Ung Dung Pro Bio Tics Trong San Xuat Va Bao Ve Suc Khoe

8/3/2019 Ung Dung Pro Bio Tics Trong San Xuat Va Bao Ve Suc Khoe

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SEMENAR CHUYN

CH :

ngDngCa Probiotics Trong SnXut V BoV Con Ngi

GVHD: NGUYN HU HIP NHM SV THC HIN

1. Ph Cng Ch 30968092. ThKiuDim 30968113. LngNgc Hn 30923974. Bi Th Trc Linh 30968315. L TrngNgha 30968406. Phm Hong Nam 30968377. Nguyn Thnh Tm 30924378. L Thy Quyn 3092504

9. V ThDimNgc 3092425


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MC LC

A.tvnB.Ni dung bo coI. Giithiu chung v probioticsII. Cc loi vi khunthng c trong

probioticsIII. Cchhatngca probioticsIV. Vai tr ca probioticsV. Nhnghnch v ri ro

VI. Li ch v timnngVII. Tnh hnh sdng probiotic Vit NamC. Ktlun


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A. tvn

Khi nghe ni c vi khun trong thcphm, nhiungithng git mnhlo lng.Tuy nhin, khngphi lni kinh hong vv sinh an tonthcphmnhlmtng m l mt xu

hngmi trn ton thgii: B sunghng tnhng vi khun c liProbiotics vo ch dinh dng hngngy tngcngsckhe. Vy

probiotics tc ng nh th no ln kch cng nh vi sinh vt xung quanh

mi trng c probiotics. y l vn m nhm chng ti t ra tin hnhseminar ny nhm tm hiu k hn vthut t probiotic

Sn phm probiotics


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I. Giithiu chung v probiotics

1. Khi nimv probioticTheo nhnghacaTchc y tthgii

(WHO), Probiotics l nhng vi sinhvt cn sng, khi ca vo cthmtlngys c li cho sckheca k ch.

Ni cch khc:Probiotic l sb sung vo khuphn(cho ngi v vt nui)bngnhng vikhun (VK) v men c litngcng qu trnh chuyn ha thcn

hocngnngamtsbnhngrut. Bng cch , vi sinh vt (VSV)thngc dng l VK lactic (haichngcsdngphbinnht lLactobacillus v Bifidobacterium)


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2. Lchsca Probitics

Khong 2500 nm trc cng nguyn, s tiu th sachua (mt sn phm sa ln men) c ng h duytr sc khe tt (Chopra v Doiphode, 2002)

uthk XX, E.Metchnikoff (Nga) lnu tin pht

hin tc dngttcamt vi VK v ng cho rng c thiuchnhqunth VSV trong rut, c th thay thnhngVSV c hibngnhng VK c ch.

A.Nissle (c) nm 1917 phn lpmtchng Escherichia

coli Nm 1935, ngi ta pht hinmtschng l

Lactobacillus acidophilus c hot tnh mnh khi a vongrutcangi.


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II.Cc loi probiotics thngcsdng1. Bifidobacterium Cc vi khun bn ny c nhiu li ch nh lp

hng ro c ch s pht trin ca nhng vi khungy bnh, cnh tranh v ch , thc n vi cctc nhn gy tiu chy nh Rotavirus chng hn.Cc vi khun ny lm gim nhim trng ngtiu ho, gim cholesterol, tng cng sc khng chng li nhim trng, tng hp thu v tiuha cc cht m, tng hp sinh t nhm B, K

Thng s dng nh Bifidobacterium breve,Bifidobacterium infantis, Bifidobacterium longumcng c s dng trong ch phm probiotics.

Bifidobacterium bifidum


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2.Lactobacillus

a. Lactobacillus acidophilus

- Lactobacillus acidophilus l mt probiotic xy ra t nhin trongng rut ca con ngi v trong m o.

- Lactobacillus acidophilus c kh nng sng 2 ngy trong dch v, 5ngy trong dch mt tinh khit, 8 ngy trong dch trng.

- Lactobacillus acidophilus sn xut acid lactic v cc cht dit khunnh lactocidin, ngn cn s xm nhp v c ch s tng sinh cacc vi khun gy bnh, gip cho c th khng vi nhim khunng rut.

- Lactobacillus acidophilus ng vai tr sinh l quan trng nh tnghp cc vitamin.

- Lactobacillus acidophilus c kh nng bn vng vi 40 loi khngsinh.

Lactobacillus acidophilus


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b. Khun Lactobacillus casei Lactobacillus casei l vi khun

xuthint nhin trong mingv rut. N gip kim sot tiuchy, htrchcnngmin

dch v lm gimhichngrutkch thch (IBS). Ngoi c nhiu trong sa chua,

Lactobacillus casei c tm

thynhiu trong pho mt lnmen t nhin, liu xanh, dachua, dachut.

Lactobacillus casei


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c. Lactobacillus sprorogenes

C khnng sinh ra lactic acid, acid nyd dng chp thu hon ton v c tnhphnngmindch.

Theo mts bo co th khi sdngLactobacillus sprorogenes liu cao (360triu bo t/ngy) s c khnng lm

gim cholesterol c hi trong mu.

Hnh nh c th [ cu trc]:


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d. Lactobacillus kefir:

L vi sinh vt c y cc c tnh cu men vikhun c li. Trong thnhphnca Lactobacillus kefir c cha cc

cht khong, acid amin quan trng gip cth chnghiphcsckhe.

Tryptophan l mt trong nhng acid amin quan trngc nhiu trong Lactobacillus kefir, c tc dng anthn.

Lactobacillus kefir c chanhiu Ca v Mg, l nhngkhong chtrt quan trng cho hthn kinh

Lactobacillus kefir cung cp Phosphorus,Carbonhydrate, cht bo v cc protein gip t bo cth pht trin v duy tr nnglng.

Lactobacillus kefir


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e. Lactobaccillus casei Shirota

C tc dnghnch cc vi sinh vt c hiv nui dng cc vi sinh vt c li trongngrut, tngcngsckhe cho h tiuha v mindch.

ngdng:- Tng vi khun c ligim vi khun c hi.- Hnchs hnh thnh cc cht c hi, ct, cht gy tbin.

- Cithin cc hotngcangrut.-Ngnngasnhim trng rut.- iutithmindch.- Km hm s hnh thnh v pht trincacc t bo ung th.

Lactobaccillus casei

Shirota


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f. Lactobacillus bulgaricus

Lactobacillus bulgaricuskch thch pngmindch h tiu ha, tngdung np Lactose, sa;ngthikthpviLactobacillus paracaseikch thch sn sinh khngth IgA trong lpnhyrut, cchs nhn ln

ca virus, ngnsthmthuca vi khun vokhoang hthng, trungha ct vi khun.

Lactobacillus bulgaricus


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3. Cc loi khc

Streptococcus lactic-Vi khun ny pht trinttnht trong sa v mts mi trng pha chtsa, y l loi vi khunhiu kh.Nhit thchhp pht trinttnht l30 350C. c tnh sinhha quan trngca chng

l ln men glucose,galactose, lactose, dextrin,nhng khng ln mensaccharose.

Streptococcus lactic


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b. Streptococcus cremoric

Pht trin tt 20250C. Chng lm chosa ng t nhng cng

lm cho sa b nht.Chng thng cho snphm c mi d chu vlm cho sa c chua

thp hn, thng dngtrong ch bin b.Streptococcus cremoric


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III. Cchhatngca probiotics

1. Tc dng khng khunca probiotics Lm gimslng vi khunngnchn cc

mmbnh. Tit ra cc cht khng khun. Vi khun probiotic

to ra cc chtadng m cchc vi khunGram dng v Gram m, gm c cc acid huc, hydrogen peroxide v chtdit vi khun lmbng vi khun.Nhnghpcht ny c th lm

gim khng chnhng sinh vt mang mmbnhc thsngc m cn nhhngns traoichtca vi khun v sto ra cc ct.


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2. Tc dngca probiotics trnbium rut y mnh s lin kt cht gia nhng tbo biu m

Gim vic kch thch bi tit v nhng hu

qu do b vim ca s ly nhim vi khun. y mnh s to ra cc phn t phng v

nh cht nhy.

Tc dng ca probiotics trn biu m rut


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3. Tc dngmindchcaprobiotics Probiotic nh l phng tin phn pht

cc phn t khng vim cho ng rut. y mnh s bo hiu cho t bo ch

lm gim p ng vim.To p ng min dch lm gim dng

Trong thc nghim, ngi ta thy ng

vt th nghim c b sung vi khunlactic tng kh nng chng li bnhtruyn nhim ng rut kh r rt.


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4. Tc dngca probiotics n vikhunngrut Probiotic iu chnh thnh phn cu to

ca vi khun ng rut. Chng to nn s cn bng tm thi ca

h sinh thi ng rut Vi khun probiotic iu ha hot ng

trao i cht ca sinh vt ng rut.Probiotic c th lm gim pH ca b phn

tiu ha v c th theo cch s gy cntr cho hot ng tit ra enzyme ca sinhvt ng rut.

IV V i bi i


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IV.Vai tr ca probiotics1. Trongbovsckhe con ngi

a. Probiotics ivih vi sinhvtngrutngi

Tc dng tch ccca probiotic

trong ngrutngi:- Tc dng tiu ha v chuyn

ha

- Tnghp Vitamin

- Vai tr chngkhun

- Phn hy cc chtc

Hnh minh ha v tc dng ca probiotics


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b. Tng cng min dch chng li nhng bnhnhim trng ng tiu ha Probiotics cchng minh l c th nng cao kh

nngmindch v sc khng carutbng cch tcng tch cc ln mtschcnngcahmindchtiy gip chng tabovsckhotrc cc tc nhn gy

bnht bn ngoi. Probiotics gip y li cc vi khungybnhngrut, sinh si v chimch cc vi khungy hi, cchkhnng gy hica chng, gip cnbnghthng vi sinh c trong ngrut. Probiotic gipbov nim mcrut, gip ngnngastn cng cacc vi khun c hi, lm gimc tnh ca cc chtcc trong thcn, gip hthngmindch, kch thchhotngca enzym tiu ho thcn.

Thit k ch phm sinh hc phng

nga nhim trng ng rut


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c. Probiotics ngn nga tiu chy do thuckhng sinh gy nn

L do dng probiotic iutr tiu chy l cc visinh vt ny c thiuha h vi khun ch

ngrut v tc ngtrctip trn tc nhngybnh. Cc probioticc dng nhmtcch khiphcs cnbng vi sinhb gin onbi cc khng sinh v snhim trng.

yaourt

Probiotics

dng vin

Hnh nh siu viRotavirus, mt

trong nhng

"th phm" gybnh tiu chy

cp


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d. Kthpvi Prebiotic snxutthcphmchcnng Prebiotics c xem l thc n ca nhng

vi khun sng c li cho sc khe. Cc vi khun m prebiotic kch thch l

Bifidobacterium hay Lactobacillus Prebiotic c coi l thc n l tng cho

cc vi khun tt, gip tng cng hot

ng ca Probiotics


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Synbiotic

Synbiotic l skthpgia hai thnhphnPrebiotic v Probiotic. SkthpuimcaPrebiotic & Probiotic lm cho Synbiotic c chcnngnibt l khnngtngcng vi khuntttingrut (Probiotic)v cung cpthcn gipvi khuntt pht trinmnhm v chimuth(Prebiotic)

Thc phm chc nng

Synbiotic


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e. cch vi khun gy let d dyHELICOBACTER PYLORY

Nhiu cng trnh nghin cu cho thy rng chng khunprobiotic c tc dng c ch s pht trin ca khunHelicobacter pyloritrong iu kin in vitro, in vivo vc th nghim trn ngi

Probiotic c ch khunHelicobacter pyloric th theonhng c ch sau: Cnh tranh v tr gn Cnh tranh v dinh dng Kch thch s hnh thnh cht nhy. Hnh thnh cc hp cht khng khun nh acid lactic,

acid acetic, hydrogen peroxide, bacteriocin, c ch hot tnh urease.

Vi khun Helicobacter Pylorytrong nin mcrut

Vi khun Helicobacter Pylory


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f. Probiotics v cc sn phm ln mensa i vi sc khe ngi

Cc snphm ln men truynthngnhdaci, dachua,dakiu, da hnh chamtlng vi khun lactis lntt cho ngrut.

Yagurt hay sa chua ln men l mtthcnngon mingngthicng l mtthcphmchcnngy tnhbdng.

Gnyngi ta c khuynh hng thm vikhun c li vo sabt cho trnhgith cnbngcah vi khunngrut

Sa bt c cha Probiotics Probiotics trong sa chua
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g. Probiotics i vi ph n mang thai v trs sinh

Probiotics c hiu qu i vi ph n mang thai trongkhng cc vi khun m o v cc d ng thng thng

Gim tc dng ph ca vic dng khng sinh trong snkhoa, nguy c sinh non do nhim khun m o, gip ph

n nhanh chng ly li vc dng sau khi sinh Ngn chn nhim khun lin cu nhm B (GBS) khi

mang thai

Nhng nghin cu khoa hc cng ch ra rng, ngi m

khe mnh vi mt ch dinh dng tt trong c bsung Probotics hng ngy s cho ra i mt em b khe,gim thiu nhng e da ca bnh tt nh: bnh i thong, au tim


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2. Trong nng nghip

a. Probiotics ngdngtrong nui trngthysn

Sdng probiotic cho hai mcch: lm thcncho thysn v lm sch mi trngnc lnhnghngngdngmica khoa hc cngngh trong nui trngthysnhin nay.Cc tc ngca probiotics ln hthysn l:

Tngcng phn hy cc chthuc GimnngNitv Phospho Kch thch sinh trngcato Kim sot amoni, nitric hydro sunfua Gim nguy cmcbnh v tngnngsut tm,

c.Thc n cho tm


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b. Tc dngthay ththuc khng sinhiutrtiu chyheo con

Probiotics c coi l snphmyhahn cho vicphng nga v iutrbnh

tiu chynhkhnngnnhh vi sinh vtngrut, nnhstitchtnhyngrut - l hngrobovchcchngsph hoica vi sinh vt chiivibiu m rut.


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c.Probiotics ng dng lm thc n giasc

Khi b sungBacillus subtilischo g s lm tng trng lng c thv tng cng chuyn ha thc n

- S dng c sn chua lm thc n cho gia sc

- S dng b khoai m lm thc n cho gia sc

- Hai loi sn phm ln men t b khoai m sng: ProBio-S v Bio-E.

+ Bio-E l ch phm dng bt kh, c to ra bng cch cy chngnm mc hu ch A.Niger ln b khoai m vi t l 2g mc/kg b.

+Cn ProBio-S li l ch phm dng lng, c sn xut bng cchcho b ti vo nhng bao ti ln ri cy ch phm EM-S chanhiu chng vi sinh vt hu ch nh Bacillus sp., Lactobacillus sp.,Saccharomyces sp

Sn phm lm t b khoaim

B khoai m ti


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3. Trong cng nghipProbiotics ngdng trong cng nghipthcphm

a. Snphm rau ci lnmen

Nguynliu:bpci, cci,da v 1 s rau ci khc.

Visinhvtcsdng:chyu l vi khun Lactic(Leuconostoc mesenteroides,Lactobacillus brevis,Lactobacillus plantarum,Lactobacillus cucumeris,Streptococcus faecalis,Pedioccus cerevisiae).


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b. Sn phm sa ln men

Vi khun lactic l nhm vi khun quan trngnht i vi cng nghip ch bn sa. Cc vikhun tiu biu: Streptococcus Latic,streptococcus Cremoris, cc vi khun sinhhng,... Ngoi ra cnc vi khun propionic.

Sn xut sa chua cn c:Sa nguyn liu ( sa ti, sa c c,sa bt, sa hon nguyn hoc sa ti ch.

Ngun vi sinh vt (ch yu l vi khunlactic).

Trang thit b, mt s ph gia v cngngh sn xut: sn xut sa chua.

Sa

chua


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V. Nhnghnch v ri ro

Probiotics an ton cha c nghin cu klng v mt khoa hc

Probiotics v mt l thuyt c th gy nhimtrng cn c iu tr bng thuc khngsinh, c bit l nhng ngi c iu kinsc khe tim n

Chng cng c th gy ra cc hot ng

khng lnh mnh trao i cht, kch thchqu nhiu ca h thng min dch, hocchuyn i gen (chn vt liu di truyn vot bo).


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VI. Li ch v timnng

iu ho trng hp khng dung nplactose

phng c ung th kt trng

Lm gim cholesterol Ci thin chc phn min dch v phng

nga nhim trng Ci thin hp thu khong VK trong probiotic c tc dng ngn nga

s pht trin VK gy bnh vim rut


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VII. Tnh hnh sdng probiotic Vit Nam

Hin nay Vit Nam ang y mnh vic nghincu sn xut probiotic phc v cho conngi,dng trong chn nui v nui trng thy sn.Trong chn nui v nui trng thy sn do sn phm

tinh ch th gi thnh cn cao nn nc ta hin nayvn s dng ngun nguyn liu ch yu l cc loiph phm ca ngnh nng nghip

dng B.subtilis iu tr bnh i lng, dng mts tho dc trong cha bnh ng rut, kch thchtiu ho... cng l dng probiotic, hy vng trongtng lai gn s c nhiu sn phm mang nhngthng hiu ni ting nh cc nc


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C. Ktlun

Nghin cu pht trin v ng dng probioticvo cuc sng l mt cng vic cn cquan tm v u t nhiu hn na. C nhvy mi tip tc hon thin probiotic em li

hiu qu cao hn, cht lung cuc sng ngyc cao hn, an ton hn p ng nhu cungy cng cao v kht khe ca chng ta. Cth ni , y l bn cht t nhin trung hobn cht t nhin, l s tc ng thn huca con ngi vo t nhin nn m ra mtchin lc pht trin bn vng v an ton


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Ti liu tham kho

Cng ngh sinh hctpnm ( GS.TS. PhmVn Ty, TS V Nguyn Thnh)

http://vi.wikipedia.org

http://vietsciences.free.fr/thuctap_khoahoc/thanhtuukhoahoc

http://Tailieu.vn

Vi sinh vthcGS.TSNguyn Ln Dng
http://vi.wikipedia.org/http://vietsciences.free.fr/thuctap_khoahoc/thanhtuukhoahochttp://vietsciences.free.fr/thuctap_khoahoc/thanhtuukhoahochttp://tailieu.vn/http://tailieu.vn/http://vietsciences.free.fr/thuctap_khoahoc/thanhtuukhoahochttp://vietsciences.free.fr/thuctap_khoahoc/thanhtuukhoahochttp://vi.wikipedia.org/


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