Modul Etiology

8/13/2019 Modul Etiology

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Candidiasis and chronic hyperplastic Candidiasis, and has been found to be more

common in females than males.

4. Denture Lining MaterialsFor the prosthodontics treatment ang management of traumatized oral mucosa denture

lining materials wich include tissue conditioners and soft denture liners, are widely used.

Denture lining materials are most commonly used in association with the mandibular

denture. Recently materials wich are available are their silicone elastomers, plasticized

higher mathecrylate polymers, hydrophilic polymethacrylates or fluoropolymers.

Candidal growth has been associated with mandibular denture relined with soft liner. The

most commonly detected yeasts were strains of the genus Candida, in particular C.

albicans, C. glabarataand C. tropicalis (P.S Wrigth, et. al, 1985).

5. Denture PlaquePoor denture hygiene is considered to be one of the etiologic for factors denture

stomatitis. Various factors stimulating yeast proliferation, such as poor aral hygiene, high

carbohydrate intake, reduce salivary flow, composition of saliva, design of the prosthesis

and continuous denture wearing can also enhance the pathogenicity of denture plaque (J.

Budtz, et. al, 2007).

6. Surface Texture and Permeability of Denture BaseThe tissue surface the dentures usually shows micropits and mictoporosities.

Microorganisms harboring in these areas are difficult to remove mechanically or by

chemical cleansing. According to several in vitrostudies, the microbial contamination of

denture acrylic resin occurs very quickly, and yeasts seem to adhere well to denture

materials. Surface roughness may facilitate ,icrobial retention and infection. The porosity

and surface texture of acrylic resin were investigated, and it was found that the denture

surface with a fine texture with an absence of porosity did not allow attachment of plaque

by penetration of surface defect or by mechanical fixation to surface irregulerities. In

vitrostudy, Van Reenen showed that C. albicans penetrated the commonly used acrylic

resin; penetration of the unpolish surface that is in contact with the mucosa was greater

than that of the polished surface. It was further confirmed with the used of a fluorescent

(JF. R Van, 1973).


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7. Allergenic Condition/ReactionToxicity is usually manifestated by the release of several chemical constituents from the

material, which can induces an allergic response in term of localized or generalized

stomatitis/ mutagenic effect. An allergenic reaction to constituens of the denture material

in the form of contact mucositis is also suggested. The reaction may be related to the

presence of resin monomer, hydroquinone peroxide, dimethyl-p-toluidine, or

methacrylate in the denture. Furthermore, contact sensitivities are more common to occur

with cold or autoplymerized resins than with heat-cured denture-base materials. Several

forms of allergenies including type IV hypersensitivity, urticarial, allergic stomatitis,

dermatitis and psoriasis have been reported in literature from deiffenrent polymer

components (J. Verran, et. al, 1997).

8. Systematic FactorsIn cases that fail to respond to the usual treatments, consider the role of systemic

conditions such as diabetes mellitus, nutritional deficiencis (iron, folate, or vitamin B12),

hypothyroidism, immunocompromised conditions (HIV infection), malignancies (acute

leukemia, agranulocytosis), iatrogenic immunosuppressive drugs, e.g. Corticosteroids,

may also predispose the host to candida-associated denture stomatitis (FR. Pires, et. al,

2002).

Prognosis and complication

If untreated, denture stomatitis can cause soreness and palatal inflammatory papillary

hyperplasia and may lead to poorly fitting dentures in the future. The administration of topical

antifungal therapy, removal of mechanical traumatism caused by the denture and reinforcement

or hygienic measures, ease the disappearance of the lesions. However, local recurrences are

frequent if aetiopathologic factors persist.

The prognosis of this disorder is good, as malignant transformation has not been reported,

although continuous aspiration and swallowing of Candida speciesmay rarely have potentially

fatal consequences in immunocompromised patients.


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reference

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