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Supplementary Figure S3 p-Src t-Src t-AKT p-AKT p-p70S6K t-p70S6K p-S6 t-S6 β-actin p-Fox01/3a DMSO Rap 0 1 2 3 4 p:t-AKT DMSO Rap 0 1 2 3 4 DMS O Das Rap Com bo DM S O Das Rap Com bo 1hr 24hr MCF7 0 2 4 6 0 2 4 6 DMS O Das Rap Combo DMS O Das Rap Combo 1hr 24hr MDA-MB-231 0 1 2 3 0 1 2 3 DMSO Das Rap Com bo DMSO Das Rap Combo 1hr 24hr BT474 Analysis of mTOR and AKT signaling in breast cancer cell lines treated with dasatinib and rapamycin

Supplementary Figure S3

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Supplementary Figure S3. Analysis of mTOR and AKT signaling in breast cancer cell lines treated with dasatinib and rapamycin. MCF7. MDA-MB-231. BT474. 1hr. 24hr. 1hr. 24hr. 1hr. 24hr. Combo. Combo. Combo. Combo. Combo. Combo. DMSO. DMSO. DMSO. DMSO. DMSO. DMSO. Rap. - PowerPoint PPT Presentation

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Page 1: Supplementary  Figure S3

Supplementary Figure S3

p-Src

t-Src

t-AKT

p-AKT

p-p70S6K

t-p70S6K

p-S6

t-S6

β-actin

p-Fox01/3a

DMSO Das Rap

Combo01234

p:t-

AKT

DMSO Das Rap

Combo01234

DMSO

Das Rap

Com

bo

DMSO

Das Rap

Com

bo

1hr 24hr

MCF7

DMSO Das Rap

Combo0123456

DMSO Das Rap

Combo0123456

DMSO

Das Rap

Com

bo

DMSO

Das Rap

Com

bo

1hr 24hr

MDA-MB-231

DMSO Das Rap

Combo0

0.51

1.52

2.53

DMSO Das Rap

Combo0

1

2

3

DMSO

Das Rap

Combo

DMSO

Das Rap

Combo

1hr 24hr

BT474

Analysis of mTOR and AKT signaling in breast cancer cell lines treated with dasatinib and rapamycin