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Onderzoeksgroep: STATISTIEK 2008
A Identiteit van de deelnemende onderzoekers Aerts Marc, Alonso Ariel, Beunckens Caroline, Bijnens Luc, Birhanu Teshome Ayele,
Bollaerts Kaatje, Braekers Roel, Bruckers Liesbeth, Burzykowski Tomasz, Buyse Marc, Callaert Herman, Castro Sanchez Yovanna Amparo, Cortiñas Abrahantas José, Creemers An, Del Fava Emanuele, Duchateau Luc, Faes Christel, Gaddah Auguste, Geys Helena, Girma Minalu, Gitome Arthur, Goeyvaerts Nele, Lin Dan, Haldermans Philippe, Hens Niel, Jacobs Tom, Jansen Ivy, Janssen Paul, Kadankova Tetyana, Kasim Adetayo, Laenen Annouschka, Lesaffre Emmanuel, Litière Saskia, Maringwa John, Massonnet Goele, Molenberghs Geert, Namata Harriet, Pramana Setia, Pryseley Assam Nkouibert, Qi Zhu, Renard Didier, Rizopoulos Dimitris, Serroyen Jan, Skhedy Ziv, Sotto Cristina, Thijs Herbert, Tilahun Eshete Abel, Valkenborg Dirk, Van Effelterre Thierry, Van Keilegom Ingrid, Van Rompaye Bart, Van Sanden Suzy, Veraverbeke Noël, Verbeke Geert, Weyler Joost, Winters Bart, Wouters Kristien, Wouters Luc.
B Titel(s) van het (de) onderzoeksproject(en)
a. Mathematische statistiek
ÄK Biostatistiek
C Beschrijving van de ontwikkelde onderzoeksactiviteit(en) per project
- Research on statistical education (HC)
- Resampling, goodness of fit (NV, PJ, Jan Swanepoel)
- Extension of Koziol-Green model (RB, NV)
- Copula process with covariates (NV)
- Empirical likelihood for non smooth criterion function (NV, Ingrid Van Keilegom, Elisa
Molanes)
- Weak convergence for copula estimator (NV, Irène Gijbels, Marek Omelka)
- Risk theory (NV, Stéphane Loisel, Claudio Macci)
- Difference of compound Poisson and compound renewal process (TK)
- Two-boundary characteristics (TK)
- Queueing systems with limited waiting room and applications (TK)
- Extension of the Koziol-Green model by introducing a copula on lifetime and censoring time.
Non- and semiparametric estimation of the copula. Goodness-of-fit for the copula family
(RB, AG)
- Copula model for association between error and covariate in homoscedastic regression (RB,
Ingrid Van Keilegom)
- A zero-inflated Cox regression model for left-censored data. (RB, Paul Markel)
- Semi-competing risk model with fixed covariate. Copula-graphic estimation for the
conditional distribution of the smallest lifetime (RB, NV)
- Two-stage estimation in copula models: methodology and udder infection example (GMa, PJ,
Luc Duchateau)
- The choice of the copula using pseudo-likelihood ratio tests (GMa, PJ, Luc Duchateau)
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- General goodness-of-fit test for four-dimensional copula models (GMa, PJ)
- Spatial and temporal frailty models (PJ, Luc Duchateau, Yehenew Getachew (Jimma
University))
- Frailty models and general linear models with time-varying coefficients (PJ, Ingrid Van
Keilegom, Catherine Legrand)
- Study of bias in frailty models (PJ, Dimitris Karlis)
- Fitting frailty models via transformation: the continuous case (PJ, Ricardo Cao, Ignacio Lopez
de Ullibarri)
- Missing data and sensitivity analysis (GM, MA, HT, IJ, CB, CS, AC, Geert Verbeke, Dimitris
Rizopoulos, Sypridoula Tsonaka, Kristel Van Steen, Els Goetghebeur, Michael G. Kenward,
Stijn Vansteelandt)
- Missing data in clinical trials (GM, Michael G. Kenward, Raymond J. Caroll, Craig Millinckrodt,
CB, IJ, CS)
- Pattern-mixture models (GM, HT, Michael G. Kenward, CB, IJ)
- Surrogate markers (GM, TB, HG, Fabián Tibaldi, JC, AA, ZS, Tony Vangeneugden, Didier
Renard, AT, PA)
- Neuron synchronization (Carmen Cadarso, HG, GM, AA, CF)
- Logistic mixed models in item response theory (GM, Geert Verbeke, Paul De Boeck, Dirk
Smits, Edward Ip, Yuri Goegebeur)
- Models for discrete repeated measures (GM, Geert Verbeke)
- Small-sample degrees of freedom (GM, CF, MA, Geert Verbeke, Michael G. Kenward)
- Methods for clustered data (MA, HG, CF, GM)
- Models for infectious diseases (MA, ZS, GM, NH)
- Methods for optimization in statistics (GM, Geert Verbeke, Iven Van Mechelen, Francis
Tuerlinckx)
- Psychometric methods in clinical studies (GM, AL, AA, Tony Vangeneugden)
- Combined longitudinal-overdispersed models (GM, Geert Verbeke, Clarice Demétrio, Tony
Vangeneugden, Afranio Vieira)
- Psueo-likelihood for incomplete data (GM, Geert Verbeke, BT, Michael G. Kenward)
- Topics in modeling infectious diseases (MA, NH, ZS, CF, JC, NG, KB, YC, HN, Pierre Van
Damme, Philippe Beutels, Heidi Theeten, Ogenjimi Benson, Koen Van Herck, Elke Leuridan,
Gaelle Boulet, John-Paul Bogers, Olivier Lejeune (UA), Koen Mintiens, Stefan Roels, Yves
Vanderstede, Estelle Méroc (Centrum voor Onderzoek in de Diergeneeskunde en Argonomie),
Dirk Berkvens, Nico Speybroeck (Instituut voor Tropische Geneeskunde), Patrick Cras (UA),
Claude Saegerman (ULiège), Peter Theunis, Jacco Wallinga (RIVM, Bilthoven, NL))
- Topics in microbial risk assessment, Zoonotic diseases (e.g. Salmonella), Vectorborne
diseases (e.g. Bluetongue) and food safety (MA, CF, ZS, SL, JC, KB, HN, Koen Mintiens, Ides
Boone, Yves Van der Stede en Stefan Roels (Centrum voor Onderzoek in de
Diergeneeskunden en Agrochemie), Stefaan Ribbens en Jeroen Dewulf (Ugent), Koen
Grijspeerdt (Instituut voor landbouw- en Visserijonderzoek), Peter Teunis (RIVM, Bilthoven,
NL)
- Topics in model selection (MA, NH, Jeffrey Simonoff (New York University)
- Topics in correlated frailty models (MA, NH, GM, Andreas Wienke (University Halle-
Wittenberg))
- Topics in missing data (MA, GM, HT, NH, IJ, AC, Geert Verbeke, Mike Kenward)
- Topics in safety assessment of lactobacilli (MA, NH, GiM, GM, Vanessa Vankerckhoven,
Hermans Goossens (UA))
- Topics in diagnosis of M. pneumoniae infections (MA, NH, GM, Katherine Loens, Greet Ieven,
Herman Goossens (UA))
P
- Dealing with various issues when modelling infectious diseases (NH, MA, KB, AC, CF, NG,
GiM, HN, ZS, Philippe Beutels, Joke Bilcke, Olivier Lejeune, Benson Ongunjimi, Pierre Van
Damme (UA))
- Modelling the force of infection from seroprevalence data: to monotonize or not to
monotonize ? (NH, MA, Andrea Kvitkovicova, David Hlubinka (Prague), Pierre Van Damme,
Philippe Beutels (UA))
- Elucidation on country-specific differences of the sero-epidemiology of B19 and VZV in five
different European countries (NH, MA, ZS, Nigel Gay, John Edmunds, Alessia Melagaro
(Heatlh Protection Agency))
- Caregiver concerns about the number of vaccine injections and willingness to pay to reduce
them (NH, MA, Heidi Theeten, Pierre Van Damme, Philippe Beutels (UA), Corinne
Vandermeulen, Mathieu Roelants, Karel Hoppenbrouwers (KULeuven))
- Modelling cell and matrix adhesion for bacterial infectious (Vanessa Van Kerkhoven,
Katherine Loens, Greet Ieven and Herman Goossens (UA), NH, MA, GiM)
- Modelling pandemic influenza: the impact on Flanders (NH, MA, CF, Samuel Xavier de Souza,
Elke Moons, Davy Jansen, Philippe Beutels (UA), Marc Van Ranst, Pieter Maes (KULeuven),
Ignace Glorieux (VUB))
- Penalized splines methodology (CF)
- Pseuo-likelihood estimation method (CF)
- Infectious disease modeling (CF)
- Spatio-temporal spread of infectious diseases (CF)
- Spatial distribution of Bluetongue in Belgium, Germany and the Netherlands (CF)
- Correcting the apparten herd-prevalence based on the diagnostic test characteristics for
tests applied to individuals (CF)
- Using empirical social contact data to model person to person infectious disease
transmission: an illustration for variacella (NG, NH, MA, Pierre Van Damme, Philippe Beutels)
- Mining social mixing patterns for infectious disease models based on a two-day population
survey in Belgium (NG, NH, MA, ZS, Pierre Van Damme, Philippe Beutels)
- Estimating infectious disease parameters for data on social contact and serological status
(NG, NH, Benson Ogunjimi, MA, ZS, Pierre Van Damme, Philippe Beutels)
- Parvovirus B19 in five European countries; disentangling the sociological and microbiological
mechanisms underlying infectious disease transmission (NG, John Edmunds, MA, Philippe
Beutels)
- Modeling infectious diseases: HiV, Amsterdam Cohort Studies (ACS, MA, NH, ZS)
- Diagnostic tools for misspecification in mixed models (SL, AA)
- Dose-response study of microarray experiments: investigating the dose-response
relationship, dose-response curve shapes using isotonic regression, parametric modeling,
and information theory for model selection, Bayesian method, multiple contrast tests (DL,
SP, AK, ZS, An de Bondt, Willem Talloen, Hinrich Goelhmann, Luc Bijnens)
- Selection and evaluation of genomic biomarkers: identifying two types of biomarkers,
prognostic and therapeutic using the joint model and hierarchical Bayesian modeling
approach, and constructing a joint biomarker profile for the selected biomarkers (DL, AT, ZS,
An de Bondt, Willem Talloen, Hinrich Goehlmann, Luc Bijnens)
- Analysis of microarray data: biomarkers and analysis based on Laplace distribution (SV, DL,
AT, AK, AG, SP)
- I/NI calls: a latent variable approach (AK, DL, SV, ZS)
- Order restricted clustering for dose-response microarray experiment (AK, DL, ZS)
- Modeling dose-reponse trends in microarray experiments: hierarchical Bayesian approach
(AK, DL, ZS)
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- Gene signatures with bivariate expression (AK, DL, SV, JC and ZS)
- Fractional polynomial mixed models, Linear discriminant analysis, Flexible discriminant
analysis, Mixture discriminant analysis, Model average, Mutual information, Pseuo-Likelihood
Modeling, Functional Discriminant Analysis (KW, JC, GM)
- Estimating kinase activity in early drug development proteomics experiments using mixed
models (AG, AK, DL, SV, ZS, Matthias Versele, Willem Talloen, Tim Perera, Luc Bijnens
(Janssen Pharmaceutica))
- Molecular phylogenetic analysis on viral sequences and estimation of skyline plots (AG, DL,
SP, ZS)
- Normalization of microarrays. Using microarray, peptide data for the prediction of dose-
response data (PH, ZS, SV, DL, SP)
- Methods of the analysis of microarray (TB, SV, ZS)
- Methods of the analysis mass-spectrometry data (TB, DV, QZ, IJ, AK)
- Validation of surrogate endpoints in multiple randomized clinical trials (TB, Marc Buyse)
- Modelling prevalence and force of infection on case notification and serological data (KB, MA,
ZS, NH, HN, CF, Frank Boelaert (EFSA))
- Ontwikkeling van een methodlogie voor de kwantitatieve beoordeling van zonotische risico’s
toegepast op het model Salmonella bij varkens (KB, MA, ZS, UL: George Daube, UGent:
Lieven De Zutter; ILVO: Koen Grijspeerdt; CODA: Koen Mintiens)
- P-splines regression with shape contraints (KB, MA; University Rotterdam: Paul Eilers)
- Nonlinear mixed effects modelling: IVIVC modelling; pharmacology (TJ, GM, A. Dunne
(University College, Dublin), R. Straetemans (Janssen Pharmaceutica, Beerse))
- Incomplete longitudinal data: generalized mixed models, (weighted) generalized estimating
equations, multiple imputation, sensitivity analysis, local influence, pattern-mixture models,
shared-parameters models, latent-class models (CB, CS)
- Surrogate marker validation and selection and evaluation of genomic biomarkers (AT, GM,
ZS, TB, Marc Buyse, AA, JC, DL)
- Genetic distance, likelihood-based estimation repreduction number, transmission network
(SP, AG, DL, ZS)
- Nonlinear models, isotonic regression, tests for monotone trend, ratio tests, Graphical Use
Inference (SP, PH, DL, ZS, An de Bondt, Willem Taloen, Hinrich Goehlmann, Luc Bijnens
(Janssen Pharmaceutica))
- Supervised learning techniques, classification of psychotropic drugs and gait patterns (JC,
KW)
- Aternative methods to evaluate surrogacy, using supervised learning methodology (JC, GM,
ZS)
- Solution for separation problems in logistic regression with clustered data (JC)
- Survival analysis, clustered interval censored data (JC)
- Identification of risk groups using mixed modelling techniques (JC)
- Use of mixture models to estimate seroprevalence and, possibly, the force of infection in
some infectious diseases, directly from antibody levels, in absence of a standard cut-off
point. Study of the co-infection between HiV and HCV in injected-drugs users, using both
cross-sectional and longitudinal data (ED, Infectious Disease Modelling Group UH, P.
Manfredi (Pisa), G. Scalia Tomba (Roma), Mirjam Kretzschmar (Utrecht), Peter Theunis
(RIVM, Bilthoven))
- Bayseian modelling; Proteomics; Mass-spectrometry data; Detection of overlapping peptides
(IJ, QZ, TB, DV, AK)
- Protein-protein interaction networks; Modelling of sampling distributions (IJ, Frank Neven,
Peter Boyen, Dirk Valkenborg)
R
- Psychiatric epidemiology: uncovering groups of similar patients in complex data sets with
repeated measurements (LB, GM, AL)
- Information-theory based surrogate marker evaluation for time-to-event clinical and
surrogate endpoints (PA, AT, AA, TB, GM)
- Information-theory based surrogate marker evaluation for time-to-event clinical endpoint
and longitudinal surrogate endpoints (PA, AT, AA, TB, GM)
- Applying concepts of generalizability theory on data from experimental pain studies to
investigate reliability (PA, Edouard Ledent, Lars Arendt-Nielsen)
- Investigating the performance of hierarchical formulations of marginal models for non-
Gaussian data for estimating negative intraclass correlations. (PA, GM)
- Biomarker discovery from COFRADIC MALDITOF-MS data: deconvolution and feature
extraction for mass spectral serum profiles (DV, TB, Janne Lahtiö (Karolinska Institute),
Koen Kas, (Pronota))
- A model based method for predicting the isotropic distribition of peptides (DV, TB, IJ)
- Missing observations in mass spectrometry data (DV, TB, IJ)
- A discrete-time Markov-model for estimating the relative abundance in enzymatic 18O stable-
isotope labeled MALDI-TOF mass spectra. (DV, TB, Koen Kas (Pronota), Etienne Waelkens
(KULeuven))
- Methods to detect overlapping peptide peaks in m/z-dimension. (DV, TB, IJ, AK)
- MCMC-based estimation for continuous longitudinal data with missingness (CS, CB, GM, Mike
Kenward)
- Sensitivity analysis (CS, CB, GM, Geert Verbeke)
- Marginalizing pattern-mixture models for categorical data with missingness (CS, CB, GM, IJ,
Geert verbeke)
- Extensions of latent class mixed models (CS, CB, GM)
- Meaningful parametrizations for missing data models (CS, GM, Geert Verbeke)
- Reliability estimation in clinical trial data with repeated measurements (AL, AA, GM, Tony
Vangeneugden)
- Minimal Psychiatric Data: development of a new registration instrument (AL, GM)
- Missing data: a new method to handle missing covariates (AC, MA, NH)
- Shared parameter models and MAR (AC, NH, MA, Geert Verbeke, Michael Kenward)
- Sensitivity analysis for the shared parameter model (AC, GM, NH, MA, Geert Verbeke,
Michael Kenward)
- Medical costs in infectious diseases (pneumococcal disease) (AC, MA, NH, ZS, Philippe
Beutels)
- Psychometrics (AA, GM, AL)
- Reliability of rating scales (AA, GM, AL)
- Miss-specified random effects distribution (AA, GM, SL)
- Generalized linear mixed models (GLMM) (AA, GM, SL)
- Diagnostic tools for GLMM (AA, GM, SL)
- Biomarkers (AA, GM, Didier Renard, Christelle Darstein)
- Surrogate marker validation (AA, GM, AP, AT)
- Survival data and measures of association (AA, GM, AP, AT)
- Investigating associations between behavior and corticosterone levels in rats using surrogate
marker validation technique (JM)
- Analysis of cross-over cardiovascular safety experiments (JM)
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D Mededelingen van resultaten van het onderzoekswerk
1 Doctoraats- en aggregaatsthesissen
11 In de onderzoeksgroep behaalde doctoraten
Dan Lin
Classification, dose-response modelling, and the evaluation of biomarker in a microarray
setting. 28 maart 2008. Supervisor: Tomazs Burzykowski
Tony Vangeneugden
Psychometric validation methodology to longitudinal clinical trial data. 19 mei 2008.
Supervisor: Geert Molenberghs
Goele Massonnet
Contributions to frailty and copula modelling with applications to clinical trials and dairy
cows data. 8 september 2008. Supervisor: Paul Janssen
Kristien Wouters
Classification methods for multi-class multivariate longitudinal data. 9 september 2008.
Supervisor: Geert Molenberghs
Suzy Van Sanden
Statistical methods for microarray-based analysis of gene-expression, classification, and
biomarker validation. 11 september 2008. Supervisor: Tomasz Burzykowski
Dirk Valkenborg
Statistical methods for the analysis of high-resolution mass spectrometry data. 12
september 2008. Supervisor: Tomasz Burzykowski
Harriet Namata
Flexible statistical models for microbial risk assessment and infectious diseases. 15
september 2008. Supervisor: Marc Aerts
John Maringwa
Flexible modelling techniques and use of historical controls in animal studies. 26
september 2008. Supervisor: Helena Geys
Annouschka Laenen
Psychometric validation of continuous rating scales from complex data. 12 december
2008. Supervisor: Geert Molenberghs
12 (Co)promoties van doctoraten, niet behaald aan de UHasselt
13 Lidmaatschappen van jury's van buitenlandse doctoraten
Noël Veraverbeke
2 april 2008. Charles University, Prague, Czech Republic. Jurylid voor doctoraat van
David Kraus. “Neyman’s smooth test in suurvival analysis” (promotor: Peter Volf)
Tomasz Burzykowski
5 september 2008. Karolinkska Institute, Stockholm, Sweden. Jurylid voor doctoraat van
ChuenSeng Tan “Statistical methods for biomarker discovery in proteomics” (promotor:
Yudi Pawitan)
T
14 Lidmaatschappen van jury's van binnenlandse doctoraten
Noël Veraverbeke
19 mei 2008. Vrije Universiteit Brussel. Jurylid voor doctoraat van Julia Dony
“Nonparametric regression estimation: an empirical process approach to uniform
bandwidth consistency of kernel estimators and conditional U-statistics”. (Promotor: Uwe
Einmahl)
Geert Molenberghs
5 mei 2008. Universiteit Antwerpen. Co-supervisor van doctoraat van Willem Aelvoet
“Ambtelijke registraties voor een evaluatief gezondheidsbeleid. Aspecten van
beleidsonderbouwing op landelijk, intermediair en lokaal niveau” (promotor: Marc Van
Sprundel)
5 augustus 2008. KULeuven. Jurylid voor doctoraat van Dimitris Rizopoulos (promotor:
Geert Verbeke)
5 augustus 2008. KULeuven. Jurylid voor doctoraat van Spyridoula Tsonaka (promotor:
Geert Verbeke)
Marc Aerts
5 augustus 2008. KULeuven. Jurylid voor doctoraat van Dimitris Rizopoulos (promotor:
Geert Verbeke)
5 augustus 2008. KULeuven. Jurylid voor Spyridoula Tsonaka (promotor: Geert Verbeke)
Paul Janssen
19 december 2008. UCL, Louvain-la-Neuve. Jurylid voor doctoraat van Bianca Teodorescu
“General conditional linear models with time-dependent coefficients under censoring and
truncation (promotor: Ingrid Van Keilegom)
2 Wetenschappelijke publicaties
Internationale wetenschappelijke publicaties
20 Gepubliceerde artikels in internationale tijdschriften (opgenomen in de JCR1 of
in een door de Onderzoeksraad erkende alternatieve tijdschriftenlijst)
Wang, L. and Veraverbeke, N. (2008). MSE superiority of Bayes and empirical Bayes
estimators in two generalized seemingly unrelated regressions. Statistics and Probability
Letters, 78, 109-117.
Braekers, R. and Veraverbeke, N. (2008). A conditional Koziol-Green model under dependent
censoring. Statistics and Probability Letters 78, 927-937.
==============================================1 JCR : Journal Citation Reports (als afzonderlijke publicatie van de Science Citation Index en van de Social Sciences Citation Index, opgemaakt door het Institute for Scientific Information).
= U
Omelka, M., Gijbels, I. and Veraverbeke, N. (2008). Improved kernel estimation of copulas:
weak convergence and goodness-of-fit testing. Annals of Statistics (to appear).
Molanes, E.M., Van Keilegom, I. and Veraverbeke, N. (2008). Empirical likelihood for non-
smooth criterion functions. Scandinavian Journal of Statistics (to appear).
Verbeke, G., Molenberghs, G. and Beunckens, C. (2008). Formal and informal model selection
with incomplete data. Statistical Science, 23, 201-218.
Vloeberghs, E., Van Dam, D., Frank, F., Serroyen, J., Molenberghs, G., Staufenbiel, M., and De
Deyn, P.P. (2008). Altered ingestive behavior, weight changes and intact olfactory sense
in an APP overexpression model. Behavioral Neuroscience, 122, 491-497.
Alonso, A. and Molenberghs, G. (2008). Evaluating time to cancer recurrence as a surrogate
marker for survival from an information theory perspective. Statistical Methods in Medical
Research, 17, 497-504.
Litière, S., Alonso, A., Molenberghs, G. and Geys, H. (2008). The impact of a misspecified
random-effects distribution on the estimation and performance of inferential procedures
in generalized linear mixed models. Statistics in Medicine, 27, 3125-3144.
Vangeneugden, T., Molenberghs, G., Laenen, A., Alonso, A. and Geys, H. (2008).
Generalizability in non-Gaussian longitudinal clinical trial data based on generalized linear
mixed models. Journal of Biopharmaceutical Statistics, 18, 1-22.
Faes, C., Molenberghs, G., Geys, H., Aerts, M., Cadarso-Suarez, C., Acuña, C., and Cano, M.
(2008). A flexible method to measure synchrony in neuronal firing. Journal of American
Statistical Association, Case Studies, 103, 140-161.
Jansen, I. and Molenberghs, G. (2008). A flexible marginal modeling strategy for non-
monotone missing data. Journal of the Royal Statistical Society, Series A, 171, 347-373.
Tilahun, A., Assam, P., Alonso, A. and Molenberghs, G. (2008). Information theory-based
surrogate marker evaluation from several randomized clinical trials with binary endpoints,
using SAS. Journal of Biopharmaceutical Statistics, 18, 326-341.
Molenberghs, G., Beunckens, C., Sotto, C. and Kenward, M.G. (2008). Every missing not at
random model has got a missing at random counterpart with equal fit. Journal of the
Royal Statistical Society, Series B, 70, 371-388.
Molenberghs, G., Burzykowski, T., Alonso, A., Assam, P., Tilahun, A. and Buyse, M. (2008).
The meta-analytic framework for the evaluation of surrogate endpoints in clinical trials.
Journal of Statistical Planning and Inference, 138, 432-449.
Wouters, K., Cortiñas, J., Molenberghs, G., Ahnaou, A., Bijnens, L. and Drinkenburg, H.I.M.
(2008). A comparison of doubly hierarchical supervised learning procedures for multiple
class longitudinal data from EEG experiments. Journal of Biopharmaceutical Statistics, 18,
1120-1135.
Speybroeck, N., Marcotty, T., Aerts, M., Dolan, T., Williams, B., Lauer, J., Molenberghs, G.,
Burzykowski, T., Mulumba, M. and Berkvens, D. (2008). Titrating Theileria parva: single
stocks against combination of stocks. International Journal for Parasitology, 118, 522-
530.
Hughes, S., Keene, O., Roes, K., Ashby, D., Beltangadu, M., Bird, S.M., Burton, C., Buyse, M.,
Day, S., van Ewijk, P., Fletcher, C., Grieve, A.P., Guinot, C., Hemmings, R., Hold, D.,
Hothorn, L., Jagers, P., Keiding, N., Korhonen, P., Lesaffre, E., Lewis, J.A., Molenberghs,
G., Neumann, N., Olsen, K.J., van Osta, G., Pocock, S., Rockhold, F., Rossi, A., Senn, S.,
Stijnen, T., Vaeth, M., Wiklund, S.J. and Wolfram, J. (2008). Open Letter to the Heads of
the European Regulatory Agencies. British Medical Journal, 336, 250-250.
Rizopoulos, D., Verbeke, G. and Molenberghs, G. (2008). Shared parameter models under
random-effects misspecification. Biometrika, 95, 63-74.
V
Gyselaers, W., Verswijvel, G., Molenberghs, G. and Ombelet, W. (2008). Interlobar venous
flow is different between left and right kidney in uncomplicated third trimester pregnancy.
Gynecologic and Obstetric Investigation, 65, 6-11.
Van Effelterre, T., Shkedy, Z., Aerts, M., Molenberghs, G., Van Damme, P. and Beutels, P.
(2009). Contact patterns and their implied basic reproductive numbers: an illustration for
varicella-zoster virus. Epidemiology and Infection, 127, 48-57.
Alonso, A., Litière, S. and Molenberghs, G. (2008). A family of tests to detect misspecifications
in the random effects distribution of generalized linear mixed models. Computational
Statistics and Data Analysis, 52, 4474-4486.
Cortiñas, J., Shkedy, Z. and Molenberghs, G. (2008). Alternative methods to evaluate trial
level surrogacy. Clinical Trials, 5, 194-208.
Jacobs, T., Rossenu, S., Dunne, A., Molenberghs, G., Straetemans, R. and Bijnens, L. (2008).
Combined models for data from in vivo-in vitro correlation experiments. Journal of
Biopharmaceutical Statistics, 18, 1197-1211.
Laenen, A., Alonso, A., Molenberghs, G. and Vangeneugden, T. (2008). A family of measures
to evaluate scale reliability in a longitudinal setting. Journal of the Royal Statistical
Society, Series A, 171, 000-000.
Faes, C., Aerts, M., Molenberghs, G., Geys, H., Teuns, G. and Bijnens, L. (2008). A high-
dimensional joint model for longitudinal endpoints of different nature. Statistics in
Medicine, 27, 4408-4427.
Sotto, C., Beunckens, C., Molenberghs, G., Jansen, I. and Verbeke, G. (2008). Marginalizing
pattern-mixture models for categorical data subject to monotone missingness. Metrika,
00, 000-000.
Alonso, A. and Molenberghs, G. (2008). Surrogate markers: Hopes and Perils.
Pharmacoeconomics and Outcomes Research, 8, 255-259.
Gyselaers, W., Molenberghs, G., Van Mieghem, W. and Ombelet, W. (2008). Doppler
measurement of renal interlobar vein impedance index in uncomplicated and pre-
eclamptic pregnancies: a pilot study. Hypertension in Pregnancy, 00, 000-000.
Maringwa, J., Geys, H., Shkedy, Z., Faes, C., Molenberghs, G., Aerts, M., Van Ammel, K.,
Teisman, A. and Bijnens, L. (2008). Tutorial in Biostatistics: Analysis of cross-over
designs with serial correlation within periods using semiparametric mixed models.
Statistics in Medicine, 27, 6009-6033.
Alonso, A., Molenberghs, G., Renard, D. and Darstein, C. (2008). Evaluation of biomarkers for
pharmacological activity. Journal of Biopharmaceutical Statistics, 00, 000-000.
Hill, R.C. Choate, C.J., Scott, K.C. and Molenberghs, G. (2008). Comparison of the guaranteed
analysis with the measured nutrient composition of commercial pet foods. Journal of the
American Veterinary Medical Association, 00, 000-000.
Laenen, A., Alonso, A., Molenberghs, G. and Vangeneugden, T. (2008). Reliability of a
longitudinal sequence of scale ratings. Psychometrika, 00, 000-000. (doi:10:1007/S1136-
008-9079-7)
Jacobs, T., De Ridder, F., Rusch, S., Van Peer, A., Molenberghs, G. and Bijnens, L. (2008).
Including information on the therapeutic window in bioequivalence specifications.
Pharmaceutical Research, 25, 2628-2638.
Decramer, M. and Molenberghs, G. (2008). Letter to the Editor: Does pharmacotherapy
reduce rate of decline of lung function in COPD? American Journal of Respiratory and
Critical Care Medicine, 00, 000-000.
Maringwa, J.T., Faes, C., Geys, H., Molenberghs, G., Cadarso-Suárez, C., Pardo-Vàzquez, J.L.,
Leborán, V. and Acuña, C. (2008). Application of penalized smoothing splines in analyzing
neuronal data. Biometrical Journal, 00, 000--000.
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Molenberghs, G. (2008). Incomplete data in clinical studies: analysis, sensitivity, and
sensitivity analysis (with discussion and rejoinder). Drug Information Journal, 00, 000-
000.
Beunckens, C., Sotto, C., Molenberghs, G. and Verbeke, G. (2008). A multi-faceted sensitivity
analysis of the Slovenian Public Opinion Survey data. Applied Statistics, 00, 000-000.
Laenen, A., Alonso, A., Molenberghs, G., Vangeneugden, T. and Mallinckrodt, C. (2008). Using
longitudinal data from a clinical trial in depression to assess the reliability of its outcome
scale. Journal of Psychiatric Research, 00, 000-000. (doi:10.1016/j.jpsychires.
2008.09.010).
Mwambi, H., Ramroop, S., Shkedy, Z. and Molenberghs, G. (2008). An approach to estimating
the force of infection and the rate of recovery fom Respiratory Syncytial Virus (RSV) data.
Statistical Methods in Medical Research, 00, 000-000.
Goegebeur, Y., De Boeck, P. and Molenberghs, G. (2008). Person fit for test speededness:
Normal curvature, likelihood ratio tests, and empirical Bayes estimates. Methodology, 00,
000-000.
Molenberghs, G., Burzykowski, T., Alonso, A., Assam, P., Tilahun, A. and Buyse, M. (2008). A
unified framework for the evaluation of surrogate endpoints in clinical trials. Statistical
Methods in Medical Research, 00, 000-000.
Serroyen, J., Bruckers, L., Rogiers, G. and Molenberghs, G. (2008). Characterizing persistent
disturbing behavior using longitudinal and multivariate techniques. Journal of Applied
Statistics, 00, 000-000.
Tilahun, A., Maringwa, J.T., Geys, H., Alonso, A., Raeymaekers, L., Molenberghs, G., Van Den
Kieboom, G., Drinkenburg, P. and Bijnens, L. (2009). Investigating association between
behavior, corticosterone, heart rate, and blood pressure in rats using surrogate marker
evaluation methodology. Journal of Biopharmaceutical Statistics, 19, 1-17.
Verbeke, G. and Molenberghs, G. (2009). Arbitrariness of models for augmented and coarse
data, with emphasis on incomplete-data and random-effects models. Statistical Modelling,
00, 000-000.
Beunckens, C., Molenberghs, G., Verbeke, G. and Millinckrodt, C. (2008). A latent-class
mixture model for incomplete longitudinal Gaussian data. Biometrics, 64, 96-105.
Beunckens, C., Sotto, C. and Molenberghs, G. (2008). A simulation study comparing weighted
estimating equations with multiple imputation based estimating equations for longitudinal
binary data. Computational Statistics and Data Analysis. 52, 1533-1548.
Mwambi, K., Ramroop, S., Shkedy, Z. and Molenberghs, G. (2008). A frequentist appraoch to
estimating the force of infection and the recovery rate for respiratory disease among
infants in coastal Kenya. Statistical Methods in Medical Research 000-000.
Gaddah, A. and Braekers, R. (2008). Weak convergence for the conditional distribution
function in a Koziol-Green model under dependent censoring. Journal of Statistical
Planning and Inference (Doi: 10.1016/j.jspi.2008.06.001).
Braekers, R. and Van Keilegom, I. (2008). Flexible modeling base on copulas in
nonparametric median regression. Journal of Multivariate Analysis (Doi:
10.1016/j.jmva.2008.11.2009).
Burzykowski, T., Buyse, M. Yothers, G., Skamoto, J. and Sargent, D. (2008). Exploring and
validating surrogate endpoints in colorectal cancer. Lifetime Data Analysis, 14, 54-64.
Valkenborg, D., Van Sanden, S., Lin, D. , Kasim, A; Zhu, Qi, Haldermans, P., Jansen I.,
Shkedy, Z. and Burzykowski, T. (2008). A cross-validation study to select a classification
procedure for clinical diagnosis base on proteomic mass spectrometry. Statistical
Applications in Genetics and Molecular Biology 7(2), article 12 (available at:
http://www.bepress.com/sagmb/vol7/iss2/art12).
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Van Sanden, S., Lin, D. and Burzykowski, T. (2008). Performance of gene selection and
classification methods in a microarray setting: A simulation study. Communications in
Statistics – Simulation and Computation, 37, 409-424.
Burzykowski, T., Buyse, M., Piccart-Gebhart, MJ., Sledge, G., Carmichael, J., Luck, H-J.,
Mackey J.R., Nabholtz, J-M, Paridaens, R., Biganzoli, L., Jasem, J., Bontenbal, M.,
Bonneterre, J., Chan, S., Atalay Basaran, G. and Therasse, P. (2008). Evaluation of
tumor response, disease control, progression-free survival, and time to progression as
potential surrogate endpoints in metastatic breast cancer. Journal of Clinical Oncology,
26, 1987-1992.
Piccart-Gebhart, M.J., Burzyokowski, T., Buyse, M., Sledge, G., Carmichael, J., Luck, H-J.,
Mackey, J.R., Mabholtz, J-M., Paridaens, R., Biganzoli, L., Jassem, J., Bontenbal, M.
Bonneterre, J., Chan, S., Atalay Basaran G. and Therasse, P. (2008). Effects of taxanes
ablone or in combination with antracyclines as first-line therapy of patients with
metastatic breast cancer. Journal of Clinical Oncology, 26, 1980-1986.
Valkenborg, D., Janssen, I. and Burzykowski, T. (2008). A model-based method for the
prediction of the isotopic distribution of peptides. Journal of the American Society of
Mass Spectrometry, 19, 703-712.
Massonnet, G., Janssen, P. and Burzykowski, T. (2008). Fitting conditional survival models to
meta-analytic data by using a transformation towards mixed-effects models. Biometrics,
64, 8634-842.
Burzykowski, T. (2008). Surrogate endpoints: wishful thinking or reality? Statistical Methods in
Medical Research, 17, 463-466.
Buyse, M., Burzykowski, T., Michiels, S. and Carroll, K. (2008). Individual- and trial-level
surrogacy in colorector cancer. Statistical Methods in Medical Research, 17, 467-475.
Lin, D., Shkedy, Z., Burzykowski, T., Ion, R., Göhlmann, H.W., Bondt, A.D., Perer, T., Geerts,
T., Van den Wyngaert, I. and Bijnens, L. (2008). An investigation on performance of
Significance Analysis of Microarray (SAM) for the comparisions of several treatments with
one control in the presence of small-variance genes. Biometrical Journal, 50, 801-823.
Massonnet, G., Janssen, P. and Burzykowski, T. (2008). Fitting conditional survival models to
meta-analytic data by using a transformation toward mixed-effects models. Biometrics,
64, 834-842.
Hens, N., Aerts, M., Shkedy, Z., Thetten, H., Van Damme, P. and Beutels, P. (2008).
Modelling multi-sera data: the estimation of new joint and conditional epidemiological
parameters. Statistics in Medicine, 27, 2651-2664.
Namata, H., Méroc, E., Aerts, M. , Faes, C., Cortiñas, A.J., Imberechts, H. and Mintiens K.
(2008). Salmonella in Belgian laying hens: An identification of risk factors. Preventive
Veterinary Medicine, 83, 323-336.
Hens, N., Aerts, M., Shkedy, Z., Kimani, P.K., Kojouharova, M., Van Damme, P. and Beutels,
P. (2008). Estimating the impact of vaccination using age-time dependent incidence rates
of Hepatitis B. Epidemiology and Infection, 136, 341-351.
Méroc, E., Faes, C., Herr, C., Verheyden, B., Vanbinst, T., Vandenbussche, F., Hooyberghs, J.
Aerts, M. De Clercq, K., Mintiens, K. and Staubach, C. (2008). Establishing the spread of
bluetongue virus at the end of the 2006 epidemic in Belgium. Veterinary Microbiology,
131, 133-144.
Namata, H., Aerts, M., Faes, C. and Theunis, P. (2008). Model averaging in microbioal risk
assessment using fractional polynomials and generalized linear mixed models. Risk
Analysis, 28, 891-905.
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Theeten, H., Hens, N., Aerts, M., Vandermeulen, C., Roelants, M., Hoppenbrouwers, K., Van
Damme, P. and Beutels, P. (2008). Caregivers’ willingness to pay to reduce the number
of vaccine injections in infants. The Pediatric Infectious Disease Journal, 0, 000-000.
Mintients, K., Méroc, E., Faes, C., Cortiñas Abrahantes, J., Hendrickx, G., Staubach, C.,
Gerbier, G., Elbers, A.R.W., Aerts, M., De Claercq, K. and Deluyker, H. (2008). Impact of
human interventions on the spread of Bluetongue virus serotype 8 during the 2006
epidemic in north-western Europe. Preventive Veterinary Medicine, 87, 145-161.
Cortiñas Abrahantes, J., Bollaerts, K. Aerts, M. Van der Stede, Y., Ogunsanya, V. and Mintiens,
K. (2008). Salmonella serosurveillance: Different statistical methods to categorize pig
herds based in serological data. Preventive Veterinary Medicine 00, 000-000.
Mossong, J., Hens, N., Jit, M., Beutels, P., Auranen, K., Mikolajczyk, R. Massari, M., Scalia
Tomba, G., Wallinga, J., Sadkowska-Todys, Rosinska, M. and Edmunds, J.W. (2008).
Social contacts and mixing patterns relevant to the spread of infectious diseases. PloS
Med 5(3) (e74. doi:10.1371/journal.pmed.0050074).
Hens, N., Aerts, M., Shkedy, Z., Kimani, P.K., Kojouhariva, M., Van Damme, P. and Beutels, P.
(2008). Modeling age-time dependent incidence rates of hepatitis B and estimating the
prevalence and force of infaction using generalized additive models. Epidemiology and
Infection, 136, 341-351.
Mossong, J., Hens, N., Friederichs, V., Davidkin, I., Broman, M., Litwinska, A., Siennicka, J.,
Trzcinska, A., Van Damme, P., Beutels, P., Vyse, A., Shkedy, Z., Aerts, M., Massari, M.
and Gabutti, G. (2008). Epidemiology of parvovirus B19 infection in Europe: results from
a seroprevalence studies in Belgium, England and Wales, Finland, Italy and Poland.
Epidemilogy and Infection, 136, 1059-1068.
Hens, N.,Kvitkovicova, A., Aerts, M., Hlubinka, D. and Beutels, P. (2008). Modelling disortions
in seroprevalence data using change-point fractional polynomials. Statistical Modelling.
(to appear)
Hens, N., Goeyvaerts, N., Aerts, M., Shkedy, Z., Van Damme, P. and Beutels, P. (2008).
Mining social mixing patterns for infectious disease models based on a two-day population
survey in Belgium. (to appear).
Ogunjimi, B., Hens, N., Goeyvaerts, N., Aerts, M. and Beutels, P. (2008). Using empirical
social contact data to model person to person infectious disease transmission: an
illustration for varicella. Mathematical Biosciences. (to appear).
Claeskens, G., Nguti, R. and Janssen, P. (2008) Likelihood ratio and scoretest for a shared
frailty model: a non-standard problem. Test, 17, 69-82.
Goethals, K., Janssen, P. and Duchateau, L. (2008). Frailty models and copulas: Similarities
and differences; Journal of Applied Statistics 35, 1071-1079.
Bollaerts, K., Aerts, M., Ribbens, S., Van der Stede, Y., Boone, I. and Mintiens K. (2008).
Idenficiation of Salmonella high risk pig herds in Belgiumusing semi-parametric quantiles
regression. Journal of the Royal Statistical Society. Series A., 171, 1-16.
Bollaerts, K., Aerts, M., Faes, C., Grijspeerdt, K., Dewulf, J. and Mintiens, K. (2008). Human
Salmonellosis: estimation of dose-illness from outbreak data. Risk Analysis, 28, 427-440.
Delhalle, L., De Sadeleer, L., Bollaerts, K., Farnir, F., Saegerman, C., Korsak, N., Dewulf, J.,
De Zutter, L. and Daube, G. (2008). Risk factors for Salmonella and hygiene indicators in
the 10 largest Belgian pig slaughterhouses. Journal of Food Protection, 71, 1320-1329.
Bollaerts, K., Messens, W., Delhalle, L., Aerts, M., Van der Stede, Y., Dewulf, J., Quoillin, S.,
Maes, D., Mintiens, K. and Grijspreedt, K. (2008) METZOON: Development of a
quantitative microbial risk assessment for human salmonellosis through household
consumption of fresh minced pork meat in Belgium. Risk Analysis (to appear).
NP
Boone, I., Van der Stede, Y., Bollaerts, K., Vose, D., Daube, G., Aerts, M. and Mintiens, K.
(2008). NUSAP method for evaluating the data quality in a quantitative microbial risk
assessment model for Salmonella in the pork production chain. Risk analysis (to appear).
Goethals, K., Ampe, B., Berkvens, D., Laevens, H., Janssen, P. and Duchateau, L. (2008).
Modelling interval-censored, clustered cow udder quarter infection times through the
shared gamma frailty model. Journal of Agricultural, Biological and Ecological Statistics
(to appear).
Legrand, C., Duchateau, L. Janssen, P., Ducrocq, V. and Sylvester, R. (2008/2009). Validation
of prognostic indices using the frailty model. Lifetime Data Analysis (to appear).
Maringwa, J.T., Geys, H., Shkedy, Z., Faes, C., Molenberghs, G., Aerts, M., Van Ammel, K.,
Teisman, A., and Bijnens, L. (2008). Application of semiparametric mixed midels in
simultaneous confidence bands in a cardiovascular safety experiment with longitudinal
data. Journal of Biopharmacuetical Statistics, 18, 1043-1062.
Vyt, P., Maes, D., Quinten, C., Rysselaere, T., Deley, W., Aerts, M., de Kruif A. and Van Soom,
A. (2008). Detailed motility evaluation of boar semen and it predictive value for
reproductive performance in sows. Flemish Veterinary Journal, 77, 291-299.
Faes, C., Geys, H., Aerts, M. and Molenberghs, G. (2008). A flexible method to measure
synchrony in neuronal firing. Journal of the American Statistical Association, 00, 000-
000.
Faes, C., Aerts, M., Geys, H. and De Schaepdrijver, L. (2008). Modeling spatial learning in
rats based on morris water maze experiment. Pharmaceutical Statistics (to appear).
Bilau, M., Matthys, C., Baeyens, W., Bruckers, L., De Backer, G., Den Hond, E., Keune, H.,
Koppen, G., Nelen, V., Schoeters, G., Van Larebeke, N., Willems, J.L. and De Henauw, S.
(2008). Dietary exposure to dioxin-like compounds in three age groups: results from the
Flemish environment and health study. Chemosphere, 70, 584-592.
Schroijen, C., Baeyens, W., Schoeters, G., Den Hond, E., Koppen, G., Bruckers, L., Nelen, V.,
De Mieroop, E., Bilau, M., Covaci, A., Keune, H., Loots, I., Kleinjans, J., Dhooge, W. and
Van Larebeke, N. (2008). Internal exposure to pollutants measured in blood and urine of
Flemish adolescents in function of aera of residence. Chemosphere, 71, 1317-1325.
Abatih, E., Van Oyen, H., Bossuyt, N. and Bruckers, L. (2008). Variance estimation methods
for health expectancy by relative socio-economic status. European Journal of
Epidemiology, 23, 243-249.
Robaeys, G., Nevens, F., Van Eyken, P., Starkel, P., Colle, I., Bruckers, L., Van Ranst, M. and
Buntinx, F. (2008). Intavenous substance use and the outcome if liver transplantation for
chroinc hepatitis C. Journal of Hepatology, 48(Supp.2), 230-…
De Coster, S., Koppen, G., Bracke, M., Schroijen, C., Den Hond, E., Nelen, V., de Mierrrop,
E.V., Bruckers, L., Bilau, M., B aeyens, W., Schoeters, G. and van Larebeke, N. (2008).
Pollutant effects of genotoxic parameters and tumor-associated protein levels in adults: a
cross sectional study. Environmental Health, 7.
Keune, H., Loots, . I., Bruckers, L., Bilau, M. Koppen, G., van Larebeke, N., Schoeters, G. and
Nelen, V. (2008). Monitoring environment, health and perception; an experimental survey
on health and environment in Flanders, Belgium. International Journal of global
environmental issues, 8, 90-111.
Bilau, M., De Henauw, S., Schroijen, C., Bruckers, L., Den Hond, E., Koppen, G., Matthys, C.,
Van de Mieroop, E., Keune, H., Baeyens, W., Nelen; V., Van Larebeke, N., Willems, J.L.
and Schoeters, G. (2009) The relation between the estimated dietary intake of PCDD/Fs)
and levels in blood in a Flemish population (50-65 years). Environment International, 35,
9-13.
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Stracjzek, A., Wannijn, J., Van Hees, M., Thijs, H. and Thiry Y., (2008). Tolerance of hairy
roots of carrots to U-chronic exposure in standardized in vitro device. Environmental and
Experimental Botany (to appear).
Komárek, A. and Lesaffre, E. (2008). Generalized linear mixed model with a penalized
Gaussian mixture as a random-effects distribution. Computation Statistics and Data
Analysis 52, 3441-3458.
Mwalili, S., Lesaffre, E. and Declerck, S. (2008). The zero-inflated negative binomial
regression model dith correction for misclassification: an example in caries research.
Statistical methods in Medical Research, 17, 123-139.
Rizopoulos, D. Verbeke, G., Lesaffre, E. and Vanrenterghem, Y. (2008). A two-part joint
model for the analysis of survival and longitudinal binary data with excess zeros.
Biometrics, 64, 611-619.
Rizopoulos, D., Verbeke, G. and Lesaffre, E. (2008). Fully exponential Laplace approximations
for the joint modelling of survival and longitudinal data. Journal of the Royal Statistical
Association, Series B, in press.
Fieuws, S., Verbeke, G., Maes, B. and Vanrenterghem Y. (2008). Predicting renal graft failure
using multivariate longitudinal profiles. Biostatistics, 9, 419-431.
Ghidey, W., Lesaffre, E. and Verbeke, G. (2008). A comparison of methods for estimating the
random effects distribution of a linear mixed model. Statistical Methods in Medical
Research (in press).
Einmahl, J. and Van Keilegom, I. (2008). Specification tests in nonparametric regression.
Journal of Econometrics, 143, 88-102.
Linton, O., Sperlich, S. and Van Keilegom, I. (2008). Estimation of a semiparametric
transformation model. Annals of Statistics, 36, 686-718.
El Ghouch, A. and Van Keilegom, I. (2008). Nonparametric regression with dependent
censored data. Scandinavian Journal of Statistics, 35, 228-247.
Tas, O., De Rooster, H., Baert, E., Doom, M.H. and Duchateau, L. (2008). The accuracy of the
lactate pro hand-held analyser to determine blood lactate in healthy dogs. Journal of
Small Animals Practice, 49, 504-508.
Catry, D., Duchateau, L. Van De Ven, J. Laevens, H., Opsomer, G., Hasebrouck, F. and De
Kruit, A. (2008). Efficacy of metaphylactic florfenicol therapy during natural outbreaks of
bovine respiratory disease. Journal of Veterinary Pharmacological Therapy, 31, 479-487.
Beijerink, N.J., Bhatti, S.F.M., Okkens, A.C., Dieleman, S.J., Duchateau, L. and Kooistra, H.S.
(2008). Pulsatile plasma profiles of FSH and LH before and during medroxyprogesterone
acetate treatment in the bitch. Theriogenology 70, 179-185.
Buyse, M. and Piedbois, E. (2008) Endpoints and surrogate endpoints in colorectal cancer, a
review of recent developments. Current Opinion Oncol., 20, 466-471.
Baigent, C., Harrell, F., Buyse, M., Emberson, J. and Altman, D. (2008). Ensuring trial validity
by data quality assurance and diversification of monitoring methods. Clinical Trials 5, 49-
55.
Desmedt, C., Haibe-Kains, B., Wirapati, P., Buyse, M., Bontempi, G., Delorenzi, M. Piccart M.
and Sotiriou, C. (2008). Biological processes associated with breast cancer clinical
outcome depend on the molecular subtypes. Clinical Cancer Research, 14, 5158-5165.
Sardari Nia, P., Colpaert, C., Vermeulen, P., Weyler, J., Pezzella, F., Van Schil, P. and Van
Marck, E. (2008). Different growth patterns of non-small cell lung cancer represent
distinct biologic subtypes. Annals of Thorac Surgery, 85(2), 395-405.
Trinh, X.B., Tjalma, W.A., Makar, A.P., Buytaert, G., Weyler, J. and Van Damme, P.A. (2008).
Use of the levonorgestral-releasing intrauterine system in breast cancer patients. Fertil
Steril, 90, 17-22.
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Van Dessel, E., Hubens, G., Ruppert, M., Balliu, L., Weyler, J. and Vaneerdeweg W. (2008).
Roux-en-Y gastric bypass as a re-do procedure for failed restrictive gastric surgery. Surg
Endosc. 22, 1014-1018.
Crop, F., Van Rompaye, B., Paelinck, L., Vakaet, L., Thierens, H. and De Wagter, C. (2008).
On the calibration process of film dosimetry: OLS inverse regression versus WLS inverse
prediction. Physics in Medicine and Biology, 53, 3971-3984.
Overige wetenschappelijke publicaties
25 Overige artikels
Veraverbeke, N. (2008). Conditional residual life under random censorship. In: Advances in
Statistics. Felicitation volume in honour of B.K.Kale. B.C. Armold, U. Gather, S.M. Bendre
(eds). MacMillan India, New Dehli, pp. 174-185.
Molenberghs, G. and Orman, C. (2008). Surrogate endpoints: application in pediatric clinical
trials. In: Concepts and Applications of Pediatric Drug Development Mulberg, A. (ed.)
Ip, E. and Molenberghs, G. (2008). Empirical Bayes. In: International Encyclopedia in
Education.
Sterna, J., Burzykowski, T. (2008). Assessment of the usefulness of the fenestration method
in case of disc extrusion in the cervical and thoraco-lumbar spine in chondrodystrophic
dogs. Polish Journal of Veterinary Sciences, 11, 55-62.
26 Artikels in proceedings
Callaert, H., (2008). Understanding confidence intervals. Proceedings of the Fifth Conference
of the European Society for Research in Mathematics Education. CD-ROM edited by D.
Pantazi and G. Philippou. ISBN 978-9963-671-25-0.
Burzykowski, T., Valkenborg, D. (2008). Processing of high-resolution MALDI-TOF mass
spectrometry data by using an average isotopic distribution. Proceedings of the
Fourteenth National Conference on Application of Mathematics in Biology and Medine.
Warsaw, Poland. Bodnar, M., Forys, U., (eds), 33-38. ISBN 83-903893-4-7.
Bollaerts, K., Messens, W., Delhalle, L., Aerts, M., Dewulf, J., Debusser, E., Boone, I.
Grijspeerdt, K. (2008). Development of a modular quantitative microbial risk assessment
to evaluate zoonotic risks in Belgium: Salmonellosis through consumption of pork as an
example. In Proceedings of 10th European Symposium on Statistical Methods for the Food
Industry, Louvain-la-Neuve, Belgium.
Messens, W., Bollaerts, K., Delhalle, L., Aerts, M., Van der Stede, Y., Quoilin, S., De Busser,
E., Dewulf, J., Maes, D., Boone, I., Mintiens, K.,Grijspeerdt, K. (2008). Development of a
quantitaive microbial risk assessment to evaluate zoonotic risks in belgium: human
salmonellosis through household consumption of minced pork meat. In First Belgian
Symposium on Salmonella Research and Control in Pigs, Ghent Belgium, Book of
proceedings, 43-47. F. Boyens, F. Pasmans (eds) (ISBN 9789058641434).
Bollaerts, K., Aerts, M., Faes, C., Dewulf, J. and Mintiens, K. (2008). Dose-illness models for
human salmonellosis based on outbreak data. In: Proceedings of 23rd International
Workshop on Statistical Modelling. P. Eilers (ed.), Utrecht, the Netherlands, pp.1245-130.
Jacobs, T., Straetemans, R., Rossenu, S., Dunne, A., Molenberghs, G., Bijnens, L. (2008). A
new convolution-based approach to develop a level a in-vitro-in-vivo correlation (IVIVC)
for an extended-release oral dosage form. 2007 Proceedings of the American Statistical
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Association, Biopharmaceutical Section [CD-ROM], Alexandria, VA: American Statistical
Association, p.141-144.
Lin, D., Shkedy, Z., Burykowski, T., Aets, M., Göhlmann, H.W.H., De Bondt, A., Perera, T.,
Geerts, T., Van den Wyngaert, I., Bijnens, L. (2008). Information theory based marker
evaluation 2007 Proceedings of the American Statistical Association, Biopharmaceutical
Section [CD-ROM], Alexandria, VA: American Statistical Association, p.472-479.
Aerts, M., Bollaerts, K., Ribbens, K., Van der Stede, Y., Boone, I. and Mintiens, K. (2008).
Semi-parametric regression to identify farms with high Salmonella infection burden. In:
Proceedings of the 23rd International Workshop on Statistical Modelling, P. Eilers (ed.).
Utrecht, pp.89-92.
Leuridan, E., Hens, N. Ieven, G., Aerts, M., Van Damme, P. (2008). Maternal antibodies
against measles after natural infection or vaccination in parturient women. Proceedings
of the 26th Annual meeting of the European Society for Paediatric Infectious Diseases
ESPID, Graz, Austria, 14-16 May 2008.
Hens, N., Wienke, A., Aerts, M. and Molenberghs, G. (2008). On the correlated frailty model
for bivariate current status data. Proceedings of the workshop on composite likelihood
methods. Warwick, UK, 15-17 April 2008.
Goeyvaerts, N., Hens, N., Ogunjimi, B., Aerts, M., Van Damme, P. and Beutels, P. (2008).
Estimating transmission parameters using social contact data and serological data.
Proceedings of the 24th International Biometric Conference, Dublin, July 13-18, 2008.
Creemers, A., Hens, N., Aerts, M., Molenberghs, G., Verbeke, G., Kenward, M.G. Shared-
parameter models and missingness at random. Proceedings of the 24th International
Biometric Conference, Dublin, July 13-18, 2008. ISBN 978-0-9821919-0-3.
Hens, N., Aerts, M., Melagaro, A., Gay, N., Edmunds, J. Elucidation of the factors producing
any observed differences in the epidemiological patterns of airborne infections across
Europe. Proceedings of the 24th International Biometric Conference, Dublin, July 13-18
2008. ISBN 978-0-9821919-0-3.
Lejeune, O., Hens, N., Bilcke, J. and Beutels, P. Proceedings of the International workshop
facing the challenge of Infectious Diseases – Integrating mathematical modeling,
computational thinking and ICT applications, ISI Foundations, Turin (Italy), October 13-
18, 2008.
Molenberghs, G., Aerts, M., Beunckens, C., Creemers, A., Hens, N., Kenward, M.G., Sotto, C.
and Verbeke, G. Missing not at random models and their missing at random counterparts,
in various modelling frameworks in livro in ACTAS do XVI Congresso da SPE, UTAD – Vila
REAL, 2008.
Hens, N. (2008). Exploiting data for risk evaluation. In: Scientific exploitation of databases
within the framework of food safety risk assessment. Federal Food Safety Authority.
Brussels, Belgium.
Massonnet, G., Janssen, P. and Duchateau, L. (2008). Using copulas to model four-
dimensional udder enfection data. Programme and abstract book 29th Annual conference
of the International Society for Clinical Biostatistcs, Copenhagen, Denmark.
Leanen, A., Alonso, A., Molenberghs, G. and Vangeneugden, T. (2008). Reliability of a
longitudinal sequence of scale ratings. Proceedings of the 24th International Biometric
Conference, Dublin, Ireland. ISBN 978-0-9821919-0-3.
Faes, C., Geys, H. and Catalano, P. (2008). Joint models of discrete and continuous
longitudinal data. In: Handbooks of Modern Statistical Methods: Longitudinal Data
Anlysis. Fitzmaurice, G., Davidian, M., Molenberghs, G. and Verbeke, G. (Eds.) London:
Chapman Hall/CRC, pp.327-348.
NT
Buntinx, F., Aertgeerts, B., Aerts, M., Bruyninckx, R., Knottnerus, J.A., Van den Bruel, A., Van
den Ende, J. (2008). Multivariable analysis in diagnostic accuracy studies. What are the
possiblities? In: The evidence base of clinical diagnosis. J.A. Knottnerus and F. Buntinx
(eds.) John Wiley and Sons (ISBN 1405157879 / 9781405157872), pp. 146-167.
Moons, E., Wets, G. and Aerts, M. (2008). Investigating the Performance if rule-based models
with increasing complexity on the prediction of trip generation and distribution. In:
Frontiers in Brain, Vision and AI. C. Rossi (ed), pp.167-182. ISBN 978-953-7619-04-6
27 Uitgaven van publicaties of proceedings als editor
Fitzmaurice, G., Davidian, M., Molenberghs, G. and Verbeke, G. (2009). Longitudinal Data
Analysis. Handbooks of Modern Statistical Methods. New York: Chapman & Hall/CRC.
Burzykowski, T. Guest editor for Statistical Methods in Medical Research (volume 17, issue 5,
2008)
Duchateau, L. and Janssen, P. (2008). Frailty models. Springer: Statistics for Biology and
Health. ISBN 978-0-387-72834-6.
3 Congressen en voordrachten
31 Organisatie van internationale wetenschappelijke congressen of zomerschool
Tomasz Burzykowski
Cursus ‘Survival Analysis’ georganiseerd door MSOURCE Medical Development and the Polish
Group of the International Society for Clinical Biostatistics, Warsaw, Poland. (17-18 juni 2008)
Censtat
Celebration 20th Anniversary Master in Biostatistics, 10th Anniversary Center for Statistics,
Interuniversity Honorary Doctorate Prof. Normal Breslow, Kick-Off IB2. Universiteit Hasselt.
(10-11 september 2008)
Ziv Shkedy
- One-day Workshop on ‘Dengue in Cuba’. Universiteit Hasselt, 25 april 2008
- One-day Workshop on “HIV/AIDS in developing countries’. Universiteit Hasselt, 27 mei
2008.
- Short course in R and infections diseases. Jimma University, Ethiopia, december 2008.
Workgroup Competing Risks
Seminars on competing Risks
(20/11/2007, 17/1/2008, 19/3/2008, 9/6/2008)
Members: Richard Sylvester and Murielle Maurer (EORTC), Ingrid Van Keilegom, Catherine
Legrand (UCL), Luc Duchateau, Els Goetghebeur, Bart Van Rompaye (UGent), Noël
Veraverbeke, Roel Braekers, Auguste Gaddah, Goele Massonnet, Paul Janssen (UHasselt)
= NU
PO= sççêÇê~ÅÜíÉå=çé=áåíÉêå~íáçå~äÉ=ïÉíÉåëÅÜ~ééÉäáàâÉ=ÅçåÖêÉëëÉå
Noël Veraverbeke
4-8 november 2008. International Seminar on Nonparametric Inference ISNI2008, Vigo,
Spain. Empirical likelihood for non-smooth criterion functions (7 november 2008).
Geert Molenberghs
4-7 maart 2008. 8th German Open Conference on Probability and Statistics, Aachen,
Germany. Every missing not at random model has got a missing at random counterpart with
equal fit (5 maart 2008)
16-19 maart 2008. International Biometric Society Eastern North American Region, Chrystal
City, Virginia. Unified approaches for surrogate marker evaluation from multiple randomized
trials (18 maart 2008)
13-16 april 2008. 2nd Annual FDA/DIA Statistics Forum, Bethesda, Maryland, USA.
Incomplete data in clinical studies: analysis and sensitivity analysis (16 april 2008)
16-17 april 2008. AdvaMed/FDA Statistics Conference on Statistical Issues for Medical
Devices and Diagnostics, Bethesda, Maryland, USA. Incomplete data in clinical studies:
analysis and sensitivity analysis (16 april 2008).
14-17 april 2008. Workshop on Composite Likelihood, University of Warwick, Coventry, UK.
Pseudo-likelihood methodology for marginally, conditionally and hierarchically specified
models (17 april 2008).
6 juni 2008. Johns Hopkins School of Public Health, Baltimore, Maryland, USA. Model
assessment and sensitivity analysis when data are incomplete.
11-13 juni 2008. Graybill Conference VII, Colorado State University, Fort Collins, Colorado,
USA. Eevery missing not at random model has got a missing at random counterpart with
equal fit. (12 juni 2008).
10-11 juli 2008. Epidemiology and Biometry 2008: Recent statistical methods in
epidemiology, Paris, France. Surrogate markers: hopes and perils (10 juli 2008).
13-18 juli 2008. XIV International Biometric Conference, Dublin, Ireland. Publishing in
Biometrics: a journal of the International Biometric Society (14 juli 2008)
13-18 juli 2008. XIV International Biometric Conference, Dublin, Ireland. Every missing not at
random model has got a missing at random coutnerpart with equal fit (14 juli 2008).
13-18 juli 2008. XIV International Biometric Conference, Dublin, Ireland. Recent
developments in longitudinal data analysis (15 juli 2008).
29 juli – 2 augustus 2008. Eleventh Meting of new researchers in statistics and probability.
Institute for Mathematical Statistics. University of Colorado, Boulder, Colorado, USA.
Publishing in Biometrics: a journal of the International Biometric Society (2 augustus 2008).
NV
2-7 augustus 2008. Joint Statistical Meetings, Denver, Colorado, USA. Roundtable discussion
leader on “Is there a future for surrogate marker evaluation in randomized clinical studies” (4
augustus 2008).
23-25 september 2008. Non-clinical statistics conference 2008, Leuven, Belgium. Unified
approaches for surrogate marker evaluation from multiple randomized trials (24 september
2008).
1-4 oktober 2008. Congreso Anual da Sociedade Portuguesa de Estatistica, Villa Real,
Portugal. Every missing not at random model has got a missing at random counterpart with
equal fit (3 oktober 2008).
4-7 november 2008. International Seminar on Nonparametric Inference ISNI 2008, Vigo,
Spain. Every missing not at random model has got a missing at random counterpart with
equal fit (6 november 2008).
10 november 2008. Centraal Bureau voor Statistiek, Voorburg, Nederland. Every missing not
at random model has got a missing at random counterpart with equal fit.
26 november 2008. Hans van Houwelingen Symposium, Leiden, Nederland. Surrogate
markers: hopes and perils.
Roel Braekers
16-19 juni 2008. 22nd Nordic Conference on Mathematical Statistics (NORDSTAT), Vilnius,
Lithuania. A homoscedastic regression model with a copula for the depdency.
Auguste Gaddah
16-19 juni 2008. 22nd Nordic Conference on Mathematical Statistics (NORDSTAT), Vilnius,
Lithuania. An extension of the Koziol-Green model under dependent censoring.
Niel Hens
13-18 juli 2008. 24th International Biometric Conference, Dublin, Ireland. Elucidation of the
factors producing any observed differences in the epidemiological patterns of airborne
infections across Europe.
Cristina Sotto
13-18 juli 2008. 24th International Biometric Conference, Dublin, Ireland. Marginalizing
pattern-mixture models for categorical data subject to monotone missingness.
Annouschka Laenen
13-18 juli 2008. 24th International Biometric Conference, Dublin, Ireland. Reliability of a
longitudinal sequence of scale ratings.
An Ceemers
13-18 juli 2008. 24th International Biometric Conference, Dublin, Ireland. Shared-parameter
models and missingness at random.
= OM
Christel Faes
23-25 september 2008. Non-Clinical Statistics Conference, Leuven. Modeling spatial learning
in rats based on Morris water maze expriments.
Marc Aerts
16-19 maart 2008. International Biometric Society Eastern North American Region, Arlington,
USA. Flexible modelling of age-dependent infectious disease parameters using seroprevalence
data in combination with social contact data.
Caroline Beunckens
12-18 juli 2008. 24th International Biometric Conference, Dublin, Ireland. Stochastic EM
algorithm for incomplete longitudinal data.
Ivy Jansen
12-18 juli 2008. 24th International Biometric Conference, Dublin, Ireland. An algorithm to find
co-regulated gene clusters: important improvements.
12-18 juli 2008. 24th International Biometric Conference, Dublin, Ireland. Pattern-mixture
models for categorical outcomes with non-monotone missingness.
Tomasz Burykowski
19-20 juni 2008. Seventh International Seminar on Statistics in Clinical Practice, Warsaw,
Poland. The use of the isotopic distribution in high-resolution maldi-tof mass spectrometry
data.
16-19 maart 2008. IBS/ENAR2008 Meeting, Arlington Virginia, USA. A model for the analysis
of proteolytic 180 stable-isotope labeled peptides in MALDI-TOF mass spectra.
13-18 juli 2008. XXIVth International Biometrics Conference, Dublin, Ireland. An algorithm to
find co-regulated gene clusters: important improvements.
Kaatje Bollaerts
23-25 januari 2008. 10th European Symposium on Statistical Methods in the Food Industry.
Louvain-la-Neuve. Development of a modular quantitive microbial risk assessment to
evaluate zoonotic risks in Belgium: Salmonellosis through consumption of porc as an example.
7-11 juli 2008. 23rd International Workshop on Statistical Modelling, Utrecht, Nederland.
Dose-illness models for human salmonellosis based on outbreak data.
Tetyana Kadankova
16-19 juli 2008. Second International Conference on Mathematics and Staitstics, Athens,
Greece. A two-sided exit problem for a difference of a compound Poisson process and a
compound renewal process with a discrete phase space (invited talk).
Saskia Litière
13-18 juli 2008. 24th International Biometric Conference, Dublin, Ireland. Diagnostic tools for
misspecification in mixed models.
ON
17-21 augustus 23008. 29th Annual Conference of the International Society for Clinical
Biostatistics, Copenhagen, Denmark. Diagnostic tools for misspecification in mixed models.
Nele Goeyvaerts
12-18 juli 2008. 24th International Biometric Conference, Dublin, Ireland. Estimating infectious
disease parameters from data on social contacts and serological status.
21-25 oktober 2008. DIMACS/ECDC Workshop on spatio temporal and network modeling of
infectious deseases, Tübingen, Germany. Parovirus B19 in five European Countries:
disentagling the sociological and microbiological mechanisms underlying infectious disease
transmission.
Dan Lin
29 juni – 2 juli 2008. First symposium on biopharmaceutical statistics. Shanghai, China.
Selection and evaluation of genomic biomarkers for depression in a microarray setting.
24-28 augustus 2008. 29th International Symposium on Clinical Biostatistics, Copenhagen,
Denmark. Selection and evaluation of genomic biomarkers for depression in a microarray
setting.
Suzy Van Sanden
13-18 juli 2008. International Biometric Conference, Dublin, Ireland. Genomic biomarkers for
a categorical response variable in early drug development microarray experiment.
23-25 september 2008. Non Clinical Statistics Conference, Leuven. Genomic biomarkers for a
binary response in early drug development microarray experiments.
Kasim Adetayo
13-18 juli 2008. International Biometric Conference, Dublin, Ireland. Using baseline gene
expression for multi-compound secreening in early drug development experiments.
23-25 september 2008. Non Clinical Statistics Conference, Leuven. Order restricted
clustering for dose-response microarray experiments.
Kristien Wouters
13-18 juli 2008. International Biometric Conference, Dublin, Ireland. Multivariate functional
linear discriminant analysis based on pairwise pseudo-likelihood modeling combined with
splines.
Tom Jabobs
23-25 september 2008. Non Clinical Statistics Conference, Leuven. Clinical relevance of
dissolution specifications.
Ziv Shkedy
13-18 juli 2008. International Biometric Conference, Dublin, Ireland. Testing procedures on
comparisons of several treatments with one control in a microarray setting.
= OO
Pryseley Assam
13-18 juli 2008. International Biometric Conference, Dublin, Ireland. Using earlier measures
in a longitudinal sequence as a potential surrogate for a later one.
Goele Massonnet
17-21 augustus 2008. 29th Annual Conference of the International Society for Clinical
Biostatistics, Copenhagen, Denmark. Using copulas to model four-dimensional udder infection
data.
Ariel Alonso
13-18 juli 2008. International Biometric Conference, Dublin, Ireland. Random-effects
distribution in generalized linear mixed models: perception and problems.
Harriet Namata
13-18 juli 2008. International Biometric Conference, Dublin, Ireland. Model averaging in
quantitative risk assessment.
33 Voordrachten in het buitenland op uitnodiging van instellingen of organisaties
=Noël Veraverbeke
2-3 april 2008. Charles University, Prague, Czech Republic. Copulas in survival analysis (2
april 2008). =Geert Molenberghs
31 januari – 2 februari 2008. Erasmus Medical Center, Rotterdam, Nederland. Missing values
in clinical research. =21 februari, 27 maart, 24 april 2008. Webinar for Learn Stat, American Statistical Association.
The statistical evaluation of surrogate endpoints in clinical trials (3 sessions of 2 hours)
9-11 april 2008. Erasmus University, NIHES, Rotterdam, Nederland. Longitudinal and
incomplete data.
28-29 april 2008. KULeuven. Numerical techniques for statisticians.
7-9 mei 2008, Graduate Program in Statistics, Neuchatel, Switzerland. Introduction to
longitudinal data analysis.
29 juni 2008. International meeting of the Psychometric Society (IMPS2008), Durham.
Methods for analyzing continuous, discrete and incomplete longitudinal data.
4 augustus 2008. Joint Statistical Meetings, Denver, Colorado, USA. Models for discrete
repeated measurements.
17 augustus 2008. International Society for Clinical Biostatistics, Copenhagen, Denmark
Discrete longitudinal data.
1 september 2008. Conference of the Royal Statistical Society, Nottingham, UK. Models for
discrete repeated measurements.
OP
=7-10 oktober 2008. Congreso Latinoamericano de Sociedades de Estadistica, Montevideo,
Uruguy. Continuous, discrete and incomplete longitudinal data.
13-14 oktober 2008. National University of Cordoba, Argentina. Longitudinal and incomplete
data.
21-22 oktober 2008. Copenhagen, Denmark. Longitudinal and incomplete data.
28 oktober 2008. Royal Statistical Society. Professional Development Center, London, UK.
The statistical evaluation of surrogate endpoints in clinical trials.
17-20 november 2008. ESALQ Course on Models for longitudinal and incomplete data.
ESALQ, Piraciaba, Saõ Paulo, Brasil. Missing values in clinical trials.
Tomasz Burzykowski
7 juli 2008. Department of Statistics, University of Milano Bicocca, Italy. An overview of the
meta-analytic approach to validation of surrogate endpoints in clinical trials.
Marc Aerts
15-17 april 2008. Workshop on composite likelihood methods, Warwick, UK. Pseudo-
likelihood methodology for marginally, conditionally and hierarchically specified models.
22 augustus 2008. Human Sciences Research Council, Pretoria, South Africa. Flexible
modelling of age-dependent infectious disease parameters using seroprevalence data in
combination with social contact data.
23 mei 2008. Instituto de Medicina Tropical ‘Pedro Kouri’ (IPK), La Habana, Cuba. Pseudo-
likelihood methodology for marginally, conditionally and hierarchically specified models.
José Cortiñas
5-6 maart 2008. Meeting of the working Group on the analysis of baseline survey on
Salmonella in Turkeys. Parma, Italië. Statistical considerations for the analysis of survey
data.
Niel Hens
15-17 april 2008. Workshop on composite likelihood methods, Warwick, UK. On the
correlated frailty model for bivariate current status data.
17 januari 2008. Martin-Luther Universität, Halle-Wittenberg. Estimating the association and
heterogeneity in the acquisition of varicella zoster virus and parovirus B19 for five different
European countries.
23 mei 2008. Instituto ‘Pedro Kouri’, Havana, Cuba. Measuring social mixing patterns and
their impact on modelling the spread of airborne infections among humans.
30 juli 2008. University of Washington, USA. Measuring social mixing patterns and their
predictiveness for observed epidemiological patterns.
= OQ
Ziv Shkedy
2 januari 2008. Gertner Institute for Epidemiology and Health Policy Research, Israel.
Identification of genetic biomarkers.
7-8 oktober 2008. European monitoring Center of drug and drug addiction (EMCDDA) expert
meeting on drug related infectious diseases, Lisboa, Portugal. Modeling HVC/HIV: longitudinal
analysis of time series data from Italy.
7-8 oktober 2008. European monitoring Center of drug and drug addiction (EMCDDA) expert
meeting on drug related infectious diseases, Lisboa, Portugal. Modeling subject heterogeneity
from cross-sectional individual data.
5-6 februari 2008. Meeting of the European study Group for mathematical modeling and
epidemiological analysis of drug related infectious diseases, Amsterdam. Modeling the
transition parameters of hepatitis C in injecting drug users.
6-7 november 2008. ESF Workshop, Utrecht. Model averaging for the skyline plot.
Dirk Valkenborg
1 april 2008. Philips Research, Eindhoven. A strategy for the prior preprocessing of high-
resolution mass spectrometry data in the application of peptide-centric proteomics.
Paul Janssen
7-10 mei 2008. Universidad Carlos III, Spain. Contributions to frailty and copula models.
Harriet Namata
23 april 2008. Utrecht, Nederland. Modeling the transmission parameters of Hepatitis C
among injecting drug users.
34 Presentatie van posters op internationale wetenschappelijke congressen
Dan Lin
23-25 september 2008. Non Clinical Statistical Conference, Leuven. Selection and evaluation
of genomic biomarkers for depression in a microarray setting.
Kasim Adetayo
23-25 september 2008. Non Clinical Statistics Conference, Leuven. A latent response
approach to multi-compound screening using baseline gene expression: application to cancer
cell lines.
Tomasz Burzykowski
13-18 juli 2008. 24th International Biometric Conference, Dublin, Ireland. A model for the
analysis of 18O stable-isotope labeled peptides in MALDI-TOF mass spectra.
Marc Aerts
7-11 juli 2008. 23rd International Workshop on Statistical Modelling, Utrecht, NL. Semi-
parametric regression to identify farms with high salmonella infection burden.
OR
Arthur Gitome
23-25 september 2008. Non Clinical Statistics Conference, Leuven. Classification of call lines
based on the response to treatment using PAMSHIPS.
15-17 oktober 2008. 16th Annual Meeting of the Belgian Statistical Society, Wépion-Namur.
Classification of cell lines based on the response to treatment using PAMCHIPS.
Setia Pramana
23-25 september 2008. Non Clinical Statistics Conference, Leuven. Gene expression analysis
in striatum after acute treatment with antipsychotics.
15-17 oktober 2008. 16th Annual Meeting of the Belgian Statistical Society, Wépion-Namur.
Gene expression analysis in striatum after acute treatment with antipsychotics.
Tom Jabobs
23-25 september 2008. Non Clinical Statistics Conference, Leuven. Therapeutic relevance of
bioequivalence acceptance limits.
23-25 september 2008. Non Clinical Statistics Conference, Leuven. An ordinal multinomial
nonlinear model for the effects of investigational compounds on Taxol-induced mechanical
neuropathy.
José Cortiñas
17-21 augustus 2008. 29th Annual Conference of the International Society on Clinical
Biostatistics, Copenhagen, Denmark. Alternative methods to evaluate trial level surrogacy.
25-28 oktober 2008. 48th Annual ICAA/IDSA 46th Annual Meeting, Washington, DC.
Evaluation of chromogenic media for MRSA detection using a combined Bayesian – penalized
likelihood approach.
Harriet Namata
13-18 juli 2008. International Biometric Conference, Dublin, Ireland. Prevalence and
persistence of salmonella in Belgian boiler chicken flocks. An identification of risk factors.
Abel Tilahun
23-25 september 2008. Non Clinical Statistics Conference, Leuven. Measuring associations
using surrogate marker methodology.
13-18 juli 2008. 24th International Biometric Conference, Dublin, Ireland. Investigating
association between CORT heart rate, blood pressure using surrogate marker methodology.
Niel Hens
14-16 mei 2008. 26th Annual Meeting of the European Society for Paediatric Infectious
Diseases – ESPID, Graz, Austria. Maternal antibodies against measles after natural infection
or vaccination in parturient women.
= OS
Dirk Valkenborg
22-26 september 2008. ECCB, Cagliari, Italy. A model-based method estimating the relative
abundance in 18O-labeld mass spectra.
15-16 december 2008. Maastricht, Nederland. Estimating the ion ratio of proteolytic 18O-
isotope labeled peptides.
4 Expert- en referee-opdrachten
41 Lidmaatschappen van editorial board van internationale tijdschriften
Noël Veraverbeke
- Associate editor of South African Statistical Journal (2009- )
- Nationaal correspondent voor International Association for Statistical Education (IASE)
Roel Braekers
- Associate editor ‘Statistica Neerlandica’ (2009- )
Geert Molenberghs
- Wiley Series in Probability and Statistics Editor (Editors: David J. Balding, Noel A.C.
Cressie, Nicholas I. Fisher, Iain M. Johnstone, J.B. Kadane, Geert Molenberghs, Louise M.
Ryan, David W. Scott, Adrian F.M. Smith, Jozef L. Teugels) (2003- )
- Co-editor of Biometrics (2007-2009)
Paul Janssen
- Associate editor “Statistica Neerlandica’ (2003-2008)
Marc Aerts
- Associate editor of Biometrics
- Associate editor of Statistical Modelling: An international journal
Ziv Shkedy
- Associate editor of Biometrics
Tomasz Burzykowski
- Member of editorial board of Advances in Medical Sciences
- Associate editor of Biometrics
42 Referee-opdrachten van publicaties op aanvraag van editorial board van
internationale tijdschriften
Noël Veraverbeke
• Computational Statistics and Data Analysis
• Journal of Statistical Planning and Inference
• Statistics and Probability Letters
• Mathematical Reviews (25)
• Annals of the Institute of Statistical Methematics
• Journal of Nonparametric Statistics
OT
• Journal of the American Statistical Association
• South African Statistical Journal
Geert Molenberghs
• Biometrics (Editor: 230)
• Biostatistics
• Biometrika
• Statistical Science
• Statistics in Medicine
• Journal of the Royal Statistical Society C
• Book Chapter (Springer)
• Book Proposal (Wiley, as advisor, 27)
• Book Proposal (Springer)
Paul Janssen
• Scandinavian Journal of Statistics
• South African Journal of Statistics
Marc Aerts
• Statistics in Medicine
• Communications in Statistics: Simulation and Computation
• Statistica Sinica
• Journal of Applied Statistics
Roel Braekers
• Computational Statistics and Data Analysis
• Computational Statistics
• Journal of Multivariate Analysis
• Annals of the Institute of Statistical Mathematics
• Lifetime Data Analysis
Ariel Alonso
• Statistical Modelling
• Journal of the Royal Statistical Society-Series A
• Biometrics
• Statistics in Medicine
Kaatje Bollaerts
• Risk Analysis
• Statistica Sinica
• Journal of Nonparametric Statistics
Tomasz Burzykowski
• Statistics in Medicine (2)
• STATA Journal (2)
• Biometrics (7)
• Clinical Trials (1)
= OU
Niel Hens
• American Journal of Epidemiology
• Biometrics
• Biometrika
• Statistical Modelling
Goele Massonnet
• International Journal of Biostatistics
• Statistics in Medicine
Christel Faes
• Biometrics (2)
• Journal of Agricultural, Biological and Ecological Statistics (3)
• Biometrical Journal
Herbert Thijs
• Computational Statistics and Data Analysis (4)
Ziv Shkedy
• Statistical Applications in Molecular Biology
• Biometrics
Ivy Jansen
• Annals of Statistics
43 Referee-opdrachten vanprojecten, ingediend bij internationale onderzoeks-
programma’s
Noël Veraverbeke
• Jurylid voor de Belgian American Educational Foundation (BAEF), Alumni Award in Exact
Sciences (2 juni 2008)
• Grant referee for grant Agency of the Academiy of Sciences of the Czech Republic
• Grant referee for the National Research Foundation (NRF) South Africa
Geert Molenberghs
• Faculty member appointment (Denmark: 1)
• Faculty member appointment (Turkey: 1)
• Faculty member promotion (US: 1)
• Panellid by accreditatieaanvraag nieuwe opleiding (NVAO, Nederland: 1)
• Steering committee member of the European Science Foundation Research Networking
Programme on “Quantive Methods in the Social Sciences 2” (QMSS2)
• Grant application (Canada: 1)
• International Statistical Institute (ISF). Life Sciences, Committee Chair (2007-2009)
Marc Aerts
• Scientific expert for the European Food Safety Agency
• Reviewer for FWO-Vlaanderen
OV
Paul Janssen
• Lid van de VLIR werkgroep onderzoek
• Lid van de FWO werkgroep onderzoeksbeleid
• Lid Stuurgroep Onderzoek en Ontwikkeling
• Lid van de Vlaamse Raad voor Wetenschapsbeleid
• UHasselt promotor voor het Steunpunt OOI (lid van de stuurgroep en het dagelijks
bestuur)
• Lid van het Bureau en stuurgroep Universitaire Ontwikkelingssamenwerking
• Vice rector onderzoek (2008-2012)
44 Lidmaatschappen van scientific committee van internationale congressen
Noël Veraverbeke
• AF Math Conference: Actuarial and Financial Mathematics Conference (international
conference), Brussel 5-6 februari 2009. Member of the scientific committee.
• IAP Workshop on Missing Information in Survival Data beyond Right Censoring, Gent, 18-
19 september 2008. Member of the scientific committee.
• 58th ISI Conference, Dublin, 21-27 augustus 2011. Chairman of the General Topics
Committee
• International Seminar on Nonparametric Inference ISNI2008, Vigo, Spain. Member of the
scientific committee
Geert Molenberghs
• XXX Conference of the International Society for Clinical Biostatistics, ISCB30, Prague,
Czech Republic, 23-27 augustus 2009. Chair of the Scientific Program Committee
• International Seminar on Nonparametric Inference, ISNI2008, Vigo, Spain, Member of the
scientific committee
Paul Janssen
• IAP Worshop on Missing Inforamtion in Survival Data beyond Right Censoring, Gent, 18-19
september 2008. Member of the scientific committee and local co-organizer.
Ziv Shkedy
• NSC2008: Statistical Methods for Pharmaceutical Research and Early Development,
Leuven, 23-25 september 2008. Member of the organising committee
45 Referee-opdrachten t.a.v. internationale congressen
/
46 Lidmaatschappen van wetenschappelijke commissies in binnen- en buitenland
Noël Veraverbeke
• Lid van de Hoge Raad voor Statistiek (benoemd op 8 november 1998)
• Lid van het Wetenschappelijk Comité van de enquête 2001 (2001- )
• Lid van de Scientific Council van Eurandom, Eindhoven, Nederland (2004-2010)
• Lid van de stuurgroep van de FWO Wetenschappelijke Onderzoeksgemeenschap Wiskunde
(1996- )
• Lid van de jury van de Vlaamse Wiskunde Olympiade (1985- ) Voorzitter (2007- )
= PM
• Vertegenwoordiger van FWO-Vlaanderen in de vergaderingen van Mathematics
Representatives of the European Union (Paris 2003, Stockholm 2004, Berlin 2005, London
2006, Oslo 2007, Valencia 2008)
• Jurylid Prijs Ontwikkelingssamenwerking (2005- )
• Verantwoordelijke voor het Outreach Programme van de Bernoulli Society (2005- )
• Lid van de VLIR werkgroep Internationalisering (2006- )
Geert Molenberghs
• Lid van de Wetenschappelijke Commissie Wiskunde van het FWO (2003-2009)
• Lid van de Commissie voor International Wetenschappelijke Contacten van het FWO (2003-
2009)
Ziv Shkedy
• President of the Three County Corner Club of the Royal Statistical Society
Paul Janssen
• President van de Belgische Vereniging voor Statistiek
Herbert Thijs
• Independent Data Monitoring Committee for Sanofi Aventis (2008-2009)
• Independent Data Monitoring Committee for J&JPRD (2008-2009)
5 Verwerving van extern gefinancierde onderzoeksprojecten
51 Verwerving van onderzoeksprojecten als projectleider met internationale
participatie
Geert Molenberghs
VLIR Eigen Initiatief Cuba: Biostatistics and Bioinformatics Education and Research (2006-
2010)
Marc Aerts
Project leader “Biostatistics and Modelling”, IUC VLIR Partner Programme, Mondlane
University, Mozambique (UEM)
Paul Janssen
Project leader “Epidemiology and Modelling of Infectious Diseases”, IUC VLIR Partner
Programme, Jimma University, Jimma, Ethiopia.
Ziv Shkedy
Project Leader VLIR-UOS North-South-South Cooperation Programme.
PN
52 Verwerving van onderzoeksprojecten als deelnemer met internationale
participatie
Noël Veraverbeke
Spanish Ministry of Education
Title: Flexible statistical inference: methodological advances and new applications in
engineering, economics, and biomedical sciences (FSI-EEB) (2008-2011). Reference MTM
2008-03129.
Principal investigator: Jacobo de Uña Alvarez, University of Vigo, Spain
Co-investigator: Noël Veraverbeke
Niel Hens
Methusalem grant Vaxinfectio (UAntwerpen) and Censtat (UHasselt)
Christel Faes
• EPIZONE “Epidemiology and surveillance of bluetongue virus serotype 8 in Europe” (1 year
– for networking) Promotor: Koens Mintiens
• EFSA “Request for assistance in statistical analysis of the 2008 EU-wide baseline surveys on
broiler flocks and broiler carcasses”
• Project title: Generalized additive modelling in studies of association, prediction, and
classification. Applications in medicine and biology. Reference MTM2008-01603. Financed
by the Spanish Ministry of Science for the period 2008-2011.
53 Verwerving van binnenlandse (nationaal of regionaal) onderzoeksprojecten
Christel Faes
FWO Nieuw onderzoeksproject “A flexible method for modelling non-normal hierarchical data
structures (promotor: Geert Molenberghs; co-promotor: Christel Faes)
Herbert Thijs
UHasselt IOF Grant
Marc Aerts
Co-promotor of the SBO-IWT (Strategisch Basisonderzoek) grant “Simulation models of
infectious disease transmission and control processes (SIMID), with applications to five major
health policy issues in Flanders, “January 1, 2007 – December 31, 2010.
Geert Molenberghs
Censtat dienstverlening: In 2008 werd met volgende instellingen/bedrijven samengewerkt:
Amsterdam Molecular Therapeutics (AMT), Belgian Association for Cardio-Thoracic Surgery
(BACTS), Boehringer Ingelheim GmbH, Bristol-Myers Squibb International Corporation,
Caridian BCT Europe, Centraal Bureau voor de Statistiek van Nederland (CBS), Centrum voor
Alcohol- en andere drugproblemen (CAD), Centrum voor Huisartsgeneeskunde (UA), CODA-
CERVA, Eli Lilly, European Academy for Gynecological Surgery vzw, European Food Safety
Authority (EFSA), Federale Diensten voor Wetenschappelijke, Technische en Culturele
aangelegenheden (DWTC), IM Associates, International Drug Development Institute (IDDI),
Janssen Pharmaceutica NV, Johnson & Johnson Pharmaceutical Research and Development
L.L.C., KULeuven, LOOA (Limburgs Overleg Onderwijs Arbeid), Mars Belgium, Mars UK
Limited, NYCOMED Belgium, Openbare Vlaamse afvalstoffen Maatschappij (OVAM), Pierre
= PO
Fabra Médicament, Provinciale Hogeschool Limurg (PHL), Provincie Limburg, Rekenhof, Sanofi-
Aventis Recherche & Développement, Schwarz Biosciences, Tibotec bvba, UCB Pharma sa,
Universitair Ziekenhuis Maastricht, Virga Jesse Ziekenhuis, Vlaams Agentschap Zorg en
Gezondheid, Vlaams Instituut voor Technologisch Onderzoek (VITO), Vlaamse
Interuniversitaire Raad (VLIR), Vrije Universiteit Brussel (VUB), Ziekenhuis Oost-Limburg
(ZOL)
6 Prijzen, vermeldingen, gerealiseerde toepassingen
61 Behaalde wetenschappelijke prijzen
Geert Molenberghs
2009 Excellence in Continuing Education Award of the American Statistical Association for
Course on Discrete Londigitudinal Data, presented by Verbeke, G. and Molenberghs, G.
at the Joint Statistical Meetings, Denver, Colorado (04/08/2008). Awarded at the
Joint Statistical meetings in Washintgon, District of Columbia, XX/08/2009.
2008-2009: Belgian Francqui Chair, Universiteit Antwerpen.
Dan Lin
Quetelet prize for the best master thesis biostatistics, UH, 2007
Kaatje Bollaerts
Prize of the best International Workshop on Statistical Modelling 2008 Student presentation
7 Samenwerking met andere wetenschappelijke instellingen en onderzoekers
72 Verblijf van buitenlandse onderzoekers aan de UHasselt
Jeanine Houwing-Duistermaat, Universiteit Leiden, Nederland
1 december 2009 – 9 januari 2008; genetic epidemiology; onderwijs
Financiering: UHasselt
Lizet Sánchez Valdés, Tropical Institute ‘Pedro Kouri’, Havana, Cuba
17 maart – 31 mei 2008; infectious diseases; onderzoek
Financiering: VLIR - Cuba
Fasil Tessema, Jimma University, Ethiopia
1 februari – 31 maart 2008; onderzoek
Financiering: VLIR – Jimma
Yehenew Getachew, Jimma University, Ettiopia
1 februari – 31 maart 2008; onderzoek survival analysis
Financiering: VLIR – Jimma
Wondwossem Kassahun, Jimma University, Ethiopia
1 februari – 31 maart 2008; onderzoek
Financiering: VLIR – Jimma
Clarice Demétrio, Sao Paulo State Unviersity, Brasil
1 mei – 30 juni 2008; biometry; onderwijs en onderzoek
Financiering: VLIR
PP
Marek Omelka, Charles University, Prague, Czech Republic
15 april – 14 oktober 2008; copulas; onderzoek
Financiering;: IUAP project
Afriano Marcio Correia Vieira, University of Brasilia
1 maart – 30 september 2008; onderzoek
Financiering: eigen financiering
Dani Yekutieli, Tel Aviv University, Israel
27-29 maart 2008; Bayesian inference; onderzoek
Financiering: UHasselt
Liset Oropesa Gonzalez, Tropical Institute ‘Pedro Kouri’, Havana, Cuba
25 april 2008; infections diseases; onderzoek
Financiering: UHasselt
Dimitris Karlis, Athens University, Greece
18 april 2008; missing data; onderzoek
Financiering: UHasselt
Khangelani Zuma, Human Sciences Research Council, Pretoria, South Africa
22 mei – 1 juni 2008; HiV research; onderzoek
Financiering: UHasselt
Marta Fiocco, Leiden University, Nederland
19 juni 2008; onderzoek composite likelihood
Financiering: UHasselt
Hector de Arazoa, University of Habana, Cuba
12 juni 2008; HiV research; onderzoek
Financiering; UHasselt
Bennet Kato, King’s Collega, London, UK
8-12 augustus 2008; microarray data; onderzoek
Financiering: UHasselt
Ricardo Cao, University of La Coruna, Spain
7-11 september 2008; survival analysis; onderzoek
Financiering: IUAP project
Andreas Wienke, Universität Halle – Wittenberg, Germany
7-9 september 2008; frailty models; onderzoek
Financiering: UHasselt
James Steven Marron, University of North Carolina, Chapel Hill, USA
8-11 september 2008; object oriented data analysis; onderzoek
Financiering: UHasselt
Norman Breslow, University of Washington, Seattle, USA
8-13 september 2008; Wilms Tumor Study; onderzoek
Financiering: UHasselt
Dhammika Amaratunga, Johnson and Johnson Pharmaceutical Research and Development,
Raritan, New Jersey, USA
9-13 september 2008; classification methods; onderzoek
Financiering: UHasselt
Michal Kulich, Charles University, Prague, Czech Republic
9-12 september 2008; regression; onderzoek
Financiering: UHasselt
Dimitris Rizopoulos, Universiteit Rotterdam, Nederland
10-11 september 2008; Laplace approximation; onderzoek
Financiering: UHasselt
= PQ
Jelle Goeman, Universiteit Leiden, Nederland
10 september 2008; onderzoek
Financiering: UHasselt
Dan Kajungu, Uganda Malaria Surveillance Project, Kampala, Uganda
15-28 september 2008 ; infectious diseases ; onderzoek
Financiering : IUAP Project
Bart Mertens, University Leiden, Nederland
12 september 2008 ; onderzoek
Financiering: UHasselt
Carmen Cadarso Suarez, Unviersity of Santiago de Compostela, Spain
26 september 2008; onderzoek
Financiering: UHasselt
Anastasios Tsiatis, North Carolina State University, Raleigh, USA
26 september 2008; onderzoek
Financiering: UHasselt
Marie Davidian, North Carolina State University, Raleigh, USA
26 september 2008; onderzoek
Financiering: UHasselt
Garret Fitzmaurice, Harvard School of Public Health, Boston, USA
12-14 december 2008; longitudinal data; onderzroek
Financiering: UHasselt
Yehenew Getachew, Jimma Univeristy, Ethiopia
1 september – 31 december 2008; onderzoek
Financiering: VLIR – Jimma
73 Gemeenschappelijk verricht onderzoek
Jan Swanepoel (North-West University, Potchefstroom, Zuid Afrika)
Paul Janssen en Noël Veraverbeke
Resampling, modified bootstrap and goodness-of-fit
Bilateral Scientific and Technological Cooperation
21-30 januari 2008: P. Janssen en N. Veraverbeke in Potchefstroom
BOF bilaterale samenwerking
Stéphane Loisel (Université de Lyon 1, France) and Claudio Macci (University of Rome, Tor
Vergata)
Noël Veraverbeke
Risk Theory
Individueel akkoord
13-15 februari 2008: Noël Veraverbeke in Lyon
Ingrid Van Keilegom (UCL)
Noël Veraverbeke
Empirical likelihood with non smooth criterion function
Individueel akkoord
Ingrid Van Keilegom (UCL)
Roel Braekers
Copulas in regression
Individueel akkoord
PR
Elisa Molanes (University Carlos III Madrid, Spain)
Noël Veraverbeke
Empirical likelihood
Individueel akkoord
Irène Gijbels (KULeuven) en Marek Omelka (Charles University, Prague)
Noël Veraverbeke
Copula estimation
IAP Network
15 april – 14 otober 2008: Marek Omelka in UHasselt
Paul Markel (Minot State University, USA)
Roel Braekers
Zero inflated Cox regression model for left-censored data
Individueel akkoord
Ricardo Cao and Ignacio Lopez de Ullibarri (University of La Coruña, Spain)
Paul Janssen
Frailty models
Individueel akkoord
Luc Ducateau (UGent)
Paul Janssen, Goele Massonnet
Frailty models
Individueel akkoord
Jimma University, Jimma, Ethiopia
Paul Janssen, Noël Veraverbeke, Ziv Shkedy
IUS samenwerking
8-14 december 2008: Paul Janssen en Ziv Shkedy in Jimma
VLIR-UOS
Pierre Van Damme, Philippe Beutels, Heidi Theeten, Koen Van Herck, Elke Leuridan, Gaelle
Boulet, John-Paul Bogers, Kris Vestreken, Joke Bilcke, Oliver Lejeune, Benson Ongunjimi
(UA), Koen Mintiens, Stefan Roels, Yves Vanderstede, Estelle Méroc (Centrum voor
Onderzoek in Diergeneeskunde en Agrochemie), Dirk Berkvens, Nico Speybroeck
(Instituut voor Tropische Geneeskunde), Patrick Cras (UA), Claude Saegerman (Un
Liège), Peter Teunis en Jaco Wallinga (RIVM, Bilthoven, NL)
Marc Aerts, Ziv Shkedy, Geert Molenberghs, Christel Faes, Niel Hens, José Cortiñas,
Kaatje Bollaerts, Harriet Namata, Nele Goevaerts, Yovanna Amparo Castro Sanchez
Modelling infectious diseases
FWO, Polymod, SBOSIMID
Methusalem Project on Vaccine and Infectious diseases (UH and UA): Herman Goossens, Greet
Ieven, Vanessa Vankerckhoven, Katherine Loens
Patrick Cras, Bart Van Everbroeck, Pierre Van Damme, Philippe Beutels, Koen Van Herck
(Universiteit Antwerpen), Dirk Berkvens (Instituut voor Tropische Geneeskunde), Claude
Saegerman (Universiteit Luik), Koen Mintiens, Stefan Roels (Centrum voor Onderzoek in
de Diergeneeskunde en Agrochemie).
Marc Aerts
FWO
= PS
Koen Mintiens, Ides Boone, Yves Van der Stede (Centrum voor Onderzoek in de
Diergeneeskunde en Agrochemie), Georges Daubes, Laurent Delhalle (Universiteit Luik),
Jeroen Dewulf, Dominiek Maes (Universiteit Gent), Koen Grijspeerdt (Instituut voor
Landbouw- en Visserijonderzoek)
Marc Aerts
Project FOD Volksgezondheid
Frank Buntinx, Ann Van der Bruel (KULeuven)
Marc Aerts
Europees project POLYMOD: Pierre Van Damme, Philippe Beutels (Universiteit Antwerpen),
Peter Teunis, Jacco Wallinga (RIVM) + 14 European partner research institutes
Marc Aerts
Europees project Polymod
Jeffrey Simonoff (New York University, USA)
Marc Aerts, Niel Hens
Model selection
Individueel akkoord
Mike Kenward (London School of Hygiene and Tropical Medicine, UK)
Marc Aerts, Geert Molenberghs, Herbert Thijs, Niel Hens, Ivy Janssen, An Creemers
Incomplete clinical trial data
IAP Network and ESRC Grant
Diverse bezoeken
Marc Van Ranst, Pieter Maes (KULeuven), Ignace Glorieux (VUB) Niel Hens, Marc Aerts,
Christel Faes
Modelling pandemic influenza : the impact on Flanders
Individueel akkoord
Kristel Van Steen, Els Goetghebeur, Stijn Vansteelandt (UGent), Mike Kenward (London),
Dimitris Rizopoulos, Sypridoula Tsonoka, Geert Verbeke (KULeuven)
Geert Molenberghs, Marc Aerts, Herbert Thijs, Ivy Janssen, Caroline Beunckens, An
Creemers, Cristina Sotto
Missing data and sensitivity analysis
Individueel akkoord
Didier Renard (Novartis), Tony Vangeneugden, Geert Molenberghs, Tomasz Burzykowski,
Helena Geys, José Cortiñas, Ariel Alonso, Ziv Shkedy, Abel Tilahun, Pryseley Assam
Surrogate markers
Individueel akkoord
Paul Eilers (Universiteit Utrecht, Nederland)
Kaatje Bollaerts, Marc Aerts, Niel Hens
Splines
15-19 december: NH in Utrecht
Universiteit Utrecht
John Edmunds and Nigel Gay, Alessia Melagro (Health Protection Agency, London, UK)
Niel Hens, Nele Goeyvaerts
Elucidation on differences in the sero-epidemiology of VZV and B19 in five European
Countries
Polymod project
PT
Geert Verbeke, Iven Van Mechelen, Francis Tuerlinckx, Paul De Boeck, Dirk Smits (KULeuven)
Geert Molenberghs
Logistic models in item response theory
Individueel akkoord
Michael Kenward (London), Raymond Caroll (Texas A&M University), Craig Malinckrodt (Eli
Lilly, Indianapolis, USA)
Geert Molenberghs, Caroline Beunckens, Ivy Jansen, Cristina Sotto
Missing data in clinical trials
Individueel akkoord
Carmen Cadarso Suarez (Santiago de Compostela, Spain)
Geert Molenberghs, Helena Geys, Ariel Alonso, Christel Faes
Neuro synchronization
Grant BMF2005-00818 (Spain)
Peter Boyen, Frank Neven (Infolab, UHasselt)
Ivy Jansen
Protein-protein interaction networks
Individueel akkoord
P. Manfredi (Pisa), G. Scalia Tomba (Rome), Mirjam Kretzschmar (Utrecht), Peter Theunis
(Bilthoven), Emanuele del Fava, Ziv Shkedy
Infectious deseases
Individueel akkoord
University of Michigan (Ann Arbor, Michigan, USA)
Tomasz Burzykowski
FWO
9-16 augustus 2008: TB in Ann Arbor
Gail Potter en Ira Longini (University of Washinton)
Niel Hens
Egocentric data
21 juli – 21 augustus: Niel Hens in Washington
Individueel akkoord
Jacco Wallinga (Utrecht), Teel Tamme (formerly UHasselt)
Niel Hens, Ziv Shkedy
Epidemic trees
Individueel akkoord
Didier Renard (Vovartis, Belgium), Christelle Darstein (Eli Lilly, USA)
Ariel Alonso, Saskia Litière, Annouschka Laenen, Geert Molenberghs
Biomarkers
Individueel akkoord
Luc Bijnens (Janssen Pharma), Luc Wouters (Barrier Therapeutics)
Dan Lin
Microarray data
Individueel akkoord
Individueel akkoord
George Daube (UL), Lieven De Zutter (UG), Koen Grijspeerdt (CLO), Koen Mintiens (CODA),
Herman Van Oyen (WIV)
Kaatje Bollaerts, Marc Aerts, Ziv Shkedy
Individueel akkoord
Koen Kras (Pronota)
= PU
Dirk Valkenborg, Tomasz Burzykowski
Microarray data
Individueel akkoord
Dani Yekutieli, (Tel-Aviv University, Israel)
Dan Lin, Tomasz Burzykowski, Ziv Shkedy
Microarray experiments
Individueel akkoord
Roel Straetemans (Janssen Pharma) en A. Dunne (University College, Dublin)
Tom Jacobs, Geert Molenberghs
Mixed effects modeling
Individueel akkoord
University of Havana, Cuba
Geert Molenberghs, José Cortiñas, Niel Hens
Training and Research program in medical statistics and bioinformatics
20-30 juni 2008: José Cortinas in Cuba
19-29 mei 2008: Niel Hens in Cuba
VLIR-UOS
Edward Ip (Wake Forest Univeristy, Winston-Salem, USA)
Geert Molenberghs
Logistic models in item response theory
Individueel akkoord
Yuri Goegebeur (University of Southern Denmark, Odense)
Geert Molenberghs
Item response theory
Individueel akkoord
Clarice Demétrio en Afriano Vieira (Sao Paulo State University, Brasil)
Geert Molenberghs, Tony Vangeneugden, Geert Verbeke
Combined longitudinal-overdispersed models
Individueel akkoord
Andreas Wienke (Martin-Luther Universität Halle-Wittenberg)
Niel Hens, Marc Aerts, Geert Molenberghs
Current status data
16-17 januari: NH in Halle-Wittenberg
Individueel akkoord
Janne Lehtiö (Karolinska Institutet, Stockholm)
Tomasz Burzykowski, Dirk Valkenborg
Bioinformatics: Mass-spectrometry data
Individueel akkoord
Andrea Kvitkovicova, Daniel Hlubinka (Charles University, Prague)
Niel hens, Marc Aerts Modelling seroprevalence data
Individueel akkoord
Koen Matthijs (KULeuven) en Bart Van de Putte (UGent)
Christel Faes
Historische demografie
FWO-WOG
PV
Peter Ekamper en Frans van Poppel (Netherlands Interdisciplinary Demographic Institute)
Christel Faes
Historische demografie
FWO-WOG
Koen Mintiens (Vose Consulting Belgium), Yves Van der Stede (VAR Belgium), Estalle Méroc
(VAR, belgium), Armin Elbers (CVI, the Netherlands), Alinde de Koeijer (CVI, the
Nederlands), Christoph Staubach (FLI, Germany), Franz Conraths (FLI, Germany), Helène
Guis (CIRAD, France)
Christel Faes
Spatio-temporal spead of infectious diseases
EPIZONE
27-28 oktober 2008: Christel Faes in Berlin (EPIZONE meeting)
Estelle Méroc, Yves van der Stede and Koen Mintiens (Veterinary and Agrochemical Research
Centre, Belgium)
Christel Faes
Bluetongue infection
Consulting en FWO
Wim Talloen, Anne De Bondt, Hinrich Goehlmann, Luc Bijnens (Janssen Pharmaceutica)
Arthur Gitome, Setia Pramana, Suzy Van Sanden, Ziv Shkedy, Dan Lin, Adetayo Kassim
Microarrays
Individueel akkoord
Dhammika Amaratunga (Johnson & Johnson, Raritan, New Jersey, USA)
Philippe Haldermans
Microarray analysis
Individueel akkoord
11-22 augustus 2008: Philippe Haldermans in Raritan
= QM
Activiteitenverslag - Voordrachten op nationale of regionale congressen, studiedagen, symposia,
workshops Herman Callaert - 8-15-22 oktober 2008. Vliebergh-Sencie, Leuven. Nascholing voor leerkrachten
wiskunde van het secundair onderwijs (derde graad). Kansmodellen en betrouwbaarheidsintervallen.
- 12-19-26 november 2008. CNO, UAntwerpen. Nascholing voor leerkrachten wiskunde van het secundair onderwijs (derde graad). Kansmodellen en betrouwbaarheids- intervallen.
Noël Veraverbeke - 16 mei 2008. Université catholique de Louvain. Copulas in survival models. - 31 oktober 2008. Katholieke Universiteit Leuven. Coloquiumvoordracht. Half a
century of Kaplan-Meier estimation in survival analysis (1958-2008). Geert Molenberghs - 22 maart 2008. UHasselt. Pseudo-likelihood methodology for marginally, conditionally
and hierarchically specified models. - 22 mei 2008. UHasselt. Incomplete data in clinical studies: analysis and sensitivity
analysis. - 4 september 2008. UAntwerpen. Clinical trials and surrogate markers. - 4 september 2008. UAntwerpen. Closing remarks First Joint Scientific Meeting –
Methusalem Consortium. - 30 september 2008. KULeuven. Medical Statistics and Epidemiology. - 23 oktober 2008. Paneldiscussie. Research Careers “Kennismakers” Symposium for
the 80th Anniversary FWO Vlaanderen, Brussel. - 9 december 2008. UAntwerpen. Statistical methods in (pre)clinical trials. Roel Braekers - 9 juni 2008. Universiteit Gent. Overview dependent censoring. Auguste Gaddah - 18-19 september 2008. UGent. IAP Workshop Missing information in survival analysis
beyond right censoring. An extension of the Koziol-Green model under dependent censoring.
José Cortiñas - 18-19 september 2008. UGent. IAP Workshop Missing information in survival analysis
beyond right censoring. Modelling strategies for surrogate validation for multivariate failure time data.
- 4 september 2008. First Joint Scientific Meeting – Methusalem Consortium: Vaccine and Infectious Disease Institute (Vaxinfectio), UA and UH, UHasselt Statistical tools to evaluate diagnostic tests in medical microbiology.
QN
Niel Hens - 18-20 september 2008. UGent. IAP Workshop Missing information in survival analysis
beyond right censoring. A simulation – based assessment of the correlated frailty model for bivariate current status data.
- 16-17 oktober 2008. 16th Annual Meeting of the Belgian Statistical Society, Wépion-Namur. Identifying missing links in pneumonic plague epidemics using a prior-based EM algorithm.
Ivy Jansen - 3 november 2008. Leuven. Statistics Seminar. Identifying overlapping peptides in
mass spectra. Marc Aerts - 12 december 2008. Workshop on Infectious Disease Epidemiology for Decision Making
– Belgian Association of Public Health, Brussel. Seroprevalence studies as methods for public health decisions.
- 4 september 2008. First Joint Scientific Meeting Methusalem Consortium, Antwerpen. Ten years of collaboration on estimating infectious disease parameters for simulation models.
- 9 juni 2008. Workshop on estimating contact patterns and their implications for infectious disease modelling. POLYMOD Final Meeting, Antwerpen. Estimating the force of infection directly from antibody levels.
Christel faes - 15-17 oktober 2008. 16th Annual Meeting of the Belgian Statistical Society, Wépion-
Namur. Young Statisticians Afternoon. Joint models for continuous and discrete longitudinal data.
- 15-17 oktober 2008. 16th Annual Meeting of the Belgian Statistical Society, Wépion-Namur. A high-dimensional joint model for longitudinal endpoints of different type.
- 4 december 2008. Gent. Dag van de historische demografie (WOG). Tijd- en ruimteeffecten in de afstand tussen huwelijkspartners.
Nele Goeyvaerts - 9 juni 2008. UAntwerpen. Estimating transmission parameters using social contact
data and serological data on the varicella zoster virus in Belgium. Suzy Van Sanden - 20 juni 2008. UHasselt. Genomic biomarkers for a binary clinical outcome in early
drug development microarray experiments. Adetayo Kasim - 13 oktober 2008. Janssen Pharmaceutica, Beerse. Order restricted clustering for
dose-response microarray experiments. Qi Zhu - 15 februari 2008. BSMS. BBC Conference Identifiability of 16O-18O labeled mass
spectra: a simulation study (poster) - 17 otkober 2008. 16th Annual Meeting of the Belgian Statistical Society, Wépion-
Namur. A Bayesian approach to identify overlapping peptides in a mass spectrum.
= QO
Arthur Gitome - 15-17 oktober 2008. 16th Annual Meeting of the Belgian Statistical Society, Wépion-
Namur. Classification of cell lines based on the response to treatment using PAMCHIPS.
Setia Pramana - 15-17 oktober 2008. 16th Annual Meeting of the Belgian Statistical Society, Wépion-
Namur. Testing for trend in dose-response microarray experiments. Cristina Sotto - 10-11 september 2008. Censtat Anniversary Celebration, UHasselt. MCMC-based
estimation methods for continuous longitudinal data with monotone and non-monotone missingness.
- 18-20 september 2008. IAP Workshop Missing Information in survival data beyond right censoring, UGent. A simulation study comparing weighted estimating equations and multiple imputation based estimating equations for longitudinal binary data.
Goele Massonnet - 13 juni 2008. Seminars in Statistics. UHasselt. Using copulas to model multivariate
survival data. - 2 oktober 2008. Statistics Seminar. KULeuven. Contributions to frailty and copula
modelling with applications to clinical trials and dairy cows data. - 14 november 2008. Statistics Seminar UCL. Louvain-la-Neuve. Contributions to
frailty and copula modelling with applications to clinical trials and dairy cows data.
= QP
Congressen (passieve deelname) Herman Callaert - National Council of Teachers of Mathematics Conference. Salt Lake City and Oklahoma
City. Noël Veraverbeke - Symposium 10 years Eurandom ‘A random tour through a decade of research.
Eindhoven, 26-28 augustus 2008. - IAP Workshop Missing information in survival data beyond right censoring. UGent, 18-
19 september 2008. - 16th Annual Meeting of the Belgian Statistical Society. Wépion-Namur, 16-17 oktober
2008. - International Workshop FMSR 2008, Flexible Modelling: smoothing and robustness.
KULeuven, 12-14 november 2008. - Bijeenkomst Stochastici. Lunteren, Nederland, 17-19 november 2008. Kaatje Bollaerts - International Workshop FMSR 2008. Flexible Modelling: smoothing and robustness.
KULeuven, 12-14 november 2008. Roel Braekers - IAP Workshop Missing information in survival analysis beyond right censoring. UGent,
18-19 september 2008. Qi Zhu - 3rd Conference on Proteome Analysis. Antwerpen, 18-19 december 2008. Arthur Gitome - 15 september 2008. Statistical Genetics Conference. ULiège. - 16-18 september 2008. Course in Statistics in gene-mapping studies & SAS JMP
genomics, UCL-Bruxelles. - 23-25 september 2008. Non Clinical Statistics Conference, Leuven. - 13 oktober 2008. The 10th Johnson and Johnson Pharmaceutical Conference in
Statistics, Beerse. - 15-17 oktober 2008. 16th Annual meeting of the Belgian Statistical Society, Wépion-
Namur. Setia Pramana - 15 september 2008. Statistical Genetics Conference. ULiège. - 16-18 september 2008. Course in Statistics in gene-mapping studies & SAS JMP
genomics, UCL-Bruxelles. - 23-25 september 2008. Non Clinical Statistics Conference, Leuven. - 13 oktober 2008. The 10th Johnson and Johnson Pharmaceutical Conference in
Statistics, Beerse. - 15-17 oktober 2008. 16th Annual meeting of the Belgian Statistical Society, Wépion-
Namur.
Emanuele del Fava - 9-11 juni 2008. Final Meeting of the European project POLYMOD, Antwerpen Niel Hens - 12 december 2008. Workshop on Infectious Disease Epidemiology for Decision
Making. Brussel. Ivy Jansen - 15 februari 2008. Beerse. Annual Meeting of the Belgian Society for Mass
Spectrometry. - 15 september 2008, ULiège. Mini-Conference: Aspects of Statistical Genetics. - 22-26 september 2008. Cagliari, Sardinia. 7th European Conference on
Computational Biology (ECCB08) - 16-17 oktober 2008. 16th Annual Meeting of the Belgian Statistical Society, Wépion-
Namur. - 15-16 december 2008. Maastricht. Benelux. Bioinformatics Conference. - 18-19 december 2008. Maastricht, 3rd Symposium on Proteome Analysis. Ziv Shkedy - 16-17 oktober 2008. 16th Annual Meeting of the Belgian Statistical Society, Wépion-
Namur. Goele Massonnet - 18-20 september 2008. IAP Workshop Missing information in survival data beyond
right censoring. UGent. Paul Janssen - 29 maart – 6 april 2008. Conference of the Flemish rectors in Cuba. - 31 mei – 6 juni 2008. Launch of the IUC programme at Anton de Kom University,
Paramaribo, Suriname. - 8-14 december 2008. Jimma University en University of Addis Ababa, Ethiopia (IUC
and NSS, VLIR-UOS Development Cooperation). - 16-17 oktober 2008. 16th Annual meeting of the Belgian Statistical Society, Wépion-
Namur. Christel Faes - 24 oktober 2008. VEE Studiedag. Leuven. Binnenlandse bezoekers (seminarie) Dimitris Rizopoulos (KULeuven), 4 april 2008 Olivier Thas (UGent), 10-11 september 2008 Ingrid Van Keilegom (UCL), 10-11 september 2008 Tony Van Geneugden (Tibotec), 10-11 september 2008 Koen Kas (VIB, Gent), 12 september 2008