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Curriculum Vitae Iacob Maria Speranta
© Uniunea Europeană, 2002-2013 | http://europass.cedefop.europa.eu Pagina 1 / 18
INFORMAŢII
PERSONALE
IACOB MARIA SPERANTA
Adresa (spital): Centrul pentru Boli Digestive si Transplant Hepatic
Institutul Clinic Fundeni
Şoseaua Fundeni nr. 258
022328 Bucureşti, România
+4021 2750500(centrala);
Fax: +40213180447(secretariat);
Sexul F | Data naşterii 08/04/1977 | Naţionalitatea romana
EXPERIENŢA
PROFESIONALĂ
EDUCAŢIE ŞI
FORMARE
2002 Diploma de medic: 545/ 21.03.2002 Seria T Nr. 0028346 Romania
2002 Medic rezident gastroenterologie, Certificat 073/ 12.12.2002
2007 Medic specialist gastroenterologie: OMS 2140/2007
2013 Medic primar gastroenterologie: OMS 1044/2013
Etape medicale si
universitare
In prezent
Pozitia ocupata: Sef de lucrari, Medic primar gastroenterologie
Tipul sau sectorul de activitate: Asistenta medicala de specialitate,
gastroenterologie
2016 - prezent Sef de lucrari UMF Carol Davila
2013 -prezent Medic primar gastroenterologie - OMS 1044/2013
2007 - prezent Medic specialist gastroenterologie - OMS 2140/2007. Centrul pentru Boli
Digestive si Transplant Hepatic, Institutul Clinic Fundeni, Bucuresti.
2007 - 2010 Cercetator prin concurs validat de Academia de Stiinte Medicale cu adeverinta nr
496/2007. Centrul pentru Boli Digestive si Transplant Hepatic, Institutul Clinic
Fundeni, Bucuresti
2002-2006 Medic rezident gastroenterologie - Certificat 073/ 12.12.2002. Centrul pentru
Boli Digestive si Transplant Hepatic, Institutul Clinic Fundeni, Bucuresti.
2003-2007 Asistent de cercetare, prin concurs validat de Academia de Stiinte Medicale cu
adeverinta nr 91/2003. Centrul pentru Boli Digestive si Transplant Hepatic,
Institutul Clinic Fundeni, Bucuresti
Curriculum Vitae Iacob Maria Speranta
© Uniunea Europeană, 2002-2013 | http://europass.cedefop.europa.eu Pagina 2 / 18
1995-2001 Universitatea de Medicina si Farmacie „Carol Davila” Bucuresti
2002
Diploma de licenta Nr 545/21.03.2002, Titlul de Doctor - Medic, absolvent UMF
„Carol Davila Bucuresti”, Facultatea de Medicina.
2001-2002 Spitalul Universitar de Urgenta, Bucuresti : 1 stagiu clinic de Neonatologie si
Institutul Clinic Fundeni, Clinica de Pediatrie - 1 stagiu clinic de Pediatrie in
Cadrul Rezidentiatului de Pediatrie
2002-2007 Centrul de Gastroenterologie si Hepatologie Fundeni: medic rezident
gastroenterologie
2006-2010 Studii doctorale sub coordonarea Prof Dr. Irinel Popescu
2007-2010 Bursa de cercetare pentru Tinerii Doctoranzi acordata de Consiliul National de
Cercetare Stiintifica
2010 Doctor in Medicina. Ordin MECTS Nr 4387/06.06.2011. Titlul Tezei de Doctorat:
„Hepatita recurenta C posttransplant hepatic – strategii terapeutice si factori
asociati cu recurenta severa”
2011 Obtinerea Diplomei Europene in Medicina de Transplant – Modulele 1 (Trunchi
Comun) si 4 (Transplantul hepatic) prin examen sustinut la Glasgow pe 7
Septembrie 2011
Afiliere la societati si
publicatii profesionale
2001 - in prezent Membru al Societatii Romane de Gastroenterologie & Hepatologie (SRGH)
2001 – in prezent Membru al Societatii Romane de Endoscopie Digestiva
(SRED)
2002 – 2004 Membru al Socientatii Romane de Nutritie Enterala si Parenterala (ROSPEN)
2002 – 2004, 2018- in
prezent
Membru a ROMTRANSPLANT
2003 - 2008 Membru al Asociatiei Internationale a Chirurgilor si Gastroenterologilor (IASG)
2004 - 2008 Membru al American College of Gastroenterology (ACG)
2005 – in prezent Membru al European Association for the Study of the Liver (EASL)
2007- in prezent Membru al Clubului Roman de Boala Crohn si Colita Ulcerativa (RCCC)
2008 – in prezent Membru al Societatii Internationale de Transplant (TTS)
2008 – in prezent Membru al Societatii Europene de Transplant de Organe (ESOT)
2009 – in prezent Membru Fondator al “Women Leaders in Transplantation” (WLIT)
2010 - 2011 Membru al Societatii Europene de Crohn si Colita (European Crohn’s and
Colitis Organization) (ECCO)
2018 - in prezent Membru in Comitetul Editorial al „Surgery, Gastroenterology and Oncology”
- Official journal of the International Association of Surgeons,
Gastroenterologists and Oncologists
COMPETENΤE
PERSONALE Diploma Europeana in Medicina de Transplant – Modulele 1 (Trunchi
Comun) si 4 (Transplantul hepatic) - supraspecializarea Transplant Hepatic
Curriculum Vitae Iacob Maria Speranta
© Uniunea Europeană, 2002-2013 | http://europass.cedefop.europa.eu Pagina 3 / 18
Limba(i) maternă(e)
Romana
Alte limbi străine cunoscute ΙNΤELEGERE VORBIRE SCRIERE
Ascultare Citire Participare la
conversaţie Discurs oral
Engleza C2 C2 C2 C2 C2
Franceza B2 B2 B2 B2 B2
Germana A2 A2 A2 A2 A2
Scrieţi denumirea certificatului. Scrieţi nivelul, dacă îl cunoaşteţi. Niveluri: A1/2: Utilizator elementar - B1/2: Utilizator independent - C1/2: Utilizator experimentat
Cadrul european comun de referinţă pentru limbi străine
Competenţe de comunicare Bune competenţe de comunicare dobândite prin experienţa in cadrul activitatii
clinice si de cercetare de peste 14 ani, participant cu lucrari de specialitate la
numeroase manifestari stiintifice internationale si nationale
Autor de lucrari publicate in reviste cu peer review si recenzori internationali
Functii administrative
si de conducere
2012 – 2019
2018 – prezent
2019 – 2023
Reprezentant National in Bordul European de Medicina de Transplant
Secretar al RoALD (Romanian Association for Liver Diseases)
Secretar Senior al Bordului European de Medicina de Transplant
2014 - prezent Responsabil cu gestionarea datelor din Registrul National de Transplant in cadrul
Institutului Clinic Fundeni Bucuresti – Centrul pentru Boli Digestive si Transplant
Hepatic conform Ordinului ministrului Sanatatii 983/26 August 2014
Competente dobandite la
locul de munca
Endoscopie digestiva diagnostica (abilitate inclusa in standardul profesional).
Ultrasonografie generala (abilitate inclusa in standardul profesional).
Competente informatice Utilizator experimentat PC (MS Office, Windows).
Pregătire
postuniversitară
(CURSURI ŞI
SPECIALIZĂRI)
1 Noiembrie 2000 Curs Precongres: Simpozionul National de Gastroenterologie, Hepatologie si
Endoscopie Digestiva, Bucuresti, 2000
Aprilie 2001 EASL Post-Graduate Course: Clinical Management of Portal Hypertension and Its
Complications, 36-th EASL Meeting, Prague, CZECH REPUBLIC
Curriculum Vitae Iacob Maria Speranta
© Uniunea Europeană, 2002-2013 | http://europass.cedefop.europa.eu Pagina 4 / 18
Martie 2002 POSTGRADUATE COURSE IN HEPATO-GASTROENTEROLOGY organized
by The National French Society of Gastroenterology, Nantes, FRANCE
Aprilie 2002 Stagiu practic 2 saptamani in Clinica de Gastroenterologie a Spitalului “EDOUARD
HERRIOT”, LYON, FRANCE
6-7 Decembrie 2002 Simpozionul “Afectiuni peptice digestive la inceputul mileniului III – optiuni
diagnostic, solutii terapeutice”, Campina, Romania
18 Februarie 2003 Simpozionul “Noua generatie de terapie antivirala in hepatita cronica C”, Hotel
Crowne Plaza, Bucuresti
17-18 Martie 2003 Tehnica de montare endoscopica a gastrostomei percutane, Institutul Clinic Fundeni,
Bucuresti
9-11 Aprilie 2003 Al cincilea simpozion si curs postuniversitar al IASG “Actualitati in bolile ficatului”,
Bucuresti, Romania
24 Septembrie 2003 PRECONGRESS COURSE “Actualities in gastroenterology and hepatology”, 9-th
Congress of Gastroenterology, Hepatology and Gastrointestinal Endoscopy, Craiova,
Romania
3 Octombrie 2003 SIMPOZIONUL “ROLUL LIMFOCITELOR T IN IMUNOPATOGENEZA
HEPATITELOR CRONICE”, INSTITUTUL CLINIC FUNDENI, BUCURESTI
Octombrie 2003 ADVANCED POSTGRADUATE COURSE IN GASTROENTEROLOGY
organized by The Holland Digestive Disease Week Foundation, The Netherlands
19-23 Octombrie
2003
10 th CLINICAL COURSE OF EUROPEAN SOCIETY FOR CLINICAL
NUTRITION AND METABOLISM, Izvorani, Romania
Decembrie 2003 EASL School of Hepatology Course 1 – Chronic Liver Diseases
Geneva, Switzerland
12 Martie 2004 European Postgraduate Gastro-surgical School, 4th
Amsterdam International Update
on Hepatology: Hepatitis B and C and Hepatocellular Carcinoma, Academic Medical
Center, Amsterdam, The Netherlands
3-4 aprilie 2004 POSTGRADUATE COURSE IN HEPATO-GASTROENTEROLOGY organized
by The National French Society of Gastroenterology, Paris, FRANCE
Iunie 2004 EASL School of Hepatology Course 2 – Complications of cirrhosis and liver cancer,
Barcelona, SPAIN
Septembrie 2004 PRECONGRESS COURSE: “ACTUALITATI IN GASTROENTEROLOGIE,
HEPATOLOGIE SI ENDOSCOPIE DIGESTIVA”. The XXVth National Symposium
of Gastroenterology, Hepatology and Gastrointestinal Endoscopy, Constanta,
Romania
13 Octombrie 2004 SIMPOZIONUL “STEATOZA HEPATICA NONALCOOLICA”, SIBIU,
ROMANIA
25 Septembrie 2004 EASL Post-Graduate Course: Liver Transplantation – State of the Art and Novel
Developments, 12th UEGW, Prague, CZECH REPUBLIC
11-12 Noiembrie 2004 Curs de Nutritie Clinica si Metabolism, Poiana Brasov, Romania
13-14 Aprilie 2005 EASL Post-Graduate Course: The Liver Clinic in the Post-Genomic Era, 40 th EASL
Meeting, Paris, France
1 Iunie – 30
Noiembrie 2005
DAAD Scholarship – LIVER TRANSPLANTATION SPECIALISATION,
University Hospital Essen, Germany
12-16 Decembrie
2005
Simpozionul “Clasic si modern in patologia digestiva”, Institutul Clinic Fundeni,
Bucuresti
12-14 Ianuarie 2006 Monothematic Conference: Liver Transplantation for Viral Hepatitis, Paris, Franta
3 Martie 2006 Workshop cu participare internationala cu tema: “Impactul clinic al ecoendoscopiei
diagnostice si terapeutice”, Institutul Clinic Fundeni, Bucuresti
Curriculum Vitae Iacob Maria Speranta
© Uniunea Europeană, 2002-2013 | http://europass.cedefop.europa.eu Pagina 5 / 18
26-30 Aprilie 2006 EASL Postgraduate Course: “Immunological phenomena in hepatitis C in and
outside of the liver”, the 41st Annual Meeting of the European Association for the
Study of the Liver, Vienna, Austria
20-21 Mai 2006 AGA Postgraduate Course: “Recognizing and reducing risk in GI practice”, Digestive
Disease Week, Los Angeles, United States
21 Mai 2006 SSAT (The Society for Surgery of the Alimentary Tract) Postgraduate Course, Los
Angeles, CA, USA.
14 Iunie 2006 Cursul Pre-Simpozion “Curs de Gastroenterologie, Hepatologie si Endoscopie
Digestiva”, Al XXVII-lea Simpozion National de Gastroenterologie, Hepatologie si
Endoscopie Digetiva”, Poiana Brasov – Hotel Piatra Mare
2006 Simpozionul “Sindromul Barrett – de la boala de reflux gastroesofagian la
adenocarcinomul esofagian”, Institutul Clinic Fundeni, Bucuresti
Octombrie 2006 VERUM.EDU seminar on “Basics on Good Clinical Practice for investigators”
Octombrie 2006 ESGE Postgraduate Course: “Endoscopic Oncology; Practice of Endoscopy”, 14th
United European Digestive Week, Berlin, Germany
Octombrie 2006 EASL Postgraduate Course: “Current and Future Therapeutic Options for Viral
Hepatitis”, 14th United European Digestive Week, Berlin, Germany
1 Februarie – 31
Decembrie 2006
Curs deschis la distanta, Universitatea de Medicina si Farmacie “Iuliu Hatieganu”
Cluj-Napoca
11 Aprilie 2007 EASL Postgraduate Course: “The microscope at the bedside”, the 42nd
Annual
Meeting of the European Association for the Study of the Liver, Barcelona, Spain
11-12 Iunie 2007 Third International Symposium on Living Donor Organ Transplantation, Essen,
Germany
27-28 Octombrie
2007
Postgraduate Course: “Recent Advances in Imaging for
Gastrointestinal and Liver Diseases”, 15th United European Digestive Week, Paris,
France
Octombrie 2007 EASL Postgraduate Course:”Portal hypertension”, 15th United European Digestive
Week, Paris, France
23-24 Aprilie 2008 EASL Postgraduate Course: “Complications of portal hypertension”, the 43rd Annual
Meeting of the European Association for the Study of the Liver, Milan, Italy
17-18 Mai 2008 Spring Postgraduate Course: Gastroenterology and Hepatology 2008: Challenges and
Controversies, San Diego CA, USA.
31 Mai- 3 Iunie 2008 The Postgraduate course: “Ultrasound in Gastroenterology and Hepatology”,
EUROSON 2008, Timisoara, Romania
5 Decembrie 2008 Simpozionul “Provocarile terapiei optime in hepatita cronica B”, Institutul National
de Boli INfectioase “Prof Dr Matei Bals”, Bucuresti
17 Iunie 2009 9th ECCO Educational Workshop, Cluj-Napoca, Romania
18 Iunie 2009 Curs precongres. Al XXIX-lea Simpozion National de Gastroenterologie, Endoscopie
Digestiva si Hepatologie, Cluj Napoca
Ianuarie 2009-
Decembrie 2009
Doctoral research fellowship in liver transplantation, University Hospital Essen,
Germany
21-22 Noiembrie
2009
17th UEGW Postgraduate Teaching Programme, Londra, Marea Britanie
14-15 Aprilie 2010 Postgraduate Course:MANAGEMENT OF ACUTE CRITICAL CONDITIONS IN
HEPATOLOGY, 45 Annual Meeting of EASL, Viena, Austria
4 Iunie 2010 Simpozionul National „IBISCUS Bucharest Contrast Enhanced Ultrasound –
Routine Tool in General Imaging”, Bucuresti
Curriculum Vitae Iacob Maria Speranta
© Uniunea Europeană, 2002-2013 | http://europass.cedefop.europa.eu Pagina 6 / 18
9-10 Iunie 2010 Curs Precongres: Al XXX-lea Simpozion National de Gastroenterologie, Endoscopie
Digestiva si Hepatologie, Craiova
24-25 Septembrie
2010
Al II-lea Simpozion National de Boli Inflamatorii Cronice Intestinale cu participare
internationala, Mamaia, Romania
27-30 Septembrie
2010
IASGO CME Postgraduate Course “Liver Transplantation – An interdisciplinary
Approach”, Essen, Germany
22-23 Octombrie
2011
Postgraduate Teaching Programme, 19th UEGW Stockholm, Sweden
4 Noiembrie 2011 AASLD/ILTS Transplant Course: Liver Transplant Immunosuppression: “Does One
Size Fit All?”; 62nd
AASLD Meeting, San Francisco, USA
18-19 Aprilie 2012 EASL Postgraduate Course: Parasitic, “Imported” and Alcoholic Liver Disease,
Barcelona, Spain
14 Iunie 2012 EAGEN Postgraduate Course: “Complication of Inflammation and Infection in the
Gastrointestinal Tract”, Targu Mures, Romania
14-15 Iulie 2012 Postgraduate Weekend, 24th International Congress of the Transplantation Society,
Berlin, Germania
20 Septembrie 2012 27th ECCO Educational Workshop: „ECCO Guidelines”, Sibiu 20 Septembrie 2012
9-10 Aprilie 2013 Clinical Observation Program – Liver Unit, Vall d’Hebron University Hospital
Barcelona, Spain
9-10 Aprilie 2014 EASL-IASL Postgraduate course: “Acute Liver failure/Acute on Chronic liver
failure: perspective of the East and West”, London, United Kingdom
25-26 Aprilie 2014 Up-To-Date in Hepatology, Annual Course – “Viral Hepatitis and Liver Cirrhosis” –
Current Challenges and Future Directions, Bucharest, Romania
26-28 Iunie 2014 “Scoala de vara Medicina Interna-Gastroenterologie”, Paltinis, Romania
6 Martie 2015 ESOT Course: Liver transplantation in HCV positive recipients: facing a new Era
22-23 Aprilie 2015 EASL Postgraduate course – “Metabolic liver disease”, Viena Austria
22 Aprilie 2015 EASL-ILTS-ELITA-LICAGE Post Graduate Course – “Liver Transplant”, Viena,
Austria
27-28 Mai 2015 Up-To-Date in Hepatology, Annual Course – “Portal hypertension and its
complications after Baveno VI Consensus Conference”; “Viral Hepatitis Anno 2015:
Curring the Disease”, Bucharest, Romania
29-30 Mai 2015 EASL Monothematic Conference: “Liver Diseases in resource-limited Settings”
Bucharest, Romania
9 Iunie 2015 Cursul de Gastroenterologie si Hepatologie, Iasi 10-13 iunie 2015
26-28 Iunie 2015 15th International Symposium on Viral Hepatitis and Liver Disease (ISVHLD),
Berlin, Germany
8 Iulie 2015 Current controversies in liver transplantation – Satellite symposium to the ILTS 21st
Annual International Congress, Chicago USA
10 Iulie 2015 Managing HCV in Liver Transplant: Optimizing Success with New DAA Regimens,
Chicago, USA
17-19 Martie 2016 Al 11 lea Simpozion Nicolae Cajal – Mecanisme Moleculare ale Bolilor Acute
si Cronice, Bucuresti, Romania
28-29 Aprilie 2016 3rd UpDate on Hepatology, Course Bucharest 2016, Romania, 28-29 Aprilie
2016, Bucuresti, Romania – „Clinical Challenges, Unmet Needs and Emerging
Therapies in Hepatology”
28-29 Octombrie
2016
Hepatology Academy Preceptorship Program, Universitats Klinikum Frankfurt
Curriculum Vitae Iacob Maria Speranta
© Uniunea Europeană, 2002-2013 | http://europass.cedefop.europa.eu Pagina 7 / 18
11 Noiembrie 2016 AASLD/ILTS Transplant Course “The Next 10 Years: Innovations
Transforming Outcomes in Liver Transplantation” Boston, Massachussets
12-13 Decembrie
2016
Hepatology Academy Preceptorship Center of Excellence Curriculum,
University of Milan, Milan, Italy
29 January 2017 International Hepatitis C Exchange, Paris, France
30-31 January 2017 10th Paris Hepatology Conference – International Conference on the
Management of Liver Diseases
2-5 February 2017 EASL HCC Summit 2017, Geneva, Elvetia
3 Martie 2017 Conferinta „Tratamente inovative in Oncologie – Editia a IIIa – Analiza
moleculara si terapia individualizata in cancer”, Bucuresti, Romania
6-7 Aprilie 2017 4th UpDate on Hepatology, Course Bucharest 2016, Hepatology 2017 – A
panoramic view, Romania, 6-7 Aprilie 2017, Bucuresti, Romania
19 April 2017 PGC on Liver Transplantation: Current challenges in liver transplantation, The
International Liver Congress (ILC) 2017, Amsterdam, Olanda
19 April 2017 PGC on Liver Transplantation: Liver transplantation for viral hepatitis, ILC
2017, Amsterdam, Olanda
19 April 2017 BSS – Hepatic regenerative medicine: Artificial and natural 3D scaffolds for
liver tissue bioengineering, ILC 2017, Amsterdam, Olanda
20 April 2017 PGC – A multidisciplinary approach to patients with liver disease:
Hepatocellular carcinoma, ILC 2017, Amsterdam, Olanda
20 April 2017 PGC – A multidisciplinary approach to patients with liver disease: Non-
alcoholic fatty liver disease, ILC 2017, Amsterdam, Olanda
12-13 May 2017 Hepatology Academy, Standalone Meeting, Paris, Franta
22-24 Iunie 2017 Al 37lea Congres National de Gastroenterologie, Hepatologie si Endoscopie
Digestiva, Bucuresti, Romania
8-9 Septembrie 2017 Pancreatic Fest 2017, Bucharest, Romania
15-16 September
2017
Hope for Cure Vernissage, Budapesta, Hungary
24-27 Septembrie
2017
18th Congress of the European Society for Organ Transplantation, Barcelona,
Spania
28-30 September
2017
9th National Symposium on Inflammatory Bowel Disease, Bucharest, Romania
6-8 October 2017 Congresul National de Radiologie si Imagistica Medicala, Bucuresti, Romania
16-17 October 2017 King’s College Hospital London – Hepatology Academy Perceptorship
10-11 November 2017 Liver Elastography Course, Timisoara, Romania
29 March 2018 Al X-lea Congres al Asociatiei Romtransplant, Bucuresti, Romania
11-15 April 2018 The International Liver Congress, Paris, France
26-27 April 2018 5th UpDate on Hepatology Course – Best Practices in Clinical Hepatology,
Bucharest, Romania
24-26 May 2018 Al 38-lea Congres National de Gastroenterologie, Hepatologie si Endoscopie
Digestiva, Craiova, Romania
2-5 June 2018 Digestive Disease Week 2018: Monumental Developments in Science and
Medicine, Washington, USA
17 Septembrie 2018 Simpozion Stiintific Aniversar – 60 ani de SRGH
19-21 Septembrie
2018
National Congress of the Romanian Association
of Hepato-Bilio-Pancreatic Surgery and Liver Transplantation – 12th
edition,
Cluj Napoca, Romania
3-6 Octombrie 2018 Zilele Institutului Clinic Fundeni 2018
Curriculum Vitae Iacob Maria Speranta
© Uniunea Europeană, 2002-2013 | http://europass.cedefop.europa.eu Pagina 8 / 18
1-4 aprilie 2019 TTT (Train the Trainers) Workshop organized by World Gastroenterology
Organisation (WGO), Bucuresti, Romania
5-6 Aprilie 2019 6th
UpDate on Hepatology Course “From theory to Practice in Liver Diseases,
Bucuresti, Romania
11-14 Aprilie 2019 The International Liver Congress (ILC) 2019, Vienna, Austria
10-11 Aprilie 2019 Postgraduate Course “End stage Liver Disease”, ILC 2019, Vienna, Austria
19-20 Aprilie 2019 Corelatii anatomopatologice si clinice in gastroenterology, Curs-editia I,
Athenee Palace Hilton - Bucuresti
6-8 Iunie 2019 Al 39 lea Congresul National de Gastroenterologie, Hepatologie si Oncologie
Digestiva, Timisoara, Romania
8-10 Iulie 2019 Zilele Institutului Clinic Fundeni 2019
15-18 Septembrie
2019
19th Congress of the European Society for Organ Transplantation, Copenhaga,
Danemarca
19-21 Septembrie
2019
Digestive Endoscopy Cluj 2019
7th
Transylvanian Meeting for Liver Interventions
8-12 Noiembrie 2019 The Liver Meeting, AASLD, Boston, USA
22 Noiembrie 2019 CURS “Amiloidoza… de la A la Z”, Bucuresti
28-29 Februarie 2020 Cursul de Statistica Medicala sustinut la Centrul de Excelenta in Medicina
Translationala, Bucuresti
4 Mai 2020 Management of Transplant Programs during the COVID19 Pandemic- Part II
15 Iunie 2020 The COVID-19 pandemic: Lessons learnt from Italy
25 iunie 2020 COVID-19 & the Liver: Chronic Liver Disease and Transplant
28 iulie 2020 Romania 2030 fara Hepatite - Hepatitele virale in timpul si dupa pandemia
COVID-19
27-29 august 2020 The digital International Liver Congress 2020
13-16 Septembrie
2020
28th International Congress of the Transplantation Society - TTS2020 Virtual
23-26 septembrie
2020
National Congress of the Romtransplant Association – The 11th edition - online
14 august – 14
octombrie 2020
2020 Transplant Hepatology Board Review Course
6-8 noiembrie 2020 7 th UpDate on Hepatology Course Virtual Experience Bucharest 6th-8th November
2020
15-17 noiembrie 2020 ESOT TLJ 2.0 – online experience
Premii, burse,
recunoasterea
meritului
stiintific
Premii Internationale (22)
18-22 Aprilie 2001 Travel Bursary Award, 36th Annual Meeting of European Association for the Study of the
Liver (EASL), Prague, Czech Republic
28 Septembrie – 3
Octombrie 2001
Travel Bursary Award, Falk Symposia No. 124-126, “Progress in Gastroenterology and
Hepatology” Hannover, Germany
Curriculum Vitae Iacob Maria Speranta
© Uniunea Europeană, 2002-2013 | http://europass.cedefop.europa.eu Pagina 9 / 18
1-4 Noiembrie
2001
Certificate of appreciation in recognition of scientific excellence in the free paper (poster)
category: Liver and Biliary Diseases
11th World Congress of the International Association of Surgeons and Gatroenterologists
(IASG), Heraklion, Crete-Greece
23-27 Martie 2002 Bursary Award, The French Days of Digestive Pathology, Nantes, France
18-21 Aprilie 2002 Travel Bursary Award – Best Eastern European Abstract, 37th Annual Meeting of European
Association for the Study of the Liver (EASL), Madrid, Spain
12-17 Octombrie
2004
Travel Bursary Award, Falk Symposia No. 142-144, “Gastroenterology Week Freiburg
2004” Freiburg, Germany
13-17 Aprilie 2005 Young Investigator Full Bursary Award, 40th Annual Meeting of European Association for
the Study of the Liver (EASL), Paris, France
26-30 Aprilie 2006 Young Investigator Full Bursary Award, 41st Annual Meeting of European Association for
the Study of the Liver (EASL), Vienna, Austria
23-24 Martie 2007 Travel Bursary Award, Falk Symposium No. 158, “Intestinal Inflammation and Colorectal
Cancer” Seville, Spain
23-27 Aprilie 2008 Young Investigator Full Bursary Award, 43rd Annual Meeting of European Association for
the Study of the Liver (EASL), Milan, Italy
28 Iunie -1 Iulie
2008
Invited at TTS New KOL Meeting as New Key Opinion Leader (nKOL), Sankt Petersburg,
Russia – “Real time elastography – a noninvasive tool for evaluation of recurrent hepatitis C
following liver transplantation.”
10-14 August 2008 Travel Scholarship,The XXII International Congress of The Transplantation Society, Sydney,
Australia
17 Septembrie
2008
First prize: Falk Workshop “Strategies of Cancer Prevention in Gastroenterology”, Mainz,
Germany for the paper “Early Diagnosis of small hepatocellular carcinoma in cirrhotic
patients using real-time elastography”
17 Septembrie
2008
Travel Bursary Award, Falk Workshop “Strategies of Cancer Prevention in
Gastroenterology”, Mainz, Germany
18-19 Septembrie
2008
Travel Bursary Award, Falk Symposium no 166, “GI Endoscopy – Standards and
Innovations”, Mainz, Germany
20-21 Septembrie
2008
Travel Bursary Award, Falk Symposium no 167, “Liver under constant attack – from fat to
viruses”, Mainz, Germany
17-18 Octombrie
2009
Travel Bursary Award, Falk Symposium no 171, “Liver and metabolic syndrome”,
Hannover, Germany
14-18 April 2010 Young Investigator Full Bursary Award, 45th Annual Meeting of European Association for
the Study of the Liver (EASL), Vienna, Austria
15-19 August 2010 Emerging Economy Travel Award, The XXIII International Congress of The
Transplantation Society, Vancouver, Canada : P37.57 – Survival outcomes following liver
transplantation (SOFT) score - A useful predictor of short term mortality in Romanian
Liver Transplant Program
30 March-3 April
2011
Young Investigator Full Bursary Award, The International Liver Congress 2011 - 46th
Annual Meeting of European Association for the Study of the Liver (EASL), Berlin,
Germany
4-7 Septembrie
2011
Travel Grant City of Glasgow – 15th Congress of the European Society for Organ
Transplantation 22nd
Annual BSHI Conference, Glasgow, United Kingdom
18-22 Aprilie 2012 Registration Bursary - International Liver CongressTM 2012 by EASL, Barcelona, Spain
Curriculum Vitae Iacob Maria Speranta
© Uniunea Europeană, 2002-2013 | http://europass.cedefop.europa.eu Pagina 10 / 18
Premii Nationale (24)
13-16 Iunie 2002 Mentiune pentru lucrarea “Importanta investigatiilor biochimice la pacientii cirotici cu
infectie spontana a lichidului de ascita care suprapun sindrom hepatorenal” prezentata in
cadrul Simpozionului National de Gastroenterologie, Cluj 2002
24-27 Septembrie
2003
Premiul pentru cea mai buna lucrare prezentata in cadrul celui de-al XXIV-lea Simpozion
National de Gastroenterologie, Hepatologie si Endoscopie Digestiva, Craiova 2003:
“Epidemiology of inflammatory bowel disease in adult population in Romania”
24-27 Septembrie
2003
Premiul Poster pentru lucrarea prezentata la cel de XXIV-lea Simpozion National de
Gastroenterologie, Hepatologie si Endoscopie Digestiva, Craiova 2003:“Death predicting
factors on the waiting list for liver transplantation”
1-3 Septembrie
2004
Premiul II – Postere la cel de-al XXV-lea Simpozion National de Gastroenterologie,
Hepatologie si Endoscopie Digestiva, Constanta 2004, pentru lucrarea: “Efficacy of
prophylactic banding ligation of high risk esophageal varices in cirrhotic patients on the
waiting list for liver transplantation”
11-14 Noiembrie
2004
Mentiune pentru Concursul pe teme de Nutritie Clinica organizat de Fresenius Kabi
Romania
15-17 Iunie 2006 Prize for the best oral presentation – section “Viral hepatitis, new techniques, varia”, The
XXVIIth National Symposium of Gastroenterology, Hepatology and Gastrointestinal
Endoscopy, Poiana Brasov, Romania
18-19 Aprilie 2008 Mentiune pentru prezentare sub forma de Poster la Congresul Anual al Asociatiei
Medicale Române, 18-19 Apilie 2008; Academia Romana, Bucuresti –“ Evaluarea
elastografică în timp real a pacienţilor cu hepatită C recurentă posttransplant hepatic”
18-20 Iunie 2008 Premiul II al SRGH pentru lucrarea prezentata la al XXIX-lea Simpozion National de
Gastroenterologie, Hepatologie si Endoscopie Digestiva, Cluj-Napoca 2009: “ ASCA and
ANCA serology in Romanian IBD Patients”.
18-20 Iunie 2008 Premiul II al SRGH pentru posterul prezentat la al XXIX-lea Simpozion National de
Gastroenterologie, Hepatologie si Endoscopie Digestiva, Cluj-Napoca 2009: “The prevalence
of anti-hepatitis B core antibodies in Romania.”
18-20 Iunie 2008 Premiul II al SRGH pentru lucrarea prezentata oral la al XXIX-lea Simpozion National
de Gastroenterologie, Hepatologie si Endoscopie Digestiva, Cluj-Napoca 2009: “ Prediction
of death on large waiting lists for liver transplantation using MELD exceptions.”
27-28 November
2008
Premiul I – Postere. Sesiunea Stiintifica a Institutului Clinic Fundeni si a Institutului de Boli
Cardiovasculare Prof. Dr. C. C. Iliescu: Investigarea profilului de expresie a genelor
implicate in medierea reactiilor inflamatorii la pacientii cu IBD utilizand tehnica MLPA
27-28 Noiembrie
2008 Premiul III pentru prezentarea orala – “Elastografia in timp real – nou marker pentru
evaluarea fibrozei hepatice la pacientii cu hepatita cronica C recurenta post transplant
hepatic”, Scientific Meeting of Fundeni Clinical Institute, 27-28 November 2008,
Bucharest
18 – 20 Iunie 2009 Premiul III pentru prezentarea orala – “Factori de risc ai recurentei carcinomului
hepatocelular dupa tratamentul chirurgical”, The XXIXth National Symposium of
Gastroenterology, Hepatology and Gastrointestinal Endoscopy, Cluj-Napoca, Romania
19-21 Mai 2011 Premiul III al SRGH pentru lucrarea: “Poate fi utilizat polimorfismul genei IL28B pentru
predictia raspunsului virusologic precoce la pacienti cu hepatita recurenta post transplant
Hepatic?”.al XXXI-lea Simpozion National de Gastroenterologie, Hepatologie si Endoscopie
Digestiva
26 Aprilie 2012
Premiul “Eugen Proca”/2011 pentru Stiinte Medicale pentru cartea “Transplantul
hepatic”, Editura Medicala, Bucuresti, 2011, Academia Oamenilor de Stiinta din Romania
Curriculum Vitae Iacob Maria Speranta
© Uniunea Europeană, 2002-2013 | http://europass.cedefop.europa.eu Pagina 11 / 18
ACTIVITATEA
DE
CERCETARE
STIINTIFICA:
PROIECTE DE
CERCETARE-
DEZVOLTARE
TITLU (ACRONIM) Perioa
da Functie
20 Ianuarie 2013 Gala Premiile MEDICA ACADEMICA, Editia a 4a, Premiul oferit de Fundatia “Nicolae
Cajal” pentru cea mai buna realizare in domeniul cercetarii fundamentale in medicina,
Bucuresti
12-15 Iunie 2013 Premiul I al Societatii Romane de Gastroenterologie pentru lucrarea prezentata in cadrul
celui de-al XXXIII-lea Congres National de Gastroenterologie, Hepatologie si Endoscopie
Digestiva, Timisoara 2013: Expresia genica cantitativa a factorilor de transcriptie hepatici
poate fi utilizata pentru predictia recurentei tumorale la pacientii cu hepatocarcinom tratati cu
viza curativa
12-14 Iunie 2014 Premiul SRGH pentru cea mai buna prezentare orala: „Profilul de expresie genica al
genelor specifice celulelor stem/progenitoare hepatice in hepatocarcinom si semnificatiile
prognostice”, Al XXXIV-lea Congres National de Gastroenterologie, Hepatologie si
Endoscopie Digestiva, Oradea
13 Iunie 2014 Diploma de Tanar Cercetator pentru merite deosebite in activitatea de cercetare din partea
Societatii Romane de Gastroenterologie si Hepatologie, Al XXXIV-lea Congres National de
Gastroenterologie, Hepatologie si Endoscopie Digestiva, Oradea
1-4 Aprilie 2015 Premiul „Herbert Beller Barbu” pentru tineri cercetatori pentru lucrarea prezentata in
cadrul celui de-al X-lea Simpozion „Acad. Nicolae Cajal”: “Deletia rs199508964 din exonul
6 al genei IRF5 se coreleaza cu polimorfismul genei Il28B rs12980275 si prezice raspunsul
virusologic sustinut la pacientii cu hepatita recurenta C post-transplant hepatic”.
17 Aprilie 2015 Diploma de Excelenta – cu ocazia aniversarii in Romania a 15 ani de transplant hepatic si
600 de operatii efectuate cu success (2000-2015)
30 Septembrie
2015
Diploma de Excelenta si Recunostinta pt profesionalism si daruire in ingrijirea pacientilor
Institutului Clinic Fundeni - Zilele Institutului Clinic Fundeni 2015
29 Aprilie 2016 Premiul I pentru Posterul prezentat in cadrul cursului 3rd UpDate on Hepatology, Course
Bucharest 2016, Romania, 28-29 Aprilie 2016, Bucuresti, Romania – „Clinical Challenges,
Unmet Needs and Emerging Therapies in Hepatology” cu titlul: „Hepatocyte telomerase
expression in hepatocellular carcinoma and chronic liver disease”
2018 Premiul II pentru Prezentarea Orala „Factori predicivi pentru regresia cirozei hepatice la
un an dupa eradicarea VHC”. In cadrul Mesei Rotunde “Lucrari originale”. Al 38-lea
Congres National de Gastroenterologie, Hepatologie si Endoscopie Digestiva, 24-26 Mai
2018, Craiova, Romania
2019 Premiul I pentru Posterul cu titlul „Metabolic syndrome in liver transplant recipients – The
role of genetic testing and blood based biomarkers” prezentat in cadrul cursului „6th Update
on Hepatology Course”, 5-6 Aprilie 2019, Bucuresti
2019 Winner of the Academic Debate cu titlul ”Controversy 1. Liver transplant beyond Milan
criteria. Pro.” din cadrul celui de al 39-lea Congres National de Gastroenterologie,
Hepatologie si Oncologie Digestiva, 6-8 iunie 2019, Timisoara, Romania
2019 Medalia Jubiliara „1000 de transplanturi hepatice in Romania” din cadrul Congresului
National al Asociatiei Romane de Chirurgie Hepato-bilio-pancreatica si Transplant hepatic,
25-28 Septembrie, Iasi
Curriculum Vitae Iacob Maria Speranta
© Uniunea Europeană, 2002-2013 | http://europass.cedefop.europa.eu Pagina 12 / 18
-INOVARE
OBTINUTE
PRIN
COMPETITIE
PE BAZA DE
CONTRACT/G
RANT
Grant/Proiect National
1.
Proiect VIASAN 324/2004. Rolul evidentei
computerizate a pacientilor in identificarea
potentialilor candidati pentru transplantul hepatic
si in urmarirea dinamicii listei de asteptare
(HEPASIST). Buget: 920000000 ROL
2004-
2006 Cercetator
2.
Proiect VIASAN 322/2004. Rolul manometriei
esofagiene in diagnosticul achalasiei la pacientii
cu disfagie si in evaluarea eficientei
tratamentului endoscopic sau chirurgical al
afectiunii (ROMAC). Buget: 1265000000 ROL
2004-
2006 Cercetator
3.
Proiect VIASAN 428/2004. Evidenta
computerizata prospectiva a pacientilor cu risc
pentru dezvoltarea cancerului colorectal la care
se impune screeningul si supravegherea
(COLOCANS). Buget: 920000000 ROL
2004-
2006 Cercetator
4.
Proiect CEEX 142/2006. Diagnosticul non-
invaziv si markeri de prognostic ai
hepatocarcinomului detectat in leziunile focale
nodulare din ciroza hepatica (PROSONOHEP).
Buget: 1500000 RON
2006-
2008 Cercetator
5.
Proiect CEEX 89/2006. Implicaţii diagnostice şi
prognostice ale aspectului endomicroscopic al
microvascularizaţiei leziunilor premaligne şi
maligne ale tubului digestiv superior
(DIAPROGENDO). Buget: 1500000 RON
2006-
2008 Cercetator
6.
Proiect CEEX 60/2006. Evaluarea fenotipica si
genotipica a pacientilor cu boli inflamatorii
intestinale cronice din Romania si generarea
unui registru biregional computerizat de urmarire
prospectiva (IBDPROSPECT). Buget: 1500000
RON
2006-
2008 Cercetator
7.
Proiect CEEX 65/2006. Potenţialul Terapeutic al
Celulelor Stem Hematopoietice în Afecţiunile
Hepatice (LIVERSTEM). Buget 1500000 RON
2006-
2008 Cercetator
8.
Proiect PNII 42170/2008 ENDONERD Valoarea
endomicroscopiei confocale laser si a
endoscopiei cu magnificatie, in banda ingusta
(NBI), in diagnosticul bolii de reflux
gastroesofagian nonerozive. Buget: 1521600
RON
2008-
2011 Cercetator
Curriculum Vitae Iacob Maria Speranta
© Uniunea Europeană, 2002-2013 | http://europass.cedefop.europa.eu Pagina 13 / 18
9.
Proiect PNII 42169/2008 GENOWIL Valoarea
diagnostica si prognostica a analizei genetice si
corelatii genotip-fenotip la pacientii cu boala
Wilson. Buget: 1963000 RON
2008-
2011 Cercetator
10.
Proiect 42162/2008 BAROFAT (Valoare totala)
Factori predictivi ai raspunsului serologic,
imagistic, imunohistochimic si histologic hepatic
la pacientii cu obezitate morbida si ficat gras
nonalcoolic supusi chirurgiei bariatrice. Buget:
1850000 RON
2008-
2011 Cercetator
11.
Proiect PNII- PCE 125/2011. Molecular
predictors of prognosis following curative
treatment of hepatocellular carcinoma – the
significance of liver stem/progenitor cells genes,
Buget: 1437500 RON
2011-
2016 Cercetator
12.
Proiect finantat prin programul „Cercetare in
domenii prioritare”, mecanismul financiar al
Spatiului Economic European (SEE). EEA-JRP
Romania-Norvegia Nr proiect 4SEE. Stratificarea
pacientilor cu carcinom hepatocelular prin
identificarea unor markeri neinvazivi. Buget:
1125000Eur, Co-finantare privata: 180916 EUR
2014-
2017 Cercetator
13
Proiect POCU/91/4/8/107931, finantat din fonduri
europene nerambursabile, implementat de catre
Institutul Clinic Fundeni din Bucuresti avand titlul
“Program de formare a personalului medical din
România în managementul pacienților infectați
cronic cu virusuri hepatitice B și C - HEPATER”
2018-
2020
Responsabil
curicula VHC
14
Proiect PN-III-P1-1.1-TE-2016-1109 “Effect of
immunosuppression agents on human hepatocyte
and non-parenchymal liver cells
apoptosis”(APOHEPI)
2018-
2020
Director
proiect
15 Proiect de mobilitate pentru cercetatori PN-III-P1-
1.1-MC-2018-1674 2018
Director
proiect
16
Proiect POCU/755/4/9/136208 finantat din fonduri
europene nerambursabile, implementat de catre
Institutul Clinic Fundeni din Bucuresti avand titlul
LIVE(RO)2-SUD: Program regional de prevenire,
screening și diagnostic al pacienților cu boli
hepatice cronice secundare infecțiilor virale cu
virusuri hepatice B/D și C
2020-
2023
Expert
macroregional
Studii multicentrice internationale
Curriculum Vitae Iacob Maria Speranta
© Uniunea Europeană, 2002-2013 | http://europass.cedefop.europa.eu Pagina 14 / 18
1
SR121463B in cirrhotic ascites treatment with
normonatremia: a placebo-controlled dose-
comparison study (NORMO-CAT)
2004 Co-
investigator
2
SR121463B in cirrhotic ascites treatment with
hyponatremia: a placebo-controlled dose-
comparison study (HYPO-CAT) (No LTS5634)
2004 Co-
investigator
3
SR121463B in cirrhotic ascites treatment with
hyponatremia: a single-blind, placebo-controlled,
long-term treatment study (EXPO-CAT) (No
LTS5634)
2004-
2006
Co-
investigator
4
Satavaptan in the prevention of ascites recurrence: a
double-blind, randomized, parallel-group
comparison of satavaptan at 5 to 10 mg daily vs
placebo in the absence of diuretics in patients with
recurrent ascites due to cirrhosis of the liver
(SPARe-2) (EFC 6682) (Phase III)
2006-
2008
Co-
investigator
5
Satavaptan cirrhotic ascites treatment study:a
double-blind, randomized, parallel-group
comparison of treatment with satavaptan at 5 to
10mg daily versus placebo on top of conventional
treatment in patients with ascites due to cirrhosis of
the liver (EFC 4492) (Phase III)
2006-
2008
Co-
investigator
6
Randomized, Multicenter, double-blinded, phase IV
study evaluating the efficacy (as measured by
sustained virological response) and safety of 360µg
induction dosing of Pegasys in combination with
higher Copegus doses in treatment naïve patients
with chronic hepatitis C genotype 1 virus infection
of high viral titer and baseline body weight greater
than or equal to 85kg (Protocol no NV18210A)
2006-
2008
Co-
investigator
7
A phase 3b, Randomized, Double-Blind, Double-
Dummy Study Evaluating the Antiviral Efficacy,
Safety and Tolerability of Tenofovir Disoproxil
Fumarate (DF) Monotherapy versus Emtricitabine
plus Tenofovir DF Fixed-Dose Combination
Therapy in Subjects with Chronic Hepatitis B who
are resistant to Lamivudine – GS-US-174-0121
2008-
2013
Co-
investigator
8
A phase III, randomized, double-blind trial to
evaluate the efficacy, safety and tolerability of
TMC435 vs telaprevir, both in combination with
PegIFN alpha 2a and ribavirin in chronic hepatitis C
genotype 1 infected subjects who were null or
partial responders to prior PegIFN alpha and
ribavirin therapy (ATTAIN Study,
TMC435HPC3001)
2012-
2014
Co-
investigator
Curriculum Vitae Iacob Maria Speranta
© Uniunea Europeană, 2002-2013 | http://europass.cedefop.europa.eu Pagina 15 / 18
9
A randomized, open-labeled study to evaluate the
efficacy and safety of ABT-450/Ritonavir/ABT-267
and ABT-333 co-adminstred with ribavirin
compared to telaprevir co-administred with
pegylated interferon α-2a and ribavirin in treatment-
experienced adults with chronic hepatitis C
genotype-1 virus infection (MALACHITE-II)
2013-
2015
Co-
investigator
10
An International, Multi-Center Study evaluating the
correlation of IL28B genotypes with chronic
hepatitis C disease characteristics and patient
demographics (MV25600)
2011-
2013
Co-
investigator
11
Non-Interventional Cohort Study on the Utilization
and Impact of Dual and Triple Therapies Based on
the Pegylated Interferon for the Treatment of
Chronic Hepatitis C (MV25599)
2012-
2014
Co-
investigator
12
A Phase III, Open-Label Clinical Trial to study the
efficacy and safety of the combination regimen of
MK-5172/MK-8742 versus Sofosbuvir/Pegylated
Interferon/Ribavirin (PR) in treatment-naive and PR
prior treatment failure subjects with chronic HCV
GT1, 4 or 6 infection (MK 5172-077)
2014-
2017
Co-
investigator
13
An Open-Label, Multicenter Study to evaluate long-
term outcomes with ABT-450/Ritonavir/ABT-267
(ABT-450/r/ABT-267) and ABT-333 with or
without ribavirin (RBV) in adults with genotype 1
chronic hepatitis C virus (HCV) infection (TOPAZ-
I) (M14-423)
2014-
2021
Co-
investigator
14
A Study of Glecaprevir (GLE)/Pibrentasvir (PIB) in
Treatment-Naive Adults With Chronic Hepatitis C
Virus (HCV) Genotype 1-6 Infection and
Compensated Cirrhosis (M16-135)
2017-
2018
Co-
investigator
15
A 52-week, placebo-controlled, randomized, Phase
3 study to evaluate the safety and efficacy of
seladelpar in subjects with primary biliary
cholangitis (PBC) and an inadequate response to or
an intolerance to ursodeoxycholic acid (UDCA)
(CB8025-31735)
2019-
2021
Co-
investigator
16
A Multicenter, Randomized, Double-Blind,
Placebo-Controlled Phase III Study to Evaluate
the Efficacy and Safety of Elafibranor in Patients
with Nonalcoholic Steatohepatitis (NASH) and
fibrosis (GFT505-315-1)
2017-
2020
Co-
investigator
17
A PHASE 3, MATRIX DESIGN,
PARTIALLY DOUBLE-BLIND,
RANDOMIZED STUDY OF THE
EFFICACY AND SAFETY OF 50 MG
LONAFARNIB/ 100 MG RITONAVIR BID
WITH AND WITHOUT 180 MCG PEG IFN-
2020-
2022
Co-
investigator
Curriculum Vitae Iacob Maria Speranta
© Uniunea Europeană, 2002-2013 | http://europass.cedefop.europa.eu Pagina 16 / 18
ALFA-2A FOR 48 WEEKS COMPARED
WITH PEG IFN-ALFA-2A MONOTHERAPY
AND PLACEBO TREATMENT IN
PATIENTS CHRONICALLY INFECTED
WITH HEPATITIS DELTA VIRUS BEING
MAINTAINED ON ANTI-HBV
NUCLEOS(T)IDE THERAPY (D-LIVR
PROTOCOL NUMBER: EIG-LNF-01
Studii multicentrice nationale
1
Observational, retrospective cohort study to
evaluate pretreatment and on treatment predictors of
response to peginterferon alfa and ribavirin therapy
in chronic viral Hepatitis C in real life medical
practice in Romania (HERO 1) – protocol ML
21909
2008-
2009
Co-
investigator
PUBLICATII
Indice Hirsch ISI Web of Science Core Colection (22.03.2021): 19
Nr Citari ISI Web of Science (22.03.2021): citari totale 1099
Curriculum Vitae Iacob Maria Speranta
© Uniunea Europeană, 2002-2013 | http://europass.cedefop.europa.eu Pagina 17 / 18
Lista Completa de Lucrari:
I. Lista lucrarilor semnificative:
1. Speranta Iacob, Vito R. Cicinnati, Philip Hilgard, Razvan A. Iacob, Liana S. Gheorghe, Irinel
Popescu, Andrea Frilling, Massimo Malago, Guido Gerken, Christoph E. Broelsch, Susanne
Beckebaum. Predictors of graft and patient survival in HCV recipients - model to predict HCV
cirrhosis following liver transplantation. Transplantation 2007; 84:56-63
2. Cicinnati VR, Iacob S, Klein CG, Baba HA, Sotiropoulos GC, Hilgard P, Erim Y, Broelsch CE,
Gerken G, Beckebaum S. Ribavirin with either standard or pegylated interferon to treat recurrent
hepatitis C after liver transplantation. Aliment Pharmacol Ther 2007; 26:291-303
3. Speranta Iacob, Liana Gheorghe, Doina Hrehoret, Gabriel Becheanu, Vlad Herlea, Irinel Popescu.
Pegylated Interferon α-2a and Ribavirin Combination Therapy in HCV Liver Transplant
Recipients. Experience of 7 Cases. J Gastrointestin Liver Dis 2008; 17:165-172
4. Iacob S, Gheorghe L, Iacob R, Gheorghe C, Hrehoret D, Popescu I. MELD exceptions and new
predictive score of death on long waiting lists for liver transplantation. Chirurgia (Bucur)
2009;104: 267-273
5. Beckebaum S, Iacob S, Klein CG, Dechêne A, Varghese J, Baba HA, Sotiropoulos GC, Paul A,
Gerken G, Cicinnati VR. Assessment of Allograft Fibrosis by Transient Elastography and
Noninvasive Biomarker Scoring Systems in Liver Transplant Patients. Transplantation.
2010;89:983-93
6. Beckebaum S, Iacob S, Sweid D, Sotiropoulos GC, Saner F, Kaiser G, Radtke A, Klein CG, Erim
Y, de Geest S, Paul A, Gerken G, Cicinnati VR. Efficacy, safety, and immunosuppressant
adherence in stable liver transplant patients converted from a twice-daily tacrolimus-based
regimen to once-daily tacrolimus extended-release formulation. Transpl Int 2011;24:666-75
7. Iacob S, Cicinnati VR, Dechêne A, Lindemann M, Heinemann FM, Rebmann V, Ferencik S,
Sotiropoulos GC, Popescu I, Horn PA, Gerken G, Paul A, Beckebaum S. Genetic, immunological
and clinical risk factors for biliary strictures following liver transplantation. Liver Int. 2012;
32(8):1253-61
8. Xu L, Beckebaum S, Iacob S, Wu G, Kaiser GM, Radtke A, Liu C, Kabar I, Schmidt HH, Zhang
X, Lu M, Cicinnati VR. MicroRNA-101 inhibits human hepatocellular carcinoma progression
through EZH2 downregulation and increased cytostatic drug sensitivity. J Hepatol. 2014;
60(3):590-8
9. Iacob S, Cicinnati VR, Lindemann M, Heinemann FM, Radtke A, Kaiser GM, Kabar I, Schmidt
HH, Baba HA, Beckebaum S. Donor-Specific Anti-HLA Antibodies and Endothelial C4d
Deposition-Association With Chronic Liver Allograft Failure. Transplantation. 2015;
99(9):1869-75
10. Iacob S, Ester C, Lita M, Ratziu V, Gheorghe L. Real-life perception and practice patterns of
NAFLD/NASH in Romania: results of a survey completed by 102 board-certified
gastroenterologists. J Gastrointestin Liver Dis. 2016;25(2):183-90
11. L. Gheorghe, I. Sporea, S. Iacob, R. Şirli, A. Trifan, D. Dobru, M. Diculescu, C. Stanciu, O. Pascu,
M. Acalovschi, C. Brisc, C. Cijevschi, C. Gheorghe, Z. Spârchez, I. Rogoveanu, D. Dumitrascu.
Position paper on treatment of hepatitis C in Romania, 2017. Part one. J Gastrointestin Liver Dis.
2017;26(2):171-81 (Corresponding author)
12. Gheorghe L, Sporea I, Iacob S, Sirli R, Trifan A, Diculescu M, Stanciu C, Pascu O, Acalovschi M,
Brisc C, Cijevschi C, Gheorghe C, Spârchez Z, Rogoveanu I, Dobru D, Dumitrascu DL. Position
Paper on Treatment of Hepatitis C in Romania 2017. Part Two. J Gastrointestin Liver Dis.
2017;26(3):309-317. (Corresponding author)
Curriculum Vitae Iacob Maria Speranta
© Uniunea Europeană, 2002-2013 | http://europass.cedefop.europa.eu Pagina 18 / 18
13. Gheorghe L, Iacob S, Curescu M, Brisc C, Cijevschi C, Caruntu F, Stanciu C, Simionov I, Sporea
I, Gheorghe C, Iacob R, Arama V, Sirli R, Trifan A. Real-Life Use of 3 Direct-Acting Antiviral
Regimen in a Large Cohort of Patients with Genotype-1b HCV Compensated Cirrhosis. J
Gastrointestin Liver Dis. 2017;26(3):275-281. (Corresponding author)
14. Dorobantu B, Popescu I, Dima S, Nastase A, Iacob S. Molecular Biomarkers as Predictors for
Biliary Complications Following Liver Transplantation. A Prospective Study. J Gastrointestin
Liver Dis. 2017;26(3):253-259.
15. Iacob S, Cerban R, Pietrareanu C, Ester C, Iacob R, Gheorghe C, Popescu I, Gheorghe L. 100%
Sustained Virological Response and Fibrosis Improvement in Real-Life Use of Direct Acting
Antivirals in Genotype-1b Recurrent Hepatitis C following Liver Transplantation. J Gastrointestin
Liver Dis. 2018;27(2):139-144
16. Iacob S, Ghioca M, Csiki IE, Tomescu D, Droc G, Hrehoret D, Brasoveanu V, Pietrareanu C, Iacob
R, Gheorghe C, Popescu I, Gheorghe L. Pre and post-liver transplant outcome of cirrhotic patients
with acute on chronic liver failure. Medicine 2020; Vol:No 44(e22419)
II. Teza de Doctorat:
Titlul Tezei de Doctorat: „Hepatita recurenta C posttransplant hepatic – strategii terapeutice si factori
asociati cu recurenta severa”. Coordonator: Prof. Dr. Irinel Popescu
III. Carti si Capitole din Carti: 31
IV. Articole /studii in extenso publicate in reviste cotate ISI: 67
V. Articole /studii publicate in extenso in jurnale indexate BDI: 27
VI. Articole /studii publicate in extenso cu caracter educational: 12
VII. Rezumate ale lucrarilor prezentate la conferinte internationale de specialitate, publicate in reviste
cotate ISI: 301
VIII. Rezumate publicate in Reviste/volumele unor manifestari stiintifice cu ISBN/ISSN: 74
IX.Conferinte invitate la manifestari stiintifice Internationale si Nationale: 55
X.Alte lucrari si contributii Stiintifice.
A.Prezentari orale la manifestari stiintifice internationale: 29
B.Prezentari orale la manifestari stiintifice nationale: 113
C.Prezentari sub forma de poster: 388