FOOD INTOLERANCE

FOOD INTOLERANCE(MALABSORBSI)A. PRASTOWOPENGERTIAN INTOLERANCE NON-IMMUNE-MEDIATED MERUPAKAN REAKSI MERUGIKAN DARI MAKANANEx Enzymatic food intolerance lactose intoleranceEx Pharmacological food intolerance biogenic amineEx Undefined reaksi merugikan food additiv tertentuADVERSE REACTION TO FOODIMMUNE-MEDIATEDNON-IMMUNE-MEDIATEDIgE-mediatedType I

Non-IgE-mediatedType IIType IIIType IV

EnzymaticPharmacologicalUndefined

Metabolic processLactose intolerance def lactase genetic mutation min 5 g lactose (Suarez, et al)Lipase pankreas /-Enzim protein pankreas /-Gangguan sekresi empedu/lesitinGluten intolerance celiac sprueContaminants/PharmacologicalBacteriaToxinsEffects of ingested food chemicals alcohol, caffeineDrugs Food additiveChinesse foodAbsorpsi Absorpsi air isoosmotikAbsorpsi ion Na, Cl, Bicarbonat

Malabsorpsi

Gangguan/gagal absorpsiBisa gangguan pencernaan

Malabsorpsi KHLactose Intolerance lactase low/free lactoseKegagalan pankreasSariawan idiopatikPenyakit seliak

LanjPenyebab Puasa > 48 jamAtropi vili2 ususPenurunan GALTPenurunan enzim pencernaan laktasePenyakit saluran cerna MakromolekulPenurunan enzim pencernaanGenetik Malabsorpsi KHKembungCramp perutMual laktose difermentasi di kolonMuntahDiare

Mal proteinGangguan pencernaan Polipetida kondisi usus halusSariawan idiopatikGangguan pankreas

LanjPenyebab PenyakitGangguan enzimatisGenetik

LanjDiare/gangguan saluran cernaSeperti manifestasi food alergiMalabsorbsi fatPenyakit empedu, pankreasGangguan enzimatisMal lemak fungsional/organik Steatore, kelelahan, penurunan BB, kembung, cramp, diare, mual muntahSariawan idiopatikGangguan empedu MCTGangguan pankreas MCTLipoprotein def

LanjSteatorKonstipasi Terima Kasih

Saluran Cerna

Liver

Peran organ pencernaan
Mouth Teeth//chewingTongue Amylase enzymeOesophagus Peristalsis/swallowingStomach Protease enzyme (pepsin)Enzymes and pHPancreasAmylase, Protease and Lipase EnzymesSmall intestine Amylase, Protease and Lipase EnzymesAbsorptionLarge intestine egestion