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    Copyright 2015 American Medical Association. All rig hts reserved.

    JAMA PATIENT PAGE | Gastroenterology

    Irritable Bowel Syndrome

    Irritable bowel syndrome (IBS) is a common cause of stomach pain,

    cramping, and changed bowel habits.

    What Causes IBS?

    Irritablebowelsyndromecandisruptnormalroutines.Butitisnotlife-

    threatening,norisitrelatedtoahigherriskofcancer.Ithasmanycauses.

    Forexample, yourbowelsmight contractabnormally. You mighthave

    changes in the bacteria in your bowels. Or you might be sensitive to

    stress or certain foods. Sometimes theseconditions can be triggered

    bysevereinfections.Othercausesarepossible.AClinicalReviewinthe

    March 3, 2015,issueofJAMAprovides more information on IBS.

    What Are the Symptoms?

    Stomach pain or cramping

    Changes in bowel habits (diarrhea,constipation, or both)Stomach bloatingor distention

    Intense urgesto move your bowels. Theseurgesmaynot berelated

    to having a bowel movement.

    Symptoms are often related to eating. Having a bowel movement

    oftenimproves IBS pain. Symptomsof IBS canchange.Yourdoctor

    might suspect another disorder if yoursymptoms started afterage

    50yearsorifyouhaveafamilyhistoryofotherboweldisorders.Your

    doctor also might suspect another disorder if youhave

    Unexplained weight loss

    Diarrhea at night or blood in your stool

    Unexplained iron deficiency

    What Makes the Symptoms Worse?

    Certain foods. Examples include those that contain lactose,

    fructose,or someothercarbohydrates. Otherexamples arefoods

    thatcontain gluten (found in wheat).

    Stress or anxiety

    Certain over-the-counter and prescription drugs

    Menstrual periods

    Severe infections affecting the stomach or bowels. Examples in-

    clude travelers diarrhea or food poisoning

    What CanBe Done?

    Doctors can diagnose IBS based on typical symptoms and a few

    simple tests. But doctors dont have reliable tests to determinethe

    precisecauseofIBS.Nosingletreatmentworksforeveryone.Sofind-

    ingthe right treatment cantake time andpatience.Treatments include

    Dietchange.Youmight,for example,stop eating gluten or certain

    carbohydrates. Ask your doctor or dietitian.

    Exercise

    Dietary fiber or fiber supplements (ifyou are constipated)

    Over-the-counter and prescription drugs

    Reducing stress or changing behaviors

    Treatments that affect the bacteria in your bowels. Your doctor

    might suggest probiotics. These provide helpful bacteria. Your

    doctor also might also suggest certain antibiotics. These change

    the type of bacteria already in your bowels.

    Authors: WilliamD. Chey, MD; Shanti Eswaran, MD; Jacob Kurlander, MD,MS

    ConflictofInterestDisclosures: TheauthorhascompletedandsubmittedtheICMJE

    Form forDisclosure ofPotentialConflictsof Interest andnonewerereported.

    Sources: International Foundationfor FunctionalGastrointestinal Disorders, IBS

    Self-helpand SupportGroup, American Collegeof Gastroenterology, American

    Gastroenterological Association

    TheJAMAPatient Pageis a publicservice ofJAMA. Theinformationand

    recommendations appearingon thispage areappropriate in mostinstances, butthey

    arenot a substitute formedicaldiagnosis. Forspecificinformation concerning your

    personal medical condition,JAMA suggests thatyou consultyour physician. Thispage

    maybe photocopiednoncommercially by physicians andother health care

    professionalsto sharewithpatients. Topurchase bulkreprints, call312/464-0776.

    FORMORE INFORMATION

    International Foundation for Functional GastrointestinalDisorders

    www.aboutibs.org

    IBS Self-help and Support Group

    www.ibsgroup.org/

    American College of Gastroenterology

    http://patients.gi.org/topics/irritable-bowel-syndrome/

    American Gastroenterological Association

    www.gastro.org/patient-center/digestive-conditions/irritable-bowel-

    syndrome

    To findthisand previous JAMA Patient Pages, go to thePatientPage link onJAMAswebsite atjama.com.Many areavailable in

    English and Spanish.

    982 JAMA March3, 2015 Volume313,Number 9 (Reprinted) jama.com

    Copyright 2015 American Medical Association. All rig hts reserved.

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