Ratri Penyakit Kulit Karena Virus Kuliah

8/17/2019 Ratri Penyakit Kulit Karena Virus Kuliah

1/57


2/57

1. Varicella zoster virus (VZV)

2. Herpes simplex virus (HSV) type 1, 2

3. Cytomegalovirus (CMV)

. !pstei"#$arr virus (!$V)

%. Huma" &erpes virus #', #, a" #* (HHV#',

, *)

'.

Herpes virus simiae ($ virus), ll


3/57

+ate"t

"-esi seumur &iup

/umat#umata"


4/57

Herpes orola0ial HSV 1

Herpes ge"ital HSV 2

/+S4/S 54!/S S$$

1. 6rue primary i"-ectio" pertama alio"ta e"ga" virus

2. 5o"primary i"itial episoe partialcross immu"ity

3. 7ecurre"t


5/57

6za"c smear tia spesi-i

8irect -luoresce"t a"ti0oy test

Cultur virus

9C7 Si" 0iopsi

6es serologi


6/57


7/57

Me"ge"ai 0i0ir a" :a;a&

"itial i"-esi asimtomati

1< 0erupa &erpetic gi"givostomatitis

Ma"i-estasi li"is ter0a"ya 0erupa col sore atau-ever 0lister (=%


8/57

+esi 0erupa umpula" vesiel iatas uliteritema ter0a"ya paa 0i0ir eat vermillio"

Se0elum"ya aa rasa gatal atau pa"as paatempat lesi

4ator preisposisi # Si"ar mata&ari (>V$)

# /elela&a"

# Me"struasi# 8ll


9/57


10/57


11/57

Herpetic sycosis Herpes ?laiatorium Herpetic eratoco";u"ctivitis

Herpetic :&itlo: 7ecurre"t eryt&ema multi-orme mi"or# ise0a0a" recurre"t &erpes simplex(HSV 1 orola0ial)

# H!M (H!79!S SS@C6!8 !7A6H!M M>+64@7M!)# /li"is lesi target


12/57


13/57


14/57


15/57


16/57

HSV 2 9e"ulara" le:at o"ta la"gsu"g (ativitas

sesual) symtomatic s&ai"g 9e"ulara" terutama paa saat

# >"recog"ize out0reas# Su0cli"ical out0reas

/li"is 0erupa umpula" vesiel a" erosi, lu"a,sem0u& ta"pa 0eas

Seri"g am0u& # epresi 6rue primary i"-ectio" &erpetic vulvovagi"itis


17/57


18/57


19/57

Satu ari 3BBB persali"a" ta&u" i >S 6er;ai paa saat mela&ira" "-esi i"trauteri ge"ital &erpes primer saat

&amil elai"a" -etus lesi ulit a" sar,→mirose-ali ll, D atau elai"a" "eurologis→

HSV 2 (B


20/57


21/57

/aposiEs varicelli-orm eruptio"

Se0or&eic ermatitis, sca0ies, pemp&igus a" lai"#

lai"


22/57


23/57


24/57

silovir oral % x 2BB mg, -amciclovir 2 x 2%Bmg, valacyclovir 2 x %BB mg selama % &ari

!-e sampi"g ;ara"g 8ieluara" melalui gi";al /elai"a" -u"gsi gi";al osis iura"gi Valacyclovir a" -amciclovir a0sor0si le0i&

0ai -reue"si pem0eria" iura"gi Seri"g umat (' 12xt&" i0eria" osis

supresi) ag osis BB mg 2 x se&ari atau2BB mg 3 x se&ari

7esiste" t& asilovir i0eria" -oscar"eti"trave"us


25/57

"-esi primer varicella zoster virus (VZV) =B< ter;ai paa a"a#a"a F 1B 6H5 Masa i"u0asi 1B 21 &ari 9e"ulara"

# /o"ta la"gsu"g lesi# 7espirasi# 7epliasi i"isial paa "asop&ary"x a"co";u"ctiv

i"isial viremia, seei"g i liver, lu"gs,

splee" ll# Viremia seu"er (11 2B &ari) i"-esi iepiermis

varicella


26/57

Masa i"-esius &ari se0elum a" %&ari setela& tim0ul"ya lesi

/li"is vesiel i atas ulit eritema,pustule, rusta, erosi, e"ga" 0eas&ipopigme"tasi atau &iperpigme"tasi lesi polimor-. +esi mulai itu0u&me"ye0ar e estremitas


27/57

/@M9+/S

# "-esi seu"er# @steomyelitis

# 9"eumo"i

# Cere0ellar ataxia

# !"cep&alitis

# symptomatic myocaritis a" &epatitis

# 7eyeEs sy"rome &epatitis a" aut

e"cep&alopat&y are"a pem0eria" aspiri"

# Symptomatic t&rom0ocytope"ia

# 9urpura -ulmi"a"s


28/57

8?5@SS # /li"is

# +a0oratorium1. 6za"c smear multi"ucleate gia"t cells2. 8irect -luoresce"t a"ti0oy test

9!5?@$65 # 8imulai sei"i mu"gi"# cyclovir 2B mgg 00 (mas *BB mgose)% x se&ari selama % &ari


29/57


30/57


31/57


32/57

9aa e&amila" 2B mi"ggu me";ai co"ge"italvaricella sy"rome &ypoplastic lim0s,cuta"eous scars, ocular a" C5S isease

# Varicella p"eumo"i paa i0u

# 0ortus spo"ta"# 4etal eat&

Varicella "eo"atus

# % &ari se0elum a" 2 &ari setela& mela&ira"

# Varisela paa umur % 1B &ari#?e;ala 0erat

#9e"go0ata" asilovir iv


33/57

"sie" me"i"gat e"ga" 0ertam0a&"ya umur Zoster ↑

# /eaaa" imu"osupresi- # /ega"asa"# "-esi HV

/li"is # 8istri0usi u"ilateral sesuai ermatom ter0a"yame"ge"ai

torax %%


34/57

Zoster o-talmia

# $ila u;u"g &iu"g terapat lesi (ca0a"g ". "asociliary) me"u";ua" mata tere"a

(&utc&i"so"Es sig")# +esi 0erupa uveitis (=2


35/57

8iag"osis

# /li"is

# +a0

9e"go0ata"# cyclovir, valacyclovir, -amciclovir


36/57


37/57


38/57


39/57

• Rubeola.

• 9e"yait epiemi, 3B#B ;uta asus i u"ia,%3B.BBB me"i"ggal

•

Se0elum aa"ya vasi", epiemicampa ter;ai setiap 2#% ta&u" paa a"aumur %#= ta&u"

• /ema;ua" program imu"isasi i "egara

0erem0a"g me"cega& :a0a& a"me"uru"a" a"ga esaita" G ematia"


40/57


41/57

• ?e;ala proromal emam, malaise,o";u"gtivitis, coryza, a" 0atu

• 6a"a patog"omo"i Koplik Spot lesi puti&

ecil ielili"gi ole& &alo eritematosa “grainsof sand”, paa muosa 0ual eat molareua

• Mu"cul 1#2 &ari se0elum a" 0erta&a"

&i"gga 2 &ari setela& mu"cul"ya elai"a"ulit.


42/57

• /opli Spot


43/57

/eseluru&a" pe"yait 0erla"gsu"g selama 1B&ari

?e;ala lai" mu"ta&, iare, "yeri perut,pem0esara" lie", -ari"gitis, pem0esara"ele";ar lim-e ge"eralisata


44/57


45/57


46/57


47/57


48/57


49/57


50/57

sinonim: Common wart, dangkangan

tiologi: !uman "apilloma #irus$!"#% tipe&,',(,)',*),+


51/57

!piemiologi

9aa usia %# 2B t&, ;ara"g 3% t&

6er;ai p area yg seri"g o"ta e"ga" air

6ua"g agi"g, ia"DD verua paa ta"ga"


52/57

9reilesi ta"ga" (;ari a" telapata"ga",periu"gual (p org g e0iasaa"me"ggigit uu)

+esi 0eruura" pi"t poi"t % mm, 0erem0a"galam mi"ggu &i"gga 0ula"a"

+esi $erupa papul 0er0e"tu 0ulat e"ga"permuaa" asar(veruosa)0er:ar"a ea0ua"

Verua tia memilii ermatoglyp&ic(lipat sii;ari) yg mem0eaa""ya e"ga" alus

9e"ye0ara" e 0agia" tu0u& lai" melaluiautoi"oulasi

Veruavili-ormis atau igitate paa :a;a& a"salp, tampa seperti uri ya"g me"a"cap paaulit


53/57


54/57


55/57


56/57


57/57

Documents

Ratri Penyakit Kulit Karena Virus Kuliah