HIV, AIDS, & Your HIV, AIDS, & Your Immune SystemImmune System

By Daniel MarxBy Daniel Marx

The Immune SystemThe Immune System To be “immune” means to be To be “immune” means to be

protected. protected. Your immune system is made up of Your immune system is made up of

cells, tissues, and organs that work cells, tissues, and organs that work together to protect your bodytogether to protect your body

Your body consists of white and red Your body consists of white and red blood cellsblood cells

White blood cells form the immune White blood cells form the immune systemsystem

2 Kinds of White Blood Cells2 Kinds of White Blood Cells 1) Phagocytes – Chew up 1) Phagocytes – Chew up

invading germsinvading germs 2) Lymphocytes (B cell) – 2) Lymphocytes (B cell) –

Remember and recognize Remember and recognize previous invaders (i.e. previous invaders (i.e. chicken pox)chicken pox)

It is a type of lymphocyte, It is a type of lymphocyte, or “helper T cell” that is or “helper T cell” that is involved in fighting off HIV involved in fighting off HIV

AntigenAntigen - Thing that, - Thing that, when introduced into the when introduced into the body, triggers the body, triggers the production of an antibody production of an antibody by the immune system, by the immune system, which will kill the antigen which will kill the antigen that is recognized as a that is recognized as a foreign invader. foreign invader.

Process of Immune SystemProcess of Immune System

What Is HIV?What Is HIV?

““HIV” stands for human HIV” stands for human immunodeficiency virusimmunodeficiency virus

It is a virus that attacks your immune It is a virus that attacks your immune system by latching onto Helper T cells system by latching onto Helper T cells

Uses T cells to reproduce, or “replicate”Uses T cells to reproduce, or “replicate” Eventually overwhelms the body and Eventually overwhelms the body and

becomes AIDSbecomes AIDS Or “autoimmune deficiency syndrome”Or “autoimmune deficiency syndrome”

HIV Skit!HIV Skit!

I will need 7 I will need 7 volunteers volunteers

Each will take a role:Each will take a role: • 1 Narrator • 1 Person • 2 Immune Defenses • 1 Disease • 1 HIV virus • 1 ARV pill

Instructions: The Person will just

stand there. The Immune Defenses will stand in front of the person, blocking the Disease until HIV pushes them aside. The ARV can come in and help the immune system push HIV back.

How Can You Get HIV??How Can You Get HIV??

HIV Incidence and Prevalence, US, HIV Incidence and Prevalence, US, 1977-20061977-2006

(Hall, Song, Rhodes, et al. 2008) (Hall, Song, Rhodes, et al. 2008)

Prevalence RatesPrevalence Rates

(Hall, Song, Rhodes, et al. 2008)(Hall, Song, Rhodes, et al. 2008)

Initial Signs of HIVInitial Signs of HIV

How Can We Prevent HIV?How Can We Prevent HIV?

Get Tested!Get Tested! Safe Sex (OR) AbstinenceSafe Sex (OR) Abstinence Avoid sharing needlesAvoid sharing needles Don’t Share razors or toothbrushesDon’t Share razors or toothbrushes

(Department of Health and Human Services)(Department of Health and Human Services)http://www.cdc.gov/hiv/resources/http://www.cdc.gov/hiv/resources/

brochures/livingbrochures/livingwithhiv.htm#q8withhiv.htm#q8

ReferencesReferences Center for Disease Control and Prevention (2011). HIV/AIDS. Retrieved from Center for Disease Control and Prevention (2011). HIV/AIDS. Retrieved from

http://www.cdc.gov/hiv/.http://www.cdc.gov/hiv/.

Hall HI, Song R, Rhodes P, et al. (2008). Estimation of HIV Incidence in the US. Hall HI, Song R, Rhodes P, et al. (2008). Estimation of HIV Incidence in the US. JAMA, JAMA, 300 300 520-529. 520-529.

Kim, S., Lagos, C., Lukomnik, J., Molacek, E., Murguia K. (2007). HIV/AIDS Educational Kim, S., Lagos, C., Lukomnik, J., Molacek, E., Murguia K. (2007). HIV/AIDS Educational Activities Lesson Plans. Beyond Traditional Borders Student Project. Retrieved from Activities Lesson Plans. Beyond Traditional Borders Student Project. Retrieved from http://http://www.btb.rice.edu/design.cfm?doc_idwww.btb.rice.edu/design.cfm?doc_id =12214=12214..

The Nemours Foundation. (1995-2011). KidsHealth: HIV & AIDS. Retrieved from The Nemours Foundation. (1995-2011). KidsHealth: HIV & AIDS. Retrieved from http://kidshealth.org/kid/health_problems/infection/hiv.htmlhttp://kidshealth.org/kid/health_problems/infection/hiv.html ..

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Kahn, J. O. and Walker, B. D. (1998). "Acute Human Immunodeficiency Virus type 1 Kahn, J. O. and Walker, B. D. (1998). "Acute Human Immunodeficiency Virus type 1 infection". infection". N. Engl. J. Med.N. Engl. J. Med. 331331 (1): 33–39. (1): 33–39. doidoi::10.1056/NEJM19980702339010710.1056/NEJM199807023390107 . . PMID 9647878. PMID 9647878.

Daar ES, Little S, Pitt J, Daar ES, Little S, Pitt J, et al.et al. (2001). "Diagnosis of primary HIV-1 infection. Los Angeles (2001). "Diagnosis of primary HIV-1 infection. Los Angeles County Primary HIV Infection Recruitment Network". County Primary HIV Infection Recruitment Network". Ann. Intern. Med.Ann. Intern. Med. 134134 (1): 25–9. (1): 25–9. PMID 11187417. PMID 11187417.