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嘉嘉嘉嘉 Introduction of speakers Tangchun Wu Huazhong University of Science and Technology, China Dr. Tangchun Wu is tenured Professor of Occupational and Environmental Health, the Dean of School of Public Health, vice-dean of Tongji Medical College, Huazhong University of Science & Technology (HUST), and National Outstanding Young Investigator, the Yangzi Scholarship and Principal Investigator (PI) of a 973 Program (the National Key Basic Research and Development Program). He graduated with a major in Preventive Medicine in 1988 and received his PhD in 1993 from Tongji Medical College. Dr. Wu’s research is mainly focused on effects of air pollution and interaction between environment and genes on cytokines, immune responses, genetic, epigenetic and environment-related diseases (especially coronary heart disease and lung cancer) and the corresponding mechanisms. Currently he is leading a 973 Project to investigate health hazards caused by ambient particulate matter and serves as PI of the Dongfeng-Tongji Cohort Study (DFTJ cohort) in Dongfeng Motor Corporation (DMC). He has published over 400 original papers (250 of them published in SCI-collected journals including JAMA, J Clin Oncol, Circulation, Environ Health Perspect, PLoS Med, GUT and Nature Genetics). Dr. Wu has served as Chair, co-Chair for many times, or keynote speaker at International Conferences on Occupational and Environmental Health, and Cell Stress. Dr. Wu is the recipient of the National Second Awards of both Natural Science and Scientific Advancement. Zhibin Wang Johns Hopkins University, USA Used to be a plant molecular biologist, Dr. Zhibin Wang started his biomedical and epigenomic training by developing ChIP-seq method for epigenomic mechanisms in regulation of gene expression and cell differentiation. After joining Johns Hopkins, his group has focused on the epigenomic changes in response to environmental 1 / 19

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嘉宾简介 Introduction of speakers

Tangchun Wu

Huazhong University of Science and Technology, China

Dr. Tangchun Wu is tenured Professor of Occupational and Environmental Health, the Dean of School of Public Health, vice-dean of Tongji Medical College, Huazhong University of Science & Technology (HUST), and National Outstanding Young Investigator, the Yangzi Scholarship and Principal Investigator (PI) of a 973 Program (the National Key Basic

Research and Development Program). He graduated with a major in Preventive Medicine in 1988 and received his PhD in 1993 from Tongji Medical College. Dr. Wu’s research is mainly focused on effects of air pollution and interaction between environment and genes on cytokines, immune responses, genetic, epigenetic and environment-related diseases (especially coronary heart disease and lung cancer) and the corresponding mechanisms. Currently he is leading a 973 Project to investigate health hazards caused by ambient particulate matter and serves as PI of the Dongfeng-Tongji Cohort Study (DFTJ cohort) in Dongfeng Motor Corporation (DMC). He has published over 400 original papers (250 of them published in SCI-collected journals including JAMA, J Clin Oncol, Circulation, Environ Health Perspect, PLoS Med, GUT and Nature Genetics). Dr. Wu has served as Chair, co-Chair for many times, or keynote speaker at International Conferences on Occupational and Environmental Health, and Cell Stress. Dr. Wu is the recipient of the National Second Awards of both Natural Science and Scientific Advancement.

Zhibin Wang

Johns Hopkins University, USA

Used to be a plant molecular biologist, Dr. Zhibin Wang started his biomedical and epigenomic training by developing ChIP-seq method for epigenomic mechanisms in regulation of gene expression and cell differentiation. After joining Johns Hopkins, his group has focused on the epigenomic changes in response to environmental perturbation in the

contribution to disease risk. As PIs or co-investigators on several University-, NIH-, and Foundation-funded grants, he laid the groundwork for the proposed research by developing novel approaches/algorithms with colleagues—ChIP-seq (Cell 2007; 5611 citations), ACE-mapping (Genome Biol. 2015, 45 citations), and MethylMosaic and NORED (Cell Discov. 2017)—to reveal the mechanisms of the maintenance/establishment of epigenetic codes. Ground-breaking discoveries include the first glimpse of “histone codes” in the human genome (Nature Genet. 2008,1837 citations) and the first report of HDACs binding to active but not silent genes (Cell 2009; 974 citations). His group recently first proposed a novel concept of regional “autosomal chromosome inactivation” for disease (Cell Discov. 2017). Current investigations in the lab have revealed intermediate factors bridging exposure and susceptible epigenomic loci for altering gene expression for disease risks.

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Xiangdong Li

Hong Kong Polytechnic University, Hongkong, China

Professor Xiang-dong Li is the Director of Research Institute of Sustainable Urban development, Chair Professor of Environmental Science and Technology at Department of Civil & Environmental Engineering, Associate Dean (Research) of Faculty of Construction and Environment, The Hong Kong Polytechnic University. He obtained his BSc in Earth Sciences and his MSc in Geochemistry from Nanjing University, and his PhD in Environmental Technology from Imperial College London.

Prof. Li’s major research interests include regional pollution, urban environmental studies, and remediation of contaminated soils. He has published more than 200 papers in leading international journals, and is one of the highly cited researchers in Environment/Ecology of the Web of Science database. He was awarded the Outstanding Young Researcher (Oversea) Fund from the Natural Science Foundation of China (NSFC) in 2007. Professor Li is the past president (2011-2013) of the International Society of Environmental Geochemistry and Health (SEGH). He is currently an Associate Editor for Environmental Science and Technology (ES&T). Prof. Li is also an associate editor and editorial board member for several other international journals in related research fields.

Antoine Snijders

Lawrence Berkeley National Laboratory, USA

Dr. Snijders received his Ph.D. (cum laude) in 2004 from the University of Utrecht, The Netherlands, in Cancer and Molecular Biology. He joined the Cancer Research Institute at the University of California San Francisco, as a postdoctoral scholar in 2005 after which he moved to the Lawrence Berkeley National Laboratory. Dr. Snijders’s research goals are to understand cancer tumorigenesis specifically addressing key questions concerning the

contribution of host genetics, environmental exposures and their interactions in cancer risk and tumor progression. His laboratory uses a systems biology approach, together with novel mouse models to identify genetic networks controlling susceptibility to cancer risk. The broad and long-term goals of his laboratory are to identify how the interactions of combinations of genes and their functional polymorphisms and environmental exposures contribute to disease susceptibility of individual human subjects. His lab exploits the power of mouse genetics using Collaborative Cross (CC) mice, together with OMICS analyses to determine the influence of individual variations in disease susceptibility. This comprehensive systems biology approach will likely identify specific genes or pathways that are differentially controlled between mouse strains, and contribute to human variation in susceptibility to environment factor-induced carcinogenesis.Dr. Snijders is currently the Chair of the LBNL Animal Welfare and Research Committee, the Chair of the LBNL Human Subjects Committee and the Chair of the BioEngineering and BioMedical Science Department. He is also the co-director of the LBNL Gnotobiotic Rodent Center. He is the inventor of 8 patents and has authored 5 book chapters.

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Bikha Ram Devrajani

Liaquat University of Medical & Health Sciences, Pakistan

Bikha Ram DEVRAJANI has earned his Bachelor of Medicine, Bachelor of Surgery in 1886 from Liaquat Medical College, Jamshoro-Hyderabad, University of Sindh. He got his Fellowship of College of Physicians and Surgeon’s of Pakistan in 1998 in Internal Medicine. In recognition of his services in academics and patients he was awarded Fellowship of American College of Physicians in 2012 and Fellowship of Royal College of Physicians

London in 2014. He is currently serving as Vice Chancellor of the University.Prof. DEVRAJANI’s research interest is mainly focuses on Endocrinology and Diabetes. Given his interest in Endocrinology and diabetes he established Sindh Institute of Diabetes and Endocrinology. Prof. DEVRAJANI is principal investigator and lead of many key projects including, Randomized controlled trial of rifaximin versus lactulose in the treatment of acute hepatic encephalopathy and Ankle brachial index (ABI) in patients with type 2 diabetes mellitus. In addition, his group has investigated Trace Metals Concentration in Patients with Oral Cancer by Atomic Absorption Spectroscopy and Is the deficiency of vitamin B12 related to oxidative stress and neurotoxicity in Parkinson's patients? He has published more than 115 papers in national and international peer-reviewed journals. He is also members of editorial board of a number of Journals.

Dianjun Sun

Center for Endemic Disease Control, Chinese Center for Disease Control and Prevention, China

Dianjun SUN, Director of Center for Endemic Disease Control, Chinese Center for Disease Control and Prevention, Vice President of Harbin Medical University. Prof. Sun is currently member of the Panel on the Subject of Preventive Medicine, Degree Committee of the State Council, chairman of

Endemic Disease Branch of Chinese Medical Association, chairman of Expert Advisory Committee of National Endemic Disease Prevention and Control, vice president of the Chinese Side of the China-Russia Medical University Alliance, executive director of the European Association for Predictive, Preventive & Personalized Medicine, chief editor of Chinese Journal of Endemiology, associate editor of Fluoride journal.Prof. SUN’s main research interests are the prevention, treatment and etiology of endemic diseases. He has organized many national key endemic disease control projects, such as the national screening for high fluorine and high arsenic water sources, the improvement of furnaces and stoves in the areas of fluorosis and arsenism caused by coal-burning pollution nationwide. Prof. Sun has made outstanding contributions to the control and elimination of key endemic diseases in China. Prof. SUN presided 8 projects of National Natural Science Foundation of China (including 1 key project), 2 projects of international cooperation and 1strategic consulting project of Chinese Academy of Engineering. He published 10 books as chief editor and published more than 300 papers.

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Herbert Yu

University of Hawaii Cancer Center, USA

Dr. Yu is a molecular epidemiologist, and his research focuses on cancer etiology and tumor biomarkers. Being trained in medicine, epidemiology and laboratory research, Dr. Yu conducts laboratory-based clinical and epidemiologic studies. He has designed and accomplished many clinical studies which assess the molecular and genetic features of tumor specimens in relation to disease characteristics and survival outcomes of patients with

breast, ovarian, prostate or lung cancer. He has also developed and participated in population-based epidemiologic studies to investigate gene-environment interactions in breast, endometrial, liver and pancreatic cancers. Dr. Yu has knowledge and experience in a wide range of research methodologies and laboratory technologies. Currently, using online high-throughput datasets, omics-technologies, molecular biology experiments, and in silico prediction of bioinformatics, he and his research team characterize the function and regulation of non-coding RNAs, and elucidate their roles in cancer. In collaboration with investigators from several research institutions, he recently completed an epidemiological study on liver cancer.

Guangwen Cao

Naval Military Medical University, China

Prof. Guangwen Cao is the chairman of the Department of Epidemiology, Second Military Medical University (Shanghai, China), The editor-in-chief, Hepatoma Research, vice-chairmen of Cancer Epidemiology Committee, Chinese Anti-Cancer Association. Prof. Cao serves as the principal scientist of the National Key Basic Research Program (973 program) in cancer research and the National Outstanding Young Scholar supported by National Scientific Foundation of China. He was graduated from Second

Military Medical University as PhD in Cancer Genetics in 1995, and MD degree in Clinical Medicine in 1989. During March 1999-Oct 2002, Dr. Cao received post-doc trainings at Baylor College of Medicine and University of Texas MD Anderson Cancer Center (Houston, TX). The major research interests of Prof. Cao are cancer revolution & development, HBV-induced hepatocarcinogenesis, colorectal carcinoma, gastric cancer, renal cell carcinoma, and molecular epidemiology of emerging infectious diseases. Based his own research experience on cancer biology and epidemiological researches, Prof. Cao also develop a novel theory for specific prophylaxis and control of malignancies - Cancer Evo-Dev. Prof. Cao ever served as team leaders in investigating outbreaks of emerging infectious diseases including SARS, dengue, adult scarlet fever, and novel Bunyamwera virus-induced idiopathic thrombocytopenic purpura. As corresponding authors, Prof. Cao published 140 research papers in international journals including J Clin Oncol, J Natl Cancer Inst, Gut, Hepatology, Ann Oncol, Am J Gastroenterol, and Clin Cancer Res. Prof. Cao serves as the Editor-in-Chief of an international scientific journal Hepatoma Research. Prof. Cao also serves as the Editor-in-Chief of several books including “Cancer Evo-Dev”, “Naval Epidemiology”, “Cancer Biotherapy”, and “Disaster Medicine”, etc.

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Zhiwei Sun

Capital Medical University, China

Zhiwei Sun, Professor, is the first-level academic leader and the director of Beijing Key Laboratory of Environmental Toxicology. He has been engaged in environmental epidemiology research which related to the toxicology of atmospheric particles, nanotoxicology, health effects and mechanism of air pollution. As the project leader, he has undertaken the national projects, provincial and ministerial projects, and the international cooperation

programs more than 20 items, including the National Key Research and Development Program, China-British Major Joint Research Program and the State Key Program of National Natural Science Foundation of China. He has published 307 academic papers, among them, 150 SCI papers have been published in Autophagy, EHP, EI, PFT, Nanotoxicology, Biomaterials and other academic journals, and compiled more than 10 textbooks and monographs as chief editor and deputy chief editor. He has won many honorary titles such as the State Council Special Allowance, the Outstanding Mid-Aged Expert of the Ministry of Health, the committee member of the Ministry of Education Institution of higher learning Teaching Guidance Committee of Public Health, the Key Teacher of the Ministry of Education, the Baogang Prominent Teacher, the leader of Beijing’s Talent and Innovation Team, et al. He is also the Chairman of Chinese Professional Committee on Hygiene Toxicology of Preventive Medicine and the Professional Committee on Respiratory Toxicology of Chinese Society of Toxicology.

Guanghui Dong

Sun Yat-Sen University, China

Dr. Dong is a Professor of environmental epidemiology and environmental toxicology. He has years of experience working as an environmental epidemiologist in China and his research areas of focus include adults and child health, environmental health, exposure assessment, indoor and outdoor air pollution. Also, His research area focused on the toxicological evaluation

of some components in PM10 and PM2.5, such as some persistent organic pollutant (PFOS, PBDEs) in ambient air particles. So far, Dr. Dong has published more than 100 papers in the international journals including Lancet Planetary Health, JAMA Network Open, EHP, etc. journals as first and corresponding author.

Zhengdong Zhang

Nanjing Medical University, China

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Distinguished Professor, is the Director of Science and Technology Department in Nanjing Medical University and the Director of the Key Laboratory of Modern Toxicology, Ministry of Education. He has been engaged in environmental genomic research related to cancers. He has undertaken the national projects more than 10 items and published more than 110 selected peer review papers. He has won the Second Prize of Natural Science of the Ministry of Education twice and the Third Prize of China Medical Science and Technology Award twice. He has also won many honorary titles such as the young and middle-aged expert with outstanding contributions in Jiangsu Province, the leader of outstanding scientific and technological innovation teams in Jiangsu Province, and the second-level training target of “333” in Jiangsu Province.

Jianmin Chen

Fudan University, China

Professor Jianmin Chen is the Director of the Shanghai Key Laboratory of Atmospheric Particle Pollution and Prevention (LAP3), Department of Environmental Science and Engineering, Fudan University, and the Associate Dean of Atmospheric Sciences in the same University. He received his PhD on Physical Chemistry in Fudan University in July 1993.Dr. Chen’s major interests focus on laboratory study and field

measurement of aerosol multiphase chemistry, reginal air pollution and haze formation. In his group, a series of advanced instruments has been recently built up such as aerosol chamber, monitoring instrument for aerosols and gases analyzers (MARGA, URG), wide-range particle spectrometer, Tof-ACSM, TDMA, Laser-CRDS, et al., to investigate aerosols’ size distribution, hygroscopicity, optical property and chemical composition. He is PIs of 23 projects founded by NSFC, MOST and H2020, et al. He has published over 290 papers in leading international journals, 34 Chinese patents. He received honors and awards including the 1st Rank Award of Natural Sciences by the Ministry of Education, Chevalier dans L'ordre des Palmes Cadémiques. Dr. Chen is currently an Associate Editor for Science of the Total Environment, Associate Editor for Heliyon Environment. He is also the editorial board member for several other international journals in related fields.

Weimin Gao

West Virginia University, USA

Weimin Gao is currently Professor and Chair in the Department of Occupational and Environmental Health Sciences, School of Public Health, West Virginia University. Dr. Gao received Bachelor of Medicine in Preventive Medicine from the Nanjing Medical University in 1994 and subsequently MPH in Occupational Medicine & Toxicology from the Chinese Academy of Preventive Medicine in 1997. He further received his

MS degree in Biostatistics and PhD in Environmental and Occupational Health from the Graduate School of Public Health of the University of Pittsburgh in 2003. He was a Research Fellow in the Department of Internal Medicine at School of Medicine, University of Michigan from 2003 to 2004.

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Dr. Gao has been working as an Assistant/Associate/Full Professor in the Department of Environmental Toxicology and the Institute of Environmental and Human Health at Texas Tech University and Texas Tech Health Sciences Center in 2006-2018. His current research focuses on the areas of occupational and environmental health, molecular toxicology, carcinogenesis, cancer targeted therapy, cancer chemoprevention, and molecular epidemiology. He received funds from federal agencies including NIH. He has supervised many research scientists and graduate/undergraduate students. He has published over 90 peer-reviewed articles and served as a reviewer for various internationally recognized journals in his research field. He was selected by Society of Toxicology as the Host for 2016 Global Senior Scholar Exchange Program.

Qingshun Zhao

Model Animal Research Center of Nanjing University, China

Qingshun Zhao obtained his B.S. degree in 1987 and M.S. degree in 1990 from Nanjing University (Nanjing, Jiangsu, China), and received his Ph.D. degree in 2001 from Purdue University (West Lafayette, Indiana, USA). From 2001 to 2003, Qingshun did his postdoctoral research in Duke University Medical Center (Durham, North Carolina, USA). In 2003, he

became an associate professor and a principal investigator in Model Animal Research Center, Nanjing University. In 2006, Qingshun was promoted full professor of Nanjing University. The research interests of the Zhao Lab focus on developmental biology and developmental toxicology of Zebrafish.

Shixiang Gao

Nanjing University, China

Dr. Shixiang GAO is a professor in School of the Environment, Nanjing University. He obtained his Ph.D. from Nanjing University in 1999. His research is focused on the environmental behavior, eco-toxicology, and health risk assessment of organic contaminants. Currently his study is particularly involved in the bioaccumulation and transformation of certain persistent and/or emerging pollutants (halogenated and

phosphorous flame retardants, pharmaceuticals, and hormones) in water and organisms and their effects on human health. Dr. Gao has published more than 100 research papers in peer reviewed journals,

including ES&T, Water Research, etc. with more than 2600 citations.

Hailin Wang

Research Center of Eco-Environmental Sciences, Chinese Academy of Sciences, China

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Dr. Hailin Wang obtained his PhD at the Dalian Institute of Chemical Physics, Chinese Academy of Science, in 1997, and had done research as a postdoctoral fellow and research associate (2000-2005) at the University of Alberta, Canada. He has his expertise in epigenetics, in particular, DNA methylation and demethylation, a pioneer for the discovery of DNA N6-methyladenine in high eukaryotes. He also has his expertise in ultrasensitive analytical technologies (e.g., capillary electrophoresis-laser induced fluorescence polarization, single molecule fluorescence imaging, and UHPLC-MS/MS) for detection of carcinogenic DNA adducts and for study of DNA-repair proteins interactions. He published 100 peer-reviewed papers on leading journals, including Cell, Nature, Cell Stem Cell, Mol Cell, Hepatology, Cell Res, Proc. Natl. Acad. Sci. USA, J. Am. Chem. Soc., Cell Discovery, Nucleic Acids Research, Analytical Chemistry. He won a number of wards, “Presidential Special Award for Graduate Student” by the Chinese Academy of Sciences (1997), “CAIA” Scientific Award, first medal (2010, 2013), “Excellent Nominee” for “Hundreds of Talents” plan by the Chinese Academy of Sciences (2011), “CAIA” Scientific Award, Special medal (2015), Outstanding Science and Technology Achievement Prize of the Chinese Academy of Sciences (2013), “Outstanding Young Scientists” by the National Science Foundation of China (2011), Excellent for “Outstanding Young Scientists” by the National Science Foundation of China (2016).

Lihua Zhang

Dalian Institute of Chemical Physics, Chinese Academy of Sciences, China

Prof. Dr. Lihua Zhang obtained her Bachelor degree of Science from Jilin University in 1995, and obtained her Ph.D. degree from Dalian Institute of Chemical Physics (DICP), Chinese Academy of Sciences (CAS) in 2000. From 2001 to 2003, she carried out the postdoctoral research in Japan. In April 2003, she went back to work in DICP, CAS, and promoted to be a full

professor in 2005. Now she is the group leader of “High efficient separation and characterization of biomolecules group”. Her research interest is focused on the development of new methods for proteome qualitation, quantitation and interaction. She published more than 200 SCI papers, won the second Prize for National Natural Science Award in 2012, and obtained the funding for outstanding young scientist from National Natural Science Committee in 2017.

Quazi Quanruzaman

Dhaka Community Hospital Trust, Bangladesh

Quamruzzaman QUAZI is locally recognized as freedom fighter duringBangladesh Genocide 1971.He graduated from Chittagong Medical College, Bangladesh then he moved on to study general surgery in Royal College of Physicians and Surgeons, Glasgow, UK and also Royal College of Surgeons, Edinburgh, UK and completed his study in Pediatric Surgery from International College of Surgeons, USA. He then founded Dhaka

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Community Hospital (DCH) in 1988 in an effort to bring affordable, high-quality tertiary health care to the underprivileged community throughout Bangladesh. In addition to providing health care, DCH brought the issue of environmental arsenic exposure to the world wide attention by detecting the seriousness health problems caused by epidemic arsenic contamination in the groundwater of Bangladesh.Prof. QUAZI is a member of National Health Policy Committee, Gov. of Bangladesh,1996-2001, Member of National Steering Committee for Arsenic, Gov. of Bangladesh, 2004-till date, Co-Founder of Gonoshastha Kendro, Chairman of Bangladesh Disaster Preparedness Center (BDPC), and founder of the Association of Paediatric Surgeons of Bangladesh (APSB). Ministry of Health, Bangladesh Government was Awarded Prof. Quazi Quamruzzaman Best Pediatric Surgeon Award-2016. The Award name after Prof. Quazi Quamruzzaman.

How-Ran Guo

National Cheng Kung University, Taiwan, China

How-Ran GUO earned his medical degree in 1988 from the Taipei Medical College (currently Taipei Medical University). Then he earned a Master of Public Health in 1989, a Master of Science in Epidemiology in 1990, and a Doctor of Science in Environmental Health in 1994, all from the School of Public Health, Harvard University in the U.S. He had served as an

Epidemic Intelligence Service Officer at the Centers for Disease Control and Prevention and a faculty member at the University of Cincinnati before going back to Taiwan in 1996. Prof. GUO has a broad research interest covering various topics in environmental and occupational health. He is now a Director of the Workers’ Health Service Center in the Southern Region and also in charge of coordinating all the centers in Taiwan. He is the Principal Investigator of one project each funded by the Ministry of Science and Technology (MOST) and Environmental Protection Administration on the health effects of fine particulate matters. He has published more than 300 papers in international peer-reviewed journals.Prof. GUO is currently the Directors of Occupational Safety, Health, and Medicine Research Center and the Chair of Department of Occupational and Environmental Medicine of the National Cheng Kung University (NCKU). He is also an Attending Staff at the NCKU Hospital. In 2018, he received the Award for Contributions to Occupational Safety and Health from the Ministry of Labor.

Aihua Zhang

Guizhou Medical University, China

Aihua ZHANG is the professor and the doctoral supervisor of Guizhou Medical University. She is also the provincial management experts and outstanding teacher of Guizhou province, and the expert enjoying the state council special allowance. She has serving as the director of the key laboratory of the ministry of education for environmental pollution monitoring and disease control, the director of Guizhou health development

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research institutes and the counselor of Guizhou provincial people's government. She has been engaged in the teaching and research work of public health and preventive medicine for 39 years. Her main research interests are focused on environmental toxicology and mechanism of endemic arsenism. Prof. ZHANG has presided over 9 national foundation projects, including the Key projects of the national natural science foundation, and more than 30 provincial and ministerial fund projects. She is also as the chief editor, deputy editor or co-editor in the compilation of 15 national planning textbooks and monographs. More than 300 research papers have been published in international and national journals. Successively won 8 provincial science and technology awards (6 items ranked no.1, 2 items ranked no.2). She is also as the member of the preventive medicine teaching advisory committee of the ministry of education, the member of the ehdemic disease standards committee, the council member of the Chinese society of toxicology et al. She also acts as the deputy editor-in-chief of the Chinese journal of local medicine.

Jingbo Pi

China Medical University, China

Jingbo PI received his Bachelor degree in Preventive Medicine in 1990 and M.S. on Occupational Health in 1995 from China Medical University, and Ph.D. in Medical Sciences from The University of Tsukuba, Japan in 2002. Prof. PI had postdoctoral training at NIEHS, USA (2002-2004) and The Hamner Institutes for Health Sciences, USA (2004-2006). He worked as a Research Investigator, Assistant Investigator and Associate Investigator at

The Hamner Institutes for Health Sciences (2006-2013). In 2013, Dr. Pi was recruited as a professor of China Medical University, and since then he has been serving as the Dean of School of Public Health, China Medical University. In 2008, Dr. Pi received the Outstanding New Environmental Scientist (ONES) Award, NIEHS, USA. Dr. Pi’s research focus is on environmental oxidative stress and chronic diseases, including cancer and metabolic disorders. He has authored/co-authored over 100 peer-reviewed papers with more than 5500 citations and with RG score and h-index of 40.58 and 40, respectively. Prof. Pi has served as a board member and president or vice president of Stem Cell Specialty Section, SOT, USA and multiple Specialty Sections of Chinese SOT. He currently is an Associate Editor of Toxicology and Applied Pharmacology and Toxicology Reports.

Binafsha Manzoor Syed

Liaquat University of Medical & Health Sciences, Pakistan

Binafsha Manzoor SYED has earned her Bachelor of Medicine, Bachelor of Surgery in 2002 from Liaquat University of Medical & Health Sciences, Jamshoro, Pakistan. She got her PhD in Breast Surgery/Clinical Sciences in 2012 from School of Clinical Sciences, The University of Nottingham, England. She is currently serving as the Director ORIC & MRC, and Head of Clinical Research Division, Medical Research Centre, Liaquat University of Medical & Health Sciences, Jamshoro, Pakistan.

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Prof. SYED’s research interest is mainly focuses on Cancer in particular therapeutic targets. She conducts regular workshops on research subjects. She is also Master trainer for PhD Supervisors training.Prof. SYED is principal investigator and lead in two key projects to study: 1) Molecular pattern of Breast cancer in Pakistani population and 2) Biological characterization of colorectal cancers in correlation with clinical parameters and outcome; funded by Higher Education Commission of Pakistan.Prof. SYED has published more than 21 papers in international peer-reviewed journals, she a many abstracts presented at International platforms. She is also author of a book chapter on HER2 positive breast cancer published by NOVA Publishers New York.

Qizhan Liu

Nanjing Medical University, China

Qizhan LIU earned his Bachelor degree in preventive medicine in 1986 from Hunan Medical College (HMC). He got Master degree in occupational medicine and environmental health in 1989 and Ph. D in toxicology in 2003 from Sun Yat-sen University (SYSU). He joined in toxicology of Nanjing Medical University (NMU) from 2004 to 2007 and in molecular & cellular pathology of University of Alabama at Birmingham

(UAB) from 2007 to 2009.Prof. LIU’s research interest is mainly focused on the mechanism and prevention of arsenic poisoning, the biochemical and molecular toxicology, and the mechanism of chemical carcinogenesis. He is the deputy of Society of Chinese Toxicology Association (CTA), the deputy of Chinese Environmental Mutagen Society (CEMS), the vice chairman of Biochemical and Molecular Toxicology Society of Chinese Toxicology Association (CTA), and the deputy of Endemiological Society of Chinese Medical Association (CMA).Prof. LIU is PI of 8 Natural Science Foundation of China (NSFC) grants to study the mechanisms and interventions of lung and liver damages, as well as carcinogenesis induced by arsenic exposure and smoking. He has published 100 papers in international peer-reviewed journals including Environ Health Perspect, Archives of Toxicology, Toxicology Science, etc. Prof. LIU as the first winner won 2 second prizes for scientific and technological achievements in Jiangsu Province and the Ministry of Education.

Xudong Liao

University Hospitals Cleveland Medical Center, USA

Xudong Liao earned his Bachelor of Science degree in physiology and biophysics from Peking University with honor in 1998, PhD in Biochemistry and Molecular Biology from Peking Union Medical College in 2003. He continued his postdoctoral training at Cleveland Clinic from 2004 to 2008 before joining Case Western Reserve University School of

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Medicine. Currently, Dr. Liao is an assistant professor at Case Cardiovascular Research Institute and University Hospitals Cleveland Medical Center. Dr. Liao’s research mainly focuses on cardiovascular diseases with particular interest in the interaction between innate immunity and cardiovascular system. He is the principle investigator of multiple AHA grants. His work has been well recognized by the peers, with publications in high profile journals including JCI and PNAS, and a combined citation count over 2000.

Yun Chen,

Nanjing Medical University, China

Dr. Chen obtained her B.S. and M.S. at Nanjing University, China. In 2006, she got her Ph.D. in University of Minnesota, USA and then worked in Charles River Laboratory, USA for two years. After that, she joined Nanjing Medical University, China and got a full professor position at School of Pharmacy.Currently, Dr. Chen's research interests include the development and

validation of liquid chromatographytandem mass spectrometry (LCMS/MS)based targeted proteomics assays for biomarker analysis and discovery; sample enrichment and pretreatment for low abundant biomarkers; and investigation of drug resistance mechanism. Her research is supported by The National Natural Science Fund (21722504, 21675089, 21175071), the SEU-NJMU cooperation project (2242017K3DN12), the Primary Research & Development Plan of Jiangsu Province (BE2018725) and the Open Foundation of State Key Laboratory of Reproductive Medicine [SKLRM-GA201804].

Ikram Din Ujjan

Liaquat University of Medical & Health Sciences, Pakistan

Ikram Din UJJAN has earned his Bachelor of Medicine, Bachelor of Surgery in 1997 from Liaquat Medical College, Jamshoro-Hyderabad, University of Sindh, Pakistan. He got his Ph.D in Haematology in 2015. He currently working as Professor of Pathology and Dean Basic Sciences. He is approved supervisor of Ph.D, FCPS, M.Phil Hematology and DCP at LUMHS and administrator of Diagnostic & Research lab of LUMHS Hyderabad. In

recognistion of his service in upgradation of the academic at Liaquat University he was awarded “excellence award in 2018 and best teacher award by Higher Education Commission of Pakistan. Prof. UJJAN’s research interest is mainly focused on Haematology. His ongoing research projects are Incidence of Ebstein virus in acute lymphoblastic leukemia in Sindh, Helicobacter Pylori and ITP and effect of eradication therapy on platelet count and Hemoglobinopathy pattern at Hyderabad Sind. In addition, his group has investigated Seroprevalence of HBsAg and anti-HCV in healthy blood donors and a comparative study of red cell folate and serum folate levels in patients on regular Hemodialysis. His recent research work focuses on Typhoid in Pakistan.Prof. UJJAN has published more than 50 papers in national and international peer-reviewed journals.

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Jianhua Mao

Lawrence Berkeley National Laboratory, USA

Jian-Hua Mao earned his Bachelor degree in applied mathematics in 1986 from Southeast University and Master degree in biostatistics and cancer epidemiology in 1989 from Beijing Medical University. He received his PhD degree in cancer genetics from the Department of Radiation Oncology, University of Glasgow, United Kingdom. He received the post-doctoral

training in the Department of Medical Oncology, University of Glasgow. Dr. Mao is a geneticist senior scientist in the Biological Systems and Engineering Division, Lawrence Berkeley National Laboratory and adjunct professor of Comparative Biochemistry Program, University of California Berkeley. His research interests include: (1) Identify the combinations of genes and their functional polymorphisms that affect the susceptibility to tumor development; (2) Discover genetic alterations in tumors using recently developed high throughput technologies, such as CGH microarray, SNP microarray, gene expression microarray, and next generation sequencing; (3) Study the functional and mechanistic role of new discovered genes in tumor development using genetic engineering mice; (4) Identify the biomarkers for early diagnosis, prognosis and response sensitivity to therapies; and (5) Investigate the roles of gut microbiome in disease development and treatment. Dr. Mao has received many research grants from NIH, DOE, NASA et al. He was the leader of Project 2 of the DOE funded Low‐Dose Radiation Research Project (2008-2016) focused on systems genetic analysis of the relative contribution of non‐targeted versus targeted radiation effects on cancer risk. He has authored more than 150 peer-reviewed publications including Nature, Science, Nat Genet, Cancer Cell, JCO, Cancer Res, etc.

Shouxiong Huang

University of Cincinnati, USA

Shouxiong HUANG earned his bachelor degree in basic Chinese Medicine from Beijing University of Chinese Medicine in 1993. He received a PhD degree in veterinary preventive medicine from the Ohio State University in 2003. He then continued with postdoctoral and instructor positions in immunology programs at Washington University School of Medicine and Brigham Women’s Hospital at Harvard Medical School. In 2013, he became

an assistant professor in the Department of Environmental Health at the University of Cincinnati College of Medicine. Dr. Huang’s research interests focus on T cell responses in tuberculosis and environmental exposure. He has discovered the requirement, endocytic pathway, and evolutionary conservation of antigen presentation for activating mucosal-associated invariant T cells. He has also established a lipidomic platform and comprehensively profiled human lipid molecules functioning as agonists or antagonists for T cell activation. Currently, he investigates the structures and function of mycobacterial metabolite antigens in immune defenses against Mycobacterium tuberculosis infection and lipid regulators in environmentally exacerbated inflammation. He has published multiple

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immunology and immunotoxicology articles in peer-reviewed journals including Nat Immunol, J Exp Med, PNAS, Sci Rep, and Front Immunol, etc.

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