Publikationsverzeichnis 1990-2015 · 2016-02-24 · Virus Genes 48 (2014) 184-8 Full F, Jungnickl D, Reuter N, Bogner E, Brulois K, Scholz B, Stürzl M, Myoung J, Jung JU, Stamminger

Institut für Medizinische Virologie HELMUT-RUSKA-HAUS

Publikationsverzeichnis1990-2015

Berichte des Instituts für Virologie, Band 25 (2015)

Institut für Medizinische VirologieHelmut-Ruska-Haus

CharitéCentrum für diagnostische und präventive Labormedizinund

Labor Berlin Charité-Vivantes GmbHFachbereich Virologie

Direktor: Univ.-Prof. Dr. med. D. H. KrügerNationales Konsiliarlaboratorium für Hantaviren

Charitéplatz 110117 Berlin

Tel. +49-30-450-52 50 92Fax +49-30-450-52 59 07

http://virologie-ccm.charite.de/http://www.laborberlin.com

Abbildung auf dem Deckblatt:

Elektronenoptische Darstellung von Hantaviren, Typ Puumalavirus.Aufnahme: H. Gelderblom, Berlin

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Inhaltsverzeichnis

Vorwort ...................................................................................................................................... 4

Team des Instituts 2013 ......................................................................................................... 6

Publikationen 1990 bis 2015 .................................................................................................. 7

Original- und Übersichtsarbeiten in referierten Zeitschriften .............................................................. 7

Buchbeiträge ..................................................................................................................................... 61

Die 10 am häufigsten zitierten Publikationen 1990-2015 ................................................ 69

Anlagen ................................................................................................................................... 71

Öffentliche Institutskolloquien/Gastvorlesungen 2015 ...................................................................... 71

„Seminarsprecher des Jahres“ des Instituts für Virologie ................................................................. 72

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Vorwort

Ebola, MERS, Geflügelgrippe und dann auch noch Zika – die

Medien des Jahres 2015 waren voll mit der Darstellung von

Gefahren durch Virusinfektionen. Dabei wird oft vergessen,

dass auch Infektionen durch viele „alte“ Viren nach wie vor

große Probleme für die Medizin verkörpern. Die Medizinische

Virologie als Fachgebiet kann nur bestehen und sich weiter ent-

wickeln, wenn Forschung, Lehre und Krankenversorgung als

Einheit unter gemeinsamer strategischer Leitung gebündelt sind und direkt interagieren. Dies

ist auch die Voraussetzung dafür, dass die Virologie die gegenwärtigen und zukünftigen

Anforderungen aus der klinischen Praxis erfüllen kann. Deshalb erstaunt es, wenn an einigen

Medizinischen Fakultäten unseres Landes die Notwendigkeit eigenständiger virologischer

Lehrstühle in Frage gestellt oder die virologische Diagnostik kurzerhand „ausgelagert“ wird.

Wie sich solche politisch und wirtschaftlich motivierten Entscheidungen auf die Qualität des

Infektionsmanagements in Deutschland auswirken, wird die Zukunft zeigen.

In den vergangenen 26 Jahren, in denen ich das Institut geleitet habe, sind wir sehr bewusst

den Weg einer „translatorischen Virologie“ gegangen, in der die Aufklärung molekularer

Grundlagen mit dem Potential der klinisch-diagnostischen, -therapeutischen und -prophylak-

tischen Anwendung verknüpft wurde. Das betrifft nicht nur unsere Arbeiten zur Biologie, Dia-

gnostik und Klinik der Infektionen durch Hantaviren, sondern auch durch Hepatitisviren sowie

durch Cytomegalie- und Herpes-simplex-Viren, zur Immunpathologie von Virusinfektionen, zur

Entwicklung neuer molekularer Träger für Impfstoffe, bis hin zur Aufklärung der Wirkungsweise

von Restriktionsendonukleasen und ihrer Nutzung in der molekularen Diagnostik.

Im vorangegangenen Jahresbericht (Berichte des Instituts für Virologie, Band 24, 2014,

http://virologie-ccm.charite.de/institut/jahresberichte/) haben wir ausführlich die inhaltlichen

Ergebnisse der Tätigkeit unserer Arbeitsgruppen in Forschung, Lehre und Krankenversorgung

dargestellt. Dies soll hier ergänzt werden durch ein gesammeltes Publikationsverzeichnis seit

1990, das auch das Jahr 2015 einschließt. Die Titel der Publikationen ermöglichen eine Über-

sicht über das Spektrum unserer Themen. Bei Publikationen in Zeitschriften mit einem aktuel-

len Impact (bzw. Impact im Erscheinungsjahr der Arbeit) von mehr als 10 Punkten haben wir

zur breiteren Information auch das jeweilige Abstract angefügt. Die sich anschließende

Zitationsanalyse gibt die „Top 10“-Arbeiten wieder, die am häufigsten in der internationalen

Literatur zitiert wurden.

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Das Vorwort soll nicht enden ohne den herzlichen Dank an alle Mitarbeiter des Instituts, die

nicht nur 2015 Hervorragendes geleistet haben, und an all unsere Kooperationspartner,

Freunde und Unterstützer.

Berlin, 01. Februar 2016

Univ.-Prof. Dr. med. Detlev H. Krüger

Institutsdirektor

Ich danke Frau Christina Grübel für die bewährte Redaktion des Jahresberichts.

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Team des Instituts 2013

Publikationen 1990 bis 2015 Original- und Übersichtsarbeiten 2015

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Publikationen 1990 bis 2015

Original- und Übersichtsarbeiten in referierten Zeitschriften

2015 Allers K, Puyskens A, Epple HJ, Schürmann D, Hofmann J, Moos V, Schneider T: The effect of timing of antiretroviral therapy on CD4+ T-cell reconstitution in the intestine of HIV-infected patients. Mucosal Immunol. 2015 Jul 1 [Epub ahead of print] Drexler JF, Corman VM, Lukashev AN, van den Brand JM, Gmyl AP, Brünink S, Rasche A, Seggewiβ N, Feng H, Leijten LM, Vallo P, Kuiken T, Dotzauer A, Ulrich RG, Lemon SM, Drosten C; Hepatovirus Ecology Consortium (including Krüger DH): Evolutionary origins of hepatitis A virus in small mammals. Proc. Natl. Acad. Sci. U. S. A. 112 (2015) 15190-5 Haag LM, Hofmann J, Kredel LI, Holzem C, Kühl AA, Taube ET, Schubert S, Siegmund B, Epple HJ: Herpes simplex virus sepsis in a young woman with Crohn's disease. J. Crohns Colitis 9 (2015) 1169-73 Hofmann J, Grunert HP, Donoso-Mantke O, Zeichhardt H, Kruger DH: Does proficiency testing improve the quality of hantavirus serodiagnostics? Experiences with INSTAND EQA schemes. Int. J. Med. Microbiol. 305 (2015) 607-11 Klein F, Neuhaus R, Hofmann J, Rudolph B, Neuhaus P, Bahra M: Successful treatment of chronic hepatitis E after orthotopic liver transplantation with ribavirin monotherapy. Exp. Clin. Transplant. 13 (2015) 283-6 Kobak L, Raftery MJ, Voigt S, Kühl AA, Kilic E, Kurth A, Witkowski P, Hofmann J, Nitsche A, Schaade L, Krüger DH, Schönrich G: Hantavirus-induced pathogenesis in mice with a humanized immune system. J. Gen. Virol. 96 (2015) 1258-63 Kouadio L, Nowak K, Akoua-Koffi C, Weiss S, Allali BK, Witkowski PT, Krüger DH, Couacy-Hymann E, Calvignac-Spencer S, Leendertz FH: Lassa Virus in Multimammate Rats, Côte d'Ivoire, 2013. Emerg. Infect. Dis. 21 (2015) 1481-3 Kruger DH, Figueiredo LTM, Song JW, Klempa B: Hantaviruses – globally emerging pathogens. J. Clin. Virol. 64 (2015) 128-36 Kruger DH, Tkachenko EA, Morozov VG, Yunicheva YV, Pilikova OM, Malkin G, Ishmukhametov AA, Heinemann P, Witkowski PT, Klempa B, Dzagurova TK: Life-threatening Sochi virus infections, Russia. Emerg. Infect. Dis. 21 (2015) 2204-8 Pfuhl C, Oechtering J, Rasche L, Gieß RM, Behrens JR, Wakonig K, Freitag E, Pache FC, Otto C, Hofmann J, Eberspächer B, Bellmann-Strobl J, Paul F, Ruprecht K: Association of serum Epstein-Barr nuclear antigen-1 antibodies and intrathecal immunoglobulin synthesis in early multiple sclerosis. J. Neuroimmunol. 285 (2015) 156-60


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Sadeghi M, Lahdou I, Ettinger J, Navid MH, Daniel V, Zeier M, Hofmann J, Opelz G, Schnitzler P: Association of low serum TGF-β level in hantavirus infected patients with severe disease. BMC Immunol. 16 (2015) 19 Tkachenko EA, Witkowski PT, Radosa L, Dzagurova TK, Okulova NM, Yunicheva YV, Vasilenko L, Morozov VG, Malkin GA, Krüger DH, Klempa B: Adler hantavirus, a new genetic variant of Tula virus identified in Major’s pine voles (Microtus majori) sampled in southern European Russia. Infect. Genet. Evol. 29 (2015) 156-63 Van Bömmel F, Bartens A, Mysickova A, Hofmann J, Krüger DH, Berg T, Edelmann A: Serum hepatitis B virus RNA levels as an early predictor of HBeAg seroconversion during treatment with polymerase inhibitors. Hepatology 61 (2015) 66-76

Witkowski PT, Kallies R, Hoveka J, Auste B, Ithete NL, Šoltys K, Szemes T, Drosten C, Preiser W, Klempa B, Mfune JK, Kruger DH: Novel arenavirus isolates from Namaqua rock mice, Namibia, Southern Africa. Emerg. Infect. Dis. 21 (2015) 1213-6 Winkelbach A, Schade R, Schulz C, Wuertz S: Comparison of oral, rectal and intraperitoneal administration of IgY antibodies in passive immunization of rainbow trout (Oncorhynchus mykiss). Aquacult. Int. 23 (2015) 427-38 Witkowski PT, Leendertz SA, Auste B, Akoua-Koffi C, Schubert G, Klempa B, Muyembe-Tamfum JJ, Karhemere S, Leendertz FH, Krüger DH: Human seroprevalence indicating hantavirus infections in tropical rainforests of Côte d'Ivoire and Democratic Republic of Congo. Front. Microbiol. 21 (2015) 518


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2014 Drexler JF, Corman VM, Müller MA, Maganga GD, Vallo P, Binger T, Gloza-Rausch F, Cottontail VM, Rasche A, Yordanov S, Seebens A, Knörnschild M, Oppong S, Sarkodie YA, Pongombo C, Lukashev AN, Schmidt-Chanasit J, Stöcker A, Carneiro AJ, Erbar S, Maisner A, Fronhoffs F, Buettner R, Kalko EK, Kruppa T, Franke CR, Kallies R, Yandoko ER, Herrler G, Reusken C, Hassanin A, Krüger DH, Matthee S, Ulrich RG, Leroy EM, Drosten C: Corrigendum: Bats host major mammalian paramyxoviruses. Nat. Commun. 5 (2014) 3032 Eis-Hübinger AM, Reber U, Edelmann A, Kalus U, Hofmann J: Parvovirus B19 genotype 2 in blood donations. Transfusion 54 (2014) 1682-4 Frenzel K, Lehmann J, Krüger DH, Martin-Parras L, Uharek L, Hofmann J: Combination of immunoglobulins and natural killer cells in the context of CMV and EBV infection. Med. Microbiol. Immunol. 203 (2014) 115-23 Frey S, Essbauer S, Zöller G, Klempa B, Dobler G, Pfeffer M: Full genome sequence and preliminary molecular characterization of three tick-borne encephalitis virus strains isolated from ticks and a bank vole in Slovak Republic. Virus Genes 48 (2014) 184-8 Full F, Jungnickl D, Reuter N, Bogner E, Brulois K, Scholz B, Stürzl M, Myoung J, Jung JU, Stamminger T, Ensser A: Kaposi’s sarcoma associated herpesvirus tegument protein ORF75 is essential for viral lytic replication and plays a critical role in the antagonization of ND10-instituted intrinsic immunity. PLoS Pathog. 10 (2014) e1003863 Gelderblom HR, Krüger DH: Helmut Ruska (1908-1973): His role in the evolution of electron microscopy in the life sciences and especially virology. Adv. Imag. Electron Phys. 182 (2014) 1-94 Hofmann J, Meier M, Enders M, Führer A, Ettinger J, Klempa B, Schmidt S, Ulrich RG, Kruger DH: Hantavirus disease in Germany due to infection by Dobrava-Belgrade virus, genotype Kurkino. Clin. Microbiol. Infect. 20 (2014) O648-55 Johne R, Reetz J, Ulrich RG, Machowska P, Sachsenröder J, Nickel P, Hofmann J: An ORF1-rearranged hepatitis E virus derived from a chronically infected patient efficiently replicates in cell culture. J. Viral Hepat. 21 (2014) 447-56 Krüger DH, Hofmann J, Krautkrämer E, Zeier M: Bedrohung durch zoonotische Viren: Neues zur Hantavirus-Erkrankung Dtsch. Med. Wochenschr. 139 (2014) 1576-8 Lejeune A, Cremer M, von Bernuth H, Edelmann A, Modrow S, Bührer C: Persistent pure red cell aplasia in dicygotic twins with persistent congenital parvovirus B19 infection – remission following high dose intravenous immunoglobulin. Eur. J. Pediatr. 173 (2014) 1723-6 Okhrimenko A, Grün JR, Westendorf K, Fang Z, Reinke S, von Roth P, Wassilew G, Kühl AA, Kudernatsch R, Demski S, Scheibenbogen C, Tokoyoda K, McGrath MA, Raftery MJ, Schönrich G, Serra A, Chang HD, Radbruch A, Dong J: Human memory T cells from the bone marrow are resting and maintain long-lasting systemic memory. Proc. Natl. Acad. Sci. USA 111 (2014) 9229-34 Otto C, Hofmann J, Finke C, Zimmermann M, Ruprecht K: The fraction of varicella zoster virus-specific antibodies among all intrathecally-produced antibodies discriminates between patients with varicella zoster virus reactivation and multiple sclerosis. Fluids Barriers CNS 11 (2014) 3


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Paeschke R, Woskobojnik I, Makarov V, Schmidtke M, Bogner E: DSTP-27 prevents entry of human cytomegalovirus. Antimicrob. Agents Chemother. 58 (2014) 1963-71 Raftery MJ, Lalwani P, Krautkrämer E, Peters T, Scharffetter-Kochanek K, Krüger R, Hofmann J, Seeger K, Krüger DH, Schönrich G: β2 integrin mediates hantavirus-induced release of neutrophil extracellular traps. J. Exp. Med. 211 (2014) 1485-97

Raftery MJ, Wolter E, Fillatreau S, Meisel H, Kaufmann SH, Schönrich G: NKT cells determine titer and subtype profile of virus-specific IgG antibodies during herpes simplex virus infection. J. Immunol. 192 (2014) 4294-302 Ruprecht K, Wunderlich B, Gieß R, Meyer P, Loebel M, Lenz K, Hofmann J, Rosche B, Wengert O, Paul F, Reimer U, Scheibenbogen C: Multiple sclerosis: the elevated antibody response to Epstein-Barr virus primarily targets, but is not confined to, the glycine-alanine repeat of Epstein-Barr nuclear antigen-1. J. Neuroimmunol. 272 (2014) 56-61 Schmidt S, Essbauer SS, Mayer-Scholl A, Poppert S, Schmidt-Chanasit J, Klempa B, Henning K, Schares G, Groschup MH, Spitzenberger F, Richter D, Heckel G, Ulrich RG: Multiple infections of rodents with zoonotic pathogens in Austria. Vector-Borne Zoonot. Dis. 14 (2014) 467-75 Slovák M, Kazimírová M, Siebenstichová M, Ustaníková K, Klempa B, Gritsun T, Gould EA, Nuttall PA: Survival dynamics of tick-borne encephalitis virus in Ixodes ricinus ticks. Ticks Tick-Borne Dis. 5 (2014) 962-9 Witkowski PT, Klempa B, Ithete NL, Auste B, Mfune JK, Hoveka J, Matthee S, Preiser W, Kruger DH: Hantaviruses in Africa. Virus Res. 187 (2014) 34-42 Zvierbliene A, Kucinskaite-Kodze I, Razanskiene A, Petraityte-Burneikiene R, Klempa B, Ulrich RG, Gedvilaite A: The use of chimeric virus-like particles harbouring a segment of hantavirus Gc glycoprotein to generate a broadly-reactive hantavirus-specific monoclonal antibody. Viruses 6 (2014) 640-60


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2013 Bogner E, Pecher G: Pattern of the epitope-specific IgG/IgM response against Human Cytomegalovirus in patients with multiple myeloma. Clin. Vaccine Immunol. 20 (2013) 1298-304 Deuschle K, Hofmann J, Otto C, Bellmann-Strobl J, Scherner O, Klumbies K, Schneider E, Broddack J, Paul F, Ruprecht K: Are there Epstein-Barr virus seronegative patients with multiple sclerosis? Mult. Scler. 19 (2013) 1242 Drexler JF, Corman VM, Müller MA, Lukashev AN, Gmyl A, Coutard B, Adam A, Ritz D, Leijten LM, van Riel D, Kallies R, Klose SM, Gloza-Rausch F, Binger T, Annan A, Adu-Sarkodie Y, Oppong S, Bourgarel M, Rupp D, Hoffmann B, Schlegel M, Kümmerer BM, Krüger DH, Schmidt-Chanasit J, Sétien AA, Cottontail VM, Hemachudha T, Wacharapluesadee S, Osterrieder K, Bartenschlager R, Matthee S, Beer M, Kuiken T, Reusken C, Leroy EM, Ulrich RG, Drosten C: Evidence for novel hepaciviruses in rodents. PLoS Pathog. 9 (2013) e1003438 Edelmann A, Eichenlaub U, Lepek S, Krüger DH, Hofmann J: Performance of the MagNA Pure 96 system for cytomegalovirus nucleic acid amplification testing in clinical samples. J. Clin. Microbiol. 51 (2013) 1600-1 Frey S, Essbauer S, Zöller G, Klempa B, Weidmann M, Dobler G, Pfeffer M: Complete genome sequence of tick-borne encephalitis virus strain A104 isolated from a Yellow-Necked Mouse (Apodemus flavicollis) in Austria. Genome Announc. 1 (2013) 3-4. Hammoud B, Schmueck M, Fischer AM, Fuehrer H, Park SJ, Akyuez L, Schefold JC, Raftery MJ, Schönrich G, Kaufmann AM, Volk HD, Reinke P: HCMV-specific T-cell therapy: Do not forget supply of help. J. Immunother. 36 (2013) 93-101 Havlíková S, Ličková M, Klempa B: Non-viraemic transmission of tick-borne viruses. Acta Virol. 57 (2013) 123-9 Klempa B, Avsic-Zupanc T, Clement J, Dzagurova TK, Henttonen H, Heyman P, Jakab F, Kruger DH, Maes P, Papa A, Tkachenko EA, Ulrich RG, Vapalahti O, Vaheri A: Complex evolution and epidemiology of Dobrava-Belgrade hantavirus: definition of genotypes and their characteristics. Arch. Virol. 158 (2013) 521-9 Klempa B, Koulemou K, Auste B, Emmerich P, Thomé-Bolduan C, Günther S, Koivogui L, Krüger DH, Fichet-Calvet E: Seroepidemiological study reveals regional co-occurrence of Lassa- and Hantavirus antibodies in Upper Guinea, West Africa. Trop. Med. Int. Health 18 (2013) 366-71 Klempa B, Radosa L, Kruger DH: The broad spectrum of hantaviruses and their hosts in Central Europe. Acta Virol. 57 (2013) 130-7 Korup S, Rietscher J, Calvignac-Spencer S, Trusch F, Hofmann J, Moens U, Sauer I, Voigt S, Schmuck R, Ehlers B: Identification of a novel human polyomavirus in organs of the gastrointestinal tract. PLoS One 8 (2013) e58021


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Krüger DH, Ulrich RG, Hofmann J: Hantaviruses as zoonotic pathogens in Germany. Dtsch. Arztebl. Int. Ed. 110 (2013) 461-7 Lalwani P, Raftery MJ, Kobak L, Rang A, Giese T, Mathaei M, van den Elsen PJ, Wolff T, Krüger DH, Schönrich G: Hantaviral mechanisms driving HLA class I antigen presentation require both RIG-I and TRIF. Eur. J. Immunol. 43 (2013) 2566-76 Mackeldanz P, Alves J, Möncke-Buchner E, Wyszomirski KH, Krüger DH, Reuter M: Functional consequences of mutating conserved SF2 helicase motifs in the Type III restriction endonuclease EcoP15I translocase domain. Biochimie 95 (2013) 817-23 Pounder KC, Begon M, Sironen T, Henttonen H, Watts PC, Voutilainen L, Vapalahti O, Klempa B, Fooks AR, McElhinney LM: Novel hantavirus in field vole, United Kingdom. Emerg. Infect. Dis. 19 (2013) 673-5 Radosa L, Schlegel M, Gebauer P, Ansorge H, Heroldová M, Jánová E, Stanko M, Mošanský L, Fričová J, Pejčoch M, Suchomel J, Purchart L, Groschup MH, Krüger DH, Ulrich RG, Klempa B: Detection of shrew-borne hantavirus in Eurasian pygmy shrew (Sorex minutus) in Central Europe. Infect. Genet. Evol. 19 (2013) 403-10 Scuda N, Madinda NF, Akoua-Koffi C, Adjogoua EV, Wevers D, Hofmann J, Cameron KN, Leendertz SAJ, Couacy-Hymann E, Robbins M, Boesch C, Jarvis MA, Moens U, Mugisha L, Calvignac-Spencer S, Leendertz FH, Ehlers B: Novel polyomaviruses of nonhuman primates: Genetic and serological predictors for the existence of multiple unknown polyomaviruses within the human population. PLoS Pathog. 9 (2013) e1003429 Tkachenko EA, Bernshtein AD, Dzagurova TK, Morozov VG, Slonova RA, Ivanov LI, Trankvilevsky DV, Kruger DH: Actual problems of Hemorrhagic Fever with Renal Syndrome (in Russian). J. Microbiol. Epidemiol. Immunobiol. (Moscow) 1 (2013) 51-8 Ulrich RG, Imholt C, Krüger DH, Krautkrämer E, Scheibe T, Eßbauer SS, Pfeffer M: Hantaviren in Deutschland: Gefahren für Zoo-, Heim-, Haus- und Nutztier? Berl. Münch. Tierärztl. Wochenschr. 126 (2013) 514-26 Weber M, Gawanbacht A, Habjan M, Rang A, Borner C, Schmidt AM, Veitinger S, Jacob R, Devignot S, Kochs G, García-Sastre A, Weber F: Incoming RNA virus nucleocapsids containing a 5’-triphosphorylated genome activate RIG-I and antiviral signaling. Cell Host & Microbe 13 (2013) 1-11

Weidmann M, Frey S, Freire CCM, Essbauer S, Růžek D, Klempa B, Zubrikova D, Vögerl M, Pfeffer M, Hufert FT, Zanotto PM, Dobler G: Molecular phylogeography of tick-borne encephalitis virus in central Europe. J. Gen. Virol. 94 (2013) 2129-39


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Wengert O, Rothenfusser-Korber E, Vollrath B, Bohner G, Scheibe F, Otto C, Hofmann J, Angstwurm K, Ruprecht K: Neurosarcoidosis: correlation of cerebrospinal fluid findings with diffuse leptomeningeal gadolinium enhancement on MRI and clinical disease activity. J. Neurol. Sci. 335 (2013) 124-30 Wolk K, Witte K, Witte E, Raftery M, Kokolakis G, Philipp S, Schönrich G, Warszawska K, Kirsch S, Prösch S, Sterry W, Volk HD, Sabat R: IL-29 is produced by TH17 cells and mediates the cutaneous antiviral competence in psoriasis. Science Transl. Med. 5 (2013) 204ra129


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2012 Dremsek P, Wenzel JJ, Johne R, Ziller M, Hofmann J, Groschup MH, Werdermann S, Mohn U, Dorn S, Motz M, Mertens M, Jilg W, Ulrich RG: Seroprevalence study in forestry workers from eastern Germany using novel genotype 3- and rat hepatitis E virus-specific immunoglobulin G ELISAs. Med. Microbiol. Immunol. 201 (2012) 189-200 Drexler JF, Corman VM, Müller MA, Maganga GD, Vallo P, Binger T, Gloza-Rausch F, Rasche A, Yordanov S, Seebens A, Oppong S, Sarkodie YA, Pongombo C, Lukashev AN, Schmidt-Chanasit J, Stöcker A, Carneiro AJ, Erbar S, Maisner A, Fronhoffs F, Buettner R, Kalko EK, Kruppa T, Franke CR, Kallies R, Yandoko ER, Herrler G, Reusken C, Hassanin A, Krüger DH, Matthee S, Ulrich RG, Leroy EM, Drosten C: Bats host major mammalian paramyxoviruses. Nature Commun. 3 (2012) 796, 1-12

Dzagurova TK, Witkowski PT, Tkachenko EA, Klempa B, Morozov VG, Auste B, Zavora DL, Iunicheva IV, Mutnih ES, Kruger DH: Isolation of Sochi virus from a fatal case of hantavirus disease with fulminant clinical course. Clin. Infect. Dis. 54 (2012) e1-4 Eckerle I, Jakob E, Hofmann J, Schmidt-Bacher A, Ettinger J, Schnitzler P: Atypical severe Puumala hantavirus infection with virus sequence analysis from the patient and regional reservoir host. Zoon. Publ. Health 59 (2012) 110-5 Ettinger J, Geyer H, Nitsche A, Zimmermann A, Brune W, Sandford GR, Hayward GS, Voigt S: Complete genome sequence of the English isolate of rat cytomegalovirus (murid herpesvirus 8). J. Virol. 86 (2012) 13838 Ettinger J, Hofmann J, Enders M, Tewald F, Oehme RM, Rosenfeld UM, Ali HS, Schlegel M, Essbauer S, Osterberg A, Jacob J, Reil D, Klempa B, Ulrich RG, Kruger DH: Multiple synchronous outbreaks of Puumala virus, Germany, 2010. Emerg. Infect. Dis. 18 (2012) 1461-4 Frenzel K, Ganepola S, Michel D, Thiel E, Krüger DH, Uharek L, Hofmann J: Antiviral function and efficacy of polyvalent immunoglobulin products against CMV isolates in different human cell lines. Med. Microbiol. Immunol. 201 (2012) 277-86 Hofmann J, Führer A, Bolz M, Waldschläger-Terpe J, Meier M, Lüdders D, Enders M, Oltmann A, Meisel H, Krüger DH: Hantavirus infections by Puumala or Dobrava-Belgrade virus in pregnant women. J. Clin. Virol. 55 (2012) 266-9


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Klempa B, Witkowski PT, Popugaeva E, Auste B, Koivogui L, Fichet-Calvet E, Strecker T, Ter Meulen J, Krüger DH: Sangassou virus, the first hantavirus isolate from Africa, displays genetic and functional properties distinct from those of other murinae-associated hantaviruses. J. Virol. 86 (2012) 3819-27 Krautkrämer E, Krüger DH, Zeier M: Recent outbreaks of hantavirus disease in Germany and in the United States. Kidney Int. 82 (2012) 1243-5 Liman P, Babel N, Schachtner T, Unterwalder N, König J, Hofmann J, Reinke P, Nickel P: Mannose-binding lectin deficiency is not associated with increased risk for polyomavirus nephropathy. Transpl. Immunol. 26 (2012) 123-7 Loyen M, Helmchen U, Hofmann J, Krüger DH, Clasen W: Von Mäusen auf Menschen – Erkenntnisse aus der Hantavirus-Epidemie 2010. Dtsch. Med. Wochenschr. 137 (2012) 309-13 Meissner CS, Suffner S, Schauflinger M, von Einem J, Bogner E: A leucin zipper motif of a tegument protein triggers final envelopment of Human Cytomegalovirus. J. Virol. 86 (2012) 3370-82 Popugaeva E, Witkowski PT, Schlegel M, Ulrich RG, Auste B, Rang A, Krüger DH, Klempa B: Dobrava-Belgrade hantavirus from Germany shows receptor usage and innate immunity induction consistent with the pathogenicity of the virus in humans. PLoS One 7 (2012) e35587 Pritschet K, Donhauser N, Schuster P, Ries M, Haupt S, Kittan NA, Korn K, Pöhlmann S, Holland G, Bannert N, Bogner E, Schmidt B: CD4- and dynamin-dependent endocytosis of HIV-1 into plasmacytoid dendritic cells. Virology 423 (2012) 152-64 Rosche B, Laurent S, Conradi S, Hofmann J, Ruprecht K, Harms L: Measles IgG antibody correlates with T2 lesion load on MRI in patients with early Multiple Sclerosis. PLoS One 7 (2012) e28094 Sarıgüzel N, Hofmann J, Canpolat AT, Türk A, Ettinger J, Atmaca D, Akyar I, Yücel S, Arıkan E, Uyar Y, Cağlayık DY, Kocagöz AS, Kaya A, Kruger DH: Dobrava hantavirus infection complicated by panhypopituitarism, Istanbul, Turkey, 2010. Emerg. Inf. Dis. 18 (2012) 1180-3 Sauerbrei A, Schäfler A, Hofmann J, Schacke M, Gruhn B, Wutzler P: Evaluation of three commercial Varicella-Zoster virus IgG enzyme-linked immunosorbent assays in comparison to the fluorescent-antibody-to-membrane-antigen test. Clin. Vacc. Immunol. 19 (2012) 1261-8 Schlegel M, Radosa L, Rosenfeld UM, Schmidt S, Triebenbacher C, Löhr PW, Fuchs D, Heroldová M, Jánová E, Stanko M, Mošanský L, Fričová J, Pejčoch M, Suchomel J, Purchart L, Groschup MH, Krüger DH, Klempa B, Ulrich RG: Broad geographical distribution and high genetic diversity of shrew-borne Seewis hantavirus in Central Europe. Virus Genes 45 (2012) 48-55 Schlosser B, Stein A, Neuhaus R, Pahl S, Ramez B, Krüger DH, Berg T, Hofmann J: Liver transplant from a donor with occult HEV infection induced chronic hepatitis and cirrhosis in the recipient. J. Hepatol. 56 (2012) 500-2


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Steiner T, Ettinger J, Peng Z, Hofmann J, Hartmann M, Burkhardt M, Schnitzler P: Hyperintense lesion in the corpus callosum associated with Puumala hantavirus infection. J. Neurol. 259 (2012) 1742-5 Trusch F, Klein M, Finsterbusch T, Kühn J, Hofmann J, Ehlers B: Seroprevalence of the human polyomavirus 9 (1 HPyV9) and cross-reactivity to the African green monkey-derived lymphotropic polyomavirus (LPyV). J. Gen. Virol. 20 (2012) 698-705 Weiss S, Witkowski PT, Auste B, Nowak K, Weber N, Fahr J, Mombouli JV, Wolfe ND, Drexler JF, Drosten C, Klempa B, Leendertz FH, Kruger DH: Hantavirus in Bat, Sierra Leone. Emerg. Infect. Dis. 18 (2012) 159-61 Wyszomirski KH, Curth U, Alves J, Mackeldanz P, Möncke-Buchner E, Schutkowski M, Krüger DH, Reuter M: Type III restriction endonuclease EcoP15I is a heterotrimeric complex containing one Res subunit with several DNA-binding regions and ATPase activity. Nucleic Acids Res. 40 (2012) 3610-22 Yang CA, Raftery MJ, Hamann L, Guerreiro M, Grütz G, Haase D, Unterwalder N, Schönrich G, Schumann RR, Volk HD, Scheibenbogen C: Association of TLR3-hyporesponsiveness and functional TLR3 L412F polymorphism with recurrent herpes labialis. Hum. Immunol. 73 (2012) 844-51


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2011 Allers K, Hutter G, Hofmann J, Loddenkemper C, Rieger K, Thiel E, Schneider T: Evidence for the cure of HIV infection by CCR5Delta32/Delta32 stem cell transplantation. Blood 117 (2011) 2791-9

Charrel RN, Coutard B, Baronti C, Canard B, Nougairede A, Frangeul A, Morin B, Jamal S, Schmidt CL, Hilgenfeld R, Klempa B, de Lamballerie X: Arenaviruses and hantaviruses: From epidemiology and genomics to antivirals. Antiviral Res. 90 (2011) 102-14. Engler JB, Undeutsch R, Kloke L, Rosenberger S, Backhaus M, Schneider U, Egerer K, Dragun D, Hofmann J, Huscher D, Burmester GR, Humrich JY, Enghard P, Riemekasten G: Unmasking of autoreactive CD4 T cells by depletion of CD25 regulatory T cells in systemic lupus erythematosus. Ann. Rheum. Dis. 70 (2011) 2176-83 Kampmann SE, Schindele B, Apelt L, Bührer C, Garten L, Weizsaecker K, Krüger DH, Ehlers B, Hofmann J: Pyrosequencing allows the detection of emergent ganciclovir resistance mutations after HCMV infection. Med. Microbiol. Immunol. 200 (2011) 109-13 Krüger DH, Schönrich G, Klempa B: Human pathogenic hantaviruses and prevention of infection. Hum. Vaccin. 7 (2011) 685-93 Lee MH, Lalwani P, Raftery MJ, Matthaei M, Lütteke N, Kirsanovs S, Binder M, Ulrich RG, Giese T, Wolff T, Krüger DH, Schönrich G: RNA helicase retinoic acid-inducible gene I as a sensor of Hantaan virus replication. J. Gen. Virol. 92 (2011) 2191-200 Meissner CS, Köppen-Rung P, Dittmer A, Lapp S, Bogner E: A “coiled-coil” motif is important for oligomerization and DNA binding properties of human cytomegalovirus protein UL77. PLoS ONE 6 (2011) e25115 Mertens M, Essbauer SS, Rang A, Schröder J, Splettstoesser WD, Kretzschmar C, Krüger DH, Groschup MH, Mätz-Rensing K, Ulrich RG: Non-human primates in outdoor enclosures: Risk for infection with rodent-borne hantaviruses. Vet. Microbiol. 147 (2011) 420-5 Mertens M, Hofmann J, Petraityte-Burneikiene R, Ziller M, Sasnauskas K, Friedrich R, Niederstrasser O, Krüger DH, Groschup MH, Petri E, Werdermann S, Ulrich RG: Seroprevalence study in forestry workers of a non-endemic region in eastern Germany reveals infections by Tula and Dobrava-Belgrade hantaviruses. Med. Microbiol. Immunol. 200 (2011) 263-8 Otto C, Oltmann A, Stein A, Frenzel K, Schroeter J, Habbel P, Gartner B, Hofmann J, Ruprecht K: Intrathecal EBV antibodies are part of the polyspecific immune response in multiple sclerosis. Neurology 76 (2011) 1316-21


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Sauerbrei A, Bohn K, Heim A, Hofmann J, Weißbrich B, Schnitzler P, Hoffmann D, Zell R, Jahn G, Wutzler P, Hamprecht K: Novel resistance-associated mutations of thymidine kinase and DNA polymerase genes of herpes simplex virus type 1 and type 2. Antivir. Ther. 16 (2011) 1297-308 Scuda N, Hofmann J, Calvignac-Spencer S, Ruprecht K, Liman P, Kuhn J, Hengel H, Ehlers B: A novel human polyomavirus closely related to the African green monkey-derived lymphotropic polyomavirus. J. Virol. 85 (2011) 4586-90 Wang Y, Sun B, Volk HD, Prösch S, Kern F: Comparative study of the influence of proteasome inhibitor MG132 and ganciclovir on the cytomegalovirus-specific CD8(+) T-cell immune response. Viral Immunol. 24 (2011) 455-61 Weitz M, Kiessling C, Friedrich M, Prösch S, Höflich C, Kern F, Volk HD, Sterry W, Asadullah K, Döcke WE: Persistent CMV infection correlates with disease activity and dominates the phenotype of peripheral CD8+ T cells in psoriasis. Exp. Dermatol. 20 (2011) 561-7


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2010 Adamaszek M, Heinrich A, Rang A, Langner S, Khaw AV: Cerebral sinuvenous thrombosis associated with Lyme neuroborreliosis. J. Neurol. 257 (2010) 481-3 Allers K, Loddenkemper C, Hofmann J, Unbehaun A, Kunkel D, Moos V, Kaup FJ, Stahl-Hennig C, Sauermann U, Epple HJ, Schneider T: Gut mucosal FOXP3+ regulatory CD4+ T cells and nonregulatory CD4+ T cells are differentially affected by simian immunodeficiency virus infection in rhesus macaques. J. Virol. 84 (2010) 3259-69 Bogner E: Human cytomegalovirus packaging: an update on structure-function relationships. Future Virol. 5 (2010) 397-404 Edelmann A, Kalus U, Oltmann A, Stein A, Unbehaun A, Drosten C, Krüger DH, Hofmann J: Improvement of an ultrasensitive human immunodeficiency virus type 1 real-time reverse transcriptase-polymerase chain reaction targeting the long terminal repeat region. Transfusion 50 (2010) 685-92 Faber MS, Ulrich RG, Frank C, Brockmann SO, Pfaff GM, Jacob J, Krüger DH, Stark K: Steep rise in notified hantavirus infections in Germany, April 2010. Euro Surveill. 15 (2010) pii: 1954 Feiterna-Sperling C, Edelmann A, Nickel R, Magdorf K, Bergmann F, Rautenberg P, Schweiger B, Wahn V, Kruger DH, Hofmann J: Pandemic influenza A (H1N1) outbreak among 15 school-aged HIV-1-infected children. Clin. Infect. Dis. 51 (2010) e90-4 Gingelmaier A, Eberle J, Kost BP, Bogner JR, Hofmann J, Weissenbacher T, Kastner R, Friese K, Weizsaecker K: Protease inhibitor-based antiretroviral prophylaxis during pregnancy and the development of drug resistance. Clin. Infect. Dis. 50 (2010) 890-4 Guhl S, Franke R, Schielke A, Johne R, Krüger DH, Babina M, Rang A: Infection of in vivo differentiated human mast cells with hantaviruses. J. Gen. Virol. 91 (2010) 1256-61 Gutzeit C, Raftery MJ, Peiser M, Tischer KB, Ulrich M, Eberhardt M, Stockfleth E, Giese T, Sauerbrei A, Morita CT, Schönrich G: Identification of an important immunological difference between virulent varicella-zoster virus and its avirulent vaccine: viral disruption of dendritic cell instruction. J. Immunol. 185 (2010) 488-97 Handke W, Oelschlegel R, Franke R, Wiedemann L, Krüger DH, Rang A: Generation and characterization of genetic reassortants between Puumala and Prospect Hill hantavirus in vitro. J. Gen. Virol. 91 (2010) 2351-9 Hofmann J, Frenzel K, Minh BQ, von Haeseler A, Edelmann A, Ross SR, Berg T, Krüger DH, Meisel H: Quantitative detection and typing of hepatitis D virus in human serum by real-time polymerase chain reaction and melting curve analysis. Diagn. Microbiol. Infect. Dis. 67 (2010) 172-9 Kather A, Raftery MJ, Devi-Rao G, Lippmann J, Giese T, Sandri-Golding RM, Schönrich G: Herpes simplex virus type 1 (HSV-1)-induced apoptosis in human dendritic cells as a result of downregulation of cellular FLICE-inhibitory protein and reduced expression of HSV-1 antiapoptotic latency-associated transcript sequences. J. Virol. 84 (2010) 1034-46


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Kirsanovs S, Klempa B, Franke R, Lee MH, Schönrich G, Rang A, Krüger DH: Genetic reassortment between high-virulent and low-virulent Dobrava-Belgrade virus strains. Virus Genes 41 (2010) 319-28 Klempa B, Koivogui L, Sylla O, Koulemou K, Auste B, Krüger DH, ter Meulen J: Serological evidence of human hantavirus infections in Guinea, West Africa. J. Infect. Dis. 201 (2010) 1031-4 Lünemann JD, Tackenberg B, Stein A, Wandinger KP, Oertel WH, Wagner HJ, Münz C, Meisel H, Sommer N, Zipp F: Dysregulated Epstein-Barr virus infection in patients with CIDP. J. Neuroimmunol. 218 (2010) 107-18 Lütteke N, Raftery MJ, Lalwani P, Lee MH, Giese T, Voigt S, Bannert N, Schulze H, Krüger DH, Schönrich G: Switch to high-level virus replication and HLA class I upregulation in differentiating megakaryocytic cells after infection with pathogenic hantavirus. Virology 405 (2010) 70-80 Matsumura H, Yoshida K, Luo S, Kimura E, Fujibe T, Albertyn Z, Barrero RA, Krüger DH, Kahl G, Schroth GP, Terauchi R: High-throughput SuperSAGE for digital gene expression analysis of multiple samples using next generation sequencing. PLoS One 5 (2010) pii: e12010 Pruss A, Caspari G, Krüger DH, Blümel J, Nübling CM, Gürtler L, Gerlich WH: Tissue donation and virus safety: more nucleic acid amplification testing is needed. Transpl. Infect. Dis. 12 (2010) 375-86 Rang A: Modulation of innate immune responses by hantaviruses. Crit. Rev. Immunol. 30 (2010) 515-27 Ruokonen PC, Metzner S, Ücer A, Torun N, Hofmann J, Pleyer U: Intraocular antibody synthesis against rubella virus and other microorganisms in Fuchs’ heterochromic cyclitis. Graefes Arch. Clin. Exp. Ophthalmol. 248 (2010) 565-71 Scheibe F, Hofmann J, Ruprecht K: Parainfectious myelitis associated with parvovirus B19 infection. J. Neurol. 257 (2010) 1557-8 Schindele B, Apelt L, Hofmann J, Nitsche A, Michel D, Voigt S, Mertens T, Ehlers B: Improved detection of mutated human cytomegalovirus UL97 by pyrosequencing. Antimicrob. Agents Chemother. 54 (2010) 5234-41 Thoma C, Bogner E: Short hairpin RNAs specific to human cytomegalovirus terminase subunit pUL89 prevent viral maturation. Antivir. Ther. 15 (2010) 391-400 Witkowski PT, Schuenadel L, Wiethaus J, Bourquain D, Kurth A, Nitsche A: Cellular impedance measurement as a new tool for poxvirus titration, antibody neutralization testing and evaluation of antiviral substances. Biochem. Bioph. Res. Comm. 401 (2010) 37-41


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2009 Adlhoch C, Kaiser M, Pauli G, Koch J, Meisel H: Indigenous hepatitis E virus infection of a plasma donor in Germany. Vox Sang. 97 (2009) 303-8 Adlhoch C, Wolf A, Meisel H, Kaiser M, Ellerbrok H, Pauli G: High HEV presence in four different wild boar populations in East and West Germany. Vet. Microbiol. 139 (2009) 270-3 Benjamin S, Radermacher M, Kirchberger J, Schöneberg T, Edelmann A, Ruiz T: 3D structure of phosphofructokinase from Pichia pastoris: Localization of the novel γ-subunits. J. Struct. Biol. 168 (2009) 345-51 Deckers M, Hofmann J, Kreuzer KA, Reinhard H, Edubio A, Hengel H, Voigt S, Ehlers B: High genotypic diversity and a novel variant of human cytomegalovirus revealed by combined UL33/UL55 genotyping with broad-range PCR. Virol. J. 6 (2009) 210 Dzagurova TK*, Klempa B*, Tkachenko EA, Slyusareva GP, Morozov VG, Auste B, Krüger DH: Molecular diagnostics of hemorrhagic fever with renal syndrome during a Dobrava virus infection outbreak in the European part of Russia. J. Clin. Microbiol. 47 (2009) 4029-36 (* equal first authors) Handke W, Krüger DH, Rang A: Defective particles can lead to underestimated antibody titers in virus neutralization tests. Intervirology 52 (2009) 335-339 Handke W, Oelschlegel R, Franke R, Krüger DH, Rang A: Hantaan virus triggers TLR3-dependent innate immune responses. J. Immunol. 182 (2009) 2849-58 Havlíková S, Roller L, Koči J, Trimnell AR, Kazimírová, Klempa B, Nuttall PA: Functional role of 64P, the candidate transmission-blocking vaccine antigen from the tick, Rhipicephalus appendiculatus. Int. J. Parasitol. 39 (2009) 1485-93 Holzenburg A, Dittmer A, Bogner E: Assembly of monomeric human cytomegalovirus pUL104 into portal structures. J. Gen. Virol. 90 (2009) 2381-5 Hütter G, Nowak D, Mossner M, Ganepola S, Müßig A, Allers K, Schneider T, Hofmann J, Kücherer C, Blau O, Blau IW, Hofmann WK, Thiel E: Long-term control of HIV by CCR5 delta32/delta32 stem-cell transplantation. N. Engl. J. Med. 360 (2009) 692-8

Hwang JS, Schilf R, Drach JC, Townsend LB, Bogner E: Susceptibilities of human cytomegalovirus, clinical isolates and other herpesviruses to new acetylated, tetrahalogenated benzimidazole D-ribonucleosides. Antimicrob. Agents Chemother. 53 (2009) 5095-101


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Kalus U, Edelmann A, Pruss A, Hofmann J, Kiesewetter H, Krüger DH, Salama A: Noninfectious transfusion of platelets donated before detection of human immunodeficiency virus RNA in plasma. Transfusion 49 (2009) 435-9 Khasnatinov MA, Ustanikova K, Frolova TV, Pogodina VV, Bochkova NG, Levina LS, Slovak M, Kazimirova M, Labuda M, Klempa B, Eleckova E, Gould EA, Gritsun T: Non-hemagglutinating flaviviruses: Molecular mechanisms for the emergence of new strains via adaptation to European ticks. PLoS ONE 4 (2009) e7295 Klempa B: Hantaviruses and climate change. Clin. Microbiol. Inf. 15 (2009) 518-23 Klempa B, Krüger DH, Auste B, Stanko M, Krawczyk A, Nickel KF, Uberla K, Stang A: A novel cardiotropic murine adenovirus representing a distinct species of mastadenovirus. J. Virol. 83 (2009) 5749-59 Kramski M, Achazi K, Klempa B, Krüger DH: Nephropathia epidemica with a 6-week incubation period after occupational exposure to Puumala hantavirus. J. Clin. Virol. 44 (2009) 99-101 Kregler O, Schilf R, Lander A, Bannert N, Bogner E: Brefeldin A inhibits expression of DNA packaging proteins and nucleocapsid formation of human cytomegalovirus. FEBS Lett. 583 (2009) 1207-14 Krüger DH, Klempa B: Von der Maus zum Menschen: Gefahren durch Hantaviren. Berl. Münch. Tierärztl. Wochenschr. 122 (2009) 434-9 Le Coutre P, Meisel H, Hofmann J, Röcken C, Vuong GL, Neuburger S, Hemmati PG, Dörken B, Arnold R: Reactivation of hepatitis E infection in a patient with acute lymphoblastic leukaemia after allogenic stem cell transplantation. Gut 58 (2009) 699-702

Maes P, Klempa B, Clement J, Matthijnssens J, Gajdusek DC, Krüger DH, Van Ranst M: A proposal for new criteria for the classification of hantaviruses, based on S and M segment protein sequences. Infect. Genet. Evol. 9 (2009) 813-20 Möncke-Buchner E, Rothenberg M, Reich S, Wagenführ K, Matsumura H, Terauchi R, Krüger DH, Reuter M: Functional characterization and modulation of the DNA cleavage efficiency of type III restriction endonuclease EcoP15I in its interaction with two sites in the DNA target. J. Mol. Biol. 387 (2009) 1309-19


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Neeb L, Diekmann S, Blechschmidt C, Meisel H, Hofmann J, Harms L, Endres M: Infratentorial progressive multifocal leukencephalopathy in a patient with pulmonary sarcoidosis. J. Neurol. 256 (2009) 1936-8 Pingoud V, Wende W, Friedhoff P, Reuter M, Alves J, Jeltsch A, Mones L, Fuxreiter M, Pingoud A: On the divalent metal ion dependence of DNA cleavage by restriction endonucleases of the EcoRI family. J. Mol. Biol. 393 (2009) 140-60 Pleyer U, Metzner S, Hofmann J: Diagnostik und Differenzialdiagnostik bei akuter retinaler Nekrose. Ophthalmologe 106 (2009) 1074-82 Raftery MJ, Möncke-Buchner E, Matsumura H, Giese H, Winkelmann A, Reuter M, Terauchi R, Schönrich G, Krüger DH: Unravelling the interaction of HCMV with dendritic cells using SuperSAGE. J. Gen. Virol. 90 (2009) 2221-33 Schlegel M, Klempa B, Auste B, Bemmann M, Schmidt-Chanasit J, Büchner T, Groschup MH, Meier M, Balkema-Buschmann A, Zoller H, Krüger DH, Ulrich R: Dobrava-Belgrade virus spillover infections, Germany. Emerg. Infect. Dis. 15 (2009) 2017-20 Szczepek M, Mackeldanz P, Möncke-Buchner E, Alves J, Krüger DH, Reuter M: Molecular analysis of restriction endonuclease EcoRII from Escherichia coli reveals precise regulation of its enzymatic activity by autoinhibition. Mol. Microbiol. 72 (2009) 1011-21 Westhoff TH, Vergoulidou M, Loddenkemper C, Schwartz S, Hofmann J, Schneider T, Zidek W, van der Giet M: Chronic norovirus infection in renal transplant recipients. Nephrol. Dial. Transpl. 24 (2009) 1051-3


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2008 Coutard B, Gorbalenya AE, Snijder EJ, Leontovich AM, Poupon A, De Lamballerie X, Charrel R, Gould EA, Gunther S, Norder H, Klempa B, Bourhy H, Rohayem J, L'hermite E, Nordlund P, Stuart DI, Owens RJ, Grimes JM, Tucker PA, Bolognesi M, Mattevi A, Coll M, Jones TA, Aqvist J, Unge T, Hilgenfeld R, Bricogne G, Neyts J, La Colla P, Puerstinger G, Gonzalez JP, Leroy E, Cambillau C, Romette JL, Canard B: The VIZIER project: preparedness against pathogenic RNA viruses. Antiviral Res. 78 (2008) 37-46 Dorn DC, Lawatscheck R, Zvirbliene A, Aleksaite E, Pecher GT, Sasnauskas K, Özel M, Raftery MJ, Schönrich G, Ulrich R, Gedvilaite A: Cellular and humoral immunogenicity of hamster polyomavirus-derived virus-like particles harboring a mucin 1 cytotoxic T-cell epitope. Viral Immunol. 21 (2008) 12-27 Dzagurova TK, Tkachenko EA, Yunicheva YV, Morozov VG, Bryukhanov AF, Bashkirtsev VN, Sedova NS, Klempa B, Kruger DH: Discovery, clinical and etiological characteristic of hemorrhagic fever with renal syndrome in the subtropical zone of Krasnodar region (in Russian). Zh. Mikrobiol. (Moscow) 2008 (1), 12-6 Hofmann J, Meisel H, Klempa B, Vesenbeckh SM, Beck R, Michel D, Schmidt-Chanasit J, Ulrich RG, Grund S, Enders G, Kruger DH: Hantavirus outbreak, Germany, 2007. Emerg. Infect. Dis. 14 (2008) 850-2 Kaspari M, Tavalai N, Stamminger T, Zimmermann A, Schilf R, Bogner E: Proteasome inhibitor MG132 blocks viral DNA replication and assembly of human cytomegalovirus. FEBS Lett. 582 (2008) 666-72 Klempa B, Tkachenko EA, Dzagurova TK, Yunicheva YV, Morozov VG, Okulova NM, Slyusareva GP, Smirnov A, Kruger DH: Hemorrhagic fever with renal syndrome caused by 2 lineages of Dobrava hantavirus, Russia. Emerg. Infect. Dis. 14 (2008) 617-25 Märschenz S, Brinckmann A, Nürnberg P, Krüger DH, Günther S, Meisel H: Co-replication analyses of naturally occurring defective hepatitis B virus variants with wild-type. Virology 372 (2008) 247-59 Matsumura H, Reuter M, Krüger DH, Winter P, Kahl G, Terauchi R: SuperSAGE. Methods Mol. Biol. 387 (2008) 55-70 Matsumura H, Krüger DH, Kahl G, Terauchi R: SuperSAGE: A modern platform for genome-wide quantitative transcription profiling. Curr. Pharmaceut. Biotechnol. 9 (2008) 368-74 Oltmann A, Kämper S, Staeck O, Schmidt-Chanasit J, Günther S, Berg T, Frank C, Krüger DH, Hofmann J: Fatal outcome of hepatitis A virus (HAV) infection in a traveler with incomplete HAV vaccination and evidence of Rift Valley Fever virus infection. J. Clin. Microbiol. 46 (2008) 3850-2 Pruß A, Caspari G, Krüger DH, Blümel J, Nübling CM, Quenzel EM, Kalus U, Gerlich W, Gürtler L: Nukleinsäure-Amplifikationstests für HIV, HBV und HCV bei Gewebespendern: Sinnvoll oder überflüssig? Transfus. Med. Hemother. 35 (2008) 421-30


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Raftery MJ, Hitzler M, Winau F, Giese T, Kaufmann SHE, Schaible U, Schönrich G: Human cytomegalovirus interference in CD1 antigen presentation. J. Virol. 82 (2008) 4308-19 Raftery MJ, Winau F, Giese T, Kaufmann SHE, Schaible U, Schönrich G: Viral danger signals control CD1d de novo synthesis and NKT cell activation. Eur. J. Immunol. 38 (2008) 668-79 Schönrich G, Rang A, Lütteke N, Raftery MJ, Charbonnel N, Ulrich RG: Hantavirus-induced immunity in rodent reservoirs and humans. Immunol. Rev. 225 (2008) 163-89

Schmidt-Chanasit J, Meisel H, Hofmann J, Rang A, Lambrecht E, Ulrich RG, Doerr HW: Clinical course and laboratory parameters of the first Dobrava-Belgrade hantavirus infection imported to Germany. J. Clin. Virol. 42 (2008) 91-3


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2007 Braun S, Zajakina A, Aleksejeva J, Sharipo A, Bruvere R, Ose V, Pumpens P, Garoff H, Meisel H, Kozlovska T: Proteasomal degradation of core protein variants from chronic hepatitis B patients. J. Med. Virol. 79 (2007) 1312-21 Ganepola S, Gentilini C, Hilbers U, Lange T, Rieger K, Hofmann J, Maier M, Liebert UG, Niederwieser D, Engelmann E, Heilbronn R, Thiel E, Uharek L: Patients at high risk for CMV infection and disease show delayed CD8+ T-cell immune recovery after allogeneic stem cell transplantation. Bone Marrow Transpl. 39 (2007) 293-9 Hwang JS, Kregler O, Schilf R, Bannert N, Drach JC, Townsend LB, Bogner E: Identification of acetylated, tetrahalogenated benzimidazole D-ribonucleosides with enhanced activity against human cytomegalovirus. J. Virol. 81 (2007) 11604-11 Klempa B, Fichet-Calvet E, Lecompte E, Auste B, Aniskin V, Meisel H, Barrière P, Koivogui L, ter Meulen J, Krüger DH: Novel hantavirus sequences detected in a shrew, Guinea. Emerg. Infect. Dis. 13 (2007) 520-2 Kramski M, Meisel H, Klempa B, Krüger DH, Pauli G, Nitsche A: Detection and typing of human pathogenic hantaviruses by real-time RT-PCR and pyrosequencing. Clin. Chem. 53 (2007) 1899-905 Oelschlegel R, Krüger DH, Rang A: MxA-independent inhibition of Hantaan virus replication induced by type I and type II interferon in vitro. Virus Res. 127 (2007) 100-5 Pestka JM, Zeisel MB, Bläser E, Schürmann P, Bartosch B, Cosset FL, Patel AH, Meisel H, Baumert J, Viazov S, Rispeter K, Blum HE, Roggendorf M, Baumert TF: Rapid induction of virus-neutralizing antibodies and viral clearance in a single-source outbreak of hepatitis C. Proc. Natl. Acad. Sci. USA 104 (2007) 6025-30 Schilling S, Emmerich P, Klempa B, Auste B, Schnaith E, Schmitz H, Krüger DH, Günther S, Meisel H: Hantavirus outbreak in Germany: Limitations of routine serological diagnostics and clustering of virus sequences of human and rodent origin. J. Clin. Microbiol. 45 (2007) 3008-14 Wagenführ K, Pieper S, Mackeldanz P, Linscheid M, Krüger DH, Reuter M: Structural domains in the Type III restriction endonuclease EcoP15I: Characterization by limited proteolysis, mass spectrometry and insertional mutagenesis. J. Mol. Biol. 366 (2007) 93-102


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2006 Bleifuss E, Kammertoens T, Hutloff A, Quarcoo D, Dorner M, Straub P, Uckert W, Hildt E: The translocation motif of hepatitis B virus improves protein vaccination. Cell Mol. Life Sci. 63 (2006) 627-35 Bürckstümmer T, Kriegs M, Lupberger J, Pauli EK, Schmittel S, Hildt E: Raf-1 kinase associates with hepatitis C virus NS5A and regulates viral replication. FEBS Letters 580 (2006) 575-80 Dittmer A, Bogner E: Specific short hairpin RNA-mediated inhibition of viral DNA packaging of human cytomegalovirus. FEBS Letters 580 (2006) 838-40 Gedvilaite A, Dorn DC, Sasnauskas K, Pecher G, Bulavaite A, Lawatscheck R, Staniulis J, Dalianis T, Ramqvist T, Schönrich G, Raftery MJ, Ulrich R: Virus-like particles derived from major capsid protein VP1 of different polyomaviruses differ in their ability to induce maturation in human dendritic cells. Virology 354 (2006) 252-60 Klempa B, Fichet-Calvet E, Lecompte E, Auste B, Aniskin V, Meisel H, Denys C, Koivogui L, ter Meulen J, Krüger DH: Hantavirus in African wood mouse, Guinea. Emerg. Infect. Dis. 12 (2006) 838-40 Klempa B, Meisel H, Kruger DH, Ulrich R, Stanko M, Labuda M: Saaremaa hantavirus should not be confused with its dangerous relative, Dobrava virus – Authors’ reply. J. Clin. Microbiol. 44 (2006) 1609-11 Lupberger J, Mund A, Kock J, Hildt E: Cultivation of HepG2.2.15 on Cytodex-3: Higher yield of hepatitis B virus and less subviral particles compared to conventional culture methods. J. Hepatol. 45 (2006) 547-52

Märschenz S, Endres AS, Brinckmann A, Heise T, Kristiansen G, Nürnberg P, Krüger DH, Günther S, Meisel H: Functional analysis of complex hepatitis B virus variants associated with development of liver cirrhosis. Gastroenterology 131 (2006) 765-80


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Maluf KN, Gaussier H, Bogner E, Feiss M, Catalano CE: Assembly of bacteriophage lambda terminase into a viral DNA maturation and packaging machine. Biochemistry 45 (2006) 15259-68 Matsumura H, Bin Nasir KH, Yoshida K, Ito A, Kahl G, Krüger DH, Terauchi R: SuperSAGE array: the direct use of 26-base-pair transcript tags in oligonucleotide arrays. Nat. Methods 3 (2006) 469-74

Meisel H, Wolbert A, Razanskiene A, Marg A, Kazaks A, Sasnauskas K, Pauli G, Ulrich R, Krüger DH: Development of novel IgG, IgA and IgM enzyme immunoassays based on recombinant Puumala and Dobrava hantavirus nucleocapsid proteins. Clin. Vaccine Immunol. (formerly: Clin. Diagn. Lab. Immunol.) 13 (2006) 1349-57 Pattamadilok S, Lee BH, Kumperasart S, Yoshimatsu K, Okumura M, Nakamura I, Araki K, Khoprasert Y, Dangsupa P, Panlar P, Jandrig B, Kruger DH, Klempa B, Jakel T, Schmidt J, Ulrich R, Kariwa H, Arikawa J: Geographical distribution of hantaviruses in Thailand and potential human health significance of Thailand virus. Am. J. Trop. Med. Hyg. 75 (2006) 994-1002 Raftery MJ, Winau F, Kaufmann SHE, Schaible UE, Schönrich G: CD1 antigen presentation by human dendritic cells as a target for herpes simplex virus immune evasion. J. Immunol. 177 (2006) 6207-14 Rang A, Heider H, Ulrich R, Krüger DH: A novel method for cloning of non-cytolytic viruses. J. Virol. Methods 135 (2006) 26-31 Rosenthal HA, Fuchs-Kittowski K: Ein Neologismus für die Lebenswissenschaften – Bedarf, Ethik? Erwägen Wissen Ethik 17 (2006) 594-6 Schmidt J, Meisel H, Capria SG, Petraityte R, Lundkvist Å, Hjelle B, Vial PA, Padula P, Krüger DH, Ulrich R: Serological assays for the detection of human Andes hantavirus infections based on its yeast-expressed nucleocapsid protein. Intervirology 49 (2006) 173-84 Schmitz T, Kleinkauf N, Klempa B, Ringe H, Varnholt V, Grosch-Wörner I: Transmission of human immunodeficiency virus type 1 nevirapine resistance mutation K103N from a treatment-naïve mother to her child. Pediatr. Infect. Dis. J. 25 (2006) 275-6 Schürmann D, Elston R, Xu F, Kleinkauf N, Wünsche T, Suttorp N: Evolution of resistance during first-line treatment with boosted fosamprenavir is associated with baseline mutations. AIDS 20 (2006) 138-40 Stoeckl L, Funk A, Kopitzki A, Brandenburg B, Oess S, Will H, Sirma H, Hildt E: Identification of a structural motif crucial for infectivity of hepatitis B viruses. Proc. Natl. Acad. Sci. USA 103 (2006) 6730-4


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2005 Brandenburg B, Stockl L, Gutzeit C, Roos M, Lupberger J, Schwartlander R, Gelderblom H, Sauer IM, Hofschneider PH, Hildt E: A novel system for efficient gene transfer into primary human hepatocytes via cell-permeable hepatitis B virus-like particle. Hepatology 42 (2005) 1300-9

Bunde T, Kirchner A, Hoffmeister B, Habedank D, Hetzer R, Cherepnev G, Prösch S, Reinke P, Volk HD, Lehmkuhl H, Kern F: Protection from cytomegalovirus after transplantation is correlated with immediate early 1-specific CD8 T cells. J. Exp. Med. 201 (2005) 1031-6

Friedrich B, Wollersheim M, Brandenburg B, Foerste R, Will H, Hildt E: Induction of anti-proliferative mechanisms in hepatitis B virus producing cells. J. Hepatol. 43 (2005) 696-703


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Geldmacher A, Skrastina G, Petrovskis I, Krüger DH, Pumpens P, Ulrich R: A hantavirus nucleocapsid protein segment exposed on hepatitis B virus core particles is highly immunogenic in mice when applied without adjuvans or in the presence of pre-existing anti-core antibodies. Vaccine 23 (2005) 3973-83 Hillemann A, Brandenburg B, Schmidt U, Roos M, Smirnow I, Lemken ML, Lauer UM, Hildt E: Protein transduction with bacterial cytosine deaminase fused to the TLM intercellular transport motif induces profound chemosensitivity to 5-fluorocytosine in human hepatoma cells. J. Hepatol. 43 (2005) 442-50

Klempa B, Stanko M, Labuda M, Ulrich R, Meisel H, KrügerDH: Central european Dobrava hantavirus isolate from striped field mouse, Apodemus agrarius. J. Clin. Microbiol. 43 (2005) 2756-63 Knösel T, Meisel H, Borgmann A, Riebel T, Krenn V, Schewe C, Petersen L: Parvovirus B19 infection associated with unilateral cervical lymphadenopathy, apoptotic sinus histiocytosis, and prolonged fatigue. J. Clin. Pathol. 58 (2005) 872-5 Kraus AA, Priemer C, Heider H, Krüger DH, Ulrich R: Inactivation of Hantaan virus-containing samples for subsequent investigations outside biosafety level 3 facilities. Intervirology 48 (2005) 255-61 Krüger DH, Reuter M: Reliable detection of DNA cytosine methylation at CpNpG sites using the engineered restriction enzyme EcoRII-C. Biotechniques 38 (2005) 855-6 Liefeldt L, Plentz A, Klempa B, Kershaw O, Endres AS, Raab U, Neumayer HH, Meisel H, Modrow S: Recurrent high level parvovirus B19/genotype 2 viremia in a renal transplant recipient analyzed by real-time PCR for simultaneous detection of genotypes 1 to 3. J. Med. Virol. 75 (2005) 161-9 Mantke OD, Meyer R, Prösch S, Nitsche A, Leitmeyer K, Kallies R, Niedrig M: High prevalence of cardiotropic viruses in myocardial tissue from explanted hearts of heart transplant recipients and heart donors: a 3-year retrospective study from a German patients' pool. J. Heart Lung Transplant. 24 (2005) 1632-8 Matsumura H, Ito A, Saitoh H, Winter P, Kahl G, Reuter M, Krüger DH, Terauchi R: SuperSAGE. Cell. Microbiol. 7 (2005) 11-8 Meier J, Lienicke U, Tschirch E, Krüger DH, Wauer RR, Prösch S: Human cytomegalovirus reactivation during lactation and mother-to-child transmission in preterm infants. J. Clin. Microbiol. 43 (2005)1318-24


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Rang A, Linke B, Jansen B: Detection of RNA variants transcribed from the transgene in Roundup Ready soybean. Eur. Food Res. Technol. 220 (2005) 438-43 Rayes N, Seehofer D, Lullius SG, Stein A, May G, Kahl A, Frei U, Neuhaus P, Meisel H: Monitoring of human cytomegalovirus, HHV-6 and HHV-7 infection in kidney transplant recipients by molecular methods to predict HCMV disease after transplantation: a prospective study. Ann. Transplant. 10 (2005) 23-8 Sandmann S, Meisel H, Razanskiene A, Wolbert A, Pohl B, Krüger DH, Sasnauskas K, Ulrich R: Detection of human hantavirus infections in Lithuania. Infection 33 (2005) 66-72 Schmidt J, Jandrig B, Klempa B, Yoshimatsu K, Arikawa J, Meisel H, Niedrig M, Pitra C, Krüger DH, Ulrich R: Nucleocapsid protein of cell-culture adapted Seoul virus strain 80-39: Analysis of its encoding sequence, expression in yeast and immuno-reactivity. Virus Genes 30 (2005) 37-48 Schmidt J, Meisel H, Hjelle B, Krüger DH, Ulrich R: Development and evaluation of serological assays for detection of human hantavirus infections caused by Sin Nombre virus. J. Clin. Virol. 33 (2005) 247-53 Schroeder C, Heider H, Möncke-Buchner E, Lin TI: The influenza virus ion channel and maturation cofactor M2 is a cholesterol-binding protein. Eur. Biophys. J. 34 (2005) 52-66 Seehofer D, Rayes N, Neumann UP, Meisel H, Oettle H, Nussler NC, Jonas S, Langrehr JM, Neuhaus P: Changing impact of cytomegalovirus in liver transplantation – a single centre experience of more than 1000 transplantations without ganciclovir prophylaxis. Transpl. Int. 18 (2005) 941-8 Voigt S, Michel D, Kershaw O, Kuhl JS, Mertens T, Ebell W, Meisel H: Fatal reactivation of postnatal cytomegalovirus infection with rapid emergence of ganciclovir resistance in an infant after allogeneic stem cell transplantation. J. Clin. Microbiol. 43 (2005) 3551-4


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2004 Donoso-Mantke O, Meyer R, Prösch S, Niedrig M: Frequent detection of viral nucleic acids in heart valve tissue. J. Clin. Microbiol. 42 (2004) 2298-300 Drosten C, Nippraschk T, Manegold C, Meisel H, Brixner V, Roth WK, Apedjinou A, Günther S: Prevalence of hepatitis B virus DNA in anti-HBc-positive/HBsAg-negative sera correlates with HCV but not HIV serostatus. J. Clin. Virol. 29 (2004) 59-68 Ehlers I, Horke S, Reumann K, Rang A, Grosse F, Will H, Heise T: Functional characterization of the interaction between human La and hepatitis B virus RNA. J. Biol. Chem. 279 (2004) 43437-47 Gedvilaite A, Zvirbliene A, Staniulis J, Sasnauskas K, Krüger DH, Ulrich R: Segments of Puumala hantavirus nucleocapsid protein inserted into chimeric polyomavirus-derived virus-like particles induce a strong immune response in mice. Viral Immunol. 17 (2004) 51-68 Geldmacher A, Schmaler M, Krüger DH, Ulrich R: Yeast-expressed hantavirus Dobrava nucleocapsid protein induces a strong, long-lasting, and highly cross-reactive immune response in mice. Viral Immunol. 17 (2004) 115-22 Geldmacher A, Skrastina D, Petrovskis I, Borisova G, Berriman JA, Roseman AM, Crowther RA, Fischer J, Musema S, Gelderblom HR, Lundkvist A, Renhofa R, Ose V, Krüger DH, Pumpens P, Ulrich R: An amino-terminal segment of hantavirus nucleocapsid protein presented on hepatitis B virus core particles induces a strong and highly cross-reactive antibody response in mice. Virology 323 (2004) 108-19 Klempa B, Schütt M, Auste B, Labuda M, Ulrich R, Meisel H, Krüger DH: First molecular identification of human Dobrava virus infection in Central Europe. J. Clin. Microbiol. 42 (2004) 1322-5 Kraus AA, Raftery MJ, Giese T, Ulrich R, Zawatzky R, Hippenstiel S, Suttorp N, Krüger DH, Schönrich G: Differential antiviral response of endothelial cells after infection with pathogenic and nonpathogenic hantaviruses. J. Virol. 78 (2004) 6143-50 Möncke-Buchner E, Mackeldanz P, Krüger DH, Reuter M: Overexpression and affinity chromatography purification of the Type III restriction endonuclease EcoP15I for use in transcriptome analysis. J. Biotechnol. 114 (2004) 99-106 Müller DB, Raftery MJ, Kather A, Giese T, Schönrich G: Induction of apoptosis and modulation of c-FLIPL and p53 in immature dendritic cells infected with herpes simplex virus. Eur. J. Immunol. 34 (2004) 941-51 Raftery MJ, Wieland D, Gronewald S, Kraus AA, Giese T, Schönrich G: Shaping phenotype, function, and survival of dendritic cells by cytomegalovirus-encoded IL-10. J. Immunol. 173 (2004) 3383-91 Rasche FM, Uhel B, Ulrich R, Krüger DH, Karges W, Czock D, Hampl W, Keller F, Meisel H, von Müller L: Thrombocytopenia and acute renal failure in Puumala hantavirus infections. Emerg. Infect. Dis. 10 (2004) 1420-5


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Razanskiene A, Schmidt J, Geldmacher A, Ritzi A, Niedrig M, Lundkvist Å, Krüger DH, Meisel H, Sasnauskas K, Ulrich R: High yields of stable and highly pure nucleocapsid proteins of different hantaviruses can be generated in the yeast Saccharomyces cerevisiae. J. Biotechnol. 111 (2004) 319-33 Reich S, Gössl I, Reuter M, Rabe JP, Krüger DH: Scanning force microscopy of DNA translocation by the Type III restriction enzyme EcoP15I. J. Mol. Biol. 341 (2004) 337-43 Scholz M, Vogel JU, Hover G, Prösch S, Kotchetkov R, Cinatl J, Koch F, Doerr HW, Cinatl J Jr.: Thrombin induces Sp1-mediated antiviral effects in cytomegalovirus-infected human retinal pigment epithelial cells. Med. Microbiol. Immunol. 193 (2004) 195-203 Schütt M, Meisel H, Krüger DH, Ulrich R, Dalhoff K, Dodt C: Life-threatening Dobrava hantavirus infection with unusually extended pulmonary involvement. Clin. Nephrol. 62 (2004) 54-7 Seehofer D, Meisel H, Rayes N, Stein A, Langrehr JM, Settmacher U, Neuhaus P: Prospective evaluation of the clinical utility of different methods for the detection of human cytomegalovirus disease after liver transplantation. Am. J. Transplant. 4 (2004) 1331-7 Tavakoli S, Schwerin W, Rohwer A, Hoffmann S, Weyer S, Weth R, Meisel H, Diepolder H, Geissler M, Galle PR, Löhr HF, Böcher WO: Phenotype and function of monocyte derived dendritic cells in chronic hepatitis B virus infection. J. Gen. Virol. 85 (2004) 2829-36 Zhou XE, Wang Y, Reuter M, Mücke M, Krüger DH, Meehan EJ, Chen L: Crystal structure of Type IIE restriction endonuclease EcoRII reveals an autoinhibition mechanism by a novel effector-binding fold. J. Mol. Biol. 335 (2004) 307-19


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2003 Beutler T, Höflich C, Stevens PA, Krüger DH, Prösch S: Downregulation of the epidermal growth factor receptor by human cytomegalovirus infection in human fetal lung fibroblasts. Am. J. Respir. Cell Mol. Biol. 28 (2003) 86-94 Brenner S, Prösch S, Schenke-Layland K, Riese U, Gausmann U, Platzer C: cAMP-induced Interleukin-10 promoter activation depends on CCAAT/enhancer-binding protein expression and monocytic differentiation. J. Biol. Chem. 278 (2003) 5597-604 Döcke WD, Kießling C, Worm M, Friedrich M, Pruß A, Weitz M, Prösch S, Kern F, Volk HD, Sterry W, Asadullah K: Subclinical activation of latent cytomegalovirus (CMV) infection and anti-CMV immune response in patients with atopic dermatitis. Brit. J. Dermatol. 148 (2003) 954-63 Donoso-Mantke O, Meyer R, Prösch S, Pregla R, Hetzer R, Niedrig M: Nachweis viraler Genomstrukturen im Myokardgewebe von Herzklappenspendern. Z. Herz-Thorax Gefäßchir. 17 (2003) 1-8 Kazaks A, Dishlers A, Pumpens P, Ulrich R, Krüger DH, Meisel H: Mosaic particles formed by wild-type hepatitis B virus core protein and its deletion variants consist of both homo- and heterodimers. FEBS Letters 549 (2003) 157-62 Klempa B, Meisel H, Räth S, Bartel J, Ulrich R, Krüger DH: Occurrence of renal and pulmonary syndrome in a region of North-East Germany where Tula hantavirus circulates. J. Clin. Microbiol. 41 (2003) 4894-7 Klempa B, Schmidt HA, Ulrich R, Kaluz S, Labuda M, Meisel H, Hjelle B, Krüger DH: Genetic interaction between distinct Dobrava hantavirus subtypes in Apodemus agrarius and A. flavicollis in nature. J. Virol. 77 (2003) 804-9 Klempa B, Ulrich R, Meisel H, Krüger DH, Schmidt HA, Kaluz S, Labuda M, Hjelle B: Genetic interaction between Dobrava and Saaremaa hantaviruses: now or millions of years ago? Authors' reply. J. Virol. 77 (2003) 7157-8 Koch J, Liang M, Queitsch I, Kraus AA, Bautz EKF: Human recombinant neutralizing antibodies against Hantaan virus G2 protein. Virology 308 (2003) 64-73 Matsumura H, Reich S, Ito A, Saitoh H, Kamoun S, Winter P, Kahl G, Reuter M, Krüger DH, Terauchi R: Gene expression analysis of plant host-pathogen interactions by SuperSAGE. Proc. Natl. Acad. Sci. USA 100 (2003) 15718-23


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Meisel H, Endres AS, Walther HU, Wend UC, Gerlich WH: Transmission of hepatitis B virus 2 months prior to hepatitis surface antigen positivity of donor blood. Transfus. Med. Hemother. 30 (2003) 228-31 Mücke M, Krüger DH, Reuter M: Diversity of Type II restriction endonucleases that require two DNA recognition sites. Nucl. Acids Res. 31 (2003) 6079-84 Prösch S, Priemer C, Höflich C, Liebenthal C, Babel N, Krüger DH, Volk HD: Proteasome inhibitors: a novel tool to suppress human cytomegalovirus replication and virus-induced immune modulation. Antiviral Ther. 8 (2003) 555-67 Roberts RJ, Belfort M, Bestor T, Bhagwat AS, Bickle TA., Bitinaite J, Blumenthal RM, Degtyarev SK, Dryden DTF, Dybvig K, Firman K, Gromova ES, Gumport RI, Halford SE, Hattman S, Heitman J, Hornby DP, Janulaitis A, Jeltsch A, Josephsen J, Kiss A, Klaenhammer TR, Kobayashi I, Kong H, Kruger DH, Lacks S, Marinus MG, Miyahara M, Murray NE, Nagaraja V, Piekarowicz A, Pingoud A, Raleigh E, Rao DN, Reich N, Repin VE, Selker EU, Shaw PC, Stein DC, Stoddard BL, Szybalski W, Trautner TA, Van Etten JL, Vitor JMB, Wilson GG, Xu SY: A nomenclature for restriction enzymes, DNA methyltransferases, homing endonucleases and their genes. Nucl. Acids Res. 31 (2003) 1805-12. Zhou XE, Wang Y, Reuter M, Mackeldanz P, Kruger DH, Meehan EJ, Chen L: A single mutation of restriction endonuclease EcoRII led to a new crystal form that diffracts to 2.1 A resolution. Acta Crystallogr. D. Biol. Crystallogr. 59 (2003) 910-2.


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2002 Dargeviciute A, Brus Sjölander K, Sasnauskas K, Krüger DH, Meisel H, Ulrich R, Lundkvist A: Yeast-expressed Puumala hantavirus nucleocapsid protein induces protection in a bank vole model. Vaccine 20 (2002) 3523-31 Donose-Mantke O, Meyer R, Prösch S, Pregla R, Hetzer R, Niedrig M: Nachweis viraler Genomstrukturen im Myokardgewebe von Herzklappenspendern. Z. Herz-Thorax-Gefäßchir. 17 (2003) 1-8 Endres AS, Helms T, Steinführer S, Meisel H: Transient broca aphasia in an elderly man caused by coxsackievirus B5. J. Neurol. 249 (2002) 1318-9 Foster AP, Brown PJ, Jandrig B, Grosch A, Voronkova T, Scherneck S, Ulrich R: Polyoma virus infection in hamsters and trichoepitheliomas/cutaneous adnexal tumours. Veterinary Record 151 (2002) 13-7 Kazaks A, Lachmann S, Koletzki D, Petrovskis I, Dislers A, Ose V, Skrastina D, Gelderblom HR, Lundkvist Å, Meisel H, Borisova G, Krüger DH, Pumpens P, Ulrich R: Stop codon insertion restores the particle formation ability of hepatitis B virus core-hantavirus nucleocapsid protein fusions. Intervirology 45 (2002) 340-9 Liefeldt L, Buhl M, Schweickert B, Engelmann E, Sezer O, Laschinski P, Preuschof L, Neumayer HH: Eradication of parvovirus B19 infection after renal transplantation requires reduction of immunosuppression and high-dose immunoglobulin therapy. Nephrol. Dial. Transplant. 17 (2002) 1840-2 Lundkvist Å, Meisel H, Koletzki D, Lankinen H, Cifire F, Geldmacher A, Sibold C, Gött P, Vaheri A, Krüger DH, Ulrich R: Mapping of B-cell epitopes in the nucleocapsid protein of Puumala hantavirus. Viral Immunol. 15 (2002) 177-92 Möncke-Buchner E, Reich S, Mücke M, Reuter M, Messer W, Wanker EE, Krüger DH: Counting CAG repeats in the Huntington’s disease gene by restriction endonuclease EcoP15I cleavage. Nucl. Acids Res. 30 (2002) e83, 1-7 Mücke M, Grelle G, Behlke J, Kraft R, Krüger DH, Reuter M: EcoRII: a restriction enzyme evolving recombination functions? EMBO J. 21 (2002) 5262-8

Mücke M, Pingoud V, Grelle G, Kraft R, Krüger DH, Reuter M: Asymmetric photo-cross-linking pattern of restriction endonuclease EcoRII to the DNA recognition sequence. J. Biol. Chem. 277 (2002) 14288-93 Nolte C, Endres AS, Meisel H: Sensory ataxia in myelopathy with chronic hepatitis C infection. Neurology 59 (2002) 958


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Preikschat P, Günther S, Reinhold S, Will H, Budde K, Neumeyer HH, Krüger DH, Meisel H: Complex HBV populations with mutations in core promoter, C gene, and pre-S region are associated with development of cirrhosis in long-term renal transplant recipients. Hepatology 35 (2002) 466-77

Prösch S, Lienicke U, Priemer C, Flunker G, Seidel WF, Krüger DH, Wauer RR: Human adenovirus and human cytomegalovirus infections in preterm newborns: no association with bronchopulmonary dysplasia. Pediatr Res. 52 (2002) 219-24 Prösch S, Wuttke, R, Krüger DH, Volk HD: NF-kappaB – a potential therapeutic target for inhibition of human cytomegalovirus (re)activation? Biol. Chem. 383 (2002) 1601-9 Raftery MJ, Kraus AA, Ulrich R, Krüger DH, Schönrich G: Hantavirus infection of dendritic cells. J. Virol. 76 (2002) 10724-33 Raftery MJ, Schwag M, Diesner S, Egerer G, Schönrich G: Dendritic cells cross-presenting viral antigens derived from autologous cells as a sensitive tool for visualization of human cytomegalovirus-reactive CD8+ T cells. Transplantation 73 (2002) 998-1002 Sasnauskas K, Bulavaite A, Hale A, Jin L, Knowles WA, Gedvilaite A, Dargeviciute A, Bartkeviciute D, Zvirbliene A, Staniulis J, Brown DWG, Ulrich R: Generation of recombinant virus-like particles of human and non-human polyomaviruses in yeast Saccharomyces cerevisiae. Intervirology 45 (2002) 308-17 Sievers E, Neumann J, Raftery M, Schönrich G, Eis-Hubinger AM, Koch N: Glycoprotein B from strain 17 of herpes simplex virus type I contains an invariant chain homologous sequence that binds to MHC class II molecules. Immunology 107 (2002) 129-35 Sominskaya I, Paulij W, Jansons J, Sobotta D, Dreilina D, Sunnen C, Meisel H, Gerlich WH, Pumpens P: Fine-mapping of the B-cell epitope domain at the N-terminus of the preS2 region of the hepatitis surface antigen. J. Immunol. Methods 260 (2002) 251-61 Ulrich R, Hjelle B, Pitra C, Krüger DH: Emerging viruses: the case „hantavirus“. Intervirology 45 (2002) 318-27


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Ulrich R, Lomonossoff GP, Krüger DH: New developments in viral vaccine technologies. Editorial. Intervirology 45 (2002) 197-8 Von Müller L, Hampl W, Hinz J, Meisel H, Reip A, Engelmann E, Heilbronn R, Gärtner B, Krämer O, Einsele H, Hebart H, Ljubicic T, Löffler J, Mertens T: High variability between results of different in-house tests for cytomegalovirus (CMV) monitoring and a standardized quantitative plasma CMV PCR assay. J. Clin. Microbiol. 40 (2002) 2285-7 Voronkova T, Grosch A, Kazaks A, Ose V, Skrastina D, Sasnauskas K, Jandrig B, Arnold W, Scherneck S, Pumpens P, Ulrich R: Chimeric bacteriophage fr virus-like particles harboring the immunodominant C-terminal region of hamster polyomavirus VP1 induce a strong VP1-specific antibody response in rabbits and mice. Viral Immunol. 15 (2002) 627-44 Zhou X, Reuter M, Meehan EJ, Chen L: A new crystal form of restriction endonuclease EcoRII that diffracts to 2.8 Å resolution. Acta Crystallogr. D 58 (2002) 1343-5


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2001 Heider H, Ziaja B, Priemer C, Lundkvist Å, Neyts J, Krüger DH, Ulrich R: A chemiluminescence detection method of hantaviral antigens in neutralisation assays and inhibitor studies. J. Virol. Methods 96 (2001) 17-23 Krüger DH, Ulrich R, Lundkvist Å: Hantavirus infections and their prevention. Microbes Infect. 3 (2001) 1129-44 Leitmeyer K, Sibold C, Meisel H, Ulrich R, Labuda M, Krüger DH: First molecular evidence for Puumala hantavirus in Slovakia. Virus Genes 23 (2001) 165-70 Lin TI, Schroeder C: Definitive assignment of proton selectivity and attoampere unitary current to the M2 ion channel protein of influenza A virus. J. Virol. 75 (2001) 3647-56 Mücke M, Reich S, Möncke-Buchner E, Reuter M, Krüger DH: DNA cleavage by type III restriction-modification enzyme EcoP15I is independent of spacer distance between two head to head oriented recognition sites. J. Mol. Biol. 312 (2001) 687-98 Plyusnin, A, Krüger DH, Lundkvist Å: Hantaviruses in Europe. Adv. Virus Res. 57 (2001) 105-36 Prösch S, Heine AK, Volk HD, Krüger DH: CCAAT/enhancer-binding proteins α and β negatively influence the capacity of tumor necrosis factor α to upregulate the human cytomegalovirus IE1/2 enhancer/promoter by nuclear factor kB during monocyte differentiation. J. Biol. Chem. 276 (2001) 40712-20 Raftery MJ, Schwab M, Eibert SM, Samstag Y, Walczak H, Schönrich G: Targeting the function of mature dendritic cells by Human Cytomegalovirus: A multilayered viral defense strategy. Immunity 15 (2001) 997-1009

Rüdiger M, Köpke U, Prösch S, Rauprich P, Wauer RR, Hertwig E: Effects of perfluorocarbons and perfluorocarbons/surfactant emulsion on growth and viability of group B streptococci and Escherichia coli. Crit. Care Med. 29 (2001) 1786-91


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Schütt M, Gerke P, Meisel H, Ulrich R, Krüger DH: Clinical characterization of Dobrava hantavirus infections in Germany. Clin. Nephrol. 55 (2001) 371-4 Sibold C, Ulrich R, Labuda M, Lundkvist Å, Martens H, Schütt M, Gerke P, Leitmeyer K, Meisel H, Krüger DH: Dobrava hantavirus causes hemorrhagic fever with renal syndrome (HFRS) in central Europe and is carried by two different Apodemus mice species. J. Med. Virol. 63 (2001) 158-67. Thierfelder W, Meisel H, Schreiber E, Dortschy R, Hellenbrand W: Prevalence of markers for hepatitis A, B and C in the German population. Results of the German National Health Interview and Examination Survey 1998. Eur. J. Epidemiol. 17 (2001) 429-35


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2000 Baranyi U, Klein R, Lubitz W, Krüger DH, Witte A: The archaeal halophilic virus-encoded Dam-like methyltransferase, M.Ch1-I, methylates adenine residues and complements dam mutants in the low salt environment of Escherichia coli. Molec. Microbiol. 35 (2000) 1168-79 Dengler TJ., Raftery MJ., Werle M, Zimmermann R, Schönrich G: Cytomegalovirus infection of vascular cells induces expression of pro-inflammatory adhesion molecules by paracrine action of secreted interleukin-1beta. Transplantation 69 (2000) 1160-8 Gedvilaite A, Frömmel C, Sasnauskas K, Micheel B, Özel M, Behrsing O, Staniulis J, Jandrig B, Scherneck S, Ulrich R: Formation of immunogenic virus-like particles by inserting epitopes into surface-exposed regions of Hamster Polyomavirus major capsid protein. Virology 273 (2000) 21-35 Genvresse I, Späth-Schwalbe E, Meisel H, Kaufmann O, Krüger DH, Possinger K: Primary hepatic or splenic diffuse large B-cell lymphoma and hepatitis C virus infection: a non-fortuitous association? Ann. Hematol. 79 (2000) 530-2 Hassen Siray, Frömmel C, Voronkova T, Hahn S, Arnold W, Schneider-Mergener J, Scherneck S, Ulrich R: An immunodominant, cross-reactive B-cell epitope region is located at the C-terminal part of the Hamster Polymavirus major capsid protein VP1. Viral Immunol. 13 (2000) 533-45 Kern F, Faulhaber N, Frömmel C, Khatamzas E, Prösch S, Schönemann C, Kretzschmar I, Volkmer-Engert R, Volk HD, Reinke P: Analysis of CD8 T cell reactivity to cytomegalovirus using protein-spanning pools of overlapping pentadekapeptides. Eur. J. Immunol. 30 (2000) 1676-82 Koletzki D, Lundkvist Å, Brus Sjölander K, Gelderblom HR, Niedrig M, Meisel H, Krüger DH, Ulrich R: Puumala hantavirus strain differences and insertion positions in the hepatitis B virus core antigen influence B-cell immunogenicity and protective potential of core-derived particles. Virology 276 (2000) 364-75 Koletzki D, Schirmbeck R, Lundkvist Å, Meisel H, Krüger DH, Ulrich R: DNA vaccination of mice with a plasmid encoding Puumala hantavirus nucleocapsid protein mimics the B-cell response induced by virus infection. J. Biotechnol. 84 (2000) 73-8 Krüger DH, Schneck P, Gelderblom HR: Helmut Ruska and the visualisation of viruses. Lancet 355 (2000) 1713-7

Mücke M, Lurz R, Mackeldanz P, Behlke J, Krüger DH, Reuter M: Imaging DNA loops induced by restriction endonuclease EcoRII: A single amino acid substitution uncouples DNA target recognition from cooperative DNA interaction and cleavage. J. Biol. Chem. 275 (2000) 30631-7


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Platzer C, Döcke WD, Volk HD, Prösch S: Catecholamines trigger IL-10 release in acute systemic stress reaction by direct stimulation on its promoter/enhancer activity in monocytic cells. J. Neuroimmunol. 105 (2000) 31-8 Preikschat P, Kazaks A, Dishlers A, Pumpens P, Krüger DH, Meisel H: Interaction of wild-type and naturally occurring deleted variants of hepatitis B virus core polypeptides leads to formation of mosaic particles. FEBS Lett. 478 (2000) 127-32 Prösch S, Reinke P, Volk HD, Krüger DH: Cytomegalievirus-Infektionen bei Patienten nach Organtransplantation. Internist 41 (2000) 1253-62 Prösch S, Wendt CEC, Reinke P, Priemer C, Oppert M, Krüger DH, Volk HD, Döcke WD: A novel link between stress and human cytomegalovirus (HCMV) infection: sympathetic hyperactivity stimulates HCMV activation. Virology 272 (2000) 357-65 Raftery MJ, Müller A, Schönrich G: Herpesvirus homologues of cellular genes. Virus Genes 21 (2000) 65-75 Riese U, Brenner S, Döcke WD, Prösch S, Reinke P, Oppert M, Volk HD, Platzer C: Catecholamines induce IL-10 release in patients suffering from acute myocardial infarction by transactivating its promoter in monocytic but not in T-cells. Mol. Cell. Biochem. 212 (2000) 45-50 Ritter T, Brandt C, Prösch S, Vergopoulos A, Vogt K, Kolls J, Volk HD: Stimulatory effect and inhibitory action of cytokines on the regulation of hCMV-IE promoter activity in human endothelial cells. Cytokine 12 (2000) 1163-70 Ruscher K, Reuter M, Kupper D, Trendelenburg G, Dirnagl U, Meisel A: A fluorescence based non-radioactive electrophoretic mobility shift assay. J. Biotechnol. 78 (2000) 163-70 Sobotta D, Sominskaya I, Jansons J, Meisel H, Schmitt S, Heermann KH, Kaluza G, Pumpens P, Gerlich WH: Mapping of immunodominant B-cell epitopes and the human serum albumin-binding site in natural hepatitis B virus surface antigen of defined genosubtype. J. Gen. Virol. 81 (2000) 369-78 Weyer C, Sabat R, Wissel H, Krüger DH, Stevens PA, Prösch S: Surfactant protein A binding to cytomegalovirus proteins enhances virus entry into rat lung cells. Am. J. Respir. Cell Mol. Biol. 23 (2000) 71-8


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1999 Asadullah K, Prösch S, Audring H, Büttnerova I, Volk HD, Sterry W, Döcke WD: A high prevalence of cytomegalovirus antigenaemia in patients with moderate to severe chronic plaque psoriasis: an association with systemic tumour necrosis factor overexpression. Brit. J. Dermatol. 141 (1999) 94-102 Briedigkeit L, Müller-Plathe O, Schlebusch H, Ziems J: Recommendations of the German Working Group on Medical Laboratory Testing (AML) on the introduction and quality assurance of procedures for Point-of-Care Testing (POCT) in hospitals. Clin. Chem. Lab. Med. (formerly: Eur. J. Clin. Chem. Clin. Biochem.) 37 (1999) 919-25 Koletzki D, Biel SS, Meisel H, Nugel E, Gelderblom HR, Krüger DH, Ulrich R: HBV core particles allow the insertion and surface exposure of the entire potentially protective region of Puumala hantavirus nucleocapsid protein. Biol. Chem. 380 (1999) 325-33 Krüger DH, Ulrich R, Gerlich WH: Chimeric virus-like particles as vaccines. Biol. Chem. 380 (1999) 275-6 Kupper D, Möncke-Buchner E, Reuter M, Krüger DH: Oligonucleotide stimulators allow complete cleavage of agarose-embedded DNA by particular type II restriction endonucleases. Anal. Biochem. 272 (1999) 275-7 Lachmann S, Meisel H, Muselmann C, Koletzki D, Gelderblom HR, Borisova G, Krüger DH, Pumpens P, Ulrich R: Characterization of potential insertion sites in the core antigen of hepatitis B virus by the use of a short-sized model epitope. Intervirology 42 (1999) 51-6 Meisel H, Preikschat P, Reinke P, Hocher B, Budde C, Bechstein WO, Neuhaus P, Krüger DH, Neumayer HH: Disappearance of hepatitis B virus core deletion mutants and successful combined kidney/ liver transplantation in a patient treated with lamivudine. Transplant. Int. 12 (1999) 283-7 Meisel H, Reip A, Krüger DH, Budde K, Fritsche L, Neumayer HH: Long-term investigation of hepatitis G virus infection in renal transplant recipients with and without hepatitis B and C co-infection. Transplant. Proc. 31 (1999) 1382-3 Müller-Plathe O, Briedigkeit L, Schlebusch H, Ziems J: Patientennahe Laboratoriumsdiagnostik (Point-of-Care Testing). II. Rechtliche Aspekte. J. Lab. Med. 23 (1999) 600-3 Platzer C, Fritsch E, Elsner T, Lehmann MH, Volk HD, Prösch S: Cyclic adenosine monophosphate-responsive elements are involved in the transcriptional activation of the human IL-10 gene in monocytic cells. Eur. J. Immunol. 29 (1999) 3098-104 Preikschat P, Borisova G, Borschukova O, Dislers A, Mezule G, Grens E, Krüger DH, Pumpens P, Meisel H: Expression, assembly competence and antigenic properties of hepatitis B virus core gene deletion variants from infected liver cells. J. Gen. Virol. 80 (1999) 1777-78


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Preikschat P, Meisel H, Will H, Günther S: Hepatitis B virus genomes from long-term immunosuppressed virus carriers are modified by specific mutations in several regions. J. Gen. Virol. 80 (1999) 2685-91 Prösch S, Döcke WD, Reinke P, Volk HD, Krüger DH: Human cytomegalovirus reactivation in bone marrow-derived granulocyte/monocyte progenitor cells and mature monocytes. Intervirology 42 (1999) 308-13 Reinke P, Prösch S, Kern F, Volk HD: Mechanisms of human cytomegalovirus (HCMV) (re)activation and its impact on organ transplant patients. Transplant Infect. Dis. 1 (1999) 157-64 Reuter M, Schneider-Mergener J, Kupper D, Meisel A, Mackeldanz P, Krüger DH, Schroeder C: Regions of endonuclease EcoRII involved in DNA target recognition identified by membrane-bound peptide repertoires. J. Biol. Chem. 274 (1999) 5213-21 Sasnauskas K, Buzaite O, Vogel F, Jandrig B, Razanskas R, Staniulis J, Scherneck S, Krüger DH, Ulrich R: Yeast cells allow high-level expression and assembly of polyomavirus-like particles. Biol. Chem. 380 (1999) 381-6 Schroter B, Chaoui R, Meisel H, Bollmann R: Maternal hepatitis B infection as the cause of nonimmunologic hydrops fetalis. Z. Geburtshilfe Neonatol. 203 (1999) 36-8 Sibold C, Meisel H, Krüger DH, Labuda M, Lysy J, Kozuch O, Pejcoch M, Vaheri A, Plyusnin A: Recombination in Tula hantavirus evolution: Analysis of genetic lineages from Slovakia. J. Virol. 73 (1999) 667-75 Sibold C, Meisel H, Lundkvist Å, Schulz A, Cifire F, Ulrich R, Kozuch O, Labuda M, Krüger DH: Simultaneous occurrence of Dobrava, Puumala and Tula hantaviruses in Slovakia. Am. J. Trop. Med. Hyg. 61 (1999) 409-11 Siray H, Özel M, Jandrig B, Voronkova T, Jia W, Zocher R, Arnold W, Scherneck S, Krüger DH, Ulrich R: Capsid protein encoding genes of hamster polyomavirus and properties of the viral capsid. Virus Genes 18 (1999) 39-47 Thierfelder W, Meisel H, Schreier E, Dortschy R: Die Prävalenz von Antikörpern gegen Hepatitis-A-, Hepatitis-B- und Hepatitis-C-Viren in der deutschen Bevölkerung. Gesundheitswesen 61 (1999) S110-4 Ulrich R, Koletzki D, Lachmann S, Lundkvist Å, Zankl A, Kazaks A, Kurth A, Gelderblom HR, Borisova G, Meisel H, Krüger DH: New chimaeric hepatitis B virus core particles carrying hantavirus (serotype Puumala) epitopes: Immunogenicity and protection against virus challenge. J. Biotechnol. 73 (1999) 141-53 Zibert A, Kraas W, Ross RS, Meisel H, Lechner S, Jung G, Roggendorf M: Immunodominant B-cell domains of hepatitis C virus envelope proteins E1 and E2 identified during early and late time points of infection. J. Hepatol. 30 (1999) 177-84


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1998 Günther S, Paulij W, Meisel H, Will H: Analysis of hepatitis B virus populations in an Interferon--treated patient reveals predominant mutations in the C-gene and changing e-antigenicity. Virology 244 (1998) 146-60 Hassen Siray, Özel M, Jandrig B, Voronkova T, Jia W, Zocher R, Arnold W, Scherneck S, Krüger DH, Ulrich R: Capsid-protein encoding genes of hamster polyomavirus and properties of the viral capsid. Virus Genes 18 (1998) 39-47 Kunz A, Mackeldanz P, Mücke M, Meisel A, Reuter M, Schroeder C, Krüger DH: Mutual activation of two restriction endonucleases: Interaction of EcoP1 and EcoP15. Biol. Chem. 379 (1998) 617-20 Kunz A, Meisel A, Mackeldanz P, Reuter M, Krüger DH: An experimental selection system to identify bacterial cells exhibiting a new DNA host specificity. Biol. Chem. 379 (1998) 563-6 Lechner S, Rispeter K, Meisel H, Kraas W, Jung G, Roggendorf M, Zibert A: Antibodies directed to envelope proteins of hepatitis C virus outside of hypervariable region 1. Virology 243 (1998) 313-21 Meisel H, Lundkvist A, Gantzer K, Bär W, Sibold C, Krüger DH: First clinical case of infection by hantavirus Dobrava in Germany. Eur. J. Clin. Microbiol. Infect. Dis. 17 (1998) 884-5 Prösch S, Schielke E, Reip A, Meisel H, Volk HD, Einhäupl KM, Krüger DH: Human cytomegalovirus encephalitis in an immunocompetent young person and diagnostic reliability of HCMV-DNA PCR in cerebrospinal fluid of non-immunosuppressed patients. J. Clin. Microbiol. 36 (1998) 3636-40 Reuter M, Kupper D, Meisel A, Schroeder C, Krüger DH: Cooperative binding properties of restriction endonuclease EcoRII with DNA recognition sites. J. Biol. Chem. 273 (1998) 8294-300 Ulrich R, Lundkvist A, Meisel H, Koletzki D, Brus Sjölander K, Gelderblom HR, Borisova G, Schnitzler P, Darai G, Krüger DH: Chimaeric HBV core particles carrying a defined segment of Puumala hantavirus nucleocapsid protein evoke protective immunity in an animal model. Vaccine 16 (1998) 272-80 Ulrich R, Nassal M, Meisel H, Krüger DH: Core particles of hepatitis B virus as carrier for foreign epitopes. Adv. Virus Res. 50 (1998) 141-82


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1997 Back T, Stoltenburg-Didinger G, Ploner CJ, Meisel H, Zschenderlein R: A new variant of progressive encephalomyelitis with rigidity associated with cerebellar ataxia and dementia: Correlation of MRI and histopathological changes. A case report. Neurol Res 19 (1997) 187-91 Heider H, Schroeder C: Focus luminescence assay: macroscopically visualized foci of human cytomegalovirus and varicella zoster virus infection. J Virol Meth 66 (1997) 311-6 Koletzki D, Zankl A, Gelderblom HR, Meisel H, Dislers A, Borisova G, Pumpens P, Krüger DH, Ulrich R: Mosaic hepatitis B virus core particles allow insertion of extended foreign protein segments. J Gen Virol 78 (1997) 2049-53 Kupper D, Reuter M, Meisel A, Krüger DH: Reliable detection of DNA CpG methylation profiles by the isoschizomers MspI / HpaII using oligonucleotide stimulators. BioTechniques 23 (1997) 843-7 Lin T, Heider H, Schroeder C: Different modes of inhibition by adamantane amine derivatives and natural polyamines of the functionally reconstituted influenza virus M2 proton channel protein. J Gen Virol 78 (1997) 767-74 Meisel H, Krüger DH: Gefahr durch Nagetiere: Hantavirus-Infektionen des Menschen. Z Allg Med 73 (1997) 628-35 Prösch S, Pioch K, Stein J, Priemer C, Döcke WD, Ewert R, Volk HD, Reinke P, Krüger DH: Pentoxifylline mediates activation of Human Cytomegalovirus in immunosuppressed patients despite reducing TNF-alpha titers. Biotest Bull 5 (1997) 313-7 Reinke P, Baginski S, Günther S, Krüger DH, Will H, Meisel H: Association between the accumulation of hepatitis B virus core gene deletion mutants and progression of liver disease in long-term renal transplant patients. Transplant Proc 29 (1997) 815-6 Staak K, Prösch S, Stein J, Priemer C, Ewert R, Döcke WD, Krüger DH, Volk HD, Reinke P: Pentoxifylline promotes replication of human cytomegalovirus in vivo and in vitro. Blood 89 (1997) 3682-90

Viazov S, Riffelmann M, Sarr S, Ballauff A, Meisel H, Roggendorf M: Transmission of GBV-C/HGV from drug-addicted mothers to their babies. J Hepatol 27 (1997) 85-90


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Witte A, Baranyi U, Klein R, Sulzner M, Cheng Luo, Wanner G, Krüger DH, Lubitz W: Characterization of Natronobacterium magadii phage phiCh1, an unique archaeal phage containing DNA and RNA. Molec Microbiol 23 (1997) 603-16 Zibert A, Kraas W, Meisel H, Jung G, Roggendorf M: Epitope mapping of antibodies directed against hypervariable region 1 in acute self-limiting and chronic infections due to hepatitis C virus. J Virol 71 (1997) 4123-7 Zibert A, Meisel H, Kraas W, Schulz A, Jung G, Roggendorf M: Early antibody response against hypervariable region 1 is associated with acute self-limiting infections of hepatitis C virus. Hepatology 25 (1997) 1245-9


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1996 Baginski S, Günther S, Reinke P, Krüger DH, Will H, Meisel H: The use of polymerase chain reaction (PCR) in the detection and characterization of HBV variants (letter). Experientia 52 (1996) 291 Gerlich WH, Krüger DH, Ulrich R: Chimeric virus-like particles as vaccines. Editorial. Intervirology 39 (1996) 7-8 Günther S, Baginski S, Kissel H, Reinke P, Krüger DH, Will H, Meisel H: Accumulation and persistence of hepatitis B virus core gene deletion mutants in renal transplant patients are associated with endstage liver cirrhosis. Hepatology 24 (1996) 751-8

Günther S, Piwon N, Iwanska A, Schilling R, Meisel H, Will H: Type, prevalence, and significance of core promoter/enhancer II mutations in hepatitis B viruses from immunosuppressed patients with severe liver disease. J. Virol. 70 (1996) 8318-31 Maerz H, Hahn SO, Maassen A, Meisel H, Roggenbuch D, Sato T, Tanzmann H, Emmrich F, Marx U: Improved removal of virus-like particles from purified monoclonal antibody IgM preparation via virus filtration. Nature Biotechnol. 14 (1996) 651-2

Prösch S, Schielke E, Meisel H, Einhäupl KM, Krüger DH: Diagnostic value of human cytomegalovirus DNA-PCR regarding different clinical specimens (letter). Experientia 52 (1996) 304-5 Prösch S, Stein J, Staak K, Liebenthal C, Volk HD, Krüger DH: Inactivation of the very strong HCMV Immediate Early promoter by DNA CpG methylation in vitro. Biol. Chem. Hoppe-Seyler 377 (1996) 195-201 Roggendorf M, Lu M, Meisel H, Riffelmann M, Schreier E, Viazov S: Rational use of diagnostic tools in hepatitis C. J. Hepatol. 24 (1996) Suppl. 2, 26-34


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Six years after the introduction of serological tests for the detection of antibodies to HCV these diagnostic procedures have been improved significantly. The ELISA's of the third generation contain 4-5 fragments of structural and nonstructural proteins which have increased the sensitivity and specificity for antibody detection. Several confirmatory assays have been established to detect non-specific reactions. Viremia in acute and chronic HCV infection can be detected by RT-PCR. However, studies on the quality of PCR results with serum panels in a large number of diagnostic labs indicate the urgent need to standardize the RT-PCR techniques. Quantification of viral genomes during acute and chronic HCV infection seem to be of major importance to predict the response rat to IFN. Quantitative RT-PCR techniques using internal standards and the branched DNA technology have been established. Techniques for genotyping HCV isolates have been introduced which also seemed to be important for prediction of IFN response. Recently serotyping of HCV isolates has been evaluated and seems to correlate well with genotyping by RT-PCI and specific probes. The detection of quasispecies in the 5'NCR may, in the future, be an additional prospective test for the prognosis of IFN treatment.

Sibold C, Sparr S, Labuda M, Krüger DH, Meisel H: Detection of hantavirus by polymerase chain reaction (letter). Experientia 52 (1996) 309-10 Ulrich R, Gerlich WH, Krüger DH: Chimaera and its modern virus-like descendants. Intervirology 39 (1996) 126-32 Ulrich R, Sommerfeld K, Schröder A, Prokoph H, Arnold W, Krüger DH, Scherneck S: Hamster polyomavirus-encoded proteins: Gene cloning, heterologous expression and immunoreactivity. Virus Genes 12 (1996) 265-74


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1995 Günther S, Bi-Chen L, Miska S, Krüger DH, Meisel H, Will H: A novel method for efficient amplification of whole Hepatitis B Virus genomes permits rapid functional analysis and reveals deletion mutants in immunosuppressed patients. J. Virol. 69 (1995) 5437-44 Krüger DH, Kupper D, Meisel A, Reuter M, Schroeder C: The significance of distance and orientation of restriction endonuclease recognition sites in viral genomes. FEMS Microbiol. Reviews 17 (1995) 177-84

Studies on phage T3 and T7 have shown that these viruses avoid restriction not only by the phage-coded Ocr (and S-adenosylmethionine hydrolase) protein functions or by the complete loss of specific recognition sites for certain restriction endonucleases from their genomes, but also that there are two additional modes: resistance towards EcoP15 (which recognizes a non-symmetrical sequence) is achieved by an identical orientation of all the recognition sites in the virus genome (strand bias) and in the case of EcoRII by the extreme reduction in number and thereby greater distance between recognition sites in the genome. These observations led to the discovery that certain restriction endonucleases require the simultaneous cooperation with two DNA sites for their function, as well as to the ongoing elucidation of the molecular modes of action of these enzymes. Type II and type III enzymes display fundamentally different mechanisms of protein—DNA interaction. For EcoRII we favor a model of simultaneous binding of two DNA sites to a dimeric enzyme molecule (neighbouring sites of the same, looping, DNA molecule or sites located on different DNA molecules), while the action of EcoP15 seems to conform with a tracking-collision model of two enzyme molecules bound to inversely oriented recognition sites. In addition to podoviruses T3 and T7, strand bias of recognition sequences for different type III DNA modification—restriction enzymes is also observed in the inoviruses M13, IKE, and PF3.

Krüger DH, Kupper D, Meisel A, Tierlich M, Reuter M, Schroeder C: Restriction endonucleases functionally interacting with two DNA sites (letter). Gene 157 (1995) 165-6 Kupper D, Reuter M, Krüger DH: Overproduction of His-tagged EcoRII restriction endonuclease and terminally deleted mutant proteins (letter). Gene 157 (1995) 97-8 Kupper D, Reuter M, Mackeldanz P, Meisel A, Alves J, Schroeder C, Krüger DH: Hyperexpressed EcoRII renatured from inclusion bodies and native enzyme both exhibit essential cooperativity with two DNA sites. Protein Expr. Purific. 6 (1995) 1-9 Meisel A, Mackeldanz P, Bickle TA, Krüger DH, Schroeder C: Type III restriction endonucleases translocate DNA in a reaction driven by recognition site-specific ATP hydrolysis. EMBO J. 14 (1995) 2958-66

Meisel H, Reip A, Faltus B, Lu M, Porst H, Wiese M, Roggendorf M, Krüger DH: Transmission of the hepatitis C virus to children and husbands by women infected with contaminated anti-D immunoglobulin. Lancet 345 (1995) 1209-11


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Meisel H, Sominskaya I, Deepen R, Xuangyong L, Spiller GH, Pushko P, Borisova G, Pumpens P, Grens E, Krüger DH, Gerlich WH: Fine-mapping and functional characterization of two immuno-dominant regions from preS2 sequence of hepatitis B virus. Intervirology 37 (1995) 330-9 Ode-Hakim S, Kern F, Fietze E, Prösch S, Ewert R, Nugel H, Volk HD, Reinke P: Association between CMV-related graft injury and circulating cytokine-producing CD8+ memory cells. Transplant. Proc. 27 (1995) 951-3 Prösch S, Staak K, Stein J, Liebenthal C, Stamminger T, Volk HD, Krüger DH: Stimulation of the human cytomegalovirus IE enhancer/promoter in HL-60 cells by TNFa is mediated via induction of NF-kB. Virology 208 (1995) 197-206 Reip A, Haring B, Sibold C, Stohwasser R, Bautz EKF, Darai G, Meisel H, Krüger DH: Coding strategy of the S and M genomic segments of a hantavirus representing a new subgroup of the Puumala serotype. Arch. Virol. 140 (1995) 2011-26 Sibold C, Sparr S, Schulz A, Labuda M, Kozuch O, Lysy J, Krüger DH, Meisel H: Genetic characterization of a new hantavirus detected in Microtus arvalis from Slovakia. Virus Genes 10 (1995) 277-81 Zöller L, Faulde M, Meisel H, Ruh B, Kimming P, Schelling U, Zeier M, Kulzer P, Becker C, Roggendorf M, Bautz EKF, Krüger DH, Darai G: Seroprevalence of hantavirus antibodies in Germany as determined by a novel recombinant enzyme immunoassay. Eur. J. Clin. Microbiol. Infect. Dis. 14 (1995) 305-13


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1994 Döcke WD, Prösch S, Fietze E, Kimel V, Zuckermann H, Klug C, Syrbe U, Krüger DH, von Baehr R, Volk HD: Cytomegalovirus reactivation and tumor necrosis factor. Lancet 343 (1994) 268-9

Döcke WD, Reinke P, Staffa G, Settmacher U, Höger T, Groth J, Lang K, Lock KU, Prösch S, Kimmel V, Warnke H, von Baehr R, Volk HD: An immune monitoring program for the management of immunosuppressive therapy in the early phase after transplantation. Transplantationsmedizin 6 (1994) 13-28 Fietze E, Prösch S, Reinke P, Stein J, Döcke WD, Staffa G, Loening S, Emmrich F, von Baehr R, Krüger DH, Volk HD: Cytomegalovirus infection in transplant recipients: Role of tumor necrosis factor. Transplantation 58 (1994) 675-80 Maaßen A, Rehfeldt A, Kießig S, Ladhoff A, Höhne WE, Meisel H: Comparison of three different recombinant hepatitis B virus core particles expressed in E. coli. Arch. Virol. 135 (1994) 131-42 Prösch S, Schrader-Bechstein U, Witt G, Kimel V, Teterin W, Czschiesnek R, Krüger DH: HCMV strain comparison by restriction analysis of genomic virus DNA and of a PCR-amplified DNA fragment. Clin. Diagn. Virol. 2 (1994) 17-28 Reinke P, Fietze E, Ode-Hakim S, Prösch S, Lippert J, Ewert, R, Volk HD: Late-acute renal allograft rejection and symptomless cytomegalovirus infection. Lancet 344 (1994) 1737-8

Schroeder C, Ford CM, Wharton SA, Hay AJ: Functional reconstitution in lipid vesicles of influenza virus M2 protein expressed by baculovirus: evidence for proton transfer activity. J. Gen. Virol. 75 (1994) 3477-84


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1993 Bickle TA, Krüger DH: Biology of DNA restriction. Microbiol. Reviews 57 (1993) 434-50

Krüger DH, Prösch S, Kimel V, Schultze W, Volk HD: Monitoring immunsupprimierter Patienten auf Cytomegalievirus-Infektion: Bedeutung für die Einleitung und Kontrolle der antiviralen Therapie. Chemother. J. 2 (1993) 63-6 Miska S, Günther S, Vassilev M, Meisel H, Pape G, Will H: Heterogeneity of hepatitis B virus C-gene sequence: Implications for amplification and sequencing. J. Hepatol. 18 (1993) 53-61

Müller R, Baumgarten R, Markus R, Schulz M, Wittenberg H, Hintsche-Kilger B, Fengler HD, von Wussow P, Meisel H, Klein H, Malmus K, Schmidt FW: Low dose alpha interferon treatment in chronic hepatitis B virus infection. Gut 34 (1993) S97-8

Reuter M, Kupper D, Pein CD, Petrusyte M, Siksnys V, Frey B, Krüger DH: Use of specific oligonucleotide duplexes to stimulate cleavage of refractory DNA sites by restriction endonucleases. Anal. Biochem. 209 (1993) 232-7 Siakkou H, Jahn S, Kienzle N, Ulrich R, Grötzinger C, Schneider T, Pauli G, Spohn R, Jung G, Müller-Lantzsch N, Krüger DH: Epitope fine mapping of new Nef-specific monoclonal antibodies of the Human Immunodeficiency Virus 1. Arch. Virol. 128 (1993) 81-95


55

Stein J, Volk HD, Liebenthal C, Krüger DH, Prösch S: Tumor necrosis factor alpha stimulates the activity of the human cytomegalovirus immediate-early enhancer/promoter in immature monocytic cells. J. Gen. Virol. 74 (1993) 2333-8 Ulrich R, Siakkou H, Mayer J, Kienzle N, Müller-Lantzsch N, Krüger DH: Subcloning of HIV-2 nef genes in E. coli and immunological reactivity of expressed fusion proteins. Virus Genes 7 (1993) 229-40


56

1992 Günther S, Meisel H, Reip A, Miska S, Krüger DH, Will H: Frequent and rapid emergence of mutated pre-C sequences in HBV from e-antigen positive carriers who seroconvert to anti-HBe during interferon treatment. Virology 187 (1992) 271-9 Kienzle N, Enders M, Buck M, Siakkou H, Jahn S, Petzold G, Schneweis KE, Bachmann M, Müller WEG, Müller-Lantzsch N: Expression of the HIV-1 Nef protein in the baculovirus system: investigation of anti-Nef antibodies response in human sera and subcellular localization of Nef. Arch. Virol. 126 (1992) 293-301 Klimov AI, Markushin SG, Prösch S, Ginzburg VP, Heider H, Heider AM, Schroeder C, Webster RG: Relation between drug resistance and antigenicity among norakin-resistant mutants of influenza A (Fowl plague) virus. Arch. Virol. 124 (1992) 147-55 Klimov AI, Prösch S, Schäfer J, Bucher D: Subtype H7 influenza viruses: comparative antigenic and molecular analysis of the HA-, M- and NS-genes. Arch. Virol. 122 (1992) 143-61 Mayer J, Kienzle N, Ulrich R, Hunsmann G, Müller-Lantzsch N: High frequency of antibodies against recombinant HIV-2 Nef protein in HIV-2 positive and HIV negative sera. AIDS 6 (1992) 519-20 Meisel A, Bickle TA, Krüger DH, Schroeder C: Type III restriction enzymes need two inversely oriented recognition sites for DNA cleavage. Nature (Lond.) 355 (1992) 467-9

Prösch S, Kimel V, Dawydowa I, Krüger DH: Monitoring of patients for cytomegalovirus after organ transplantation by centrifugation culture and PCR. J. Med. Virol. 38 (1992) 246-51 Repke H, Barber E, Ulbricht S, Buchner K, Hucho F, Kopp R, Scholz D, Rudd CE, Haseltine WA: Ganglioside-induced CD4 endocytosis occurs independent of serine phosphorylation and is accompanied by dissociation of p56-lck. J. Immunol. 149 (1992) 2585-91 Ulrich R, Borisova GP, Gren E, Berzin I, Pumpen R, Eckert V, Ose V, Siakkou H, Gren EJ, von Baehr R, Krüger DH: Immunogenicity of recombinant core particles of hepatitis B virus containing epitopes of human immunodeficiency virus 1 core antigen. Arch. Virol. 126 (1992) 321-8 Ulrich R, Siakkou H, Krüger DH: Expression of HIV-2 Gag and Env antigens in E.coli. Acta Virol. 36 (1992) 491


57

1991 Döcke WD, Simon HU, Fietze E, Prösch S, Diener C, Reinke P, Stein H, Volk HD: Cytomegalovirus infection and common variable immunodeficiency. Lancet 338 (1991) 1597

Gachechiladze KK, Balardshishvili NS, Adamia RS, Chanishvili TG, Krüger DH: Host-controlled modification and restriction as a criterion of evaluating the therapeutical potential of Pseudomonas phage. J. Basic Microbiol. 31 (1991) 101-6 Jahn S, Schwab J, Hansen A, Heider H, Schroeder C, Lukowsky A, Achtman M, Matthes H, Kiessig ST, Volk HD, Krüger DH, von Baehr R: Human hybridomas derived from CD-5-positive B lymphocytes of patients with chronic lymphocytic leukemia (B-CLL) produce multispecific natural IgM (kappa) antibodies. Clin. Exp. Immunol. 83 (1991) 413-7 Markus R, Hintsche B, Baumgarten R, Fengler JD, Meisel H: Zur Behandlung der protahiert verlaufenden akuten Virushepatitis B mit rekombinanten Interferon-alpha-2b. Z. Klin. Med. 46 (1991) 501-3 Matthes E, Reimer K, von Janta-Lipinski M, Meisel H, Lehmann G: Comparative inhibition of hepatitis B virus DNA polymerase and cellular DNA polymerases by triphosphates of sugar-modified 5-methyldeoxycytidines and of other nucleoside analogs. Antimicrob. Agents Chemother. 35 (1991) 1254-7 Meisel A, Krüger DH, Bickle TA: M.EcoP15 methylates the second adenine in the recognition sequence. Nucleic Acids Res. 19 (1991) 3997 Pein CD, Reuter M, Meisel A, Cech D, Krüger DH: Activation of restriction endonuclease EcoRII does not depend on the cleavage of stimulator DNA. Nucleic Acids Res. 19 (1991) 5139-42 Reimer K, von Janta-Lipinski, Matthes E, Meisel H: Inhibition of hepatitis B virus DNA-polymerase by thymidine triphosphate analogs in vitro. Antiviral Chem. Chemother. 2 (1991) 249-53 Reimer K, Meisel H: Über den Zusammenhang von Hepatitis-B-Virusinfektion und hepatozellulärem Karzinom. Z. Ärztl. Fortbildung 85 (1991) 246-51 Schroeder C, Maaßen A, Lippoldt A, Meisel H, Börner T, von Baehr R, Dobrowolski P: Expression of the core antigen gene of hepatitis B virus (HBV) in Acetobacter methanolicus using new broad-host-range vectors. Appl. Microbiol. Biotechnol. 35 (1991) 631-7


58

Ulrich R, Bähring S, Siakkou H, Rosenthal S: Expression of bovine leukemia virus antigens fused to MS2 polymerase in E. coli. Acta Virol. 35 (1991) 391-5 Ulrich R, Borisova GP,Siakkou H, Platzer C, Ose VP, Berzin JG, Dreilina D, Pushko PM, Tsibinogin VV, Pumpen P, Rosenthal HA, Gren EJ: Surface exposure of a major immunodominant epitope of the gp51 coat protein of bovine leukemia virus on capsids consisting of hepatitis B virus core antigen (in Russ.). Molec. Biol. 25 (1991) 301-6 Ulrich R, Petzold G, Möhring R, Lätzsch I, Dittmann S, Rosenthal HA: Rekombinanter Western blot zum Nachweis von Antikörpern gegen das humane Immundefizienzvirus 1. Z. Klin. Med. 46 (1991) 93-5 Ulrich R, Pushko P, Kozlovskaya T, Siakkou H, Pumpen P, Dreilina D, Platzer C: Precise localization of the epitope of major BLV envelope protein. Acta Virol. 35 (1991) 302 Woodcock DM, Crowther PJ, Doherty JP, Linsenmeyer ME, Krüger DH: A sizing artifact of DNA restriction fragments with unusually long single-stranded termini. Gene 102 (1991) 79-81 von Janta-Lipinski M, Gaertner K, Schildt J, Matthes E, Scholz D, Langen P: Synthesis and anti-HIV activity of modified 2’, 3’-Dideoxy-3’-Fluoro Pyrimidine Nucleosides. Nucleosides & Nucleotides 10 (1991) 651-2


59

1990 Baumgarten R, Meisel H, Fengler JD, Markus R, Kaufmann W: Virostaste und Immunstimulation – Behandlungsprinzipien der chronisch-aktiven Hepatitis B. Z. Klin. Med. 45 (1990) 525-8 Dittmann S, Baumgarten R, Dürkop J, Fengler JD, Glatke H, Kiehl W, Markus R, Meisel H, Müller D: Empfehlung zur Erkennung, Verhütung und Bekämpfung der Virushepatitis. Z. Ärztl. Fortbild. 84 (1990) 687-98 Götze W, Jantschak J, Kohls A, Eiling D, Schildhaus I: Nachweis von humanen Papillomvirus-(HPV)-16/18-Infektionen der Portio vaginalis cervicis uteri bei Frauen vor und nach Konisation. Zentralbl. Gynäkol. 112 (1990) 875-81 Krüger DH, Prösch S, Reuter M, Goebel W: Cloning of the resistant EcoRII recognition site of phage T7 into an EcoRII-sensitive plasmid makes the site suceptible to the restriction enzyme. J. Basic Microbiol. 30 (1990) 679-83 Krüger DH, Reuter M, Chernin LS, Gachechiladze KK, Chanishvili TG, Schroeder C: Biologische Funktionen der Restriktionsendonukleasen. Biol. Zentralbl. 109 (1990) 257-66 Ladhoff AM, Takahashi I, Takama M, Scholz D, Rosenthal HA: Die Ultrastruktur des humanen Immuninsuffizienz-Virus (HIV) Typ 1. Z. Klin. Med. 45 (1990) 309-14 Matthes E, Scholz D, Sydow G, von Janta-Lipinski M, Langen M, Rosenthal HA: 3’-fluoro-substituted dioxynucleosides as potential anti-AIDS drugs. Z. Klin. Med. 45 (1990) 1255-8 Meisel H, Reimer K, von Janta-Lipinski M, Bärwolff D, Matthes E: Inhibition of hepatitis B virus DNA polymerase by 3’-fluorothymidine triphosphate and other modified nucleoside triphosphate analogs. J. Med. Virol. 30 (1990) 137-141 Müller R, Baumgarten R, Markus R, Schulz M, Wittenberg H, Hintsche-Kilger B, Fengler JD, von Wussow P, Meisel H, Klein H, Malmus K, Schmidt FW: Behandlung der chronischen Hepatitis B mit Interferon alpha-2b. Dtsch. Med. Wochenschr. 115 (1990) 403-7 Müller R, Baumgarten R, Markus R, Schulz M, Wittenberg H, HIntsche Kilger B, Fengler JD, von Wussow P, Meisel H, Klein H, Malmus K, Schmidt FW: Treatment of chronic hepatitis B with interferon alpha-2b. J. Hepatol. 11 (1990) 137-40

Pein CD, Reuter M, Cech D, Krüger DH: Oligonucleotide duplexes stimulate cleavage of refractory DNA by type II restriction endonucleases. Collect Czech. Chem. Commun. Spec. Iss. 55 (1990) 265-8


60

Platzer C, Siakkou H, Kraus G, Gröbel C, Rosenthal S: Use of a monoclonal antibody against the major internal protein p24 of bovine leukemia virus in a capture ELISA. Arch. Exp. Vet. Med. 44 (1990) 905-8 Platzer C, Siakkou H, Sober J, Kopp J, Scheve E, Rosenthal S: Identification of an immunodominant region on the isolated BLV major envelope protein gp51 by monoclonal antibodies presumably no exposed during natural BLV infection. Acta Virol. 34 (1990) 246-55 Porstmann B, Priem S, Evers U, Scholz D, Porstmann T: Eine neue Protein-Färbemethode auf Nitrocellulose – die enzymatische Proteinfärbung. J. Clin. Chem. Clin. Biochem. 28 (1990) 772 Prösch S: Characterization of a RD114-related endogenous cat retroviral element ECE2. Arch. Exp. Vet. Med. 44 (1990) 909-14 Prösch S, Heider H, Schroeder C, Shilov AA, Sinitzyn BV, Blinov VM, Krüger DH, Frömmel C: Mapping mutations in influenza A virus resistant to norakin. FEBS Lett. 267 (1990) 19-21 Reuter M, Pein CD, Butkus V, Krüger DH: An improved method for the detection of Dcm methylation in DNA molecules. Gene 95 (1990) 161-2 Siakkou H, Kube D, Peters H, Otto A, Ulrich R, Rosenthal S: New ELISA test for the detection of bovine leukemia virus infections in cattle using bacterially synthesized p24. Arch. Exp. Vet. Med. 44 (1990) 899-904 Siakkou H, Platzer H, Beier D, Olechnowitz AF, Rosenthal S: Verwendung eines monoklonalen Antikörpers gegen das Hüllprotein gp51 des bovinen Leukämievirus in einem Test zur Diagnose der enzootischen Rinderleukose. Arch. Exp. Vet. Med.. 44 (1990) 223-32 Siakkou H, Ulrich R, Uelze A, Möhring R, Rosenthal S: Immunological characterization of BLV proteins synthesized in Escherichia coli. Acta Virol. 34 (1990) 256-62 Ulrich R, Borisova GP, Möhring R, Lätzsch I, Ose VP, Berzin IG, Dreilina DE, Pushko PM, Tsibonogin VV, Pumpen PP, Rosenthal HA, Gren EJ: Exposition von Epitopen des HIV-Transmembranproteins gp41 auf der Kapsidoberfläche des Hepatitis-B-Core-Antigens (in Russ.). Bioorgan. Khimiya 16 (1990) 1283-5 Ulrich R, Siakkou H, Platzer C, Bossmann H, Wiedmann M, Möhring R, Rosenthal S: Synthesis of BLV antigens in Escherichia coli. Arch. Exp. Vet. Med. 44 (1990) 883-90

Publikationen 1990 bis 2015 Buchbeiträge

61

Buchbeiträge

2015 Krüger DH: Hantavirus-Krankheiten. In: Handbuch der Infektionskrankheiten (Hofmann F, Hrg), 63. Ergänzungslieferung. Ecomed Medizin-Verlag, Landsberg am Lech, 2015, S. 1-12 Krüger DH, Oehme P, Scheler W: Friedrich Jung – seine Beziehung zu Helmut Ruska und zur Virologie. In: Sitzungsberichte der Leibniz-Sozietät der Wissenschaften, Band 123/124 (Hrg: Gross J, Jacobasch G, Oehme P). trafo-Wissenschaftsverlag, Berlin, 2015, S. 45-53 Matsumura H, Krüger DH, Kahl G, Terauchi R: SuperSAGE as an analytical tool for host and viral gene expression. In: Plant Virology Protocols (Uyeda I, Masuta C, eds.). Methods in Molecular Biology, Vol. 1236. Springer Science+Business Media, New York, 2015, pp. 181-95

2014 Schlegel M, Jacob J, Krüger DH, Rang A, Ulrich RG: Hantavirus emergence in rodents, insectivores and bats: What comes next? In: The Role of Animals in Emerging Viral Diseases (Johnson N, ed.). Academic Press/ Elsevier, Amsterdam – Boston – Heidelberg 2014, pp. 235-92

2013 Krüger DH, Beetz R, Panning M: Hantavirus-Infektionen. In: DGPI-Handbuch (Deutsche Gesellschaft für Pädiatrische Infektiologie); Berner R et al (Hrg), 6.vollst. überarbeitete Auflage. Georg Thieme Verlag, Stuttgart – New York, 2013, S. 284-8 Voigt S, Ettinger J, Streblow DN: The rat model of cytomegalovirus infection and vascular disease. In: Cytomegaloviruses: From Molecular Pathogenesis to Therapy, Vol. 2 (M.J. Reddehase, ed.) Caister Academic Press, Norfolk (UK), 2013, p. 312-36 Wade G, Bogner E: Morphogenesis of the cytomegalovirus virion and subviral particles. In: Cytomegaloviruses: From Molecular Pathogenesis to Intervention, Vol. 1 (M.J. Reddehase, ed.). Caister Academic Press, Norfolk (UK), 2013, p. 230-46

2012 Fischer SF, Al Dahouk S, Brandt C, Donoso-Mantke O, Frangoulidis D, Hofmann J, Jansen A, Krüger DH, Kimmig P, Kurth A, Niedrig M, Nitsche A, Nöckler K, Roggendorf M, Roß RS, Schacht E, Mayer-Scholl A, Scholz HC, Splettstoesser WD, Stark K,Wagner-Wiening C, Zöller L, Kempf VAJ: Zoonosen. Mikrobiologisch-infektiologische Qualitätsstandards (MiQ), Band 33 (Podbielski A et al., Serien-Editoren). Elsevier Urban & Fischer, München 2012, 108 Seiten


62

Jilg W, Meisel H, Krüger DH: Hepatitis-B-Virus (HBV). In: Lexikon der Infektionskrankheiten des Menschen, 4. Auflage (Darai G et al., Hrg.). Springer, Heidelberg-New York, 2012, S. 371-7 Jilg W, Meisel H, Krüger DH: Hepatitis-D-Virus (HDV). In: Lexikon der Infektionskrankheiten des Menschen, 4. Auflage (Darai G et al., Hrg.). Springer, Heidelberg-New York, 2012, S. 382-6 Matsumura H, Molina C, Kruger DH, Terauchi R, Kahl G: DeepSuperSAGE: High-throughput transcriptome sequencing with now- and next-generation sequencing technologies. In: Tag-based Next Generation Sequencing (Harbers M, Kahl G, eds.). Wiley-VCH Verlag, Weinheim, 2012, pp. 3-21 Matsumura H, Urasaki N, Yoshida K, Krüger DH, Kahl G, Terauchi R: SuperSAGE: powerful serial analysis of gene expression. In: RNA Abundance Analysis: Methods and Protocols (Jin H, Grossmann W, eds.). Methods in Molecular Biology, Vol. 883, Springer, New York 2012, pp. 1-17 Meisel H, Jilg W, Krüger DH: GB-Virus (GBV-C). In: Lexikon der Infektionskrankheiten des Menschen, 4. Auflage (Darai G et al., Hrg.). Springer, Heidelberg-New York, 2012, S. 332-4 Meisel H, Jilg W, Krüger DH: Hepatitis-C-Virus (HCV). In: Lexikon der Infektionskrankheiten des Menschen, 4. Auflage (Darai G et al., Hrg.). Springer, Heidelberg-New York, 2012, S. 377-82 Schönrich G: Dengueviren. In: Lexikon der Infektionskrankheiten des Menschen, 4. Auflage (Darai G et al., Hrg). Springer, Heidelberg-New York, 2012, S. 230-4 Schönrich G: Seltene humanpathogene Flaviviren. In: Lexikon der Infektionskrankheiten des Menschen, 4. Auflage (Darai G et al., Hrg). Springer, Heidelberg-New York, 2012, S. 305-11 Schönrich G: Frühsommer-Meningoenzephalitis und Russische Frühjahrs-Sommer-Enzephalitis. In: Lexikon der Infektionskrankheiten des Menschen, 4. Auflage (Darai G et al., Hrg). Springer, Heidelberg-New York, 2012, S. 316-20 Schönrich G: Gelbfiebervirus. In: Lexikon der Infektionskrankheiten des Menschen, 4. Auflage (Darai G et al., Hrg). Springer, Heidelberg-New York, 2012, S. 334-8 Schönrich G: Japanisches Enzephalitisvirus. In: Lexikon der Infektionskrankheiten des Menschen, 4. Auflage (Darai G et al., Hrg). Springer, Heidelberg-New York, 2012, S. 455-8 Schönrich G: West-Nil-Virus. In: Lexikon der Infektionskrankheiten des Menschen, 4. Auflage (Darai G et al., Hrg). Springer, Heidelberg-New York, 2012, S. 938-42


63

2011 Krüger DH, Klempa B: Dobrava-Belgrade virus. In: Molecular Detection of Human Viral Pathogens (Liu D, ed). CRC Press, Boca Raton-London-New York, 2011, pp 631-8 Matsumura H, Yoshida K, Luo S, Krüger DH, Kahl G, Schroth GP, Terauchi R: High-throughput SuperSAGE. In: Methods in Molecular Biology (Park DJ, ed), Vol. 687. Humana Press, 2011, pp 135-46

2010 Krüger DH: Hantavirus-Erkrankungen. In: Handbuch der Infektionskrankheiten (Hofmann F, ed), Kapitel VIII-6.16, 38. Ergänzungslieferung 11/10, Ecomed-Verlag, Landsberg, 2010, S. 1-11. Matsumura H, Yoshida K, Luo S, Krüger DH, Kahl G, Schroth GP, Terauchi R: High-throughput SuperSAGE. In: Park DJ (ed.), PCR Protocols, Methods in Molecular Biology, Vol. 687, Springer Publ., New York 2010, pp 135-46.

2009 Bitzan M, Ehrich JHH, Krüger DH, Schmitz H: Hantavirus-Infektionen. In: Deutsche Gesellschaft für pädiatrische Infektiologie (Hrg.), Handbuch Infektionen bei Kindern und Jugendlichen, 5. Auflage. Georg Thieme Verlag, Stuttgart - New York, 2009, S. 264-8 Kaspari M, Bogner E: Antiviral activity of proteasome inhibitors / Cytomegalovirus. In: Lendeckel U, Hopper N (Hrg.), Viral Proteases and Antiviral Protease Inhibitor Therapy. Springer, New York - Dodrecht, 2009, S. 71-81 Krüger DH: Hantaviren. In: Doerr HW, Gerlich W (Hrg.), Medizinische Virologie, 2. Auflage. Georg Thieme Verlag, Stuttgart - New York, 2009, S. 580-8 Krüger DH: Bunyaviren: Hantaviren. In: Neumeister B et al (Hrg.), Burkhardt - Mikrobiologische Diagnostik, 2. Auflage. Georg Thieme Verlag, Stuttgart - New York, 2009, S. 953-8 Meisel H: Hepatitis E. In: Neumeister B et al. (Hrg.), Burkhardt – Mikrobiologische Diagnostik, 2. Auflage. Georg Thieme Verlag, Stuttgart-New-York, 2009, S. 856-61

2008 Matsumura H, Reuter M, Krüger DH, Winter P, Kahl G, Terauchi R: SuperSAGE. In: Nielsen KL (ed.), Serial Analysis of Gene Expression: Digital Gene Expression Profiling (Methods in Molecular Biology, Vol. 387). Humana Press Inc., Totowa, NJ, 2008, pp 55-70


64

Meisel H, Krüger DH: GB Virus C. In: Darai G, Handermann M, Sonntag HG, Tidona CA, Zöller L (Hrg), Lexikon der Infektionskrankheiten des Menschen, 3. Auflage. Springer, Berlin-Heidelberg-New York, 2008, S. 334-6 Meisel H, Märschenz S, Krüger DH: Hepatitis B Virus. In: Darai G, Handermann M, Sonntag HG, Tidona CA, Zöller L (Hrg), Lexikon der Infektionskrankheiten des Menschen, 3. Auflage. Springer, Berlin-Heidelberg-New York, 2008, S. 371-6 Meisel H, Märschenz S, Krüger DH: Hepatitis C Virus. In: Darai G, Handermann M, Sonntag HG, Tidona CA, Zöller L (Hrg), Lexikon der Infektionskrankheiten des Menschen, 3. Auflage. Springer, Berlin-Heidelberg-New York, 2008, S. 376-81 Meisel H, Märschenz S, Krüger DH: Hepatitis D Virus. In: Darai G, Handermann M, Sonntag HG, Tidona CA, Zöller L (Hrg), Lexikon der Infektionskrankheiten des Menschen, 3. Auflage. Springer, Berlin-Heidelberg-New York, 2008, S. 381-5 Terauchi R, Matsumura H, Krüger DH, Kahl G: SuperSAGE: The most advanced transcriptome technology for functional genomics. In: Kahl G, Meksem K (eds.), The Handbook of Plant Functional Genomics: Concepts and Protocols. Wiley-VCH Publ., Weinheim 2008, pp. 37-54

2006 Prösch S, Kaspari M: Proteasome inhibitors as complementary or alternative antiviral therapeutics. In: New concepts of antiviral therapies, (Bogner, E. and Holzenburg, A. eds), Springer, New York and Dodrecht, 2006, pp 337-49, ISBN: 0-387-31046-0 Terauchi R, Matsumura H, Ito A, Fujisawa S, Bin Nasir KH, Saitoh H, Kamoun S, Winter P, Kahl G, Reuter M, Krüger DH: SuperSAGE, a potent tool to dissect plant-microbe interactions. In: Sanchez F et al. (eds.), Biology of Plant-Microbe Interactions, Vol. 5, International Society for Molecular Plant-Microbe Interactions, St. Paul, MN, USA, 2006, pp. 569-75, ISBN: 978-0-9654625-4-9

2005 Matsumura H, Reich S, Reuter M, Krüger DH Winter P, Kahl G, Terauchi R: SuperSAGE: A potent transcriptome tool for eukaryotic organisms. In: SAGE – Current Technologies and Applications (Wang SM, ed). Horizon Scientific Press, Wymondham, Norfolk, UK, 2005, pp. 77-90

2004 Krüger DH, Feldmann H: Hantaviren. In: Diagnostik und Therapie von Viruskrankheiten: Leitlinien der Gesellschaft für Virologie. Kompendium für Studierende und Ärzte (Mertens T, Haller O, Klenk HD, Hrg.), 2. überarb. Auflage. Urban & Fischer, Elsevier GmbH, München, 2004, S. 83-8 Reuter M, Mücke M, Krüger DH: Structure and function of Type IIE restriction endonucleases: From a plasmid that restricts phage replication to a new molecular DNA recognition mechanism. In: Restriction Endonucleases (Pingoud A, ed). Springer, Berlin Heidelberg New York 2004, pp 261-95


65

2003 Meisel H, Endres AS, Krüger DH: Hepatitis B Virus. In: Lexikon der Infektionskrankheiten des Menschen (Darai G, Handermann M, Hinz E, Sonntag HG, Hrg.). Springer, Berlin-Heidelberg-New York, 2003, S. 307-15 Meisel H, Endres AS, Krüger DH: Hepatitis C Virus. In: Lexikon der Infektionskrankheiten des Menschen (Darai G, Handermann M, Hinz E, Sonntag HG, Hrg.). Springer, Berlin-Heidelberg-New York, 2003, S. 315-20 Meisel H, Endres AS, Krüger DH: Hepatitis D Virus. In: Lexikon der Infektionskrankheiten des Menschen (Darai G, Handermann M, Hinz E, Sonntag HG, Hrg.). Springer, Berlin-Heidelberg-New York, 2003, S. 320-5 Prösch S, Wuttke R, Krüger DH, Volk HD: New concepts for inhibition of HCMV reactivation and replication. In: New aspects of CMV-related immunopathology (Prösch S, Cinatl J, Scholz M, eds). Monographs in Virology, Vol. 24. Karger, Basel, 2003, pp 182-94. Schönrich G: Dengueviren. In: Lexikon der Infektionskrankheiten des Menschen (Darai G, Handermann M, Hinz E, Sonntag HG, Hrg.). Springer, Berlin-Heidelberg-New York, 2003, S. 179-82 Schönrich G: Frühsommer-Meningoenzephalitis und Russische Frühjahrs-Sommer-Enzephalitis. In: Lexikon der Infektionskrankheiten des Menschen (Darai G, Handermann M, Hinz E, Sonntag HG, Hrg.). Springer, Berlin-Heidelberg-New York, 2003, S. 258-63 Schönrich G: Gelbfiebervirus. In: Lexikon der Infektionskrankheiten des Menschen (Darai G, Handermann M, Hinz E, Sonntag HG, Hrg.). Springer, Berlin-Heidelberg-New York, 2003, S. 276-81 Schönrich G: Japanisches Enzephalitisvirus. In: Lexikon der Infektionskrankheiten des Menschen (Darai G, Handermann M, Hinz E, Sonntag HG, Hrg.). Springer, Berlin-Heidelberg-New York, 2003, S. 361-4 Schönrich G: Seltene humanpathogene Flaviviren. In: Lexikon der Infektionskrankheiten des Menschen (Darai G, Handermann M, Hinz E, Sonntag HG, Hrg.). Springer, Berlin-Heidelberg-New York, 2003, S. 244-51

2002 Meisel H, Endres AS: Der natürliche Verlauf der Hepatitis C. In: Koinfektion Hepatitis und HIV. (Maus S, Rockstroh JK, Jäger H, Hrg). Stuttgart, New York, Thieme, 2002, 22-33 Reuter M, Möncke-Buchner E: Analysis of Protein-DNA interactions. In: Springer Lab Manual 22: Peptide Arrays on Membrane Supports (Koch J, Mahler M, eds.), Springer-Verlag Berlin Heidelberg, 2002, 97-106


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1999 Krüger DH: In: Diagnostik und Therapie von Viruskrankheiten – Leitlinien der Gesellschaft für Virologie (Haller OA, Mertens T, Hrg). Urban & Fischer Verlag, München-Jena, 1999 Krüger DH, Reuter M: Host-controlled modification and restriction. In: Encyclopedia of Virology, 2nd Edition (Webster RG, Granoff A, eds). Academic Press, San Diego-San Francisco-New York-Boston-London-Sydney-Tokyo, 1999, pp 758-63 Krüger DH, Ulrich R, Gerlich HW (eds.): Virus-like Particles as Vaccines. Thematic Issue of Biological Chemistry, Vol. 380, No. 3. Walter de Gruyter, Berlin, 1999 Schroeder C, Heider H: Virostatika. In: Antibiotika im Alter – Antiinfectiva –, 7. Auflage, Media Bibliothek/SMV Edition Materia Medica, Pharmacia & Upjohn, Erlangen, 1999, S. 199-251

1998 Prösch S, Volk HD, Reinke P, Pioch K, Döcke WD, Krüger DH: Human cytomegalovirus infection in transplant recipients: Role of TNF- for reactivation and replication of Human Cytomegalovirus. In: CMV-Related Immunopathology. (Monographs in Virology, Doerr HW ed, Vol. 21). Karger, Basel, 1998, pp 29-41

1997 Ulrich R, Koletzki D, Zankl A, Schulz A, Meisel H, Krüger DH, Gelderblom HR, Dislers A, Borisova G, Pumpens P: A new strategy to generate mosaic HBcAg particles presenting foreign epitopes. In: Vaccines ‘97 (Brown F et al, eds). Cold Spring Harbor Laboratory Press, New York, pp 235-40 Krüger DH, Meisel H: Hepatitis B Virus. In: Lexikon der Infektionskrankheiten des Menschen (Darai G, Handermann M, Hinz E, Sonntag HG, Hrg.). Springer-Verlag, Berlin-Heidelberg-Wien 1997, S. 239-45 Krüger DH, Meisel H: Hepatitis Delta Virus (HDV). In: Lexikon der Infektionskrankheiten des Menschen (Darai G, Handermann M, Hinz E, Sonntag HG, Hrg.). Springer-Verlag, Berlin-Heidelberg-Wien 1997, S. 250-4 Meisel H, Krüger DH: Hepatitis C Virus und GB Virus. In: Lexikon der Infektionskrankheiten des Menschen (Darai G, Handermann M, Hinz E, Sonntag HG, Hrg.). Springer-Verlag, Berlin-Heidelberg-Wien 1997, S. 245-9


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1996 Günther S, Miska S, Meisel H, Will H: Structure and selection of hepatitis B virus variants during the natural course of infection and interferon therapy. In: Proceedings of the 25th International Symposium of the Princess Takamatsu Cancer Research Fund. Princeton Scientific Publishing Co., Inc., Princeton, NJ, USA, 1996, pp. 211-20 Jantschak J, Meisel H: Nachweis viraler Nukleinsäuren durch Hybridisierung. In: Diagnostische Bibliothek Band 1: Virusdiagnostik (Hrg: T. Porstmann). Blackwell-Verlag, Berlin-Wien-Oxford, 1996, S. 31-60 Krüger DH: Weltweite Verbreitung verschiedener Hantaviren. In: Aktuelle Themen der Reisemedizin (Hrg: M. Niedrig, J. L’age-Stehr). Robert-Koch-Institut-Hefte No. 12, Berlin 1996, S. 141-50 Krüger DH, Zöller L: Hantaviren. In: Diagnostische Bibliothek Band 1: Virusdiagnostik (Hrg: T. Porstmann). Blackwell-Verlag, Berlin-Oxford, 1996, S. 117-28 Meisel H: Hepatitis-E-Virus. In: Diagnostische Bibliothek Band 1: Virusdiagnostik (Hrg: T. Porstmann). Blackwell-Verlag, Berlin-Wien-Oxford, 1996, S. 131-42 Meisel H: Hepatitis-C-Virus. In: Diagnostische Bibliothek Band 1: Virusdiagnostik (Hrg: T. Porstmann). Blackwell-Verlag, Berlin-Wien-Oxford, 1996, S. 145-87 Meisel H: Hepatitis-B-Virus. In: Diagnostische Bibliothek Band 1: Virusdiagnostik (Hrg: T. Porstmann). Blackwell-Verlag, Berlin-Wien-Oxford, 1996, S. 203-31 Meisel H: Hepatitis-A-Virus. In: Diagnostische Bibliothek Band 1: Virusdiagnostik (Hrg: T. Porstmann). Blackwell-Verlag, Berlin-Wien-Oxford, 1996, S. 425-37 Meisel H: Genus-Delta-Virus. In: Diagnostische Bibliothek Band 1: Virusdiagnostik (Hrg: T. Porstmann). Blackwell-Verlag, Berlin-Wien-Oxford, 1996, S. 519-32 Reimer K, Meisel H: Humanes Cytomegalievirus. In: Diagnostische Bibliothek Band 1: Virusdiagnostik (Hrg: T. Porstmann). Blackwell-Verlag, Berlin-Wien-Oxford, 1996, S. 258-72

1995 Sibold C, Meisel H, Krüger DH, Darai G: Detection of hantavirus infection by polymerase chain reaction. In: Frontiers of Virology. PCR: Protocols for Diagnosis of Human and Animal Virus Diseases (Becker Y, Darai G, eds). Springer Press, Berlin-Heidelberg-New York, 1995, pp 393-402


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1994 Berzins I, Ulrich R, Meisel H, Krüger DH, Borisova G, Pumpens P, Grens E, Gelderblom H, Ladhoff AM, Schnitzler P, Darai G, Bautz EKF: Sites in the core antigen of hepatitis B virus allowing insertion of foreign epitopes. In: Vaccines 94 (Norrby E et al, eds). Cold Spring Harbor Laboratory Press, New York 1994, pp 301-8 Krüger DH: Host-controlled modification and restriction. In: Encyclopedia of Virology (Webster RG, Granoff A, eds). Academic Press, London-New York 1994, pp 669-74 Porst, Meisel H, Schmidt D: Langzeitprognose und Therapie der Virushepatitis C. In: Virushepatitis A bis E. Diagnose, Therapie, Prophylaxe (Maass G, Stück B, Hrsg.), Kilian-Verlag Marburg, 1994. S. 138-40 Roggendorf M, Meisel H, Viazov S, Wiese M, Zibert A: Neue Entwicklungen in der Diagnostik der Hepatitis C. In: Virushepatitis A bis E. Diagnose, Therapie, Prophylaxe (Maass G, Stück B, Hrsg.), Kilian-Verlag Marburg, 1994. S. 101-11

1993 Ulrich R, Meisel H, Soza A, Krüger DH, Ladhoff A, Borisova G, Pumpen P: Characterization of chimeric core particles of hepatitis B virus containing foreign epitopes. In: Vaccines 93 (Ginsberg HS et al, eds), Cold Spring Harbor Laboratory Press, New York 1993, pp 323-328

1992 Klaus S, Krüger DH, Meyer J: Bakterienviren. 300 Seiten, 144 Abb., 29 Tab., mit einem Geleitwort von E. Kellenberger. Gustav Fischer Verlag, Jena-Stuttgart-New York, 1992, ISBN 3-334-60353-9 Klimov AI, Markushin SG, Prösch S, Sokolov NI, Heider H, Heider AM, Ginzburg VP, Gorodkova NV, Gambaryan AS, Matrosovich MN, Cox NJ, Webster RG: Some aspects of using antiviral compounds in the treatment and control of influenza virus infection. In: Avian Influenza – A Global Problem (Proceedings of the 3rd International Symposium on Avian Influenza), University of Wisconsin-Madison Publ. 1992, pp. 354-67

1990 Krüger DH, Bickle TA, Reuter M, Pein CD, Schroeder C: DNA methylation and restriction processes in Escherichia coli: Insights by use of bacterial viruses T3 and T7. In: Nucleic Acids Methylation (Clawson GA et al., eds). Alan R. Liss, Inc., New York, 1990, pp 113-24

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Die 10 am häufigsten zitierten Publikationen 1990-2015

70

Anlagen

71

Anlagen

Öffentliche Institutskolloquien/Gastvorlesungen 2015

Datum Referent Thema

16.04. Lüder Wiebusch

Charité Universitätsmedizin Berlin, Klinik für Pädiatrie m. S. Endokrino-logie, Gastroenterologie und Stoff-wechselmedizin

Synthetic lethal mutations in the cyclin A interface of human cytomegalovirus

30.04. Jan Felix Drexler

Institut für Virologie, Universität Bonn

Emerging viruses from animal reservoirs

07.05. Eike Steinmann

TWINCORE Center for Experimental and Clinical Infection Research GmbH, Hannover

Dissecting molecular and clinical pathways of hepatitis C virus trans-mission

28.05. Christine Rohde

Kuratorin der Spezialsammlungen Phagen, Plasmide und E. coli, Leibniz-Institut DSMZ, Braunschweig

Bacteriophages in research and appli-cation – status quo, perspectives, and limits 100 years after their discovery

04.06. Anna Papa

Medical School, Aristotle University of Thessaloniki, Greece

Emergence of arbo- and rodent-borne viruses in South-East Europe

18.06. Chiara Romagnani

Deutsches Rheumaforschungs-zentrum, Berlin

Epigenetic imprinting of the IFNG locus in natural killer cells

25.06. Antti Vaheri

University of Helsinki, Haartman Institute, Dept. of Virology

Vascular leakage and pathophysiology in infectious diseases – Emphasis on hantavirus disease and novel therapies

09.07. Christina Wege

Universität Stuttgart, Institut für Biomaterialien und Biomolekulare Systeme, Abt. Molekularbiologie und Virologie der Pflanzen

From crop threats to smart tools: the prospects of being plant virus

16.07. Kristina Allers

Charité Universitätsmedizin Berlin, Med. Klinik für Gastroenterologie, Infektiologie und Rheumatologie

Immunologische und morphologische Veränderungen im Gastrointestinaltrakt von Patienten mit HIV-Infektion

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„Seminarsprecher des Jahres“ des Instituts für Virologie

1990 W. H. Gerlich, Göttingen/Gießen

1991 H. Gelderblom, Berlin

1992 A. S. von Kekulé, Martinsried

1993 R. Kurth, Langen

1994 U. Heinemann, Berlin-Buch

1995 T. Mettenleiter, Insel Riems

1996 Å. Lundkvist, Stockholm

1997 L. Gürtler, München

1998 A. Kage, Berlin

1999 T. F. Meyer, Tübingen/Berlin

2000 K. Hamprecht, Tübingen

2001 L. Gürtler, Greifswald

2002 J. Sinclair, Cambridge

2003 S. Becker, Marburg

2004 A. Radbruch, Berlin

2005 B. Gärtner, Homburg

2006 M. van Ranst, Leuven

2007 P. Stäheli, Freiburg

2008 L. Gürtler, Frankfurt/Main

2009 T. Berg, Berlin

2010 F. Leendertz, Berlin

2011 E. Fichet-Calvet, Paris/Hamburg

2012 A. Greenwood, Berlin

2013 M. Lehmann, Berlin

2014 M. Beekes, Berlin

2015 C. Wege, Stuttgart

Seit 1990 wählen die akademischen Mitarbeiter des Institutes den Gastdozenten der öffentlichen Institutskolloquien/Gastvorlesungen, der als „Seminarsprecher des Jahres“ geehrt wird.

Documents

Publikationsverzeichnis 1990-2015 · 2016-02-24 · Virus Genes 48 (2014) 184-8 Full F, Jungnickl D, Reuter N, Bogner E, Brulois K, Scholz B, Stürzl M, Myoung J, Jung JU, Stamminger