M. Anderson, D.W.

Hudgel, R. D. McEvoy, and D. I. Loube, “Home diagnosis of sleep apnea:

A systematic review of the literature,” Chest, vol. 124, pp. 1543–1579,

2003.

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Thanks for your attention !Thanks for your attention !