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Date 重複量數、線性混合模型 13516星期四

repeated-measure-ANOVA

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  • Date

    13516

  • t test for independent samples t

    Completely Randomized Design (CRD)

    Randomized Block Design (RBD)

    Latin Square Design (LSD)

    Completely Randomized Factorial Design (CRFD)

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  • DV

    1. IV

    2.

    3.

    4./

    5.

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  • (randomization)

    (treatments)(order)

    (blocking)

    (Blocks)

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  • dependent samples

    (threats of internal validity)

    (repeated measure)

    (blocking, subject matching)

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  • Completely Randomized Design (CRD, CR-p)

    Yij = + !j + "i(j) (i = 1,..., n; j = 1,...,p)

    "ij = Yij !j

    Randomized Block Design (RBD, RB-p)

    Yij = + !j + #i + "ij (i = 1,..., n; j = 1,...,p)

    "ij = Yij !j #i

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  • Repeated measure ANOVA

    subjectfactorlevel

    F

    practice effectcarryover effect

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  • within factor

    between factor

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  • Awithin factor2Bwithin factor3A1B1A1B2A1B3A2B1A2B2A2B3Y

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  • Abetween factor2Bwithin factor3A1A2B1B2B3Y

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  • Lee et al.(2004, 2005).

    CI Consistency Index

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  • Lee et al.(2004, 2005).

    CI=1 CI=0.5

    CI=0.33 CI=0.01CI Consistency Index

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  • Lee et al.(2005).

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  • statistical assumptionY

    assumption of sphericity

    MauchlyFFFepsilonGreenhouse-Geisser (G-G) Huynh-Feldt (H-F)

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  • Data from Vasey and Thayer (1987):

    (EMG)

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  • EMG

    0

    20

    40

    60

    80

    A_relax B_posi C_agita D_sad 16

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  • F (3, 63) = 11.51, p < .001, = 0.48

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  • t

    (normality test) Wilcoxon rank test

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  • 12...

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  • 12...

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  • (linear-mixed effect model)

    EMG

    0

    20

    40

    60

    80

    A_relax B_posi C_agita D_sad

    21

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  • EMG

    Q 1:

    Q 2: ()

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  • emotion

    EM

    G a

    mpl

    itude

    0

    20

    40

    60

    80

    A_relaxB_posiC_agitaD_sad

    s1 s10

    A_relaxB_posiC_agitaD_sad

    s11 s12

    A_relaxB_posiC_agitaD_sad

    s13 s14

    s15 s16 s17 s18 s19

    0

    20

    40

    60

    80s2

    0

    20

    40

    60

    80s20 s21 s22 s3 s4 s5

    s6

    A_relaxB_posiC_agitaD_sad

    s7 s8

    A_relaxB_posiC_agitaD_sad

    0

    20

    40

    60

    80s9

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  • s3s4s13s14s2s15s1s12s20s9s18s7s6s17s5s16s8s10s19s11s21s22

    -50 0 50

    (Intercept) emotionB_posis3s4s13s14s2s15s1s12s20s9s18s7s6s17s5s16s8s10s19s11s21s22

    emotionC_agita

    -50 0 50

    emotionD_sad

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  • (Intercept)

    -20 0 10 20 30 -40 -20 0 20 40

    -20

    010

    2030

    -20

    010

    30

    emotionB_posi

    emotionC_agita

    -20

    010

    30

    -20 -10 0 10 20 30

    -40

    020

    40

    -20 0 10 20 30

    emotionD_sad

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  • Tarkiainen et al. (1999) 1: (0 ~ 4)

    2: (0% ~ 24%)

    0% (symb)

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  • Tarkiainen et al. (1999)

    M100 response

    M170 response

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  • Tarkiainen et al. (1999)

    M100 response

    M170 response

    # M100 response varies in intensity with visual noise

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  • Tarkiainen et al. (1999)

    M100 response

    M170 response

    # M100 response varies in intensity with visual noise# M170 response varies in intensity with string length

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  • Tarkiainen et al. (1999)

    M100 response

    M170 response

    # M100 response varies in intensity with visual noise# M170 response varies in intensity with string length# M170 response shows the difference between symbols and letters

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  • Reading-Related N170 response

    150ms~200ms after onsets have been well defined in both ERP & MEG studies. generated from fusiform gyrus

    lateralized to the left hemisphere fusiform gyrus (the visual word form area; Cohen et al., 2000)

    orthographic word-form detection

    (Bentin et al., 1999)

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  • (adapted from Dehaene et al., 2005)

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  • In studies of alphabetic languages, there are different measurements for different aspect of orthographic properties.e.g., letter length and bigram frequency

    In Chinese orthography, number of strokes is highly correlated with many factorsstrokes and frequency: r = -.14***strokes and phonetic combinability: r = -.14***strokes and semantic combinability: r = -.19*** (3967 phonograms)

    N170/ M170 can reflect: Letter length (Tarkiainen et al., 2002) Bigram frequency (Hauk et al., 2006) transition probability (Solomyak and Marantz, 2010) Expertise of words (Bentin et al., 1999; Wong et al., 2005)

    limitations of factorial design

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  • In studies of alphabetic languages, there are different measurements for different aspect of orthographic properties.e.g., letter length and bigram frequency

    In Chinese orthography, number of strokes is highly correlated with many factorsstrokes and frequency: r = -.14***strokes and phonetic combinability: r = -.14***strokes and semantic combinability: r = -.19*** (3967 phonograms)

    limitations of factorial design

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  • Solutions:single-trial analyses

    Dambacher, Kliegl, Hofmann, & Jacobs, 2006; Hauk et al., 2006; Solomyak & Marantz, 2009, 2009

    linear mixed model (Baayen et al., 2008).

    Measurement of MEG source activation by minimum-norm estimations

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  • Experimental Design

    400 real characters

    400 pseudo-characters and non-characters

    Task: lexical decision

    Subjects:10 native Chinese speakers, error rate: 9% (S.D.: 3%)5 English speakers, error rate: 50% (45~54)

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  • (fixed effects)(random effects)

    (maximum likelihood)

    Baayen et al. (2008) (Markov chain Monte Carlo sampling) Type-1 error

    Type I error rates across different methods (64 observations)

    Type I error rates across different methods (800 observations)

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  • Approximately, 80% of characters are phonograms (Zhou, 1978).These are made up of a phonetic radical and a semantic radical.

    semantic radical phonetic radical

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  • Variables for LMM analysis Random Variable

    Subjects, Items

    Fixed Variablestrial numbers (the rank of trials in the list)number of strokesphonetic combinabilitysemantic combinabilityfrequencynoun-to-verb ratiosemantic ambiguity

    physical level

    lexical level

    orthographic level

    semantic level

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  • Results of M100 analysis

    * p < .05; ** p < .01; *** p < .001

    Variables Beta Std. Error tvalue pMCMC Beta Std. Error tvalue pMCMC

    Chinese Participants LH M100; R2 = .202 = .20

    (Intercept) .0709 .0548 1.29 .2trial number .0001 .000 3.29 .001**number of s trokes .0028 .0012 2.35 .018*f requency .0128 .0084 1.53 .126phonetic com binability .002 .0012 1.65 .101semantic com binability .0001 .0001 1.38 .169semantic ambiguity .001 .0131 .08 .958NVratio .0035 .0046 .76 .456

    .002 .0012 1.65 .101semantic com binability .0001 .0001 1.38 .169semantic ambiguity .001 .0131 .08 .958NVratio .0035 .0046 .76 .456

    English Participants LH M100 ; R = .48

    .1517 .1145 1.33 .118

    .000 .000 .85 .392

    .003 .0015 2.04 .037*.0039 .0077 .51 .607.0008 .0015 .56 .577.000 .0001 .37 .706.0125 .0139 .9 .367.0032 .0056 .57 .58

    .0008 .0015 .56 .577.000 .0001 .37 .706.0125 .0139 .9 .367.0032 .0056 .57 .58

    Chinese Participants RH M100; R2 = .14

    (Intercept) .003 .0445 .07 .965trial number .0001 .000 4.06 < .001***number of s trokes .0045 .0013 3.57 < .001***f requency .0121 .0089

    Chinese Participants RH M100; R2 = .14

    (Intercept) .003 .0445 .07 .965trial number .0001 .000 4.06 < .001***number of s trokes .0045 .0013 3.57 < .001***f requency .0121 .0089 1.36 .16phonetic com binability .0034 .0013 2.68 .004**semantic com binability .0001 .0001 .79 .411semantic ambiguity .0038 .014 .27 .773NVratio .0063 .0049 1.27 .174

    English Participants RH M100; R2 = .25

    .1197 .0817 1.47 .177.000 .000 .04 .916.0028 .0017 1.61 .091

    English Participants RH M100; R2 = .25

    .1197 .0817 1.47 .177.000 .000 .04 .916.0028 .0017 1.61 .091.0052 .009 .58 .542.0012 .0017 .71 .472.0001 .0001 .71 .45.0066 .0164 .4 .661.0057 .0066 .86 .386

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  • The$contribu-ons$of$bilateral$occipital3temporal$regions$in$the$reading$of$Chinese$words$

    The$seman-c$combinability$eects$in$RH$M170$reects$the$decomposi-on$of$characters.$

    Eect$of$visual$complexity$in$LH$M170$suggests$that$LH$fusuform$gyrus$is$a$general$mechanism$for$visual$word$recogni-on.$

    (Hsu, Lee and Marantz, 2011)

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