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上上上上上上上上上上上上上 Shanghai Caerulum Pharma Discovery Co., Ltd . Tel 021-69018966/021-64556190 Fax 021-69018968 website www.caerulumpharma.com email : sales- [email protected] 1

Overview of Caerulumpharma (1)

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Page 1: Overview of Caerulumpharma (1)

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上海喀露蓝科技有限公司公司Shanghai Caerulum Pharma Discovery Co., Ltd.

Tel: 021-69018966/021-64556190 Fax: 021-69018968 website: www.caerulumpharma.com email : [email protected]

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Product catalogue

Overview

Workshops & In house QC equipments

Contents

Major business & Strengths

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About us

Established since 2012. We are a chemical service company to assist customers for the drug discovery and development. 

Our laboratory: ☆ 4 standard ☆ 3 pilot ☆ 1 multifunctional ☆ 1 analysis

Our team member: ☆ 18 chemists ☆ 5 Customer Service ☆ 1 QA & 2QC ☆ 2 Account department ☆ 2 HR & Administration

2012 2013 2014 2015051015202530

Growth chart

Laboratory Staff

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Managing Director

Synthesis Department

FTE

Production

R&D

Quality Assurance

Quality Control

Account Department

Cost control

Customer Service

Quotation

Promotion

Information

Operation Department

HR

Operation Safety

Inventory

Organization Chart

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Standard laboratory

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Pilot laboratory

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In house QC Equipments

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Equipment List-laboratory

Equipment ListSerial number Name Size/Model Quantity

1 Reactor100L 550L 2

2 Multifunctional Reactor 50L 1

3 Rotary Evaporator20L 61L 3

4 Low temperature circulation Pump

DLSB-5L/20℃ 1DLSB-5L/-25℃ 1

DLSB-10L/-25℃ 8DLSB-20L/30℃ 1DLSB-30L/-30℃ 1DLSB-30L/-30℃ 1DLSB-50L/-40℃ 1DLSB-30L/-40℃ 4

5 High temperature circulation PumpGSC-30 2

50L/200℃ 2

6 High and low temperature circulating pumpGDX-100L/-40℃ 3GDX-50L/-40℃ 1

7 Oil Pump8L 14L 42L 1

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Cooperated factory

500-3000L Reactors Centrifuge

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Equipment List-cooperated factory

Equipment List

Serial number Name Size/Model Quantity

1 Glass Reactor 100L 4

2 Enamel Reactor500L 1

2000L 53000L 2

3 Cryogenic Reactor300L 1

1000L 14 Stainless steel filter 300L 25 Lobe Pump -  26 Water Pump -  67 Rotary Evaporator 50L 1

8 Double cone Dryer1000L 12000L 1

9 Drying oven 48 Batches 1

10 Centrifuge800RMP 1

1000RMP 1

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Major business

FTE projects

Custom Synthesis

R&D

Major business

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Exclusive R&D team and

equipments for each group

A full set of SOP for safe

production and quality

assurance

Attach much importance to confidentiality and customers’

copyright

A B

Exclusive FTE laboratory

C

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Inquiry

Costing

Quotation

Contract & Confidentiality

Synthesis

Delivery

After sale service

Note: We will respond with quotation in 2 business days. We provide COA , MOA, ROS, MSDS and relevant spectra along with consignment.

Custom synthesis workflow

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Synthesis focus

Diabetes

GPCR

DPPIV

SGLT2

Cancer

ALK

CDK

BTK

B-Raf

FGFR

EGFR

Others

FLT3

Bcr-Ab1

JAK

LABA

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Our strengths

Customized service

Latest product synthesis

Strict confidentiality

Instant communication

Safety control

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Detailed weekly report, supplier list and real-time CCTV system

Relative structures comparison

Original data packed for new drug application

Cloud database and synchronized experiment records are available

Customized service

1616

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Weekly report

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Batch records

Besides keep detailed experimental records,batch records for scale up are well managed.

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Core products

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Computer is strictly for internal use. No USB is allowed in laboratory.

Experiment records are handled by authorized people.

Strict confidentiality

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Instant communication

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Product catalogue

Type 2 diabetes; DPP-4  CPDA0048 (2R,3S,5R)-2-(2,5-difluorophenyl)-5-(2-(methylsulfonyl)pyrrolo[3,4-c]pyrazol-5(2H,4H,6H)-yl)tetrahydro-2H-pyran-3-amine

1226781-44-7Omarigliptin;MK-3102Type 2 diabetes

Merck Serono, ApprovedDPP-4

  CPDD0802 CPDD08011443380-88-8 1280210-79-8

(2S,3R,5S)-2-(2,5-difluorophenyl)-5-(2-(methylsulfonyl)pyrrolo[3,4-c]pyrazol-5(2H,4H,6H)-yl)tetrahydro-2H-pyran-3-amine

tert-butyl 4,6-dihydropyrrolo[3,4-c]pyrazole-5(2H)-carboxylate

  CPDD0839 CPDD0232

6573-19-9(free base)1819364-02-7

1226781-82-3

2,4,5,6-tetrahydropyrrolo[3,4-c]pyrazole 4-methylbenzenesulfonate

tert-butyl 2-(methylsulfonyl)-4,6-dihydropyrrolo[3,4-c]pyrazole-5(2H)-carboxylate

O

H2N

NN

N SO

OF

F

F

F

ON

H2N

NN

Ms

BocN NN

SOO

BocN NHN

HN NHN

S OOOH

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With heart, our professional team always serve you the best.

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Thanks for your attention !