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Introduction (1) Biosequence exegesis Charles Lutwidge Dodgson (a.k.a. Lewis Carroll) Mathematician His fascination: Linguistics, Symbolic Logic, Number Theory, Cryptography, Probability Theory, & Geometry The author of Alice books Sequence Structure Function Role Lexicon Syntax Semantics Fragmatics
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KES 2004 Plasmid-DNAgram: Anagram Solving by Molecular Computing
Based on GFP-Expressing Plasmid DNA 3223 2, 31, 3 1School of
Computer Science & Engineering, SNU 2School of Biological
Sciences, SNU 3Interdisciplinary Program in Cognitive Science, SNU
Introduction (1) Biosequence exegesis
Charles Lutwidge Dodgson (a.k.a. Lewis Carroll) Mathematician His
fascination: Linguistics, Symbolic Logic, Number Theory,
Cryptography, Probability Theory, & Geometry The author of
Alice books Sequence Structure Function Role Lexicon Syntax
Semantics Fragmatics Introduction (2) Plasmid-DNAgram
FRET (Fluorescent Resonance Energy Transfer) BFP-GFP pair CFP-YFP
pair GFP-RFP pair (?) Cameleon FRET Cameleon : chimeric protein
(CFP-CaM-M13-YFP) [Ca2+] : CaM-M13 Biomolecular FRET for
Plasmid-DNAgram Anagram Rearrange the letters of nor do we to make
one word.
Herlock Sholmes vs. Sherlock Holmes Plasmid-DNAgram Fluorescent
Resonance Energy Transfer
Frster equation Biomolecular FRET Cameleon FRET Cameleon FRET for
Plasmid-DNAgram
Sequence Structure Function Role Lexicon Syntax Semantics
Fragmatics GFP CFP/YFP FRET [Ca2+] Biomolecular FRET for Plasmid
DNAgram
HEK293T cell CFP FRET YFP