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    impact of marie la farge case on forensic medicine and crime scene investigationThe primary study of toxicology concerns the dosage of poison used in an

    y situation. Almost every substance has the potential to be poisonous given theright circumstances, but whether or not it becomes dangerous depends on the amount of poison involved.

    symptoms of poisonson trial

    Toxicology was first systematized by the Spanish physician Matthieu Orfila (17871853). Toxicologists examine blood and tissues to ascertain the presence and quantity of drugs or poisons in a person's body. Toxicological reports can assist investigators by showing whether the drug ingested was fatal and the approximate time the drug was introduced into the body.

    http://www.crimelibrary.com/criminal_mind/forensics/toxicology

    Marie Lafarge, a Frenchwoman, was convicted of poisoning her husband with arsenic in1840. This was the first case in which someone was convicted mainly upon forensic analysis

    results. She had purchased arsenic from the apothecary saying that it was to beused to killthe rats that infested her house. Her husband, Charles Lafarge, fell ill and wasseen by adoctor. His condition was thought to be due to cholera, a disease that was common at thattime. Later, suspicions were aroused when residues of white powder were found ina glass hehad drunk from. Soon Charles was dead and samples from his body were taken for analysisusing tests which showed that he had ingested arsenic. Marie was brought beforethe court,found guilty and sentenced to life imprisonment.

    http://www.nationalstemcentre.org.uk/dl/91fa4fbd070d1be1cdded979f9339049d3ddc7d0/26577-catalyst23%204_548.pdf

    a man in his late twenties was complaining of severe stomach pains allegedly after eating a cake sent by his new wife who was reluctant to marry him in the first place.

    Evidence presented for the arrest consisted of testimonies regarding Marie's purchase of arsenic prior to her husband's iterminent stomach pains. This was admit

    ted but Marie interposed the defense of having bought said substance for mice control.

    Her trial, which encountered several delays, finally took place on September 2,1840. And being a woman of renowned charm, the public indisputably did not takeher case lightly. The controversy became the center of public discussions such that Paris newspapers regularly gave the public updates of the case, the court-house was always overcrowded, and that even later, inns could no longer accommodate outsiders who were likewise intrigued. Several articles even mention that it divided France into pro and con Lafarge factions.

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    "You must be just; you cannot be so if you let this woman escape,"said the prosecutor, whose opposition was the well-renowned M. Paillet as counsel for the defense. as the trial progressed, several chemists testified that arsenic was foundin the milk, eggnog and the box from which Brun saw Marie take the white powder.Some who studied the ----- also testified that arsenic was likewise found in Charles' vomit and stomach content.

    it was during this stage that Mathieu Orfila, the forerunner in the field of poisons at that time, was contacted by the defense lawyer. It was Orfila who suggested that the chemists use the recently formulated Marsh Test because the resultsallegedly obtained by the chemists, as to him, were inconclusive and unreliable. The prosecution's lawyers then moved for the adoption of said test to better determine whether or not Charles really died of arsenic poisoning. Another batchof chemists were then hired to reexamine the precipitate extracted from Charles'remains. This time, however, tests proved negative.

    The prosecution, however, were unsatisfied with the results and further moved toexhume Charles' body for further tests. The court acceded to this request despite finding the body in an advanced state of decomposition. However, after a series of tests were again conducted, results still yielded negative traces of arsenic. Unrelented, the prosecution now moved to invite experts from Paris. Orfila then arrived and personally assured the court that amounts of arsenic would be present in the victim's body, that this arsenic does not come from the apparatus n

    or the substances utilized in testing, that the amount of arsenic supersedes theminute levels found in the human body. It was then that the very man whose suggestion almost exonerated her weeks ago now declares her guilty.

    The jury later found her guilty and sentenced her to hard labor for life.