Springer€¦ · Soil Biology and Agriculture in the Tropics The relationships between soils, microbes and humans are of crucial relevance in the tropics, where plant stress and microbial

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springer.com Table of Contents 1

Life Sciences

Agriculture ................................................................................................................................................. 2

Animal Genetics and Genomics ................................................................................................................ 3

Animal Physiology ........................................................................................................................................ 3

Animal Systematics / Taxonomy / Biogeography .................................................................................. 4

Applied Ecology ........................................................................................................................................... 4

Bacteriology .................................................................................................................................................. 4

Behavioural Sciences ................................................................................................................................... 5

Biochemistry (general) ............................................................................................................................ 5

Biodiversity .................................................................................................................................................. 8

Bioinformatics (general) ............................................................................................................. 8

Biological Microscopy ................................................................................................................................ 9

Cell Biology ......................................................................................................................................... 10

Ecology (general) ............................................................................................................................ 13

Entomology ........................................................................................................................................... 14

Enzymology ............................................................................................................................................. 14

Evolutionary Biology ........................................................................................................................ 14

Fungus Genetics .................................................................................................................................... 15

Invertebrates ............................................................................................................................................... 15

Life Sciences (general) ............................................................................................................................... 15

Microbial Genetics and Genomics .......................................................................................................... 16

Microbiology (general) .............................................................................................................................. 16

Neurobiology .. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 17

Plant Anatomy / Development ................................................................................................................ 17

Plant Breeding / Biotechnology .............................................................................................................. 17

Plant Genetics and Genomics .................................................................................................................. 18

Plant Pathology ....................................................................................................................................... 19

Plant Physiology ........................................................................................................................................ 19

Plant Sciences (general) ............................................................................................................................ 20

Plant Systematics / Taxonomy / Biogeography .................................................................................... 21

Protein Science .......................................................................................................................................... 22

Proteomics .................................................................................................................... 22

Stem Cells ....................................................................................................................................... 22

Zoology (general) .................................................................................................................................. 23

springer.com Agriculture 2

Agriculture

F.M. Brouwer, M.K. Ittersum

Environmental and AgriculturalModeling:Integrated Approaches for Policy ImpactAssessment

Agriculture faces increasingly the challenge of balanc-ing its multiple functions in a sustainable way. Inte-grated assessment and modelling (IAM) can provideinsight into the potential impacts of policy changes.However, concepts to address the wide range of issuesand functions typical for agriculture are still scarce.The volume reviews and presents our current under-standing of integrated and working tools to assess andcompute, ex-ante, alternative agricultural and envi-ronmental policy options, allowing: 1. Analysis atthe full range of scales (farm to European Union andglobal), whilst focusing on the most important issuesemerging at each scale, 2. Analysis of the environmen-tal, economic and social contributions of agriculturalsystems towards sustainable rural development andrural viability, 3. Analysis of a broad range of issues,such as climate change, environmental policies, effectsof an enlarging EU, international competition andeffects on developing countries.

More on www.springer.com/978-90-481-3618-6Due January 2010

2010. XX, 325 p.978-90-481-3618-6 129,95 €

P. Dion

Soil Biology and Agriculture in theTropicsThe relationships between soils, microbes andhumans are of crucial relevance in the tropics, whereplant stress and microbial activity are exacerbated.

This volume of Soil Biology presents the living com-ponent of tropical soils, showing how it is shaped byenvironmental conditions and emphasizing its dra-matic impact on human survival and well-being. Fol-lowing an introduction to the specificities of tropicalsoils and of their microbial communities, the biolog-ical aspects of soil management are examined, deal-ing with land use change, conservation and slash-and-burn agriculture, the restoration of hot deserts, agro-forestry and paddy rice cultivation. As they are of par-ticular relevance for tropical agriculture, symbiosesof plants and microbes are thoroughly covered, as arethe biodegradation of pesticides and health risks asso-ciated with wastewater irrigation. Lastly, traditionalsoil knowledge is discussed as a key to our sustainablepresence in this world.

More on www.springer.com/978-3-642-05075-6Due January 2010

2010. XII, 350 p. (Soil Biology, 21)978-3-642-05075-6 approx. 149,95 €

Forthcoming

E. Lichtfouse

Genetic Engineering,Biofertilisation, Soil Quality andOrganic FarmingSustainable agriculture is a rapidly growing fieldaiming at producing food and energy in a sustain-able way for humans and their children. Sustain-able agriculture is a discipline that addresses currentissues such as climate change, increasing food andfuel prices, poor-nation starvation, rich-nation obe-sity, water pollution, soil erosion, fertility loss, pestcontrol, and biodiversity depletion. Novel, environ-mentally-friendly solutions are proposed based onintegrated knowledge from sciences as diverse asagronomy, soil science, molecular biology, chemistry,toxicology, ecology, economy, and social sciences.Indeed, sustainable agriculture decipher mechanismsof processes that occur from the molecular level tothe farming system to the global level at time scalesranging from seconds to centuries. For that, scien-tists use the system approach that involves studyingcomponents and interactions of a whole system toaddress scientific, economic and social issues. In thatrespect, sustainable agriculture is not a classical, nar-row science. Instead of solving problems using theclassical painkiller approach that treats only nega-tive impacts, sustainable agriculture treats problemsources. Because most actual society issues are nowintertwined, global, and fast-developing, sustainableagriculture will bring solutions to build a safer world.This book series gathers review articles that analyzecurrent agricultural issues and knowledge, then pro-pose alternative solutions. It will therefore help allscientists, decision-makers, professors, farmers andpoliticians who wish to build a safe agriculture, energyand food system for future generations.

More on www.springer.com/978-90-481-8740-9Due April 2010

2010. Approx. 400 p. (Sustainable Agriculture Reviews, 4)978-90-481-8740-9 approx. 149,95 €

Forthcoming

T. Lim

Medicinal and Non-medicinalEdible Plants, Vol. 1This work aims to create awareness and interest inthe rich and diverse array of edible medicinal andnon-medicinal plants in a multi-compendium for-mat. The edible species dealt with in the book includeto a larger extent lesser-known, wild and underuti-lized crops and some common and widely growncrops that are consumed as fruits, vegetables, culi-nary herbs, pulses, cereals, spices and condiments,root crops, beverages, mushrooms, edible oils andstimulants. Vegetables covered include species culti-vated for their fruits, seeds, flowers, leaves, petioles,shoots and roots or tubers. All relevant available andup-to-date information collated on more than a thou-sand species of edible, medicinal and non-medicinalplants will be provided in a comprehensive referenceseries fully illustrated with copious coloured images tohelp in edible plant and plant part identification. Eachvolume will cover about a hundred edible species inalphabetical order. Unlike other books on similar sub-jects under each species, there will be coloured plateson edible plant and plant parts followed by detailedinformation arranged in a logical and easy-to-followformat that covers the taxonomy (botanical name andsynonyms), common English and vernacular names;origin and distribution; agroecological requirements;edible plant part and uses; plant habit and descrip-tion; nutritive and medicinal/pharmacological val-ues, uses and relevant research; other non-edible uses;and selected/cited references for further reading. Thiswork will not cover cultivation aspects as the agron-omy of many of the traditional and wild, indigenousspecies has been little studied or published and forthose that are commonly or extensively cultivatedthere is a plethora of information that have been pub-lished in many text and reference books. The first fewvolumes will focus on edible fruit crops used as foodfollowed by those used as vegetables. Besides indicesfor scientific and common names, two glossaries areprovided, one for medical terms and another for otherscientific terms. This work will be of significant inter-est to scientists, researchers, practitioners (medicalpractitioners, pharmacologists, ethnobotanists, horti-culturists, food nutritionists, agriculturists, botanists,herbalogists, herbologists, naturalists, conservation-ists, extension scientists, teachers, lecturers), studentsand the general public.

More on www.springer.com/978-90-481-8660-0Due March 2010

2010. Approx. 500 p.978-90-481-8660-0 approx. 149,95 €

2 Agriculture springer.com

springer.com Animal Genetics and Genomics 3

I.H. Williams

Biocontrol-Based Integrated

Management of Oilseed Rape

Pests

Oilseed rape is a major arable crop in both Europe

and North America. It is attacked by unique com-

plexes of insect pests still largely controlled through

the application of chemical insecticides. Crop man-

agement systems for the future must combine sustain-

ability with environmental acceptability to satisfy both

social and economic demands. This book, in its 17

chapters each led by a world expert, reviews research

progress towards developing integrated pest man-

agement systems for the crop that enhance conserva-

tion biocontrol. This approach is particularly timely

because of the development in Europe of insecticide

resistance in the pollen beetle, a major pest of the

crop. The past decade has seen considerable progress

in our knowledge of the parasitoids and predators

that contribute to biocontrol, of their distribution pat-

terns, and their behavioural ecology, both within and

without the crop. There is potential for natural enemy

conservation through modification of within-field

crop husbandry practices, as well as, on the landscape

scale, through habitat manipulation to encourage veg-

etational diversity. This book will prove invaluable as

a text for researchers, university teachers, graduate

scientists, extension workers and growers involved in

integrated pest management.

More on www.springer.com/978-90-481-3982-8

Due April 2010

2010. Approx. 500 p. 30 illus. in color.

978-90-481-3982-8 ▶ approx. 169,95 €

Animal Genetics and Genomics

M. Sioud

RNA Therapeutics

Function, Design, and Delivery

Central to the synthesis of proteins, the performance

of catalysis, and many other physiological processes,

the aberrant expression of which can be linked to

human diseases including cancers, RNA has proven

to be key target for therapeutics as well as a tool for

therapy. In RNA Therapeutics: Function, Design,

and Delivery, expert contributors from a broad spec-

trum of scientific backgrounds highlight the roles

that messenger RNAs and small RNAs can play in

biology and medicine. While covering the five major

RNA-based drugs, namely the use of ribozymes to

cleave and/or correct mRNA transcript, the use of

siRNA for targeted silencing of gene transcripts, the

use of aptamers, like short RNA molecules, for neu-

tralizing the protein functions, the use mRNA-trans-

fected DCs to activate immune system against tumor

cells, as well as the use of RNA to reprogram T and/

or DC cell function, this extensive volume brings

together the fields of coding (mRNA) and non-cod-

ing RNA such as ribozymes, RNAse P, siRNAs, and

miRNAs into one convenient source. Written in the

highly successful Methods in Molecular Biology™

series format, the cutting-edge protocol chapters con-

tain introductions to their respective topics, lists of

the necessary materials and reagents, step-by-step,

readily reproducible laboratory protocols, and practi-

cal tips on troubleshooting and avoiding known pit-

falls. Also, the book contains several excellent reviews

for teaching purposes. Authoritative and comprehen-

sive, RNA Therapeutics: Function, Design, and Deliv-

ery provides key models and tools which will assist

researchers in increasing our understanding of RNA

functions, modifications, and their involvement in

diseases in order to lead to the design of vital new

RNA-based therapeutics.


Due March 2010

2010. Approx. 485 p. 100 illus. (Methods in Molecular

Biology, 629)

978-1-60761-656-6 ▶ 109,95 €

Animal Physiology

G.A. Gerencser

Epithelial Transport Physiology

The general theme of Epithelial Transport Physi-

ology is epithelial transport of molecules and ions,

which includes the regulation of these mechanisms

either directly, through secondary messengers, or via

nuclear commands. Biologic transport of ions and,

or, molecules across epithelial bio-membranes are

mediated by proteins or protein-based molecules.

Over the past forty to forty-five years, the primary

structures of many of these proteins have been elu-

cidated. One of the universalities that has emerged

during this investigative process is the commonal-

ity of function amongst epithelial transporters up

and down the phylogenetic tree of animals. The cen-

tral subject of Epithelial Transport Physiology is to

provide a comprehensive, contemporary review of

epithelial transport and the responsible transporter

proteins, while elucidating the wide spectrum of new

methods examining epithelial transporters such as

patch clamping, reconstitution, molecular biology

and molecular physiology that are now available for

the application to epithelial plasma membrane sys-

tems. Contributors to this volume were chosen by

the editor, George A. Gerencser, and were selected

for their outstanding accomplishments in the field,

and for their clarity and breadth of presentation.

Epithelial Transport Physiology is directed to both

basic and clinical scientists working in membrane

transport and related areas, to graduate students and

advanced undergraduates seeking a broad purview

of the subject, and to other investigators and poten-

tial investigators seeking a vista of the new frontiers of

molecular epithelial transporters.


Due January 2010

2010. XII, 488 p. 108 illus., 31 in color.

978-1-60327-228-5 ▶ 199,95 €

http://www.springer.com/978-90-481-3982-8



4 Animal Systematics / Taxonomy / Biogeography springer.com

Animal Systematics /

Taxonomy / Biogeography

N. Becker, D. Petric, M. Zgomba, C. Boase, M. Madon, C. Dahl,

A. Kaiser

Mosquitoes and Their Control

Mosquitoes and Their Control presents a wealth of

information on the bionomics, systematics, ecology,

research techniques and control of both nuisance and

disease vector mosquitoes in an easily readable style,

providing practical guidelines and important infor-

mation for professionals and laymen alike. Ninety-

two European species and more than 100 globally

important vector and nuisance species are included

in the book. Most of them, including all European

species, are described in the fully illustrated iden-

tification keys, followed by a detailed description

of the morphology, biology, distribution and med-

ical importance of each species, including over 700

detailed drawings. Mosquitoes and Their Control

includes: systematics and biology medical significance

research techniques illustrated identification keys for

larval and adult mosquito genera morphology, ecol-

ogy, and distribution of the species identified in the

keys biological, chemical, physical and genetic con-

trol of mosquitoes Mosquitoes and Their Control is

a valuable tool for vector ecologists, entomologists,

and all those involved with mosquito control, biology,

ecology, and systematics world-wide. It will especially

benefit those professionals, scientists and students

dealing with mosquitoes and their control on a day-

to-day basis. Society as a whole stands to gain from

improved, environmentally responsible mosquito

management programs designed on the basis of a

broader understanding of mosquitoes and their con-

trol, as provided in this enlightening book.


Due January 2010

2010. XX, 639 p. 554 illus., 2 in color.

978-3-540-92873-7 ▶ 169,95 €

Applied Ecology

P.W. Atkinson

Vector Biology, Ecology and

Control

The control of mosquitoes and other insect vectors

of human pathogens in an area-wide, environmen-

tally and sustainable way is critical to solving global

health problems in the developing world but also to

industrialized countries that already have in place effi-

cient vector control programs. The rapid spread of

West Nile virus through the United States provides

one example of how even a highly developed coun-

try can be relatively powerless against the spread of

mosquito-borne disease. This volume illustrates how

the efforts over half a century of a single investiga-

tor, Mir S. Mulla, and his students and collabora-

tors have achieved sustainable vector insect control

in regions of the world extending from the south-

western United States to south-east Asia. These con-

trol strategies have been refined over these decades

and now are employed in a diversity of ecosystems.

Increased public awareness of global health and the

importance placed on this for the future well-being of

the entire human population makes the deployment

and refinement of these strategies even more timely.


Due January 2010

2010. XII, 260 p.

978-90-481-2457-2 ▶ 129,95 €

Forthcoming

W.J. Junk, M.T. Piedade, F. Wittmann, J. Schöngart, P. Parolin

Amazonian Floodplain Forests

Ecophysiology, Biodiversity and Sustainable

Management

Central Amazonian floodplain forests grow in areas

that are annually flooded by large rivers during mean

periods of up to 8 months and at depths of up to 10

m. Despite this severe stress, these forests consist of

over 1,000 species and are by far the most species-

rich floodplain forests worldwide. The trees show a

broad range of morphological, anatomical, physiolog-

ical, and phenological adaptations that enable them

not only to survive the adverse environmental condi-

tions, but also to produce large amounts of biomass

when the nutrient levels in water and soils are suf-

ficiently high. This is the case in the floodplains of

white-water rivers, which are used for fisheries, agri-

culture, and cattle-ranching but which also have a

high potential for the production of timber and non-

timber products, when adequately managed. This is

the first integrative book on the functioning and eco-

logically oriented use of floodplain forests in the trop-

ics and sub-tropics. It provides a solid scientific basis

for wetland ecologists, foresters, environmentalists,

and wetland managers. It is also an excellent textbook

for students working in Amazonian floodplain forests

and similar forest types in other regions.


Due May 2010

2010. Approx. 500 p. (Ecological Studies, 211)

978-90-481-8724-9 ▶ approx. 129,95 €

Bacteriology

J. Ramos, A. Filloux

Pseudomonas

Volume 6: Molecular Microbiology, Infection and

Biodiversity

The five previous volumes of Pseudomonas series

covered the biology of pseudomonads in a wide con-

text, including the niches they inhabit, the taxonomic

relations among members of this group, the molecu-

lar biology of gene expression in different niches and

under different environmental conditions, the anal-

ysis of virulence traits in plants, animals and human

pathogens as well as the determinants that make some

strains useful for biotechnological applications and

promotion of plant growth. Pseudomonas volume

6 is intended to collect new information on molec-

ular microbiology, infection and biodiversity. This

sixth volume covers the following topics: transcrip-

tion regulation, virulence control, physiology and

metabolism, bacteriology, microbial genetics and

genomics. Pseudomonas volume 6 will be of use to

researchers working on these bacteria, particularly

those studying genomics, physiology, quorum sens-

ing, life styles, metabolism etc. Advanced students in

biology, medicine and agronomy will also find this

volume a valuable reference during their studies.


Due February 2010

2010. Approx. 300 p.

978-90-481-3908-8 ▶ approx. 139,95 €





springer.com Behavioural Sciences 5

Behavioural Sciences

N. Anthes, R. Bergmüller, W. Blanckenhorn, H.J. Brockmann,

C. Fichtel, L. Fromhage, J. Frommen, W. Goymann, J. Heinze,

K. Hirschenhauser, H. Hofer, S. Kaiser, P. Kappeler, B. Kempe-

naers, G. Kerth, J.I. Korb, K. Kotrschal, C. Kraus, M. Manser, N.

Michiels, R. Moritz, M. Pahl, D. Penn, N. Sachser, M. Schaefer,

C.P. Schaik, J.M. Schneider, I. Schreiber, M. Taborsky, J. Tautz,

F. Trillmich, S. Zhang, P. Kappeler

Animal Behaviour: Evolution and

Mechanisms

The study of animal behaviour is one of the fastest

growing sub-disciplines in biology. The resulting

diversity of conceptual approaches and methodolog-

ical innovations makes it increasingly difficult for

professionals and students to keep abreast of impor-

tant new developments. This edited volume provides

up-to-date reviews that facilitate orientation in key

areas of animal behaviour, including communication,

cognition, conflict, cooperation, sexual selection and

behavioural variation. The contributions address evo-

lutionary and proximate aspects of behaviour and also

cover both invertebrates and vertebrates. Important

concepts are dealt with in separate glossaries and key

examples highlighted in separate text boxes. Richly

illustrated with colour figures, this volume offers a

well structured overview of all the main developments

in current animal behaviour research. It is ideal for

teaching upper-level courses, where it will be essential

reading for advanced students familiar with basic con-

cepts and ideas.


Due March 2010

2010. Approx. 620 p. 110 illus. in color.

978-3-642-02623-2 ▶ approx. 42,01 €

S. Gursky-Doyen, J. Supriatna

Indonesian Primates

Edited by two internationally renowned primatolo-

gists, this new text synthesizes current research on

the primates of Indonesia, which include apes, mon-

keys, and prosimians. It is published at a crucial time

as anxiety over the fate of the Indonesian primate

population is rising. One study concluded that more

than 70% of Asian primate species are threatened

with extinction, while 84% of the dozens of Indone-

sian primate species are threatened. In this volume,

the common thread of diversity is inextricably linked

to the theme of conservation. Contributed by key

researchers from around the world, the volume’s

chapters demonstrate the sheer variety in Indonesian

primates, ranging from Nekaris and Munds’ study of

using slow loris facial variation to distinguish species

to Delgado’s discussion of communication patterns

among orangutans. The book’s first section contains

chapters on the endangered orangutans and gibbons.

The orangutan, in its Sumatran and Bornean forms,

is the only Asian great ape; yet in Borneo, Sugardito

and Adhikerana nest densities are severely threat-

ened by logging activity, especially at national park

boundaries. The authors highlight the effectiveness

of community-based patrolling as a protective mea-

sure is becoming an increasingly effective means of

protecting orangutans. The second section of the

text examines the diversity of monkeys in Indone-

sia, with each author in turn stressing the importance

of conservation. Yorzinski uses the critically endan-

gered pig-tailed langur of the Indonesian Mentawai

Islands to demonstrate how isolated island primates

react to predation pressure, while further chapters

explore the relationship between vegetation and pri-

mate densities, habitat quality and its degradation,

and human--simian interaction. A further section

looks at the region’s prosimians and notes that the

taxonomic diversity is only recently being explored.

The cryptic/nocturnal nature of these primates makes

their conservation status even more uncertain. Sharon

Gursky-Doyen is an associate professor of anthropol-

ogy at Texas A&M University. She received her BA

from Hartwick College, her MS from the University

of New Mexico, and her Ph.D. from the State Univer-

sity of New York at Stony Brook. She has been study-

ing Sulawesi tarsiers since 1994. Her present research

is centered on understanding the effects of altitude on

the recently re-discovered pygmy tarsiers. She is the

author of numerous scientific publications including

The Spectral Tarsier, (Prentice Hall 2007); Primate

Anti-Predator Strategies (coedited with Anna Nekaris,

Springer 2007) as well as Tarsiers: Past, Present and

Future (co-edited with Patricia Wright and Elwyn

Simons, Rutgers University Press, 2003). Jatna Supri-

atna received his B.S. in Biology from Universitas

Nasional, Jakarta, and his M.S. and Ph.D. from the

University of New Mexico. He has worked for Con-

servation International since 1994 and has served as

the Vice President for Conservation International

Indonesia Program since 2005. In 1999, he received

the Golden Ark Award for his conservation work

from Prince Bernhard of the Netherlands. In 2009, he

received a Science Award also known as the Habibie

Award from former Indonesian President B.J. Habi-

bie. He has published 8 books on Indonesian Bio-

diversity and more than 90 articles in international

journals. His books include: Panduan Lapangan Pri-

mata Indonesia (Field Guide of Indonesia Primates),

Conservation Biology and Saving Indonesia's Nature.

The latter two books are among the best-selling envi-

ronment books in Indonesia.


Due February 2010

2010. Approx. 320 p. 74 illus., 14 in color. (Developments in

Primatology: Progress and Prospects, )

978-1-4419-1559-7 ▶ approx. 129,95 €

Biochemistry (general)

U. Albrecht

The Circadian Clock

This comprehensive book, written by experts in the

field, provides historical and current information

about the circadian clock, molecular properties of

clock components and their roles in health and dis-

ease. The Circadian Clock includes advances in sev-

eral aspects of clock research with chapters ranging

from gene expression, mathematical modeling, physi-

ology, neuroscience and comparitive biology. It aims

to give an integrated view how the biochemistry and

physiology of an organism is organized over the 24

hours of a day and how disturbance of clock function

can lead to disease. The Circadian Clock is an ideal

book for researchers, clinicians and graduate students

in the fields of biochemistry, cell biology, physiology,

neuroscience and bioinformatics.


Due January 2010

2010. XI, 300 p. 39 illus., 15 in color. (Protein Reviews,

12)

978-1-4419-1261-9 ▶ 119,95 €




6 Biochemistry (general) springer.com

D. Armstrong

Advanced Protocols in Oxidative

Stress II

Expanding upon the research elucidated by the first

volume of this collection, Advanced Protocols in

Oxidative Stress II presents thirty additional cut-

ting-edge chapters focusing on novel techniques for

detecting ROS/RNS, unique AOX technology and

applications, gene expression and biostatistics for

evaluating OS-derived experimental data. The inter-

national panel of authors also provide animal models

and numerous studies concentrating on mitochon-

dria during hypoxic conditions using advanced meth-

ods for pO2, peroxynitrate, reactive S-nitrosothiols,

lipid peroxides, COX, and the mitochondrial mem-

brane potential. Due to the dynamic nature of this

topic, this book is the second of several volumes of

Advanced Protocols in Oxidative Stress, all included

in the highly successful Methods in Molecular Biol-

ogy™ series. As part of the series, the chapters of this

volume present brief introductions to the respective

subjects, lists of the necessary materials and reagents,

step-by-step, readily reproducible laboratory proto-

cols, and tips on troubleshooting to ensure easy repli-

cation of the technology involved. Authoritative and

convenient, Advanced Protocols in Oxidative Stress

II is an ideal desk reference for scientists wishing to

further the research in this exciting, unique, and vital

field of study.


Due January 2010

2010. XII, 423 p. 139 illus., 1 in color. (Methods in Molecular

Biology, 594)

978-1-60761-410-4 ▶ 89,95 €

K. Balasubramanian, M. Burghard

Carbon Nanotubes

Methods and Protocols

Due to their rare combination of high chemical stabil-

ity, exceptional optical and electrical properties, high

surface-to-volume ratio, and high aspect ratio, carbon

nanotubes (CNTs) have made an enormous impact

on materials science, molecular biology, biomedicine,

and bioanalytical chemistry. Carbon Nanotubes:

Methods and Protocols provides reliable, consistent

protocols on the application of CNTs in molecular

biology-related fields. These are of vital importance,

as the commercially available CNTs differ in purity,

agglomeration state, as well as length and diame-

ter distribution, all of which have a profound influ-

ence on the dispersability and surface properties of

the tubes. The volume contains detailed sections on

functionalization, toxicity, trafficking, scaffolds, and

biosensors, provided by expert researchers from var-

ious fields. Written in the highly successful Methods

in Molecular Biology™ series format, chapters include

introductions to their respective topics, lists of the

necessary materials and reagents, step-by-step, readily

reproducible laboratory protocols, and notes on trou-

bleshooting and avoiding known pitfalls. Authorita-

tive and cutting-edge, Carbon Nanotubes: Methods

and Protocols serves to contribute to the achievement

of common standards and helps researchers to avoid

discrepancies in future biology-related CNT studies.


Due March 2010

2010. Approx. 250 p. 119 illus., 6 in color. (Methods in

Molecular Biology, 625)

978-1-60761-577-4 ▶ 94,95 €

R.W. Burry

Immunocytochemistry

A Practical Guide for Biomedical Research

Immunocytochemistry is a microscopic method that

uses antibodies to localize proteins in tissue sections

and cell cultures. Dr. Burry’s book is the first prac-

tical guide to planning, performing, and evaluat-

ing immunocytochemical experiments designed for

novice immunocytochemists. This book’s predom-

inant orientation is academic, focusing only on the

most productive methods, with a primary emphasis

on animal-based research tissues. The clear descrip-

tions of the methods are easily followed and the spe-

cific design charts show how to plan an experiment.

Included are a series of experimental cases exploring

actual mistakes that demonstrate the approaches pre-

sented. Immunocytochemistry is no longer consid-

ered a specialized technique - Immunocytochemistry:

A Practical Guide for Biomedical Research showcases

this mainstream morphological approach in an acces-

sible and exciting manner.


Due January 2010

2010. XV, 223 p. 82 illus., 8 in color.

978-1-4419-1303-6 ▶ 69,95 €

I.M. Clark

Matrix Metalloproteinase

Protocols

Since the discovery of a collagen-degrading pro-

tease in the tadpole tail in 1962, matrix metallopro-

teinase research has led to the discovery of more than

twenty distinct vertebrate MMPs, along with a vari-

ety of homologues from diverse organisms such as

the sea urchin, plants, insects, and nematode worms.

Fully updating and adding to the popular first edi-

tion, Matrix Metalloproteinase Protocols, Second Edi-

tion includes a series of state-of-the-art techniques

provided by eminent experts in the field. Beginning

with a brief overview of the MMP arena, from how

these enzymes fit into the larger degradome to what

occurs when their expression and function in the

mouse is modulated, the volume continues with sec-

tions on the expression and purification of MMPs and

TIMPs, the detection of MMPs and TIMPs at both

the protein and mRNA level, and our ability to assay

MMP and TIMP activities in a wide variety of circum-

stances. Written in the highly successful Methods in

Molecular Biology™ series format, chapters contain


necessary materials and reagents, step-by-step, readily


bleshooting and avoiding known pitfalls. Compre-

hensive and cutting-edge, Matrix Metalloproteinase

Protocols, Second Edition is an ideal source for many

of the essential laboratory techniques for both novice

and seasoned researchers alike collected in one conve-

nient volume.


Due March 2010



978-1-60327-298-8 ▶ 109,95 €





springer.com Biochemistry (general) 7

A. Economou

Protein Secretion


Over the past thirty years, many elegant genetic and

biochemical approaches have been combined in order

to advance the study of protein secretion and the

necessary navigation through cell membranes, yet,

despite this progress, less than two hundred mem-

brane protein structures are known, nowhere near

the complete inventory that the discovered protein

export systems suggest. In Protein Secretion: Meth-

ods and Protocols, leading experts in the field pro-

vide robust, well-established protocols to elucidate

the multiplicity of tools that have been developed to

study protein sorting, membrane targeting, trans-

membrane crossing, and secretion across multiple

membranes. With examples involving both prokary-

otic and eukaryotic organisms, the volume covers

subjects ranging from bioinformatics and proteomics

to fundamental enzymology and genetics to cell biol-

ogy, structural analyses, and biophysics. Written in

the highly successful Methods in Molecular Biol-

ogy™ series format, chapters contain introductions to

their respective topics, lists of the key materials and

reagents, step-by-step, readily reproducible proto-

cols, and detailed notes on troubleshooting and avoid-

ing known pitfalls. Comprehensive and dependable,

Protein Secretion: Methods and Protocols focuses on

well-characterized paradigms so that scientists study-

ing a vast array of subjects from biochemistry and

genetics to biotechnology and biopharmaceuticals can

benefit and expand upon their vital research.


Due February 2010



978-1-60327-167-7 ▶ 109,95 €

Forthcoming

J.R. Harris

Cholesterol Binding and

Cholesterol Transport Proteins:

Structure and Function in Health and Disease

Knowledge of cholesterol and its interaction with

protein molecules is of fundamental importance in

both animal and human biology. This book con-

tains 22 chapters, dealing in depth with structural

and functional aspects of the currently known and

extremely diverse unrelated families of choles-

terol-binding and cholesterol transport proteins. By

drawing together this range of topics the Editor has

attempted to correlate this broad field of study for the

first time. Technical aspects are given considerable

emphasis, particularly in relation cholesterol reporter

molecules and to the isolation and study of membrane

cholesterol- and sphingomyelin-rich "raft" domains.

Cell biological, biochemical and clinical topics are

included in this book, which serve to emphasize the

acknowledged and important benefits to be gained

from the study of cholesterol and cholesterol-bind-

ing proteins within the biomedical sciences and the

involvement of cholesterol in several clinical disor-

ders. It is hoped that by presenting this topic in this

integrated manner that an appreciation of the fact

that there is much more that needs to be taken into

account, studied and understood than the widely dis-

cussed "bad and good cholesterol" associated, respec-

tively, with the low- and high-density lipoproteins,

LDL and HDL.


Due March 2010

2010. Approx. 400 p. (Subcellular Biochemistry, 51)

978-90-481-8621-1 ▶ approx. 149,95 €

Forthcoming

D.V. Nicolau

Nanodevices Based on Protein

Molecular Motors

An Engineering Approach

This book reviews the state of the art in the design,

fabrication and operation of bio-nano-devices based

on protein molecular motors, as well as the chal-

lenges and the opportunities offered by alternative

architectures and possible applications. The focus of

the review will be on self-propelled machines, which

have the highest chances to develop in autonomous

dynamic nanodevices and systems of devices based on

protein molecular motors.


Due May 2010

2010. (Fundamental Biomedical Technologies, 105)

978-0-387-30755-8 ▶ approx. 104,95 €

Forthcoming

P.V. Vignais, P. Vignais

Discovering Life, Manufacturing

Life

How the experimental method shaped life

sciences

This book tells the story of how thinkers, over time,

have dared to explore using experimental devices and

how the experimental method established itself and

took a predominant role in the life sciences. While life

sciences continue to advance and knowledge becomes

more widespread and accessible, philosophers now

focus on problems of ethics particularly with respect

to the reproductive functions that contemporary biol-

ogy is able to manipulate and modify. Looking at the

stunning progress made by scientific thought over

the last five centuries we might ask ourselves what

were the triggering factors that lead to the experi-

mental method. How did this logical and objective

approach to the exploration of various enigmas in

nature arise and spread at a particular moment in

time in the western world? Was there an influence

from the social, religious or political context? Was

the energy of a few individuals sufficient to initiate

such a revolution? The authors of this book take us on

journey of the mind, from the ancient roots of scien-

tific rationality to today’s irresistible trend in genetic

manipulation, particularly focused on human beings.

Inevitably this will lead the reader to view the way

in which science is done today under a new light. A

fascinating discussion, based on concrete examples

and experiments, provides food for thought, not only

with respect to the experimental method itself, but

also regarding the organization of science as it exists

today and how it is perceived. About the authors:

Pierre V. Vignais, a science doctor and a doctor of

medicine, was awarded a scholarship of the Fonda-

tion Roux at the Pasteur Institute of Paris. Profes-

sor emeritus of Biochemistry of the medical college

of the University Joseph Fourier and director of a

URA-CNRS at the CEA (French Atomic Energy Com-

mission), he received the CNRS Silver Medal and

the Grand Prix de l'Académie des Sciences. He died,

aged 80, in September 2006. Paulette M. Vignais, his

wife, received her diploma in chemical engineering

from the Ecole Nationale Supérieure de Chimie de

Paris (ENSCP) and obtained her Ph.D. in biochem-

istry from the University of Paris. She recently retired

from a position of Emeritus director of Research at

the CNRS where she directed a CNRS-CEA Unit at

the CEA.


Due January 2010

2010. VIII, 420 p. 40 illus., 10 in color.

978-90-481-3766-4 ▶ 119,95 €

N.J. de Mol, M.J. Fischer

Surface Plasmon Resonance


While commercial instruments have expanded the

usage and the related literature has increased, the

quality of surface plasmon resonance (SPR) research

has been hindered by a lack of knowledge of the pro-

cesses that influence the SPR signal. In Surface Plas-

mon Resonance: Methods and Protocols, experts in

the field present a wide variety of applications involv-

ing commercially available SPR instruments. The

heart of the SPR technique is to construct a dedicated

surface for an assay. Protocols describe such surfaces

for many needs, including the study of membrane

bound proteins. Beyond the protocols-based chapters,

the volume also highlights the backgrounds of vital

issues in the use of SPR, including processes occur-

ring within the hydrogel environment of sensors and





8 Biodiversity springer.com

on lipid membrane surfaces as well as the analysis of

kinetic information. Written in the highly successful

Methods in Molecular Biology™ series format, chap-

ters include introductions to their respective topics,

lists of the necessary materials and reagents, step-by-

step, readily reproducible protocols, and notes on

troubleshooting and avoiding known pitfalls. Author-

itative and cutting-edge, Surface Plasmon Resonance:

Methods and Protocols fills a need for well-described,

hands-on SPR experimental protocols and promises

to inspire the adaptation of these techniques to fit the

needs of labs around the world.


Due April 2010



978-1-60761-669-6 ▶ 94,95 €

Biodiversity

J.M. Cock, K. Tessmar-Raible, C. Boyen, F. Viard

Introduction to Marine Genomics

Marine biology has always played an important role

in biological research, being at the origin of many key

advances. To a certain extent, the influence of marine

biology on the biological sciences was overshad-

owed over a period of several years by the remark-

able advances that were made using powerful model

organisms from terrestrial environments. This situa-

tion is now changing again, however, due primarily to

spectacular developments in genomic methodologies

that have significantly accelerated research in a broad

spectrum of marine biology disciplines ranging from

biodiversity to developmental biology to biotechnol-

ogy. The data generated by marine genomics projects

have had an impact on questions as diverse as under-

standing planetary geochemical cycles, the impact of

climate change on marine fauna and flora, the func-

tioning of marine ecosystems, the discovery of new

organisms and novel biomolecules, and investigation

of the evolution of animal developmental complexity.

This book represents the first attempt to document

how genomic technologies are revolutionising these

diverse domains of marine biology. Each chapter of

this book looks at how these technologies are being

employed in a specific domain of marine research and

provides a summary of the major results obtained to

date. The book as a whole provides an overview of

marine genomics as a discipline and represents an

ideal starting point for exploring this rapidly develop-

ing domain.


Due May 2010

2010. Approx. 370 p. (Advances in Marine Genomics, 1)

978-90-481-8616-7 ▶ approx. 149,95 €

Bioinformatics (general)

H. Bang, X.K. Zhou, H.L. Van Epps, M. Mazumdar

Statistical Methods in Molecular

Biology

While there is a wide selection of 'by experts, for

experts’ books in statistics and molecular biology,

there is a distinct need for a book that presents the

basic principles of proper statistical analyses and

progresses to more advanced statistical methods

in response to rapidly developing technologies and

methodologies in the field of molecular biology. Sta-

tistical Methods in Molecular Biology strives to fill

that gap by covering basic and intermediate statis-

tics that are useful for classical molecular biology set-

tings and advanced statistical techniques that can be

used to help solve problems commonly encountered

in modern molecular biology studies, such as super-

vised and unsupervised learning, hidden Markov

models, methods for manipulation and analysis of

high-throughput microarray and proteomic data, and

methods for the synthesis of the available evidences.

This detailed volume offers molecular biologists a

book in a progressive style where basic statistical

methods are introduced and gradually elevated to

an intermediate level, while providing statisticians

knowledge of various biological data generated from

the field of molecular biology, the types of questions

of interest to molecular biologists, and the state-of-

the-art statistical approaches to analyzing the data.

As a volume in the highly successful Methods in

Molecular Biology™ series, this work provides the

kind of meticulous descriptions and implementation

advice for diverse topics that are crucial for getting

optimal results. Comprehensive but convenient, Sta-

tistical Methods in Molecular Biology will aid stu-

dents, scientists, and researchers along the pathway

from beginning strategies to a deeper understand-

ing of these vital systems of data analysis and inter-

pretation within one concise volume. "Here is a

comprehensive book that systematically covers both

basic and advanced statistical topics in molecular

biology, including parametric and nonparametric,

and frequentist and Bayesian methods. I am highly

impressed by the breadth and depth of the applica-

tions. I strongly recommend this book for both statis-

ticians and biologists who need to communicate with

each other in this exciting field of research." - Robert

C. Elston, PhD., Director, Division of Genetic and

Molecular Epidemiology, Case Western Reserve Uni-

versity "An extraordinary exposition of the central

topics of modern molecular biology, presented by

practicing experts who weave together rigorous the-

ory with practical techniques and illustrative exam-

ples." - George C. Newman, MD, PhD, Chairman,

Neurosensory Sciences, Albert Einstein Medical Cen-

ter "I cannot think of anything we need now in trans-

lation research field more than more efficient cross

talk between molecular biology and statistics. This

book is just on target. It fills the gap." - Iman Osman,

MB, BCh, MD, Director, Interdisciplinary Melanoma

Cooperative Program, New York University Langone

Medical Center


Due February 2010

2010. Approx. 550 p. 117 illus. (Methods in Molecular

Biology, 620)

978-1-60761-578-1 ▶ 124,95 €

O. Carugo, F. Eisenhaber

Data Mining Techniques for the

Life Sciences

Whereas getting exact data about living systems and

sophisticated experimental procedures have primar-

ily absorbed the minds of researchers previously, the

development of high-throughput technologies has

caused the weight to increasingly shift to the problem

of interpreting accumulated data in terms of biologi-

cal function and biomolecular mechanisms. In Data

Mining Techniques for the Life Sciences, experts in

the field contribute valuable information about the

sources of information and the techniques used for

"mining" new insights out of databases. Beginning

with a section covering the concepts and structures

of important groups of databases for biomolec-

ular mechanism research, the book then contin-

ues with sections on formal methods for analyzing

biomolecular data and reviews of concepts for ana-

lyzing biomolecular sequence data in context with

other experimental results that can be mapped onto

genomes. As a volume of the highly successful Meth-

ods in Molecular Biology™ series, this work provides

the kind of detailed description and implementa-

tion advice that is crucial for getting optimal results.

Authoritative and easy to reference, Data Mining

Techniques for the Life Sciences seeks to aid students

and researchers in the life sciences who wish to get a




springer.com Biological Microscopy 9

condensed introduction into the vital world of biolog-

ical databases and their many applications.


Due January 2010

2010. XII, 407 p. 89 illus. (Methods in Molecular Biology, 609)

978-1-60327-240-7 ▶ 89,95 €

S.J. Hubbard, A.R. Jones

Proteome Bioinformatics

The field of proteomics moves rapidly, as new meth-

ods, techniques, applications, standards, models and

software appear almost on a daily basis. In Proteome

Bioinformatics, expert researchers explore this ever-

changing field, providing the reader with a mix of

review and methodology chapters which address the

fundamentals of analysis methods, algorithms, data

standards and databases. Chapters include practical

considerations for analyzing database search results,

annotating genomes, speeding up searches, and

responding to specific data processing challenges. As

a volume of the highly successful Methods in Molec-

ular Biology series, this work provides the kind of

detailed description and implementation advice that

is crucial for getting optimal results. Comprehensive

and ground-breaking, Proteome Bioinformatics is an

essential guidebook for the novice and expert alike,

covering topics that address a wide range of data anal-

ysis and management problems.


Due January 2010

2010. Approx. 350 p. 92 illus. (Methods in Molecular Biology,

604)

978-1-60761-443-2 ▶ 89,95 €

R. Matthiesen

Bioinformatics Methods in Clinical

Research

Integrated bioinformatics solutions have become

increasingly valuable in past years, as technologi-

cal advances have allowed researchers to consider

the potential of omics for clinical diagnosis, prog-

nosis, and therapeutic purposes, and as the costs of

such techniques have begun to lessen. In Bioinfor-

matics Methods in Clinical Research, experts exam-

ine the latest developments impacting clinical omics,

and describe in great detail the algorithms that are

currently used in publicly available software tools.

Chapters discuss statistics, algorithms, automated

methods of data retrieval, and experimental consid-

eration in genomics, transcriptomics, proteomics,

and metabolomics. Composed in the highly success-

ful Methods in Molecular Biology™ series format, each

chapter contains a brief introduction, provides practi-

cal examples illustrating methods, results, and conclu-

sions from data mining strategies wherever possible,

and includes a Notes section which shares tips on

troubleshooting and avoiding known pitfalls. Infor-

mative and ground-breaking, Bioinformatics Methods

in Clinical Research establishes a much-needed bridge

between theory and practice, making it an indispens-

able resource for bioinformatics researchers.


Due January 2010

2010. X, 387 p. 63 illus. (Methods in Molecular Biology, 593)

978-1-60327-193-6 ▶ 89,95 €

V. Sintchenko

Infectious Disease Informatics

In this book, Vitali Sintchenko brings together a

collection of state-of-the-art reviews of informatics

applications aiming to improve the diagnosis, preven-

tion, treatment and control of infectious diseases. In

response to the need for computational biology tech-

niques geared towards clinical medicine, this volume

covers the emerging domains of translational bioin-

formatics, genomics enabled decision support, intel-

ligent design of vaccines and antimicrobial drugs as

well as new types of biosurveillance. This book is writ-

ten by a diverse, international group of experts in the

field and provides clinicians, pathologists, biomedi-

cal researchers and informaticians with an essential

resource that offers also a fascinating glimpse into the

future of this dynamic field. Vitali Sintchenko (MBBS,

PhD, FRCPA, FACHI) is a clinical microbiologist and

informatician with the Sydney Medical School, The

University of Sydney, Australia.


Due January 2010

2010. XII, 434 p. 66 illus., 11 in color.

978-1-4419-1326-5 ▶ 149,95 €

Biological Microscopy

Forthcoming

C.D. Geddes

Reviews in Fluorescence 2008

Reviews in Fluorescence 2008, the fifth volume of

the book serial from Springer, serves as a compre-

hensive collection of current trends and emerging

hot topics in the field of fluorescence spectroscopy.

It summarizes the year’s progress in fluorescence

and its applications, with authoritative analytical

reviews specialized enough to be attractive to pro-

fessional researchers, yet also appealing to the wider

audience of scientists in related disciplines of fluo-

rescence. Reviews in Fluorescence offers an essential

reference material for any lab working in the fluores-

cence field and related areas. All academics, bench

scientists, and industry professionals wishing to take

advantage of the latest and greatest in the continu-

ously emerging field of fluorescence will find it an

invaluable resource. Key features: Comprehensive

coverage of the year's hottest and emerging topics.

Chapters authored by known leading figures in the

fluorescence field. Accessible utility in a single vol-

ume reference. New volume publishes annually Each

Reviews in Fluorescence volume will be citable (ISI)

and indexed. Reviews in Fluorescence 2008 topics

include: Imaging Protein Interactions in Living Cells

using the Fluorescent Proteins. Engineering Green

Fluorescent Proteins Using an Expanded Genetic

Code. The use of Fluorescence Anisotropy to Study

the Preferential Orientation of Fluorophores in Orga-

nized Bi-Dimensional Systems. Fluorescence Imaging

of Calcium Loading and Mitochondrial Depolariza-

tion in Cancer Cells Exposed to Heat Stress. Energy

Transfer in Silica Nanoparticles: An Essential Tool

for the Amplification Fluorescence Signals. Geneti-

cally Encoded Fluorescent and Bioluminescent Probes

for Illuminating Cellular Signaling Pathways. Fluo-

rescent Protein FRET Applications. About the Editor:

Dr Chris D. Geddes, Ph.D., Professor, has extensive

experience in fluorescence spectroscopy, particu-

larly in fluorescence sensing and metal-fluorophore

interactions (Metal-Enhanced Fluorescence), pub-

lishing over 190 papers and 18 books. Dr Geddes is

internationally known in fluorescence for his schol-

arly publications and for the development of fluores-

cence-based plasmonics. He is the editor-in-chief of

the Journal of Fluorescence and founding editor of

the Who’s Who in Fluorescence and Annual Reviews

in Fluorescence volumes. In addition, due to the labs

pioneering efforts in the fields of metallic nanopar-

ticle-fluorophore interactions, Dr Geddes launched

the Springer Journal "Plasmonics" in 2005. Dr Ged-

des is Director of the Institute of Fluorescence at the

University of Maryland Biotechnology Institute which

focuses on the nano-bio-technological applications of

fluorescence. Dr Geddes frequently chairs NIH study

sections, is a frequent member of the NIBIB special

emphasis sensing panels and is currently a perma-





10 Cell Biology springer.com

nent member of the NIH EBT study section. http://

theinstituteoffluorescence.com/


Due January 2010

2010. Approx. 490 p. 169 illus., 91 in color. (Reviews in

Fluorescence, 2008)

978-1-4419-0828-5 ▶ 139,95 €

Cell Biology

P. Baumann

G-Quadruplex DNA


Recent work has revealed that stabilizing G-quadru-

plexes in telomeric DNA inhibits telomerase activity,

providing impetus for the development of G-quar-

tet-interacting drugs, while G-quartet-containing

oligonucleotides have been recognized as a potent

class of aptamers effective against STAT3 and other

transcription factors implicated in oncogenesis, prov-

ing these guanine-quartets to be a vital and rich area

for future study. In G-Quadruplex DNA: Methods

and Protocols, experts in the field present a collection

of detailed techniques for studying G-quartet forma-

tion, dynamics, and molecular recognition. Writ-

ten in the highly successful Methods in Molecular

Biology™ series format, chapters include brief intro-

ductions to their respective topics, lists of the nec-

essary materials and reagents, step-by-step, readily


bleshooting and avoiding known pitfalls. Authorita-

tive and cutting-edge, G-Quadruplex DNA: Methods

and Protocols promises to be a useful resource for

those familiar with G-quartets as well as an easy entry

point for those researchers from diverse fields who are

just developing an interest in the exciting implications

of G-quadruplex DNA.


Due January 2010

2010. XII, 276 p. 65 illus., 2 in color. (Methods in Molecular

Biology, 608)

978-1-58829-950-5 ▶ 79,95 €

I.M. Conboy, D.V. Schaffer, M.H. Barcellos-Hoff, S. Li

Protocols for Adult Stem Cells

The study of adult stem cells has surged in recent

years. Because they are responsible for the body’s

natural ability to fight diseases, heal and recover, or

fail and succumb to various maladies, it has become

increasingly important to adapt or devise new meth-

ods to identify and obtain these cells in quantity and

purity for further study. In Protocols for Adult Stem

Cells, expert researchers present a variety of meth-

ods for studying five types of clinically-relevant mam-

malian stems cells: mammary, nerve, skeletal muscle,

endothelial and mesenchymal. Culture techniques

have been optimized for managing the growth and

differentiation of stem cells in vitro; as some stem

cells are pluripotent, often the method is to guide the

fate of such cells among the possible differentiation

fates. Chapters include information that will assist

researchers in obtaining, characterizing and study-

ing these cells or adapting them to the stem cells of

choice. Composed in the highly successful Methods

in Molecular Biology™ series format, each chapter

contains a brief introduction, step-by-step meth-

ods, a list of necessary materials, and a Notes section

which shares tips on troubleshooting and avoiding

known pitfalls. Critical and cutting edge, Protocols for

Adult Stem Cells is an essential guide which provides

groundbreaking and novel techniques certain to rede-

fine the field of stem cell biology.


Due February 2010



978-1-60761-062-5 ▶ 94,95 €

Forthcoming

S. Ding

Cellular Programming and

Reprogramming


Before the therapeutic potential of cell replacement

therapy or the development of therapeutic drugs for

stimulating the body’s own regenerative ability to

repair cells damaged by disease and injury can be

fully realized, control of stem cell fate, immuno-rejec-

tion, and limited cell sources must be overcome. In

Cellular Programming and Reprogramming: Meth-

ods and Protocols, expert researchers cover the most

recent technologies and their related mechanisms

involved in the programming and reprogramming of

cell fate. Written in the highly successful Methods in

Molecular Biology™ series format, chapters include


necessary materials and reagents, step-by-step, labo-

ratory protocols, and notes to highlight tips on trou-

bleshooting and avoiding known pitfalls. Essential

and cutting-edge, Cellular Programming and Repro-

gramming: Methods and Protocols promises to aid

scientists attempting to advance stem cell biology

in order to better treat devastating human diseases,

including cardiovascular disease, neurodegenerative

disease, musculoskeletal disease, diabetes, and cancer.


Due May 2010



978-1-60761-690-0 ▶ 109,95 €

M. Federico

Lentivirus Gene Engineering

Protocols

Second Edition

Since the publication of the first edition, lentivirus

vector-based technologies, through in vitro and in

vivo gene transfer in eukaryotic animal cells, con-

tinue to offer the most promising opportunities for

curing genetic disorders, as well as cancer and infec-

tious diseases. Lentivirus Gene Engineering Proto-

cols, Second Edition reflects the spectacular progress

made in the field with a set of cutting-edge methods

contributed by highly respected scientists. Beginning

with a thorough overview of the most recent lentivirus

developments, the book continues with detailed pro-

tocols including sections on the advances in lentiviral

vector technology, new lentiviral vector applications,

involving transgenic human embryonic stem cells

and fetal gene therapy among other topics, as well as

the invaluable breakthroughs in LV-mediated expres-

sion of microRNAs. Written in the highly successful

Methods in Molecular Biology™ series format, chap-

ters include introductions to their respective subjects,


step, readily reproducible laboratory protocols, and

notes sections, highlighting tips on troubleshooting

and avoiding known pitfalls. Authoritative and timely,

Lentivirus Gene Engineering Protocols, Second Edi-

tion covers the most relevant issues and techniques of

LV-based gene engineering, thus representing a com-

plete theoretical and practical guide for scientists still





springer.com Cell Biology 11

unfamiliar with LV technologies and those who sim-

ply wish to know more about this vital area of study.


Due February 2010


614)

978-1-60761-532-3 ▶ 109,95 €

U. Garg, C.A. Hammett-Stabler

Clinical Applications of Mass

Spectrometry


As mass spectrometric methods now offer a level of

specificity and sensitivity unrealized by spectrophoto-

metric- and immunoassay-based methods, mass spec-

trometry has entered the clinical laboratory where it

is being used for a wide range of applications. In Clin-

ical Applications of Mass Spectrometry: Methods and

Protocols, expert researchers provide detailed step-

by-step procedures for the analysis of number of ana-

lytes of clinical importance. This versatile and expan-

sive volume covers mass spectrometry methods for

analytes including a variety of drugs, hormones, and

metabolic compounds spanning the disciplines of tox-

icology, therapeutic drug monitoring, endocrinol-

ogy, and pediatric metabolism. Written in the highly

successful Methods in Molecular Biology™ series for-

mat, chapters include brief introductions to the ana-

lytes, lists of the necessary materials and reagents,

readily reproducible analytical protocols, and detailed

notes on troubleshooting and avoiding known pit-

falls. Comprehensive and dependable, Clinical Appli-

cations of Mass Spectrometry: Methods and Protocols

offers its readers a wide array of valuable methods for

experienced mass spectrometric labs that are look-

ing to introduce new analyses as well as for those lab-

oratories currently considering the addition of this

resourceful and vital technology.


Due January 2010

2010. XVI, 538 p. 132 illus. (Methods in Molecular Biology,

603)

978-1-60761-458-6 ▶ 89,95 €

T.D. Hewitson, I.A. Darby

Histology Protocols

With much of what we know about the pathogene-

sis of disease coming from the systematic and careful

study of histological material, histology has proven to

be an incredibly valuable area of study. In Histology

Protocols, expert researchers in the field contribute

detailed methods involving the preparation of tissue,

providing an overview of fixation, embedding, and

processing, along with the required techniques for

the retrieval of RNA from histological sections, fol-

lowed by sections on routine and specialist histolog-

ical staining techniques, including immuno-, lectin,

and hybridization histochemistry, histological stain-

ing, as well as specific methods for the in situ identi-

fication of hypoxia and apoptosis, and details on the

advances in imaging and image analysis. Written in

the highly successful Methods in Molecular Biology™

series format, chapters include introductions to their

respective topics, lists of the necessary materials and

reagents, step-by-step, readily reproducible laboratory

protocols, and notes on troubleshooting and avoid-

ing known pitfalls. Authoritative and cutting-edge,

Histology Protocols will provide molecular biologists

with the basic histochemical techniques and histolo-

gists with the molecular techniques necessary to real-

ize the potential of their resource.


Due January 2010

2010. X, 229 p. 71 illus. (Methods in Molecular Biology, 611)

978-1-60327-344-2 ▶ 79,95 €

I. Mus-Veteau

Heterologous Expression of

Membrane Proteins


Membrane proteins play a key role in numerous

pathologies such as cancer, cystic fibrosis, epilepsy,

hyperinsulinism, and Alzheimer’s disease, yet stud-

ies on these and other disorders are hampered by a

lack of information about the proteins involved. In

Heterologous Expression of Membrane Proteins:

Methods and Protocols, expert researchers provide an

overview of the different heterologous expression sys-

tems available to produce these proteins for structural

analysis, helping us to understand how these proteins

function, and additionally, how their functions can be

modified through drug treatment. Chapters examine

membrane protein solubilization, purification, and

instability in solution, and investigate the strategies

that helped to determine the structure of the first het-

erologously expressed mammalian membrane pro-

teins. Composed in the highly successful Methods in

Molecular Biology™ series format, each chapter con-

tains a brief introduction, step-by-step methods, a

list of necessary materials, and a Notes section which

shares tips on troubleshooting and avoiding known

pitfalls. Far-reaching and innovative, Heterologous

Expression of Membrane Proteins: Methods and Pro-

tocols, is an essential guide for novice and experi-

enced researchers alike, providing detailed methods

for existing expression systems alongside cutting-edge

strategies for future use in the field.


Due January 2010

2010. IX, 262 p. 44 illus., 5 in color. (Methods in Molecular

Biology, 601)

978-1-60761-343-5 ▶ 79,95 €

S.H. Naik

Dendritic Cell Protocols

Given the vital importance of immune system

research, the gathering of clear, consistent, and infor-

mative protocols involving the study of dendritic cells

is paramount. Bringing the popular first edition fully

up to date, Dendritic Cell Protocols, Second Edition

presents protocols from experts in the field that cover

the basics and more complex forays into the explo-

ration of DC development and function, both in mice

and humans. The first section of the volume involving

humans explores topics such as the isolation of blood

DC subtypes, primary skin Langerhans cells, and the

generation of gene-manipulated human DCs with

the inclusion of more clinically relevant methods as

well, while the second section involving rodent mod-

els delves into DC and precursor generation in vitro,

isolation ex vivo, disease models, as well as DC func-

tions and properties. Written in the highly successful

Methods in Molecular Biology™ series style, chap-

ters include introductions to their respective subjects,



notes on troubleshooting and avoiding known pitfalls.

Comprehensive and cutting-edge, Dendritic Cell Pro-

tocols, Second Edition aims to become a bench-side





12 Cell Biology springer.com

handbook for both beginners and experts in the field

of DC research and a long-term reference for some of

the most popular methods put forward by those who

lead the field.


Due January 2010

2010. XVIII, 446 p. 66 illus., 6 in color. (Methods in Molecular

Biology, 595)

978-1-60761-420-3 ▶ 89,95 €

A. Sharon

Molecular and Cell Biology

Methods for Fungi

With the development of fungal transformation sys-

tems and the deciphering of an increasing number of

fungal genomes, this diverse clade of heterotrophic

eukaryotic organisms has proven to be ideal for

molecular work and highly serviceable as model sys-

tems to study basic processes with results that are

applicable to many organisms, including humans.

In Molecular and Cell Biology Methods for Fungi,

experts in the field provide an up-to-date set of prac-

tical protocols covering a range of frequently used

methods used to study molecular and cellular aspects

of fungal biology. The included classical protocols

such as transformation systems and traditional pro-

tein analysis methods, which have been widely used

for many years, alongside the most advanced tech-

niques such as genome amplification, whole genome

knockout methods, and sophisticated in vivo imaging

techniques will prove to be easily adaptable and useful

in a wide range of species. Written in the highly suc-

cessful Methods in Molecular Biology™ series format,

chapters include introductions to their respective top-

ics, lists of the necessary materials and reagents, step-

by-step, readily reproducible laboratory protocols,

and notes on troubleshooting and avoiding known

pitfalls. Comprehensive and up-to-date, Molecular

and Cell Biology Methods for Fungi seeks to provide

cutting-edge techniques in order to aid both experi-

enced fungal research laboratories as well as those that

are interested in using fungi as hosts to study their

favorite genes.


Due May 2010



978-1-60761-610-8 ▶ 94,95 €

M. Soloviev

Peptidomics


Despite being known and studied for years, peptides

have never before attracted enough attention to neces-

sitate the invention of the term "peptidomics" in order

to specify the study of the complement of peptides

from a cell, organelle, tissue or organism. In Pep-

tidomics: Methods and Protocols, expert researchers

present a comprehensive range of analytical tech-

niques for the analysis of the peptide contents of com-

plex biological samples with an emphasis often on

higher throughput techniques, suitable for the anal-

ysis of large numbers of peptides typically present in

the peptidomes. Encompassing a number of species

ranging from bacteria to man, the methods presented

intensively cover topics such as organism handling,

tissue and organ dissection, cellular and subcellular

fractionation, peptide extraction, fractionation and

purification, structural characterization, molecular

cloning, and sequence analysis. Written in the highly

successful Methods in Molecular Biology™ series for-

mat, chapters include introductions to their respective

topics, lists of the necessary materials and reagents,

step-by-step, readily reproducible laboratory pro-

tocols, and notes on troubleshooting and avoiding

known pitfalls. Comprehensive and cutting-edge,

Peptidomics: Methods and Protocols brings this

ten year old field fully up-to-date in order to inspire

novices and experts alike with the easy-to-follow prac-

tical advice needed to set up and carry out analysis of

the peptide contents of complex biological samples.


Due February 2010


615)

978-1-60761-534-7 ▶ 89,95 €

Z. Wang, B. Yang

MicroRNA Expression Detection

Methods

This book provides comprehensive descriptions of the

innovative strategies and methodologies for detect-

ing miRNA expression, their application in miRNA

research and their potential as tools for clinical diag-

nosis and prognosis. It begins with the introduction of

the overall concept and strategies of miRNA expres-

sion detection methods emphasizing the need of a

wide variety of these methods to suit specific require-

ments for research and clinical examination in labora-

tories. In the following, each single chapter focuses on

an independent, unique method of miRNA detection

and is divided into five subsections: summary, intro-

duction, protocol (including materials, instrument,

reagent, and procedure), application and limitation,

and reference. The development of the technique, the

ideas behind it and the mechanisms underlying the

method are given in the introduction of each chap-

ter. The step-by-step protocols are detailed in the pro-

tocol section. Then, the applications and limitations

of the methods are discussed. Finally, the literature

citations are listed in reference section. Schematic dia-

grams are included where needed and appropriate

for better illustrating the principle of the methodolo-

gies. In addition, flowcharts are also provided to out-

line the protocols for each of the miRNA expression

detection methods. This book is aimed to target both

researchers involved in miRNA research of any fields

in universities and research institutions and medical

practitioners who are interested in developing or uti-

lizing miRNA profiling as a complementary and an

alternative strategy for clinical diagnosis of human

disease.


Due January 2010

2010. Approx. 450 p.

978-3-642-04927-9 ▶ 149,95 €

Forthcoming

A. Ward, D. Tosh

Mouse Cell Culture


Cultured cells have combined accessibility and the

ability to expand a homogeneous cell population from

a relatively limited source, thus opening up a wealth

of possibilities for researchers. In Mouse Cell Cul-

ture: Methods and Protocols, expert researchers pro-

vide a number of methods for the culture of a wide

range of specific cells and tissues isolated from the key

genetic model of the fetal or adult mouse. Including





springer.com Ecology (general) 13

protocols for the explant of fetal tissues and stem cells

that allow developmental processes to be followed ex

vivo as well as protocols for the culture of isolated cell

types that allow for the study of relatively homoge-

neous cell populations, this volume brings together

a selection of the most current methods in order to

make them available in one convenient source. Writ-

ten in the highly successful Methods in Molecular

Biology™ series format, chapters include introductions

to their respective topics, lists of the necessary mate-

rials and reagents, step-by-step, readily reproducible

laboratory protocols, and notes on troubleshooting

and avoiding known pitfalls. Practical and authori-

tative, Mouse Cell Culture: Methods and Protocols

serves as an immediately applicable springboard for

the development of new tissue culture methods in

order to advance the study and treatment of human

disorders.


Due May 2010



978-1-58829-772-3 ▶ 94,95 €

V. Weissig

Liposomes

Methods and Protocols, Volume 1:

Pharmaceutical Nanocarriers

With nearly one hundred years of intensive study,

lipids have proven to be a vital and ever-more-

promising area of cell biological research. In Lipo-

somes: Methods and Protocols, leading experts in

the related fields explore cutting-edge experimen-

tal methods involving all aspects of lipids as essential

components of the cell membrane. Volume 1: Phar-

maceutical Nanocarriers focuses on the state-of-the-

art aspects of developing liposome-based nanoscale

drug delivery techniques, delving into the depths of

the emerging field of pharmaceutical and biomedical

nanotechnology. As a volume in the highly success-

ful Methods in Molecular Biology™ series, the chap-

ters include introductions to their respective topics,



notes on troubleshooting and avoiding known pitfalls.

Comprehensive and authoritative, Liposomes: Meth-

ods and Protocols promises to be an essential source

of practical know-how for every investigator, young

and seasoned alike, whose research area involves in

one way or another phospholipids, glycolipids, or

cholesterol.


Due February 2010



978-1-60327-359-6 ▶ 89,95 €

V. Weissig

Liposomes

Methods and Protocols, Volume 2: Biological

Membrane Models

With nearly one hundred years of intensive study,

lipids have proven to be a vital and ever-more-

promising area of cell biological research. In Lipo-

somes: Methods and Protocols, leading experts in

the related fields explore cutting-edge experimen-

tal methods involving all aspects of lipids as essential

components of the cell membrane. Volume 2: Bio-

logical Membrane Models focuses on detailed meth-

ods for the use of liposomes in studying a variety of

biochemical and biophysical membrane phenomena

concomitant with chapters describing a great palette

of state-of-the-art analytical technologies. As a vol-

ume in the highly successful Methods in Molecular

Biology™ series, the chapters include introductions to

their respective topics, lists of the necessary materials

and reagents, step-by-step, readily reproducible lab-

oratory protocols, and notes on troubleshooting and

avoiding known pitfalls. Comprehensive and author-

itative, Liposomes: Methods and Protocols promises

to be an essential source of practical know-how for

every investigator, young and seasoned alike, whose

research area involves in one way or another phos-

pholipids, glycolipids, or cholesterol.


Due February 2010



978-1-60761-446-3 ▶ 89,95 €

Ecology (general)

Forthcoming

C.A. Edwards, P. Hendrix, N. Arancon

Biology and Ecology of

Earthworms

This 4th edition updates the latest research on earth-

worms. More than 3,000 species of earthworm exist

in the world. They are considered to be an impor-

tant ally in advancing environmental and biomedical

research. Earthworms play an important role in forest

or agricultural ecosystems and play an increasing role

in biomedical issues. Earthworms are critical to the

environment because they consume huge quantities of

decomposed litter, manure, and other organic matter

deposited on soil -- helping to convert it into rich top-

soil Earthworms can also help reduce soil compaction,

improve permeability--thus providing channels for

root growth, water infiltration, and gas exchange.

Earthworms are also important animals for the assess-

ment of the toxicity of chemicals, such as herbicides

and pesticides, which are deliberately released into the

environment. Earthworms are superb ‘barometers' or

‘sentinels' providing an early warning of deterioration

in soil quality.


Due May 2010

2010. Approx. 530 p. 60 illus.

978-0-387-74942-6 ▶ approx. 76,20 €

Forthcoming

C. Fang, B. Li, Y. Luo, J. Chen, J. Chen

Ecology in the Yangtze River

Estuary

The Yangtze River estuary is a system where geologi-

cal, biological, and socioeconomic processes actively

interplay. The Yangtze River carries about 5 billion

tons of sediment to the estuary from upstream each

year, providing rich substrates for biological activi-

ties and alluvial processes. An exotic plant species,

Spartina alterniflora was intentionally introduced to

the region in 1979, and has aggressively invaded the

Yangtze River estuary and coastal China. The biolog-

ical invasion alters plant and animal biodiversity and

ecosystem processes. In addition, the Yangtze River

estuary is close to Shanghai, one of the most econom-

ically active cities in China and the world. Fast eco-

nomic development and social transformation exert

great pressure to exploit resources in the estuary. In

the last few decades, scientists from several leading

universities in China have conducted research on

many of geological, biological, and socioeconomic

processes. An increasing number of papers have been

published in international journals. This volume com-

prehensively synthesizes the lessons learned from

various groups. This text not only provides a new

example of ecosystem studies on estuary systems, but

will also serve as a milestone to promote the man-

agement of this important region that will produce

global impacts. Moreover, the book can be used as

a reference book for ecological research in estuarine





14 Entomology springer.com

ecosystems of major rivers, such as the Mississippi

and Amazon Rivers.


Due May 2010

2010. Approx. 495 p. 40 illus. (Ecological Studies, 1001)

978-0-387-76769-7 ▶ approx. 114,75 €

Entomology

J. Amendt, M.L. Goff, C.P. Campobasso, M. Grassberger

Current Concepts in Forensic

Entomology

Twenty years ago the use of entomology in a crime

scene investigation was considered bizarre, despite the

solid scientific background and documented historical

applications. Today, the use of insect evidence is an

accepted sub-discipline in modern forensic science.

Nevertheless, forensic entomology is still growing

and remains a living scientific discipline with many

branches. The present book highlights this diversity

by collecting contributions dealing with novel aspects,

for example, marine biology, chemical ecology and

acarology, as well as the basic disciplines like ento-

motoxiciology and decomposition. It also offers keys

for immature insects, discussions of important pit-

falls and introductions to the statistical evaluation

of data sets. Many topics are covered in depth for

the first time. All the authors are leading experts in

their respective fields of research. Their chapters show

directions for future research for both new and vet-

eran forensic entomologists. Undoubtedly, forensic

entomology will continue to grow and attract new

professionals, students, as well as interested observers.

This book is written for all of them.


Due January 2010

2010. Approx. 350 p.

978-1-4020-9683-9 ▶ 149,95 €

Forthcoming

H.E. Roy, F.E. Vega, D. Chandler, M.S. Goettel, J.K. Pell, E.

Wajnberg

The Ecology of Fungal

Entomopathogens

Understanding of the ecology of fungal ento-

mopathogens has vastly increased since the early

1800’s, but remains challenging. The often complex

interactions between pathogen and host are being

unravelled through eloquent research and the impor-

tance of the often subtle interactions, in determining

the success or failure of biological control, cannot be

underplayed. The realm of ecology is vast and deci-

phering insect-fungal pathogen interactions within

an ecological context will take us on voyages beyond

our imagination. This book brings together the work

of renowned scientists to provide a synthesis of recent

research on the ecology of fungal entomopathogens

exploring host-pathogen dynamics from the con-

text of biological control and beyond. Dr. Helen Roy

leads zoological research in the Biological Records

Centre at the NERC Centre for Ecology & Hydrol-

ogy, UK. The focus of her research is insect com-

munity interactions with particular emphasis on the

effects of environmental change. She has been work-

ing on the ecological interactions between fungal

entomopathogens and their hosts for 15 years; this

continues to be a source of fascination. She has been

an associate editor of BioControl since 2006. Dr. Dave

Chandler is an insect pathologist at the University

of Warwick, UK. He has studied entomopathogenic

fungi for just over 20 years. He has particular inter-

ests in entomopathogenic fungi as biocontrol agents

of horticultural crops, fungal physiology and ecol-

ogy, and the pathogens of honeybees. Dr. Mark Goet-

tel is an insect pathologist at the Lethbridge Research

Centre of Agriculture & Agri-Food Canada, special-

izing in the development of fungal entomopathogens

as microbial control agents of insects. In addition to

this research, he has been extensively involved in the

review and revision of the regulations for registration

of microbial control agents and has addressed regu-

latory and safety issues at the international level. He

is currently President of the Society for Invertebrate

Pathology and has been Editor-in-Chief of Biocon-

trol Science & Technology since 2000. Dr. Judith K.

Pell heads the Insect Pathology Group in the Depart-

ment for Plant and Invertebrate Ecology at Rotham-

sted Research, UK. She leads research on the ecology

of fungal entomopathogens, to elucidate their role in

population regulation and community structure and

to inform biological control strategies. Specifically:

intraguild interactions; the relationships between

guild diversity, habitat diversity and ecosystem func-

tion; pathogen-induced host behavioural change. Dr.

Eric Wajnberg is a population biologist specialising

in behavioural ecology, statistical modelling and pop-

ulation genetics. He is also an expert in biological

control, with more than 20 years experience of work-

ing with insect parasitoids. He has been the Editor in

Chief of BioControl since 2006. Dr. Fernando E. Vega

is an entomologist with the United States Depart-

ment of Agriculture, Agricultural Research Service, in

Beltsville, Maryland, USA. He conducts research on

biological methods to control the coffee berry borer,

the most important insect pest of coffee throughout

the world. He is co-editor, with Meredith Blackwell,

of Insect-Fungal Associations: Ecology and Evolution,

published by Oxford University Press in 2005, and

serves as an Editorial Board Member for Fungal Ecol-

ogy.


Due January 2010

2010. Approx. 250 p.

978-90-481-3965-1 ▶ approx. 90,00 €

Enzymology

J. Yon-Kahn, G. Hervé

Molecular and Cellular

Enzymology

Molecular and Cellular Enzymology addresses not

only experienced enzymologists but also students,

teachers and academic and industrial researchers who

are confronted with enzymological problems during

their fundamental or applied research. In this field

is an urgent need for training in order to meet the

requirements of both research and industrial endeav-

ours. This book consists of several levels. Practical

aspects and elementary explanations are given for the

benefit of non-specialists’ and students’ understand-

ing. In order to facilitate the task of students, two

typographies have been adopted. The main text corre-

sponds to basic knowledge, whereas text in a smaller

font provides more specialised information. Spe-

cialists will also find topics more deeply expounded

with the principal bibliographic references cited. The

bibliography, however, is not exhaustive; the choice

includes general books and review articles as well as

some specialised articles. In this book, for the first

time, the different molecular and cellular aspects of

enzymology are presented together. Until now, there

has been no book available in which these different

aspects are treated in the same volume. In addition,

besides the theoretical developments, this book pro-

vides a wealth of practical information for experimen-

talists.


Due January 2010

2010. XII, 353 p. 290 illus., 47 in color. In 2 volumes, not

available separately.

978-3-642-01227-3 ▶ 239,00 €

Evolutionary Biology

Forthcoming

K. D'Aout, E.E. Vereecke

Primate Locomotion:

Linking Filed and Laboratory Research

Primate locomotion has typically been studied from

two points of view. Laboratory-based researchers have

focused on aspects like biomechanics and energet-

ics, whereas field-based researchers have focused on

(locomotor) behaviour and ecology. Unfortunately,





springer.com Fungus Genetics 15

to date, there is relatively little scientific exchange

between both groups. With a book, which will be

the result of a symposium on the 2008 Meeting of

the International Primatological Society in Edin-

burgh, we would like to bring together laboratory and

field-based primate locomotion studies. We are con-

vinced this will be beneficial for both research lines.

For example, biomechanists might wonder how fre-

quently the locomotor style they study in the lab actu-

ally occurs in nature, and field workers might use

calculated costs of locomotion to understand why cer-

tain locomotor behaviours are favoured under specific

conditions. Thus, on the one hand, an established link

between both groups may help interpret the results by

using each other’s findings. On the other hand, recent

technological advances (e.g. portable high-speed cam-

eras) make it possible to bridge the gap between lab-

based and field-based research by actually collect-

ing biomechanical data in situ. Again, communica-

tion between both groups is necessary to identify the

specific needs and start up achievable and success-

ful research projects in the field. In order to gener-

ate a wide interest, we have invited biomechanists,

ecologists, and field-based researchers who combine

both disciplines, and we hope their combined con-

tributions will facilitate lasting cooperation between

the mentioned disciplines and stimulate innovative

research in Primatology. We are convinced that the

most appropriate format to publish the different sym-

posium contributions is a conference volume within

an existing book series. Firstly, the chapters will not

only contain new data but will also review existing

data and elaborate on potential future work – more

so than can be done in a journal article. Secondly,

the combination of chapters will form an entity that

is more valuable than the sum of the separate chap-

ters and therefore they need to be presented together.

Lastly, this volume will benefit from the typically long

"shelf life" of a book in a renowned series, allowing it

to be used as reference book for both researchers and

students.


Due April 2010

2010. Approx. 250 p. 90 illus. (Developments in Primatology:

Progress and Prospects, )

978-1-4419-1419-4 ▶ approx. 99,95 €

Fungus Genetics

Y. Gherbawy, K. Voigt

Molecular Identification of Fungi

Fungi enjoy great popularity in pharmaceutical,

agricultural, and biotechnological applications.

Recent advances in the decipherment of whole fun-

gal genomes promise an acceleration of these trends.

This timely book links scientists from different parts

of the world who are interested in the molecular iden-

tification of fungi combined with the exploration of

the fungal biodiversity in different ecosystems. It pro-

vides a compendium for scientists who rely on a rapid

and reliable detection of fungal specimens in environ-

mental as well as clinical resources in order to ensure

the benefit of industrial and clinical applications.

Chapters focus on the opportunities and limits of the

molecular marker-mediated identification of fungi.

Various methods, procedures and strategies are out-

lined. Furthermore, the book offers an update of the

current progress in the development of fungal molec-

ular techniques, and draws attention to potential and

associated problems, as well as integrating theory and

practice.


Due March 2010

2010. Approx. 520 p. 87 illus., 39 in color.

978-3-642-05041-1 ▶ 169,95 €

Invertebrates

Forthcoming

P.A. Stansly, S.E. Naranjo

Bemisia: Bionomics and

Management of a Global Pest

Bemisia tabaci (Gennedius) has distinguished itself

from the more than 1000 whitefly species in the world

by it adaptability, persistence and potential to damage

a wide range of agricultural and horticultural crops

in all six of the world’s inhabited continents. B. tabaci

inflicts plant damage through direct feeding, induce-

ment of plant disorders, vectoring of plant viruses and

excretion of honeydew. This book collates multiple

aspects of the pest ranging from basic to applied sci-

ence and molecular to landscape levels of investiga-

tion. Experts in multiple disciplines provide broad,

but detailed summaries and discussion of taxonomy,

genetics, anatomy, morphology, physiology, behavior,

ecology, symbiotic relationships, virus vector associa-

tions and various tactics for integrated management

of this pest insect. The book is focused primarily on

progress during the last 10-15 years and is directed

at workers in the field as well as the informed profes-

sional who may not necessarily specialize in whitefly

research. The book is unique in providing broad cov-

erage in relatively few chapters by recognized experts

that highlight the state-of-the-art in our understand-

ing of this fascinating but troublesome cosmopolitan

pest.


Due March 2010

2010. Approx. 350 p.

978-90-481-2459-6 ▶ approx. 149,95 €

Life Sciences (general)

Forthcoming

D. Favareau

Essential Readings in Biosemiotics

Anthology and Commentary

Synthesizing the findings from a wide range of disci-

plines – from biology and anthropology to philosophy

and linguistics – the emerging field of Biosemiotics

explores the highly complex phenomenon of sign

processing in living systems. Seeking to advance a

naturalistic understanding of the nature and evolu-

tion of sign processes and meaning, contemporary

biosemiotic research and theory holds deep implica-

tions for all those interested in the origins and evo-

lution of life and language, as well as those exploring

related issues such as evolutionary psychology, artifi-

cial intelligence and the rich diversity of non-verbal

human and animal communication processes. Don-

ald Favareau’s Essential Readings in Biosemiotics has

been designed to provide a single-source overview of

the major works informing this new interdiscipline,

including both historical and analytical commentary

on each of the texts presented. The first of its kind,

this book will provide a primary text for students in

biosemiotics, as well as a valuable resource to biosci-

entists and semioticians interested in this emerging

new discipline. Moreover, because of its inherently

interdisciplinary nature and its focus on the ‘big ques-

tions’ of cognition, meaning and evolutionary biology,

this volume should be of interest to anyone working

in the fields of cognitive science, theoretical biology,

philosophy of mind, evolutionary psychology, com-

munication studies and the history of science.


Due January 2010

2010. Approx. 870 p. (Biosemiotics, 3)

978-1-4020-9649-5 ▶ approx. 199,95 €





16 Microbial Genetics and Genomics springer.com

Forthcoming

J. Seckbach, R. Einav, A. Israel

Seaweeds and their Role in

Globally Changing Environments

Global warming is accelerating faster than the abil-

ity for natural repair, and environmental stresses are

damaging ecosystems, all affecting physical and bio-

logical systems on Earth. A new Nasa-led study shows

that human activity has caused climate changes result-

ing in permafrost thawing, acid rain, and lower pro-

ductivity in lakes as well as increased emissions of

greenhouse gases, including CO2, N20, CH4, CF3,

and CFC. Marine plants play a vital role in maintain-

ing the balance of marine environments, while serv-

ing as a source of food for humankind and important

chemical compounds. Microalgae and seaweed have

enormous potential for reducing global warming and

climate change. During photosynthesis algae grow,

draw CO2 from the atmosphere, release oxygen, and

produce solar biofuel. Experts in the life of marine

plant ecosystems in globally changing environments

contributed chapters to this book. The target read-

ers are phycologists, ecologists, atmospheric scholars,

conservationists, environmentalists, and ecologically

aware laymen.


Due February 2010

2010. Approx. 600 p. (Cellular Origin, Life in Extreme

Habitats and Astrobiology, 15)

978-90-481-8568-9 ▶ approx. 169,95 €

Forthcoming

J. Seckbach, D.J. Chapman

Red Algae in the Genomic Age

This volume covers the modern biology and the

speciation of the red algae (Rhodophyta) from uni-

cellular Cyanidia up to macrocellular sea weeds. A

team of peer reviewers has reviewed all chapters. The

chapters describe a range of topics from cave algae

from Atacama, Chile, to genomes of red algae. Some

chapters deal with the carbohydrates, physiological

mechanisms, and realtionship between red algae and

neurodegenerative disease. Other chapters deal with

organellar - nuclear genes and taxonomic revision.

Emphasis is placed upon the rhodophytan chloro-

plast, its origin, evolution, division machinery and

pigmentation. The reader will find in this book lots of

new information on the red algae.


Due January 2010



978-90-481-3794-7 ▶ approx. 149,95 €

Forthcoming

J. Seckbach, A. Oren

Microbial Mats

Modern and Ancient Microorganisms in

Stratified Systems

This book provides information about microbial

mats, from early fossils to modern mats located

in marine and terrestrial environments. Microbial

mats – layered biofilms containing different types

of cells – are most complex systems in which rep-

resentatives of various groups of organisms are

found together. Among them are cyanobacteria

and eukaryotic phototrophs, aerobic heterotrophic

and chemoautotrophic bacteria, protozoa, anoxy-

genic photosynthetic bacteria, and other types of

microorganisms.These mats are perfect models for

biogeochemical processes, such as the cycles of chem-

ical elements, in which a variety of microorganisms

cooperate and interact in complex ways. They are

often found under extreme conditions and their study

contributes to our understanding of extremophilic

life. Moreover, microbial mats are models for Precam-

brian stromatolites; the study of modern microbial

mats may provide information on the processes that

may have occurred on Earth when prokaryotic life

began to spread.


Due February 2010



978-90-481-3798-5 ▶ approx. 149,95 €

Microbial Genetics and

Genomics

S.K. Lal

Molecular Biology of the SARS-

Coronavirus

The SARS outbreak in 2002 caused unprecedented

devastation and exhibited unusually high rates of

morbidity and mortality. For the SARS coronavirus,

the transmission vehicle was man. What added to the

spread was man’s convenient, rapid and affordable

ways of travel that caused the virus to spread glob-

ally in a short span of time. The SARS coronavirus

jumped the species barrier, similar to many recent

zoonotic diseases – avian flu, swine flu, Nipah and

encephalitis virus. It is extremely important for us to

understand the enemy before it strikes again in order

to be able to combat such outbreaks as and when they

occur. Molecular mechanisms that the virus exploits

within its host and that result in infection and patho-

genesis are the key to being able to block its trans-

mission cycle. In this book, leading scientists from

around the globe have discussed molecular aspects of

viral entry, replication, viral gene expression, patho-

genesis and host immune response against the SARS

coronavirus.


Due January 2010

2010. XVI, 300 p.

978-3-642-03682-8 ▶ 149,95 €

Microbiology (general)

A.W. Artenstein

Vaccines: A Biography

Recounting the social, cultural, and scientific his-

tory of vaccines, Vaccines: A Biography traces the

lineage—the ‘biography’—of individual vaccines,

originating with deeply rooted medical problems, fol-

lowing ideas as they are conceived and developed,

leading eventually to practical, preventive solutions to

major public health problems in society. Yet these are

not ‘biographies’ in the traditional sense; they do not

trace an individual’s growth and development. These

are epic stories of discovery, of risk-takers. They have

all the trappings of fiction: strong protagonists who

succeed against sometimes great odds, interpersonal

conflicts, deceit, political intrigue, ethical dilemmas,

and dramatic, if not staged events. They are set in the

major centers of Europe and the United States, on

farms and in slums, and in exotic venues from Cal-

cutta to French Indochina to Cairo to Panama. They

occur in the halls of academia, research laboratories,

the chambers of government, and on the battlefields

of war. At its core, Vaccine: A Biography is the his-

tory of individuals advancing medical science, in the

words of the famous physical scientist Isaac Newton,

"by standing on the shoulders of giants".


Due January 2010

2010. XXI, 401 p. 84 illus., 2 in color.

978-1-4419-1107-0 ▶ 149,95 €






springer.com Neurobiology 17

J.F. Atkins, R.F. Gesteland

Recoding: Expansion of Decoding

Rules Enriches Gene Expression

The dynamic nature of decoding the information in

messenger RNA was unanticipated at the time the

genetic code was first deciphered. We now know

that both the meaning of individual codons and the

framing of the readout process can be modified by

information in specific messenger RNAs. This book

describes this "Recoding" phenomenon, revealing

the diversity of an additional layer of information in

mRNAs that serves to enrich the expression of genes.

Knowledge of recoding is essential for understanding

the organization and expression of genes in viruses

and all organisms ranging from bacteria to archeae to

plants to humans, making Recoding pertinent to all

biological sciences.


Due January 2010

2010. XX, 466 p. 156 illus., 63 in color. (Nucleic Acids and


978-0-387-89381-5 ▶ 159,95 €

Neurobiology

Forthcoming

T. Hökfelt

Galanin

Galanin is a neuropeptide which is found in the cen-

tral and peripheral nervous system. It is involved in a

number of physiological processes such as regulation

of food intake, metabolism and reproduction, regula-

tion of neurotransmitter and hormone release, noci-

ception, intestinal motility and secretion, and more

recently in nervous system development and response

to injury. The wide diversity of actions is mediated by

several galanin receptor subtypes. This book gives an

overview of the current state of galanin research and

shows how the identification, isolation and charac-

terization of this peptide was brought about and how

the functionality of galanin was revealed as the phar-

macological tools to dissect galaninergic mechanisms

were developed.


Due June 2010

2010. Approx. 300 p. (Experientia Supplementum, 102)

978-3-0346-0227-3 ▶ approx. 149,00 €

Plant Anatomy / Development

Forthcoming

E.C. Pua, M.R. Davey

Plant Developmental Biology -

Biotechnological Perspectives

This work, comprising two volumes, reviews recent

advances in plant developmental biology and explores

the possibility of their biotechnological applica-

tions. The work is a key reference for plant breeders,

researchers and graduate students.


Due March 2010

2010.

978-3-642-04877-7 ▶ 249,00 €

Plant Breeding / Biotechnology

F. Kempken, C. Jung

Genetic Modification of Plants

Agriculture, Horticulture and Forestry

Today´s agriculture faces new and difficult challenges.

With modern methods widely applied, it is com-

monly believed that genetic crop improvement is a

key for increasing yields. In spite of the discussion

about the safety of genetically modified (GM) crops

that is still raging in the European Union where the

take-up of the new technology is more limited, the

cultivation of GM plants and crops has exploded all

over the world. Conceived with the aim of sorting

fact from fiction over GM crops, this volume brings

together the knowledge of 30 specialists in the field of

transgenic plants. It covers the generation and detec-

tion of these plants as well as the genetic traits con-

ferred on transgenic plants. In addition, the book

looks at a wide variety of crops, ornamental plants

and tree species that are subject to genetic modifica-

tions, assessing the risks involved in genetic modifi-

cation as well as the potential economic benefits of

the technology in specific cases. The book’s structure,

with fully cross-referenced chapters, gives readers a

quick access to specific topics, whether that is detailed

and comprehensive data on particular species of orna-

mentals, or coverage of the socioeconomic implica-

tions of GM technology. With an increasing demand

for bioenergy, and the necessary higher yields relying

on wider genetic variation, this book supplies all the

technical details required to move forward to a new

era in agriculture.


Due January 2010

2010. XX, 600 p. 34 illus., 10 in color. (Biotechnology in

Agriculture and Forestry, 64)

978-3-642-02390-3 ▶ 249,00 €

C. Kole, C.H. Michler, A.G. Abbott, T.C. Hall

Transgenic Crop Plants

Volume 1: Principles and Development

Development of transgenic crop plants, their utiliza-

tion for improved agriculture, health, ecology and

environment and their socio-political impacts are

currently important fields in education, research and

industries and also of interest to policy makers, social

activists and regulatory and funding agencies. This

work prepared with a class-room approach on this

multidisciplinary subject will fill an existing gap and

meet the requirements of such a broad section of

readers. Volume 1 with ten chapters contributed by

31 eminent scientists from nine countries deliberates

on the basic concepts, strategies and tools for devel-

opment of transgenic crop plants, including topics

such as: explants used for the generation of transgenic

plants, gene transfer methods, organelle transfor-

mation, selection and screening strategies, expres-

sion and stability of transgenes, silencing undesirable

genes, transgene integration, biosynthesis and bio-

transformation and metabolic engineering of path-

ways and gene discovery.


Due January 2010

2010. XXII, 314 p.

978-3-642-04808-1 ▶ 149,95 €






18 Plant Genetics and Genomics springer.com

C. Kole, C.H. Michler, A.G. Abbott, T.C. Hall

Transgenic Crop Plants

Volume 2: Utilization and Biosafety

Development of transgenic crop plants, their utiliza-

tion for improved agriculture, health, ecology and

environment and their socio-political impacts are

currently important fields in education, research and

industries and also of interest to policy makers, social

activists and regulatory and funding agencies. This

work prepared with a class-room approach on this

multidisciplinary subject will fill an existing gap and

meet the requirements of such a broad section of

readers. Volume 2 with 13 chapters contributed by

41 eminent scientists from nine countries deliberates

on the utilization of transgenic crops for resistance to

herbicides, biotic stress and abiotic stress, manipula-

tion of developmental traits, production of biofuel,

biopharmaceuticals and algal bioproducts, ameliora-

tion of ecology and environment and fostering func-

tional genomics as well as on regulations and steps

for commercialization, patent and IPR issues, and

compliance to concerns and compulsions of utilizing

transgenic plants.


Due January 2010

2010. XXII, 494 p.

978-3-642-04811-1 ▶ 149,95 €

E.C. Pua, M.R. Davey

Plant Developmental Biology -

Biotechnological Perspectives

Volume 2

Understanding the mechanisms whereby plant devel-

opment is regulated is crucial for crop improvement

using genetic engineering. This work, comprising two

volumes, reviews recent advances in plant develop-

mental biology and explores the possibility of their

practical applications from biotechnological perspec-

tives. Volume 1 deals with the plant model and its life

cycle. Topics include the formation of shoots, roots,

flowers and gametes, pollen germination, fertiliza-

tion, fruit development and ripening, seed develop-

ment, dormancy and germination, apomixis, male

sterility and self-incompatibility. Volume 2 focuses on

development-related areas, including tissue culture

(somatic embryogenesis, microspore embryogene-

sis, somaclonal variation), plant processes (photosyn-

thesis, seed maturation and seed proteins, fatty acids,

vitamins, alkaloids, flower pigments and scent), sig-

nalling (amino compound-containing lipids, auxins,

cytokinins and light), and molecular genetics of devel-

opmental regulation (RNA silencing, DNA methy-

lation, epigenetics, activation tagging, homologous

recombination and synthetic promoter engineer-

ing). This work is a key reference for plant breed-

ers, researchers and graduate students in the fields of

plant biotechnology, agronomy, horticulture, genetics

and functional genomics, and cell and molecular biol-

ogy.


Due March 2010


978-3-642-04669-8 ▶ 149,95 €

U.B. Zehr

Cotton

Biotechnological Advances

The growing global population poses the challenge

to the scientific community of doubling or tripling

the food, feed and fiber production by the year 2050.

Biotechnology can make a significant contribution

to this effort. This volume reviews the use of biotech-

nology in cotton, which is the leading plant fiber crop

worldwide and grown commercially in more than 50

countries. Renowned experts highlight the success of

Bt cotton, the introduction of second and third gen-

eration traits and the impact at all levels of farming.

Furthermore, the molecular advances being made in

cotton biotechnology and the potential traits that will

come to market in the next decade are described in

detail.


Due February 2010

2010. X, 230 p. 30 illus., 13 in color. (Biotechnology in

Agriculture and Forestry, 65)

978-3-642-04795-4 ▶ 149,95 €

Plant Genetics and Genomics

S. Jansson, R.P. Bhalerao, A.T. Groover

Genetics and Genomics of Populus

Trees are truly amazing! Woody species underpin

vital terrestrial ecosystems, present a complex array

of evolutionary novelties, and provide essential ben-

efits and commodities. Trees play a key role in the

major biogeochemical cycles, including water, oxy-

gen, and nitrogen. Notably, forests are second only to

oceans in the biological sequestration of carbon, and

forests are recognized for their vital role in regulating

the concentration of the greenhouse gas, CO2. At the

same time, forests are threatened by land clearing for

development and agriculture, introduced pathogens

and insects, and by climate change. A fundamental

need encompassing all of these scientific, economic,

and management issues is a better understanding

of the basic biology of forest trees. As the power of

genetic model systems for biological research became

increasingly obvious, the need for a good tree model

system grew. Gradually, Populus – a genus consist-

ing of over 30 species with a wide geographic distri-

bution - developed into the prime model system for

tree research. With the advent of Populus as a full-

fleshed model system for plant genetic and genomics,

tools are now available for plant researchers to explore

these fascinating aspects of tree biology. Genetics and

Genomics of Populus provides an indepth descrip-

tion of the genetic and genomic tools and approaches

for Populus, examines the biology that has been elu-

cidated using genomics, and looks to the future of

this unique model plant. This volume is designed to

serve both experienced Populus researchers and new-

comers to the field. Contributors to the volume are

a blend of researchers, some who have spent most

of their research career on Populus and others that

have moved to Populus from other model systems.

Research on Populus forms a useful complement to

research on Arabidopsis. In fact, many plant species

found in nature are – in terms of the life history and

genetics – more similar to Populus than to Arabidop-

sis. Thus, the genetic and genomic strategies and tools

developed by the Populus community, and showcased

in this volume, will hopefully provide inspiration for

researchers working in other, less well developed,

systems. Stefan Jansson is Professor at Umeå Plant

Science Centre, Department of Plant Physiology,

Umeå University. He was the European coordina-

tor during the Populus genome sequencing initia-

tive, and has a research focus on natural variation and

autumn senescence. Andrew T. Groover studies the

developmental biology of forest trees, with a primary

focus on secondary growth and wood formation. He

is a Geneticist and Director of the Institute of For-




springer.com Plant Pathology 19

est Genetics, US Forest Service, in Davis California.

Rishikesh P. Bhalarao is Professor at Umeå Plant Sci-

ence Centre, Department of Forest Genetics and Plant

Physiology, Swedish University of Agricultural Sci-

ences. His primary research interests are auxin signal-

ing and seasonal activity/dormancy transitions of the

cambium.


Due March 2010

2010. Approx. 385 p. 49 illus. (Plant Genetics and Genomics:

Crops and Models, 8)

978-1-4419-1540-5 ▶ 149,95 €

Plant Pathology

A. Ciancio, K. Mukerji

Integrated Management of

Arthropod Pests and Insect Borne

Diseases

The fifth and last Volume of this IPMD series reviews,

in a multi-disciplinary approach, recent achievements

in crop protection and integrated management of

arthropod pests. The volume is organized in a first

section covering IPM in citrus productions, a Sec-

ond one dealing with advancements in the integra-

tion of management technologies and a last section

covering mites and their biological control agents. As

for the previous volumes, we attempted to provide

an informative coverage for a broad range of agricul-

tural systems and situations. The chapters are mainly

organized and centered on crops, with a particular

emphasis on citrus. This is one of the main crops in

which biological control and IPM approaches were

tested successfully, and the experience gained herein

may indeed result helpful for IMP efforts deployed

worldwide on other crops and/or cropping systems.

Chapters in Section 2 review the integration of insect

and disease management options in pecan crops, the

application of remote sensing technologies, the sta-

tus of knowledge about plant defense compounds

and their potentials. For IPM of invasive species, an

update is provided on the experience gained on the

Red Palm Weevil (RPW) in Egypt. Long-term tech-

nological solutions for IPM in forests and park areas

through aerial treatments with Bt spores concludes

this Section. Finally, in Section 3, updated reviews

about biological control agents of mites are provided.


Due March 2010

2010. XIV, 362 p. (Integrated Management of Plant Pests

and Diseases, 5)

978-90-481-2463-3 ▶ 149,95 €

Forthcoming

R. Ehlers

Regulation of Biological Control

Agents in Europe

Biological control agents can substitute hazardous

pesticides and provide environmentally safe and sus-

tainable control of pests, diseases and weeds. Often,

exaggerating registration requirements prevent or

delay market introduction of micro-organisms,

semiochemicals and botanicals. This book is the result

of the Europe-wide, two-year policy support action

REBECA, a forum for representatives of academia,

regulation authorities and biocontrol industry to dis-

cuss improved regulation rules. It provides a com-

prehensive review on existing data requirements and

registration procedures. Risks and benefits of bio-

control in relation to trade-off effects resulting from

unbalanced regulation are discussed. As a result, pro-

posals for innovative and balanced regulation pro-

cedures are presented including recommendations

how to accelerate the authorisation process. Consid-

ering concerns about possible non-target effects of

beneficial insects, mites and nematodes this book pro-

poses harmonisation of regulation rules and provides

comprehensive material on the data requirements for

authorisation, including guidelines for completion of

possible application forms for macro-organisms. This

book is a valuable source on state-of-the-art registra-

tion practice and possible policy steps to promote fur-

ther introduction of biocontrol in agriculture practice.


Due March 2010

2010. Approx. 325 p.

978-90-481-3663-6 ▶ approx. 130,00 €

Plant Physiology

Forthcoming

V. Demidchik, F. Maathuis

Ion Channels and Plant Stress

Responses

This book aims to provide a range of perspectives on

an area that is very topical at present in plant biol-

ogy: the role of ion channels in plant stress responses.

Functions of cation and anion channels in the sens-

ing and encoding of major biotic and abiotic stimuli,

stress signal transduction and metabolism adjustment

are examined at the cellular and molecular levels. Par-

ticular emphases of the book are on new insights into

plant Ca2+ signaling, salinity tolerance mechanisms,

cyclic nucleotide gated channels and the regulation of

stress reactions among oxygen-derived species.


Due February 2010

2010. X, 240 p. 28 illus., 15 in color. (Signaling and

Communication in Plants, )

978-3-642-10493-0 ▶ 129,95 €

R. Hell, R. Mendel

Cell Biology of Metals and

Nutrients

Plants are composed of 17 essential and at least 5 ben-

eficial elements, and these must be taken up as metal

or nutrient ions to allow for growth and cell divi-

sion. Much effort has been devoted to studying the

physiology and biochemistry of metals and nutrients

in plants. The aspect of cell biology, however, is an

emerging new field and much needs to be learned

about sensing, long-distance communication within

plants, and cellular signal transduction chains in

response to environmental stress. Cellular malfunc-

tion and consequently disease result when any of the

key steps in metal and nutrient homeostasis are dis-

rupted. Working together, leading experts in their

respective fields provide a new concept that reaches

beyond plant nutrition and plasmalemma transport

into cellular physiology. Each chapter contains basic

information on uptake, physiological function, defi-

ciency and toxicity syndromes, long-distance and

intracellular transport. The discussion is devoted to

metals and nutrients where recent progress has been

made and highlights the aspects of homeostasis and

sensing, signaling and regulation, drawing parallels to

other organisms including humans. Finally, the book

identifies gaps in our current knowledge and lays out

future research directions.


Due February 2010

2010. Approx. 300 p. 23 illus., 15 in color. (Plant Cell

Monographs, 17)

978-3-642-10612-5 ▶ 129,95 €






20 Plant Sciences (general) springer.com

S. Mancuso, S. Shabala

Waterlogging Signalling and

Tolerance in Plants

Waterlogging is a major problem for plant cultivation

in many regions of the world. This book combines

both academic and practical aspects of this topic.

Based on recent progress in cell and molecular biol-

ogy, various facets of waterlogging signalling and tol-

erance are addressed, starting from the molecular

level, through membrane transport, cells and plant

organs, up to the whole organism. Leading scientists

contribute 13 chapters grouped into the following

main parts: Whole-Plant Regulation Intracellular Sig-

nalling Membrane Transporters in Waterlogging Tol-

erance Agronomical and Environmental Aspects This

work offers a universal handbook for any researcher

or agronomist interested in the impact of waterlog-

ging in plants.


Due April 2010


978-3-642-10304-9 ▶ 149,95 €

K. Ramawat

Desert Plants

Biology and Biotechnology

Vast areas of Earth's landmass exist as deserts, repre-

senting quite distinct ecosystems. Desert plants and

animals have evolved specialised survival strategies

to cope with the harsh environment of high temper-

atures and scarce water resources. The life-support-

ing vegetation of deserts is characterised by its unique

reproductive biology, metabolism and adaptive char-

acters. Plants like Prosopis cineraria and date palm

form the basis of the rural economy in many coun-

tries, and are of great cultural importance; Jojoba

and Jatropha have attracted interest as non-conven-

tional sources of industrial oil and biodiesel. This

book includes chapters on the seed biology, reproduc-

tion, mycorrhizae, stress physiology, and metabolism

of desert plants, and describes current biotechnolog-

ical approaches to their cultivation. It will be useful

to researchers, teachers and students in the fields of

plant sciences, agriculture, and forestry, and those

involved in the management and conservation of

desert ecosystems.


Due January 2010

2010. XXI, 503 p. 144 illus., 1 in color.

978-3-642-02549-5 ▶ 169,95 €

Forthcoming

C.A. Rebeiz, C. Benning, H.J. Bohnert, H. Daniell, J.K. Hoober,

H.K. Lichtenthaler, A.R. Portis, B.C. Tripathy

The Chloroplast

Basics and Applications

The world population is expected to increase to 9 bil-

lion by the year 2050 which will generate food and

fuel shortages. Since it will be difficult to increase

the land area under cultivation without serious envi-

ronmental consequences, higher productivity for

biomass is required. Improvement in photosynthetic

efficiency would require increased knowledge and

deeper understanding of :(a) the biosynthesis of pho-

tosynthetic membrane components such as hemes,

chlorophylls, carotenoids, quinones, and lipids; (b)

photosynthetic membrane apoprotein biosynthe-

sis; (c) the biosynthesis and regulation of the assem-

bly of pigment-apoprotein complexes; and (d) the

complexities of carbon sensing, biosynthesis and

allocation. These goals may be accomplished by bio-

engineering of chloroplasts with higher photosyn-

thetic efficiency and superior adaptation to various

stresses and/or alteration of the kinetic properties of

the CO2-assimilating enzyme, Rubisco. Advances

towards this goal are addressed in this volume that

will foster cooperation between biochemists and

molecular biologists, scientists involved in photosyn-

thesis research and biotechnologists involved in plant

and plastid genomics and transformation. We envi-

sion future research to focus attention on "Chloro-

plast Bioengineering" as an integrated novel field

of research. This book is designed for graduate stu-

dents and researchers in chlorophyll metabolism,

integrative plant biology, plant physiology, plant bio-

chemistry, plant molecular biology, biotechnology,

bioenergy and biofuels.


Due April 2010

2010. Approx. 500 p. (Advances in Photosynthesis and

Respiration, 31)

978-90-481-8530-6 ▶ approx. 209,00 €

Plant Sciences (general)

B. Boller, U.K. Posselt, F. Veronesi

Fodder Crops and Amenity

Grasses

Grassland provides the forage basis to feed ruminant

animals for the production of meat and milk ever

since their domestication. With the introduction of

improved crop rotations at the end of the sixteenth

century, grasses and legumes began to be also grown

to an important extent as forage crops on arable land.

In the last decades the importance of amenity grasses

increased markedly, due to the demand of the soci-

ety for new usages like landscape protection. Some

milestones in forage crop breeding since it’s begin-

ning around 1900 were the invention of the polycross

leading to the replacement of open pollinated vari-

eties by synthetic varieties, progeny testing, breed-

ing of amenity grasses, induction of tetraploidy in

the ryegrasses and red clover, and the introduction

and application of molecular tools. The invention of

the forage plot harvester, computers, NIRS and other

new technologies have led to a tremendous increase

in breeding intensity. The aim of "Fodder Crops and

Amenity Grasses", the fifth volume in the book series

"Handbook of Plant Breeding", is to collect current

knowledge in breeding research to serve breeders as

well as researchers, students, but also their academic

teachers. It may be regarded as a scientific knowl-

edge platform which provides practical plant breed-

ers with new scientific information, but also to make

molecular biologists more familiar with the peculiar-

ities of breeding the various species of fodder crops

and amenity grasses. Because forage crops have many

topics in common and to avoid redundancy, the vol-

ume starts with 9 general chapters devoted to: the

role of forage crops in multifunctional agriculture,

genetic resources, breeding methodology, molec-

ular tools, breeding objectives in forages as well as

amenity grasses, breeding for seed yield, variety test-

ing and release, and an outlook into the future. The

second part comprises the 9 most important groups

of temperate species among the grasses, clovers and

alfalfa. The chapters have been written by outstand-

ing breeders and scientists with wide experience in

their crops and topics. About the editors: They are

the acting (BB), past (UKP) and past-past (FV) chair-

man of the section ‘Fodder Crops and Amenity Grass

Breeding’ of EUCARPIA, the European Association

for Research on Plant Breeding. Beat Boller is a clover

and grass breeder at Agroscope Reckenholz-Tänikon

in Zürich, a research station of the Swiss Federal

Department of Economic Affairs. Between 1989 and

2009, he created and released 60 registered cultivars of

11 species, including red and white clover, ryegrasses,




springer.com Plant Systematics / Taxonomy / Biogeography 21

fescues, and cocksfoot, which are listed in many Euro-

pean countries. He also has wide experience in genetic

resources of forages, having acted as chairman of the

Forages Working Group of ECPGR between 2002

and 2007. Since 2008, he is President designate of

EUCARPIA. Ulrich K. Posselt is a research plant

breeder and was head of the forage research group at

the State Plant Breeding Institute of the University of

Hohenheim until his retirement in 2008. His research

activities were on the ryegrasses and mainly devoted

to breeding methodology, disease resistance, appli-

cation of biotechnological techniques and molecular

tools. This lead to more than 50 scientific publications

in reviewed journals and conference proceedings. He

was involved in teaching forage crop breeding and

training of Ph.D. and MS students. Fabio Veronesi

is professor of plant biotechnologies and chair of the

MS degree in human feeding and nutrition sciences

at University of Perugia., where he is also in charge

of the PhD program in botany and agroenvironmen-

tal, animal and food biotechnologies. His research

activities have been mainly devoted to forage plant

breeding (with special emphasis for alfalfa), meiotic

mutations, transformation technologies applied to

alfalfa, germplasm collection, conservation and eval-

uation, environmental and human impacts of genet-

ically engineered plants. This lead to more than 70

technical papers in reviewed journals.


Due January 2010

2010. XI, 523 p. (Handbook of Plant Breeding, 5)

978-1-4419-0759-2 ▶ 149,95 €

S.M. Jain, S.J. Ochatt

Protocols for In Vitro Propagation

of Ornamental Plants

While ornamental plants are produced mainly for

their aesthetic value, the propagation and improve-

ment of quality attributes such as leaf types, flower

colour and fragrance, longevity and form, plant shape

and architecture, and the creation of novel variation

are important economic goals for the expanding orna-

mental industry. In Protocols for In Vitro Propaga-

tion of Ornamental Plants, leading researchers in the

field compile step-wise protocols for rapid plant mul-

tiplication and in vitro storage of major commercially

viable ornamental plants. Divided into two sections,

Section A contains chapters mainly on micropropa-

gation of cut and pot flowers with detailed protocols

involving in vitro culture-explants, medium prepara-

tion, detailed medium table, shoot initiation and pro-

liferation, root induction, in vitro plant hardening,

and field transfer, and Section B delves into reviews

on topics such as in vitro production of sweet peas,

the status of transgenics in ornamental plants, in vitro

conservation, the status of floriculture in Europe,

azalea phylogeny, and thin cell layers. As part of the

highly successful Methods in Molecular Biology™

series, chapters include introductions to their respec-

tive topics, lists of the necessary materials, step-by-

step laboratory protocols, and notes on troubleshoot-

ing and avoiding known pitfalls.Comprehensive and

clear, Protocols for In Vitro Propagation of Ornamen-

tal Plants presents key techniques that will be of great

use to floriculturists, researchers, commercial com-

panies, biotechnologists, and students dealing with

ornamental plants.


Due January 2010

2010. XIV, 400 p. 108 illus., 13 in color. (Methods in


978-1-60327-390-9 ▶ 89,95 €

I. Kovalchuk, F.J. Zemp

Plant Epigenetics


The past fifteen years have witnessed major advances

in epigenetics, one of the most popular and quickly

evolving fields of modern science. In Plant Epigenet-

ics: Methods and Protocols, expert researchers explore

the most recent developments, examining in great

detail the contribution of epigenetic regulation to cell

function in plants. Chapters include a variety of pro-

tocols for studying the function of small non-coding

RNAs, DNA methylation, and histone modifications

in plants, often in different degrees of complexity.

This volume describes bioinformatic approaches to

the analysis of high-throughput data, such as bisul-

fite sequencing and Chip-on-chip assays. It features

much-desired protocols for plant transgenesis and the

analysis of genome stability, with a detailed discus-

sion of their applications to epigenetic studies. Com-

posed in the highly successful Methods in Molecular

Biology™ series format, each chapter contains a brief

introduction, step-by-step methods, a list of necessary

materials, and a Notes section which shares tips on

troubleshooting and avoiding known pitfalls. Wide-

ranging and innovative, Plant Epigenetics: Methods

and Protocols is an invaluable manual designed to

help researchers uncover the undiscovered and unex-

plained phenomena in plant biology.


Due April 2010



978-1-60761-645-0 ▶ 94,95 €

S.S. Yadav, D.L. McNeil, R. Redden, S.A. Patil

Climate Change and Management

of Cool Season Grain Legume

Crops

Legumes are a major source of food, nutrition and

feed worldwide particularly in developing nations.

Climate change is likely to exacerbate the effects

of heat and drought stress in the future as well as

push legumes production into more marginal lands.

The goal of this book is to present an analysis of the

production and science issues we are likely to face

now and in the future. This book covers all aspect

of legume production management technologies,

plant ecological response, nutrients management,

biological nitrogen fixation, molecular approaches,

potential cultivars, biodiversity management under

climate change. Also covered are various aspects

of legume management under climate change and

include; Production management technology, ecol-

ogy & adaptation, diseases, and international trade.

Physiology and crops response to nutrients, drought,

salinity, and water use efficiency. Biodiversity man-

agement, molecular approaches and biological Nitro-

gen fixation. Climate change and strategies This

book presents the most comprehensive and up to

date review of research on different cool season grain

legume crops, nutrients management, biotic and abi-

otic stresses management, agronomical approaches

for drought management, salinity, drought, weed

management and water use efficiency, impact on

international trade around the world. This book will

be of great value to legume breeders, grain producers,

agronomists, scientists, academic researchers, gradu-

ates students, traders, and farmers in the developing

and the developed world.


Due February 2010

2010. Approx. 600 p.

978-90-481-3708-4 ▶ approx. 169,95 €

Plant Systematics / Taxonomy /

Biogeography

Forthcoming

K. Ammann

Sorghum Biology

Sorghum is Africa's contribution to the world's

top crops and belongs to the elite handful of plants





22 Protein Science springer.com

that collectively provide more than 85 percent of

all human energy. Today, it is the dietary staple of

more than 500 million people in more than 30 coun-

tries. Only rice, wheat, maize, and potatoes surpass

it in feeding the human race. Nevertheless Sorghum

receives merely a fraction of the attention it warrants

and produces merely a fraction of what it could. A

growing number of researchers already see that a new

and enlightened Sorghum era is just around the cor-

ner. Accorded research support at a level comparable

to that devoted worldwide to wheat or rice or maize,

Sorghum could contribute a great deal more to food

supplies than it does at present. And it would con-

tribute most to those regions and peoples in greatest

need. The book presented should help to synthesize

the literature and achievements in the research on the

biology of Sorghum in the wake of the 21st century.


Due March 2010

2010. Approx. 350 p.

978-3-0346-0191-7 ▶ 119,00 €

Forthcoming

M. Zahran

Climate - Vegetation:

Afro-Asian Mediterranean and Red Sea Coastal

Lands

Deserts are unique ecosystems with their own biotic

and abiotic components, and are often rich in renew-

able natural resources, the appropriate management

of which can contribute significantly to the sustain-

able management of desert regions for the welfare of

the people. Yet while there are many books on the

flora of the countries fringing the important desert

countries of the Mediterranean and Red Seas, there

or few books reporting on their ecophysiology and

vegetation ecology. This book presents the vegeta-

tion types of the African and Asian countries of the

Mediterranean and Red Sea coastal regions, and dis-

cusses the ecological threats and economic appli-

cations of these critical resources. In particular, it

examines the relationships between climate and vege-

tation, and discusses these within the context of deser-

tification, agro-industrial applications, ecotourism

and sustainable development. The book will provide

a valuable reference for researchers and graduate stu-

dents involved in plant ecology, biogeography, eco-

nomic botany and environmental management in

the Afro-Asian Mediterranean and Red Sea coastal

regions, as well as other desert regions around the

world.


Due January 2010

2010. Approx. 500 p. (Plant and Vegetation, 4)

978-90-481-8594-8 ▶ approx. 149,95 €

Protein Science

Y. Endo, K. Takai, T. Ueda

Cell-Free Protein Production


During the past decade as the data on gene sequences

and expression patterns rapidly accumulated, cell-

free protein synthesis technology has also experi-

enced a revolution, becoming a powerful tool for

the preparation of proteins for their functional and

structural analysis. In Cell-Free Protein Production:

Methods and Protocols, experts in the field contribute

detailed techniques, the uses of which expand deep

into the studies of biochemistry, molecular biology,

and biotechnology. Beginning briefly with basic meth-

ods and historical aspects, the book continues with

thorough coverage of protein preparation methods,

the preparation of proteins that are generally difficult

to prepare in their functional forms, applications of

the cell-free technologies to protein engineering, as

well as some methods that are expected to constitute a

part of future technologies. Written in the highly suc-

cessful Methods in Molecular Biology™ series format,

the chapters include introductions to their respective

topics, lists of the necessary materials and reagents,

step-by-step, readily reproducible laboratory pro-

tocols, and notes on troubleshooting and avoiding

known pitfalls. Authoritative and cutting-edge, Cell-

Free Protein Production: Methods and Protocols aims

to help researchers continue the growth of the vital

exploration of cell-free sciences and technologies in

order to better understand the dynamic lives of cells.


Due January 2010

2010. XI, 261 p. 65 illus., 3 in color. (Methods in Molecular

Biology, 607)

978-1-60327-330-5 ▶ 79,95 €

Proteomics

Forthcoming

F. Liu, S. Altman

Ribonuclease P

Ribonuclease P (RNaseP), a ribonucleoprotein, is an

essential tRNA processing enzyme found in all living

organisms. Since its discovery almost 40 years ago,

research on RNase P has led to the discovery of the

catalytic properties of RNA, and of the only known,

naturally occurring RNA enzymes, RNase P catalytic

RNA. The description of the catalytic properties of

RNA has provided fundamental insight into the RNA

world and these catalytic properties are being har-

nessed as therapeutic and prevention strategies for

acquired and inherited diseases. Ribonuclease P is the

first book to provide a comprehensive collection cov-

ering all aspects of current research on RNase P. The

topics include kinetic and structural analysis, mech-

anism of catalysis, and its regulation and biogenesis

in prokaryotes, eukaryotes, and organelles. Further-

more, research progresses on developing RNase P

as a potential drug target for antimicrobial develop-

ment and as a gene-targeting tool for anti-infective

and anticancer therapy are also included. This book

should be of general interests to molecular biologists

and biochemists in both the academic section and

pharmaceutical industry.


Due January 2010

2010. XVI, 284 p. 53 illus., 23 in color. (Protein Reviews, 10)

978-1-4419-1141-4 ▶ 139,95 €

Stem Cells

S. Efrat

Stem Cell Therapy for Diabetes

Stem Cell Therapy for Diabetes, one of the latest

installments of the Stem Cell Biology and Regen-

erative Medicine series, reviews the three main

approaches for generation of sufficient numbers of

insulin-producing cells for restoration of an adequate

beta-cell mass: beta-cell expansion, stem-cell differen-

tiation, and nuclear reprogramming. Adeptly collect-

ing the research of the leading scientists in the field,

Stem Cell Therapy for Diabetes compares the mer-

its of employing autologous versus banked allogeneic

cell sources for generation of surrogate beta cells, and

addresses tissue engineering and ways for cell protec-

tion from recurring autoimmunity and graft rejection.

Sure to pique the interest of investigators, clinicians,

and students of stem-cell application in regenera-

tive medicine, and cell therapy of diabetes, Stem Cell

Therapy for Diabetes provides essential reading for

those especially interested in tracking the progress





springer.com Zoology (general) 23

in applying of one of the most exciting new develop-

ments in bio-medicine towards a cure for diabetes.


Due January 2010

2010. XI, 291 p. 58 illus., 20 in color. (Stem Cell Biology and

Regenerative Medicine, )

978-1-60761-365-7 ▶ 119,95 €

Zoology (general)

Forthcoming

I.J. Duncan, P. Hawkins

The Welfare of Domestic Fowl and

Other Captive Birds

This book describes the welfare implications of keep-

ing wild and domesticated birds in captivity. The

environmental and social requirements of various

avian species are discussed and suggestions made for

appropriate housing and management techniques.

Particular attention is paid to human-bird interac-

tions and their impact on the behaviour and welfare

of the birds involved. Training methods for compan-

ion birds are also described. Possible future trends in

keeping birds in captivity are discussed in relation to

evolving laws and codes for both wild and domesti-

cated birds and in the light of developing ethical atti-

tudes to animals. The book will be invaluable to all

those who keep birds including poultry farmers, pet

owners, and managers and caretakers of birds kept in

laboratories, zoos, wildlife aviaries, and rehabilitation

centres. It will also be of great interest to poultry pro-

duction, zoology, wildlife and veterinary students.


Due January 2010

2010. Approx. 290 p. (Animal Welfare, 9)

978-90-481-3649-0 ▶ 129,95 €

R. Gerecke

Süßwasserfauna von

Mitteleuropa, Bd. 7/2-2

Chelicerata

Acari 2

Chelicerata are a basically terrestrial group of inver-

tebrates, including many clades whose representa-

tives have never found an evolutionary way to aquatic

live. An exception is made by some spiders and the

highly diverse aquatic mites which in inland water

habitats are represented by members of numerous dif-

ferent clades having evolved an aquatic or amphibi-

ous lifestyle along various evolutionary pathways.

For the first time in limnofaunistic bibliography, the

present taxonomic knowledge about these differ-

ent groups of invertebrates is brought together in an

overview for the Central-European fauna. This sec-

ond volume includes taxonomic keys and ecological

information for the two species-rich superfamilies

Hydryphantoidea and Lebertioidea of the freshwa-

ter mites (Hydrachnidia). A further volume in prepa-

ration will include the remaining two superfamilies,

Hygrobatoidea and Arrenuroidea. The chelicerata

volumes of this series are a basic tool for all limnolo-

gists interested in diversity and ecology - in particu-

lar for biologists investigating the ecotones between

ground- and surface water, between benthos and

plankton, and between water and land.


Due March 2010

2010. Approx. 240 p. (Süßwasserfauna von Mitteleuropa, )

978-3-8274-1894-4 ▶ 130,79 €




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