SAD BOD Non-BOD0%

20%

40%

60%

80%

100%

2012 16

155

922

139

4616 18

≥3 2

1 0

SAD BOD Non-BOD0%

20%

40%

60%

80%

100%

58

33 37

14

4 5

319 10

≥2 1

0

Fazeka score

CMB number

Among 3 groups p=0.505

Among 3 groups p=0.288

(A) Leukoaraiosis (B) CMB

Figure e-1. Markers of microangiopathyThe degrees of leukoaraiosis (A) and number of cerebral microbleeds (B) in SAD vs. BOD vs. non-BOD.

p=0.499 p=0.203p=0.532 p>0.999