KIMIA ANALITIK I

Visi Misi Prodi S1 Kimia

• Visi

• Menjadi pusat pengembangan ilmu kimia berbasis riset di

Indonesia bagian Barat, khususnya sains kimia sumber daya

alam lokal menjelang tahun 2035

• Misi

• Menyelenggarakan pendidikan tinggi di bidang ilmu kimia

yang terfokus pada sains kimia sumber daya alam lokal

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lokal mengacu pada keberlanjutan ekosistem

• Menerapkan dan menyebarluaskan ilmu kimia yang relevan

dengan potensi sumber daya alam lokal dan pengembangan

masyarakat melalui tridharma PT

WHAT IS ANALYTICAL CHEMISTRY?

Qualitative: provides information about the identity of

an atomic, molecular or biomolecular species

Quantitative: provides numerical information as to the

relative amounts of species

Analytical chemistry seeks ever improved means of

measuring the chemical composition of natural and

artificial materials

The techniques of this science are used to identify the

substances which may be present in a material and

determine the exact amounts of the identified substances

Definitions from www.acs.org

What is Analytical Chemistry ?

- Analytical chemistry deals with separating, identifying, and quantifying the

relative amounts of the components of an analyte.

The Role of Analytical Chemistry

-Friedrich Wilhelm Ostwald

“Analytical Chemistry, or the art of

recognizing different substances and

determining their constituents, takes a

prominent position among the

applications of science, since the

questions which it enables us to answer

arise wherever chemical processes are

employed for scientific or chemical

purposes.”

http://www.pace.edu/dyson/academics/chemistryplv/

CLASIFICATION OF ANALYTICAL METHODS

Classical methods: early years (separation of analytes) via

precipitation, extraction or distillation

Qualitative: recognized by color, boiling point, solubility, taste

Quantitative: gravimetric or titrimetric measurements

Instrumental Methods: newer, faster, more efficient

Physical properties of analytes: conductivity, electrode potential,

light emission absorption, mass to charge ratio and fluorescence,

many more…

Several different areas of analytical chemistry:

1. Clinical analysis - blood, urine, feces, cellular fluids, etc., for use in diagnosis.

2. Pharmaceutical analysis - establish the physical properties, toxicity,

metabolites, quality control, etc.

3. Environmental analysis - pollutants, soil and water analysis, pesticides.

4. Forensic analysis - analysis related to criminology; DNA finger printing, finger

print detection; blood analysis.

5. Industrial quality control - required by most companies to control product

quality.

6. Bioanalytical chemistry and analysis - detection and/or analysis of biological

components (i.e., proteins, DNA, RNA, carbohydrates, metabolites,

etc.).

This often overlaps many areas. Develop new tools for basic and

clinical research.

APPLICATIONS

Fundamental Research

The formulation of new drugs and the examination of

meteorites.

Product Development

Development of alloys and polymer composites.

Product Quality Control

Analysis of raw materials and finished products.

APPLICATIONS

Monitoring and Control of Pollutants

Heavy metals and pesticides.

Assay

The metal content of ores.

Medical and Clinical Studies

Indicators of physiological disorders.

Food Analysis

Labelling and provenance

ANALYTICAL PROBLEMS AND THEIR

SOLUTION

The solutions of all analytical problems, both

qualitative and quantitative follow the same

basic pattern which can be described under

seven general headings.

ANALYTICAL PROBLEMS AND THEIR

SOLUTION

Choice of method

Sampling

Preliminary sample treatment

Separations

Final measurement

Method validation

Assessment of the results

Components of an Analytical Method

Perform measurement

(instrumentation)

Handbook, Settle

Compare results

with standards

Pretreat and prepare sample

Obtain and store sample

Apply required

statistical techniques

Verify results

Present information

Extract data

from sample

Covert data

into information

Transform

information into

knowledge

After reviewing results

might be necessary

to modify and repeat

procedure

GLOSSARY OF TERMS

Akurasi

Analit

Blanko

Kalibrasi

Konsentrasi

Limit deteksi

Ekuivalen

Interferens

Masking

Matriks

GLOSSARY OF TERMS

Metode

Presisi

Prosedur

Reagen

Sampel

Sensitivitas

Standard

Standarisasi

Validasi

Fundamentals of Analytical Chemistry

8th Edition

Douglas A. Skoog - Stanford University

Donald M. West - San Jose State University

F. James Holler - University of Kentucky

Stanley R. Crouch - Michigan State

University

ISBN 0-534-41797-3

992 pages Case Bound 8 X 10

Reference Book