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Supplementary Fig. 1 A B Bcl-xL +/+ Bcl-xL -/- Mcl-1 +/+ Mcl-1 -/-

Supplementary Fig. 1

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A. Bcl-xL -/-. Bcl-xL +/+. B. Mcl-1 -/-. Mcl-1 +/+. Supplementary Fig. 1. A. Bcl-xL -/- No.1 T1. Bcl-xL -/- No.3 T1. Bcl-xL +/+. Bcl-xL -/- No.1NT. Bcl-xL -/- No.1 T2. Bcl-xL -/- No.2 NT. Bcl-xL -/- No.2 T1. Bcl-xL -/- No.2 T2. Bcl-xL -/- No.2 T3. Bcl-xL -/- No.3 NT. - PowerPoint PPT Presentation

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Page 1: Supplementary Fig. 1

Supplementary Fig. 1

A

B

Bcl-xL+/+ Bcl-xL-/-

Mcl-1+/+ Mcl-1-/-

Page 2: Supplementary Fig. 1

Supplementary Fig. 2

Mcl-1

Beta actin

Bcl

-xL+

/+

Bcl

-xL+

/+

Bcl

-xL-/

- No

.1N

TB

cl-x

L-/- N

o.1

T1

Bcl

-xL-/

- No

.1 T

2B

cl-x

L-/- N

o.2

NT

Bcl

-xL-/

- No

.2 T

1

Bcl

-xL-/

- No

.2 T

2B

cl-x

L-/- N

o.2

T3

Bcl

-xL+

/+

Bcl

-xL+

/+

Bcl

-xL-/

- No

.3 N

TB

cl-x

L-/- N

o.3

T1

Bcl

-xL-/

- No

.4 N

TB

cl-x

L-/- N

o.4

T1

Bcl

-xL-/

- No

.4 T

2B

cl-x

L-/- N

o.4

T3

Bcl

-xL-/

- No

.5 N

TB

cl-x

L-/- N

o.5

T1

A

B

Bcl-xL

Beta actin

Mcl

-1+

/+

Mcl

-1+

/+

Mcl

-1-/

- No

.1 N

TM

cl-1

-/- N

o 1

T1

Mcl

-1-/

- No

2 N

TM

cl-1

-/- N

o 2

T1

Mcl

-1-/

- No

3 N

TM

cl-1

-/- N

o 3

T1

Mcl

-1-/

- No

3 T

2

Mcl

-1-/

- No

6 T

1M

cl-1

-/- N

o 6

T2

Mcl

-1-/

- No

4 N

TM

cl-1

-/- N

o 4

T1

Mcl

-1-/

- No

4 T

2M

cl-1

-/- N

o 5

NT

Mcl

-1-/

- No

5 T

1M

cl-1

-/- N

o 5

T2

Mcl

-1-/

- No

5 T

3

Mcl

-1-/

- No

6 N

T

Mcl

-1-/

- No

3 T

3

Mcl

-1-/

- No

3 T

4

Mcl

-1+

/+

Page 3: Supplementary Fig. 1

Supplementary Fig. 3

Mcl-1-/- TumorBcl-xL-/- Tumor

Page 4: Supplementary Fig. 1

A

Supplementary Fig. 4

Mcl-1+/+ Mcl-1-/-

Bak+/+ Bak-/- Bak+/+ Bak-/-

Ki6

7

0

2

4

6

8

10

12

Mcl-1-/-

Bak

Ki-6

7 p

osi

tve

nu

cli

(+/+)

Mcl-1+/+

* **

B

(-/-) (-/-)(+/+)

Page 5: Supplementary Fig. 1

Supplementary Fig. 5

0

0.1

0.2

0.3

0.4

0.5

0.6

0.7

Mcl-1-/-

*

Siri

us

red

sta

ine

d a

rea

(%

)

Bak+/+ Mcl-1-/- Bak-/- Mcl-1-/-

Bak (+/+) (-/-)


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