Lec10 Imaging

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    Ruedeekorn Suwannanon ,

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    Investigation-Test

    Symptoms and Signs do not lead to diagnosis

    Invasive

    Cost

    Time

    Change the management

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    Functional

    Functional

    --

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    18/108Mammogram

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    Iodinate contrast agent ()

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    Cerebral

    Angiogram

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    Safty of radiation imaging and

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    Safty of radiation imaging and

    iodinate contrast media

    Natural radiation

    Diagnostic imaging test

    X-rays (plain flim, fluoroscopy,

    IVP, intervention under

    fluoroscopy or CT guidance)

    CT scan Nuclear medicine study

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    Effective dose

    Dose : Millisievert (mSv)

    Background radiation exposure : 3 mSv per year

    Diagnostic imaging?

    For this procedure: * Your approximate effectiveradiation dose is:

    Comparable to natural backgroundradiation for:

    ** Additional lifetime risk of fatalcancer from examination:

    ABDOMINAL REGION:

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    Computed Tomography (CT)-Abdomen and

    Pelvis

    10 mSv 3 years Low

    Computed Tomography (CT)-Abdomen and

    Pelvis, repeated with and without contrast

    material

    20 mSv 7 years Moderate

    Computed Tomography (CT)-Colonography 10 mSv 3 years Low

    Intravenous Pyelogram (IVP) 3 mSv 1 year LowRadiography (X-ray)-Lower GI Tract 8 mSv 3 years Low

    Radiography (X-ray)-Upper GI Tract 6 mSv 2 years Low

    BONE:

    Radiography (X-ray)-Spine 1.5 mSv 6 months Very Low

    Radiography (X-ray)-Extremity 0.001 mSv 3 hours Negligible

    CENTRAL NERVOUS SYSTEM:

    Computed Tomography (CT)-Head 2 mSv 8 months Very Low

    Computed Tomography (CT)-Head, repeated

    with and without contrast material

    4 mSv 16 months Low

    Computed Tomography (CT)-Spine 6 mSv 2 years Low

    CHEST:

    Computed Tomography (CT)-Chest 7 mSv 2 years Low

    Computed Tomography (CT)-Chest Low Dose 1.5 mSv 6 months Very Low

    Radiography-Chest 0.1 mSv 10 days Minimal

    DENTAL:

    Intraoral X-ray 0.005 mSv 1 day Negligible

    HEART:

    Coronary Computed Tomography Angiography

    (CTA)

    12 mSv 4 years Low

    Cardiac CT for Calcium Scoring 3 mSv 1 year Low

    MEN'S IMAGING:

    Bone Densitometry (DEXA) 0.001 mSv 3 hours Negligible

    NUCLEAR MEDICINE:

    Positron Emission Tomography Computed

    Tomography (PET/CT)

    25 mSv 8 years Moderate

    WOMEN'S IMAGING:

    Bone Densitometry (DEXA) 0.001 mSv 3 hours Negligible

    Mammography 0.4 mSv 7 weeks Very Low

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    Idionate contrastmedia safety

    Contrast allergy and adverse reaction

    Contrast induced nephropathy (CIN)**

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    MRI contrast agent

    Is it safe?

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    Safty of MRI and gadolinium contrast agent

    MRI

    1. No radiation

    2. High tissue contrast3. Claustrophobia

    4. Timing

    5. Prenancy ?

    Gadolinium contrast

    agent

    1. No iodine

    2. SE and adverse

    reaction : unusal

    3. Cross placenta (cat C

    by FDA)

    4. NSF***

    ( h i i fib i )

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    NSF (Nephrogenic systemic fibrosis)

    Feature Description

    Distribution Distal lower extremities > lower thighs > lower abdomen >

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    Distribution Distal lower extremities > lower thighs > lower abdomen >upper extremities

    Appearance Swelling, skin induration, skin-colored or erythematous papules with apeaudorange appearance, skin thickening with a woody texture

    Systemic involvement Skeletal muscle, myocardium, lungs, kidneys, testes, dura mater

    Time course From a few days to 3 months after exposure (median 25 days)

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    Pi l t i ff t

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    Piezoelectric effect

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    Possible biochemistry

    Not histology

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