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Keys to the Problems (05/16/2020) Yokoshima Group Group Meeting Problems

Yokoshima Group - 名古屋大学

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Page 1: Yokoshima Group - 名古屋大学

Keys to the Problems (05/16/2020)

Yokoshima Group – Group Meeting Problems

Page 2: Yokoshima Group - 名古屋大学

Keys to the Problems (2020/05/16)

Yokoshima Group – Group Meeting Problems

2

O

OMeO

Me

Ph BCl3

O

OMeO

Me

Ph BCl2

OMeO

MePh

O

BCl2

Cl

OMeO

MePh

OBCl2

OMe

Ph

O

O

MeClCl

BCl2

OMe

Ph

OBCl2

quench

OMe

Ph

OH

Cl

CH3COCl

OMeO

MePh

O BCl2

Cl

Page 3: Yokoshima Group - 名古屋大学

Keys to the Problems (05/16/2020)

Yokoshima Group – Group Meeting Problems

3

Page 4: Yokoshima Group - 名古屋大学

Keys to the Problems (05/23/2020)

Yokoshima Group – Group Meeting Problems

Page 5: Yokoshima Group - 名古屋大学

Keys to the Problems (05/23/2020)

Yokoshima Group – Group Meeting Problems

Page 6: Yokoshima Group - 名古屋大学

Keys to the Problems (05/23/2020)

Yokoshima Group – Group Meeting Problems

Page 7: Yokoshima Group - 名古屋大学

Keys to the Problems (05/23/2020)

Yokoshima Group – Group Meeting Problems

Q3

Page 8: Yokoshima Group - 名古屋大学

Keys to the Problems (05/30/2020)

Yokoshima Group – Group Meeting Problems

CF3 O

O

CF3

O

O

OOH

Me

Me

OMe

TMSO

H

OTBSMe

TMSO

N

N

CF3 O

OCF3 N

O

NMe

Me

CF3 N

O

NMe

Me O

OO

Me

Me

OMe

TMSO

H

OTBSMe

TMSO

CF3

O

O

OO

Me

Me

OMe

TMSO

H

OTBSMe

TMSO

CF3

O

Zn O

OO

Me

Me

OMe

TMSO

H

OTBSMe

TMSO

CF3

O

Zn

OO

Me

Me

OMe

TMSO

H

OTBSMe

TMSO

CF3

O

ZnO

O

O

Me

TMSO

H

OTBSMe

TMSO O

O OHCF3

MeMe

Zn

OAc

H

OAc

O

O

Me

TMSO

H

OTBSMe

TMSO O

OH OHCF3

MeMe

+ H

aqueouswork up

tetracycliccompound

Page 9: Yokoshima Group - 名古屋大学

Keys to the Problems (05/30/2020)

Yokoshima Group – Group Meeting Problems

Page 10: Yokoshima Group - 名古屋大学

Keys to the Problems (05/30/2020)

Yokoshima Group – Group Meeting Problems

2. ⑦

"BY.

..

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18.8kcal lmol Me

My Me- ER]

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Me

hey ⑦ I←

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Another route

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if EE.

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Mey IyetFT⇒ na

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Page 11: Yokoshima Group - 名古屋大学

Keys to the Problems (05/30/2020)

Yokoshima Group – Group Meeting Problems

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