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RealTime Dynamix™: Rheumatoid Arthritis EU Q1 2017 With the recent approval of two new JAK inhibitors and the imminent introduction of additional IL-6 inhibitors, EU rheumatologists anticipate substantial practice shifts in RA management. Spherix Global Insights recently released data collected from 257 rheumatologists in France, Germany, Italy, Spain and the UK, revealing a high unmet need for small molecules and alternate mechanism biologics for the treatment of rheumatoid arthritis (RA). Check out some highlights from this report: RealTime Dynamix™: provides rapid response trending on the key issues affecting the Rheumatology market. Every other quarter ~250 qualified EU-based rheumatologists participate in an online survey. For more information contact: [email protected] Surveyed rheumatologists across all EU5 countries reported RA practice shifts, with the majority noting the introduction of biosimilars

RealTime Dynamix™: Rheumatoid Arthritis EU Q1 2017 · RealTime Dynamix™: Rheumatoid Arthritis EU Q1 2017 With the recent approval of two new JAK inhibitors and the imminent introduction

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RealTime Dynamix™: Rheumatoid Arthritis EU Q1 2017

With the recent approval of two new JAK inhibitors and the imminent introduction of additional

IL-6 inhibitors, EU rheumatologists anticipate substantial practice shifts in RA management.

Spherix Global Insights recently released data collected from 257 rheumatologists

in France, Germany, Italy, Spain and the UK, revealing a high unmet need for small molecules and

alternate mechanism biologics for the treatment of rheumatoid arthritis (RA). Check out some

highlights from this report:

RealTime Dynamix™: provides rapid response trending on the key issues affecting the Rheumatology market.

Every other quarter ~250 qualified EU-based rheumatologists participate in an online survey.

For more information contact: [email protected]

Surveyed rheumatologists across all EU5 countries reported RA practice shifts, with the majority

noting the introduction of biosimilars

Invest In Intelligence That Delivers

[email protected]

Similar to the US, the established SC TNF

inhibitors, etanercept and adalimumab, capture

the greatest biologic share across the EU5…

...However, unlike the US, RoActemra

accounts for the third greatest proportion of

share, capturing 12% of EU5 RA biologics use.

...When asked to choose

between a new JAK or new

IL-6 inhibitor for the treatment

of RA, nearly three-quarters of

respondents opted for a new

JAK

However, when pinned against the first approved JAK

on the EU market, Olumiant, rheumatologists would

prefer Olumiant over Xeljanz

2:1

With the recent approvals of Eli

Lilly/Incyte’s Olumiant and

Pfizer’s Xeljanz, they will be

getting what they want

With RoActemra’s deeper penetration in the EU5 market, the IL-6 inhibitors in development, Sanofi/

Regeneron’s Kevzara (sarilumab) and Janssen/GSK’s sirukumab, have a potential opportunity to

capitalize on converting RoActemra share. Indeed, over one-quarter of EU5 rheumatologists believe

the new IL-6 inhibitors will be completely interchangeable with RoActemra. However...