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7/26/2019 Lec10 Imaging
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Ruedeekorn Suwannanon ,
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Investigation-Test
Symptoms and Signs do not lead to diagnosis
Invasive
Cost
Time
Change the management
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Functional
Functional
--
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Iodinate contrast agent ()
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Cerebral
Angiogram
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Safty of radiation imaging and
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Safty of radiation imaging and
iodinate contrast media
Natural radiation
Diagnostic imaging test
X-rays (plain flim, fluoroscopy,
IVP, intervention under
fluoroscopy or CT guidance)
CT scan Nuclear medicine study
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Effective dose
Dose : Millisievert (mSv)
Background radiation exposure : 3 mSv per year
Diagnostic imaging?
For this procedure: * Your approximate effectiveradiation dose is:
Comparable to natural backgroundradiation for:
** Additional lifetime risk of fatalcancer from examination:
ABDOMINAL REGION:
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Computed Tomography (CT)-Abdomen and
Pelvis
10 mSv 3 years Low
Computed Tomography (CT)-Abdomen and
Pelvis, repeated with and without contrast
material
20 mSv 7 years Moderate
Computed Tomography (CT)-Colonography 10 mSv 3 years Low
Intravenous Pyelogram (IVP) 3 mSv 1 year LowRadiography (X-ray)-Lower GI Tract 8 mSv 3 years Low
Radiography (X-ray)-Upper GI Tract 6 mSv 2 years Low
BONE:
Radiography (X-ray)-Spine 1.5 mSv 6 months Very Low
Radiography (X-ray)-Extremity 0.001 mSv 3 hours Negligible
CENTRAL NERVOUS SYSTEM:
Computed Tomography (CT)-Head 2 mSv 8 months Very Low
Computed Tomography (CT)-Head, repeated
with and without contrast material
4 mSv 16 months Low
Computed Tomography (CT)-Spine 6 mSv 2 years Low
CHEST:
Computed Tomography (CT)-Chest 7 mSv 2 years Low
Computed Tomography (CT)-Chest Low Dose 1.5 mSv 6 months Very Low
Radiography-Chest 0.1 mSv 10 days Minimal
DENTAL:
Intraoral X-ray 0.005 mSv 1 day Negligible
HEART:
Coronary Computed Tomography Angiography
(CTA)
12 mSv 4 years Low
Cardiac CT for Calcium Scoring 3 mSv 1 year Low
MEN'S IMAGING:
Bone Densitometry (DEXA) 0.001 mSv 3 hours Negligible
NUCLEAR MEDICINE:
Positron Emission Tomography Computed
Tomography (PET/CT)
25 mSv 8 years Moderate
WOMEN'S IMAGING:
Bone Densitometry (DEXA) 0.001 mSv 3 hours Negligible
Mammography 0.4 mSv 7 weeks Very Low
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Idionate contrastmedia safety
Contrast allergy and adverse reaction
Contrast induced nephropathy (CIN)**
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MRI contrast agent
Is it safe?
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Safty of MRI and gadolinium contrast agent
MRI
1. No radiation
2. High tissue contrast3. Claustrophobia
4. Timing
5. Prenancy ?
Gadolinium contrast
agent
1. No iodine
2. SE and adverse
reaction : unusal
3. Cross placenta (cat C
by FDA)
4. NSF***
( h i i fib i )
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NSF (Nephrogenic systemic fibrosis)
Feature Description
Distribution Distal lower extremities > lower thighs > lower abdomen >
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Distribution Distal lower extremities > lower thighs > lower abdomen >upper extremities
Appearance Swelling, skin induration, skin-colored or erythematous papules with apeaudorange appearance, skin thickening with a woody texture
Systemic involvement Skeletal muscle, myocardium, lungs, kidneys, testes, dura mater
Time course From a few days to 3 months after exposure (median 25 days)
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Pi l t i ff t
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Piezoelectric effect
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Possible biochemistry
Not histology
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