Space Life Sciences Exploring Space | Enhancing Life Dreams and Possibilities: Planning for the Achievable Human Exploration Strategy – Extend and Sustain

Space Life SciencesExploring Space | Enhancing Life

Dreams and Possibilities: Planning for the Achievable

Human Exploration Strategy – Extend and Sustain Human Activities Across the Solar SystemMarch 28, 2012

Jeffrey R. Davis, MDDirector, Space Life Sciences, NASA

50th Robert H. Goddard Memorial Symposium

Space Life SciencesExploring Space | Enhancing Life 2

Strategic Initiatives

• 2007 SLSD Strategic Plan

– Mission Statement“To optimize human health and productivity for space exploration“

– Vision Statement"To become the recognized world leader in human health, performance and productivity for space exploration”

– Strategic Goalso Manage balanced internal/external portfolioo Drive health innovationso Drive human system integration innovationso Educate and inspire

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Strategic Initiatives

• Summary• Visioning exercise and strategic plan• Alliances benchmark 2008-2010• HBS collaborative innovation models and

collaborative projects 2008-2010 • Open innovation pilot project 2008-2010• Virtual center for collaboration established 2010:

NASA Human Health and Performance center• Pursue collaborative research models 2011• Develop Strategic Framework for Innovation

2011


Portfolio Definition

• Human System risks for space flight (our portfolio of work)• Evidence based risk management system

• 65 human system risks• Human System Risk Board formed April 2008 –integrates

research and operations—decisions made by one entity

• Developed Risk Management Analysis Tool (RMAT)• Captures vertical “standards to deliverables” process• Links risks for common elements

• Subject matter experts (risk owners) identify gaps in their research and technology portfolio

• Gaps became opportunities for open collaborative solutions


Portfolio Analysis

• Portfolio mapping – Dr. Gary Pisano, Harvard Business School (HBS)

• “Which Kind of Collaboration is Right for You” – Harvard Business Review, December 2008

• Workshop conducted by Dr. Pisano with NASA – Wyle leadership team July 2009

• Analyzed 12 gaps for collaborative opportunity, those that mapped to open innovation quadrant selected for pilot projects


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Portfolio Analysis: Mapping - Models of Collaboration

From Gary Pisano, Harvard Business School


Internal innovation – “elite circle”

• Internal innovation projects

• Procure and adapt – retinal camera example

• New development – intravenous fluid from potable water

• Modified technology – colorimetric water analysis (formerly a device to evaluate paint color)

• Air quality – adapt a commercial device for another purpose


Remote Eye ImagingPreflight PostflightDiscovery of changes in eyes

prompted the need for remote eye imaging on ISS as soon as possible

Found solution from aWisconsin Optometrist who hadinvented a remote camera for an ophthalmoscope for use with hispatients on remote islands

New scope was flown withinweeks and successfully began monitoring changes in the eye.


Colorimetric Water Quality Monitoring Kit (CWQMK)

• Silver(I) and iodine are biocides in spacecraft drinking water storage and distribution systems

• U.S. Water Recovery System uses Iodineo Low iodine levels allow microbial growtho Long term consumption of high I2 levels can cause thyroid dysfunction

• ISS Russian segment uses Silver (Ag+)o Long-term consumption of high silver levels can cause Argyria (irreversible blue-

gray discoloration of the skin)

• Current biocide monitoring approach relies on archive samples which are collected in-flight, stored, then returned to ground and analyzed at JSC. Issues:o Techniques and/or hardware not in-flight deployableo Biocide levels subject to sample degradation during storage and transport

Hardware Description

• Solution is a simple, compact, hand-held device that reliably and rapidly measures key water quality indicators in-flight

• Water sample is passed through membrane cartridge resulting in color change on membrane surface in the presence of silver or iodine

• Commercially available Diffuse Reflectance Spectrophotometer (DRS) measures magnitude of color change, which is proportional to the amount of analyte present in sample volume

• CSPE water quality monitoring kit was delivered to ISS on STS 128/17A

CWQMK utilizes Colorimetric Solid Phase Extraction (CSPE) technology to protect crew health by providing the capability to perform in-flight measurements of iodine and silver levels in spacecraft potable water systems


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Exploration Medical Capability

IntraVenous fluid GENeration for exploration (IVGEN)

PRODUCE USP GRADE 0.9% NORMAL SALINE FROM IN SITU RESOURCES

• IV fluid required to respond to medical contingencies

• Filter to generate fluid incurs a smaller mass and volume cost than the actual fluid

• System based on deionization and sterilizing filters

FLIGHT TEST: MAY 4-7, 2010


Open Innovation

• Open innovation and collaboration– four pilot projects

• InnoCentive- posts individual challenges/gaps to their established network of solvers (~300,000)

• financial award if the solution is found viable by the posting entity

• Yet2.com- acts as an actual technology scout bringing together buyers and sellers of technologies

• Option to develop partnerships

• TopCoder - open innovation software company with a large network of solvers (~300,000)

• variety of skill-based software coding competitions

• NASA@work-internal collaboration platform leveraging expertise found across NASA’s 10 centers


INNOCENTIVE


NASA Pavilion on InnoCentive

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Global Appeal-

2900 solvers80 Countries


InnoCentive Pilot Results

Challenge Title Ctr Posted Deadline ProjRms Sub Award

DateAward

Amount

Improved Barrier Layers … Keeping Food Fresh in Space

JSC - SLSD 12/18/2009 2/28/2010 174 22 5/7/2010 $11,000

Mechanism for a Compact Aerobic Resistive Exercise Device

JSC - SLSD 12/18/2009 2/28/2010 564 95 5/14/2010 $20,000

Data-Driven Forecasting of Solar Events

JSC - SLSD 12/22/2009 3/22/2010 579 11 5/13/2010 $30,000

Coordination of Sensor Swarms for Extraterrestrial Research

LRC 2/27/2010 4/26/2010 423 37 6/4/2010 $18,000 (3)

Medical Consumables Tracking GRC 5/17/2010 7/27/2010 365 56 10/28/2010 $15,000 (3)

Augmenting the Exercise Experience

JSC - SLSD 5/27/2010 7/27/2010 229 18 9/20/2010 $10,000

Simple Microgravity Laundry System

JSC - EA 5/27/2010 7/27/2010 598 108 9/21/2010 $7,500


yet2.com


yet2.com Pilot ResultsTechnical Need No. of total

replies/leadsNo. of hits (initial interest)

Active leads

Bone Density Measurement 51 793 5

Monitoring of Water and Biocides

61 2003 8

Radioprotectants 28 475 6

Exoterrestrial Life Differentiation

31 1596 1

Food Packaging/Protection 29 173 5

Portable Imaging 34 581 5

Space Life SciencesExploring Space | Enhancing Life 17Page 17

Yet2.com example: Bone Imaging

Germany 6

Austria 1

Japan 7

Canada 1

France 6

Israel 1

Australia 3

Belgium 1

UK 5

Switzerland 4

Sweden 1

USA 15

Total 51


NASA@work


TopCoder Experience

• Opportunity presented to NASA by Harvard Business School

• Research project to compare outcomes of collaborative and competitive teams

• NASA provided the problem statement • Optimize algorithm that supports medical kit design

• Competition began on 11/04/2009 and lasted approximately 10 days

• 2800 solutions were submitted by 480 individuals

• Useful algorithm developed and incorporated into NASA model

• Team felt this process was more efficient than internal development

• Next steps – NASA Tournament Lab with HBS and TopCoder developed to seek many novel optimization algorithms for ISS


What is……..

What is……..

What is NASA Tournament Lab?

Create novel, high quality working software for algorithmic / computational Challenges

Contribute towards the development of empirically validated science

of innovation tournaments

Utilize the principles of distributed innovation to allow participants worldwide to contribute to solving mission challenges by developing innovative computational algorithms.

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Two Objectives –

Operational Virtual Facility developed between NASA, Harvard, and TopCoder

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NASA Human Health and Performance Center

• Membership– 110 members: http://nhhpc.nasa.gov– Seven NASA Centers– International Space Station partners: JAXA, DLR – Government orgs: FAA, GSA, USAF Research Labs, two NIH Centers, FDA,

USAID, ONR– Academia: FAA COE (Stanford), MIT, UTMB, Tufts, Clemson– Corporate: Philips, Johnson & Johnson, Procter & Gamble, General Mills,

Nike, GE, PepsiCo, InnoCentive, Yet2.com, Cazneau, Pitney Bowes, UnitedHealth Group, Kimberly-Clark

– Nonprofits: Mozilla, Southwest Research Institute, The National Center for Human Performance, San Diego Zoo, Draper Lab, Prize4Life

• Second Workshop: Connecting Through Collaboration – October 18, 2011

http://nhhpc.nasa.gov/


COECI

• Form Center of Excellence for Collaborative Innovation November 1, 2011– Organized to develop prizes for innovation and

other collaborative techniques– Located in the Human Exploration and Operations

Mission Directorate (HEOMD) – J Crusan, J Davis• Staffed by JSC Space Life Sciences personnel – NASA and

Wyle

– For all federal agencies; opportunity to expand into public-private partnerships

Documents

Space Life Sciences Exploring Space | Enhancing Life Dreams and Possibilities: Planning for the Achievable Human Exploration Strategy – Extend and Sustain